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| Impact of CYP2C19 and CYP2C9 gene polymorphisms on sodium valproate plasma concentration in patients with epilepsy. European journal of hospital pharmacy : science and practice 2020 Aug . Song Cangsang, Li Xingde, Mao Panpan, Song Wenbing, Liu Lu, Zhang Ya |
| CYP2C9 (*2&*3) and CYP2C19 (*2&*3) polymorphisms among children with nonlesional epilepsy: a single-center study. Acta neurologica Belgica 2020 Jul . Eltalal Samah, El Ayouty Mostafa, El-Said Afaf, Wahba Yah |
| Effect of CYP2C19, UGT1A8, and UGT2B7 on valproic acid clearance in children with epilepsy: a population pharmacokinetic model. European journal of clinical pharmacology 2018 Aug 74 (8): 1029-1036. Mei Shenghui, Feng Weixing, Zhu Leting, Li Xingang, Yu Yazhen, Yang Weili, Gao Baoqin, Wu Xiaojuan, Fang Fang, Zhao Zhiga |
| Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region. Drugs in R&D 2017 Jul . Dagenais Renée, Wilby Kyle John, Elewa Hazem, Ensom Mary H |
| A prospective study to assess the association between genotype, phenotype and Prakriti in individuals on phenytoin monotherapy. Journal of Ayurveda and integrative medicine 2017 Mar . Thaker Saket J, Gandhe Prajakta P, Godbole Charuta J, Bendkhale Shital R, Mali Nitin B, Thatte Urmila M, Gogtay Nithya |
| Influence of genetic variants of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 on antiepileptic drug metabolism in pediatric patients with refractory epilepsy. Pharmacological reports : PR 2017 Jan 69 (3): 504-511. López-García Miguel A, Feria-Romero Iris A, Serrano Héctor, Rayo-Mares Darío, Fagiolino Pietro, Vázquez Marta, Escamilla-Núñez Consuelo, Grijalva Israel, Escalante-Santiago David, Orozco-Suarez Sand |
| A Prediction Algorithm for Drug Response in Patients with Mesial Temporal Lobe Epilepsy Based on Clinical and Genetic Information. PloS one 2017 12 (1): e0169214. Silva-Alves Mariana S, Secolin Rodrigo, Carvalho Benilton S, Yasuda Clarissa L, Bilevicius Elizabeth, Alvim Marina K M, Santos Renato O, Maurer-Morelli Claudia V, Cendes Fernando, Lopes-Cendes Isc |
| Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain. Acta neurologica Scandinavica 2015 Jul . Noai M, Soraoka H, Kajiwara A, Tanamachi Y, Oniki K, Nakagawa K, Ishitsu T, Saruwatari |
| CYP2C9, CYP2C19, ABCB1 genetic polymorphisms and phenytoin plasma concentrations in Mexican-Mestizo patients with epilepsy. The pharmacogenomics journal 2015 Jun . Ortega-Vázquez A, Dorado P, Fricke-Galindo I, Jung-Cook H, Monroy-Jaramillo N, Martínez-Juárez I E, Familiar-López I, Peñas-Lledó E, LLerena A, López-López |
| Individualized phenytoin therapy for Japanese pediatric patients with epilepsy based on CYP2C9 and CYP2C19 genotypes. Therapeutic drug monitoring 2015 Apr 37 (2): 229-35. Yamamoto Yoshiaki, Takahashi Yukitoshi, Imai Katsumi, Miyakawa Kou, Ikeda Hiroko, Ueda Yuki, Yamaguchi Tokito, Nasu Hirosato, Ohtani Hideyuki, Shigematsu Hideo, Kagawa Yoshiyuki, Inoue Yus |
| The effect of polymorphic metabolism enzymes on serum phenytoin level. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2015 Mar 36 (3): 397-401. Ozkaynakci Aydan, Gulcebi Medine Idrizoglu, Ergeç Deniz, Ulucan Korkut, Uzan Mustafa, Ozkara Cigdem, Guney Ilter, Onat Filiz Yilm |
| Effect of CYP2C19 polymorphisms on the clinical outcome of low-dose clobazam therapy in Japanese patients with epilepsy. European journal of clinical pharmacology 2015 Jan 71 (1): 51-8. Hashi Sachiyo, Yano Ikuko, Shibata Mai, Masuda Satohiro, Kinoshita Masako, Matsumoto Riki, Ikeda Akio, Takahashi Ryosuke, Matsubara Kaz |
| Pharmacogenetic evaluation of ABCB1, Cyp2C9, Cyp2C19 and methylene tetrahydrofolate reductase polymorphisms in teratogenicity of anti-epileptic drugs in women with epilepsy. Annals of Indian Academy of Neurology 2014 Jul 17 (3): 259-66. Jose Manna, Banerjee Moinak, Mathew Anila, Bharadwaj Tashi, Vijayan Neetha, Thomas Sanjeev |
| The effect of genetic polymorphisms of cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on drug-resistant epilepsy in Turkish children. Molecular diagnosis & therapy 2014 Apr 18 (2): 229-36. Seven Mehmet, Batar Bahadir, Unal Selin, Yesil Gozde, Yuksel Adnan, Guven Mehm |
| Brivaracetam single and multiple rising oral dose study in healthy Japanese participants: influence of CYP2C19 genotype. Drug metabolism and pharmacokinetics 2014 29 (5): 394-9. Stockis Armel, Watanabe Shikiko, Rouits Elisabeth, Matsuguma Kyoko, Irie Sh |
| Influence of CYP2C19 polymorphism and concomitant antiepileptic drugs on serum clobazam and N-desmethyl clobazam concentrations in patients with epilepsy. Therapeutic drug monitoring 2013 Jun 35 (3): 305-12. Yamamoto Yoshiaki, Takahashi Yukitoshi, Imai Katsumi, Miyakawa Kou, Nishimura Shigeko, Kasai Risa, Ikeda Hiroko, Takayama Rumiko, Mogami Yukiko, Yamaguchi Tokito, Terada Kiyohito, Matsuda Kazumi, Inoue Yushi, Kagawa Yoshiyu |
| Effects of polymorphisms in six candidate genes on phenytoin maintenance therapy in Han Chinese patients. Pharmacogenomics 2012 Sep 13 (12): 1339-49. Hung Chin-Chuan, Huang Hsiao-Ching, Gao Yun-Han, Chang Wei-Lun, Ho Jia-Ling, Chiou Mu-Han, Hsieh Yow-Wen, Liou Horng-Hu |
| Possible role of CYP2C9 & CYP2C19 single nucleotide polymorphisms in drug refractory epilepsy. The Indian journal of medical research 2011 Sep 134 (3): 295-301. Lakhan Ram, Kumari Ritu, Singh Kavita, Kalita Jayanti, Misra Usha Kant, Mittal Balr |
| [Development of rapid genotyping methods for single nucleotide polymorphisms of cytochrome P450 2C9 (CYP2C9) and cytochrome P450 2C19 (CYP2C19) and their clinical application in pediatric patients with epilepsy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011 131 (5): 809-15. Yamamoto Yoshiaki, Takahashi Yukitoshi, Nishimura Shigeko, Ikumi Yasuhiro, Mishima Nobuyuki, Kagawa Yoshiyu |
| Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment. Pharmacogenomics 2010 Jul 11 (7): 927-41. Grover Sandeep, Gourie-Devi Mandaville, Baghel Ruchi, Sharma Sangeeta, Bala Kiran, Gupta Meena, Narayanasamy Krishnamoorthy, Varma Binuja, Gupta Meenal, Kaur Kavita, Talwar Puneet, Kaur Harpreet, Giddaluru Sudheer, Sharma Abhay, Brahmachari Samir K, Indian Genome Variation Consortium , Kukreti Ritushr |
| Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients. European journal of clinical pharmacology 2010 Jul 66 (7): 689-96. Kesavan Ramasamy, Narayan Sunil K, Adithan Chandrasekar |
| Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy. Seizure 2010 Mar 19 (2): 93-101. Sánchez M Blanca, Herranz José L, Leno Carlos, Arteaga Rosa, Oterino Agustín, Valdizán Elsa M, Nicolás José M, Adín Javier, Armijo Juan |
| Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy. Pharmacogenetics and genomics 2009 May 19 (5): 353-62. Ufer Mike, Mosyagin Igor, Muhle Hiltrud, Jacobsen Thies, Haenisch Sierk, Häsler Robert, Faltraco Frank, Remmler Cornelia, von Spiczak Sarah, Kroemer Heyo K, Runge Uwe, Boor Rainer, Stephani Ulrich, Cascorbi Ingo |
| Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. Pharmacotherapy 2008 Jan 28 (1): 35-41. Lin Chun-Jung, Yen Ming-Fang, Hu Oliver Yoa-Pu, Lin Min-Shung, Hsiong Cheng-Huei, Hung Chin-Chuan, Liou Horng-Hu |
| [Association between genetic polymorphisms of CYP2C19 and CYP2C9 and phenytoin serum concentration]. Zhonghua yi xue za zhi 2004 Oct 84 (20): 1686-9. Huang Yue, Yang Jing-Fang, Qi Xiao-Lian, Wang Yu-Qin, Wang Wei-Zhi, Chen Bi |
| Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms. Therapeutic drug monitoring 2004 Oct 26 (5): 534-40. Hung Chin-Chuan, Lin Chun-Jung, Chen Chih-Chuan, Chang Chee-Jen, Liou Horng-Hu |
| Association of polymorphisms of CYP2C9, CYP2C19, and ABCB1, and activity of P-glycoprotein with response to anti-epileptic drugs. Journal of postgraduate medicine 0 60 (3): 265-9. Taur S R, Kulkarni N B, Gandhe P P, Thelma B K, Ravat S H, Gogtay N J, Thatte U |
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- Page last updated:Oct 18, 2021
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