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Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans. Hepatology communications 2022 Jul . Ericson Elke, Bergenholm Linnéa, Andréasson Anne-Christine, Dix Carly I, Knöchel Jane, Hansson Sara F, Lee Richard, Schumi Jennifer, Antonsson Madeleine, Fjellström Ola, Nasr Patrik, Liljeblad Mathias, Carlsson Björn, Kechagias Stergios, Lindén Daniel, Ekstedt Matti |
Clinical and genetic determinants of the fatty liver-coagulation balance interplay in individuals with metabolic dysfunction. JHEP reports : innovation in hepatology 2022 10 4 (12): 100598. Valenti Luca, Tripodi Armando, La Mura Vincenzo, Pelusi Serena, Bianco Cristiana, Scalambrino Erica, Margarita Sara, Malvestiti Francesco, Ronzoni Luisa, Clerici Marigrazia, D'Ambrosio Roberta, Fraquelli Mirella, Carpani Rossana, Prati Daniele, Peyvandi Flo |
Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. Hepatology (Baltimore, Md.) 2022 5 77 (1): 197-212. Goyal Nidhi P, Rosenthal Sara B, Nasamran Chanod, Behling Cynthia A, Angeles Jorge E, Fishbein Mark H, Harlow Kathryn E, Jain Ajay K, Molleston Jean P, Newton Kimberly P, Ugalde-Nicalo Patricia, Xanthankos Stavra A, Yates Katherine, Schork Nicholas J, Fisch Kathleen M, Schwimmer Jeffrey B, |
The impact of single-nucleotide polymorphisms on liver stiffness and controlled attenuation parameter in patients treated with direct-acting antiviral drugs for hepatitis C infection. Biomedical reports 2022 1 16 (2): 9. Matsumoto Kosuke, Miyaaki Hisamitsu, Fukushima Masanori, Sasaki Ryu, Haraguchi Masafumi, Miuma Satoshi, Nakao Kazuhi |
Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17-beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms. Hepatology communications 2022 4 6 (8): 1934-1948. Hudert Christian A, Adams Leon A, Alisi Anna, Anstee Quentin M, Crudele Annalisa, Draijer Laura G, Furse Samuel, Hengstler Jan G, Jenkins Benjamin, Karnebeek Kylie, Kelly Deirdre A, Koot Bart G, Koulman Albert, Meierhofer David, Melton Phillip E, Mori Trevor A, Snowden Stuart G, van Mourik Indra, Vreugdenhil Anita, Wiegand Susanna, Mann Jake P, |
Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease. Liver international : official journal of the International Association for the Study of the Liver 2021 4 41 (7): 1576-1591. Lang Sonja, Martin Anna, Zhang Xinlian, Farowski Fedja, Wisplinghoff Hilmar, J G T Vehreschild Maria, Krawczyk Marcin, Nowag Angela, Kretzschmar Anne, Scholz Claus, Kasper Philipp, Roderburg Christoph, Mohr Raphael, Lammert Frank, Tacke Frank, Schnabl Bernd, Goeser Tobias, Steffen Hans-Michael, Demir Münevv |
Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020 Dec . Israelsen Mads, Juel Helene Bæk, Detlefsen Sönke, Madsen Bjørn Stæhr, Rasmussen Ditlev Nytoft, Larsen Trine R, Kjærgaard Maria, Fernandes Jensen Mary Jo, Stender Stefan, Hansen Torben, Krag Aleksander, Thiele Maja, |
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis.
![]() Journal of hepatology 2020 Aug 73 (2): 241-251. Parisinos Constantinos A, Wilman Henry R, Thomas E Louise, Kelly Matt, Nicholls Rowan C, McGonigle John, Neubauer Stefan, Hingorani Aroon D, Patel Riyaz S, Hemingway Harry, Bell Jimmy D, Banerjee Rajarshi, Yaghootkar Hani |
PNPLA3 rs738409 associates with alcoholic liver cirrhosis but not with serum levels of IL6, IL10, IL8 or CCL2 in the Russian population. Annals of hepatology 2020 Aug . Peregud Danil I, Baronets Valeria Yu, Lobacheva Anna S, Ivanov Alexandr S, Arisheva Olga S, Garmash Irina V, Kobalava Zhanna D, Pirozhkov Sergey V, Terebilina Natalia |
Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease. Liver international : official journal of the International Association for the Study of the Liver 2020 Apr . Seko Yuya, Yamaguchi Kanji, Tochiki Nozomi, Yano Kota, Takahashi Aya, Okishio Shinya, Kataoka Seita, Okuda Keiichiroh, Umemura Atsushi, Moriguchi Michihisa, Tanaka Saiyu, Mori Kojiroh, Okanoue Takeshi, Itoh Yoshi |
PNPLA3 I148M is involved in the variability in anti-NAFLD response to exenatide. Endocrine 2020 8 70 (3): 517-525. Chen Yunzhi, Yan Xuemei, Xu Xiao, Yuan Shuhua, Xu Fen, Liang H |
PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020 9 19 (9): 1979-1981. Pennisi Grazia, Pipitone Rosaria Maria, Cammà Calogero, Di Marco Vito, Di Martino Vincenzo, Spatola Federica, Zito Rossella, Craxì Antonio, Grimaudo Stefania, Petta Salvato |
PNPLA3-A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease. Frontiers in medicine 2020 1 6 304. Dong Xiaocheng Charl |
Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis. Hepatology communications 2020 7 4 (7): 953-972. Young Steven, Tariq Raseen, Provenza John, Satapathy Sanjaya K, Faisal Kamal, Choudhry Abhijit, Friedman Scott L, Singal Ashwani |
The ATG16L1 gene variant rs2241880 (p.T300A) is associated with susceptibility to HCC in patients with cirrhosis. Liver international : official journal of the International Association for the Study of the Liver 2019 Sep . Reuken Philipp A, Lutz Philipp, Casper Markus, Al-Herwi Eihab, Stengel Sven, Spengler Ulrich, Stallmach Andreas, Lammert Frank, Nischalke Hans Dieter, Bruns To |
Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
![]() Alcoholism, clinical and experimental research 2019 Mar 43 (3): 473-482. Whitfield John B, Zhu Gu, Madden Pamela A F, Montgomery Grant W, Heath Andrew C, Martin Nicholas |
Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease. Liver international : official journal of the International Association for the Study of the Liver 2019 Mar 39 (3): 540-556. Hudert Christian A, Selinski Silvia, Rudolph Birgit, Bläker Hendrik, Loddenkemper Christoph, Thielhorn Ria, Berndt Nikolaus, Golka Klaus, Cadenas Cristina, Reinders Jörg, Henning Stephan, Bufler Philip, Jansen Peter L M, Holzhütter Hermann-Georg, Meierhofer David, Hengstler Jan G, Wiegand Susan |
Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. Diabetologia 2019 11 63 (2): 253-260. Brouwers Martijn C G J, Simons Nynke, Stehouwer Coen D A, Isaacs Aar |
PNPLA3 rs139051 is associated with phospholipid metabolite profile and hepatic inflammation in nonalcoholic fatty liver disease. World journal of clinical cases 2018 Sep 6 (10): 355-364. Luo Ji-Jun, Cao Hai-Xia, Yang Rui-Xu, Zhang Rui-Nan, Pan Q |
Role of the PNPLA3 polymorphism rs738409 on silymarin + vitamin E response in subjects with non-alcoholic fatty liver disease. Revista espanola de enfermedades digestivas 2018 7 110 (10): 634-640. Aller Rocío, Laserna Cristina, Rojo Miguel Ángel, Mora Natalia, García Sánchez Concepción, Pina María, Sigüenza Rebeca, Durà Miguel, Primo David, Izaola Olatz, de Luis Dani |
Suppressed Fat Mobilization Due to PNPLA3 rs738409 -Associated Liver Damage in Heavy Drinkers: The Liver Damage Feedback Hypothesis. Advances in experimental medicine and biology 2018 10 1032 153-172. Rausch Vanessa, Mueller Sebasti |
Identification of pleiotropic genetic variants affecting osteoporosis risk in a Korean elderly cohort. Journal of bone and mineral metabolism 2017 Dec . Hong Eun Pyo, Rhee Ka Hyun, Kim Dong Hyun, Park Ji W |
Association of single nucleotide polymorphism at PNPLA3 with fatty liver, steatohepatitis, and cirrhosis of liver. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2017 Sep 36 (5): 366-372. Alam Shahinul, Islam Mohammad Shaiful, Islam Saiful, Mustafa Golam, Saleh Ahmed Abu, Ahmad Noorudd |
Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2017 May . Fracanzani Anna Ludovica, Petta Salvatore, Lombardi Rosa, Pisano Giuseppina, Russello Maurizio, Consonni Dario, Di Marco Vito, Cammà Calogero, Mensi Laura, Dongiovanni Paola, Valenti Luca, Craxì Antonio, Fargion Silv |
Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease. The American journal of gastroenterology 2017 May . Bugianesi Elisabetta, Bizzarri Carla, Rosso Chiara, Mosca Antonella, Panera Nadia, Veraldi Silvio, Dotta Andrea, Giannone Germana, Raponi Massimiliano, Cappa Marco, Alisi Anna, Nobili Valer |
Hepatic nucleotide binding oligomerization domain-like receptors pyrin domain-containing 3 inflammasomes are associated with the histologic severity of non-alcoholic fatty liver disease. Hepatology research : the official journal of the Japan Society of Hepatology 2017 Feb . Mitsuyoshi Hironori, Yasui Kohichiroh, Hara Tasuku, Taketani Hiroyoshi, Ishiba Hiroshi, Okajima Akira, Seko Yuya, Umemura Atsushi, Nishikawa Taichiro, Yamaguchi Kanji, Moriguchi Michihisa, Minami Masahito, Itoh Yoshi |
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver. Journal of internal medicine 2017 12 283 (4): 356-370. Dongiovanni P, Stender S, Pietrelli A, Mancina R M, Cespiati A, Petta S, Pelusi S, Pingitore P, Badiali S, Maggioni M, Mannisto V, Grimaudo S, Pipitone R M, Pihlajamaki J, Craxi A, Taube M, Carlsson L M S, Fargion S, Romeo S, Kozlitina J, Valenti |
Primary liver injury and delayed resolution of liver stiffness after alcohol detoxification in heavy drinkers with the PNPLA3 variant I148M. World journal of hepatology 2017 1 8 (35): 1547-1556. Rausch Vanessa, Peccerella Teresa, Lackner Carolin, Yagmur Eray, Seitz Helmut-Karl, Longerich Thomas, Mueller Sebasti |
Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors. Hepatology research : the official journal of the Japan Society of Hepatology 2016 Jan . Honda Yasushi, Yoneda Masato, Kessoku Takaomi, Ogawa Yuji, Tomeno Wataru, Imajo Kento, Mawatari Hironori, Fujita Koji, Hyogo Hideyuki, Ueno Takato, Chayama Kazuaki, Saito Satoru, Nakajima Atsushi, Hotta Kiku |
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes. Inflammatory bowel diseases 2015 Sep . Mancina Rosellina Margherita, Spagnuolo Rocco, Milano Marta, Brogneri Simona, Morrone Attilio, Cosco Cristina, Lazzaro Veronica, Russo Cristina, Ferro Yvelise, Pingitore Piero, Pujia Arturo, Montalcini Tiziana, Doldo Patrizia, Garieri Pietro, Piodi Luca, Caprioli Flavio, Valenti Luca, Romeo Stefa |
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- Page last updated:Mar 31, 2023
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