Human Genome Epidemiology Literature Finder
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Records 1 - 30 (of 36 Records) |
| Query Trace: Colorectal Neoplasms and MTOR[original query] |
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| Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations. Molecular cancer therapeutics 2013 Dec 12 (12): 2857-63. Ganesan Prasanth, Janku Filip, Naing Aung, Hong David S, Tsimberidou Apostolia M, Falchook Gerald S, Wheler Jennifer J, Piha-Paul Sarina A, Fu Siqing, Stepanek Vanda M, Lee J Jack, Luthra Rajyalakshmi, Overman Michael J, Kopetz E Scott, Wolff Robert A, Kurzrock Razel |
| Genetic variations in STK11, PRKAA1, and TSC1 associated with prognosis for patients with colorectal cancer. Annals of surgical oncology 2014 Dec 21 Suppl 4 S634-9. Lee Soo Jung, Kang Byung Woog, Chae Yee Soo, Kim Hye Jin, Park Su Yeon, Park Jun Seok, Choi Gyu Seog, Jeon Hyo-Sung, Lee Won Kee, Kim Jong Gwa |
| FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors. PloS one 2014 9 (2): e89388. Jardim Denis L, Wheler Jennifer J, Hess Kenneth, Tsimberidou Apostolia M, Zinner Ralph, Janku Filip, Subbiah Vivek, Naing Aung, Piha-Paul Sarina A, Westin Shannon N, Roy-Chowdhuri Sinchita, Meric-Bernstam Funda, Hong David |
| The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis. Acta oncologica (Stockholm, Sweden) 2014 Jul 53 (7): 852-64. Therkildsen Christina, Bergmann Troels K, Henrichsen-Schnack Tine, Ladelund Steen, Nilbert M |
| Functional promoter rs2295080 T>G variant in MTOR gene is associated with risk of colorectal cancer in a Chinese population. Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2015 Mar 70 28-32. Xu Ming, Gao Yan, Yu Tingting, Wang Jirong, Cheng Liang, Cheng Lifang, Cheng Dawei, Zhu Bao |
| Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer. Investigational new drugs 2015 Jun 33 (3): 720-8. Do Khanh, Speranza Giovanna, Bishop Rachel, Khin Sonny, Rubinstein Larry, Kinders Robert J, Datiles Manuel, Eugeni Michelle, Lam Michael H, Doyle L Austin, Doroshow James H, Kummar Shivaa |
| PI3K/Akt/mTOR Signaling and Plasma Membrane Proteins Are Implicated in Responsiveness to Adjuvant Dendritic Cell Vaccination for Metastatic Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Jul . Qian David C, Xiao Xiangjun, Byun Jinyoung, Suriawinata Arief A, Her Stephanie, Amos Christopher I, Barth Richa |
| Clinical manifestations and STK11 germline mutations in Taiwanese patients with Peutz-Jeghers syndrome. Asian journal of surgery 2017 9 41 (5): 480-485. Chiang Jy-Ming, Chen Tse-Chi |
| Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival. Annals of surgical oncology 2017 9 24 (13): 4051-4058. Clarke Callisia N, Lee Michael S, Wei Wei, Manyam Ganiraju, Jiang Zhi-Qin, Lu Yiling, Morris Jeffrey, Broom Bradley, Menter David, Vilar-Sanchez Eduardo, Raghav Kanwal, Eng Cathy, Chang George J, Simon Iris, Bernards Rene, Overman Michael, Mills Gordon B, Maru Dipen, Kopetz Sco |
| Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. British journal of cancer 2017 Jun 117 (1): 136-143. Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaet |
| Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN. Oncotarget 2017 Oct 8 (48): 84426-84433. Laes Jean-François, Sauvage Sebastien, Ghitti Grego |
| Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study. Current oncology (Toronto, Ont.) 2017 1 23 (6): e571-e575. Sheffield B S, Tessier-Cloutier B, Li-Chang H, Shen Y, Pleasance E, Kasaian K, Li Y, Jones S J M, Lim H J, Renouf D J, Huntsman D G, Yip S, Laskin J, Marra M, Schaeffer D |
| [Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations]. Zhonghua bing li xue za zhi = Chinese journal of pathology 2018 Jul 47 (7): 492-498. Yu L, Liu Z Y, Jiao J, Shi X L, Cui W L, Zhang W, Li Q |
| Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3. Cancer 2018 Jan . Ross Jeffrey S, Fakih Marwan, Ali Siraj M, Elvin Julia A, Schrock Alexa B, Suh James, Vergilio Jo-Anne, Ramkissoon Shakti, Severson Eric, Daniel Sugganth, Fabrizio David, Frampton Garrett, Sun James, Miller Vincent A, Stephens Philip J, Gay Laurie |
| Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer. World journal of gastroenterology 2019 2 25 (7): 808-823. Wan Xiang-Bin, Wang Ai-Qin, Cao Jian, Dong Zhi-Chuang, Li Ning, Yang Sen, Sun Miao-Miao, Li Zhi, Luo Su-X |
| Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC). Journal of medical genetics 2019 2 56 (6): 370-379. Lo Winifred, Zhu Bin, Sabesan Arvind, Wu Ho-Hsiang, Powers Astin, Sorber Rebecca A, Ravichandran Sarangan, Chen Ina, McDuffie Lucas A, Quadri Humair S, Beane Joal D, Calzone Kathleen, Miettinen Markku M, Hewitt Stephen M, Koh Christopher, Heller Theo, Wacholder Sholom, Rudloff U |
| Targeted next generation sequencing of MLH1-deficient, MLH1 promoter hypermethylated, and BRAF/RAS-wild-type colorectal adenocarcinomas is effective in detecting tumors with actionable oncogenic gene fusions. Genes, chromosomes & cancer 2020 May . Va?ková Bohuslava, Van??ek Tomáš, Ptáková Nikola, Hájková Veronika, Dušek Martin, Michal Michael, Švajdler Peter, Daum Ond?ej, Daumová Magdaléna, Michal Michal, Mezencev Roman, Švajdler Mari |
| Genomic variation as a marker of response to neoadjuvant therapy in locally advanced rectal cancer. Molecular & cellular oncology 2020 7 (3): 1716618. Douglas Jason K, Callahan Rose E, Hothem Zachary A, Cousineau Craig S, Kawak Samer, Thibodeau Bryan J, Bergeron Shelli, Li Wei, Peeples Claire E, Wasvary Harry |
| PIK3CA mutations in plasma circulating tumor DNA predict survival and treatment outcomes in patients with advanced cancers. ESMO open 2021 9 6 (5): 100230. Dumbrava E E, Call S G, Huang H J, Stuckett A L, Madwani K, Adat A, Hong D S, Piha-Paul S A, Subbiah V, Karp D D, Fu S, Naing A, Tsimberidou A M, Moulder S L, Koenig K H, Barcenas C H, Kee B K, Fogelman D R, Kopetz E S, Meric-Bernstam F, Janku |
| Phosphorylated mTOR expression as a predictor of survival after liver resection for colorectal liver metastases. Journal of surgical oncology 2021 Jun . Konishi Takanori, Yoshidome Hiroyuki, Shida Takashi, Furukawa Katsunori, Takayashiki Tsukasa, Kuboki Satoshi, Takano Shigetsugu, Miyazaki Masaru, Ohtsuka Masayu |
| A Low Tumor Mutational Burden and PTEN Mutations Are Predictors of a Negative Response to PD-1 Blockade in MSI-H/dMMR Gastrointestinal Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 2021 4 27 (13): 3714-3724. Chida Keigo, Kawazoe Akihito, Kawazu Masahito, Suzuki Toshihiro, Nakamura Yoshiaki, Nakatsura Tetsuya, Kuwata Takeshi, Ueno Toshihide, Kuboki Yasutoshi, Kotani Daisuke, Kojima Takashi, Taniguchi Hiroya, Mano Hiroyuki, Ikeda Masafumi, Shitara Kohei, Endo Itaru, Yoshino Takayu |
| Clinical-grade whole-genome sequencing and 3' transcriptome analysis of colorectal cancer patients. Genome medicine 2021 2 13 (1): 33. Stodolna Agata, He Miao, Vasipalli Mahesh, Kingsbury Zoya, Becq Jennifer, Stockton Joanne D, Dilworth Mark P, James Jonathan, Sillo Toju, Blakeway Daniel, Ward Stephen T, Ismail Tariq, Ross Mark T, Beggs Andrew |
| Tumour mutational burden predicts resistance to EGFR/BRAF blockade in BRAF-mutated microsatellite stable metastatic colorectal cancer. European journal of cancer (Oxford, England : 1990) 2021 12 161 90-98. Randon Giovanni, Intini Rossana, Cremolini Chiara, Elez Elena, Overman Michael J, Lee Jeeyun, Manca Paolo, Bergamo Francesca, Pagani Filippo, Antista Maria, Angerilli Valentina, Ros Montaña Francisco Javier, Lavacchi Daniele, Boccaccino Alessandra, Fucà Giovanni, Brich Silvia, Cattaneo Laura, Fassan Matteo, Pietrantonio Filippo, Lonardi Sa |
| Impact of AKT1 polymorphism on DNA damage, BTG2 expression, and risk of colorectal cancer development. Radiology and oncology 2022 Aug 56 (3): 336-345. Zubair Hina, Khan Zahid, Imran Muhamm |
| Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer. BMC cancer 2022 7 22 (1): 818. Wang Chenxing, Aikemu Batuer, Shao Yanfei, Zhang Sen, Yang Guang, Hong Hiju, Huang Ling, Jia Hongtao, Yang Xiao, Zheng Minhua, Sun Jing, Li Jianw |
| Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study. BioData mining 2022 1 15 (1): 2. Simons Colinda C J M, Schouten Leo J, Godschalk Roger W L, van Schooten Frederik-Jan, Stoll Monika, Van Steen Kristel, van den Brandt Piet A, Weijenberg Matty |
| Relationship Between MUC4 Variants and Metastatic Recurrence in Colorectal Cancer. International journal of general medicine 2023 11 16 5077-5087. Jieqiong Liu, Rongge Xing, Jiakang Shao, Shunchang Ji |
| Fusobacterium Nucleatum-Induced Tumor Mutation Burden Predicts Poor Survival of Gastric Cancer Patients. Cancers 2023 1 15 (1): . Hsieh Yung-Yu, Kuo Wen-Lin, Hsu Wan-Ting, Tung Shui-Yi, Li Ch |
| Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer. Science advances 2024 5 10 (22): eadk3121. David A Drew, Andre E Kim, Yi Lin, Conghui Qu, John Morrison, Juan Pablo Lewinger, Eric Kawaguchi, Jun Wang, Yubo Fu, Natalia Zemlianskaia, Virginia Díez-Obrero, Stephanie A Bien, Niki Dimou, Demetrius Albanes, James W Baurley, Anna H Wu, Daniel D Buchanan, John D Potter, Ross L Prentice, Sophia Harlid, Volker Arndt, Elizabeth L Barry, Sonja I Berndt, Emmanouil Bouras, Hermann Brenner, Arif Budiarto, Andrea Burnett-Hartman, Peter T Campbell, Robert Carreras-Torres, Graham Casey, Jenny Chang-Claude, David V Conti, Matthew A M Devall, Jane C Figueiredo, Stephen B Gruber, Andrea Gsur, Marc J Gunter, Tabitha A Harrison, Akihisa Hidaka, Michael Hoffmeister, Jeroen R Huyghe, Mark A Jenkins, Kristina M Jordahl, Anshul Kundaje, Loic Le Marchand, Li Li, Brigid M Lynch, Neil Murphy, Rami Nassir, Polly A Newcomb, Christina C Newton, Mireia Obón-Santacana, Shuji Ogino, Jennifer Ose, Rish K Pai, Julie R Palmer, Nikos Papadimitriou, Bens Pardamean, Andrew J Pellatt, Anita R Peoples, Elizabeth A Platz, Gad Rennert, Edward Ruiz-Narvaez, Lori C Sakoda, Peter C Scacheri, Stephanie L Schmit, Robert E Schoen, Mariana C Stern, Yu-Ru Su, Duncan C Thomas, Yu Tian, Konstantinos K Tsilidis, Cornelia M Ulrich, Caroline Y Um, Fränzel J B van Duijnhoven, Bethany Van Guelpen, Emily White, Li Hsu, Victor Moreno, Ulrike Peters, Andrew T Chan, W James Gauderm |
| Multigene Panel Next-Generation Sequencing Techniques in the Management of Patients with Metastatic Colorectal Carcinoma: The Way Forward for Personalized Treatment? A Single-Center Experience. International journal of molecular sciences 2024 10 25 (20): . Laura Matteucci, Francesco Giulio Sullo, Chiara Gallio, Luca Esposito, Margherita Muratore, Ilario Giovanni Rapposelli, Daniele Calistri, Elisabetta Petracci, Claudia Rengucci, Laura Capelli, Elisa Chiadini, Paola Ulivi, Alessandro Passardi, Alessandro Bitto |
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