HuGE Literature Finder
Records 1-30
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The Temporal Sequence and the Differences in Somatic Mutation Acquisition Determines Clinical Behaviors of JAK2-Positive Myeloproliferative Neoplasms.
Anticancer research 2019 Nov 39 (11): 6273-6282. Byun Ja Min, Song Seulki, Koh Youngil, Yoon Sung-Soo, Kim Daeyo |
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Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation.
Annals of hematology 2019 Jul . Caballero Juan Carlos, Sánchez Barba Mercedes, Hernández Sánchez Jesús María, Such Esperanza, Janusz Kamila, Sanz Guillermo, Cabrero Mónica, Chillón Carmen, Cervera José, Hurtado Ana María, Jerez Andrés, Calderón Cabrera Cristina, Valcárcel David, Lumbreras Eva, Abáigar María, López Cadenas Félix, Hernández Rivas Jesús María, Del Cañizo María Consuelo, Díez Campelo Mar |
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[Clinical Characteristics and Karyotype Analysis of Myelodysplastic Syndrome Patients with TP53 mutation].
Zhongguo shi yan xue ye xue za zhi 2019 Jun 27 (3): 872-876. Zhou Xu-Yan, Ouyang Gui-Fang, Mu Qi-Tian, Sheng Li-X |
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Genomic subtyping and therapeutic targeting of acute erythroleukemia.
Nature genetics 2019 Apr 51 (4): 694-704. Iacobucci Ilaria, Wen Ji, Meggendorfer Manja, Choi John K, Shi Lei, Pounds Stanley B, Carmichael Catherine L, Masih Katherine E, Morris Sarah M, Lindsley R Coleman, Janke Laura J, Alexander Thomas B, Song Guangchun, Qu Chunxu, Li Yongjin, Payne-Turner Debbie, Tomizawa Daisuke, Kiyokawa Nobutaka, Valentine Marcus, Valentine Virginia, Basso Giuseppe, Locatelli Franco, Enemark Eric J, Kham Shirley K Y, Yeoh Allen E J, Ma Xiaotu, Zhou Xin, Sioson Edgar, Rusch Michael, Ries Rhonda E, Stieglitz Elliot, Hunger Stephen P, Wei Andrew H, To L Bik, Lewis Ian D, D'Andrea Richard J, Kile Benjamin T, Brown Anna L, Scott Hamish S, Hahn Christopher N, Marlton Paula, Pei Deqing, Cheng Cheng, Loh Mignon L, Ebert Benjamin L, Meshinchi Soheil, Haferlach Torsten, Mullighan Charles |
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Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients.
Leukemia 2019 Apr . Mithraprabhu Sridurga, Morley Rachel, Khong Tiffany, Kalff Anna, Bergin Krystal, Hocking Jay, Savvidou Ioanna, Bowen Kathryn M, Ramachandran Malarmathy, Choi Kawa, Wong Boris Ka Leong, Reynolds John, Spencer Andr |
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Myeloid malignancies with isolated 7q deletion can be further characterized by their accompanying molecular mutations.
Genes, chromosomes & cancer 2019 Apr . Hartmann Luise, Haferlach Claudia, Meggendorfer Manja, Kern Wolfgang, Haferlach Torsten, Stengel An |
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Copy number alterations and copy-neutral loss of heterozygosity in Ukrainian patients with primary myelofibrosis.
Experimental oncology 2019 Mar 41 (1): 53-56. Poluben L, Bryke Ch R, Hsu Y, Shumeiko O, Neumerzhitska L, Klimuk B, Rybchenko L, Klymenko S, Balk S P, Fraenkel P |
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Genetic and transcriptional landscape of plasma cells in POEMS syndrome.
Leukemia 2019 Jan . Nagao Yuhei, Mimura Naoya, Takeda June, Yoshida Kenichi, Shiozawa Yusuke, Oshima Motohiko, Aoyama Kazumasa, Saraya Atsunori, Koide Shuhei, Rizq Ola, Hasegawa Yoshinori, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Nishijima Dai, Isshiki Yusuke, Kayamori Kensuke, Kawajiri-Manako Chika, Oshima-Hasegawa Nagisa, Tsukamoto Shokichi, Mitsukawa Shio, Takeda Yusuke, Ohwada Chikako, Takeuchi Masahiro, Iseki Tohru, Misawa Sonoko, Miyano Satoru, Ohara Osamu, Yokote Koutaro, Sakaida Emiko, Kuwabara Satoshi, Sanada Masashi, Iwama Atsushi, Ogawa Seishi, Nakaseko Chia |
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High sub-clonal fraction of 17p deletion is associated with poor prognosis in Multiple Myeloma.
Blood 2019 Jan . Thakurta Anjan, Ortiz Maria, Blecua Pedro, Towfic Fadi, Corre Jill, Serbina Natalya V, Flynt Erin, Yu Zhinuan, Yang Zhihong, Palumbo Antonio, Dimopoulos Meletios A, Guttierez Norma, Goldschmidt Hartmut, Sonneveld Pieter, Avet-Loiseau Her |
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TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.
Leukemia 2019 Jan . Haase Detlef, Stevenson Kristen E, Neuberg Donna, Maciejewski Jaroslaw P, Nazha Aziz, Sekeres Mikkael A, Ebert Benjamin L, Garcia-Manero Guillermo, Haferlach Claudia, Haferlach Torsten, Kern Wolfgang, Ogawa Seishi, Nagata Yasunobu, Yoshida Kenichi, Graubert Timothy A, Walter Matthew J, List Alan F, Komrokji Rami S, Padron Eric, Sallman David, Papaemmanuil Elli, Campbell Peter J, Savona Michael R, Seegmiller Adam, Adès Lionel, Fenaux Pierre, Shih Lee-Yung, Bowen David, Groves Michael J, Tauro Sudhir, Fontenay Michaela, Kosmider Olivier, Bar-Natan Michal, Steensma David, Stone Richard, Heuser Michael, Thol Felicitas, Cazzola Mario, Malcovati Luca, Karsan Aly, Ganster Christina, Hellström-Lindberg Eva, Boultwood Jacqueline, Pellagatti Andrea, Santini Valeria, Quek Lynn, Vyas Paresh, Tüchler Heinz, Greenberg Peter L, Bejar Rafael, |
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Analysis of clinical and molecular features of MDS patients with complex karyotype in China.
Blood cells, molecules & diseases 2018 Nov 75 13-19. Ren Yanling, Mei Chen, Ye Li, Luo Yingwan, Zhou Xinping, Yang Haiyang, Lin Peipei, Xu Weilai, Ma Liya, Jin Jie, Tong Hongy |
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[Clinical Characteristic of "triple-negative" Essential Thrombocythaemia Patients and Mutation Analysis by Targeted Sequencing].
Zhongguo shi yan xue ye xue za zhi 2018 Aug 26 (4): 1137-1145. Ju Man-Kai, Fu Rong-Feng, Li Hui-Yuan, Liu Xiao-Fan, Xue Feng, Chen Yun-Fei, Huang Yue-Ting, Zhang Li-Yan, Yang Ren-Chi, Zhang L |
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Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome.
Blood cancer journal 2018 Apr 8 (4): 39. Hou Hsin-An, Tsai Cheng-Hong, Lin Chien-Chin, Chou Wen-Chien, Kuo Yuan-Yeh, Liu Chieh-Yu, Tseng Mei-Hsuan, Peng Yen-Ling, Liu Ming-Chih, Liu Chia-Wen, Liao Xiu-Wen, Lin Liang-In, Yao Ming, Tang Jih-Luh, Tien Hwei-Fa |
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Single-agent panobinostat for relapsed/refractory diffuse large B-cell lymphoma: clinical outcome and correlation with genomic data. A phase 2 study of the Fondazione Italiana Linfomi.
Leukemia & lymphoma 2018 Apr 1-7. Zaja Francesco, Salvi Flavia, Rossi Maura, Sabattini Elena, Evangelista Andrea, Ciccone Giovannino, Angelucci Emanuele, Gaidano Gianluca, Zanni Manuela, Ladetto Marco, Chiappella Annalisa, Vitolo Umberto, Zinzani Pier Luigi, Califano Catello, Tucci Alessandra, Patti Caterina, Pileri Stefano A, Lenti Valentina, Piccaluga Pier Paolo, Cavallo Federica, Volpetti Stefano, Perali Giulia, Assouline Sarit, Mann Koren Kathleen, Morin Ryan, Alcaide Miguel, Bushell Kevin, Fanin Renato, Levis Alessand |
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Chronic Myelomonocytic Leukemia With Fibrosis is a Distinct Disease Subset With Myeloproliferative Features and Frequent JAK2 p.V617F Mutations.
The American journal of surgical pathology 2018 Mar . Deniz Gur, Loghavi Sanam, Garcia-Manero Guillermo, Routbort Mark, Kanagal-Shamanna Rashmi, Quesada Andres, Khogeer Haitham, Pierce Sherry, Medeiros L Jeffrey, Kantarjian Hagop, Khoury Joseph |
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Mutations and prognosis in myelodysplastic syndromes: Karyotype-adjusted analysis of targeted sequencing in 300 consecutive cases and development of a genetic risk model.
American journal of hematology 2018 Feb . Gangat Naseema, Mudireddy Mythri, Lasho Terra L, Finke Christy M, Nicolosi Maura, Szuber Natasha, Patnaik Mrinal M, Pardanani Animesh, Hanson Curtis A, Ketterling Rhett P, Tefferi Ayal |
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TP53 polymorphism in plasma cell myeloma.
Folia histochemica et cytobiologica 2018 Jan . Zmorzynski Szymon Andrzej, Korszen-Pilecka Iwona, Wojcierowska-Litwin Magdalena, Kwiatkowska-Drabik Barbara, Luterek Malgorzata, Chocholska Sylwia, Koczkodaj Dorota, Popek Sylwia, Michalak-Wojnowska Malgorzata, Swiderska-Kolacz Grazyna, Januszewska Joanna, Surowiec Iwona, Tomczak Waldemar, Hus Marek, Dmoszynska Anna, Pasiarski Marcin, Poniewierska-Jasak Katarzyna, Cieplinska Katarzyna, Jankowska-Lecka Olga, Filip Agata An |
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Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.
Blood advances 2018 01 2 (2): 146-150. Drazer Michael W, Kadri Sabah, Sukhanova Madina, Patil Sushant A, West Allison H, Feurstein Simone, Calderon Dalein A, Jones Matthew F, Weipert Caroline M, Daugherty Christopher K, Ceballos-López Adrián A, Raca Gordana, Lingen Mark W, Li Zejuan, Segal Jeremy P, Churpek Jane E, Godley Lucy |
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TP53 mutation in allogeneic hematopoietic cell transplantation for de novo myelodysplastic syndrome.
Leukemia research 2018 11 74 97-104. Kim Yoo-Jin, Jung Seung-Hyun, Hur Eun-Hye, Choi Eun-Ji, Lee Kyoo-Hyung, Yim Seon-Hee, Kim Hye-Jung, Kwon Yong-Rim, Jeon Young-Woo, Lee Sug Hyung, Chung Yeun-Jun, Lee Je-Hw |
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Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases.
PLoS genetics 2017 Nov 13 (11): e1007087. Manojlovic Zarko, Christofferson Austin, Liang Winnie S, Aldrich Jessica, Washington Megan, Wong Shukmei, Rohrer Daniel, Jewell Scott, Kittles Rick A, Derome Mary, Auclair Daniel, Craig David Wesley, Keats Jonathan, Carpten John |
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Impact of gene mutations on treatment response and prognosis of acute myeloid leukemia secondary to myeloproliferative neoplasms.
American journal of hematology 2017 Nov . Venton G, Courtier F, Charbonnier A, D'Incan E, Saillard C, Mohty B, Mozziconacci M J, Birnbaum D, Murati A, Vey N, Rey |
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TP53 mutation does not confer a poor outcome in adult patients with acute lymphoblastic leukemia who are treated with frontline hyper-CVAD-based regimens.
Cancer 2017 Oct 123 (19): 3717-3724. Kanagal-Shamanna Rashmi, Jain Preetesh, Takahashi Koichi, Short Nicholas J, Tang Guilin, Issa Ghayas C, Ravandi Farhad, Garcia-Manero Guillermo, Yin Cameron C, Luthra Rajyalakshmi, Patel Keyur P, Khoury Joseph D, Montalban-Bravo Guillermo, Sasaki Koji, Kadia Tapan M, Borthakur Gautam, Konopleva Marina, Jain Nitin, Garris Rebecca, Pierce Sherry, Wierda William, Estrov Zeev, Cortes Jorge, O'Brien Susan, Kantarjian Hagop M, Jabbour Eli |
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Targeted next-generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS-R.
American journal of hematology 2017 Sep . Tefferi Ayalew, Lasho Terra L, Patnaik Mrinal M, Saeed Lyla, Mudireddy Mythri, Idossa Dame, Finke Christy, Ketterling Rhett P, Pardanani Animesh, Gangat Nasee |
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Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes.
Cell stem cell 2017 Aug . Coombs Catherine C, Zehir Ahmet, Devlin Sean M, Kishtagari Ashwin, Syed Aijazuddin, Jonsson Philip, Hyman David M, Solit David B, Robson Mark E, Baselga José, Arcila Maria E, Ladanyi Marc, Tallman Martin S, Levine Ross L, Berger Michael |
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Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: Association with age, hydroxyurea administration, disease type and JAK2 mutational status.
Leukemia 2017 Jul . Kubesova B, Pavlova S, Malcikova J, Kabathova J, Radova L, Tom N, Tichy B, Plevova K, Kantorova B, Fiedorova K, Slavikova M, Bystry V, Kissova J, Gisslinger B, Gisslinger H, Penka M, Mayer J, Kralovics R, Pospisilova S, Doubek |
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TP53 mutation and its prognostic significance in Waldenstrom's Macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Jul . Poulain Stéphanie, Roumier Christophe, Bertrand Elisabeth, Renneville Aline, Venet-Caillault Aurelie, Doye Emmanuelle, Geffroy Sandrine, Sebda Scheherazade, Nibourel Olivier, Nudel Morgane, Herbaux Charles, Renaud Loic, Tomowiak Cecile, Guidez Stéphanie, Tricot Sabine, Roche-Lestienne Catherine, Quesnel Bruno, Preudhomme Claude, Leleu Xavi |
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Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation.
Annals of hematology 2017 Jun . Heuser Michael, Gabdoulline Razif, Löffeld Patrick, Dobbernack Vera, Kreimeyer Henriette, Pankratz Mira, Flintrop Madita, Liebich Alessandro, Klesse Sabrina, Panagiota Victoria, Stadler Michael, Wichmann Martin, Shahswar Rabia, Platzbecker Uwe, Thiede Christian, Schroeder Thomas, Kobbe Guido, Geffers Robert, Schlegelberger Brigitte, Göhring Gudrun, Kreipe Hans-Heinrich, Germing Ulrich, Ganser Arnold, Kröger Nicolaus, Koenecke Christian, Thol Felicit |
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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.
European journal of cancer (Oxford, England : 1990) 2017 Mar 76 144-151. de Jonge Maja, de Weger Vincent A, Dickson Mark A, Langenberg Marlies, Le Cesne Axel, Wagner Andrew J, Hsu Karl, Zheng Wei, Macé Sandrine, Tuffal Gilles, Thomas Koruth, Schellens Jan H |
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Impact of genetic alterations in stem-cell transplantation for myelodysplasia and secondary acute myeloid leukemia.
Blood 2017 Feb . Yoshizato Tetsuichi, Nannya Yasuhito, Atsuta Yoshiko, Shiozawa Yusuke, Iijima-Yamashita Yuka, Yoshida Kenichi, Shiraishi Yuichi, Suzuki Hiromichi, Nagata Yasunobu, Sato Yusuke, Kakiuchi Nobuyuki, Matsuo Keitaro, Onizuka Makoto, Kataoka Keisuke, Chiba Kenichi, Tanaka Hiroko, Ueno Hiroo, Nakagawa Masahiro M, Przychodzen Bartlomiej, Haferlach Claudia, Kern Wolfgang, Aoki Kosuke, Itonaga Hidehiro, Kanda Yoshinobu, Sekeres Mikkael A, Maciejewski Jaroslaw P, Haferlach Torsten, Miyazaki Yasushi, Horibe Keizo, Sanada Masashi, Miyano Satoru, Makishima Hideki, Ogawa Seis |
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Mutational landscape reflects the biological continuum of plasma cell dyscrasias.
Blood cancer journal 2017 Feb 7 (2): e537. Rossi A, Voigtlaender M, Janjetovic S, Thiele B, Alawi M, März M, Brandt A, Hansen T, Radloff J, Schön G, Hegenbart U, Schönland S, Langer C, Bokemeyer C, Binder |
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Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant.
Molecular carcinogenesis 2017 Feb . Poi Ming J, Li Junan, Sborov Douglas W, VanGundy Zachary, Cho Yu Kyoung, Lamprecht Misty, Pichiorri Flavia, Phelps Mitch A, Hofmeister Craig |
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The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma.
Oncotarget 2017 Feb . Stein Caleb K, Pawlyn Charlotte, Chavan Shweta, Rasche Leo, Weinhold Niels, Corken Adam, Buros Amy, Sonneveld Pieter, Jackson Graham H, Landgren Ola, Mughal Tariq, He Jie, Barlogie Bart, Leif Bergsagel P, Davies Faith E, Walker Brian A, Morgan Gareth |
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Idiopathic hypereosinophilia is clonal disorder? Clonality identified by targeted sequencing.
PloS one 2017 12 (10): e0185602. Lee Jee-Soo, Seo Heewon, Im Kyongok, Park Si Nae, Kim Sung-Min, Lee Eun Kyoung, Kim Jung-Ah, Lee Joon-Hee, Kwon Sunghoon, Kim Miyoung, Koh Insong, Hwang Seungwoo, Park Heung-Woo, Kang Hye-Ryun, Park Kyoung Soo, Kim Ju Han, Lee Dong So |
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Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia.
British journal of haematology 2017 09 178 (5): 764-771. Alvarez-Larrán Alberto, Senín Alicia, Fernández-Rodríguez Concepción, Pereira Arturo, Arellano-Rodrigo Eduardo, Gómez Montse, Ferrer-Marin Francisca, Martínez-López Joaquín, Camacho Laura, Colomer Dolors, Angona Anna, Navarro Blanca, Cervantes Francisco, Besses Carlos, Bellosillo Beatriz, Hernández-Boluda Juan Carl |
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Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.
The New England journal of medicine 2017 02 376 (6): 536-547. Lindsley R Coleman, Saber Wael, Mar Brenton G, Redd Robert, Wang Tao, Haagenson Michael D, Grauman Peter V, Hu Zhen-Huan, Spellman Stephen R, Lee Stephanie J, Verneris Michael R, Hsu Katharine, Fleischhauer Katharina, Cutler Corey, Antin Joseph H, Neuberg Donna, Ebert Benjamin |
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The impact of TP53 mutations and TP53 deletions on survival varies between AML, ALL, MDS and CLL-an analysis of 3307 cases.
Leukemia 2016 Sep . Stengel A, Kern W, Haferlach T, Meggendorfer M, Fasan A, Haferlach |
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Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome.
Oncotarget 2016 Jul . Jung Seung-Hyun, Kim Yoo-Jin, Yim Seon-Hee, Kim Hye-Jung, Kwon Yong-Rim, Hur Eun-Hye, Goo Bon-Kwan, Choi Yun-Suk, Lee Sug Hyung, Chung Yeun-Jun, Lee Je-Hw |
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TP53 codon 72 polymorphism predicts chronic myeloid leukemia susceptibility and treatment outcome.
Blood cells, molecules & diseases 2016 Jul 59 129-33. Weich Natalia, Ferri Cristian, Moiraghi Beatriz, Bengió Raquel, Giere Isabel, Pavlovsky Carolina, Larripa Irene, Fundia Arie |
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Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations.
Oncotarget 2016 Jun . Shin Sang-Yong, Lee Seung-Tae, Kim Hee-Jin, Cho Eun Hae, Kim Jong-Won, Park Silvia, Jung Chul Won, Kim Sun-H |
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The 5q deletion size in myeloid malignancies is correlated to additional chromosomal aberrations and to TP53 mutations.
Genes, chromosomes & cancer 2016 May . Stengel Anna, Kern Wolfgang, Haferlach Torsten, Meggendorfer Manja, Haferlach Claud |
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TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes.
Oncotarget 2016 May . Belickova Monika, Vesela Jitka, Jonasova Anna, Pejsova Barbora, Votavova Hana, Merkerova Michaela Dostalova, Zemanova Zuzana, Brezinova Jana, Mikulenkova Dana, Lauermannova Marie, Valka Jan, Michalova Kyra, Neuwirtova Radana, Cermak Jarosl |
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Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes.
Leukemia research 2016 Jan 42 7-12. Svobodova Karla, Zemanova Zuzana, Lhotska Halka, Novakova Milena, Podskalska Lucie, Belickova Monika, Brezinova Jana, Sarova Iveta, Izakova Silvia, Lizcova Libuse, Berkova Adela, Siskova Magda, Jonasova Anna, Cermak Jaroslav, Michalova Ky |
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Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes.
PloS one 2016 11 (10): e0164370. Abáigar María, Robledo Cristina, Benito Rocío, Ramos Fernando, Díez-Campelo María, Hermosín Lourdes, Sánchez-Del-Real Javier, Alonso Jose M, Cuello Rebeca, Megido Marta, Rodríguez Juan N, Martín-Núñez Guillermo, Aguilar Carlos, Vargas Manuel, Martín Ana A, García Juan L, Kohlmann Alexander, Del Cañizo M Consuelo, Hernández-Rivas Jesús |
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Short telomere length and its correlation with gene mutations in myelodysplastic syndrome.
Journal of hematology & oncology 2016 9 (1): 62. Hwang Sang Mee, Kim Seon Young, Kim Jung Ah, Park Hee-Sue, Park Si Nae, Im Kyongok, Kim Kwantae, Kim Sung-Min, Lee Dong So |
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Clinical and molecular response to interferon alpha therapy in essential thrombocythemia patients with CALR mutations.
Blood 2015 Oct . Verger Emmanuelle, Cassinat Bruno, Chauveau Aurélie, Dosquet Christine, Giraudier Stephane, Schlageter Marie-Hélène, Ianotto Jean-Christophe, Yassin Mohammed A, Al-Dewik Nader, Carillo Serge, Legouffe Eric, Ugo Valerie, Chomienne Christine, Kiladjian Jean-Jacqu |
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Influence of total genomic alteration and chromosomal fragmentation on response to a combination of azacitidine and lenalidomide in a cohort of patients with very high risk MDS.
Leukemia research 2015 Oct 39 (10): 1079-87. Ganster Christina, Shirneshan Katayoon, Salinas-Riester Gabriela, Braulke Friederike, Schanz Julie, Platzbecker Uwe, Haase Detl |
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Single Nucleotide Polymorphisms in TP53 but not KRAS or MDM2 are predictive of clinical outcome in multiple myeloma treated with High-Dose Melphalan and Autologous Stem Cell Support.
Leukemia & lymphoma 2015 Sep 1-11. Gebauer Niklas, Biersack Harald, Czerwinska Ann-Cathrin, Schemme Janina, Hardel Tim Tristan, Bernard Veronica, Rades Dirk, Lehnert Hendrik, Luley Kim Barbara, Thorns Christo |
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SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts.
Blood 2015 Jul 126 (2): 233-41. Malcovati Luca, Karimi Mohsen, Papaemmanuil Elli, Ambaglio Ilaria, Jädersten Martin, Jansson Monika, Elena Chiara, Gallì Anna, Walldin Gunilla, Della Porta Matteo G, Raaschou-Jensen Klas, Travaglino Erica, Kallenbach Klaus, Pietra Daniela, Ljungström Viktor, Conte Simona, Boveri Emanuela, Invernizzi Rosangela, Rosenquist Richard, Campbell Peter J, Cazzola Mario, Hellström Lindberg E |
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Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases.
Leukemia research 2015 Mar 39 (3): 348-54. Ok Chi Young, Patel Keyur P, Garcia-Manero Guillermo, Routbort Mark J, Fu Bin, Tang Guilin, Goswami Maitrayee, Singh Rajesh, Kanagal-Shamanna Rashmi, Pierce Sherry A, Young Ken H, Kantarjian Hagop M, Medeiros L Jeffrey, Luthra Rajyalakshmi, Wang Sa |
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MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation.
Human pathology 2015 Jan 46 (1): 65-73. Tang Guilin, DiNardo Courtney, Zhang Liping, Ravandi Farhad, Khoury Joseph D, Huh Yang O, Muzzafar Tariq, Medeiros L Jeffrey, Wang Sa A, Bueso-Ramos Carlos |
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Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.
PloS one 2015 10 (4): e0123476. Kirschner Martin M J, Schemionek Mirle, Schubert Claudia, Chatain Nicolas, Sontag Stephanie, Isfort Susanne, Ortiz-Brüchle Nadina, Schmitt Karla, Krüger Luisa, Zerres Klaus, Zenke Martin, Brümmendorf Tim H, Koschmieder Steff |
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The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes.
Blood cancer journal 2015 5 e291. McGraw K L, Zhang L M, Rollison D E, Basiorka A A, Fulp W, Rawal B, Jerez A, Billingsley D L, Lin H-Y, Kurtin S E, Yoder S, Zhang Y, Guinta K, Mallo M, Solé F, Calasanz M J, Cervera J, Such E, González T, Nevill T J, Haferlach T, Smith A E, Kulasekararaj A, Mufti G, Karsan A, Maciejewski J P, Sokol L, Epling-Burnette P K, Wei S, List A |
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TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
Blood 2014 Oct 124 (17): 2705-12. Bejar Rafael, Lord Allegra, Stevenson Kristen, Bar-Natan Michal, Pérez-Ladaga Albert, Zaneveld Jacques, Wang Hui, Caughey Bennett, Stojanov Petar, Getz Gad, Garcia-Manero Guillermo, Kantarjian Hagop, Chen Rui, Stone Richard M, Neuberg Donna, Steensma David P, Ebert Benjamin |
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Gene polymorphisms of p53-mediated apoptosis in chronic lymphocytic leukemia patients: features of distribution depending on radiation factor in anamnesis.
Problemy radiatsiinoi medytsyny ta radiobiolohii 2014 Sep 19 223-230. Bilous N I, Abramenko I V, Chumak A A, Dyagil I S, Martina Z |
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Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2014 Sep 32 (25): 2691-8. Bejar Rafael, Stevenson Kristen E, Caughey Bennett, Lindsley R Coleman, Mar Brenton G, Stojanov Petar, Getz Gad, Steensma David P, Ritz Jerome, Soiffer Robert, Antin Joseph H, Alyea Edwin, Armand Philippe, Ho Vincent, Koreth John, Neuberg Donna, Cutler Corey S, Ebert Benjamin |
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Detection p53 gene deletion in hematological malignancies using fluorescence in situ hybridization: a pilot study. .
Pakistan journal of biological sciences : PJBS 2014 Jul 17 (7): 891-7. Annooz Aaedah F, Melconian Alice K, Abdul-Majeed Ban A, Jawad Ali |
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Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine.
Leukemia research 2014 Jul 38 (7): 751-5. Bally Cecile, Adès Lionel, Renneville Aline, Sebert Marie, Eclache Virginie, Preudhomme Claude, Mozziconacci Marie-Joelle, de The Hugues, Lehmann-Che Jacqueline, Fenaux Pier |
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Autoimmune cytopenias in chronic lymphocytic leukemia at disease presentation in the modern treatment era: is stage C always stage C?
Leukemia & lymphoma 2014 Jun 55 (6): 1261-5. Visco Carlo, Cortelezzi Agostino, Moretta Francesca, Falisi Erika, Maura Francesco, Finotto Silvia, Barcellini Wilma, Ambrosetti Achille, Neri Antonino, Ruggeri Marco, Rodeghiero Frances |
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Association of the type of 5q loss with complex karyotype, clonal evolution, TP53 mutation status, and prognosis in acute myeloid leukemia and myelodysplastic syndrome.
Genes, chromosomes & cancer 2014 May 53 (5): 402-10. Volkert Sarah, Kohlmann Alexander, Schnittger Susanne, Kern Wolfgang, Haferlach Torsten, Haferlach Claud |
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Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms.
Blood 2014 Apr 123 (14): 2220-8. Lundberg Pontus, Karow Axel, Nienhold Ronny, Looser Renate, Hao-Shen Hui, Nissen Ina, Girsberger Sabine, Lehmann Thomas, Passweg Jakob, Stern Martin, Beisel Christian, Kralovics Robert, Skoda Radek |
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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.
Cancer cell 2014 Jan 25 (1): 91-101. Lohr Jens G, Stojanov Petar, Carter Scott L, Cruz-Gordillo Peter, Lawrence Michael S, Auclair Daniel, Sougnez Carrie, Knoechel Birgit, Gould Joshua, Saksena Gordon, Cibulskis Kristian, McKenna Aaron, Chapman Michael A, Straussman Ravid, Levy Joan, Perkins Louise M, Keats Jonathan J, Schumacher Steven E, Rosenberg Mara, , Getz Gad, Golub Todd |
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MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.
Oncology research and treatment 2014 37 (4): 176-80. Wang Xu, Wang Yi-Zhuo, Ma Ke-Wei, Chen Xiao, Li W |
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Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.
Haematologica 2013 Dec 98 (12): 1856-64. Fernandez-Mercado Marta, Burns Adam, Pellagatti Andrea, Giagounidis Aristoteles, Germing Ulrich, Agirre Xabier, Prosper Felipe, Aul Carlo, Killick Sally, Wainscoat James S, Schuh Anna, Boultwood Jacqueli |
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BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.
Blood 2013 Oct 122 (18): 3169-77. Damm Frederik, Chesnais Virginie, Nagata Yasunobu, Yoshida Kenichi, Scourzic Laurianne, Okuno Yusuke, Itzykson Raphael, Sanada Masashi, Shiraishi Yuichi, Gelsi-Boyer Véronique, Renneville Aline, Miyano Satoru, Mori Hiraku, Shih Lee-Yung, Park Sophie, Dreyfus François, Guerci-Bresler Agnes, Solary Eric, Rose Christian, Cheze Stéphane, Prébet Thomas, Vey Norbert, Legentil Marion, Duffourd Yannis, de Botton Stéphane, Preudhomme Claude, Birnbaum Daniel, Bernard Olivier A, Ogawa Seishi, Fontenay Michaela, Kosmider Olivi |
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Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations.
British journal of haematology 2013 Jul 162 (1): 74-86. Mallo Mar, Del Rey Mónica, Ibáñez Mariam, Calasanz M José, Arenillas Leonor, Larráyoz M José, Pedro Carmen, Jerez Andrés, Maciejewski Jaroslaw, Costa Dolors, Nomdedeu Meritxell, Diez-Campelo María, Lumbreras Eva, González-Martínez Teresa, Marugán Isabel, Such Esperanza, Cervera José, Cigudosa Juan C, Alvarez Sara, Florensa Lourdes, Hernández Jesús M, Solé France |
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Arginine homozygosity in codon 72 of p53 correlates with failure to imatinib response in chronic myeloid leukemia.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2013 Mar 67 (2): 103-7. Camelo-Santos Jeany, do Prado Barbosa Adriana, de Paula Silveira-Lacerda Elisangela, Guillo Lidia Andr |
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TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.
British journal of haematology 2013 Mar 160 (5): 660-72. Kulasekararaj Austin G, Smith Alexander E, Mian Syed A, Mohamedali Azim M, Krishnamurthy Pramila, Lea Nicholas C, Gäken Joop, Pennaneach Coralie, Ireland Robin, Czepulkowski Barbara, Pomplun Sabine, Marsh Judith C, Mufti Ghulam |
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Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.
Leukemia 2013 Feb 27 (2): 295-304. Krentz S, Hof J, Mendioroz A, Vaggopoulou R, Dörge P, Lottaz C, Engelmann J C, Groeneveld T W L, Körner G, Seeger K, Hagemeier C, Henze G, Eckert C, von Stackelberg A, Kirschner-Schwabe |
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Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2 and DNMT3A.
Blood 2013 Jan . Liang DC, Liu HC, Yang CP, Jaing TH, Hung IJ, Yeh TC, Chen SH, Hou JY, Huang YJ, Shih YS, Huang YH, Lin TH, Shih LY |
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Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia.
Haematologica 2013 Jan . Shih AH, Chung SS, Dolezal EK, Zhang SJ, Abdel-Wahab OI, Park CY, Nimer SD, Levine RL, Klimek VM |
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Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Sep 30 (27): 3376-82. Bejar Rafael, Stevenson Kristen E, Caughey Bennett A, Abdel-Wahab Omar, Steensma David P, Galili Naomi, Raza Azra, Kantarjian Hagop, Levine Ross L, Neuberg Donna, Garcia-Manero Guillermo, Ebert Benjamin |
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Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes.
Blood 2012 Apr 119 (15): 3578-84. Thol Felicitas, Kade Sofia, Schlarmann Carola, Löffeld Patrick, Morgan Michael, Krauter Jürgen, Wlodarski Marcin W, Kölking Britta, Wichmann Martin, Görlich Kerstin, Göhring Gudrun, Bug Gesine, Ottmann Oliver, Niemeyer Charlotte M, Hofmann Wolf-Karsten, Schlegelberger Brigitte, Ganser Arnold, Heuser Micha |
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Lack of association between MDM2 SNP309 and TP53 Arg72Pro polymorphisms with clinical outcomes in myelodysplastic syndrome.
Neoplasma 2012 59 (5): 530-5. Machado-Neto J A, Traina F, De Melo Campos P, Andreoli-Risso M F, Costa F F, Olalla Saad S |
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The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy.
Genes, chromosomes & cancer 2011 Oct 50 (10): 765-74. Boyd Kevin D, Ross Fiona M, Tapper William J, Chiecchio Laura, Dagrada GianPaolo, Konn Zoe J, Gonzalez David, Walker Brian A, Hockley Sarah L, Wardell Christopher P, Gregory Walter M, Child J Anthony, Jackson Graham H, Davies Faith E, Morgan Gareth J, NCRI Haematology Oncology Studies Grou |
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Clinical effect of point mutations in myelodysplastic syndromes.
The New England journal of medicine 2011 Jun 364 (26): 2496-506. Bejar Rafael, Stevenson Kristen, Abdel-Wahab Omar, Galili Naomi, Nilsson Björn, Garcia-Manero Guillermo, Kantarjian Hagop, Raza Azra, Levine Ross L, Neuberg Donna, Ebert Benjamin |
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MDM2 SNP309 and TP53 R72P associated with severe and febrile neutropenia in breast cancer patients treated with 5-FU/epirubicin/cyclophosphamide.
Breast cancer research and treatment 2011 Jun . Okishiro M, Kim SJ, Tsunashima R, Nakayama T, Shimazu K, Shimomura A, Maruyama N, Tamaki Y, Noguchi S |
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Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia.
International journal of cancer. Journal international du cancer 2011 Jan 128 (1): 233-8. Shi Jing-Yi, Ren Zhi-Hong, Jiao Bo, Xiao Run, Yun Hai-Yang, Chen Bing, Zhao Wei-Li, Zhu Qi, Chen Zhu, Chen Sai-Ju |
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The prognostic value of p53 mutation in pediatric marrow hypoplasia.
Diagnostic pathology 2011 6 (1): 58. Abo-Elwafa Hasnaa A, Attia Fadia M, Sharaf Alzahraa E |
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Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma.
Haematologica 2010 Nov 95 (11): 1973-6. Lodé Laurence, Eveillard Marion, Trichet Valérie, Soussi Thierry, Wuillème Soraya, Richebourg Steven, Magrangeas Florence, Ifrah Norbert, Campion Loïc, Traullé Catherine, Guilhot François, Caillot Denis, Marit Gérald, Mathiot Claire, Facon Thierry, Attal Michel, Harousseau Jean-Luc, Moreau Philippe, Minvielle Stéphane, Avet-Loiseau Her |
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Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients.
The pharmacogenomics journal 2010 Feb 10 (1): 54-61. Khrunin A V, Moisseev A, Gorbunova V, Limborska |
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Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
Occupational and environmental medicine 2009 Dec 66 (12): 848-53. Hosgood H D, Zhang L, Shen M, Berndt S I, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan |
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Common genetic variants in candidate genes and risk of familial lymphoid malignancies.
British journal of haematology 2009 Aug 146 (4): 418-23. Liang Xueying Sharon, Caporaso Neil, McMaster Mary Lou, Ng David, Landgren Ola, Yeager Meredith, Chanock Stephen, Goldin Lynn |
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MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility.
Blood 2008 Aug 112 (3): 741-9. Ellis Nathan A, Huo Dezheng, Yildiz Ozlem, Worrillow Lisa J, Banerjee Mekhala, Le Beau Michelle M, Larson Richard A, Allan James M, Onel Ken |
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GSTM1 and codon 72 P53 polymorphism in multiple myeloma.
Annals of hematology 2007 Nov 86 (11): 815-9. Ortega Manoela M, Honma Helen N, Zambon Lair, Lorand-Metze Irene, Costa Fernando F, De Souza Carmino A, Lima Carmen S |
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Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome.
Cancer genetics and cytogenetics 2006 Apr 166 (2): 163-5. Jekic Biljana, Novakovic Ivana, Lukovic Ljiljana, Kuzmanovic Milos, Popovic Branka, Milasin Jelena, Bunjevacki Gordana, Damnjanovic Tatjana, Cvjeticanin Suzana, Bunjevacki Ve |
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TP53 codon 72 polymorphism in patients with chronic myeloid leukemia.
Haematologica 2004 Jul 89 (7): 868-9. Bergamaschi Gaetano, Merante Serena, Orlandi Ester, Galli Anna, Bernasconi Paolo, Cazzola Mar |
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Mutations in the p53 gene in acute myeloid leukemia patients correlate with poor prognosis.
Hematology (Amsterdam, Netherlands) 2002 Feb 7 (1): 13-9. Melo Mônica B, Ahmad Nilofer N, Lima Carmen S P, Pagnano Katia B B, Bordin Silvana, Lorand-Metze Irene, SaAd Sara T O, Costa Fernando |
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[Investigation of detoxification polymorphisms genes, methylenetetrahydrofolate-reductase (MTHFR) and P53 in the radiosensitive human cells].
Radiatsionnaia biologiia, radioecologiia / Rossi?skaia akademiia nauk 0 50 (2): 128-33. Shagirova Zh M, Ushenkova L N, Mikha?lov V F, Kurbatova L A, Kuz'mina N S, Semiachkina A N, Vasil'eva I M, Mazurik V K, Zasukhina G |
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