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| Impact of Venetoclax and Azacitidine in Treatment-Naïve Patients with Acute Myeloid Leukemia and IDH1/2 Mutations. Clinical cancer research : an official journal of the American Association for Cancer Research 2022 1 28 (13): 2753-2761. Pollyea Daniel A, DiNardo Courtney D, Arellano Martha L, Pigneux Arnaud, Fiedler Walter, Konopleva Marina, Rizzieri David A, Smith B Douglas, Shinagawa Atsushi, Lemoli Roberto M, Dail Monique, Duan Yinghui, Chyla Brenda, Potluri Jalaja, Miller Catherine L, Kantarjian Hagop |
| Next-generation sequencing reveals gene mutations landscape and clonal evolution in patients with acute myeloid leukemia. Hematology (Amsterdam, Netherlands) 2021 (1): 111-122. Chen Xiao, Zhu Han, Qiao Chun, Zhao Sishu, Liu Lu, Wang Yan, Jin Huimin, Qian Sixuan, Wu Yuj |
| Quantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations. Leukemia & lymphoma 2021 5 62 (11): 2716-2726. Soare Dan-Sebastian, Radu Eugen, Dumitru Ion, Vl?d?reanu Ana Maria, Bumbea Hor |
| NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients. Asian Pacific journal of cancer prevention : APJCP 2020 7 21 (7): 1987-1992. Aref Salah, Rizk Rasha, El Agder Mohamed, Fakhry Wafaa, El Zafarany Maha, Sabry Moham |
| Prognostic relevance of a blastic plasmacytoid dendritic cell neoplasm-like immunophenotype in cytogenetically normal acute myeloid leukemia patients. Leukemia & lymphoma 2020 3 61 (7): 1695-1701. Guolo Fabio, Minetto Paola, Clavio Marino, Marcolin Riccardo, Miglino Maurizio, Passannante Monica, Caviglia Fabrizio, Ballerini Filippo, Tedone Elisabetta, Kunkl Annalisa, Mangerini Rosa, Contini Paola, Colombo Nicoletta, Cagnetta Antonia, Cea Michele, Carminati Enrico, Pugliese Girolamo, Gobbi Marco, Lemoli Roberto Massi |
| Bendamustine alone or with rituximab modifies expression of apoptosis-regulating genes and proteins of CLL cells, depending on IGVH mutational status. Leukemia & lymphoma 2018 9 60 (6): 1409-1419. Ziolkowska Ewelina, Wolowiec Dariusz, Karpinski Pawel, Blonski Jerzy Z, Lech-Maranda Ewa, Borowiec Maciej, Balcerczak Ewa, Sasiadek Maria, Robak Tadeusz, Korycka-Wolowiec An |
| Prognostic impact of low allelic ratio FLT3-ITD and NPM1 mutation in acute myeloid leukemia. Blood advances 2018 10 2 (20): 2744-2754. Sakaguchi Masahiro, Yamaguchi Hiroki, Najima Yuho, Usuki Kensuke, Ueki Toshimitsu, Oh Iekuni, Mori Sinichiro, Kawata Eri, Uoshima Nobuhiko, Kobayashi Yutaka, Kako Shinichi, Tajika Kenji, Gomi Seiji, Shono Katsuhiro, Kayamori Kensuke, Hagihara Masao, Kanda Junya, Uchiyama Hitoji, Kuroda Junya, Uchida Naoyuki, Kubota Yasushi, Kimura Shinya, Kurosawa Saiko, Nakajima Nana, Marumo Atsushi, Omori Ikuko, Fujiwara Yusuke, Yui Shunsuke, Wakita Satoshi, Arai Kunihito, Kitano Tomoaki, Kakihana Kazuhiko, Kanda Yoshinobu, Ohashi Kazuteru, Fukuda Takahiro, Inokuchi Koi |
| Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation. Journal of the National Comprehensive Cancer Network : JNCCN 2017 Jun 15 (6): 790-796. Hidalgo-López Juliana E, Kanagal-Shamanna Rashmi, Medeiros L Jeffrey, Estrov Zeev, Yin C Cameron, Verstovsek Srdan, Konoplev Sergej, Jorgensen Jeffrey L, Mohammad Mohammad M, Miranda Roberto N, Zhao Chong, Lee John, Zuo Zhuang, Bueso-Ramos Carlos |
| Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia. Oncotarget 2017 Feb . Ouyang Yuan, Qiao Chun, Chen Yu, Zhang Su-Jia |
| Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia. Leukemia 2015 Nov . Balss J, Thiede C, Bochtler T, Okun J G, Saadati M, Benner A, Pusch S, Ehninger G, Schaich M, Ho A D, von Deimling A, Krämer A, Heilig C |
| [IDH1 Gene Mutation and Its Clinical Significance in patients with Acute Myeloid Leukemia]. Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2015 Oct 23 (5): 1252-7. Wei Ji-Feng, Qiu Hui-Ying, Chen Guang-Hua, Wang Ying, Chen Zhe, Liu Hui-Jie, Mao Jian-Ping, Jia Tao, Xue Lian-Guo, Cai Zhi-Mei, Zhu Yuan-Xin, Zhao Li-Do |
| Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation. Blood 2015 Sep . Schmid Christoph, Labopin Myriam, Socié Gerard, Daguindau Etienne, Volin Liisa, Huynh Anne, Bourhis Jean Henri, Milpied Noel, Cornelissen Jan, Chevallier Patrice, Maertens Johan, Jindra Pavel, Blaise Didier, Lenhoff Stig, Ifrah Norbert, Baron Frédéric, Ciceri Fabio, Gorin Claude, Savani Bipin, Giebel Sebastian, Polge Emmanuelle, Esteve Jordi, Nagler Arnon, Mohty Moham |
| Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations. American journal of hematology 2015 Jul . Xu Yang, Sun Yanjun, Shen Hongjie, Ding Lin, Yang Zhen, Qiu Huiying, Sun Aining, Chen Suning, Wu Dep |
| DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2015 Jul . Ahn Jae-Sook, Kim Hyeoung-Joon, Kim Yeo-Kyeoung, Lee Seun-Shin, Jung Sung-Hoon, Yang Deok-Hwan, Lee Je-Jung, Kim Nan Young, Choi Seung Hyun, Jung Chul Won, Jang Jun-Ho, Kim Hee Je, Moon Joon Ho, Sohn Sang Kyun, Won Jong-Ho, Kim Sung-Hyun, Kim Dennis Dong Hw |
| Simpson's Paradox and the Impact of Different DNMT3A Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Jun 33 (18): 2072-83. Gale Rosemary E, Lamb Katarina, Allen Christopher, El-Sharkawi Dima, Stowe Cassandra, Jenkinson Sarah, Tinsley Steven, Dickson Glenda, Burnett Alan K, Hills Robert K, Linch David |
| WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups. Leukemia 2015 Mar 29 (3): 660-7. Krauth M-T, Alpermann T, Bacher U, Eder C, Dicker F, Ulke M, Kuznia S, Nadarajah N, Kern W, Haferlach C, Haferlach T, Schnittger |
| Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia: results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Feb 33 (5): 403-10. Röllig Christoph, Bornhäuser Martin, Kramer Michael, Thiede Christian, Ho Anthony D, Krämer Alwin, Schäfer-Eckart Kerstin, Wandt Hannes, Hänel Mathias, Einsele Hermann, Aulitzky Walter E, Schmitz Norbert, Berdel Wolfgang E, Stelljes Matthias, Müller-Tidow Carsten, Krug Utz, Platzbecker Uwe, Wermke Martin, Baldus Claudia D, Krause Stefan W, Stölzel Friedrich, von Bonin Malte, Schaich Markus, Serve Hubert, Schetelig Johannes, Ehninger Gerha |
| GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution. Annals of hematology 2015 Feb 94 (2): 211-21. Hou Hsin-An, Lin Yun-Chu, Kuo Yuan-Yeh, Chou Wen-Chien, Lin Chien-Chin, Liu Chieh-Yu, Chen Chien-Yuan, Lin Liang-In, Tseng Mei-Hsuan, Huang Chi-Fei, Chiang Ying-Chieh, Liu Ming-Chih, Liu Chia-Wen, Tang Jih-Luh, Yao Ming, Huang Shang-Yi, Ko Bor-Sheng, Hsu Szu-Chun, Wu Shang-Ju, Tsay Woei, Chen Yao-Chang, Tien Hwei-Fa |
| Quantitative detection of circulating nucleophosmin mutations DNA in the plasma of patients with acute myeloid leukemia. International journal of medical sciences 2015 12 (1): 17-22. Quan Jing, Gao Yu-jie, Yang Zai-lin, Chen Hui, Xian Jing-rong, Zhang Shuai-shuai, Zou Qin, Zhang Li |
| Prognostic implication of gene mutations on overall survival in the adult acute myeloid leukemia patients receiving or not receiving allogeneic hematopoietic stem cell transplantations. Leukemia research 2014 Nov 38 (11): 1278-84. Chou Sheng-Chieh, Tang Jih-Luh, Hou Hsin-An, Chou Wen-Chien, Hu Fu-Chang, Chen Chien-Yuan, Yao Ming, Ko Bor-Sheng, Huang Shang-Yi, Tsay Woei, Chen Yao-Chang, Tien Hwei-Fa |
| High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome. Leukemia 2014 Jul 28 (7): 1449-58. Krauth M-T, Eder C, Alpermann T, Bacher U, Nadarajah N, Kern W, Haferlach C, Haferlach T, Schnittger |
| BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS. American journal of hematology 2014 May 89 (5): 499-504. Zhang Liping, Singh Rajesh R, Patel Keyur P, Stingo Francesco, Routbort Mark, You M James, Miranda Roberto N, Garcia-Manero Guillermo, Kantarjian Hagop M, Medeiros L Jeffrey, Luthra Rajyalakshmi, Khoury Joseph |
| Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial. Blood 2014 May 123 (21): 3247-54. Stilgenbauer Stephan, Schnaiter Andrea, Paschka Peter, Zenz Thorsten, Rossi Marianna, Döhner Konstanze, Bühler Andreas, Böttcher Sebastian, Ritgen Matthias, Kneba Michael, Winkler Dirk, Tausch Eugen, Hoth Patrick, Edelmann Jennifer, Mertens Daniel, Bullinger Lars, Bergmann Manuela, Kless Sabrina, Mack Silja, Jäger Ulrich, Patten Nancy, Wu Lin, Wenger Michael K, Fingerle-Rowson Günter, Lichter Peter, Cazzola Mario, Wendtner Clemens M, Fink Anna M, Fischer Kirsten, Busch Raymonde, Hallek Michael, Döhner Hartm |
| Effect of NPM1 and FLT3 mutations on the outcomes of elderly patients with acute myeloid leukemia receiving standard chemotherapy. Clinical lymphoma, myeloma & leukemia 2013 Aug 13 (4): 435-40. Daver Naval, Liu Dumlao Theresa, Ravandi Farhad, Pierce Sherry, Borthakur Gautam, Pemmaraju Naveen, Nazha Aziz, Faderl Stefan, Jabbour Elias, Garcia-Manero Guillermo, Cortes Jorges, Kantarjian Hagop, Quintás-Cardama Alfon |
| Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG). Blood 2013 Jun 121 (23): 4769-77. Gaidzik Verena I, Schlenk Richard F, Paschka Peter, Stölzle Anja, Späth Daniela, Kuendgen Andrea, von Lilienfeld-Toal Marie, Brugger Wolfram, Derigs Hans Günter, Kremers Stephan, Greil Richard, Raghavachar Aruna, Ringhoffer Mark, Salih Helmut R, Wattad Mohammed, Kirchen Heinz G, Runde Volker, Heil Gerhard, Petzer Andreas L, Girschikofsky Michael, Heuser Michael, Kayser Sabine, Goehring Gudrun, Teleanu Maria-Veronica, Schlegelberger Brigitte, Ganser Arnold, Krauter Jürgen, Bullinger Lars, Döhner Hartmut, Döhner Konstan |
| Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse. Haematologica 2013 Apr 98 (4): 518-25. Pfeiffer Tim, Schleuning Michael, Mayer Jiri, Haude Karl-Heinz, Tischer Johanna, Buchholz Stefanie, Bunjes Donald, Bug Gesine, Holler Ernst, Meyer Ralf G, Greinix Hildegard, Scheid Christof, Christopeit Maximilian, Schnittger Susanne, Braess Jan, Schlimok Günter, Spiekermann Karsten, Ganser Arnold, Kolb Hans-Jochem, Schmid Christo |
| Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial. Leukemia 2013 Jan 27 (1): 41-7. Jenkinson S, Koo K, Mansour M R, Goulden N, Vora A, Mitchell C, Wade R, Richards S, Hancock J, Moorman A V, Linch D C, Gale R |
| Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases. Haematologica 2012 Dec 97 (12): 1890-4. Schnittger Susanne, Bacher Ulrike, Alpermann Tamara, Reiter Andreas, Ulke Madlen, Dicker Frank, Eder Christiane, Kohlmann Alexander, Grossmann Vera, Kowarsch Andreas, Kern Wolfgang, Haferlach Claudia, Haferlach Torst |
| Type and location of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid leukemia. Leukemia & lymphoma 2012 Oct . Koszarska M, Bors A, Feczko A, Meggyesi N, Batai A, Csomor J, Adam E, Kozma A, Orban TI, Lovas N, Sipos A, Karaszi E, Dolgos J, Fekete S, Reichardt J, Lehoczky E, Masszi T, Tordai A, Andrikovics H |
| CEBPA gene mutations in Egyptian acute myeloid leukemia patients: impact on prognosis. Hematology (Amsterdam, Netherlands) 2012 Sep . Awad MM, Aladle DA, Abousamra NK, Elghannam DM, Fawzy IM |
- Page last reviewed:Feb 1, 2023
- Page last updated:Mar 31, 2023
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