Human Genome Epidemiology Literature Finder
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Records 1 - 30 (of 70 Records) |
| Query Trace: Genome editing[original query] |
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| Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression. Brain : a journal of neurology 2021 9 145 (2): 770-786. Li Shiwu, Li Jiao, Liu Jiewei, Wang Junyang, Li Xiaoyan, Huo Yongxia, Li Yifan, Liu Yixing, Li Ming, Xiao Xiao, Luo Xiong-Ji |
| Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos. Proceedings of the National Academy of Sciences of the United States of America 2021 5 118 (22): . Alanis-Lobato Gregorio, Zohren Jasmin, McCarthy Afshan, Fogarty Norah M E, Kubikova Nada, Hardman Emily, Greco Maria, Wells Dagan, Turner James M A, Niakan Kathy |
| Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis. Arthritis & rheumatology (Hoboken, N.J.) 2021 May . Singh Bhupinder, Maiti Guru P, Zhou Xujie, Fazel-Najafabadi Mehdi, Bae Sang-Cheol, Sun Celi, Terao Chikashi, Okada Yukinori, Heng Chua Kek, Kochi Yuta, Guthridge Joel M, Zhang Hong, Weirauch Matthew, James Judith A, Harley John B, Varshney Gaurav K, Looger Loren L, Nath Swapan |
| CRISPR-based genome editing in primary human pancreatic islet cells. Nature communications 2021 4 12 (1): 2397. Bevacqua Romina J, Dai Xiaoqing, Lam Jonathan Y, Gu Xueying, Friedlander Mollie S H, Tellez Krissie, Miguel-Escalada Irene, Bonàs-Guarch Silvia, Atla Goutham, Zhao Weichen, Kim Seung Hyun, Dominguez Antonia A, Qi Lei S, Ferrer Jorge, MacDonald Patrick E, Kim Seung |
| Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1. Investigative ophthalmology & visual science 2021 3 62 (3): 29. Xie Jiaheng, Jusuf Patricia R, Bui Bang V, Dudczig Stefanie, Sztal Tamar E, Goodbourn Patrick |
| Mouse Embryonic Fibroblasts Isolated From Nthl1 D227Y Knockin Mice Exhibit Defective DNA Repair and Increased Genome Instability. DNA repair 2021 11 109 103247. Marsden Carolyn G, Das Lipsa, Nottoli Timothy P, Kathe Scott D, Doublié Sylvie, Wallace Susan S, Sweasy Joann |
| Plasma Concentration of 12-Hydroxyeicosatetraenoic Acid, Single Nucleotide Polymorphisms of 12-Lipooxygenase Gene and Vaso-Occlusion in Sickle Cell Disease. Frontiers in genome editing 2021 10 3 722190. Duru Augustine Nwakuche, Ocheni Sunday, Ibegbulam Obike, Okpala Ihean |
| Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus. Brain : a journal of neurology 2022 9 . Wang Junyang, Liu Jiewei, Li Shiwu, Li Xiaoyan, Yang Jinfeng, Dang Xinglun, Mu Changgai, Li Yifan, Li Kaiqin, Li Jiao, Chen Rui, Liu Yixing, Huang Di, Zhang Zhijun, Luo Xiong Ji |
| A common SNP in Chrna5 enhances morphine reward in female mice. Neuropharmacology 2022 8 218 109218. Brynildsen Julia K, Yang Kechun, Lemchi Crystal, Dani John A, De Biasi Mariella, Blendy Julie |
| Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants. Genome medicine 2022 5 14 (1): 53. Chen Rui, Yang Zhihui, Liu Jiewei, Cai Xin, Huo Yongxia, Zhang Zhijun, Li Ming, Chang Hong, Luo Xiong-Ji |
| Functional genomics elucidates regulatory mechanisms of Parkinson's disease-associated variants. BMC medicine 2022 2 20 (1): 68. Chen Rui, Liu Jiewei, Li Shiwu, Li Xiaoyan, Huo Yongxia, Yao Yong-Gang, Xiao Xiao, Li Ming, Luo Xiong-Ji |
| On- and Off-Target Analyses of CRISPR-Cas12b Genome Editing Systems in Rice. The CRISPR journal 2022 11 6 (1): 62-74. Gurel Filiz, Wu Yuechao, Pan Changtian, Cheng Yanhao, Li Gen, Zhang Tao, Qi Yipi |
| CRISPR/Cas9 genome editing demonstrates functionality of the autoimmunity-associated SNP rs12946510. Biochimica et biophysica acta. Molecular basis of disease 2022 11 1869 (2): 166599. Ustiugova Alina S, Ekaterina Dvorianinova M, Nataliya Melnikova V, Alexey Dmitriev A, Dmitry Kuprash V, Marina Afanasyeva |
| Absence of copy number gain of EGFR: A possible predictive marker of long-term response to afatinib. Cancer science 2022 11 . Nakamura Tomomi, Sato Akemi, Nakashima Chiho, Abe Tomonori, Iwanaga Kentaro, Umeguchi Hitomi, Kawaguchi Atsushi, Sueoka-Aragane Nao |
| Loss of the Atrial Fibrillation-Related Gene, Zfhx3, Results in Atrial Dilation and Arrhythmias. Circulation research 2023 7 . Heather S Jameson, Alan Hanley, Matthew C Hill, Ling Xiao, Jiangchuan Ye, Aneesh Bapat, Elsa Ronzier, Amelia Weber Hall, William J Hucker, Sebastian Clauss, Miranda Barazza, Elizabeth Silber, Julie Mina, Nathan R Tucker, Robert W Mills, Jin-Tang Dong, David J Milan, Patrick T Ellin |
| A comparison of three different delivery methods for achieving CRISPR/Cas9 mediated genome editing in Cichorium intybus L. Frontiers in plant science 2023 5 14 1111110. Umberto Salvagnin, Katharina Unkel, Thorben Sprink, Paul Bundock, Robert Sevenier, Milica Bogdanovi?, Sla?ana Todorovi?, Katarina Cankar, Johanna Christina Hakkert, Elio Schijlen, Ronald Nieuwenhuis, Maria Hingsamer, Veronika Kulmer, Michael Kernitzkyi, Dirk Bosch, Stefan Martens, Mickael Maln |
| An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-?4 in female patients with Alzheimer's disease. Nature aging 2023 4 2 (7): 616-634. Yuanbing Jiang, Xiaopu Zhou, Hiu Yi Wong, Li Ouyang, Fanny C F Ip, Vicky M N Chau, Shun-Fat Lau, Wei Wu, Daniel Y K Wong, Heukjin Seo, Wing-Yu Fu, Nicole C H Lai, Yuewen Chen, Yu Chen, Estella P S Tong, , Vincent C T Mok, Timothy C Y Kwok, Kin Y Mok, Maryam Shoai, Benoit Lehallier, Patricia Morán Losada, Eleanor O'Brien, Tenielle Porter, Simon M Laws, John Hardy, Tony Wyss-Coray, Colin L Masters, Amy K Y Fu, Nancy Y |
| A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression. Nature communications 2023 3 14 (1): 1732. Li You, Li Zhiqiang, Chen Ruiling, Lian Min, Wang Hanxiao, Wei Yiran, You Zhengrui, Zhang Jun, Li Bo, Li Yikang, Huang Bingyuan, Chen Yong, Liu Qiaoyan, Lyu Zhuwan, Liang Xueying, Miao Qi, Xiao Xiao, Wang Qixia, Fang Jingyuan, Shi YongYong, Liu Xiangdong, Seldin Michael F, Gershwin M Eric, Tang Ruqi, Ma Xio |
| Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation. Nature communications 2023 12 14 (1): 7702. Elizabeth J Radford, Hong-Kee Tan, Malin H L Andersson, James D Stephenson, Eugene J Gardner, Holly Ironfield, Andrew J Waters, Daniel Gitterman, Sarah Lindsay, Federico Abascal, Iñigo Martincorena, Anna Kolesnik-Taylor, Elise Ng-Cordell, Helen V Firth, Kate Baker, John R B Perry, David J Adams, Sebastian S Gerety, Matthew E Hurl |
| Three linked variants have opposing regulatory effects on isovaleryl-CoA dehydrogenase gene expression. Human molecular genetics 2023 11 . Elizabeth A Brown, Susan Kales, Michael James Boyle, Joseph Vitti, Dylan Kotliar, Steve Schaffner, Ryan Tewhey, Pardis C Sabe |
| Genetic variation in CCDC93 is associated with elevated central systolic blood pressure, impaired arterial relaxation, and mitochondrial dysfunction. PLoS genetics 2024 9 20 (9): e1011151. Nitin Kumar, Min-Lee Yang, Pengfei Sun, Kristina L Hunker, Jianping Li, Jia Jia, Fangfang Fan, Jinghua Wang, Xianjia Ning, Wei Gao, Ming Xu, Jifeng Zhang, Lin Chang, Yuqing E Chen, Yong Huo, Yan Zhang, Santhi K Gane |
| G6pd Variant Increases the Risk of Developing VEGFR (Vascular Endothelial Growth Factor Receptor) Blocker-Induced Pulmonary Vascular Disease. Journal of the American Heart Association 2024 9 e035174. Christina Signoretti, Shun Matsumura, Samuel Fatehi, Melinee D'Silva, Rajamma Mathew, Francesca Cendali, Angelo D'Alessandro, S M Shafiqul Alam, Victor Garcia, Joseph M Miano, Sachin A Gup |
| Physiological role and mechanisms of action for a long noncoding haplotype region. bioRxiv : the preprint server for biology 2024 9 . Hong Xue, Manoj K Mishra, Yong Liu, Pengyuan Liu, Michael Grzybowski, Rajan Pandey, Kristie Usa, Mark A Vanden Avond, Niharika Bala, Abdel A Alli, Allen W Cowley, Qiongzi Qiu, Andrew S Greene, Sridhar Rao, Caitlin C O'Meara, Aron M Geurts, Mingyu Lia |
| Genome editing in K562 cells suggests a functional role for the XmnI Gg polymorphism: a widely used genetic marker in ?-thalassemia and sickle cell disease patients. Cellular and molecular biology (Noisy-le-Grand, France) 2024 8 70 (7): 230-236. Azadeh Ahmadifard, Nahal Maroofi, Maryam Maleki Tehrani, Tahere Dabestani, Masoumeh Sadat Mousavi Maleki, Sepideh Bayrami, Mehdi Ban |
| The importance of functional genomics studies in precision rheumatology. Best practice & research. Clinical rheumatology 2024 8 101988. Ana Pires Piedade, Jake Butler, Stephen Eyre, Gisela Oroz |
| Saturation genome editing maps the functional spectrum of pathogenic VHL alleles. Nature genetics 2024 7 . Megan Buckley, Chloé Terwagne, Athina Ganner, Laura Cubitt, Reid Brewer, Dong-Kyu Kim, Christina M Kajba, Nicole Forrester, Phoebe Dace, Joachim De Jonghe, Scott T C Shepherd, Chelsea Sawyer, Mairead McEwen, Sven Diederichs, Elke Neumann-Haefelin, Samra Turajlic, Evgueni A Ivakine, Gregory M Findl |
| CRISPR/Cas9 gene editing clarifies the role of CD33 SNP rs12459419 in gemtuzumab ozogamicin-mediated cytotoxicity. International journal of hematology 2024 6 . Shuki Oya, Hidetoshi Ozawa, Takayuki Nakamura, Akira Mori, Sorahiko Ochi, Yoshimi Maehiro, Masahiro Umeda, Yusuke Takaki, Toshinobu Fukuyama, Yoshitaka Yamasaki, Maki Yamaguchi, Kazutoshi Aoyama, Fumihiko Mouri, Koji Nagafu |
| Optimised, Broad NGS Panel for Inherited Eye Diseases to Diagnose 1000 Patients in Poland. Biomedicines 2024 6 12 (6): . Ewa Matczy?ska, Marta Be?-Gajowniczek, Larysa Sivitskaya, El?bieta Gregorczyk, Przemys?aw ?yszkiewicz, Robert Szyma?czak, Maria J?drzejowska, Edward Wyl?ga?a, Maciej R Krawczy?ski, S?awomir Teper, Anna Boguszewska-Chachuls |
| Discovery and engineering of ChCas12b for precise genome editing. Science bulletin 2024 6 . Jingjing Wei, Jingtong Liu, Yuwen Tian, Ziwen Wang, Linghui Hou, Yuan Yang, Chen Tao, Miaomiao Li, Bao-Qing Gao, Huanyu Zhou, Xixi Zheng, Junnan Tang, Song Gao, Li Yang, Renjie Chai, Yongming Wa |
| Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk. European heart journal 2024 1 . Émilie Gobeil, Jérôme Bourgault, Patricia L Mitchell, Ursula Houessou, Eloi Gagnon, Arnaud Girard, Audrey Paulin, Hasanga D Manikpurage, Valérie Côté, Christian Couture, Simon Marceau, Yohan Bossé, Sébastien Thériault, Patrick Mathieu, Marie-Claude Vohl, André Tchernof, Benoit J Arsenau |
- Page last reviewed:Feb 1, 2024
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