HuGE Literature Finder
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Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PLoS biology 2022 2 20 (2): e3001547. Richardson Tom G, Leyden Genevieve M, Wang Qin, Bell Joshua A, Elsworth Benjamin, Davey Smith George, Holmes Michael |
| Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.
Nature communications 2022 1 13 (1): 143. Scholz Markus, Horn Katrin, Pott Janne, Gross Arnd, Kleber Marcus E, Delgado Graciela E, Mishra Pashupati Prasad, Kirsten Holger, Gieger Christian, Müller-Nurasyid Martina, Tönjes Anke, Kovacs Peter, Lehtimäki Terho, Raitakari Olli, Kähönen Mika, Gylling Helena, Baber Ronny, Isermann Berend, Stumvoll Michael, Loeffler Markus, März Winfried, Meitinger Thomas, Peters Annette, Thiery Joachim, Teupser Daniel, Ceglarek U |
| Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes. JAMA cardiology 2018 Oct 3 (10): 957-966. Lotta Luca A, Stewart Isobel D, Sharp Stephen J, Day Felix R, Burgess Stephen, Luan Jian'an, Bowker Nicholas, Cai Lina, Li Chen, Wittemans Laura B L, Kerrison Nicola D, Khaw Kay-Tee, McCarthy Mark I, O'Rahilly Stephen, Scott Robert A, Savage David B, Perry John R B, Langenberg Claudia, Wareham Nicholas |
| Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study. The international journal of neuropsychopharmacology 2018 Jul . Alghamdi Jahad, Matou-Nasri Sabine, Alghamdi Faisal, Alghamdi Saleh, Alfadhel Majid, Padmanabhan Sando |
| Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. JAMA 2016 Oct 316 (13): 1383-1391. Lotta Luca A, Sharp Stephen J, Burgess Stephen, Perry John R B, Stewart Isobel D, Willems Sara M, Luan Jian'an, Ardanaz Eva, Arriola Larraitz, Balkau Beverley, Boeing Heiner, Deloukas Panos, Forouhi Nita G, Franks Paul W, Grioni Sara, Kaaks Rudolf, Key Timothy J, Navarro Carmen, Nilsson Peter M, Overvad Kim, Palli Domenico, Panico Salvatore, Quirós Jose-Ramón, Riboli Elio, Rolandsson Olov, Sacerdote Carlotta, Salamanca-Fernandez Elena, Slimani Nadia, Spijkerman Annemieke M W, Tjonneland Anne, Tumino Rosario, van der A Daphne L, van der Schouw Yvonne T, McCarthy Mark I, Barroso Inês, O'Rahilly Stephen, Savage David B, Sattar Naveed, Langenberg Claudia, Scott Robert A, Wareham Nicholas |
| Coding-sequence variants are associated with blood lipid levels in 14,473 Chinese. Human molecular genetics 2016 Aug . Lu Xiangfeng, Li Jun, Li Huaixing, Chen Yang, Wang Laiyuan, He Meian, Wang Yiqin, Sun Liang, Hu Yao, Huang Jianfeng, Wang Feijie, Liu Xuezhen, Chen Shufeng, Yu Kuai, Yang Xueli, Mo Zengnan, Lin Xu, Wu Tangchun, Gu Dongfe |
| Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits. Methods in molecular biology (Clifton, N.J.) 2015 1253 35-45. Ma Li, Keinan Alon, Clark Andrew |
| A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China. Lipids in health and disease 2014 13 147. Cha Erdenbat, Fu Zhen-Yan, Ma Yi-Tong, Zhu Qing, Xie Xiang, Liu F |
| Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations. PLoS genetics 2012 8 (5): e1002714. Ma Li, Brautbar Ariel, Boerwinkle Eric, Sing Charles F, Clark Andrew G, Keinan Al |
| Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy. DNA and cell biology 2010 Oct 29 (10): 629-37. Poduri Aruna, Khullar Madhu, Bahl Ajay, Sehrawat B S, Sharma Yashpaul, Talwar Kewal |
| A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians. DNA and cell biology 2009 Sep 28 (9): 451-60. Poduri Aruna, Khullar Madhu, Bahl Ajay, Sharma Yash Paul, Talwar Kewal |
| Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes. Pharmacogenetics and genomics 2008 Dec 18 (12): 1051-7. Knouff Christopher W, Lim Noha, Song Kijoung, Yuan Xin, Walker Max C, Townsend Ray, Waeber Gerard, Matthews Paul M, Vollenweider Peter, Waterworth Dawn M, Mooser Vince |
| LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism. The Journal of nutrition 2007 Sep 137 (9): 2062-7. Pocathikorn Anothai, Taylor Roger R, James Ian, Mamotte Cyril D |
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- Page last updated:Aug 16, 2022
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