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Polygenic Scores of Alzheimer's Disease Risk Genes Add Only Modestly to APOE in Explaining Variation in Amyloid PET Burden. Journal of Alzheimer's disease : JAD 2022 Jul . Ramanan Vijay K, Heckman Michael G, Przybelski Scott A, Lesnick Timothy G, Lowe Val J, Graff-Radford Jonathan, Mielke M, Jack Clifford R, Knopman David S, Petersen Ronald C, Ross Owen A, Vemuri Prashanthi, |
Risk Variants in Three Alzheimer's Disease Genes Show Association with EEG Endophenotypes. Journal of Alzheimer's disease : JAD 2021 Jan . Macedo Ana, Gómez Carlos, Rebelo Miguel Ângelo, Poza Jesús, Gomes Iva, Martins Sandra, Maturana-Candelas Aarón, Pablo Víctor Gutiérrez-de, Durães Luis, Sousa Patrícia, Figueruelo Manuel, Rodriguez Maria, Pita Carmen, Arenas Miguel, Alvarez Luís, Hornero Roberto, Lopes Alexandra M, Pinto Nád |
Association of rare variants in neurodegenerative genes with familial Alzheimer's disease. Annals of clinical and translational neurology 2020 Sep . Zhang Weiwei, Jiao Bin, Xiao Tingting, Liu Xixi, Liao Xinxin, Xiao Xuewen, Guo Lina, Yuan Zhenhua, Yan Xinxiang, Tang Beisha, Shen |
Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls. Neurologia (Barcelona, Spain) 2018 Nov . Cruz-Sanabria F, Bonilla-Vargas K, Estrada K, Mancera O, Vega E, Guerrero E, Ortega-Rojas J, Mahecha María F, Romero A, Montañés P, Celeita V, Arboleda H, Pardo |
Alzheimer's disease susceptibility genes modify the risk of Parkinson disease and Parkinson's disease-associated cognitive impairment. Neuroscience letters 2018 Apr 677 55-59. Fang Lu, Tang Bei-Sha, Fan Kuan, Wan Chang-Min, Yan Xin-Xiang, Guo Ji-Fe |
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Annals of clinical and translational neurology 2018 Apr 5 (4): 406-417. Vardarajan Badri N, Barral Sandra, Jaworski James, Beecham Gary W, Blue Elizabeth, Tosto Giuseppe, Reyes-Dumeyer Dolly, Medrano Martin, Lantigua Rafael, Naj Adam, Thornton Timothy, DeStefano Anita, Martin Eden, Wang Li-San, Brown Lisa, Bush William, van Duijn Cornelia, Goate Allison, Farrer Lindsay, Haines Jonathan L, Boerwinkle Eric, Schellenberg Gerard, Wijsman Ellen, Pericak-Vance Margaret A, Mayeux Richard, , Wang Li-S |
Associations of polymorphisms in the candidate genes for Alzheimer's disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance. Molecular biology reports 2017 Mar . Vacínová Gabriela, Vejražková D, Lukášová P, Lischková O, Dvo?áková K, Rusina R, Holmerová I, Va?ková H, V?elák J, Bendlová B, Va?ková |
Relation of genomic variants for Alzheimer disease dementia to common neuropathologies. Neurology 2016 Jul . Farfel Jose M, Yu Lei, Buchman Aron S, Schneider Julie A, De Jager Philip L, Bennett David |
Association of genetic risk factors with cognitive decline: the PATH through life project. Neurobiology of aging 2016 May 41 150-8. Andrews Shea J, Das Debjani, Cherbuin Nicolas, Anstey Kaarin J, Easteal Sim |
Lower Prevalence of Alzheimer's Disease among Tibetans: Association with Religious and Genetic Factors. Journal of Alzheimer's disease : JAD 2016 Jan . Huang Fukai, Shang Ying, Luo Yuandai, Wu Peng, Huang Xue, Tan Xiaohui, Lu Xingyi, Zhen Lifang, Hu Xian |
Relationship between Alzheimer's disease GWAS-linked top hits and risk of Parkinson's disease with or without cognitive decline: a Chinese population-based study. Neurobiology of aging 2015 Dec . Wang Ya-Qin, Tang Bei-Sha, Yang Yang, Cui Yi-Ting, Kang Ji-Feng, Liu Zhen-Hua, Li Kai, Sun Qi-Ying, Xu Qian, Yan Xin-Xiang, Guo Ji-Fe |
Association of Alzheimer's related genotypes with cognitive decline in multiple domains: results from the Three-City Dijon study. Molecular psychiatry 2015 Oct 20 (10): 1173-8. Vivot A, Glymour M M, Tzourio C, Amouyel P, Chêne G, Dufouil |
A novel Alzheimer disease locus located near the gene encoding tau protein.
![]() Molecular psychiatry 2015 Mar . Jun G, Ibrahim-Verbaas C A, Vronskaya M, Lambert J-C, Chung J, Naj A C, Kunkle B W, Wang L-S, Bis J C, Bellenguez C, Harold D, Lunetta K L, Destefano A L, Grenier-Boley B, Sims R, Beecham G W, Smith A V, Chouraki V, Hamilton-Nelson K L, Ikram M A, Fievet N, Denning N, Martin E R, Schmidt H, Kamatani Y, Dunstan M L, Valladares O, Laza A R, Zelenika D, Ramirez A, Foroud T M, Choi S-H, Boland A, Becker T, Kukull W A, van der Lee S J, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick A L, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett D A, Amin N, Berr C, Tsolaki Magda, Buxbaum J D, Lopez O L, Deramecourt V, Fox N C, Cantwell L B, Tárraga L, Dufouil C, Hardy J, Crane P K, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley T H, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues J-F, Hampel H, Kamboh M I, de Bruijn R F A G, Tzourio C, Pastor P, Larson E B, Rotter J I, O'Donovan M C, Montine T J, Nalls M A, Mead S, Reiman E M, Jonsson P V, Holmes C, St George-Hyslop P H, Boada M, Passmore P, Wendland J R, Schmidt R, Morgan K, Winslow A R, Powell J F, Carasquillo M, Younkin S G, Jakobsdóttir J, Kauwe J S K, Wilhelmsen K C, Rujescu D, Nöthen M M, Hofman A, Jones L, , Haines J L, Psaty B M, Van Broeckhoven C, Holmans P, Launer L J, Mayeux R, Lathrop M, Goate A M, Escott-Price V, Seshadri S, Pericak-Vance M A, Amouyel P, Williams J, van Duijn C M, Schellenberg G D, Farrer L |
Association of MTHFR and PICALM polymorphisms with Alzheimer's disease. Molecular biology reports 2015 Mar 42 (3): 611-6. Belcavello Luciano, Camporez Daniela, Almeida Leila D, Morelato Renato L, Batitucci Maria C P, de Paula Flav |
Genetic evidence for the involvement of variants at APOE, BIN1, CR1, and PICALM loci in risk of late-onset Alzheimer's disease and evaluation for interactions with APOE genotypes. Journal of molecular neuroscience : MN 2014 Dec 54 (4): 780-6. Gharesouran Jalal, Rezazadeh Maryam, Khorrami Aziz, Ghojazadeh Morteza, Talebi Mahn |
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
![]() PLoS genetics 2014 Sep 10 (9): e1004606. Beecham Gary W, Hamilton Kara, Naj Adam C, Martin Eden R, Huentelman Matt, Myers Amanda J, Corneveaux Jason J, Hardy John, Vonsattel Jean-Paul, Younkin Steven G, Bennett David A, De Jager Philip L, Larson Eric B, Crane Paul K, Kamboh M Ilyas, Kofler Julia K, Mash Deborah C, Duque Linda, Gilbert John R, Gwirtsman Harry, Buxbaum Joseph D, Kramer Patricia, Dickson Dennis W, Farrer Lindsay A, Frosch Matthew P, Ghetti Bernardino, Haines Jonathan L, Hyman Bradley T, Kukull Walter A, Mayeux Richard P, Pericak-Vance Margaret A, Schneider Julie A, Trojanowski John Q, Reiman Eric M, , Schellenberg Gerard D, Montine Thomas |
Genetic variants conferring susceptibility to Alzheimer's disease in the general population; do they also predispose to dementia in Down's syndrome. BMC research notes 2014 7 (1): 42. Patel Ashok, Rees Simon D, Kelly M Ann, Bain Stephen C, Barnett Anthony H, Prasher Anisha, Arshad Humaria, Prasher Vee |
Effect of Alzheimer's disease risk genes on trajectories of cognitive function in the Cardiovascular Health Study. The American journal of psychiatry 2012 Sep 169 (9): 954-62. Sweet Robert A, Seltman Howard, Emanuel James E, Lopez Oscar L, Becker James T, Bis Joshua C, Weamer Elise A, DeMichele-Sweet Mary Ann A, Kuller Lewis |
Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains. PloS one 2012 7 (11): e50976. Karch Celeste M, Jeng Amanda T, Nowotny Petra, Cady Janet, Cruchaga Carlos, Goate Alison |
Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.
![]() Translational psychiatry 2011 Nov 1 e54. Hu X, Pickering E H, Hall S K, Naik S, Liu Y C, Soares H, Katz E, Paciga S A, Liu W, Aisen P S, Bales K R, Samad T A, John S |
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
![]() PLoS genetics 2011 Feb 7 (2): e1001308. Wijsman Ellen M, Pankratz Nathan D, Choi Yoonha, Rothstein Joseph H, Faber Kelley M, Cheng Rong, Lee Joseph H, Bird Thomas D, Bennett David A, Diaz-Arrastia Ramon, Goate Alison M, Farlow Martin, Ghetti Bernardino, Sweet Robert A, Foroud Tatiana M, Mayeux Richard, |
An exploratory study on CLU, CR1 and PICALM and Parkinson disease. PloS one 2011 6 (8): e24211. Gao Jianjun, Huang Xuemei, Park Yikyung, Hollenbeck Albert, Chen Hongl |
Genetic association of sequence variants near AGER/NOTCH4 and dementia. Journal of Alzheimer's disease : JAD 2011 24 (3): 475-84. Bennet Anna M, Reynolds Chandra A, Eriksson Ulrika K, Hong Mun-Gwan, Blennow Kaj, Gatz Margaret, Alexeyenko Andrey, Pedersen Nancy L, Prince Jonathan |
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
![]() PloS one 2011 6 (2): e16616. Hu Xiaolan, Pickering Eve, Liu Yingxue Cathy, Hall Stephanie, Fournier Helene, Katz Elyse, Dechairo Bryan, John Sally, Van Eerdewegh Paul, Soares Holly, |
PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients. Journal of Alzheimer's disease : JAD 2011 25 (1): 111-7. Li Hong-Lei, Shi Sheng-Sheng, Guo Qi-Hao, Ni Wang, Dong Yi, Liu Ying, Sun Yi-Min, Bei-Wang , Lu Shen-Ji, Hong Zhen, Wu Zhi-Yi |
Replication of CLU, CR1, and PICALM associations with alzheimer disease. Archives of neurology 2010 Aug 67 (8): 961-4. Carrasquillo Minerva M, Belbin Olivia, Hunter Talisha A, Ma Li, Bisceglio Gina D, Zou Fanggeng, Crook Julia E, Pankratz V Shane, Dickson Dennis W, Graff-Radford Neill R, Petersen Ronald C, Morgan Kevin, Younkin Steven |
Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls. Neurologia (Barcelona, Spain) 0 36 (9): 681-691. Cruz-Sanabria F, Bonilla-Vargas K, Estrada K, Mancera O, Vega E, Guerrero E, Ortega-Rojas J, Mahecha María F, Romero A, Montañés P, Celeita V, Arboleda H, Pardo |
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- Page last updated:Aug 16, 2022
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