HuGE Literature Finder
Records 1-30
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Genetic polymorphisms of TP53 (rs1042522) and MDM2 (rs2279744) and colorectal cancer risk: An updated meta-analysis based on 59 case-control studies.
Gene 2020 Jan 734 144391. Elshazli Rami M, Toraih Eman A, Elgaml Abdelaziz, Kandil Emad, Fawzy Manal |
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Mucinous adenocarcinoma of the colon and rectum: A genomic analysis.
Journal of surgical oncology 2019 Nov . Reynolds Ian S, O'Connell Emer, Fichtner Michael, McNamara Deborah A, Kay Elaine W, Prehn Jochen H M, Furney Simon J, Burke John |
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Recurrence risk evaluation in T1N1M0/T2N0M0/T3N0M0 gastric cancer with TP53 codon 72 polymorphisms.
Journal of surgical oncology 2019 Oct . Ohmori Yukimi, Nomura Takashi, Fukushima Norimasa, Takahashi Fumiaki, Iwaya Takeshi, Koeda Keisuke, Nishizuka Satoshi S, |
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Molecular and clinicopathological analyses of esophageal carcinosarcoma with special reference to morphological change.
Virchows Archiv : an international journal of pathology 2019 Aug . Tsuyama Sho, Saito Tsuyoshi, Akazawa Yoichi, Yanai Yuka, Yatagai Noboru, Akaike Keisuke, Hayashi Takuo, Suehara Yoshiyuki, Takahashi Fumiyuki, Takamochi Kazuya, Hashimoto Takashi, Kajiyama Yoshiaki, Tsurumaru Masahiko, Fukunaga Tetsu, Yao Takas |
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Histologic features and genomic alterations of primary colorectal adenocarcinoma predict growth patterns of liver metastasis.
World journal of gastroenterology 2019 Jul 25 (26): 3408-3425. Wu Jing-Bo, Sarmiento Ali Lopez, Fiset Pierre-Olivier, Lazaris Anthula, Metrakos Peter, Petrillo Stephanie, Gao Zu-H |
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Necessity of Genetic Evaluation of Metachronous Metastases of Colorectal Cancer: Quantitative Analysis of Genetic Discordance Between Metachronous Metastases and Radically Resected Primary Colorectal Cancers Using Next-Generation Sequencing.
Diseases of the colon and rectum 2019 Jul 62 (7): 832-839. Lee Kyung Ha, Kim Jin Soo, Kim Ji Ye |
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Analysis of KRAS, NRAS, BRAF, PIK3CA and TP53 mutations in a large prospective series of locally advanced rectal cancer patients.
International journal of cancer 2019 Jun . Sclafani Francesco, Hulkki Wilson Sanna, Cunningham David, Gonzalez De Castro David, Kalaitzaki Eleftheria, Begum Ruwaida, Wotherspoon Andrew, Capdevila Jaume, Glimelius Bengt, Roselló Susana, Thomas Janet, Tait Daina, Brown Gina, Oates Jacqui, Chau I |
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Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer.
BMC cancer 2019 Jun 19 (1): 644. Cavagnari Mariana Abe Vicente, Silva Tiago Donizetti, Pereira Marco Antonio Haddad, Sauer Luísa Jacques, Shigueoka David, Saad Sarhan Sydney, Barão Katia, Ribeiro Carla Caroline Dias, Forones Nora Manouki |
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Association of pathway mutation with survival after recurrence in colorectal cancer patients treated with adjuvant fluoropyrimidine and oxaliplatin chemotherapy.
BMC cancer 2019 May 19 (1): 421. Lee Dae-Won, Han Sae-Won, Cha Yongjun, Bae Jeong Mo, Kim Hwang-Phill, Lyu Jaemyun, Han Hyojun, Kim Hyoki, Jang Hoon, Bang Duhee, Won Jae-Kyung, Jeong Seung-Yong, Park Kyu Joo, Kang Gyeong Hoon, Kim Tae-Y |
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Targeted next generation sequencing reveals a common genetic pathway for colorectal cancers with chromosomal instability and those with microsatellite and chromosome stability.
Pathology, research and practice 2019 May 152445. Ham-Karim Hersh A, Ebili Henry O, Bradshaw Kirsty, Richman Susan D, Fadhil Wakkas, Domingo Enric, Tomlinson Ian, Ilyas Mohamm |
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Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer: Two case reports.
Medicine 2019 Mar 98 (12): e14781. Okada Satoshi, Hata Keisuke, Kawai Kazushige, Yamamoto Yoko, Tanaka Toshiaki, Nishikawa Takeshi, Sasaki Kazuhito, Kaneko Manabu, Emoto Shigenobu, Murono Koji, Nozawa Hiroa |
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Can we classify ampullary tumours better? Clinical, pathological and molecular features. Results of an AGEO study.
British journal of cancer 2019 Mar . Perkins Geraldine, Svrcek Magali, Bouchet-Doumenq Cecile, Voron Thibault, Colussi Orianne, Debove Clotilde, Merabtene Fatiha, Dumont Sylvie, Sauvanet Alain, Hammel Pascal, Cros Jerome, André Thierry, Bachet Jean-Baptiste, Bardier Armelle, Douard Richard, Meatchi Tchao, Peschaud Frederique, Emile Jean-Francois, Cojean-Zelek Isabelle, Laurent-Puig Pierre, Taieb Juli |
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DNA variants in Helicobacter pylori infected patients with chronic gastritis, dysplasia and gastric cancer.
Advances in medical sciences 2019 Mar 64 (1): 79-84. Hnatyszyn Andrzej, Szalata Marlena, Skrzypczak-Zielinska Marzena, Wielgus Karolina, Stanczyk Jerzy, Dziuba Ireneusz, Mikstacki Adam, Dobrowolska Agnieszka, Waszak Malgorzata, Hnatyszyn Piotr Tomasz, Slomski Rysza |
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Intake of Red and Processed Meat, Use of Non-Steroid Anti-Inflammatory Drugs, Genetic Variants and Risk of Colorectal Cancer: A Prospective Study of the Danish "Diet, Cancer and Health" Cohort.
International journal of molecular sciences 2019 Mar 20 (5): . Andersen Vibeke, Halekoh Ulrich, Tjønneland Anne, Vogel Ulla, Kopp Tine Isk |
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p53 expression status is associated with cancer-specific survival in stage III and high-risk stage II colorectal cancer patients treated with oxaliplatin-based adjuvant chemotherapy.
British journal of cancer 2019 Mar . Oh Hyeon Jeong, Bae Jeong Mo, Wen Xianyu, Jung Seorin, Kim Younghoon, Kim Kyung Ju, Cho Nam-Yun, Kim Jung Ho, Han Sae-Won, Kim Tae-You, Kang Gyeong Ho |
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Targeted next-generation sequencing of well-differentiated rectal, gastric, and appendiceal neuroendocrine tumors to identify potential targets.
Human pathology 2019 Mar . Park Ha Young, Kwon Mi Jung, Kang Ho Suk, Kim Yun Joong, Kim Nan Young, Kim Min Jeong, Min Kyueng-Whan, Choi Kyung Chan, Nam Eun Sook, Cho Seong Jin, Park Hye-Rim, Min Soo Kee, Seo Jinwon, Choe Ji-Young, Lee Hye Kyu |
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Association of genetic variants in CHEK2 with oesophageal squamous cell carcinoma in the South African Black population.
Carcinogenesis 2019 Feb . Chen Wenlong C, Bye Hannah, Matejcic Marco, Amar Ariella, Govender Dhiren, Khew Yee Wen, Beynon Victoria, Kerr Robyn, Singh Elvira, Prescott Natalie J, Lewis Cathryn M, Babb de Villiers Chantal, Parker M Iqbal, Mathew Christopher |
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Identification of DNA mutations in gastric washes from gastric adenocarcinoma patients: possible implications for liquid biopsies and patient follow-up.
International journal of cancer 2019 Feb . Pizzi Melissa Pool, Bartelli Thais Fernanda, Pelosof Adriane Graicer, Carioca-Freitas Helano, Begnami Maria Dirlei, de Abrantes Lais Lie Senda, Sztokfisz Claudia, Valieris Renan, Knebel Franciele Hinterholz, Vaz Coelho Luiz Gonzaga, da Costa Wilson Luiz, Coimbra Felipe Jf, da Silva Israel Tojal, de Amorim Maria Galli, Nunes Diana Noronha, Dias-Neto Emmanu |
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Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.
Cancer medicine 2019 Jan 8 (1): 408-417. Osumi Hiroki, Shinozaki Eiji, Takeda Yoshinori, Wakatsuki Takeru, Ichimura Takashi, Saiura Akio, Yamaguchi Kensei, Takahashi Shunji, Noda Tetsuo, Zembutsu Hitos |
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Immune checkpoint blockade resistance-related B2M hotspot mutations in microsatellite-unstable colorectal carcinoma.
Pathology, research and practice 2019 Jan 215 (1): 209-214. Yeon Yeon Su, Jung Seung-Hyun, Jo Yun Sol, Choi Eun Ji, Kim Min Sung, Chung Yeun-Jun, Lee Sug Hyu |
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Near-comprehensive resequencing of cancer-associated genes in surgically resected metastatic liver tumors of gastric cancer.
The American journal of pathology 2019 Jan . Ikari Naoki, Serizawa Akiko, Mitani Shohei, Yamamoto Masakazu, Furukawa To |
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Clinicopathological characterization of SMAD4-mutated intestinal adenocarcinomas: A case-control study.
PloS one 2019 14 (2): e0212142. Liao Xiaoyan, Hao Yansheng, Zhang Xiaofei, Ward Stephen, Houldsworth Jane, Polydorides Alexandros D, Harpaz No |
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High Frequency of KRAS Codon 146 and FBXW7 Mutations in Thai Patients with Stage II-III Colon Cancer.
Asian Pacific journal of cancer prevention : APJCP 2019 08 20 (8): 2319-2326. Korphaisarn Krittiya, Pongpaibul Ananya, Roothumnong Ekkapong, Pongsuktavorn Khontawan, Thamlikitkul Lucksamon, Anekpuritanang Tauangtham, Poungvarin Naravat, Thongnoppakhun Wanna, Pithukpakorn Man |
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Positive effect of single nucleotide RAD51 135G>C polymorphism and low Ku70 protein expression on female rectal cancer patients survival after preoperative radiotherapy.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2018 Oct . Gasinska Anna, Biesaga Beata, Widla Anna Janecka, Darasz Zbigni |
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Association between p53 Arg72Pro polymorphism and colorectal cancer risk in Asian population: a meta-analysis.
Current problems in cancer 2018 Sep . Zhang Yuyang, Zhang Dan, Zhao Lin, Sun Lili, Dong Qiguan, Cheng Li, Cheng Rix |
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Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine.
Virchows Archiv : an international journal of pathology 2018 Sep . Simbolo Michele, Vicentini Caterina, Mafficini Andrea, Fassan Matteo, Pedron Serena, Corbo Vincenzo, Mastracci Luca, Rusev Borislav, Pedrazzani Corrado, Landoni Luca, Grillo Federica, Cingarlini Sara, Rindi Guido, Luchini Claudio, Scarpa Aldo, Lawlor Rita |
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Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity.
JCI insight 2018 Aug 3 (15): . Fischer Nicholas W, Prodeus Aaron, Gariépy Je |
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[Exome sequencing of gastric cancers screened the differences of clinicopathological phenotypes between the mutant and the wide-type of frequently mutated genes].
Zhonghua yi xue za zhi 2018 Jul 98 (28): 2242-2245. Cong T, Liu G X, Cui J X, Zhang K C, Chen Z D, Chen L, Wei B, Huang X |
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Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Clinical colorectal cancer 2018 Jul . Khan Maliha, Loree Jonathan M, Advani Shailesh M, Ning Jing, Li Wen, Pereira Allan A L, Lam Michael, Raghav Kanwal, Morris Van K, Broaddus Russell, Maru Dipen, Overman Michael J, Kopetz Sco |
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Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Annals of surgical oncology 2018 Jul 25 (7): 2027-2033. van Beek Elke J A H, Hernandez Jonathan M, Goldman Debra A, Davis Jeremy L, McLaughlin Kaitlin, Ripley R Taylor, Kim Teresa S, Tang Laura H, Hechtman Jaclyn F, Zheng Jian, Capanu Marinela, Schultz Nikolaus, Hyman David M, Ladanyi Marc, Berger Michael F, Solit David B, Janjigian Yelena Y, Strong Vivian |
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Circulating tumor DNA detectable in early- and late-stage colorectal cancer patients.
Bioscience reports 2018 Jun . Yang Ying-Chi, Wang Dong, Jin Lan, Yao Hong-Wei, Zhang Jing-Hui, Wang Jin, Zhao Xiao-Mu, Shen Chun-Ying, Chen Wei, Wang Xue-Liang, Shi Rong, Chen Si-Yi, Zhang Zhong-T |
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Metabolic Imaging Phenotype Using Radiomics of [ 18 F]FDG PET/CT Associated with Genetic Alterations of Colorectal Cancer.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2018 Jun . Chen Shang-Wen, Shen Wei-Chih, Chen William Tzu-Liang, Hsieh Te-Chun, Yen Kuo-Yang, Chang Jan-Gowth, Kao Chia-Hu |
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Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Medical oncology (Northwood, London, England) 2018 May 35 (7): 101. Papaxoinis George, Kotoula Vassiliki, Giannoulatou Eleni, Koliou Georgia-Angeliki, Karavasilis Vasilios, Lakis Sotirios, Koureas Andreas, Bobos Mattheos, Chalaralambous Elpida, Daskalaki Emily, Chatzopoulos Kyriakos, Tsironis George, Pazarli Elisavet, Chrisafi Sofia, Samantas Epaminontas, Kaklamanos Ioannis G, Varthalitis Ioannis, Konstantara Athina, Syrigos Konstantinos N, Pentheroudakis George, Pectasides Dimitrios, Fountzilas Geor |
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Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer.
Experimental & molecular medicine 2018 Apr 50 (4): 6. Choi Ji-Hye, Kim Young-Bae, Ahn Ji Mi, Kim Min Jae, Bae Won Jung, Han Sang-Uk, Woo Hyun Goo, Lee Dake |
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Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Journal of the National Cancer Institute 2018 Apr . Loree Jonathan M, Bailey Ann M, Johnson Amber M, Yu Yao, Wu Wenhui, Bristow Christopher A, Davis Jennifer S, Shaw Kenna R, Broaddus Russell, Banks Kimberly C, Lanman Richard B, Meric-Bernstam Funda, Overman Michael J, Kopetz Scott, Raghav Kanw |
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Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Virchows Archiv : an international journal of pathology 2018 Apr . Wang Yajian, Liu Haijing, Hou Yingyong, Zhou Xiaoyan, Liang Li, Zhang Zhihong, Shi Huaiyin, Xu Sanpeng, Hu Peizhen, Zheng Zuyu, Liu Rui, Tang Tingdong, Ye Feng, Liang Zhiyong, Bu Ho |
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Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer.
PLoS genetics 2018 Apr 14 (4): e1007355. Paulo Paula, Maia Sofia, Pinto Carla, Pinto Pedro, Monteiro Augusta, Peixoto Ana, Teixeira Manuel |
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APC:T1556fs and STK11 mutations in duodenal adenomas and adenocarcinomas.
Surgery today 2018 Mar . Kojima Yohei, Ohtsuka Kouki, Ohnishi Hiroaki, Abe Nobutsugu, Furuse Junji, Watanabe Takashi, Sugiyama Masano |
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Exome-wide somatic mutation characterization of small bowel adenocarcinoma.
PLoS genetics 2018 Mar 14 (3): e1007200. Hänninen Ulrika A, Katainen Riku, Tanskanen Tomas, Plaketti Roosa-Maria, Laine Riku, Hamberg Jiri, Ristimäki Ari, Pukkala Eero, Taipale Minna, Mecklin Jukka-Pekka, Forsström Linda M, Pitkänen Esa, Palin Kimmo, Välimäki Niko, Mäkinen Netta, Aaltonen Lauri |
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Genetic polymorphisms of TP53 Arg72Pro and Pro47Ser among Egyptian patients with colorectal carcinoma.
Archives of physiology and biochemistry 2018 Mar 1-8. Elsaid Afaf, Zahran Rasha, Elshazli Rami, El-Sayed Ahmed, Abou Samra Marwa, El-Tarapely Fatma, Abdel-Malak Camel |
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Mutation analysis of adenomas and carcinomas of the colon: early and late drivers.
Genes, chromosomes & cancer 2018 Mar . Wolff Roger K, Hoffman Michael D, Wolff Erica C, Herrick Jennifer S, Sakoda Lori C, Samowitz Wade, Slattery Martha |
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The Molecular Landscape of Synchronous Colorectal Cancer Reveals Genetic Heterogeneity.
Carcinogenesis 2018 Mar . Wang Xiangfeng, Fang Hu, Cheng Yong, Li Lin, Sun Xiaohui, Fu Tao, Huang Peide, Zhang Anping, Feng Zhimin, Li Chunxue, Huang Xuanlin, Li Guangyan, Du Peina, Yang Huanming, Fang Xiaodong, Li Fan, Gao Qiang, Liu Baoh |
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World journal of gastroenterology 2018 Feb 24 (5): 631-640. Li A-Jian, Li Hua-Guang, Tang Er-Jiang, Wu Wei, Chen Ying, Jiang Hui-Hong, Lin Mou-Bin, Yin |
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Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing.
Neoplasia (New York, N.Y.) 2018 Feb 20 (3): 256-262. Shajani-Yi Zahra, de Abreu Francine B, Peterson Jason D, Tsongalis Gregory |
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A mutational signature associated with alcohol consumption and prognostically significantly mutated driver genes in esophageal squamous cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Jan . Li X C, Wang M Y, Yang M, Dai H J, Zhang B F, Wang W, Chu X L, Wang X, Zheng H, Niu R F, Zhang W, Chen K |
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Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2018 Jan . Jesinghaus Moritz, Konukiewitz Björn, Foersch Sebastian, Stenzinger Albrecht, Steiger Katja, Muckenhuber Alexander, Groß Claudia, Mollenhauer Martin, Roth Wilfried, Detlefsen Sönke, Weichert Wilko, Klöppel Günter, Pfarr Nicole, Schlitter Anna Melis |
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Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Jan 29 (1): 230-236. Moorcraft S Y, Gonzalez de Castro D, Cunningham D, Jones T, Walker B A, Peckitt C, Yuan L C, Frampton M, Begum R, Eltahir Z, Wotherspoon A, Teixeira Mendes L S, Hulkki Wilson S, Gillbanks A, Baratelli C, Fotiadis N, Patel A, Braconi C, Valeri N, Gerlinger M, Rao S, Watkins D, Chau I, Starling |
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Mutations of key driver genes in colorectal cancer progression and metastasis.
Cancer metastasis reviews 2018 Jan . Huang Dongdong, Sun Wenjie, Zhou Yuwei, Li Peiwei, Chen Fang, Chen Hanwen, Xia Dajing, Xu Enping, Lai Maode, Wu Yihua, Zhang Hong |
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Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Molecular cancer 2018 12 17 (1): 176. Chen Erfei, Yang Fangfang, He Hongjuan, Li Qiqi, Zhang Wei, Xing Jinliang, Zhu Ziqing, Jiang Jingjing, Wang Hua, Zhao Xiaojuan, Liu Ruitao, Lei Lei, Dong Jing, Pei Yuchen, Yang Ying, Pan Junqiang, Zhang Pan, Liu Shuzhen, Du Le, Zeng Yuan, Yang J |
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HPV Status and Mutation Analysis Using Multiparallel Sequencing in Distal Oesophageal and Gastro-oesophageal Junction Adenocarcinomas.
Folia biologica 2018 64 (2): 41-45. Vošmik M, Vošmiková H, Sieglová K, Sirák I, Laco J, Ryška A, Petera J, Melichar B, Soumarová |
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Sidedness and TP53 mutations impact OS in anti-EGFR but not anti-VEGF treated mCRC - an analysis of the KRAS registry of the AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie).
BMC cancer 2018 01 18 (1): 11. Huemer Florian, Thaler Josef, Piringer Gudrun, Hackl Hubert, Pleyer Lisa, Hufnagl Clemens, Weiss Lukas, Greil Richa |
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Analysis of 12 variants in the development of gastric and colorectal cancers.
World journal of gastroenterology 2017 Dec 23 (48): 8533-8543. Cavalcante Giovanna C, Amador Marcos At, Ribeiro Dos Santos André M, Carvalho Darlen C, Andrade Roberta B, Pereira Esdras Eb, Fernandes Marianne R, Costa Danielle F, Santos Ney Pc, Assumpção Paulo P, Ribeiro Dos Santos Ândrea, Santos Sidn |
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Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Molecular carcinogenesis 2017 Dec . Sugai Tamotsu, Takahashi Yayoi, Eizuka Makoto, Sugimoto Ryo, Fujita Yasuko, Habano Wataru, Otsuka Kouki, Sasaki Akira, Yamamoto Eiichiro, Matsumoto Takayuki, Suzuki Hiro |
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TP53 Gene Pro72Arg (rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population
Asian Pacific journal of cancer prevention : APJCP 2017 Dec 18 (12): 3423-3427. Asadi Milad, Shanehbandi Dariush, Zarintan Armin, Pedram Negar, Baradaran Behzad, Zafari Venus, Shirmohamadi Masoud, Hashemzadeh Shahriy |
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Study of the Association of Polymorphisms of p53 and p21 with the Risk of Development of Stomach Cancer.
Bulletin of experimental biology and medicine 2017 Nov 164 (1): 95-98. Dmitrieva A I, Serebryakova V A, Rakitin S S, Kudyakov L A, Novitskii V V, Yankovich K I, Sevostyanova N |
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Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features.
World journal of gastroenterology 2017 Oct 23 (37): 6854-6867. Marques Diego, Ferreira-Costa Layse Raynara, Ferreira-Costa Lorenna Larissa, Correa Romualdo da Silva, Borges Aline Maciel Pinheiro, Ito Fernanda Ribeiro, Ramos Carlos Cesar de Oliveira, Bortolin Raul Hernandes, Luchessi André Ducati, Ribeiro-Dos-Santos Ândrea, Santos Sidney, Silbiger Vivian Noguei |
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Genome-wide association study identified copy number variants associated with sporadic colorectal cancer risk.
Journal of medical genetics 2017 Oct . Thean Lai Fun, Low Yee Syuen, Lo Michelle, Teo Yik-Ying, Koh Woon-Puay, Yuan Jian-Min, Chew Min Hoe, Tang Choong Leong, Cheah Peh Ye |
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Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Clinical colorectal cancer 2017 Oct . Chiu Joanne W, Krzyzanowska Monika K, Serra Stefano, Knox Jennifer J, Dhani Neesha C, Mackay Helen, Hedley David, Moore Malcolm, Liu Geoffrey, Burkes Ronald L, Brezden-Masley Christine, Roehrl Michael H, Craddock Kenneth J, Tsao Ming-Sound, Zhang Tong, Yu Celeste, Kamel-Reid Suzanne, Siu Lillian L, Bedard Philippe L, Chen Eric |
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Clinicopathologic and Molecular Characteristics of Synchronous Colorectal Carcinoma With Mismatch Repair Deficiency.
The American journal of surgical pathology 2017 Sep . Nakano Kayoko, Yamamoto Hidetaka, Fujiwara Minako, Koga Yutaka, Tsuruta Shinichi, Ihara Eikichi, Oki Eiji, Nakamura Masafumi, Ogawa Yoshihiro, Oda Yoshin |
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Gastric Poorly Cohesive Carcinoma: A correlative study of mutational signatures and prognostic significance based on histopathologic subtypes.
Histopathology 2017 Sep . Kwon Chae Hwa, Kim Young Keum, Lee Sojeong, Kim Ahrong, Park Hye Ji, Choi Yuri, Won Yeo Jin, Park Do Youn, Lauwers Gregory |
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Tumor heterogeneity predicts metastatic potential in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep . Joung Je-Gun, Oh Bo Young, Hong Hye Kyung, AlKhalidi Hisham, Al-Alem Faisal, Lee Hae-Ock, Bae Joon Seol, Kim Jinho, Cha Hong-Ui, Alotaibi Maram, Cho Yong Beom, Hassanain Mazen, Lee Woo Yong, Park Woong-Ya |
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Association of Intron Microsatellite Instability and Exon Mutational Profile of TP53 in Human Gastric Cancers.
Anticancer research 2017 Aug 37 (8): 4507-4514. Huo Xueyun, Xiao Xiaoqin, Zhang Shuangyue, Zhou Deshan, Chen Zhenw |
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Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases.
Annals of surgery 2017 Aug . Chun Yun Shin, Passot Guillaume, Yamashita Suguru, Nusrat Maliha, Katsonis Panagiotis, Loree Jonathan M, Conrad Claudius, Tzeng Ching-Wei D, Xiao Lianchun, Aloia Thomas A, Eng Cathy, Kopetz Scott E, Lichtarge Olivier, Vauthey Jean-Nicol |
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Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Jul . Singhi Aatur D, Arnold Christina A, Lam-Himlin Dora M, Nikiforova Marina N, Voltaggio Lysandra, Canto Marcia I, McGrath Kevin M, Montgomery Elizabeth |
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Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Molecular oncology 2017 Jun . Dienstmann Rodrigo, Elez Elena, Argiles Guillem, Matos Ignacio, Sanz-Garcia Enrique, Ortiz Carolina, Macarulla Teresa, Capdevila Jaume, Alsina Maria, Sauri Tamara, Verdaguer Helena, Vilaro Marta, Ruiz-Pace Fiorella, Viaplana Cristina, Garcia Ariadna, Landolfi Stefania, Palmer Hector G, Nuciforo Paolo, Rodon Jordi, Vivancos Ana, Tabernero Jos |
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Human papillomavirus infection increases the chemoradiation response of esophageal squamous cell carcinoma based on P53 mutation.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2017 Jun . Zhang Dakai, Zhang Wei, Liu Wenzhi, Mao Yu, Fu Zhanzhao, Liu Jia, Huang Wei, Zhang Zicheng, An Dianzheng, Li Baoshe |
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Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma.
Oncotarget 2017 Jun 8 (26): 42487-42494. Vakiani Efsevia, Shah Ronak H, Berger Michael F, Makohon-Moore Alvin P, Reiter Johannes G, Ostrovnaya Irina, Attiyeh Marc A, Cercek Andrea, Shia Jinru, Iacobuzio-Donahue Christine A, Solit David B, Weiser Martin |
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Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.
British journal of cancer 2017 Jun 116 (12): 1652-1659. Gray Ronan T, Loughrey Maurice B, Bankhead Peter, Cardwell Chris R, McQuaid Stephen, O'Neill Roisin F, Arthur Kenneth, Bingham Victoria, McGready Claire, Gavin Anna T, James Jacqueline A, Hamilton Peter W, Salto-Tellez Manuel, Murray Liam J, Coleman Helen |
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Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
British journal of cancer 2017 Jun 117 (1): 136-143. Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaet |
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Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Cancer 2017 May . Lee Dae-Won, Han Sae-Won, Cha Yongjun, Bae Jeong Mo, Kim Hwang-Phill, Lyu Jaemyun, Han Hyojun, Kim Hyoki, Jang Hoon, Bang Duhee, Huh Iksoo, Park Taesung, Won Jae-Kyung, Jeong Seung-Yong, Park Kyu Joo, Kang Gyeong Hoon, Kim Tae-Y |
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Association of TP53 codon 72 and CDH1 genetic polymorphisms with colorectal cancer risk in Bangladeshi population.
Cancer epidemiology 2017 May 49 46-52. Rivu Sanzana Fareen, Apu Mohd Nazmul Hasan, Shabnaz Samia, Nahid Noor Ahmed, Islam Md Reazul, Al-Mamun Mir Md Abdullah, Nahar Zabun, Rabbi Sikder Nahidul Islam, Ahmed Maizbha Uddin, Islam Mohammad Safiqul, Hasnat Ab |
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Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 2017 May 28 (5): 1015-1022. Suenaga M, Schirripa M, Cao S, Zhang W, Yang D, Murgioni S, Rossini D, Marmorino F, Mennitto A, Ning Y, Okazaki S, Berger M D, Miyamoto Y, Gopez R, Barzi A, Yamaguchi T, Loupakis F, Lenz H |
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p16 gene silencing along with p53 single-nucleotide polymorphism and risk of esophageal cancer in Northeast India.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May 39 (5): 1010428317698384. Das Mandakini, Sharma Santanu Kumar, Sekhon Gaganpreet Singh, Mahanta Jagadish, Phukan Rup Kumar, Jalan Bimal Kum |
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Mutational profile of TP53 in esophageal squamous cell carcinoma associated with chagasic megaesophagus.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2017 Apr 30 (4): 1-9. Lacerda C F, Cruvinel-Carloni A, de Oliveira A T Torres, Scapulatempo-Neto C, López R V M, Crema E, Adad S J, Rodrigues M A M, Henry M A C A, Guimarães D P, Reis R |
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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.
European journal of cancer (Oxford, England : 1990) 2017 Mar 76 144-151. de Jonge Maja, de Weger Vincent A, Dickson Mark A, Langenberg Marlies, Le Cesne Axel, Wagner Andrew J, Hsu Karl, Zheng Wei, Macé Sandrine, Tuffal Gilles, Thomas Koruth, Schellens Jan H |
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Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar 39 (3): 1010428317692246. Kleist Britta, Meurer Thuja, Poetsch Micae |
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Relevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype.
Oncotarget 2017 Mar . Carrera-Lasfuentes Patricia, Lanas Angel, Bujanda Luis, Strunk Mark, Quintero Enrique, Santolaria Santos, Benito Rafael, Sopeña Federico, Piazuelo Elena, Thomson Concha, Pérez-Aisa Angeles, Nicolás-Pérez David, Hijona Elizabeth, Espinel Jesús, Campo Rafael, Manzano Marisa, Geijo Fernando, Pellise María, Zaballa Manuel, González-Huix Ferrán, Espinós Jorge, Titó Llúcia, Barranco Luis, D'Amato Mauro, García-González María Asunci |
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Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 2017 Feb . Suenaga M, Schirripa M, Cao S, Zhang W, Yang D, Murgioni S, Rossini D, Marmorino F, Mennitto A, Ning Y, Okazaki S, Berger M D, Miyamoto Y, Gopez R, Barzi A, Yamaguch T, Loupakis F, Lenz H |
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Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Feb 39 (2): 1010428317692265. Jauhri Mayank, Bhatnagar Akanksha, Gupta Satish, Bp Manasa, Minhas Sachin, Shokeen Yogender, Aggarwal Shy |
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The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma.
Oncotarget 2017 Feb . Stein Caleb K, Pawlyn Charlotte, Chavan Shweta, Rasche Leo, Weinhold Niels, Corken Adam, Buros Amy, Sonneveld Pieter, Jackson Graham H, Landgren Ola, Mughal Tariq, He Jie, Barlogie Bart, Leif Bergsagel P, Davies Faith E, Walker Brian A, Morgan Gareth |
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BRAF-Mutated Colorectal Cancer Exhibits Distinct Clinicopathological Features from Wild-Type BRAF-Expressing Cancer Independent of the Microsatellite Instability Status.
Journal of Korean medical science 2017 Jan 32 (1): 38-46. Jang Min Hye, Kim Sehun, Hwang Dae Yong, Kim Wook Youn, Lim So Dug, Kim Wan Seop, Hwang Tea Sook, Han Hye Seu |
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DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Nature communications 2017 Jan 8 14093. Mamlouk Soulafa, Childs Liam Harold, Aust Daniela, Heim Daniel, Melching Friederike, Oliveira Cristiano, Wolf Thomas, Durek Pawel, Schumacher Dirk, Bläker Hendrik, von Winterfeld Moritz, Gastl Bastian, Möhr Kerstin, Menne Andrea, Zeugner Silke, Redmer Torben, Lenze Dido, Tierling Sascha, Möbs Markus, Weichert Wilko, Folprecht Gunnar, Blanc Eric, Beule Dieter, Schäfer Reinhold, Morkel Markus, Klauschen Frederick, Leser Ulf, Sers Christi |
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KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis.
Oncotarget 2017 Jan . Du Lijun, Kim John J, Shen Jinhua, Chen Binrui, Dai Ni |
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Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations.
Nature communications 2017 11 8 (1): 1533. Deng Jiaying, Chen Hu, Zhou Daizhan, Zhang Junhua, Chen Yun, Liu Qi, Ai Dashan, Zhu Hanting, Chu Li, Ren Wenjia, Zhang Xiaofei, Xia Yi, Sun Menghong, Zhang Huiwen, Li Jun, Peng Xinxin, Li Liang, Han Leng, Lin Hui, Cai Xiujun, Xiang Jiaqing, Chen Shufeng, Sun Yihua, Zhang Yawei, Zhang Jie, Chen Haiquan, Zhang Shijian, Zhao Yi, Liu Yun, Liang Han, Zhao Kuai |
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Low Variability and Stable Frequency of Common Haplotypes of the TP53 Gene Region in Colorectal Cancer Patients in a Slovak Population.
Anticancer research 2017 04 37 (4): 1901-1907. Škere?ová Mária, Halašová Erika, Matáková Tatiana, Jesenská ?ubica, Jure?eková Jana, Šarlinová Miroslava, ?ierny Daniel, Dobrota Duš |
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P53 deregulation in Epstein-Barr virus-associated gastric cancer.
Cancer letters 2017 09 404 37-43. Ribeiro Joana, Malta Mariana, Galaghar Ana, Silva Fernanda, Afonso Luís Pedro, Medeiros Rui, Sousa Hu |
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Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Gastroenterology 2017 08 153 (2): 536-549.e26. Cho Soo Young, Park Jun Won, Liu Yang, Park Young Soo, Kim Ju Hee, Yang Hanna, Um Hyejin, Ko Woo Ri, Lee Byung Il, Kwon Sun Young, Ryu Seung Wan, Kwon Chae Hwa, Park Do Youn, Lee Jae-Hyuk, Lee Sang Il, Song Kyu Sang, Hur Hoon, Han Sang-Uk, Chang Heekyung, Kim Su-Jin, Kim Byung-Sik, Yook Jeong-Hwan, Yoo Moon-Won, Kim Beom-Su, Lee In-Seob, Kook Myeong-Cherl, Thiessen Nina, He An, Stewart Chip, Dunford Andrew, Kim Jaegil, Shih Juliann, Saksena Gordon, Cherniack Andrew D, Schumacher Steven, Weiner Amaro-Taylor, Rosenberg Mara, Getz Gad, Yang Eun Gyeong, Ryu Min-Hee, Bass Adam J, Kim Hark Ky |
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Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma.
The Journal of pathology 2017 08 242 (4): 500-510. Dai Wei, Ko Josephine Mun Yee, Choi Sheyne Sta Ana, Yu Zhouyou, Ning Luwen, Zheng Hong, Gopalan Vinod, Chan Kin Tak, Lee Nikki Pui-Yue, Chan Kwok Wah, Law Simon Ying-Kit, Lam Alfred King-Yin, Lung Maria |
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EGFR Gene Amplification and KRAS Mutation Predict Response to Combination Targeted Therapy in Metastatic Colorectal Cancer.
Pathology oncology research : POR 2016 Dec . Khan Sajid A, Zeng Zhaoshi, Shia Jinru, Paty Philip |
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Inactivating Mutations of RB1 and TP53 Correlate With Sarcomatous Histomorphology and Metastasis/Recurrence in Gastrointestinal Stromal Tumors.
American journal of clinical pathology 2016 Dec . Merten Larissa, Agaimy Abbas, Moskalev Evgeny A, Giedl Johannes, Kayser Claudia, Geddert Helene, Schaefer Inga-Marie, Cameron Silke, Werner Martin, Ströbel Philip, Hartmann Arndt, Haller Flori |
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The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies.
Oncotarget 2016 Nov . Tian Xin, Dai Shundong, Sun Jing, Jiang Shenyi, Jiang Youho |
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Mutation location on the RAS oncogene effects pathologic features and survival after resection of colorectal liver metastases.
Cancer 2016 Oct . Frankel Timothy L, Vakiani Efsevia, Nathan Hari, DeMatteo Ronald P, Kingham T Peter, Allen Peter J, Jarnagin William R, Kemeny Nancy E, Solit David B, D'Angelica Michael |
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Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Molecular cancer 2016 Oct 15 (1): 63. Kovaleva Valentina, Geissler Anna-Lena, Lutz Lisa, Fritsch Ralph, Makowiec Frank, Wiesemann Sebastian, Hopt Ulrich T, Passlick Bernward, Werner Martin, Lassmann Sil |
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Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
Gastroenterology 2016 Oct . Broderick Peter, Dobbins Sara E, Chubb Daniel, Kinnersley Ben, Dunlop Malcolm G, Tomlinson Ian, Houlston Richard |
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Integrated Genetic, Epigenetic and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumours.
Molecular cancer research : MCR 2016 Sep . Hesson Luke B, Ng Benedict, Zarzour Peter, Srivastava Sameer, Kwok Chau-To, Packham Deborah, Nunez Andrea C, Beck Dominik, Ryan Regina, Dower Ashraf, Ford Caroline E, Pimanda John, Sloane Mathew A, Hawkins Nicholas J, Bourke Michael J, Wong Jason W H, Ward Robyn |
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Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence.
Oncotarget 2016 Sep 7 (38): 62280-62291. Ueda Masami, Iguchi Tomohiro, Masuda Takaaki, Nakahara Yujiro, Hirata Hidenari, Uchi Ryutaro, Niida Atsushi, Momose Kota, Sakimura Shotaro, Chiba Kenichi, Eguchi Hidetoshi, Ito Shuhei, Sugimachi Keishi, Yamasaki Makoto, Suzuki Yutaka, Miyano Satoru, Doki Yuichiro, Mori Masaki, Mimori Kos |
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Study of apoptosis-related interactions in colorectal cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep . Arora Himanshu, Qureshi Rehana, Rizvi M A, Shrivastava Sharad, Parihar Mordhwaj |
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Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Gut 2016 Sep . Sievers Chelsie K, Zou Luli S, Pickhardt Perry J, Matkowskyj Kristina A, Albrecht Dawn M, Clipson Linda, Bacher Jeffery W, Pooler B Dustin, Moawad Fouad J, Cash Brooks D, Reichelderfer Mark, Vo Tien N, Newton Michael A, Larget Bret R, Halberg Richard |
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Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
World journal of gastroenterology 2016 Aug 22 (30): 6944-54. Lo Nigro Cristiana, Ricci Vincenzo, Vivenza Daniela, Granetto Cristina, Fabozzi Teresa, Miraglio Emanuela, Merlano Marco |
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Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.
Oncotarget 2016 Aug . Takane Kiyoko, Matsusaka Keisuke, Ota Satoshi, Fukuyo Masaki, Yue Yao, Nishimura Motoi, Sakai Eiji, Matsushita Kazuyuki, Miyauchi Hideaki, Aburatani Hiroyuki, Nakatani Yukio, Takayama Tadatoshi, Matsubara Hisahiro, Akagi Kiwamu, Kaneda Atsus |
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