HuGE Literature Finder
Records 1-39
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Phase II study of high-sensitivity genotyping of KRAS, NRAS, BRAF and PIK3CA to ultra-select metastatic colorectal cancer patients for panitumumab plus FOLFIRI: the ULTRA trial.
Annals of oncology : official journal of the European Society for Medical Oncology 2019 Mar . Santos C, Azuara D, Viéitez J M, Páez D, Falcó E, Élez E, López-López C, Valladares M, Robles-Díaz L, García-Alfonso P, Bugés C, Durán G, Salud A, Navarro V, Capellá G, Salazar R, Aranda |
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Somatic genetic alterations in synchronous and metachronous low-grade serous tumours and high-grade carcinomas of the adnexa.
Histopathology 2019 Mar 74 (4): 638-650. Murali Rajmohan, Selenica Pier, Brown David N, Cheetham R Keira, Chandramohan Raghu, Claros Nidia L, Bouvier Nancy, Cheng Donavan T, Soslow Robert A, Weigelt Britta, McCluggage W Gle |
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TERTp mutation is associated with a shorter progression free survival in patients with aggressive histology subtypes of follicular-cell derived thyroid carcinoma.
Endocrine 2018 Jun . Penna Gustavo C, Pestana Ana, Cameselle José Manuel, Momesso Denise, de Andrade Fernanda Accioly, Vidal Ana Paula Aguiar, Araujo Junior Mario Lucio, Melo Miguel, Fernandes Priscila Valverde, Corbo Rossana, Vaisman Mario, Sobrinho-Simões Manuel, Soares Paula, Vaisman Fernan |
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Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 01 29 (1): 145-153. Fribbens C, Garcia Murillas I, Beaney M, Hrebien S, O'Leary B, Kilburn L, Howarth K, Epstein M, Green E, Rosenfeld N, Ring A, Johnston S, Turner |
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Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and are Primed for Neoplastic Progression.
Molecular cancer research : MCR 2017 Dec . Drew David A, Mo Allen, Grady James J, Stevens Richard G, Levine Joel B, Brenner Bruce M, Anderson Joseph C, Forouhar Faripour, O'Brien Michael J, Devers Thomas J, Rosenberg Daniel |
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Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.
Journal of the National Cancer Institute 2017 Sep 109 (9): . Hong Theodore S, Wo Jennifer Y, Borger Darrell R, Yeap Beow Y, McDonnell Erin I, Willers Henning, Blaszkowsky Lawrence S, Kwak Eunice L, Allen Jill N, Clark Jeffrey W, Tanguturi Shyam, Goyal Lipika, Murphy Janet E, Wolfgang John A, Drapek Lorraine C, Arellano Ronald S, Mamon Harvey J, Mullen John T, Tanabe Kenneth K, Ferrone Cristina R, Ryan David P, Iafrate A John, DeLaney Thomas F, Zhu Andrew |
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Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care.
BMC cancer 2017 Aug 17 (1): 536. Heppt Markus V, Siepmann Timo, Engel Jutta, Schubert-Fritschle Gabriele, Eckel Renate, Mirlach Laura, Kirchner Thomas, Jung Andreas, Gesierich Anja, Ruzicka Thomas, Flaig Michael J, Berking Caro |
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Molecular Alterations in Patients with Pulmonary Adenocarcinoma Presenting with Malignant Pleural Effusion at the First Diagnosis.
Acta cytologica 2017 May . Rodriguez Erika F, Shabihkhani Maryam, Carter Jamal, Maleki Zah |
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Targeted next generation sequencing and identification of risk factors in World Health Organization defined atypical chronic myeloid leukemia.
American journal of hematology 2017 Mar . Patnaik Mrinal M, Barraco Daniela, Lasho Terra L, Finke Christy M, Reichard Kaaren, Hoversten Katherine P, Ketterling Rhett P, Gangat Naseema, Tefferi Ayal |
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Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).
Gynecologic oncology 2017 Jan . Spreafico A, Oza A M, Clarke B A, Mackay H J, Shaw P, Butler M, Dhani N C, Lheureux S, Wilson M K, Welch S, Zhang T, Yu C, Stockley T, Siu L L, Kamel-Reid S, Bedard P |
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Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
BMC cancer 2017 01 17 (1): 38. Nakayama Izuma, Shinozaki Eiji, Matsushima Tomohiro, Wakatsuki Takeru, Ogura Mariko, Ichimura Takashi, Ozaka Masato, Takahari Daisuke, Suenaga Mitsukuni, Chin Keisho, Mizunuma Nobuyuki, Yamaguchi Kens |
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Clinicopathological features and clinical outcomes associated with TP53 and BRAF(N)(on-)(V)(600) mutations in cutaneous melanoma patients.
Cancer 2016 Dec . Kim Dae Won, Haydu Lauren E, Joon Aron Y, Bassett Roland L, Siroy Alan E, Tetzlaff Michael T, Routbort Mark J, Amaria Rodabe N, Wargo Jennifer A, McQuade Jennifer L, Kemnade Jan, Hwu Patrick, Woodman Scott E, Roszik Jason, Kim Kevin B, Gershenwald Jeffrey E, Lazar Alexander J, Davies Michael |
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Frequency of EGFR T790M mutation and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tyrosine kinase inhibitors in Japanese patients.
BMC cancer 2016 Nov 16 (1): 864. Ko Ryo, Kenmotsu Hirotsugu, Serizawa Masakuni, Koh Yasuhiro, Wakuda Kazushige, Ono Akira, Taira Tetsuhiko, Naito Tateaki, Murakami Haruyasu, Isaka Mitsuhiro, Endo Masahiro, Nakajima Takashi, Ohde Yasuhisa, Yamamoto Nobuyuki, Takahashi Kazuhisa, Takahashi Toshia |
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Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Gut 2016 Sep . Sievers Chelsie K, Zou Luli S, Pickhardt Perry J, Matkowskyj Kristina A, Albrecht Dawn M, Clipson Linda, Bacher Jeffery W, Pooler B Dustin, Moawad Fouad J, Cash Brooks D, Reichelderfer Mark, Vo Tien N, Newton Michael A, Larget Bret R, Halberg Richard |
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Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features.
Oncotarget 2016 Jul . Palomo Laura, Garcia Olga, Arnan Montse, Xicoy Blanca, Fuster Francisco, Cabezón Marta, Coll Rosa, Ademà Vera, Grau Javier, Jiménez Maria-José, Pomares Helena, Marcé Sílvia, Mallo Mar, Millá Fuensanta, Alonso Esther, Sureda Anna, Gallardo David, Feliu Evarist, Ribera Josep-Maria, Solé Francesc, Zamora Lurd |
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Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma - occurence and prognostic significance.
Oncotarget 2016 Jun . Módos Orsolya, Reis Henning, Niedworok Christian, Rübben Herbert, Szendröi Attila, Szász Marcell A, Tímár József, Baghy Kornélia, Kovalszky Ilona, Golabek Tomasz, Chlosta Piotr, Okon Krzysztof, Peyronnet Benoit, Mathieu Romain, Shariat Shahrokh F, Hollósi Péter, Nyirády Péter, Szarvas Tib |
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Multi-region whole-exome sequencing uncovers the genetic evolution and mutational heterogeneity of early-stage metastatic melanoma.
Cancer research 2016 May . Harbst Katja, Lauss Martin, Cirenajwis Helena, Isaksson Karolin, Rosengren Frida, Torngren Therese, Kvist Anders, Johansson Maria C, Vallon-Christersson Johan, Baldetorp Bo, Borg Ake, Olsson Håkan, Ingvar Christian, Carneiro Ana, Jonsson Gor |
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Predictive value of somatic mutations for the development of malignancy in thyroid nodules benign by cytopathology.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2016 May . Halászlaki Csaba, Tóbiás Bálint, Balla Bernadett, Kósa János P, Horányi János, Bölöny Eszter, Nagy Zsolt, Speer Gábor, Járay Balázs, Székely Eszter, Istók Roland, Székely Tamás, Putz Zsuzsanna, Dank Magdolna, Lakatos Péter, Takács Istv |
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Recurrent NRAS mutations in pulmonary Langerhans cell histiocytosis.
The European respiratory journal 2016 Apr . Mourah Samia, How-Kit Alexandre, Meignin Véronique, Gossot Dominique, Lorillon Gwenaël, Bugnet Emmanuelle, Mauger Florence, Lebbe Celeste, Chevret Sylvie, Tost Jörg, Tazi Abdellat |
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Highly concordant key genetic alterations in primary tumors and matched distant metastases in differentiated thyroid cancer.
Thyroid : official journal of the American Thyroid Association 2016 Mar . Sohn Seo Young, Park Woong Yang, Shin Hyun-Tae, Bae Joon Seol, Ki Chang-Seok, Oh Young Lyun, Kim Sun Wook, Chung Jae Ho |
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Efficacy of continued cetuximab for unresectable metastatic colorectal cancer after disease progression during first-line cetuximab-based chemotherapy: a retrospective cohort study.
Oncotarget 2016 Feb . Feng Qingyang, Wei Ye, Ren Li, Zheng Peng, Yu Yiyi, Ye Qinghai, Ding Jianyong, Chen Jingwen, Chang Wenju, Zhong Yunshi, Zhu Dexiang, Lin Qi, Yang Liangliang, Qin Xinyu, Xu Jianm |
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Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms.
European journal of cancer (Oxford, England : 1990) 2015 Dec 51 (18): 2792-9. Johnson Douglas B, Menzies Alexander M, Zimmer Lisa, Eroglu Zeynep, Ye Fei, Zhao Shilin, Rizos Helen, Sucker Antje, Scolyer Richard A, Gutzmer Ralf, Gogas Helen, Kefford Richard F, Thompson John F, Becker Jürgen C, Berking Carola, Egberts Friederike, Loquai Carmen, Goldinger Simone M, Pupo Gulietta M, Hugo Willy, Kong Xiangju, Garraway Levi A, Sosman Jeffrey A, Ribas Antoni, Lo Roger S, Long Georgina V, Schadendorf Di |
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Analysis of somatic mutations in braf, CDKN2A/p16 and PI3KCA in patients with medullary thyroid carcinoma.
Molecular medicine reports 2015 Dec . Nascimento Fabrício P, Cardoso Mirian G, Lindsey Susan C, Kunii Ilda S, Valente Flávia O F, Kizys Marina M L, Delcelo Rosana, Camacho Cléber P, Maciel Rui M B, Dias-Da-Silva Magnus |
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Disease kinetics but not disease burden is relevant for survival in melanoma of unknown primary tumor.
Discovery medicine 2015 Oct 20 (110): 231-7. Heppt Markus V, Tietze Julia K, Reinholz Markus, Rahimi Farnaz, Jung Andreas, Kirchner Thomas, Ruzicka Thomas, Flaig Michael J, Berking Caro |
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Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.
Pigment cell & melanoma research 2014 Nov 27 (6): 1117-25. Mar Victoria J, Wong Stephen Q, Logan Aleksandra, Nguyen Trung, Cebon Jonathan, Kelly John W, Wolfe Rory, Dobrovic Alexander, McLean Catriona, McArthur Grant |
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Optimizing single agent panitumumab therapy in pre-treated advanced colorectal cancer.
Neoplasia (New York, N.Y.) 2014 Sep 16 (9): 751-6. Gasparini Giampietro, Buttitta Fiamma, D'Andrea Mario Rosario, Tumolo Salvatore, Buonadonna Angela, Pavese Ida, Cordio Stefano, De Tursi Michele, Mosconi Stefania, Stumbo Luciano, Felicioni Lara, Marchetti Anton |
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Concomitant RAS, RET/PTC, or BRAF mutations in advanced stage of papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association 2014 Aug 24 (8): 1256-66. Zou Minjing, Baitei Essa Y, Alzahrani Ali S, BinHumaid Faisal S, Alkhafaji Dania, Al-Rijjal Roua A, Meyer Brian F, Shi Yuf |
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Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome.
Blood cancer journal 2014 4 e177. Chen T-C, Hou H-A, Chou W-C, Tang J-L, Kuo Y-Y, Chen C-Y, Tseng M-H, Huang C-F, Lai Y-J, Chiang Y-C, Lee F-Y, Liu M-C, Liu C-W, Liu C-Y, Yao M, Huang S-Y, Ko B-S, Hsu S-C, Wu S-J, Tsay W, Chen Y-C, Tien H |
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Assessment of clinical parameters associated with mutational status in metastatic malignant melanoma: a single-centre investigation of 141 patients.
The British journal of dermatology 2013 Apr 168 (4): 708-16. Schlaak M, Bajah A, Podewski T, Kreuzberg N, von Bartenwerffer W, Wardelmann E, Merkelbach-Bruse S, Büttner R, Mauch C, Kurschat |
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The role of CCND1 alterations during the progression of cutaneous malignant melanoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012 Dec 33 (6): 2189-99. Vízkeleti Laura, Ecsedi Szilvia, Rákosy Zsuzsa, Orosz Adrienn, Lázár Viktória, Emri Gabriella, Koroknai Viktória, Kiss Tímea, Ádány Róza, Balázs Marg |
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Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Proceedings of the National Academy of Sciences of the United States of America 2012 Jul 109 (31): E2127-33. Ohashi Kadoaki, Sequist Lecia V, Arcila Maria E, Moran Teresa, Chmielecki Juliann, Lin Ya-Lun, Pan Yumei, Wang Lu, de Stanchina Elisa, Shien Kazuhiko, Aoe Keisuke, Toyooka Shinichi, Kiura Katsuyuki, Fernandez-Cuesta Lynnette, Fidias Panos, Yang James Chih-Hsin, Miller Vincent A, Riely Gregory J, Kris Mark G, Engelman Jeffrey A, Vnencak-Jones Cindy L, Dias-Santagata Dora, Ladanyi Marc, Pao Willi |
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Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Apr 18 (7): 2056-65. Hayes D Neil, Lucas Amy S, Tanvetyanon Tawee, Krzyzanowska Monika K, Chung Christine H, Murphy Barbara A, Gilbert Jill, Mehra Ranee, Moore Dominic T, Sheikh Arif, Hoskins Janelle, Hayward Michele C, Zhao Ni, O'Connor Wendi, Weck Karen E, Cohen Roger B, Cohen Ezra E |
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Evaluation of gene mutations beyond KRAS as predictive biomarkers of response to panitumumab in a randomized, phase III monotherapy study of metastatic colorectal cancer (mCRC).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): 3530. Oliner K, Peeters M, Siena S, Van Cutsem E, Huang J, Humblet Y, Van Laethem J, Andre T, Wiezorek J S, Patterson S |
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Clinical correlates of NRAS and BRAF mutations in primary human melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Jan 17 (2): 229-35. Ellerhorst Julie A, Greene Victoria R, Ekmekcioglu Suhendan, Warneke Carla L, Johnson Marcella M, Cooke Carolyn P, Wang Li-E, Prieto Victor G, Gershenwald Jeffrey E, Wei Qingyi, Grimm Elizabeth |
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ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia.
British journal of haematology 2010 Nov 151 (4): 365-75. Gelsi-Boyer Véronique, Trouplin Virginie, Roquain Julien, Adélaïde José, Carbuccia Nadine, Esterni Benjamin, Finetti Pascal, Murati Anne, Arnoulet Christine, Zerazhi Hacène, Fezoui Hacène, Tadrist Zoulika, Nezri Meyer, Chaffanet Max, Mozziconacci Marie-Joëlle, Vey Norbert, Birnbaum Dani |
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Multiple genetic alterations in papillary thyroid cancer are associated with younger age at presentation.
The Journal of surgical research 2010 May 160 (2): 179-83. Moses Willieford, Weng Julie, Khanafshar Elham, Duh Quan-Yang, Clark Orlo H, Kebebew Electr |
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Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma.
The Journal of investigative dermatology 2009 Jun 129 (6): 1483-8. Greene Victoria R, Johnson Marcella M, Grimm Elizabeth A, Ellerhorst Julie |
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Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.
Cancer research 2009 Jun 69 (11): 4885-93. Ricarte-Filho Julio C, Ryder Mabel, Chitale Dhananjay A, Rivera Michael, Heguy Adriana, Ladanyi Marc, Janakiraman Manickam, Solit David, Knauf Jeffrey A, Tuttle R Michael, Ghossein Ronald A, Fagin James |
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A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia.
Haematologica 2007 Jun 92 (6): 744-52. Bacher Ulrike, Haferlach Torsten, Kern Wolfgang, Haferlach Claudia, Schnittger Susan |
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- Page last updated:Jan 16, 2020
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