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| Clopidogrel Use in CYP2C19 Loss-of-Function Carriers With High Bleeding Risk After Percutaneous Coronary Intervention. Circulation journal : official journal of the Japanese Circulation Society 2023 2 . Sawayama Yuichi, Tomita Yukinori, Kohyama Soji, Higo Yosuke, Kodama Kenji, Asada Kohei, Yagi Noriaki, Fukuyama Megumi, Hayashi Atsushi, Shioyama Wataru, Sakai Hiroshi, Ozawa Tomoya, Isono Tetsuichiro, Hira Daiki, Yamamoto Takashi, Morita Shin-Ya, Nakagawa Yoshihi |
| Cytochrome P450 2C19 Polymorphisms and Its Association With Major Adverse Cardiac Events in Post-coronary Intervention Patients on Clopidogrel in the Tertiary Care Center. Cureus 2023 3 15 (2): e34737. Kambhampati Nikhil Teja, Ahamed Hisham, K K Velayudhan, David Sachin, Hakeem Sai Chandra, Pillai Gopalakrishna, Kartha Nivedit |
| Antiplatelet and myocardial protective effect of Shexiang Tongxin Dropping Pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial. Journal of integrative medicine 2022 Jan . Lin Yan-Jun, Jiao Kun-Li, Liu Bo, Fang Lu, Meng S |
| Clinical non-effectiveness of clopidogrel use for peripheral artery disease in patients with CYP2C19 polymorphisms: a systematic review. European journal of clinical pharmacology 2022 6 78 (8): 1217-1225. Huang Shu, Yang Seonkyeong, Ly Shirly, Yoo Ryan H, Lo-Ciganic Wei-Hsuan, Eadon Michael T, Schleyer Titus, Whipple Elizabeth, Nguyen Khoa A |
| CYP2C19 genotype and platelet aggregation test-guided dual antiplatelet therapy after off-pump coronary artery bypass grafting: A retrospective cohort study. Frontiers in cardiovascular medicine 2022 12 9 1023004. Yao Haoyi, Qin Kaijie, Liu Yun, Yang Yi, Zhu Jiaxi, Chen Anqing, Wang Zhe, Ye Xiaofeng, Zhou Mi, Li Haiqing, Qiu Jiapei, Zhao Qiang, Zhu Yunpe |
| CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings. Journal of the American Heart Association 2022 2 11 (4): e024159. Beitelshees Amber L, Thomas Cameron D, Empey Philip E, Stouffer George A, Angiolillo Dominick J, Franchi Francesco, Tuteja Sony, Limdi Nita A, Lee James C, Duarte Julio D, Kreutz Rolf P, Skaar Todd C, Coons James C, Giri Jay, McDonough Caitrin W, Rowland Rachel, Stevenson James M, Thai Thuy, Vesely Mark R, Wellen Jacob T, Johnson Julie A, Winterstein Almut G, Cavallari Larisa H, Lee Craig R, |
| CYP2C19 genotype-guided antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease: study design of a randomized controlled trial (GENPAD). American heart journal 2022 8 254 141-148. Kranendonk J, Willems L H, Vijver-Coppen Rj van der, Coenen M, Adang E, Donders R, Zeebregts C J, Deneer Vhm, Reijnen Mmpj, Kramers C, Warlé M |
| Effects of Enzyme Induction and Polymorphism on the Pharmacokinetics of Isoniazid and Rifampin in Tuberculosis/HIV Patients. Antimicrobial agents and chemotherapy 2022 9 66 (10): e0227721. Sundell Jesper, Bienvenu Emile, Birgersson Sofia, Äbelö Angela, Ashton Micha |
| Effects of the CYP2C19 LoF allele on major adverse cardiovascular events associated with clopidogrel in acute coronary syndrome patients undergoing percutaneous coronary intervention: a meta-analysis. Pharmacogenomics 2022 1 23 (3): 207-220. Biswas Mohitosh, Sukasem Chonlaphat, Khatun Kali Most Sumaiya, Ibrahim Baharud |
| Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-Site, Real-World Investigation. Clinical pharmacology and therapeutics 2022 4 112 (1): 146-155. Thomas Cameron D, Franchi Francesco, Keeley Ellen C, Rossi Joseph S, Winget Marshall, David Anderson R, Dempsey Alyssa L, Gong Yan, Gower Megan N, Kerensky Richard A, Kulick Natasha, Malave Jean G, McDonough Caitrin W, Mulrenin Ian R, Starostik Petr, Beitelshees Amber L, Johnson Julie A, Stouffer George A, Winterstein Almut G, Angiolillo Dominick J, Lee Craig R, Cavallari Larisa |
| Safety and Efficacy of CYP2C19 Genotype-Guided Escalation of P2Y Inhibitor Therapy After Percutaneous Coronary Intervention in Chronic Kidney Disease: a Post Hoc Analysis of the TAILOR-PCI Study. Cardiovascular drugs and therapy 2022 11 . Mathew Roy O, Sidhu Mandeep S, Rihal Charanjit S, Lennon Ryan, El-Hajjar Mohammed, Yager Neil, Lyubarova Radmila, Abdul-Nour Khaled, Weitz Steven, O'Cochlain D Fearghas, Murthy Vishakantha, Levisay Justin, Marzo Kevin, Graham John, Dzavik Vlad, So Derek, Goodman Shaun, Rosenberg Yves D, Pereira Naveen, Farkouh Michael |
| Sex-Specific Differences in Clinical Outcomes After Percutaneous Coronary Intervention: Insights from the TAILOR-PCI Trial. Journal of the American Heart Association 2022 6 11 (12): e024709. Madan Mina, Abbott J Dawn, Lennon Ryan, So Derek Y F, MacDougall Andrea M, McLaughlin Mary Ann, Murthy Vishakantha, Saw Jacqueline, Rihal Charanjit, Farkouh Michael E, Pereira Naveen L, Goodman Shaun G, |
| Bedside testing of CYP2C19 vs. conventional clopidogrel treatment to guide antiplatelet therapy in ST-segment elevation myocardial infarction patients. International journal of cardiology 2021 Sep . Al-Rubaish Abdullah M, Al-Muhanna Fahad A, Alshehri Abdullah M, Al-Mansori Mohammed A, Alali Rudaynah A, Khalil Rania M, Al-Faraidy Khalid A, Cyrus Cyril, Sulieman Mohammed M, Vatte Chittibabu, Loza Bao-Li, Claassens Daniel M F, Asselbergs Folkert W, Al-Ali Amein |
| Effects of aging on clinical outcomes in patients receiving genotype-guided P2Y12 inhibitor selection after percutaneous coronary intervention. Pharmacotherapy 2021 Jul . Wood Brian, Lee Craig R, Mulrenin Ian R, Gower Megan N, Rossi Joseph S, Weck Karen E, Stouffer George |
| Clopidogrel in noncarriers of CYP2C19 loss-of-function alleles versus ticagrelor in elderly patients with acute coronary syndrome: A pre-specified sub analysis from the POPular Genetics and POPular Age trials CYP2C19 alleles in elderly patients. International journal of cardiology 2021 Apr . Claassens Daniel M F, Gimbel Marieke E, Bergmeijer Thomas O, Vos Gerrit J A, Hermanides Renicus S, van der Harst Pim, Barbato Emanuele, Morisco Carmine, Tjon Joe Gin Richard M, de Vrey Evelyn A, Heestermans Ton A C M, Jukema J Wouter, von Birgelen Clemens, Waalewijn Reinier A, Hofma Sjoerd H, den Hartog Frank R, Voskuil Michiel, Van't Hof Arnoud W J, Asselbergs Folkert W, Mosterd A, Herrman Jean-Paul R, Dewilde Willem, Mahmoodi Bakhtawar K, Deneer Vera H M, Ten Berg Jurriën |
| Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y Inhibitor Therapy: A Meta-Analysis. JACC. Cardiovascular interventions 2021 Apr 14 (7): 739-750. Pereira Naveen L, Rihal Charanjit, Lennon Ryan, Marcus Gil, Shrivastava Sanskriti, Bell Malcolm R, So Derek, Geller Nancy, Goodman Shaun G, Hasan Ahmed, Lerman Amir, Rosenberg Yves, Bailey Kent, Murad M Hassan, Farkouh Michael |
| Association between CYP2C19 polymorphisms and clinical outcomes in patients undergoing stent procedure for cerebral artery stenosis. Scientific reports 2021 Mar 11 (1): 5974. Li Yan-Jiao, Chen Xuan, Tao Li-Na, Hu Xin-Yuan, Wang Xin-Lu, Song Yan-Qi |
| Impact of genetic variants on clinical outcome after percutaneous coronary intervention in elderly patients. Aging 2021 Mar 13 (5): 6506-6524. Cha Jung-Joon, Park Jae Hyoung, Joo Hyung Joon, Hong Soon Jun, Ahn Tae Hoon, Kim Byeong-Keuk, Shin WonYong, Ahn Sung Gyun, Yoon JungHan, Kim Yong Hoon, Cho Yun-Hyeong, Kang Woong Chol, Kim Weon, Lim Young-Hyo, Gwon Hyeon Cheol, Choi Woong Gil, Lim Do-S |
| Association of CYP2C19 Loss-of-Function Alleles with Major Adverse Cardiovascular Events of Clopidogrel in Stable Coronary Artery Disease Patients Undergoing Percutaneous Coronary Intervention: Meta-analysis. Cardiovascular drugs and therapy 2021 2 35 (6): 1147-1159. Biswas Mohitosh, Kali Sumaiya Khat |
| High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents. Translational stroke research 2021 10 13 (3): 391-398. Lv Huihui, Yang Zidong, Wu Haibo, Liu Mingyuan, Mao Xiaowei, Liu Xu, Ding Hongyan, Shi Zhuqing, Zhou Yang, Liu Qianyun, Zhang Yongkang, Zhou Yinting, Chen Kai, Li Zezhi, Dong Qiang, Ma Jianpeng, Han Y |
| Outcomes of a multi-ethnic Asian population on combined treatment with clopidogrel and omeprazole in 12,440 patients. Journal of thrombosis and thrombolysis 2021 5 52 (3): 925-933. Muthiah Mark D, Zheng Huili, Chew Nicholas W S, Xiao Jieling, Lim Lee Guan, Tan Huay-Cheem, Lee Chi-Hang, Low Adrian F, Foo Ling-Li, Richards A Mark, Dan Yock-Young, Ho K Y, Yip James W L, Chan Mark |
| Short- and long-term cost-effectiveness analysis of CYP2C19 genotype-guided therapy, universal clopidogrel, versus universal ticagrelor in post-percutaneous coronary intervention patients in Qatar. International journal of cardiology 2021 2 331 27-34. AlMukdad Sawsan, Elewa Hazem, Arafa Salaheddin, Al-Badriyeh Dao |
| Utility of a pharmacogenetic-driven algorithm in guiding dual antiplatelet therapy for patients undergoing coronary drug-eluting stent implantation in China. European journal of clinical pharmacology 2021 10 78 (2): 215-225. Lyu Si-Qi, Zhu Jun, Wang Juan, Wu Shuang, Zhang Han, Shao Xing-Hui, Yang Yan-M |
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Clinical pharmacology and therapeutics 2020 May . Verma Shefali Setia, Bergmeijer Thomas O, Gong Li, Reny Jean-Luc, Lewis Joshua P, Mitchell Braxton D, Alexopoulos Dimitrios, Aradi Daniel, Altman Russ B, Bliden Kevin, Bradford Yuki, Campo Gianluca, Chang Kiyuk, Cleator John H, Déry Jean-Pierre, Dridi Nadia P, Fernandez-Cadenas Israel, Fontana Pierre, Gawaz Meinrad, Geisler Tobias, Gensini Gian Franco, Giusti Betti, Gurbel Paul A, Hochholzer Willibald, Holmvang Lene, Kim Eun-Young, Kim Ho-Sook, Marcucci Rossella, Montaner Joan, Backman Joshua D, Pakyz Ruth E, Roden Dan M, Schaeffeler Elke, Schwab Matthias, Shin Jae Gook, Siller-Matula Jolanta M, Ten Berg Jurriën M, Trenk Dietmar, Valgimigli Marco, Wallace John, Wen Ming-Shien, Kubo Michiaki, Lee Ming Ta Michael, Whaley Ryan, Winter Stefan, Klein Teri E, Shuldiner Alan R, Ritchie Marylyn D, |
| [Effects of clopidogrel resistence and CYP2C19 genotype on the clinical prognosis of patients with acute coronary syndrome undergoing percutaneous coronary intervention]. Zhonghua xin xue guan bing za zhi 2020 9 48 (9): 765-771. He C B, Li Q, Ye Y C, Zhao X L, Tu C C, Zeng |
| Bedside testing of CYP2C19 gene for treatment of patients with PCI with antiplatelet therapy. BMC cardiovascular disorders 2020 6 20 (1): 268. Al-Rubaish Abdullah M, Al-Muhanna Fahad A, Alshehri Abdullah M, Al-Mansori Mohammed A, Alali Rudaynah A, Khalil Rania M, Al Faraidy Khalid A, Cyrus Cyril, Sulieman Mohammed M, Vatte Chittibabu, Claassens Daniel M F, Ten Berg Jurriën M, Asselbergs Folkert W, Al-Ali Amein |
| Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention: The TAILOR-PCI Randomized Clinical Trial. JAMA 2020 08 324 (8): 761-771. Pereira Naveen L, Farkouh Michael E, So Derek, Lennon Ryan, Geller Nancy, Mathew Verghese, Bell Malcolm, Bae Jang-Ho, Jeong Myung Ho, Chavez Ivan, Gordon Paul, Abbott J Dawn, Cagin Charles, Baudhuin Linnea, Fu Yi-Ping, Goodman Shaun G, Hasan Ahmed, Iturriaga Erin, Lerman Amir, Sidhu Mandeep, Tanguay Jean-Francois, Wang Liewei, Weinshilboum Richard, Welsh Robert, Rosenberg Yves, Bailey Kent, Rihal Charanj |
| Efficacy of Clopidogrel for Prevention of Stroke Based on CYP2C19 Allele Status in the POINT Trial. Stroke 2020 6 51 (7): 2058-2065. Meschia James F, Walton Ronald L, Farrugia Luca P, Ross Owen A, Elm Jordan J, Farrant Mary, Meurer William J, Lindblad Anne S, Barsan William, Ching Marilou, Gentile Nina, Ross Michael, Nahab Fadi, Easton J Donald, Kim Anthony S, Zurita Karla G, Cucchiara Brett, Johnston S Claibor |
| Risk of major adverse cardiovascular events of CYP2C19 loss-of-function genotype guided prasugrel/ticagrelor vs clopidogrel therapy for acute coronary syndrome patients undergoing percutaneous coronary intervention: a meta-analysis. Platelets 2020 7 32 (5): 591-600. Biswas Mohitosh, Kali Most Sumaiya Khatun, Biswas Tapash Kumar, Ibrahim Baharud |
| Whole blood dynamic platelet aggregation counting and 1-year clinical outcomes in patients with coronary heart diseases treated with clopidogrel. Platelets 2020 9 32 (7): 968-974. Wan Huaibin, Han Weichao, Wu Zhihao, Lie Zhenbang, Li Daqiang, Su Shaoh |
- Page last reviewed:Feb 1, 2023
- Page last updated:Mar 28, 2023
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