HuGE Literature Finder
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Records 1-100
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Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2019 Jun . Zusi Chiara, Mantovani Alessandro, Olivieri Francesca, Morandi Anita, Corradi Massimiliano, Miraglia Del Giudice Emanuele, Dauriz Marco, Valenti Luca, Byrne Christopher D, Targher Giovanni, Maffeis Claud |
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Genetic polymorphisms associated with obesity and non-alcoholic fatty liver disease in Asian Indian adolescents.
Journal of pediatric endocrinology & metabolism : JPEM 2019 Jun . Jain Vandana, Kumar Anil, Ahmad Nayeem, Jana Manisha, Kalaivani Mani, Kumar Brijesh, Shastri Shivaram, Jain Oshima, Kabra Madhuli |
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Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
Obesity (Silver Spring, Md.) 2019 Jun . Young Kendra A, Palmer Nicholette D, Fingerlin Tasha E, Langefeld Carl D, Norris Jill M, Wang Nan, Xiang Anny H, Guo Xiuqing, Williams Adrienne H, Chen Yii-Der I, Taylor Kent D, Rotter Jerome I, Raffel Leslie J, Goodarzi Mark O, Watanabe Richard M, Wagenknecht Lynne |
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High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase-Lowering effect of a HSD17B13 Variant.
Hepatology (Baltimore, Md.) 2019 Jun . Gellert-Kristensen Helene, Nordestgaard Børge Grønne, Tybjaerg-Hansen Anne, Stender Stef |
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Nonalcoholic fatty liver disease and eGFR levels could be linked by the PNPLA3 I148M polymorphism in children with obesity.
Pediatric obesity 2019 Jun e12539. Marzuillo Pierluigi, Di Sessa Anna, Guarino Stefano, Capalbo Daniela, Umano Giuseppina Rosaria, Pedullà Marcella, La Manna Angela, Cirillo Grazia, Miraglia Del Giudice Emanue |
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The PNPLA3 rs738409 C>G variant influences the association between low skeletal muscle mass and NAFLD: the Shanghai Changfeng Study.
Alimentary pharmacology & therapeutics 2019 Jun . Xia Ming-Feng, Chen Ling-Yan, Wu Li, Ma Hui, Li Qian, Aleteng Qiqige, Hu Yu, He Wan-Yuan, Gao Jian, Lin Huan-Dong, Gao X |
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Interaction of TM6SF2 E167K and PNPLA3 I148M variants in NAFLD in northeast China.
Annals of hepatology 2019 Apr . Xu Min, Li Yiling, Zhang Shuang, Wang Xinyi, Shen Jianhua, Zhang Shuw |
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Validation of PNPLA3 polymorphisms as risk factor for NAFLD and liver fibrosis in an admixed population.
Annals of hepatology 2019 Apr . Mazo Daniel F, Malta Fernanda M, Stefano Jose Tadeu, Salles Ana Paula M, Gomes-Gouvea Michele S, Nastri Ana Catharina S, Almeida Jazon R, Pinho Joao Renato R, Carrilho Flair J, Oliveira Claudia |
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International journal of molecular sciences 2019 Mar 20 (6): . Basyte-Bacevice Viktorija, Skieceviciene Jurgita, Valantiene Irena, Sumskiene Jolanta, Petrenkiene Vitalija, Kondrackiene Jurate, Petrauskas Dalius, Lammert Frank, Kupcinskas Juoz |
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Collagen formation assessed by PRO-C3 is an heritable trait and is associated with liver fibrosis assessed by MRE.
Hepatology (Baltimore, Md.) 2019 Mar . Caussy Cyrielle, Bhargava Meera, Villesen Ida F, Gudmann Natasja S, Leeming Diana J, Karsdal Morten A, Faulkner Claire, Bao Denny, Liu Amy, Lo Min-Tzu, Bettencourt Ricki, Bassirian Shirin, Richards Lisa, Brenner David A, Chen Chi-Hua, Sirlin Claude B, Loomba Roh |
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Relationship between PNPLA3 rs738409 polymorphism and decreased kidney function in children with NAFLD.
Hepatology (Baltimore, Md.) 2019 Mar . Targher Giovanni, Mantovani Alessandro, Alisi Anna, Mosca Antonella, Panera Nadia, Byrne Christopher D, Nobili Valer |
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Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease (NAFLD) susceptibility and severity: A meta-analysis.
Medicine 2019 Feb 98 (7): e14324. Dai Guangrong, Liu Pengfei, Li Xiaomei, Zhou Xiaoyan, He Shuixia |
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Association between PNPLA3rs738409, polymorphism, decreased kidney function in postmenopausal type 2, diabetic women with or without non-alcoholic fatty liver disease.
Diabetes & metabolism 2019 Feb . Mantovani A, Zusi C, Sani E, Colecchia A, Lippi G, Zaza Gianluigi, Valenti L, Byrne C D, Maffeis C, Bonora E, Targher |
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Combining I148M and E167K variants to improve risk prediction for nonalcoholic fatty liver disease in Qingdao Han population, China.
Lipids in health and disease 2019 Feb 18 (1): 45. Chen Li-Zhen, Ding Hong-Yun, Liu Shou-Sheng, Liu Qun, Jiang Xiang-Jun, Xin Yong-Ning, Xuan Shi-Yi |
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The PNPLA3 rs738409 C>G variant interacts with changes in body weight over time to aggravate liver steatosis, but reduces the risk of incident type 2 diabetes.
Diabetologia 2019 Jan . Xia Ming-Feng, Lin Huan-Dong, Chen Ling-Yan, Wu Li, Ma Hui, Li Qian, Aleteng Qiqige, Hu Yu, He Wan-Yuan, Gao Jian, Bian Hua, Li Xiao-Ying, Gao X |
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No effect of MTP polymorphisms on PNPLA3 in HCV-correlated steatosis.
Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2018 Sep 26 (3): 244-248. Zampino Rosa, Macera Margherita, Cirillo Grazia, Pafundi Clara, Rinaldi Luca, Coppola Nicola, Pisaturo Mariantonietta, Adinolfi Luigi Elio, Miraglia Del Giudice Emanuele, Ingrosso Diego, Capasso Rosan |
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Patatin-like phospholipase domain containing 3 variants differentially impact metabolic traits in individuals at high risk for cardiovascular events.
Hepatology communications 2018 Jul 2 (7): 798-806. Rüschenbaum Sabrina, Schwarzkopf Katharina, Friedrich-Rust Mireen, Seeger Florian, Schoelzel Fabian, Martinez Yolanda, Zeuzem Stefan, Bojunga Jörg, Lange Christian |
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Impact of patatin-like phospholipase domain containing 3 rs738409 G/G genotype on hepatic decompensation and mortality in patients with portal hypertension.
Alimentary pharmacology & therapeutics 2018 Jun . Mandorfer M, Scheiner B, Stättermayer A F, Schwabl P, Paternostro R, Bauer D, Schäfer B, Zoller H, Peck-Radosavljevic M, Trauner M, Reiberger T, Ferenci P, Ferlitsch |
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Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors.
Nutrients 2018 May 10 (5): . Tiwari-Heckler Shilpa, Gan-Schreier Hongying, Stremmel Wolfgang, Chamulitrat Walee, Pathil Ani |
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Donor PNPLA3 rs738409 genotype is a risk factor for graft steatosis. A post-transplant biopsy-based study.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2018 May 50 (5): 490-495. Trunecka Pavel, Míková Irena, Dlouhá Dana, Hubácek Jaroslav A, Honsová Eva, Kolesár Libor, Lánská Vera, Franková Sona, Šperl Jan, Jirsa Milan, Poledne Rudo |
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High frequency of the PNPLA3 rs738409 [G] single-nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease.
Cancer 2018 Apr 124 Suppl 7 1583-1589. Tepper Clifford G, Dang Julie H T, Stewart Susan L, Fang Dao M, Wong Kimberly A, Liu Stephenie Y, Davis Ryan R, Dao Doan Y, Gregg Jeffrey P, Török Natalie J, Chen Moon |
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Metabolic Features of Nonalcoholic Fatty Liver (NAFL) in Obese Adolescents: Findings from a Multi-ethnic Cohort.
Hepatology (Baltimore, Md.) 2018 Apr . Tricò Domenico, Caprio Sonia, Umano Giuseppina Rosaria, Pierpont Bridget, Nouws Jessica, Galderisi Alfonso, Kim Grace, Mata Mariana M, Santoro Nico |
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The relationship between obesity and the severity of non-alcoholic fatty liver disease: systematic review and meta-analysis.
Expert review of gastroenterology & hepatology 2018 Apr 1-12. Lu Feng-Bin, Hu En-De, Xu Lan-Man, Chen Lu, Wu Jin-Lu, Li Hui, Chen Da-Zhi, Chen Yong-Pi |
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The rs4686434 variant in the FETUB locus is associated with intrahepatic triglyceride content in obese Chinese adults.
Journal of diabetes 2018 Apr . Li Zhibin, Lin Mingzhu, Liu Changqin, Chen Zheng, Wang Dongmei, Shi Xiulin, Yang Shuyu, Li Xuej |
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Fish intake interacts with TM6SF2 gene variant to affect NAFLD risk: results of a case-control study.
European journal of nutrition 2018 Mar . Kalafati I P, Dimitriou M, Borsa D, Vlachogiannakos J, Revenas K, Kokkinos A, Ladas S D, Dedoussis G |
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More Evidence for the Genetic Susceptibility of Mexican Population to Nonalcoholic Fatty Liver Disease through PNPLA3.
Annals of hepatology 2018 Mar 17 (2): 250-255. Chinchilla-López Paulina, Ramírez-Pérez Oscar, Cruz-Ramón Vania, Canizales-Quinteros Samuel, Domínguez-López Aarón, Ponciano-Rodríguez Guadalupe, Sánchez-Muñoz Fausto, Méndez-Sánchez Nah |
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The Membrane-bound O-Acyltransferase7 rs641738 Variant in Pediatric Nonalcoholic Fatty Liver Disease.
Journal of pediatric gastroenterology and nutrition 2018 Mar . Di Sessa Anna, Umano Giuseppina Rosaria, Cirillo Grazia, Del Prete Angela, Iacomino Roberta, Marzuillo Pierluigi, Giudice Emanuele Miraglia D |
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Could inherited predisposition drive non-obese fatty liver disease? Results from German tertiary referral centers.
Journal of human genetics 2018 Feb . Krawczyk Marcin, Bantel Heike, Rau Monika, Schattenberg Jörn M, Grünhage Frank, Pathil Anita, Demir Münevver, Kluwe Johannes, Boettler Tobias, Weber Susanne N, Geier Andreas, Lammert Frank, |
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The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth.
The American journal of gastroenterology 2018 Feb . Umano Giuseppina R, Caprio Sonia, Di Sessa Anna, Chalasani Naga, Dykas Daniel J, Pierpont Bridget, Bale Allen E, Santoro Nico |
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Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.
Experimental and molecular pathology 2018 Jan 104 (1): 50-58. Larrieta-Carrasco Elena, Flores Yvonne N, Macías-Kauffer Luis R, Ramírez-Palacios Paula, Quiterio Manuel, Ramírez-Salazar Eric G, León-Mimila Paola, Rivera-Paredez Berenice, Cabrera-Álvarez Guillermo, Canizales-Quinteros Samuel, Zhang Zuo-Feng, López-Pérez Tania V, Salmerón Jorge, Velázquez-Cruz Rafa |
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A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.
The New England journal of medicine 2018 03 378 (12): 1096-1106. Abul-Husn Noura S, Cheng Xiping, Li Alexander H, Xin Yurong, Schurmann Claudia, Stevis Panayiotis, Liu Yashu, Kozlitina Julia, Stender Stefan, Wood G Craig, Stepanchick Ann N, Still Matthew D, McCarthy Shane, O'Dushlaine Colm, Packer Jonathan S, Balasubramanian Suganthi, Gosalia Nehal, Esopi David, Kim Sun Y, Mukherjee Semanti, Lopez Alexander E, Fuller Erin D, Penn John, Chu Xin, Luo Jonathan Z, Mirshahi Uyenlinh L, Carey David J, Still Christopher D, Feldman Michael D, Small Aeron, Damrauer Scott M, Rader Daniel J, Zambrowicz Brian, Olson William, Murphy Andrew J, Borecki Ingrid B, Shuldiner Alan R, Reid Jeffrey G, Overton John D, Yancopoulos George D, Hobbs Helen H, Cohen Jonathan C, Gottesman Omri, Teslovich Tanya M, Baras Aris, Mirshahi Tooraj, Gromada Jesper, Dewey Frederick |
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PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC.
PloS one 2018 13 (8): e0202942. Kruk Beata, Liebe Roman, Milkiewicz Ma?gorzata, Wunsch Ewa, Raszeja-Wyszomirska Joanna, Lammert Frank, Milkiewicz Piotr, Krawczyk Marc |
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Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.
PloS one 2018 13 (1): e0185490. Kawaguchi Takahisa, Shima Toshihide, Mizuno Masayuki, Mitsumoto Yasuhide, Umemura Atsushi, Kanbara Yoshihiro, Tanaka Saiyu, Sumida Yoshio, Yasui Kohichiro, Takahashi Meiko, Matsuo Keitaro, Itoh Yoshito, Tokushige Katsutoshi, Hashimoto Etsuko, Kiyosawa Kendo, Kawaguchi Masanori, Itoh Hiroyuki, Uto Hirofumi, Komorizono Yasuji, Shirabe Ken, Takami Shiro, Takamura Toshinari, Kawanaka Miwa, Yamada Ryo, Matsuda Fumihiko, Okanoue Takes |
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Association of PNPLA3 rs738409 polymorphism with Liver Steatosis but not with Cirrhosis in Patients with HBV Infection: Systematic Review with Meta-analysis.
The journal of gene medicine 2017 Dec . Ghalamkari Saman, Sharafi Heidar, Alavian Seyed Moay |
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Genetic Polymorphisms of PNPLA3 and SAMM50 Are Associated with Nonalcoholic Fatty Liver Disease in a Korean Population.
Gut and liver 2017 Dec . Chung Goh Eun, Lee Young, Yim Jeong Yoon, Choe Eun Kyung, Kwak Min-Sun, Yang Jong In, Park Boram, Lee Jong-Eun, Kim Jeong A, Kim Joo Su |
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Additive effects of PNPLA3 and TM6SF2 on the histological severity of non-alcoholic fatty liver disease.
Journal of gastroenterology and hepatology 2017 Nov . Koo Bo Kyung, Joo Sae Kyung, Kim Donghee, Bae Jeong Mo, Park Jeong Hwan, Kim Jung Ho, Kim W |
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Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities.
World journal of hepatology 2017 Sep 9 (26): 1101-1107. Bale Govardhan, Steffie Avanthi Urmila, Ravi Kanth Vishnubhotla Venkata, Rao Padaki Nagaraja, Sharma Mithun, Sasikala Mitnala, Reddy Duvvur Nageshw |
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Combination of PNPLA3 and TLL1 polymorphism can predict advanced fibrosis in Japanese patients with nonalcoholic fatty liver disease.
Journal of gastroenterology 2017 Jul . Seko Yuya, Yamaguchi Kanji, Mizuno Naoki, Okuda Keiichiro, Takemura Masashi, Taketani Hiroyoshi, Hara Tasuku, Umemura Atsushi, Nishikawa Taichiro, Moriguchi Michihisa, Yasui Kohichiroh, Kamaguchi Mai, Nishioji Kenichi, Mochizuki Naomi, Kobayashi Masao, Mori Kojiroh, Tanaka Saiyu, Matsuura Kentaro, Tanaka Yasuhito, Itoh Yoshi |
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Effect of PNPLA3 I148M Polymorphism on Histologically Proven Nonalcoholic Fatty Liver Disease in Liver Transplant Recipients.
Hepatology research : the official journal of the Japan Society of Hepatology 2017 Jul . Kim Hyeyoung, Lee Kwang-Woong, Lee Kyoungbun, Seo Sooin, Park Min-Young, Ahn Sung Woo, Hong Suk Kyun, Yoon Kyung Chul, Kim Hyo-Sin, Choi YoungRok, Lee Hae Won, Yi Nam-Joon, Suh Kyung-S |
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Liver and Cardiovascular Damage in Patients With Lean Non-alcoholic Fatty Liver Disease, and Association With Visceral Obesity.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2017 May . Fracanzani Anna Ludovica, Petta Salvatore, Lombardi Rosa, Pisano Giuseppina, Russello Maurizio, Consonni Dario, Di Marco Vito, Cammà Calogero, Mensi Laura, Dongiovanni Paola, Valenti Luca, Craxì Antonio, Fargion Silv |
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Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease.
The American journal of gastroenterology 2017 May . Bugianesi Elisabetta, Bizzarri Carla, Rosso Chiara, Mosca Antonella, Panera Nadia, Veraldi Silvio, Dotta Andrea, Giannone Germana, Raponi Massimiliano, Cappa Marco, Alisi Anna, Nobili Valer |
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Polymorphism of Receptor-Type Tyrosine-Protein Phosphatase Delta gene in the development of non-alcoholic fatty liver disease.
Journal of gastroenterology and hepatology 2017 May . Nakajima Shunsuke, Tanaka Hiroki, Sawada Koji, Hayashi Hidemi, Hasebe Takumu, Abe Masami, Hasebe Chitomi, Fujiya Mikihiro, Okumura Toshikat |
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The association of nonalcoholic fatty liver disease with genetic polymorphisms: a multicenter study.
European journal of gastroenterology & hepatology 2017 Apr 29 (4): 441-447. Uygun Ahmet, Ozturk Kadir, Demirci Hakan, Oztuna Ali, Eren Fatih, Kozan Salih, Yilmaz Yusuf, Kurt Omer, Turker Turker, Vatansever Sezgin, Alper Emrah, Unsal Belk |
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Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease.
Journal of clinical gastroenterology 2017 Mar . Jiang Zhenghui G, Tapper Elliot B, Kim Misung, Connelly Margery A, Krawczyk Sarah A, Yee Eric U, Herman Mark A, Mukamal Kenneth J, Lai Michel |
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Hepatic nucleotide binding oligomerization domain-like receptors pyrin domain-containing 3 inflammasomes are associated with the histologic severity of nonalcoholic fatty liver disease.
Hepatology research : the official journal of the Japan Society of Hepatology 2017 Feb . Mitsuyoshi Hironori, Yasui Kohichiroh, Hara Tasuku, Taketani Hiroyoshi, Ishiba Hiroshi, Okajima Akira, Seko Yuya, Umemura Atsushi, Nishikawa Taichiro, Yamaguchi Kanji, Moriguchi Michihisa, Minami Masahito, Itoh Yoshi |
Genome-wide study links PNPLA3 variant with elevated hepatic transaminase after acute lymphoblastic leukemia therapy.
Clinical pharmacology and therapeutics 2017 Jan . Liu Yiwei, Fernandez Christian A, Smith Colton, Yang Wenjian, Cheng Cheng, Panetta John C, Kornegay Nancy, Liu Chengcheng, Ramsey Laura B, Karol Seth E, Janke Laura J, Larsen Eric C, Winick Naomi, Carroll William L, Loh Mignon L, Raetz Elizabeth A, Hunger Stephen P, Devidas Meenakshi, Yang Jun J, Mullighan Charles G, Zhang Jinghui, Evans William E, Jeha Sima, Pui Ching-Hon, Relling Mary |
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The MBOAT7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B.
Hepatology (Baltimore, Md.) 2017 Jan . Thabet Khaled, Chan Henry Lik Yuen, Petta Salvatore, Mangia Alessandra, Berg Thomas, Boonstra Andre, Brouwer Willem P, Abate Maria Lorena, Wong Vincent Wai-Sun, Nazmy Maiiada, Fischer Janett, Liddle Christopher, George Jacob, Eslam Mohamm |
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The Expression of PNPLA3 Polymorphism could be the Key for Severe Liver Disease in NAFLD in Hispanic Population.
Annals of hepatology 2017 10 16 (6): 909-915. Martínez Leonardo A, Larrieta Elena, Kershenobich David, Torre Al |
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Physical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.
BMC medical genetics 2016 Dec 17 (1): 90. Wang Shuo, Song Jieyun, Shang Xiaorui, Chawla Nitesh, Yang Yide, Meng Xiangrui, Wang Haijun, Ma J |
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PNPLA3 p.I148M variant is associated with greater reduction of liver fat content after bariatric surgery.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2016 Dec 12 (10): 1838-1846. Krawczyk Marcin, Jiménez-Agüero Raúl, Alustiza José M, Emparanza José I, Perugorria María J, Bujanda Luis, Lammert Frank, Banales Jesús |
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PNPLA3 polymorphism increases risk for and severity of chronic hepatitis C liver disease.
World journal of hepatology 2016 Dec 8 (35): 1584-1592. Salameh Habeeb, Masadeh Maen, Al Hanayneh Muhannad, Petros Vincent, Maslonka Matthew, Nanda Arjun, Singal Ashwani |
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Combined effects of the TM6SF2 rs58542926, PNPLA3 rs738409 and MBOAT7 rs641738 variants on NAFLD severity: multicentre biopsy-based study.
Journal of lipid research 2016 Nov . Krawczyk Marcin, Rau Monika, Schattenberg Jörn M, Bantel Heike, Pathil Anita, Demir Münevver, Kluwe Johannes, Boettler Tobias, Lammert Frank, Geier Andre |
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Development of hepatocellular carcinoma in Japanese patients with biopsy-proven non-alcoholic fatty liver disease: Association between PNPLA3 genotype and hepatocarcinogenesis/fibrosis progression.
Hepatology research : the official journal of the Japan Society of Hepatology 2016 Nov . Seko Yuya, Sumida Yoshio, Tanaka Saiyu, Mori Kojiroh, Taketani Hiroyoshi, Ishiba Hiroshi, Hara Tasuku, Okajima Akira, Umemura Atsushi, Nishikawa Taichiro, Yamaguchi Kanji, Moriguchi Michihisa, Kanemasa Kazuyuki, Yasui Kohichiroh, Imai Shunsuke, Shimada Keiji, Itoh Yoshi |
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Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study.
Immunobiology 2016 Sep . Posadas-Sánchez Rosalinda, López-Uribe Ángel René, Posadas-Romero Carlos, Pérez-Hernández Nonanzit, Rodríguez-Pérez José Manuel, Ocampo-Arcos Wendy Angélica, Fragoso José Manuel, Cardoso-Saldaña Guillermo, Vargas-Alarcón Gilber |
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The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH).
BMC medical genetics 2016 Sep 17 (1): 63. Mehta Rohini, Jeiran Kianoush, Koenig Aaron B, Otgonsuren Munkzhul, Goodman Zachary, Baranova Ancha, Younossi Zoba |
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APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.
Digestive diseases and sciences 2016 Aug 61 (8): 2284-93. Zhang Rui-Nan, Zheng Rui-Dan, Mi Yu-Qiang, Zhou Da, Shen Feng, Chen Guang-Yu, Zhu Chan-Yan, Pan Qin, Fan Jian-G |
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Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.
Journal of gastroenterology and hepatology 2016 Aug . Chan Anthony W H, Wong Grace L H, Chan Hoi-Yun, Tong Joanna H M, Yu Yau-Hei, Choi Paul C L, Chan Henry L Y, To Ka-Fai, Wong Vincent W |
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Association of MBOAT7 gene variant with plasma ALT levels in children: the PANIC study.
Pediatric research 2016 Jul . Anna Viitasalo, Aino-Maija Eloranta, Mustafa Atalay, Stefano Romeo, Jussi Pihlajamäki, Timo A Lak |
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Steatotic hepatocellular carcinoma: A variant associated with metabolic factors and late tumor relapse.
Histopathology 2016 Jul . Chan Anthony W H, Yu Shuangni, Yu Yau-Hei, Tong Joanna H M, Wang Lei, Tin Edith K Y, Chong Charing C N, Chan Stephen L, Wong Grace L H, Wong Vincent W S, Chan Henry L Y, Lai Paul B S, To Ka-F |
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Variants in the Autophagy Related Gene IRGM Confer Susceptibility to Nonalcoholic Fatty Liver Disease by Modulating Lipophagy.
Journal of hepatology 2016 Jul . Lin Yu-Cheng, Chang Pi-Feng, Lin Hsueh-Fang, Liu Kevin, Chang Mei-Hwei, Ni Yen-Hsu |
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Screening for rare variants in the PNPLA3 gene in obese liver biopsy patients.
Clinics and research in hepatology and gastroenterology 2016 Jun . Zegers Doreen, Verrijken An, Francque Sven, de Freitas Fenna, Beckers Sigri, Aerts Evi, Ruppert Martin, Hubens Guy, Michielsen Peter, Van Hul Wim, Van Gaal Luc |
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[Influence of leptin receptor gene K109R polymorphism on the risk of nonalcoholic fatty liver disease and its interaction with PNPLA3 I148M polymorphism].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2016 May 24 (5): 358-62. An B Q, Jiang M, Cheng Y T, Yuan C, Lu L L, Xin Y N, Xuan S |
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Childhood Predictors of Adult Fatty Liver. The Cardiovascular Risk in Young Finns Study.
Journal of hepatology 2016 May . Suomela Emmi, Oikonen Mervi, Pitkänen Niina, Ahola-Olli Ari, Virtanen Johanna, Parkkola Riitta, Jokinen Eero, Laitinen Tomi, Hutri-Kähönen Nina, Kähönen Mika, Lehtimäki Terho, Taittonen Leena, Tossavainen Päivi, Jula Antti, Loo Britt-Marie, Mikkilä Vera, Telama Risto, Viikari Jorma S A, Juonala Markus, Raitakari Olli |
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Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients.
Medicine 2016 Mar 95 (12): e3120. Tai Chi-Ming, Huang Chih-Kun, Tu Hung-Pin, Hwang Jau-Chung, Yeh Ming-Lun, Huang Chung-Feng, Huang Jee-Fu, Dai Chia-Yen, Chuang Wan-Long, Yu Ming-Lu |
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I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders.
Alimentary pharmacology & therapeutics 2016 Jan . Xia M-F, Ling Y, Bian H, Lin H-D, Yan H-M, Chang X-X, Li X-M, Ma H, Wang D, Zhang L-S, Wang S-S, Wu B-J, He W-Y, Zhao N-Q, Gao |
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The characteristics of non-obese NAFLD: Effect of genetic and environmental factors.
Hepatology research : the official journal of the Japan Society of Hepatology 2016 Jan . Honda Yasushi, Yoneda Masato, Kessoku Takaomi, Ogawa Yuji, Tomeno Wataru, Imajo Kento, Mawatari Hironori, Fujita Koji, Hyogo Hideyuki, Ueno Takato, Chayama Kazuaki, Saito Satoru, Nakajima Atsushi, Hotta Kiku |
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Epicardial Adipose Tissue (EAT) Thickness Is Associated with Cardiovascular and Liver Damage in Nonalcoholic Fatty Liver Disease.
PloS one 2016 11 (9): e0162473. Fracanzani Anna Ludovica, Pisano Giuseppina, Consonni Dario, Tiraboschi Silvia, Baragetti Andrea, Bertelli Cristina, Norata Giuseppe Danilo, Dongiovanni Paola, Valenti Luca, Grigore Liliana, Tonella Tatiana, Catapano Alberico, Fargion Silv |
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Meta-analysis of the influence of TM6SF2 E167K variant on Plasma Concentration of Aminotransferases across different Populations and Diverse Liver Phenotypes.
Scientific reports 2016 6 27718. Sookoian Silvia, Pirola Carlos |
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The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients.
PloS one 2016 11 (12): e0168265. Núñez-Torres Rocío, Macías Juan, Mancebo María, Frías Mario, Dolci Giovanni, Téllez Francisco, Merino Dolores, Merchante Nicolás, Gómez-Mateos Jesús, Guaraldi Giovanni, Rivero-Juárez Antonio, Pineda Juan A, Real Luis M, |
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Genetic analysis of nonalcoholic fatty liver disease within a Caribbean-Hispanic population.
Molecular genetics & genomic medicine 2015 Nov 3 (6): 558-69. Edelman Deborah, Kalia Harmit, Delio Maria, Alani Mustafa, Krishnamurthy Karthik, Abd Mortadha, Auton Adam, Wang Tao, Wolkoff Allan W, Morrow Bernice |
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The rs2294918 E434K variant modulates PNPLA3 expression and liver damage.
Hepatology (Baltimore, Md.) 2015 Nov . Donati Benedetta, Motta Benedetta Maria, Pingitore Piero, Meroni Marica, Pietrelli Alessandro, Alisi Anna, Petta Salvatore, Xing Chao, Dongiovanni Paola, Del Menico Benedetta, Rametta Raffaela, Mancina Rosellina Margherita, Badiali Sara, Fracanzani Anna Ludovica, Craxì Antonio, Fargion Silvia, Nobili Valerio, Romeo Stefano, Valenti Lu |
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Association study of PNPLA2 gene with histological parameters of NAFLD in an obese population.
Clinics and research in hepatology and gastroenterology 2015 Oct . Zegers Doreen, Verrijken An, Beckers Sigri, Francque Sven, Van Camp Jasmijn K, Aerts Evi, Ruppert Martin, Hubens Guy, Michielsen Peter, Van Hul Wim, Van Gaal Luc |
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Role of the TM6SF2 rs58542926 in the pathogenesis of non-alcoholic pediatric fatty liver disease (NAFLD): A multiethnic study.
Hepatology (Baltimore, Md.) 2015 Oct . Goffredo Martina, Caprio Sonia, Feldstein Ariel E, D'Adamo Ebe, Shaw Melissa M, Pierpont Bridget, Savoye Mary, Zhao Hongyu, Bale Allen E, Santoro Nico |
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The genetic variant I148M in PNPLA3 is associated with increased hepatic retinyl-palmitate storage in humans.
The Journal of clinical endocrinology and metabolism 2015 Oct jc20152978. Kovarova Marketa, Königsrainer Ingmar, Königsrainer Alfred, Machicao Fausto, Häring Hans-Ulrich, Schleicher Erwin, Peter Andre |
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PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.
Inflammatory bowel diseases 2015 Sep . Mancina Rosellina Margherita, Spagnuolo Rocco, Milano Marta, Brogneri Simona, Morrone Attilio, Cosco Cristina, Lazzaro Veronica, Russo Cristina, Ferro Yvelise, Pingitore Piero, Pujia Arturo, Montalcini Tiziana, Doldo Patrizia, Garieri Pietro, Piodi Luca, Caprioli Flavio, Valenti Luca, Romeo Stefa |
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PNPLA3 I148M variant affects non-alcoholic fatty liver disease in liver transplant recipients.
World journal of gastroenterology : WJG 2015 Sep 21 (34): 10054-6. Liu Zheng-Tao, Chen Tian-Chi, Lu Xiao-Xiao, Cheng Jun, Xie Hai-Yang, Zhou Lin, Zheng Shu-S |
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PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2015 Sep . Falleti Edmondo, Cussigh Annarosa, Cmet Sara, Fabris Carlo, Toniutto Pierlui |
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Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.
Journal of gastroenterology 2015 Aug 50 (8): 887-93. Yasui Kohichiroh, Kawaguchi Takahisa, Shima Toshihide, Mitsuyoshi Hironori, Seki Kojiro, Sendo Rei, Mizuno Masayuki, Itoh Yoshito, Matsuda Fumihiko, Okanoue Takes |
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The common PNPLA3 variant p.I148M is associated with liver fat contents as quantified by controlled attenuation parameter (CAP).
Liver international : official journal of the International Association for the Study of the Liver 2015 Aug . Arslanow Anita, Stokes Caroline S, Weber Susanne N, Grünhage Frank, Lammert Frank, Krawczyk Marc |
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Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: results from the WELCOME trial.
Journal of hepatology 2015 Aug . Scorletti Eleonora, West Annette L, Bhatia Lokpal, Hoile Samuel P, McCormick Keith G, Burdge Graham C, Lillycrop Karen A, Clough Geraldine F, Calder Philip C, Byrne Christopher |
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Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations.
Journal of hepatology 2015 Jul 63 (1): 156-63. Stättermayer Albert Friedrich, Traussnigg Stefan, Dienes Hans-Peter, Aigner Elmar, Stauber Rudolf, Lackner Karoline, Hofer Harald, Stift Judith, Wrba Friedrich, Stadlmayr Andreas, Datz Christian, Strasser Michael, Maieron Andreas, Trauner Michael, Ferenci Pet |
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Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.
Hepatology research : the official journal of the Japan Society of Hepatology 2015 Jul . Kan Hiromi, Hyogo Hideyuki, Ochi Hidenori, Hotta Kikuko, Fukuhara Takayuki, Kobayashi Tomoki, Naeshiro Noriaki, Honda Yohji, Kawaoka Tomokazu, Tsuge Masataka, Hiramatsu Akira, Imamura Michio, Kawakami Yoshiiku, Aikata Hiroshi, Chayama Kazua |
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Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B.
World journal of gastroenterology : WJG 2015 Jul 21 (28): 8605-14. Pan Qin, Zhang Rui-Nan, Wang Yu-Qin, Zheng Rui-Dan, Mi Yu-Qiang, Liu Wen-Bin, Shen Feng, Chen Guang-Yu, Lu Jia-Fa, Zhu Chan-Yan, Zhang Shu-Yi, Chen Yi-Ming, Sun Wan-Lu, Fan Jian-G |
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Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages.
Alimentary pharmacology & therapeutics 2015 Jul 42 (1): 99-105. Mangge H, Baumgartner B G, Zelzer S, Prüller F, Schnedl W J, Reininghaus E Z, Haybaeck J, Lackner C, Stauber R, Aigner E, Weghuber |
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TM6SF2 rs58542926 is not associated with steatosis and fibrosis in large cohort of patients with genotype 1 chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver 2015 Jul . Petta Salvatore, Maida Marcello, Grimaudo Stefania, Pipitone Rosaria M, Macaluso Fabio S, Cabibi Daniela, Cammà Calogero, Di Marco Vito, Sferrazza Sandro, Craxì Anton |
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Impact of IL28B and PNPLA3 polymorphisms on treatment outcomes in patients infected with genotype 6 hepatitis C virus.
Journal of gastroenterology and hepatology 2015 Jun 30 (6): 1040-8. Wong Grace Lai-Hung, Chan Henry Lik-Yuen, Tse Chi-Hang, Chan Polly Oi-Ying, Cheng Joe Cho-Yiu, Cheng Jackie Siu-Woon, Lau Sharon Hoi-Ying, Lee Elbert Kam-Yeung, Ma Justin Ming-Yin, Chan Anthony Wing-Hung, Choi Paul Cheung-Lung, Wong Vincent Wai-S |
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PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.
The American journal of gastroenterology 2015 Jun 110 (6): 846-56. Salameh Habeeb, Raff Evan, Erwin Angelika, Seth Devanshi, Nischalke Hans Dieter, Falleti Edmondo, Burza Maria Antonella, Leathert Julian, Romeo Stefano, Molinaro Antonio, Corradini Stefano Ginanni, Toniutto Pierluigi, Spengler Ulrich, Ulrich Spengler, Daly Ann, Day Christopher P, Kuo Yong-Fang, Singal Ashwani |
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GWAS-Identified Common Variants With Nonalcoholic Fatty Liver Disease in Chinese Children.
Journal of pediatric gastroenterology and nutrition 2015 May 60 (5): 669-74. Shang Xiao-Rui, Song Jie-Yun, Liu Fang-Hong, Ma Jun, Wang Hai-J |
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Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant.
The Journal of clinical endocrinology and metabolism 2015 May 100 (5): E821-5. Mancina Rosellina M, Matikainen Niina, Maglio Cristina, Söderlund Sanni, Lundbom Nina, Hakkarainen Antti, Rametta Raffaela, Mozzi Enrico, Fargion Silvia, Valenti Luca, Romeo Stefano, Taskinen Marja-Riitta, Borén J |
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PNPLA3 polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: a meta-analysis.
Journal of gastroenterology and hepatology 2015 May 30 (5): 821-9. Zhang Long, You Wei, Zhang Hanze, Peng Rui, Zhu Qin, Yao Aihua, Li Xiangcheng, Zhou Yebin, Wang Xuehao, Pu Liyong, Wu Jind |
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PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C.
Alimentary pharmacology & therapeutics 2015 May 41 (10): 939-48. Petta S, Vanni E, Bugianesi E, Rosso C, Cabibi D, Cammà C, Di Marco V, Eslam M, Grimaudo S, Macaluso F S, McLeod D, Pipitone R M, Abate M L, Smedile A, George J, Craxì |
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A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity.
Experimental and molecular pathology 2015 Apr 98 (2): 178-83. León-Mimila Paola, Vega-Badillo Joel, Gutiérrez-Vidal Roxana, Villamil-Ramírez Hugo, Villareal-Molina Teresa, Larrieta-Carrasco Elena, López-Contreras Blanca E, Kauffer Luis R Macías, Maldonado-Pintado Diana G, Méndez-Sánchez Nahúm, Tovar Armando R, Hernández-Pando Rogelio, Velázquez-Cruz Rafael, Campos-Pérez Francisco, Aguilar-Salinas Carlos A, Canizales-Quinteros Samu |
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Genome-wide analysis of hepatic lipid content in extreme obesity.
Acta diabetologica 2015 Apr 52 (2): 373-82. DiStefano Johanna K, Kingsley Christopher, Craig Wood G, Chu Xin, Argyropoulos George, Still Christopher D, Doné Stefania Cotta, Legendre Christophe, Tembe Waibhav, Gerhard Glenn |
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TM6SF2 Glu167Lys polymorphism is associated with low levels of LDL-cholesterol and increased liver injury in obese children.
Pediatric obesity 2015 Apr . Grandone A, Cozzolino D, Marzuillo P, Cirillo G, Di Sessa A, Ruggiero L, Di Palma M R, Perrone L, Miraglia Del Giudice |
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Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity.
Hepatology (Baltimore, Md.) 2015 Feb 61 (2): 515-25. Sookoian Silvia, Castaño Gustavo O, Scian Romina, Mallardi Pablo, Fernández Gianotti Tomas, Burgueño Adriana L, San Martino Julio, Pirola Carlos |
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Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes.
The American journal of clinical nutrition 2015 Feb 101 (2): 310-8. Bo Simona, Gambino Roberto, Menato Guido, Canil Stefania, Ponzo Valentina, Pinach Silvia, Durazzo Marilena, Ghigo Ezio, Cassader Maurizio, Musso Giovan |
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Noninvasive characterization of graft steatosis after liver transplantation.
Scandinavian journal of gastroenterology 2015 Feb 50 (2): 224-32. Karlas Thomas, Kollmeier Johanna, Böhm Stephan, Müller Jürgen, Kovacs Peter, Tröltzsch Michael, Weimann Antje, Bartels Michael, Rosendahl Jonas, Mössner Joachim, Berg Thomas, Keim Volker, Wiegand Johann |
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The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients.
Liver international : official journal of the International Association for the Study of the Liver 2015 Feb 35 (2): 438-47. Brouwer Willem P, van der Meer Adriaan J, Boonstra Andre, Pas Suzan D, de Knegt Robert J, de Man Rob A, Hansen Bettina E, ten Kate Fiebo J W, Janssen Harry L |
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Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease.
Hepatology (Baltimore, Md.) 2015 Feb 61 (2): 506-14. Dongiovanni Paola, Petta Salvatore, Maglio Cristina, Fracanzani Anna Ludovica, Pipitone Rosaria, Mozzi Enrico, Motta Benedetta Maria, Kaminska Dorota, Rametta Raffaela, Grimaudo Stefania, Pelusi Serena, Montalcini Tiziana, Alisi Anna, Maggioni Marco, Kärjä Vesa, Borén Jan, Käkelä Pirjo, Di Marco Vito, Xing Chao, Nobili Valerio, Dallapiccola Bruno, Craxi Antonio, Pihlajamäki Jussi, Fargion Silvia, Sjöström Lars, Carlsson Lena M, Romeo Stefano, Valenti Lu |
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PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease.
Journal of gastroenterology and hepatology 2015 Jan 30 (1): 139-46. Shen Jiayun, Wong Grace Lai-Hung, Chan Henry Lik-Yuen, Chan Ruth Suk-Mei, Chan Hoi-Yun, Chu Winnie Chiu-Wing, Cheung Bernice Ho-Ki, Yeung David Ka-Wai, Li Liz Sin, Sea Mandy Man-Mei, Woo Jean, Wong Vincent Wai-S |
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