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Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
Nature genetics 2022 Feb . Barc Julien, Tadros Rafik, Glinge Charlotte, Chiang David Y, Jouni Mariam, Simonet Floriane, Jurgens Sean J, Baudic Manon, Nicastro Michele, Potet Franck, Offerhaus Joost A, Walsh Roddy, Choi Seung Hoan, Verkerk Arie O, Mizusawa Yuka, Anys Soraya, Minois Damien, Arnaud Marine, Duchateau Josselin, Wijeyeratne Yanushi D, Muir Alison, Papadakis Michael, Castelletti Silvia, Torchio Margherita, Ortuño Cristina Gil, Lacunza Javier, Giachino Daniela F, Cerrato Natascia, Martins Raphaël P, Campuzano Oscar, Van Dooren Sonia, Thollet Aurélie, Kyndt Florence, Mazzanti Andrea, Clémenty Nicolas, Bisson Arnaud, Corveleyn Anniek, Stallmeyer Birgit, Dittmann Sven, Saenen Johan, Noël Antoine, Honarbakhsh Shohreh, Rudic Boris, Marzak Halim, Rowe Matthew K, Federspiel Claire, Le Page Sophie, Placide Leslie, Milhem Antoine, Barajas-Martinez Hector, Beckmann Britt-Maria, Krapels Ingrid P, Steinfurt Johannes, Winkel Bo Gregers, Jabbari Reza, Shoemaker Moore B, Boukens Bas J, Škori?-Milosavljevi? Doris, Bikker Hennie, Manevy Federico, Lichtner Peter, Ribasés Marta, Meitinger Thomas, Müller-Nurasyid Martina, , Veldink Jan H, van den Berg Leonard H, Van Damme Philip, Cusi Daniele, Lanzani Chiara, Rigade Sidwell, Charpentier Eric, Baron Estelle, Bonnaud Stéphanie, Lecointe Simon, Donnart Audrey, Le Marec Hervé, Chatel Stéphanie, Karakachoff Matilde, Bézieau Stéphane, London Barry, Tfelt-Hansen Jacob, Roden Dan, Odening Katja E, Cerrone Marina, Chinitz Larry A, Volders Paul G, van de Berg Maarten P, Laurent Gabriel, Faivre Laurence, Antzelevitch Charles, Kääb Stefan, Arnaout Alain Al, Dupuis Jean-Marc, Pasquie Jean-Luc, Billon Olivier, Roberts Jason D, Jesel Laurence, Borggrefe Martin, Lambiase Pier D, Mansourati Jacques, Loeys Bart, Leenhardt Antoine, Guicheney Pascale, Maury Philippe, Schulze-Bahr Eric, Robyns Tomas, Breckpot Jeroen, Babuty Dominique, Priori Silvia G, Napolitano Carlo, , de Asmundis Carlo, Brugada Pedro, Brugada Ramon, Arbelo Elena, Brugada Josep, Mabo Philippe, Behar Nathalie, Giustetto Carla, Molina Maria Sabater, Gimeno Juan R, Hasdemir Can, Schwartz Peter J, Crotti Lia, McKeown Pascal P, Sharma Sanjay, Behr Elijah R, Haissaguerre Michel, Sacher Frédéric, Rooryck Caroline, Tan Hanno L, Remme Carol A, Postema Pieter G, Delmar Mario, Ellinor Patrick T, Lubitz Steven A, Gourraud Jean-Baptiste, Tanck Michael W, George Alfred L, MacRae Calum A, Burridge Paul W, Dina Christian, Probst Vincent, Wilde Arthur A, Schott Jean-Jacques, Redon Richard, Bezzina Connie |
| GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations.
PloS one 2019 14 (6): e0217796. Swenson Brenton R, Louie Tin, Lin Henry J, Méndez-Giráldez Raúl, Below Jennifer E, Laurie Cathy C, Kerr Kathleen F, Highland Heather, Thornton Timothy A, Ryckman Kelli K, Kooperberg Charles, Soliman Elsayed Z, Seyerle Amanda A, Guo Xiuqing, Taylor Kent D, Yao Jie, Heckbert Susan R, Darbar Dawood, Petty Lauren E, McKnight Barbara, Cheng Susan, Bello Natalie A, Whitsel Eric A, Hanis Craig L, Nalls Mike A, Evans Daniel S, Rotter Jerome I, Sofer Tamar, Avery Christy L, Sotoodehnia No |
| Associations between common ion channel single nucleotide polymorphisms and sudden cardiac death in adults: A MOOSE-compliant meta-analysis. Medicine 2018 Sep 97 (38): e12428. Liu Xiaoli, Shi Jianli, Xiao Peil |
| GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals.
Scientific reports 2017 Dec 7 (1): 17075. Méndez-Giráldez Raúl, Gogarten Stephanie M, Below Jennifer E, Yao Jie, Seyerle Amanda A, Highland Heather M, Kooperberg Charles, Soliman Elsayed Z, Rotter Jerome I, Kerr Kathleen F, Ryckman Kelli K, Taylor Kent D, Petty Lauren E, Shah Sanjiv J, Conomos Matthew P, Sotoodehnia Nona, Cheng Susan, Heckbert Susan R, Sofer Tamar, Guo Xiuqing, Whitsel Eric A, Lin Henry J, Hanis Craig L, Laurie Cathy C, Avery Christy |
| Ethnic Differences in Genetic Ion Channelopathies Associated with Sudden Cardiac Death: A Systematic Review and Meta-Analysis. Annals of clinical and laboratory science 2017 Aug 47 (4): 481-490. Kong Tim, Feulefack Joseph, Ruether Kim, Shen Fan, Zheng Wang, Chen Xing-Zhen, Sergi Consola |
| 52 Genetic Loci Influencing Myocardial Mass.
Journal of the American College of Cardiology 2016 Sep 68 (13): 1435-1448. van der Harst Pim, van Setten Jessica, Verweij Niek, Vogler Georg, Franke Lude, Maurano Matthew T, Wang Xinchen, Mateo Leach Irene, Eijgelsheim Mark, Sotoodehnia Nona, Hayward Caroline, Sorice Rossella, Meirelles Osorio, Lyytikäinen Leo-Pekka, Polašek Ozren, Tanaka Toshiko, Arking Dan E, Ulivi Sheila, Trompet Stella, Müller-Nurasyid Martina, Smith Albert V, Dörr Marcus, Kerr Kathleen F, Magnani Jared W, Del Greco M Fabiola, Zhang Weihua, Nolte Ilja M, Silva Claudia T, Padmanabhan Sandosh, Tragante Vinicius, Esko Tõnu, Abecasis Gonçalo R, Adriaens Michiel E, Andersen Karl, Barnett Phil, Bis Joshua C, Bodmer Rolf, Buckley Brendan M, Campbell Harry, Cannon Megan V, Chakravarti Aravinda, Chen Lin Y, Delitala Alessandro, Devereux Richard B, Doevendans Pieter A, Dominiczak Anna F, Ferrucci Luigi, Ford Ian, Gieger Christian, Harris Tamara B, Haugen Eric, Heinig Matthias, Hernandez Dena G, Hillege Hans L, Hirschhorn Joel N, Hofman Albert, Hubner Norbert, Hwang Shih-Jen, Iorio Annamaria, Kähönen Mika, Kellis Manolis, Kolcic Ivana, Kooner Ishminder K, Kooner Jaspal S, Kors Jan A, Lakatta Edward G, Lage Kasper, Launer Lenore J, Levy Daniel, Lundby Alicia, Macfarlane Peter W, May Dalit, Meitinger Thomas, Metspalu Andres, Nappo Stefania, Naitza Silvia, Neph Shane, Nord Alex S, Nutile Teresa, Okin Peter M, Olsen Jesper V, Oostra Ben A, Penninger Josef M, Pennacchio Len A, Pers Tune H, Perz Siegfried, Peters Annette, Pinto Yigal M, Pfeufer Arne, Pilia Maria Grazia, Pramstaller Peter P, Prins Bram P, Raitakari Olli T, Raychaudhuri Soumya, Rice Ken M, Rossin Elizabeth J, Rotter Jerome I, Schafer Sebastian, Schlessinger David, Schmidt Carsten O, Sehmi Jobanpreet, Silljé Herman H W, Sinagra Gianfranco, Sinner Moritz F, Slowikowski Kamil, Soliman Elsayed Z, Spector Timothy D, Spiering Wilko, Stamatoyannopoulos John A, Stolk Ronald P, Strauch Konstantin, Tan Sian-Tsung, Tarasov Kirill V, Trinh Bosco, Uitterlinden Andre G, van den Boogaard Malou, van Duijn Cornelia M, van Gilst Wiek H, Viikari Jorma S, Visscher Peter M, Vitart Veronique, Völker Uwe, Waldenberger Melanie, Weichenberger Christian X, Westra Harm-Jan, Wijmenga Cisca, Wolffenbuttel Bruce H, Yang Jian, Bezzina Connie R, Munroe Patricia B, Snieder Harold, Wright Alan F, Rudan Igor, Boyer Laurie A, Asselbergs Folkert W, van Veldhuisen Dirk J, Stricker Bruno H, Psaty Bruce M, Ciullo Marina, Sanna Serena, Lehtimäki Terho, Wilson James F, Bandinelli Stefania, Alonso Alvaro, Gasparini Paolo, Jukema J Wouter, Kääb Stefan, Gudnason Vilmundur, Felix Stephan B, Heckbert Susan R, de Boer Rudolf A, Newton-Cheh Christopher, Hicks Andrew A, Chambers John C, Jamshidi Yalda, Visel Axel, Christoffels Vincent M, Isaacs Aaron, Samani Nilesh J, de Bakker Paul I |
| Common genetic variants associated with sudden cardiac death: the FinSCDgen study. PloS one 2012 7 (7): e41675. Lahtinen Annukka M, Noseworthy Peter A, Havulinna Aki S, Jula Antti, Karhunen Pekka J, Kettunen Johannes, Perola Markus, Kontula Kimmo, Newton-Cheh Christopher, Salomaa Veik |
| Common variants at ten loci influence QT interval duration in the QTGEN Study.
Nature genetics 2009 Apr 41 (4): 4. Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ, Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH |
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