HuGE Literature Finder
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| HapMap-based study: CYP2A13 may be a potential key metabolic enzyme gene in the carcinogenesis of lung cancer in non-smokers. Thoracic cancer 2019 Feb . Hua Feng, Guo Yonglu, Sun Qiang, Yang Leizhou, Gao Fa |
| Genetic Polymorphism of CYP2A6 and Its Relationship with Nicotine Metabolism in Male Bataknese Smokers Suffered from Lung Cancer in Indonesia. Open access Macedonian journal of medical sciences 2018 Jul 6 (7): 1199-1205. Soeroso Noni Novisari, Zain-Hamid Rozaimah, Sinaga Bintang Y M, Sadewa Ahmad Hamim, Syafiuddin Tamsil, Syahruddin Elisna, Tann Gino, Mutiara Er |
Genome-wide association study of familial lung cancer.
Carcinogenesis 2018 Jun . Byun Jinyoung, Schwartz Ann G, Lusk Christine, Wenzlaff Angela S, de Andrade Mariza, Mandal Diptasri, Gaba Colette, Yang Ping, You Ming, Kupert Elena Y, Anderson Marshall W, Han Younghun, Li Yafang, Qian David, Stilp Adrienne, Laurie Cathy, Nelson Sarah, Zheng Wenying, Hung Rayjean J, Gaborieau Valerie, Mckay James, Brennan Paul, Caporaso Neil E, Landi Maria Teresa, Wu Xifeng, McLaughlin John R, Brhane Yonathan, Bossé Yohan, Pinney Susan M, Bailey-Wilson Joan E, Amos Christopher |
| Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population. BMC cancer 2018 May 18 (1): 525. Ezzeldin Nada, El-Lebedy Dalia, Darwish Amira, El Bastawisy Ahmed, Abd Elaziz Shereen Hamdy, Hassan Mirhane Mohamed, Saad-Hussein Am |
| CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study. Carcinogenesis 2017 Feb . Yuan Jian-Min, Nelson Heather H, Carmella Steven G, Wang Renwei, Kuriger-Laber Jacquelyn, Jin Aizhen, Adams-Haduch Jennifer, Hecht Stephen S, Koh Woon-Puay, Murphy Sharon |
| Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer. Pharmacogenetics and genomics 2017 Feb . Tanner Julie-Anne, Henderson Jeffrey A, Buchwald Dedra, Howard Barbara V, Nez Henderson Patricia, Tyndale Rachel |
| Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6. Chemical research in toxicology 2017 Jan 30 (1): 410-419. Murphy Sharon |
| Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.
Cancer research 2016 Oct 76 (19): 5768-5776. Patel Yesha M, Park Sunghim L, Han Younghun, Wilkens Lynne R, Bickeböller Heike, Rosenberger Albert, Caporaso Neil, Landi Maria Teresa, Brüske Irene, Risch Angela, Wei Yongyue, Christiani David C, Brennan Paul, Houlston Richard, McKay James, McLaughlin John, Hung Rayjean, Murphy Sharon, Stram Daniel O, Amos Christopher, Le Marchand Lo |
| Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity. Carcinogenesis 2016 Mar 37 (3): 269-279. Park Sungshim L, Tiirikainen Maarit I, Patel Yesha M, Wilkens Lynne R, Stram Daniel O, Le Marchand Loic, Murphy Sharon |
| Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study. International journal of cancer. Journal international du cancer 2015 Dec . Yuan Jian-Min, Nelson Heather H, Butler Lesley M, Carmella Steven G, Wang Renwei, Kuriger-Laber Jacquelyn K, Adams-Haduch Jennifer, Hecht Stephen S, Gao Yu-Tang, Murphy Sharon |
| CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers. Drug metabolism and pharmacokinetics 2015 Aug 30 (4): 263-8. Hosono Hiroki, Kumondai Masaki, Arai Tomio, Sugimura Haruhiko, Sasaki Takamitsu, Hirasawa Noriyasu, Hiratsuka Masahi |
| Genotyping of wild-type cytochrome P450 2A6 and whole-gene deletion using human blood samples and a multiplex real-time polymerase chain reaction method with dual-labeled probes. Clinica chimica acta; international journal of clinical chemistry 2015 Feb 441 71-4. Shimizu Makiko, Sawaya Ren, Kishimoto Izumi, Yamazaki Hiros |
| CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers--findings from two independent populations. Carcinogenesis 2015 Jan 36 (1): 99-103. Wassenaar Catherine A, Ye Yuanqing, Cai Qiuyin, Aldrich Melinda C, Knight Joanne, Spitz Margaret R, Wu Xifeng, Blot William J, Tyndale Rachel |
| Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PloS one 2015 10 (7): e0126113. Bergen Andrew W, Michel Martha, Nishita Denise, Krasnow Ruth, Javitz Harold S, Conneely Karen N, Lessov-Schlaggar Christina N, Hops Hyman, Zhu Andy Z X, Baurley James W, McClure Jennifer B, Hall Sharon M, Baker Timothy B, Conti David V, Benowitz Neal L, Lerman Caryn, Tyndale Rachel F, Swan Gary E, |
| Role of Metabolic Enzymes P450 (CYP) on Activating Procarcinogen and their Polymorphisms on the Risk of Cancers. Current drug metabolism 2015 16 (10): 850-63. He Xin, Feng Sh |
| A DRD1 polymorphism predisposes to lung cancer among those exposed to secondhand smoke during childhood. Cancer prevention research (Philadelphia, Pa.) 2014 Dec 7 (12): 1210-8. Robles Ana I, Yang Ping, Jen Jin, McClary Andrew C, Calhoun Kara, Bowman Elise D, Vähäkangas Kirsi, Greathouse K Leigh, Wang Yi, Olivo-Marston Susan, Wenzlaff Angela S, Deng Bo, Schwartz Ann G, Ryan Bríd |
| Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms. Human molecular genetics 2014 Jan 23 (2): 555-61. Bloom A Joseph, Baker Timothy B, Chen Li-Shiun, Breslau Naomi, Hatsukami Dorothy, Bierut Laura J, Goate Alis |
| CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Oct 34 (5): 2651-7. Liu Yu-liang, Xu Yu, Li Fan, Chen Hong, Guo Shu-lia |
| Cytochrome P450 2A6 deletion polymorphism and risk of lung cancer: a meta-analysis. Molecular biology reports 2013 Sep 40 (9): 5255-9. Liu Zheng-Bing, Shu Jun, Wang Li-Ping, Jin Cheng, Lou Zhi-X |
| CYP2A6, CYP1A1, and CYP2D6 polymorphisms in lung cancer patients from central south China. Medical oncology (Northwood, London, England) 2013 Jun 30 (2): 521. Huang Feng-mao, Chen Han-chun, Khan Md Asaduzzaman, Yang Fu-lan, Wan Xin-xing, Xu Ai-hua, Ou-yang Fang-dan, Zhang Dian-zhe |
| CYP2A6 genotype and smoking behavior in current smokers screened for lung cancer. Substance use & misuse 2013 May 48 (7): 490-4. Styn Mindi A, Nukui Tomoko, Romkes Marjorie, Perkins Kenneth A, Land Stephanie R, Weissfeld Joel |
| Association between CYP2A6 genetic polymorphisms and lung cancer: a meta-analysis of case-control studies. Environmental and molecular mutagenesis 2013 Mar 54 (2): 133-40. Liu Tao, Xie Chuan-Bo, Ma Wen-Jun, Chen Wei-Qi |
| Association of CYP2A6*4 with susceptibility of lung cancer: a meta-analysis. PloS one 2013 8 (4): e59556. Wang Lishan, Zang Weidong, Liu Jiang, Xie Dongli, Ji Weidong, Pan Yaosheng, Li Zhiqiang, Shen Jiawei, Shi Yongyo |
| Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. International journal of molecular sciences 2013 14 (4): 8381-92. Wassenaar Catherine A, Dong Qiong, Amos Christopher I, Spitz Margaret R, Tyndale Rachel |
| Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population. Clinica chimica acta; international journal of clinical chemistry 2012 Nov . Islam MS, Ahmed MU, Bin Sayeed MS, Al Maruf A, Mostofa AG, Akram Hussain SM, Kabir Y, Daly AK, Hasnat A |
| Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
PloS one 2012 7 (9): e44507. Kumasaka Natsuhiko, Aoki Masayuki, Okada Yukinori, Takahashi Atsushi, Ozaki Kouichi, Mushiroda Taisei, Hirota Tomomitsu, Tamari Mayumi, Tanaka Toshihiro, Nakamura Yusuke, Kamatani Naoyuki, Kubo Michia |
| Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. Journal of the National Cancer Institute 2011 Sep 103 (17): 1342-6. Wassenaar Catherine A, Dong Qiong, Wei Qingyi, Amos Christopher I, Spitz Margaret R, Tyndale Rachel |
| Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan. Drug metabolism and pharmacokinetics 2011 26 (5): 516-22. Tamaki Yuichiro, Arai Tomio, Sugimura Haruhiko, Sasaki Takamitsu, Honda Masashi, Muroi Yuka, Matsubara Yoichi, Kanno Shuichi, Ishikawa Masaaki, Hirasawa Noriyasu, Hiratsuka Masahi |
| Genomic copy number variations in three Southeast Asian populations. Human mutation 2010 Jul 31 (7): 851-7. Ku Chee-Seng, Pawitan Yudi, Sim Xueling, Ong Rick T H, Seielstad Mark, Lee Edmund J D, Teo Yik-Ying, Chia Kee-Seng, Salim Ag |
| Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
Nature genetics 2010 May 42 (5): 448-53. Thorgeirsson Thorgeir E, Gudbjartsson Daniel F, Surakka Ida, Vink Jacqueline M, Amin Najaf, Geller Frank, Sulem Patrick, Rafnar Thorunn, Esko Tõnu, Walter Stefan, Gieger Christian, Rawal Rajesh, Mangino Massimo, Prokopenko Inga, Mägi Reedik, Keskitalo Kaisu, Gudjonsdottir Iris H, Gretarsdottir Solveig, Stefansson Hreinn, Thompson John R, Aulchenko Yurii S, Nelis Mari, Aben Katja K, den Heijer Martin, Dirksen Asger, Ashraf Haseem, Soranzo Nicole, Valdes Ana M, Steves Claire, Uitterlinden André G, Hofman Albert, Tönjes Anke, Kovacs Peter, Hottenga Jouke Jan, Willemsen Gonneke, Vogelzangs Nicole, Döring Angela, Dahmen Norbert, Nitz Barbara, Pergadia Michele L, Saez Berta, De Diego Veronica, Lezcano Victoria, Garcia-Prats Maria D, Ripatti Samuli, Perola Markus, Kettunen Johannes, Hartikainen Anna-Liisa, Pouta Anneli, Laitinen Jaana, Isohanni Matti, Huei-Yi Shen, Allen Maxine, Krestyaninova Maria, Hall Alistair S, Jones Gregory T, van Rij Andre M, Mueller Thomas, Dieplinger Benjamin, Haltmayer Meinhard, Jonsson Steinn, Matthiasson Stefan E, Oskarsson Hogni, Tyrfingsson Thorarinn, Kiemeney Lambertus A, Mayordomo Jose I, Lindholt Jes S, Pedersen Jesper Holst, Franklin Wilbur A, Wolf Holly, Montgomery Grant W, Heath Andrew C, Martin Nicholas G, Madden Pamela A F, Giegling Ina, Rujescu Dan, Järvelin Marjo-Riitta, Salomaa Veikko, Stumvoll Michael, Spector Tim D, Wichmann H-Erich, Metspalu Andres, Samani Nilesh J, Penninx Brenda W, Oostra Ben A, Boomsma Dorret I, Tiemeier Henning, van Duijn Cornelia M, Kaprio Jaakko, Gulcher Jeffrey R, , McCarthy Mark I, Peltonen Leena, Thorsteinsdottir Unnur, Stefansson Ka |
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- Page last updated:Oct 20, 2021
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