HuGE Literature Finder
Records 1-30
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Impact of KRAS mutation subtype and concurrent pathogenic mutations on non-small cell lung cancer outcomes.
Lung cancer (Amsterdam, Netherlands) 2019 Jul 133 144-150. Aredo Jacqueline V, Padda Sukhmani K, Kunder Christian A, Han Summer S, Neal Joel W, Shrager Joseph B, Wakelee Heather |
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Mutation landscape and tumor mutation burden analysis of Chinese patients with pulmonary sarcomatoid carcinomas.
International journal of clinical oncology 2019 May . Liang Xiaohong, Li Qing, Xu Bin, Hu Song, Wang Qianyun, Li Yan, Zong Yun, Zhang Sujuan, Li Cho |
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Concurrent Driver Gene Mutations as Negative Predictive Factors in Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer.
EBioMedicine 2019 Mar . Chen Minjiang, Xu Yan, Zhao Jing, Zhong Wei, Zhang Li, Bi Yalan, Wang Mengzh |
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Prognostic Effect of TP53 and PKD Co-Mutations in Patients with Resected Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma.
Annals of surgical oncology 2019 Feb . Liu Di-Han, Zhao Ze-Rui, Lin Yao-Bin, Zhou Wen-Jie, Hou Jing-Yu, Ye Zheng-Hao, Long H |
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The prognostic impact of TP53 comutation in EGFR mutant lung cancer patients: a systematic review and meta-analysis.
Postgraduate medicine 2019 Feb . Zhang Rui, Tian Panwen, Chen Bojiang, Wang Tao, Li Weim |
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Concomitant resistance mechanisms to multiple tyrosine kinase inhibitors in ALK-positive non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2019 Jan 127 19-24. Yu Yongfeng, Ou Qiuxiang, Wu Xue, Bao Hairong, Ding Yan, Shao Yang W, Lu Sh |
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Oncogenic driver mutations in Swiss never smoker patients with lung adenocarcinoma and correlation with clinicopathologic characteristics and outcome.
PloS one 2019 14 (8): e0220691. Grosse Claudia, Soltermann Alex, Rechsteiner Markus, Grosse Alexand |
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Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing.
Cancer science 2018 Dec 109 (12): 3921-3933. Iwama Eiji, Sakai Kazuko, Azuma Koichi, Harada Daijiro, Nosaki Kaname, Hotta Katsuyuki, Nishio Makoto, Kurata Takayasu, Fukuhara Tatsuro, Akamatsu Hiroaki, Goto Koichi, Shimose Takayuki, Kishimoto Junji, Nakanishi Yoichi, Nishio Kazuto, Okamoto Isa |
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Frequency and clinical significance of NF1 mutation in lung adenocarcinomas from East Asian patients.
International journal of cancer 2018 Sep . Pan Yunjian, Yuan Chongze, Cheng Chao, Zhang Yiliang, Ma Yuan, Zheng Difan, Zheng Shanbo, Li Yuan, Jin Yan, Sun Yihua, Chen Haiqu |
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Identification of a highly lethal V3
International journal of cancer 2018 Sep . Christopoulos P, Kirchner M, Bozorgmehr F, Endris V, Elsayed M, Budczies J, Ristau J, Penzel R, Herth F J, Heussel C P, Eichhorn M, Muley T, Meister M, Fischer J R, Rieken S, Lasitschka F, Bischoff H, Sotillo R, Schirmacher P, Thomas M, Stenzinger |
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The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2018 Sep 123 22-29. Jao Kevin, Tomasini Pascale, Kamel-Reid Suzanne, Korpanty Gregorz J, Mascaux Céline, Sakashita Shingo, Labbé Catherine, Leighl Natasha B, Liu Geoffrey, Feld Ronald, Bradbury Penelope A, Hwang David M, Pintilie Melania, Tsao Ming-Sound, Shepherd Frances |
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The prognostic value of TP53 and its correlation with EGFR mutation in advanced non-small cell lung cancer, an analysis based on cBioPortal data base.
Lung cancer (Amsterdam, Netherlands) 2018 Sep 123 70-75. Jiao Xiao-Dong, Qin Bao-Dong, You Pu, Cai Jian, Zang Yuan-She |
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Contribution of smoking habit to the prognosis of stage I KRAS-mutated non-small cell lung cancer.
Cancer biomarkers : section A of Disease markers 2018 Aug . Kuroda Hiroaki, Yoshida Tatsuya, Arimura Takaaki, Mizuno Tetsuya, Sakakura Noriaki, Yatabe Yasushi, Sakao Yukino |
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Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Aug . Kron A, Alidousty C, Scheffler M, Merkelbach-Bruse S, Seidel D, Riedel R, Ihle M, Michels S, Nogova L, Fassunke J, Heydt C, Kron F, Ueckeroth F, Serke M, Krüger S, Grohe C, Koschel D, Benedikter J, Kaminsky B, Schaaf B, Braess J, Sebastian M, Kambartel K-O, Thomas R, Zander T, Schultheis A M, Büttner R, Wolf |
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Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2018 Aug JCO2018781963. Devarakonda Siddhartha, Rotolo Federico, Tsao Ming-Sound, Lanc Irena, Brambilla Elisabeth, Masood Ashiq, Olaussen Ken A, Fulton Robert, Sakashita Shingo, McLeer-Florin Anne, Ding Keyue, Le Teuff Gwénaël, Shepherd Frances A, Pignon Jean-Pierre, Graziano Stephen L, Kratzke Robert, Soria Jean-Charles, Seymour Lesley, Govindan Ramaswamy, Michiels Stef |
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Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance.
Lung cancer (Amsterdam, Netherlands) 2018 Jun 120 113-121. Du Meijun, Thompson Jonathan, Fisher Hannah, Zhang Peng, Huang Chiang-Ching, Wang Lia |
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Next?generation sequencing?based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her?2 and TP53 mutations in patients with non?small cell lung cancer.
Molecular medicine reports 2018 Jun . Jing Changwen, Mao Xuhua, Wang Zhuo, Sun Kejing, Ma Rong, Wu Jianzhong, Cao Haix |
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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
Cancer discovery 2018 May . Skoulidis Ferdinandos, Goldberg Michael E, Greenawalt Danielle M, Hellmann Matthew D, Awad Mark M, Gainor Justin F, Schrock Alexa B, Hartmaier Ryan J, Trabucco Sally E, Gay Laurie, Ali Siraj M, Elvin Julia A, Singal Gaurav, Ross Jeffrey S, Fabrizio David, Szabo Peter M, Chang Han, Sasson Ariella, Srinivasan Sujaya, Kirov Stefan, Szustakowski Joseph, Vitazka Patrik, Edwards Robin, Bufill Jose A, Sharma Neelesh, Ou Sai-Hong I, Peled Nir, Spigel David R, Rizvi Hira, Jimenez Aguilar Elizabeth, Carter Brett W, Erasmus Jeremy, Halpenny Darragh F, Plodkowski Andrew J, Long Niamh M, Nishino Mizuki, Denning Warren L, Galan-Cobo Ana, Hamdi Haifa, Hirz Taghreed, Tong Pan, Wang Jing, Rodriguez-Canales Jaime, Villalobos Pamela A, Parra Edwin R, Kalhor Neda, Sholl Lynette M, Sauter Jennifer L, Jungbluth Achim A, Mino-Kenudson Mari, Azimi Roxana, Elamin Yasir Y, Zhang Jianjun, Leonardi Giulia C, Jiang Fei, Wong Kwok-Kin, Lee J Jack, Papadimitrakopoulou Vassiliki A, Wistuba Ignacio I, Miller Vincent A, Frampton Garrett M, Wolchok Jedd D, Shaw Alice T, Jänne Pasi A, Stephens Philip J, Rudin Charles M, Geese William J, Albacker Lee A, Heymach John |
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Comprehensive Molecular Characterization of Young Chinese Patients with Lung Adenocarcinoma Identified a Distinctive Genetic Profile.
The oncologist 2018 Apr . Hou Helei, Zhu Hua, Zhao Han, Yan Weihua, Wang Yongjie, Jiang Man, Liu Bin, Liu Dong, Zhou Na, Zhang Chuantao, Li Pansong, Chang Lianpeng, Guan Yanfang, Wang Zhe, Zhang Xiaoping, Li Zhuokun, Fang Bingliang, Zhang Xiaoch |
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Frequency of MAP2K1, TP53, and U2AF1 Mutations in BRAF-mutated Langerhans Cell Histiocytosis: Further Characterizing the Genomic Landscape of LCH.
The American journal of surgical pathology 2018 Apr . McGinnis Lisa M, Nybakken Grant, Ma Lisa, Arber Daniel |
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Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Virchows Archiv : an international journal of pathology 2018 Apr . Wang Yajian, Liu Haijing, Hou Yingyong, Zhou Xiaoyan, Liang Li, Zhang Zhihong, Shi Huaiyin, Xu Sanpeng, Hu Peizhen, Zheng Zuyu, Liu Rui, Tang Tingdong, Ye Feng, Liang Zhiyong, Bu Ho |
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Response to crizotinib in advanced ALK-rearranged non-small cell lung cancers with different ALK-fusion variants.
Lung cancer (Amsterdam, Netherlands) 2018 Apr 118 128-133. Li Yan, Zhang Tongtong, Zhang Jing, Li Wenbin, Yuan Pei, Xing Puyuan, Zhang Zhou, Chuai Shannon, Li Junling, Ying Jianmi |
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Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma.
Journal of cancer research and clinical oncology 2018 Mar . Nakasone Shoko, Mimaki Sachiyo, Ichikawa Tomohiro, Aokage Keiju, Miyoshi Tomohiro, Sugano Masato, Kojima Motohiro, Fujii Satoshi, Kuwata Takeshi, Ochiai Atsushi, Tsuboi Masahiro, Goto Koichi, Tsuchihara Katsuya, Ishii Genichi |
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Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing.
Neoplasia (New York, N.Y.) 2018 Feb 20 (3): 256-262. Shajani-Yi Zahra, de Abreu Francine B, Peterson Jason D, Tsongalis Gregory |
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KRAS Mutation is Predictive of Outcome in Patients with Pulmonary Sarcomatoid Carcinoma.
Histopathology 2018 Feb . Mehrad Mitra, Roy Somak, LaFramboise William A, Petrosko Patti, Miller Caitlyn, Incharoen Pimpin, Dacic San |
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Unique Genetic Profiles from Cerebrospinal Fluid Cell-free DNA in Leptomeningeal Metastases of EGFR-mutant Non-Small Cell Lung Cancer: A New Medium of Liquid Biopsy.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Jan . Li Y S, Jiang B Y, Yang J J, Zhang X C, Zhang Z, Ye J Y, Zhong W Z, Tu H Y, Chen H J, Wang Z, Xu C R, Wang B C, Du H J, Chuai S, Han-Zhang H, Su J, Zhou Q, Yang X N, Guo W B, Yan H H, Liu Y H, Yan L X, Huang B, Zheng M M, Wu Y |
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About molecular profile of lung cancer in Tunisian patients.
Journal of immunoassay & immunochemistry 2018 39 (1): 99-107. Mezni Faouzi, Mlika Mona, Boussen Hamouda, Ghedira Habib, Fenniche Soraya, Faten Talmoudi, Loriot Marie-An |
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Clinicopathological and genomic comparisons between different histologic components in combined small cell lung cancer and non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2018 11 125 282-290. Lin Mong-Wei, Su Kang-Yi, Su Te-Jen, Chang Chia-Ching, Lin Jing-Wei, Lee Yi-Hsuan, Yu Sung-Liang, Chen Jin-Shing, Hsieh Min-S |
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Distribution of KRAS, DDR2, and TP53 gene mutations in lung cancer: An analysis of Iranian patients.
PloS one 2018 13 (7): e0200633. Fathi Zahra, Mousavi Seyed Ali Javad, Roudi Raheleh, Ghazi Farid |
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Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis.
Lung cancer (Amsterdam, Netherlands) 2018 12 126 182-188. Udagawa Hibiki, Umemura Shigeki, Murakami Isao, Mimaki Sachiyo, Makinoshima Hideki, Ishii Genichiro, Miyoshi Tomohiro, Kirita Keisuke, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Tsuchihara Katsuya, Goto Koic |
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Interaction analysis between germline susceptibility loci and somatic alterations in lung cancer.
International journal of cancer 2018 08 143 (4): 878-885. Wang Yuzhuo, Wang Cheng, Zhang Jiahui, Zhu Meng, Zhang Xu, Li Zhihua, Dai Juncheng, Ma Hongxia, Hu Zhibin, Jin Guangfu, Shen Hongbi |
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Mechanisms of primary resistance to EGFR targeted therapy in advanced lung adenocarcinomas.
Lung cancer (Amsterdam, Netherlands) 2018 10 124 110-116. Jin Ying, Shi Xun, Zhao Jun, He Qiong, Chen Ming, Yan Junrong, Ou Qiuxiang, Wu Xue, Shao Yang W, Yu Xinm |
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Three new disease-progression modes in NSCLC patients after EGFR-TKI treatment by next-generation sequencing analysis.
Lung cancer (Amsterdam, Netherlands) 2018 11 125 43-50. Wei Yuqing, Shen Kaikai, Lv Tangfeng, Wang Xianghai, Li Chuling, Fan Hang, Lv Yanling, Liu Hongbing, Song Yo |
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Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients.
Cancer science 2017 Dec 108 (12): 2487-2494. Liu Liping, Liu Jilong, Shao Di, Deng Qiuhua, Tang Hailing, Liu Zu, Chen Xuewei, Guo Fengming, Lin Yongping, Mao Mao, Kristiansen Karsten, Ye Mingzhi, He Jianxi |
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NKX2-1 expression as a prognostic marker in early-stage non-small-cell lung cancer.
BMC pulmonary medicine 2017 Dec 17 (1): 197. Moisés Jorge, Navarro Alfons, Santasusagna Sandra, Viñolas Nuria, Molins Laureano, Ramirez José, Osorio Jeisson, Saco Adela, Castellano Joan Josep, Muñoz Carmen, Morales Sara, Monzó Mariano, Marrades Ramón Mar |
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The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2).
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Dec . Aisner Dara L, Sholl Lynette M, Berry Lynne, Rossi Michael, Chen Heidi, Fujimoto Junya, Moreira Andre L, Ramalingam Suresh, Villaruz Liza C, Otterson Gregory A, Haura Eric B, Politi Katerina, Glisson Bonnie S, Cetnar Jeremy, Garon Edward, Schiller Joan, Waqar Saiama, Sequist Lecia V, Brahmer Julie R, Shyr Yu, Kugler Kelly, Wistuba Ignacio Ivan, Johnson Bruce E, Minna John D, Kris Mark G, Bunn Paul A, Kwiatkowski David |
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Coexistent genetic alterations involving ALK, RET, ROS1 or MET in 15 cases of lung adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Sep . Tang Zhenya, Zhang Jianjun, Lu Xinyan, Wang Wei, Chen Hui, Robinson Melissa K, Cheng Joanne, Tang Guilin, Medeiros L Jeffr |
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Genomic Profiles of Lung Cancer Associated with Idiopathic Pulmonary Fibrosis.
The Journal of pathology 2017 Sep . Hwang Ji An, Kim Deokhoon, Chun Sung-Min, Bae SooHyun, Song Joon Seon, Kim Mi Young, Koo Hyun Jung, Song Jin Woo, Kim Woo Sung, Lee Jae Cheol, Kim Hyeong Ryul, Choi Chang-Min, Jang Se J |
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Prognostic and predictive effects of TP53 co-mutation in patients with EGFR-mutated non-small cell lung cancer (NSCLC).
Lung cancer (Amsterdam, Netherlands) 2017 Sep 111 23-29. Labbé Catherine, Cabanero Michael, Korpanty Grzegorz J, Tomasini Pascale, Doherty Mark K, Mascaux Céline, Jao Kevin, Pitcher Bethany, Wang Rick, Pintilie Melania, Leighl Natasha B, Feld Ronald, Liu Geoffrey, Bradbury Penelope Ann, Kamel-Reid Suzanne, Tsao Ming-Sound, Shepherd Frances |
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Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small lung cancer (NSCLC) patients.
Carcinogenesis 2017 Aug . Couto Patrícia P, Bastos-Rodrigues Luciana, Schayek Hagit, Melo Flavia M, Lisboa Raony G C, Miranda Debora M, Vilhena Alyne, Bale Allen E, Friedman Eitan, De Marco Lu |
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Targeted next-generation sequencing for analyzing the genetic alterations in atypical adenomatous hyperplasia and adenocarcinoma in situ.
Journal of cancer research and clinical oncology 2017 Aug . Xu Xuan, Li Na, Zhao Ruiying, Zhu Lei, Shao Jinchen, Zhang J |
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Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes.
Lung cancer (Amsterdam, Netherlands) 2017 Apr 106 17-21. VanderLaan Paul A, Rangachari Deepa, Mockus Susan M, Spotlow Vanessa, Reddi Honey V, Malcolm Joan, Huberman Mark S, Joseph Loren J, Kobayashi Susumu S, Costa Daniel |
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Xenobiotic/drug metabolizing enzyme and TP53 polymorphisms and clinical outcome in advanced nonsmall cell lung cancer patients.
Turkish journal of medical sciences 2017 Apr 47 (2): 554-562. Karacao?lan Volkan, Ada Ahmet O?uz, Bilgen Serdar, Çetinkaya Guzide Tu?ba, Soyda? Emre, Kunak Celalettin Semih, Alpar Sibel Meryem, Gülhan Meral, I?can Mümt |
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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.
European journal of cancer (Oxford, England : 1990) 2017 Mar 76 144-151. de Jonge Maja, de Weger Vincent A, Dickson Mark A, Langenberg Marlies, Le Cesne Axel, Wagner Andrew J, Hsu Karl, Zheng Wei, Macé Sandrine, Tuffal Gilles, Thomas Koruth, Schellens Jan H |
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p53 signaling pathway polymorphisms associated with emphysematous changes in COPD patients.
Chest 2017 Mar . Mizuno Shiro, Ishizaki Takeshi, Kadowaki Maiko, Akai Masaya, Shiozaki Kohei, Iguchi Masaharu, Oikawa Taku, Nakagawa Ken, Osanai Kazuhiro, Toga Hirohisa, Gomez-Arroyo Jose, Kraskauskas Donatas, Cool Carlyne D, Bogaard Herman J, Voelkel Norbert |
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Oral mucosa and lung cancer: Are genetic changes in the oral epithelium associated with lung cancer?
Nigerian journal of clinical practice 2017 Jan 20 (1): 12-18. Kömerik N, Yüce E, Calapo?lu N S, Ko?ar P A, Çakir M, Koparan |
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P73 G4C14-to-A4T14 polymorphism is associated with survival in advanced non-small cell lung cancer patients.
Thoracic cancer 2017 Jan . Ge Lei, Yang Yang, Sun Yifeng, Xu Wen, Lu Daru, Su |
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Clinical Significance of DNA Damage Response Factors and Chromosomal Instability in Primary Lung Adenocarcinoma.
Anticancer research 2017 04 37 (4): 1729-1735. Okamoto Tatsuro, Kohno Mikihiro, Ito Kensaku, Takada Kazuki, Katsura Masakazu, Morodomi Yosuke, Toyokawa Gouji, Shoji Fumihiro, Maehara Yoshihi |
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Computer-Aided Nodule Assessment and Risk Yield (CANARY) may facilitate non-invasive prediction of EGFR mutation status in lung adenocarcinomas.
Scientific reports 2017 12 7 (1): 17620. Clay Ryan, Kipp Benjamin R, Jenkins Sarah, Karwoski Ron A, Maldonado Fabien, Rajagopalan Srinivasan, Voss Jesse S, Bartholmai Brian J, Aubry Marie Christine, Peikert Tobi |
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Genetic polymorphisms and lung cancer risk: Evidence from meta-analyses and genome-wide association studies.
Lung cancer (Amsterdam, Netherlands) 2017 11 113 18-29. Liu Caiyang, Cui Huijie, Gu Dongqing, Zhang Min, Fang Yanfei, Chen Siyu, Tang Mingshuang, Zhang Ben, Chen Huanw |
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Germline Mutations in DNA Repair Genes in Lung Adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2017 11 12 (11): 1673-1678. Parry Erin M, Gable Dustin L, Stanley Susan E, Khalil Sara E, Antonescu Valentin, Florea Liliana, Armanios Ma |
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Next-generation sequencing of Chinese stage IV lung cancer patients reveals an association between EGFR mutation status and survival outcome.
Clinical genetics 2017 03 91 (3): 488-493. Li F, Du X, Zhang H, Ju T, Chen C, Qu Q, Zhang X, Qi L, Lizée |
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Somatic Mutations and Ancestry Markers in Hispanic Lung Cancer Patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2017 12 12 (12): 1851-1856. Gimbrone Nicholas T, Sarcar Bhaswati, Gordian Edna R, Rivera Jason I, Lopez Christian, Yoder Sean J, Teer Jamie K, Welsh Eric A, Chiappori Alberto A, Schabath Matthew B, Reuther Gary W, Dutil Julie, Garcia Miosotis, Ventosilla-Villanueva Ronald, Vera-Valdivia Luis, Yabar-Berrocal Alejandro, Motta-Guerrero Rodrigo, Santiago-Cardona Pedro G, Muñoz-Antonia Teresita, Cress W Dougl |
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Association between the TP53 and CYP2E1*5B gene polymorphisms and non-small cell lung cancer.
Arhiv za higijenu rada i toksikologiju 2016 Dec 67 (4): 311-316. Ada Ahmet Oguz, Bilgen Serdar, Karacaoglan Volkan, Kunak Celalettin Semih, Soydas Emre, Alpar Sibel, Gulhan Meral, Iscan Mumt |
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The MDM2 T309G polymorphism and risk of lung cancer: an updated meta-analysis of 10,186 cases and 14,155 controls.
Panminerva medica 2016 Dec 58 (4): 341-348. Tian Xiaodong, Wang Bo, Guo Juntang, Liu Xi, Zhang Tao, Liang Chaoyang, Zhou Naikang, Hou Xiaobin, Ma Yongfu, Yu Hua, Chen Lei, Ren Zhipeng, Fan Kaijie, Tian Qi |
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A phase II open-label multicenter study of gefitinib in combination with irradiation followed by chemotherapy in patients with inoperable stage III non-small cell lung cancer.
Oncotarget 2016 Oct . Levy Antonin, Bardet Etienne, Lacas Benjamin, Pignon Jean-Pierre, Adam Julien, Lacroix Ludovic, Artignan Xavier, Verrelle Pierre, Le Péchoux Céci |
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CCSP G38A polymorphism environment interactions regulate CCSP levels differentially in COPD.
American journal of physiology. Lung cellular and molecular physiology 2016 Oct 311 (4): L696-L703. Knabe Lucie, Varilh Jessica, Bergougnoux Anne, Gamez Anne-Sophie, Bonini Jennifer, Pommier Alexandra, Petit Aurélie, Molinari Nicolas, Vachier Isabelle, Taulan-Cadars Magali, Bourdin Arna |
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Impact of TP53 Mutations on Outcome in EGFR-Mutated Patients Treated with First-Line Tyrosine Kinase Inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Oct . Canale Matteo, Petracci Elisabetta, Delmonte Angelo, Chiadini Elisa, Dazzi Claudio, Papi Maximilian, Capelli Laura, Casanova Claudia, De Luigi Nicoletta, Mariotti Marita, Gamboni Alessandro, Chiari Rita, Bennati Chiara, Calistri Daniele, Ludovini Vienna, Crinò Lucio, Amadori Dino, Ulivi Pao |
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Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Molecular cancer 2016 Oct 15 (1): 63. Kovaleva Valentina, Geissler Anna-Lena, Lutz Lisa, Fritsch Ralph, Makowiec Frank, Wiesemann Sebastian, Hopt Ulrich T, Passlick Bernward, Werner Martin, Lassmann Sil |
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Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy.
Molecular biology reports 2016 Sep . Kumari Ankita, Bahl Charu, Singh Navneet, Behera Digambar, Sharma Siddhar |
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Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer.
Oncotarget 2016 Sep . Villaflor Victoria, Won Brian, Nagy Rebecca, Banks Kimberly, Lanman Richard B, Talasaz AmirAli, Salgia Ra |
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Hot spot mutations in Finnish non-small cell lung cancers.
Lung cancer (Amsterdam, Netherlands) 2016 Sep 99 102-10. Mäki-Nevala Satu, Sarhadi Virinder Kaur, Rönty Mikko, Kettunen Eeva, Husgafvel-Pursiainen Kirsti, Wolff Henrik, Knuuttila Aija, Knuutila Saka |
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Metabolism Differs in PDAC and NSCLC with the Same Genetic Background.
Cancer discovery 2016 Sep . Authors are not available |
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Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer.
Oncotarget 2016 Sep 7 (38): 61575-61586. van Ginkel Joost H, de Leng Wendy W J, de Bree Remco, van Es Robert J J, Willems Stefan |
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Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up.
Annals of oncology : official journal of the European Society for Medical Oncology 2016 Sep . Kadara H, Choi M, Zhang J, Cuentas E P, Canales J R, Gaffney S G, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons D L, Heymach J, Kaftan E, Townsend J P, Lynch T J, Schlessinger J, Lee J, Lifton R P, Wistuba I I, Herbst R |
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Genomic profiling of large-cell neuroendocrine carcinoma of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Aug . Miyoshi Tomohiro, Umemura Shigeki, Matsumura Yuki, Mimaki Sachiyo, Tada Satoshi, Ishii Genichiro, Udagawa Hibiki, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Ohmatsu Hironobu, Aokage Keiju, Hishida Tomoyuki, Yoshida Junji, Nagai Kanji, Goto Koichi, Tsuboi Masahiro, Tsuchihara Katsu |
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HER2 mutations in Chinese patients with non-small cell lung cancer.
Oncotarget 2016 Aug . Song Zhengbo, Yu Xinmin, Shi Zhiyong, Zhao Jun, Zhang Yipi |
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Tumor volume determines the feasibility of cell-free DNA sequencing for mutation detection in non-small cell lung cancer.
Cancer science 2016 Aug . Ohira Tatsuo, Sakai Kazuko, Matsubayashi Jun, Kajiwara Naohiro, Kakihana Masatoshi, Hagiwara Masaru, Hibi Masaaki, Yoshida Koichi, Maeda Junichi, Ohtani Keishi, Nagao Toshitaka, Nishio Kazuto, Ikeda Norihi |
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Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology.
Oncotarget 2016 Jul . Zhang Shirong, Xia Bing, Jiang Hong, Wang Limin, Xu Rujun, Shi Yanbin, Zhang Jianguang, Xu Mengnan, Cram David S, Ma Shengl |
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Intra-tumoral Immune Cell Densities are Associated with Lung Adenocarcinoma Gene Alterations.
American journal of respiratory and critical care medicine 2016 Jun . Mansuet-Lupo Audrey, Alifano Marco, Pécuchet Nicolas, Biton Jérôme, Becht Etienne, Goc Jeremy, Germain Claire, Ouakrim Hanane, Régnard Jean-François, Cremer Isabelle, Laurent-Puig Pierre, Dieu-Nosjean Marie-Caroline, Blons Hélène, Damotte Dia |
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Morphological and genetic heterogeneity in multifocal lung adenocarcinoma: The case of a never-smoker woman.
Lung cancer (Amsterdam, Netherlands) 2016 Jun 96 52-5. Bonanno Laura, Calabrese Fiorella, Nardo Giorgia, Calistri Daniele, Tebaldi Michela, Tedaldi Gianluca, Polo Valentina, Vuljan Stefania, Favaretto Adolfo, Conte PierFranco, Amadori Alberto, Rea Federico, Indraccolo Stefa |
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USP7 inhibitors, downregulating CCDC6, sensitize lung neuroendocrine cancer cells to PARP-inhibitor drugs.
Lung cancer (Amsterdam, Netherlands) 2016 Jun . Malapelle Umberto, Morra Francesco, Ilardi Gennaro, Visconti Roberta, Merolla Francesco, Cerrato Aniello, Napolitano Virginia, Monaco Roberto, Guggino Gianluca, Monaco Guglielmo, Staibano Stefania, Troncone Giancarlo, Celetti Ange |
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KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients.
Molecular carcinogenesis 2016 May . Gao Weimin, Jin Jide, Yin Jinling, Land Stephanie, Gaither-Davis Autumn, Christie Neil, Luketich James D, Siegfried Jill M, Keohavong Phoutho |
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Precision medicine in age-specific non-small-cell-lung-cancer patients: Integrating biomolecular results into clinical practice-A new approach to improve personalized translational research.
Lung cancer (Amsterdam, Netherlands) 2016 May . Vavalà Tiziana, Monica Valentina, Lo Iacono Marco, Mele Teresa, Busso Simone, Righi Luisella, Papotti Mauro, Scagliotti Giorgio Vittorio, Novello Silv |
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Prognostic potential of the MDM2 309T>G polymorphism in stage I lung adenocarcinoma.
Cancer medicine 2016 May . Enokida Yasuaki, Shimizu Kimihiro, Atsumi Jun, Kakegawa Seiichi, Takase Yoshiaki, Kaira Kyoichi, Yashima Hideaki, Araki Takuya, Nakazawa Seshiru, Ohtaki Yoichi, Nagashima Toshiteru, Alexander Lezhava, Usui Kengo, Ishikawa Toshihisa, Hayashizaki Yoshihide, Takeyoshi Izu |
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Clinical correlation of extensive-stage small-cell lung cancer genomics.
Annals of oncology : official journal of the European Society for Medical Oncology 2016 Apr 27 (4): 642-7. Dowlati A, Lipka M B, McColl K, Dabir S, Behtaj M, Kresak A, Miron A, Yang M, Sharma N, Fu P, Wildey |
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Elevated integrin ?6?4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer.
Human pathology 2016 Apr . Stewart Rachel L, West Dava, Wang Chi, Weiss Heidi L, Gal Tamas, Durbin Eric, O'Connor William, Chen Min, O'Connor Kathleen |
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Targeted sequencing identifies genetic alterations that confer Primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium).
Oncotarget 2016 Apr . Lim Sun Min, Kim Hye Ryun, Cho Eun Kyung, Min Young Joo, Ahn Jin Seok, Ahn Myung-Ju, Park Keunchil, Cho Byoung Chul, Lee Ji-Hyun, Jeong Hye Cheol, Kim Eun Kyung, Kim Joo-Ha |
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Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative.
Oncotarget 2016 Mar . Lim Sun Min, Kim Eun Young, Kim Hye Ryun, Ali Siraj M, Greenbowe Joel R, Shim Hyo Sup, Chang Hyun, Lim Seungtaek, Paik Soonmyung, Cho Byoung Ch |
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Clinical and molecular characteristics of NF1 mutant lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb . Redig Amanda J, Capelletti Marzia, Dahlberg Suzanne E, Sholl Lynette M, Mach Stacy L, Fontes Caitlin, Shi Yunling, Chalasani Poornima, Janne Pasi |
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Prognostic and predictive effect of TP53 mutations in non-small cell lung cancer patients from adjuvant cisplatin-based therapy randomized trials: a LACE-bio pooled analysis.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Feb . Ma Xiaoli, Le Teuff Gwénaël, Lacas Benjamin, Tsao Ming Sound, Graziano Stephen, Pignon Jean-Pierre, Douillard Jean-Yves, Le Chevalier Thierry, Seymour Lesley, Filipits Martin, Pirker Robert, Janne Pasi, Shepherd Frances A, Brambilla Elisabeth, Soria Jean-Charles, Hainaut Pierre, |
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Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors.
Cancer genetics 2016 Jan . Mukherjee S, Ma Z, Wheeler S, Sathanoori M, Coldren C, Prescott J L, Kozyr N, Bouzyk M, Correll M, Ho H, Chandra P K, Lennon P |
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Clinical Validation and Implementation of a Targeted Next-Generation Sequencing Assay to Detect Somatic Variants in Non-Small Cell Lung, Melanoma, and Gastrointestinal Malignancies.
The Journal of molecular diagnostics : JMD 2016 Jan . Fisher Kevin E, Zhang Linsheng, Wang Jason, Smith Geoffrey H, Newman Scott, Schneider Thomas M, Pillai Rathi N, Kudchadkar Ragini R, Owonikoko Taofeek K, Ramalingam Suresh S, Lawson David H, Delman Keith A, El-Rayes Bassel F, Wilson Malania M, Sullivan H Clifford, Morrison Annie S, Balci Serdar, Adsay N Volkan, Gal Anthony A, Sica Gabriel L, Saxe Debra F, Mann Karen P, Hill Charles E, Khuri Fadlo R, Rossi Michael |
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Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Jan 11 (1): 122-7. Michels Sebastian, Scheel Andreas Hans, Scheffler Matthias, Schultheis Anne Maria, Gautschi Oliver, Aebersold Franziska, Diebold Joachim, Pall Georg, Rothschild Sacha, Bubendorf Lukas, Hartmann Wolfgang, Heukamp Lukas, Schildhaus Hans-Ulrich, Fassunke Jana, Ihle Michaela Angelika, Künstlinger Helen, Heydt Carina, Fischer Rieke, Nogovà Lucia, Mattonet Christian, Hein Rebecca, Adams Anne, Gerigk Ulrich, Schulte Wolfgang, Lüders Heike, Grohé Christian, Graeven Ullrich, Müller-Naendrup Clemens, Draube Andreas, Kambartel Karl-Otto, Krüger Stefan, Schulze-Olden Susanne, Serke Monika, Engel-Riedel Walburga, Kaminsky Britta, Randerath Winfried, Merkelbach-Bruse Sabine, Büttner Reinhard, Wolf Jürg |
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KRAS and NKX2-1 mutations in invasive mucinous adenocarcinoma of the lung.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Jan . Hwang David H, Sholl Lynette M, Rojas-Rudilla Vanesa, Hall Dimity L, Shivdasani Priyanka, Garcia Elizabeth P, MacConaill Laura E, Vivero Marina, Hornick Jason L, Kuo Frank C, Lindeman Neal I, Dong F |
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Association of P53 codon 72 polymorphism and lung cancer in an ethnic Iranian population.
Cellular and molecular biology (Noisy-le-Grand, France) 2016 62 (9): 34-8. Eydian Z, Asna'ashari A M H, Behravan J, Sharifi-Rad J, Entezari Heravi |
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Association of Single Nucleotide Polymorphisms in the Apoptosis-Related Genes TP63 and CD40 with Risk for Lung Cancer in a Chinese Han Population.
The Tohoku journal of experimental medicine 2016 238 (4): 279-86. Tang WenJun, Xue Li, Yan QiXing, Cai ShaoXi, Bai YuJie, Lin Li, Lin BiLin, Huang MingLong, Yi GuoHui, Li H |
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Circulating Tumor DNA Detection in Early-Stage Non-Small Cell Lung Cancer Patients by Targeted Sequencing.
Scientific reports 2016 08 6 31985. Chen Ke-Zhong, Lou Feng, Yang Fan, Zhang Jing-Bo, Ye Hua, Chen Wei, Guan Tian, Zhao Ming-Yu, Su Xue-Xia, Shi Rong, Jones Lindsey, Huang Xue F, Chen Si-Yi, Wang J |
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Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations.
PloS one 2016 11 (7): e0159094. Zonta Eleonora, Garlan Fanny, Pécuchet Nicolas, Perez-Toralla Karla, Caen Ouriel, Milbury Coren, Didelot Audrey, Fabre Elizabeth, Blons Hélène, Laurent-Puig Pierre, Taly Valér |
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Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.
BMC cancer 2016 16 (1): 28. Samulin Erdem Johanna, Skaug Vidar, Bakke Per, Gulsvik Amund, Haugen Aage, Zienolddiny Shanb |
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Prospective Analysis of Oncogenic Driver Mutations and Environmental Factors: Japan Molecular Epidemiology for Lung Cancer Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016 07 34 (19): 2247-57. Kawaguchi Tomoya, Koh Yasuhiro, Ando Masahiko, Ito Norimasa, Takeo Sadanori, Adachi Hirofumi, Tagawa Tsutomu, Kakegawa Seiichi, Yamashita Motohiro, Kataoka Kazuhiko, Ichinose Yukito, Takeuchi Yukiyasu, Serizawa Masakuni, Tamiya Akihiro, Shimizu Shigeki, Yoshimoto Naoki, Kubo Akihito, Isa Shun-Ichi, Saka Hideo, Matsumura Akihi |
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Complex analysis of the p53 tumor suppressor in lung carcinoma.
Oncology reports 2015 Dec . Smardova Jana, Liskova Kvetoslava, Ravcukova Barbora, Malcikova Jitka, Hausnerova Jitka, Svitakova Miluse, Hrabalkova Renata, Zlamalikova Lenka, Stano-Kozubik Katerina, Blahakova Ivona, Speldova Jana, Jarkovsky Jiri, Smarda J |
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Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis.
Molecular oncology 2015 Nov . Bjaanæs Maria Moksnes, Fleischer Thomas, Halvorsen Ann Rita, Daunay Antoine, Busato Florence, Solberg Steinar, Jørgensen Lars, Kure Elin, Edvardsen Hege, Børresen-Dale Anne-Lise, Brustugun Odd Terje, Tost Jörg, Kristensen Vessela, Helland Åsla |
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Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma.
Oncogene 2015 Oct . Schabath M B, Welsh E A, Fulp W J, Chen L, Teer J K, Thompson Z J, Engel B E, Xie M, Berglund A E, Creelan B C, Antonia S J, Gray J E, Eschrich S A, Chen D-T, Cress W D, Haura E B, Beg A |
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MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.
Cancer medicine 2015 Oct . Gansmo Liv B, Romundstad Pål, Birkeland Einar, Hveem Kristian, Vatten Lars, Knappskog Stian, Lønning Per Eyste |
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Association of p53 and mdm2 in the development and progression of non-small cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jul 36 (7): 5425-32. Javid Jamsheed, Mir Rashid, Julka P K, Ray P C, Saxena Alpa |
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Next-Generation Sequencing of Pulmonary Sarcomatoid Carcinoma Reveals High Frequency of Actionable MET Gene Mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Jul . Liu Xuewen, Jia Yuxia, Stoopler Mark B, Shen Yufeng, Cheng Haiying, Chen Jinli, Mansukhani Mahesh, Koul Sanjay, Halmos Balazs, Borczuk Alain |
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Prognostic value of ERCC1, ERCC2, XRCC1, and TP53 single nucleotide polymorphisms in patients with early-stage non-small cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jun 36 (6): 4279-85. Geredeli Caglayan, Artac Mehmet, Yildirim Selman, Inal Ali, Dede Isa, Guler Tunc, Boruban Melih Cem, Koral Lokman, Karaagac Mustafa, Zamani Ayse Gul, Altinok Tamer, Aribas Olgun, Bozcuk Hakan, Demirkazik Ahm |
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Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma.
Oncotarget 2015 May 6 (14): 12783-95. Bria Emilio, Pilotto Sara, Amato Eliana, Fassan Matteo, Novello Silvia, Peretti Umberto, Vavalà Tiziana, Kinspergher Stefania, Righi Luisella, Santo Antonio, Brunelli Matteo, Corbo Vincenzo, Giglioli Eliana, Sperduti Isabella, Milella Michele, Chilosi Marco, Scarpa Aldo, Tortora Giampao |
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Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
British journal of cancer 2015 Mar 112 (6): 1114-20. Zajkowicz A, Butkiewicz D, Drosik A, Giglok M, Suwi?ski R, Rusin |
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