HuGE Literature Finder
Records 1-30
|
Early-onset colorectal cancer: A distinct entity with unique genetic features.
Oncology letters 2020 Oct 20 (4): 33. Jiang Dan, Shu Chang, Lei Chuanfen, Wan Ying, Sun Linyo |
|
KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report.
Translational oncology 2020 Sep 13 (12): 100874. Luo Qianxin, Chen Dianke, Fan Xinjuan, Fu Xinhui, Ma Tenghui, Chen Dai |
|
Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial.
European journal of cancer (Oxford, England : 1990) 2020 Aug 137 250-259. Stahler Arndt, Stintzing Sebastian, von Einem Jobst C, Westphalen Christoph B, Heinrich Kathrin, Krämer Nicole, Michl Marlies, Modest Dominik P, von Weikersthal Ludwig Fischer, Decker Thomas, Kiani Alexander, Heintges Tobias, Kahl Christoph, Kullmann Frank, Scheithauer Werner, Moehler Markus, Kaiser Florian, Kirchner Thomas, Jung Andreas, Heinemann Volk |
|
Characterization of Chilean patients with sporadic colorectal cancer according to the three main carcinogenic pathways: Microsatellite instability, CpG island methylator phenotype and Chromosomal instability.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Jul 42 (7): 1010428320938492. Wielandt Ana María, Hurtado Claudia, Moreno C Mauricio, Villarroel Cynthia, Castro Magdalena, Estay Marlene, Simian Daniela, Martinez Maripaz, Vial Maria Teresa, Kronberg Udo, López-Köstner Francis |
|
Prognostic value of molecular biomarkers in patients with metastatic colorectal cancer: a real-world study.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Jun . García-Alfonso P, García-González G, Gallego I, Peligros M I, Ortega L, Torres Pérez-Solero G, Sandoval C, Muñoz Martin A, Blanco Codesido M, Calvo Ferrándiz A, Martin |
|
Colorectal carcinomas with mucinous differentiation are associated with high frequent mutation of KRAS or BRAF mutations, irrespective of quantity of mucinous component.
BMC cancer 2020 May 20 (1): 400. Li Xiaodong, Sun Katherine, Liao Xiaoyan, Gao Haijuan, Zhu Hongfa, Xu Rulia |
|
Targeted next generation sequencing of MLH1-deficient, MLH1 promoter hypermethylated and BRAF/RAS-wild-type colorectal adenocarcinomas is effective in detecting tumors with actionable oncogenic gene fusions.
Genes, chromosomes & cancer 2020 May . VaNková Bohuslava, VanEcek Tomáš, Ptáková Nikola, Hájková Veronika, Dušek Martin, Michal Michael, Švajdler Peter, Daum OndRej, Daumová Magdaléna, Michal Michal, Mezencev Roman, Švajdler Mari |
|
Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.
Translational oncology 2020 May 13 (7): 100786. Taniguchi Hiroya, Uehara Keisuke, Nakayama Goro, Nakayama Hiroshi, Aiba Toshisada, Hattori Norifumi, Kataoka Masato, Nakano Yasuyuki, Kawase Yoshihisa, Okochi Osamu, Matsuoka Hiroshi, Utsunomiya Setsuo, Sakamoto Eiji, Mori Yoshinori, Umeda Shinichi, Shikano Toshio, Komori Koji, Tajika Masahiro, Kadowaki Shigenori, Muro Kei, Yatabe Yasus |
|
Association Between Baseline Circulating Tumor Cells, Molecular Tumor Profiling, and Clinical Characteristics in a Large Cohort of Chemo-naïve Metastatic Colorectal Cancer Patients Prospectively Collected.
Clinical colorectal cancer 2020 Mar . Sastre Javier, Orden Virginia de la, Martínez Antonio, Bando Inmaculada, Balbín Milagros, Bellosillo Beatriz, Palanca Sarai, Peligros Gomez Maria Isabel, Mediero Beatriz, Llovet Patricia, Moral Virginia Moreno, Viéitez José Maria, García-Alfonso Pilar, Calle Silvia Gil, Ortiz-Morales Maria José, Salud Antonieta, Quintero Guillermo, Lopez Carlos, Díaz-Rubio Eduardo, Aranda Enrique, |
|
High mutational concordance between primary colorectal tumors and associated pulmonary metastases.
Journal of surgical oncology 2020 Feb . Corsini Erin M, Datar Saumil S, Mitchell Kyle G, Zhou Nicolas, Hofstetter Wayne L, Mehran Reza J, Rajaram Ravi, Rice David C, Roth Jack A, Sepesi Boris, Swisher Stephen G, Vaporciyan Ara A, Walsh Garrett L, Blackmon Shanda H, Loree Jonathan M, Morris Van K, Antonoff Mara |
|
Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients.
BMC cancer 2020 Jan 20 (1): 72. Manoharan Vahinipriya, Karunanayake Eric Hamilton, Tennekoon Kamani Hemamala, De Silva Sumadee, Imthikab Ahamed Ilyas Ahamed, De Silva Kanishka, Angunawela Preethika, Vishwakula Sameera, Lunec Jo |
|
Gene mutation profiling in Chinese colorectal cancer patients and its association with clinicopathological characteristics and prognosis.
Cancer medicine 2019 Nov . Ye Zu-Lu, Qiu Miao-Zhen, Tang Tao, Wang Fang, Zhou Yi-Xin, Lei Meng-Jie, Guan Wen-Long, He Cai-Y |
|
Fecal Genetic Mutations and Human DNA in Colorectal Cancer and Polyps Patients.
Asian Pacific journal of cancer prevention : APJCP 2019 Oct 20 (10): 2929-2934. Lima Jacqueline, Teixeira Yolanda, Pimenta Célia, Felipe Aledson Vitor, Silva Tiago Donizetti, Junior Ermelindo Ermelindo Della Libera, Saad Sarhan Sydney, Deak Elisabeth, Murray Helena, Manoukian Forones No |
|
Mutation profiling of cancer drivers in Brazilian colorectal cancer.
Scientific reports 2019 Sep 9 (1): 13687. Dos Santos Wellington, Sobanski Thais, de Carvalho Ana Carolina, Evangelista Adriane Feijó, Matsushita Marcus, Berardinelli Gustavo Nóriz, de Oliveira Marco Antonio, Reis Rui Manuel, Guimarães Denise Peixo |
|
Analytical and clinical validation of a novel amplicon-based NGS assay for the evaluation of circulating tumor DNA in metastatic colorectal cancer patients.
Clinical chemistry and laboratory medicine 2019 Jul . Wang Beili, Wu Shengchao, Huang Fei, Shen Minna, Jiang Huiqin, Yu Yiyi, Yu Qian, Yang Yihui, Zhao Ying, Zhou Yiwen, Pan Baishen, Liu Tianshu, Guo W |
|
Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer.
BMC cancer 2019 Jun 19 (1): 644. Cavagnari Mariana Abe Vicente, Silva Tiago Donizetti, Pereira Marco Antonio Haddad, Sauer Luísa Jacques, Shigueoka David, Saad Sarhan Sydney, Barão Katia, Ribeiro Carla Caroline Dias, Forones Nora Manouki |
|
[Combined detection of KRAS, NRAS, BRAF and PIK3CA mutations in the plasma and tumor tissues of colorectal cancer patients].
Zhonghua bing li xue za zhi = Chinese journal of pathology 2019 May 48 (5): 373-377. Liu X N, Tian Z, Wei X F, Wang Q, Zhang J X, Jin M S, Duan X |
|
Phase II study of high-sensitivity genotyping of KRAS, NRAS, BRAF and PIK3CA to ultra-select metastatic colorectal cancer patients for panitumumab plus FOLFIRI: the ULTRA trial.
Annals of oncology : official journal of the European Society for Medical Oncology 2019 May 30 (5): 796-803. Santos C, Azuara D, Viéitez J M, Páez D, Falcó E, Élez E, López-López C, Valladares M, Robles-Díaz L, García-Alfonso P, Bugés C, Durán G, Salud A, Navarro V, Capellá G, Aranda E, Salazar |
|
Calcium intake and colon cancer risk subtypes by tumor molecular characteristics.
Cancer causes & control : CCC 2019 Apr . Keum NaNa, Liu Li, Hamada Tsuyoshi, Qian Zhi Rong, Nowak Jonathan A, Cao Yin, da Silva Annacarolina, Kosumi Keisuke, Song Mingyang, Nevo Daniel, Wang Molin, Chan Andrew T, Meyerhardt Jeffrey A, Fuchs Charles S, Wu Kana, Ogino Shuji, Nishihara Reiko, Zhang Xueho |
|
Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer.
Journal of translational medicine 2019 Apr 17 (1): 137. Isnaldi Edoardo, Garuti Anna, Cirmena Gabriella, Scabini Stefano, Rimini Edoardo, Ferrando Lorenzo, Lia Michela, Murialdo Roberto, Tixi Lucia, Carminati Enrico, Panaro Andrea, Gallo Maurizio, Grillo Federica, Mastracci Luca, Repetto Lazzaro, Fiocca Roberto, Romairone Emanuele, Zoppoli Gabriele, Ballestrero Alber |
|
RNA sequencing reveals PNN and KCNQ1OT1as predictive biomarkers of clinical outcome in stage III colorectal cancer patients treated with adjuvant chemotherapy.
International journal of cancer 2019 Apr . Mini Enrico, Lapucci Andrea, Perrone Gabriele, D'Aurizio Romina, Napoli Cristina, Brugia Marco, Landini Ida, Tassi Renato, Picariello Lucia, Simi Lisa, Mancini Irene, Messerini Luca, Magi Alberto, Pinzani Pamela, Mazzei Teresita, Tonelli Francesco, Nobili Stefan |
|
Clinicopathological and molecular differences in colorectal cancer according to location.
The International journal of biological markers 2019 Mar 1724600818807164. Hsu Yu-Lun, Lin Chun-Chi, Jiang Jeng-Kai, Lin Hung-Hsin, Lan Yuan-Tzu, Wang Huann-Sheng, Yang Shung-Haur, Chen Wei-Shone, Lin Tzu-Chen, Lin Jen-Kou, Lin Pei-Ching, Chang Shih-Chi |
|
Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy.
BMC cancer 2019 Mar 19 (1): 255. Harada Kazuaki, Okamoto Wataru, Mimaki Sachiyo, Kawamoto Yasuyuki, Bando Hideaki, Yamashita Riu, Yuki Satoshi, Yoshino Takayuki, Komatsu Yoshito, Ohtsu Atsushi, Sakamoto Naoya, Tsuchihara Katsu |
|
Phase II study of high-sensitivity genotyping of KRAS, NRAS, BRAF and PIK3CA to ultra-select metastatic colorectal cancer patients for panitumumab plus FOLFIRI: the ULTRA trial.
Annals of oncology : official journal of the European Society for Medical Oncology 2019 Mar . Santos C, Azuara D, Viéitez J M, Páez D, Falcó E, Élez E, López-López C, Valladares M, Robles-Díaz L, García-Alfonso P, Bugés C, Durán G, Salud A, Navarro V, Capellá G, Salazar R, Aranda |
|
Ultra-selection of metastatic colorectal cancer patients using Next Generation Sequencing to improve clinical efficacy of anti-EGFR therapy.
Annals of oncology : official journal of the European Society for Medical Oncology 2019 Jan . Vidal J, Bellosillo B, Santos Vivas C, García-Alfonso P, Carrato A, Cano M T, García-Carbonero R, Élez E, Losa F, Massutí B, Valladares-Ayerbes M, Viéitez J M, Manzano J L, Gallego J, Pairet S, Capellá G, Salazar R, Tabernero J, Aranda E, Montagut |
|
High Frequency of KRAS Codon 146 and FBXW7 Mutations in Thai Patients with Stage II-III Colon Cancer.
Asian Pacific journal of cancer prevention : APJCP 2019 08 20 (8): 2319-2326. Korphaisarn Krittiya, Pongpaibul Ananya, Roothumnong Ekkapong, Pongsuktavorn Khontawan, Thamlikitkul Lucksamon, Anekpuritanang Tauangtham, Poungvarin Naravat, Thongnoppakhun Wanna, Pithukpakorn Man |
|
Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Journal of clinical pathology 2019 03 72 (3): 263-264. Susanti Susanti, Fadhil Wakkas, Murtaza Shamayal, Hassall James C, Ebili Henry O, Oniscu Anca, Ilyas Mohamm |
|
Prevalence and prognostic role of PIK3CA E545K mutation in Iranian colorectal cancer patients.
Gastroenterology and hepatology from bed to bench 2019 12 (Suppl1): S22-S29. Ranjbar Reza, Mohammadpour Somayeh, Torshizi Esfahani Amir, Namazian Sina, Yaghob-Taleghani Mohammad, Baghaei Kaveh, Mortazavi Tabatabaei Seyed Abdolreza, Pasharavesh Leila, Nazemalhosseini-Mojarad Ehs |
|
Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2018 Aug . Wojas-Krawczyk Kamila, Kalinka-Warzocha Ewa, Reszka Katarzyna, Nico? Marcin, Szumi?o Justyna, Ma?dziuk S?awomir, Szczepaniak Katarzyna, Kupnicka Dorota, Lewandowski Remigiusz, Milanowski Janusz, Krawczyk Paw |
|
Phase II Trial of Biweekly Cetuximab and Irinotecan as Third-Line Therapy for Pretreated KRAS Exon 2 Wild-Type Colorectal Cancer.
Cancer science 2018 Jun . Osumi Hiroki, Shinozaki Eiji, Mashima Tetsuo, Wakatsuki Takeru, Suenaga Mitsukuni, Ichimura Takashi, Ogura Mariko, Ota Yumiko, Nakayama Izuma, Takahari Daisuke, Chin Keisho, Miki Yoshio, Yamaguchi Kens |
|
The landscape of somatic mutation in sporadic Chinese colorectal cancer.
Oncotarget 2018 Jun 9 (44): 27412-27422. Liu Zhe, Yang Chao, Li Xiangchun, Luo Wen, Roy Bhaskar, Xiong Teng, Zhang Xiuqing, Yang Huanming, Wang Jian, Ye Zhenhao, Chen Yang, Song Jinghe, Ma Shuai, Zhou Yong, Yang Min, Fang Xiaodong, Du J |
|
Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Journal of the National Cancer Institute 2018 Apr . Loree Jonathan M, Bailey Ann M, Johnson Amber M, Yu Yao, Wu Wenhui, Bristow Christopher A, Davis Jennifer S, Shaw Kenna R, Broaddus Russell, Banks Kimberly C, Lanman Richard B, Meric-Bernstam Funda, Overman Michael J, Kopetz Scott, Raghav Kanw |
|
Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.
Scientific reports 2018 Apr 8 (1): 6076. Guo Fang, Gong Hai, Zhao Huanhuan, Chen Jing, Zhang Yiming, Zhang Lihua, Shi Xin, Zhang Aifeng, Jin Hui, Zhang Jianqiong, He You |
|
Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Virchows Archiv : an international journal of pathology 2018 Apr . Wang Yajian, Liu Haijing, Hou Yingyong, Zhou Xiaoyan, Liang Li, Zhang Zhihong, Shi Huaiyin, Xu Sanpeng, Hu Peizhen, Zheng Zuyu, Liu Rui, Tang Tingdong, Ye Feng, Liang Zhiyong, Bu Ho |
|
The Molecular Landscape of Synchronous Colorectal Cancer Reveals Genetic Heterogeneity.
Carcinogenesis 2018 Mar . Wang Xiangfeng, Fang Hu, Cheng Yong, Li Lin, Sun Xiaohui, Fu Tao, Huang Peide, Zhang Anping, Feng Zhimin, Li Chunxue, Huang Xuanlin, Li Guangyan, Du Peina, Yang Huanming, Fang Xiaodong, Li Fan, Gao Qiang, Liu Baoh |
|
Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.
Acta oncologica (Stockholm, Sweden) 2018 Jan 1-6. Christensen Troels Dreier, Palshof Jesper Andreas, Larsen Finn Ole, Poulsen Tim Svenstrup, Høgdall Estrid, Pfeiffer Per, Jensen Benny Vittrup, Yilmaz Mette Karen, Nielsen Dor |
|
Mutations of key driver genes in colorectal cancer progression and metastasis.
Cancer metastasis reviews 2018 Jan . Huang Dongdong, Sun Wenjie, Zhou Yuwei, Li Peiwei, Chen Fang, Chen Hanwen, Xia Dajing, Xu Enping, Lai Maode, Wu Yihua, Zhang Hong |
|
Clinical Impact and Prognostic Role of KRAS/BRAF/PIK3CA Mutations in Stage I Colorectal Cancer.
Disease markers 2018 2018 2959801. Reggiani Bonetti Luca, Barresi Valeria, Maiorana Antonino, Manfredini Samantha, Caprera Cecilia, Bettelli Stefan |
|
Racial Disparities in the Molecular Landscape of Cancer.
Anticancer research 2018 04 38 (4): 2235-2240. Heath Elisabeth I, Lynce Filipa, Xiu Joanne, Ellerbrock Angela, Reddy Sandeep K, Obeid Elias, Liu Stephen V, Bollig-Fischer Aliccia, Separovic Duska, Vanderwalde A |
|
Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Molecular carcinogenesis 2017 Dec . Sugai Tamotsu, Takahashi Yayoi, Eizuka Makoto, Sugimoto Ryo, Fujita Yasuko, Habano Wataru, Otsuka Kouki, Sasaki Akira, Yamamoto Eiichiro, Matsumoto Takayuki, Suzuki Hiro |
|
Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Oncotarget 2017 Nov 8 (55): 93567-93579. Shimada Yoshifumi, Kameyama Hitoshi, Nagahashi Masayuki, Ichikawa Hiroshi, Muneoka Yusuke, Yagi Ryoma, Tajima Yosuke, Okamura Takuma, Nakano Masato, Sakata Jun, Kobayashi Takashi, Nogami Hitoshi, Maruyama Satoshi, Takii Yasumasa, Hayashida Tetsu, Takaishi Hiromasa, Kitagawa Yuko, Oki Eiji, Konishi Tsuyoshi, Ishida Fumio, Kudo Shin-Ei, Ring Jennifer E, Protopopov Alexei, Lyle Stephen, Ling Yiwei, Okuda Shujiro, Ishikawa Takashi, Akazawa Kohei, Takabe Kazuaki, Wakai Toshifu |
|
Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer.
BMC gastroenterology 2017 Nov 17 (1): 121. Kim Dalyong, Kim Sun Young, Lee Ji Sung, Hong Yong Sang, Kim Jeong Eun, Kim Kyu-Pyo, Kim Jihun, Jang Se Jin, Yoon Young-Kwang, Kim Tae W |
|
Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Clinical colorectal cancer 2017 Oct . Chiu Joanne W, Krzyzanowska Monika K, Serra Stefano, Knox Jennifer J, Dhani Neesha C, Mackay Helen, Hedley David, Moore Malcolm, Liu Geoffrey, Burkes Ronald L, Brezden-Masley Christine, Roehrl Michael H, Craddock Kenneth J, Tsao Ming-Sound, Zhang Tong, Yu Celeste, Kamel-Reid Suzanne, Siu Lillian L, Bedard Philippe L, Chen Eric |
|
Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN.
Oncotarget 2017 Oct 8 (48): 84426-84433. Laes Jean-François, Sauvage Sebastien, Ghitti Grego |
|
Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer.
Oncotarget 2017 Sep 8 (42): 72352-72362. Chang Pi-Yueh, Chen Jinn-Shiun, Chang Shih-Cheng, Wang Mei-Chia, Chang Nai-Chung, Wen Ying-Hao, Tsai Wen-Sy, Liu Wei-Hsiu, Liu Hsiu-Ling, Lu Jang-J |
|
EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Sep 39 (9): 1010428317724517. Alvarez Karin, Orellana Paulina, Villarroel Cynthia, Contreras Luis, Kawachi Hiroshi, Kobayashi Maki, Wielandt Ana Maria, De la Fuente Marjorie, Triviño Juan Carlos, Kronberg Udo, Carvallo Pilar, López-Köstner Francis |
|
Tumor heterogeneity predicts metastatic potential in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep . Joung Je-Gun, Oh Bo Young, Hong Hye Kyung, AlKhalidi Hisham, Al-Alem Faisal, Lee Hae-Ock, Bae Joon Seol, Kim Jinho, Cha Hong-Ui, Alotaibi Maram, Cho Yong Beom, Hassanain Mazen, Lee Woo Yong, Park Woong-Ya |
|
Investigation of correlation between mutational status in key EGFR signaling genes and prognosis of stage II colorectal cancer.
Future oncology (London, England) 2017 Jul . Li Li, Ni Bei-Bei, Zhong Qing-Hua, Liu Yan-Hui, Zhang Ming-Hui, Zhang Ke-Ping, Chen Dai-Ci, Wang L |
|
Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
International journal of molecular sciences 2017 Jul 18 (7): . Chang Chu-Cheng, Lin Pei-Ching, Lin Chun-Chi, Lan Yuan-Tzu, Lin Hung-Hsin, Lin Chien-Hsing, Yang Shung-Haur, Liang Wen-Yi, Chen Wei-Shone, Jiang Jeng-Kai, Lin Jen-Kou, Chang Shih-Chi |
|
Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Molecular oncology 2017 Jun . Dienstmann Rodrigo, Elez Elena, Argiles Guillem, Matos Ignacio, Sanz-Garcia Enrique, Ortiz Carolina, Macarulla Teresa, Capdevila Jaume, Alsina Maria, Sauri Tamara, Verdaguer Helena, Vilaro Marta, Ruiz-Pace Fiorella, Viaplana Cristina, Garcia Ariadna, Landolfi Stefania, Palmer Hector G, Nuciforo Paolo, Rodon Jordi, Vivancos Ana, Tabernero Jos |
|
Genomic Profiling of Small-Bowel Adenocarcinoma.
JAMA oncology 2017 Jun . Schrock Alexa B, Devoe Craig E, McWilliams Robert, Sun James, Aparicio Thomas, Stephens Philip J, Ross Jeffrey S, Wilson Richard, Miller Vincent A, Ali Siraj M, Overman Michael |
|
Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
British journal of cancer 2017 Jun 117 (1): 136-143. Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaet |
|
Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Cancer 2017 May . Lee Dae-Won, Han Sae-Won, Cha Yongjun, Bae Jeong Mo, Kim Hwang-Phill, Lyu Jaemyun, Han Hyojun, Kim Hyoki, Jang Hoon, Bang Duhee, Huh Iksoo, Park Taesung, Won Jae-Kyung, Jeong Seung-Yong, Park Kyu Joo, Kang Gyeong Hoon, Kim Tae-Y |
|
Risk factors for brain metastases in patients with metastatic colorectal cancer.
Acta oncologica (Stockholm, Sweden) 2017 May 56 (5): 639-645. Christensen Troels Dreier, Palshof Jesper Andreas, Larsen Finn Ole, Høgdall Estrid, Poulsen Tim Svenstrup, Pfeiffer Per, Jensen Benny Vittrup, Yilmaz Mette Karen, Christensen Ib Jarle, Nielsen Dor |
|
APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases.
Annals of surgery 2017 Apr . Yamashita Suguru, Chun Yun-Shin, Kopetz Scott E, Maru Dipen, Conrad Claudius, Aloia Thomas A, Vauthey Jean-Nicol |
|
FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.
Oncotarget 2017 Apr . Korphaisarn Krittiya, Karlyle Morris Van, Overman Michael J, Fogelman David R, Kee Bryan K, Pratap Singh Raghav Kanwal, Manuel Shanequa, Shureiqi Imad, Wolff Robert A, Eng Cathy, Menter David, Hamilton Stanley R, Kopetz Scott, Dasari Arvi |
|
PIK3CA mutations contribute to acquired cetuximab resistance in metastatic colorectal cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Apr . Xu Jian Ming, Wang Yan, Wang You-Liang, Wang Yan, Liu Tao, Ni Ming, Li Man-Sheng, Lin Li, Ge Fei-Jiao, Gong Chun, Gu Jun-Yan, Jia Ru, Wang He-Fei, Chen Yu Ling, Liu Rong-Rui, Zhao Chuan-Hua, Tan Zhao-Li, Jin Yang, Zhu Yunping, Ogino Shuji, Qian Zhi Ro |
|
Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar 39 (3): 1010428317692246. Kleist Britta, Meurer Thuja, Poetsch Micae |
|
EGFR gene copy number predicts response to anti-EGFR treatment in RAS wild type and RAS/BRAF/PIK3CA wild type metastatic colorectal cancer.
International journal of cancer 2017 Feb 140 (4): 922-929. Ålgars Annika, Sundström Jari, Lintunen Minnamaija, Jokilehto Terhi, Kytölä Soili, Kaare Milja, Vainionpää Reetta, Orpana Arto, Österlund Pia, Ristimäki Ari, Carpen Olli, Ristamäki Rai |
|
Molecular profiling of metastatic colorectal tumors using next-generation sequencing: A single-institution experience.
Oncotarget 2017 Feb . Gong Jun, Cho May, Sy Marvin, Salgia Ravi, Fakih Marw |
|
Molecular Testing for Gastrointestinal Cancer.
Journal of pathology and translational medicine 2017 Feb . Lee Hye Seung, Kim Woo Ho, Kwak Yoonjin, Koh Jiwon, Bae Jeong Mo, Kim Kyoung-Mee, Chang Mee Soo, Han Hye Seung, Kim Joon Mee, Kim Hwal Woong, Chang Hee Kyung, Choi Young Hee, Park Ji Y, Gu Mi Jin, Lhee Min Jin, Kim Jung Yeon, Kim Hee Sung, Cho Mee-Yon, , |
|
Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Feb 39 (2): 1010428317692265. Jauhri Mayank, Bhatnagar Akanksha, Gupta Satish, Bp Manasa, Minhas Sachin, Shokeen Yogender, Aggarwal Shy |
|
Feasibility of multiplexed gene mutation detection in plasma samples of colorectal cancer patients by mass spectrometric genotyping.
PloS one 2017 12 (5): e0176340. Shin Su-Jin, Chun Sung-Min, Kim Tae-Im, Kim Yu Jin, Choi Hyun-Jeung, Jang Se Jin, Kim Jih |
|
Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
BMC cancer 2017 01 17 (1): 38. Nakayama Izuma, Shinozaki Eiji, Matsushima Tomohiro, Wakatsuki Takeru, Ogura Mariko, Ichimura Takashi, Ozaka Masato, Takahari Daisuke, Suenaga Mitsukuni, Chin Keisho, Mizunuma Nobuyuki, Yamaguchi Kens |
|
Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Journal of gastrointestinal oncology 2016 Dec 7 (6): 882-902. Al-Shamsi Humaid O, Jones Jeremy, Fahmawi Yazan, Dahbour Ibrahim, Tabash Aziz, Abdel-Wahab Reham, Abousamra Ahmed O S, Shaw Kenna R, Xiao Lianchun, Hassan Manal M, Kipp Benjamin R, Kopetz Scott, Soliman Amr S, McWilliams Robert R, Wolff Robert |
|
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Dec . Shia Jinru, Schultz Nikolaus, Kuk Deborah, Vakiani Efsevia, Middha Sumit, Segal Neil H, Hechtman Jaclyn F, Berger Michael F, Stadler Zsofia K, Weiser Martin R, Wolchok Jedd D, Boland C Richard, Gönen Mithat, Klimstra David |
|
Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Oncotarget 2016 Dec . Ashktorab Hassan, Mokarram Pooneh, Azimi Hamed, Olumi Hasti, Varma Sudhir, Nickerson Michael L, Brim Hass |
|
[A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2016 Nov 43 (12): 1800-1802. Yagi Ryoma, Shimada Yoshifumi, Miura Kohei, Tajima Yosuke, Okamura Takuma, Nakano Masato, Ichikawa Hiroshi, Nagahashi Masayuki, Sakata Jun, Kobayashi Takashi, Kameyama Hitoshi, Wakai Toshifumi, Nogami Hitoshi, Maruyama Satoshi, Takii Yasuma |
|
Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer.
Oncotarget 2016 Nov . Tury Sandrine, Becette Véronique, Assayag Franck, Vacher Sophie, Benoist Camille, Kamal Maud, Marangoni Elisabetta, Bièche Ivan, Lerebours Florence, Callens Céli |
|
Mutation location on the RAS oncogene effects pathologic features and survival after resection of colorectal liver metastases.
Cancer 2016 Oct . Frankel Timothy L, Vakiani Efsevia, Nathan Hari, DeMatteo Ronald P, Kingham T Peter, Allen Peter J, Jarnagin William R, Kemeny Nancy E, Solit David B, D'Angelica Michael |
|
Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Molecular cancer 2016 Oct 15 (1): 63. Kovaleva Valentina, Geissler Anna-Lena, Lutz Lisa, Fritsch Ralph, Makowiec Frank, Wiesemann Sebastian, Hopt Ulrich T, Passlick Bernward, Werner Martin, Lassmann Sil |
|
Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
The oncologist 2016 Sep . Rankin Andrew, Klempner Samuel J, Erlich Rachel, Sun James X, Grothey Axel, Fakih Marwan, George Thomas J, Lee Jeeyun, Ross Jeffrey S, Stephens Philip J, Miller Vincent A, Ali Siraj M, Schrock Alexa |
|
Comparison of the molecular profile of brain metastases from colorectal cancer and corresponding primary tumors.
Future oncology (London, England) 2016 Aug . Aprile Giuseppe, Casagrande Mariaelena, De Maglio Giovanna, Fontanella Caterina, Rihawi Karim, Bonotto Marta, Pisa Federica E, Tuniz Francesco, Pizzolitto Stefano, Fasola Gianpie |
|
Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
World journal of gastroenterology 2016 Aug 22 (30): 6944-54. Lo Nigro Cristiana, Ricci Vincenzo, Vivenza Daniela, Granetto Cristina, Fabozzi Teresa, Miraglio Emanuela, Merlano Marco |
|
Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival.
Oncotarget 2016 Aug 7 (34): 55098-55109. Mima Kosuke, Nowak Jonathan A, Qian Zhi Rong, Cao Yin, Song Mingyang, Masugi Yohei, Shi Yan, da Silva Annacarolina, Gu Mancang, Li Wanwan, Hamada Tsuyoshi, Zhang Xuehong, Wu Kana, Meyerhardt Jeffrey A, Baba Hideo, Giovannucci Edward L, Chan Andrew T, Fuchs Charles S, Ogino Shuji, Nishihara Rei |
|
Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.
Virchows Archiv : an international journal of pathology 2016 Jul . Grellety Thomas, Gros Audrey, Pedeutour Florence, Merlio Jean-Philippe, Duranton-Tanneur Valerie, Italiano Antoine, Soubeyran Isabel |
|
Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Medical oncology (Northwood, London, England) 2016 Jul 33 (7): 71. Li Zhe-Zhen, Bai Long, Wang Feng, Zhang Zi-Chen, Wang Fang, Zeng Zhao-Lei, Zeng Jun-Bo, Zhang Dong-Sheng, Wang Feng-Hua, Wang Zhi-Qiang, Li Yu-Hong, Shao Jian-Yong, Xu Rui-H |
|
CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
International journal of clinical oncology 2016 Jul . Zhang Xiaofei, Shimodaira Hideki, Soeda Hiroshi, Komine Keigo, Takahashi Hidekazu, Ouchi Kota, Inoue Masahiro, Takahashi Masanobu, Takahashi Shin, Ishioka Chikas |
|
Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.
Cancer research and treatment : official journal of Korean Cancer Association 2016 Jul . Kim Kyu-Pyo, Kim Jeong-Eun, Hong Yong Sang, Ahn Sung-Min, Chun Sung Min, Hong Seung-Mo, Jang Se Jin, Yu Chang Sik, Kim Jin Cheon, Kim Tae W |
|
Prognostic role of tumor PIK3CAmutation in colorectal cancer: a systematic review and meta-analysis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2016 Jul . Mei Z, Duan C, Li C, Cui L, Ogino |
|
Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors with 2 or More Somatic Mutations in Mismatch Repair Genes.
Gastroenterology 2016 Jun . Cohen Stacey A, Turner Emily H, Beightol Mallory B, Jacobson Angela, Gooley Ted A, Salipante Stephen J, Haraldsdottir Sigurdis, Smith Christina, Scroggins Sheena, Tait Jonathan F, Grady William M, Lin Edward H, Cohn David E, Goodfellow Paul J, Arnold Mark W, de la Chapelle Albert, Pearlman Rachel, Hampel Heather, Pritchard Colin |
|
Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma - occurence and prognostic significance.
Oncotarget 2016 Jun . Módos Orsolya, Reis Henning, Niedworok Christian, Rübben Herbert, Szendröi Attila, Szász Marcell A, Tímár József, Baghy Kornélia, Kovalszky Ilona, Golabek Tomasz, Chlosta Piotr, Okon Krzysztof, Peyronnet Benoit, Mathieu Romain, Shariat Shahrokh F, Hollósi Péter, Nyirády Péter, Szarvas Tib |
|
Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.
Gut 2016 May . Masugi Yohei, Nishihara Reiko, Yang Juhong, Mima Kosuke, da Silva Annacarolina, Shi Yan, Inamura Kentaro, Cao Yin, Song Mingyang, Nowak Jonathan A, Liao Xiaoyun, Nosho Katsuhiko, Chan Andrew T, Giannakis Marios, Bass Adam J, Hodi F Stephen, Freeman Gordon J, Rodig Scott, Fuchs Charles S, Qian Zhi Rong, Ogino Shu |
|
Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response.
Oncotarget 2016 Apr . Li Zhe-Zhen, Wang Feng, Zhang Zi-Chen, Wang Fang, Zhao Qi, Zhang Dong-Sheng, Wang Feng-Hua, Wang Zhi-Qiang, Luo Hui-Yan, He Ming-Ming, Wang De-Shen, Jin Ying, Ren Chao, Qiu Miao-Zhen, Ren Jian, Pan Zhi-Zhong, Li Yu-Hong, Shao Jiao-Yong, Xu Rui-H |
|
A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma.
Clinical colorectal cancer 2016 Mar . Bowles Daniel W, Kochenderfer Mark, Cohn Allen, Sideris Lucas, Nguyen Nghia, Cline-Burkhardt Vivian, Schnadig Ian, Choi Minsig, Nabell Lisle, Chaudhry Arvind, Ruxer Robert, Ucar Antonio, Hausman Diana, Walker Luke, Spira Alexander, Jimeno Anton |
|
The Prognostic Influence of BRAF Mutation and other Molecular, Clinical and Laboratory Parameters in Stage IV Colorectal Cancer.
Pathology oncology research : POR 2016 Mar . Karadima Maria L, Saetta Angelica A, Chatziandreou Ilenia, Lazaris Andreas C, Patsouris Efstratios, Tsavaris Nikola |
|
Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial.
ESMO open 2016 1 (6): e000086. Martinelli E, Cardone C, Troiani T, Normanno N, Pisconti S, Sforza V, Bordonaro A R, Rachiglio A M, Lambiase M, Latiano T P, Modoni G, Cordio S, Giuliani F, Biglietto M, Montesarchio V, Barone C, Tonini G, Cinieri S, Febbraro A, Rizzi D, De Vita F, Orditura M, Colucci G, Maiello E, Ciardiello |
|
Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.
Journal of translational medicine 2016 14 (1): 118. Dallol Ashraf, Buhmeida Abdelbaset, Al-Ahwal Mahmoud Shaheen, Al-Maghrabi Jaudah, Bajouh Osama, Al-Khayyat Shadi, Alam Rania, Abusanad Atlal, Turki Rola, Elaimi Aisha, Alhadrami Hani A, Abuzenadah Mohammed, Banni Huda, Al-Qahtani Mohammed H, Abuzenadah Adel |
|
Comparison of KRAS and PIK3CA gene status between primary tumors and paired metastases in colorectal cancer.
OncoTargets and therapy 2016 9 2329-35. He Qiong, Xu Qi, Wu Wei, Chen Lei, Sun Weijing, Ying Jie |
|
Oncogene Mutations in Colorectal Polyps Identified in the Norwegian Colorectal Cancer Prevention (NORCCAP) Screening Study.
Clinical medicine insights. Pathology 2016 9 19-28. Lorentzen Jon A, Grzyb Krzysztof, De Angelis Paula M, Hoff Geir, Eide Tor J, Andresen Per Ar |
|
Prognostic impact of mutation profiling in patients with stage II and III colon cancer.
Scientific reports 2016 6 24310. Shen Yinchen, Han Xiaohong, Wang Jianfei, Wang Shuai, Yang Hongying, Lu Shih-Hsin, Shi Yuank |
|
Comparative genomic analysis of primary versus metastasis in colorectal carcinomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): 10500. Vakiani E, Janakiraman M, Shen R, Zeng Z, Cercek A, Kemeny N E, Heguy A, Paty P, Chan T A, Saltz L, Weiser M R, Solit D |
|
Heterogeneous prevalence of mutations in KRAS, BRAF, and PIK3CA genes among Sardinian patients with colorectal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): e14100. Palomba G, Colombino M, Contu A S, Massidda B, Baldino G, Ionta M T, Pazzola A, Capelli F, Trova V, Sedda T, Farris A, Tanda F, Budroni M, Palmieri G, Cossu A, |
|
High throughput sequencing technology (Sequenom) as a tool to detect SNPs in human metastatic colorectal cancer (mCRC) and cell lines.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): e14083. Nayak J B, Maitra R, Basu-Mallick A, Sood A, Mariadason J, Reynolds D M, Goel |
|
The role of activating mutations of KRAS, BRAF, and PIK3CA pathway convergence at the transcriptional level and prediction of treatment response to cetuximab in colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 May 29 (15_suppl): 3534. Simon I, Tian S, Moreno V, Roepman P, Tabernero J, Snel M, Macarulla T, Van't Veer L, Bernards R, Capella |
|
Impact of KRAS, BRAF, and PIK3CA mutations, PTEN, AREG, and EREG expression, and skin rash in metastatic colorectal cancer patients treated with cetuximab-containing salvage treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 445. Saridaki Z, Tzardi M, Papadaki C, Sfakianaki M, Pega F, Kalikaki A, Tsakalaki E, Mavroudis D, Georgoulias V, Sougklakos |
|
Phase II trial of cetuximab plus irinotecan for FOLFOX and FOLFIRI-refractory patients with EGFR-positive advanced and/or metastatic colorectal cancer: Evaluation of the efficacy and safety based on KRAS mutation status (T- CORE0801).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 573. Shimodaira H, Soeda H, Gamoh M, Andoh H, Yamaguchi T, Watanabe M, Isobe H, Sudo T, Kato S, Ishioka C, |
|
Prospective study of genetic mutations in matched tumor and plasma specimens in colorectal cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 356. Perkins G, Dukes J, Yap T A, Riisnaes R, Pope L, Cassidy A, Denholm K A, Gonzalez de Castro D, Chau I, De Bono J |
|
The role of KRAS, BRAF, NRAS, and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 May 27 (15_suppl): 4020. Lambrechts D, De Roock W, Prenen H, De Schutter J, Jacobs B, Biesmans B, Claes B, De Hertogh G, Van Cutsem E, Tejpar |
|
Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution.
Annals of Saudi medicine 0 38 (4): 251-259. Ibrahim Tony, Saer-Ghorra Claude, Trak-Smayra Vivane, Nadiri Samah, Yazbeck Charbel, Baz Maria, Kattan Joseph |
- Page last reviewed:Oct 1, 2020
- Page last updated:Oct 21, 2020
- Content source: