HuGE Literature Finder
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Records 1-100
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Clustering of ABCB1 and CYP2C19 Genetic Variants Predicts Risk of Major Bleeding and Thrombotic Events in Elderly Patients with Acute Coronary Syndrome Receiving Dual Antiplatelet Therapy with Aspirin and Clopidogrel.
Drugs & aging 2018 Jun . Galeazzi Roberta, Olivieri Fabiola, Spazzafumo Liana, Rose Giuseppina, Montesanto Alberto, Giovagnetti Simona, Cecchini Sara, Malatesta Gelsomina, Di Pillo Raffaele, Antonicelli Rober |
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CYP2C19 and ABCB1 genetic polymorphisms correlate with the recurrence of ischemic cardiovascular adverse events after clopidogrel treatment.
Journal of clinical laboratory analysis 2018 Jun 32 (5): e22369. Hou Xumin, Han Wenzheng, Gan Qian, Liu Yuan, Fang Wei |
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Clopidogrel Pharmacogenetics in Iranian Patients Undergoing Percutaneous Coronary Intervention.
Cardiovascular toxicology 2018 May . Mahdieh Nejat, Rabbani Ahmad, Firouzi Ata, Zahedmehr Ali, Hoseinimoghaddam Maryam, Saeidi Sedigheh, Sanati Hamidreza, Basiri Hosseinali, Noohi Feridoun, Rabbani Bahareh, Maleki Maj |
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Association between multidrug resistance-1 C3435T gene polymorphism and right ventricular dysfunction in patients with chronic obstructive pulmonary disease: cross-sectional study.
Sao Paulo medical journal = Revista paulista de medicina 2018 Mar 136 (2): 140-143. Yücel O?uzhan, Güne? Hakan, Yücel Hasan, Zorlu A |
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Multidrug resistance 1 (MDR1/ABCB1) gene polymorphism (rs1045642 C?>?T) and susceptibility to multiple myeloma: a systematic review and meta-analysis.
Hematology (Amsterdam, Netherlands) 2018 Mar 1-7. Razi Bahman, Anani Sarab Gholamreza, Omidkhoda Azadeh, Alizadeh Shah |
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Bleeding predictors in patients following venous thromboembolism treated with vitamin K antagonists: Association with increased number of single nucleotide polymorphisms.
Vascular pharmacology 2018 Feb . Bryk Agata Hanna, Wypasek Ewa, Plens Krzysztof, Awsiuk Magdalena, Undas Anet |
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Effect of cilostazol on platelet reactivity among patients with peripheral artery disease on clopidogrel therapy.
Drug metabolism and personalized therapy 2018 Feb . Hernandez-Suarez Dagmar F, Núñez-Medina Hector, Scott Stuart A, Lopez-Candales Angel, Wiley Jose M, Garcia Mario J, Melin Kyle, Nieves-Borrero Karid, Rodriguez-Ruiz Christina, Marshall Lorraine, Duconge Jor |
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Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation.
British journal of clinical pharmacology 2018 Feb . Ueshima Satoshi, Hira Daiki, Kimura Yuuma, Fujii Ryo, Tomitsuka Chiho, Yamane Takuya, Tabuchi Yohei, Ozawa Tomoya, Itoh Hideki, Ohno Seiko, Horie Minoru, Terada Tomohiro, Katsura Toshi |
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Association between CYP2C19 and ABCB1 polymorphisms and clopidogrel resistance in clopidogrel-treated Chinese patients.
Anatolian journal of cardiology 2018 Jan . Zhuo Zhong Ling, Xian Hai Peng, Long Yan, Liu Chang, Sun Yuan Yuan, Ma Yin Ting, Gao Hua, Zhao Jing Zhong, Zhao Xiao T |
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[Association of ABCB1 gene polymorphisms with aspirin resistance in patients with ischemic stroke].
Zhonghua yi xue za zhi 2016 Dec 96 (47): 3819-3824. Wang Z Y, Wang Y, Sui A H, Dong |
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Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy.
Acta pharmacologica Sinica 2016 Sep . Peng Ling-Ling, Zhao Yuan-Qi, Zhou Zi-Yi, Jin Jing, Zhao Min, Chen Xin-Meng, Chen Ling-Yan, Cai Ye-Feng, Li Jia-Li, Huang M |
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OS 08-03 PHARMACOGENETIC MARKERS OF SURVIVAL.
Journal of hypertension 2016 Sep 34 Suppl 1 - ISH 2016 Abstract Book e68. Erdman Vera, Tuktarova Ilsia, Nasibullin Timur, Timasheva Ianina, Mustafina Ol |
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Results of genotype-guided antiplatelet therapy in patients who undergone percutaneous coronary intervention with stent.
International journal of cardiology 2016 Sep 225 289-295. Sánchez-Ramos Jesús, Dávila-Fajardo Cristina Lucía, Toledo Frías Pablo, Díaz Villamarín Xando, Martínez-González Luis Javier, Martínez Huertas Susana, Burillo Gómez Francisco, Caballero Borrego Juan, Bautista Pavés Alicia, Marín Guzmán Mª Carmen, Ramirez Hernández José Antonio, Correa Vilches Concepción, Cabeza Barrera Jo |
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The impact of CYP4F2, ABCB1, and GGCX polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation.
Drug metabolism and personalized therapy 2016 Sep 31 (3): 173-8. Sychev Dmitriy Alexeyevich, Rozhkov Aleksandr Vladimirovich, Kazakov Ruslan Evgenyevich, Ananichuk Anna Viktorov |
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Genetic polymorphisms influence on the response to clopidogrel in peripheral artery disease patients following percutaneous transluminal angioplasty.
Pharmacogenomics 2016 Jul . Díaz-Villamarín Xando, Dávila-Fajardo Cristina Lucía, Martínez-González Luis Javier, Carmona-Sáez Pedro, Sánchez-Ramos Jesús, Álvarez Cubero María Jesús, Salmerón-Febres Luis Miguel, Cabeza Barrera Jose, Fernández-Quesada Fid |
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Effect of genetic and coexisting polymorphisms on platelet response to clopidogrel in Chinese Han patients with acute coronary syndrome.
Journal of genetics 2016 Jun 95 (2): 231-7. Liu Xu, Luo Yu, Lai Yan, Yao Yian, Li Jimin, Wang Yunkai, Zheng S Lilly, Xu Jianfeng, Liu Xue |
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Relationship between genetic polymorphisms of drug efflux transporter MDR1 (ABCB1) and response to losartan in hypertension patients.
European review for medical and pharmacological sciences 2016 Jun 20 (11): 2460-7. Gökta? M T, Pepedil F, Karaca Ö, Kalk???m S, Cevik L, Gumus E, Guven G S, Babaoglu M O, Bozkurt A, Yasar |
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Pharmacogenetics of dabigatran etexilate interindividual variability.
Thrombosis research 2016 May 144 1-5. Dimatteo Claudia, D'Andrea Giovanna, Vecchione Gennaro, Paoletti Oriana, Cappucci Filomena, Tiscia Giovanni Luca, Buono Matteo, Grandone Elvira, Testa Sophie, Margaglione Mauriz |
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[Relationship between ATP-binding cassette subfamily B member 1 and cytochrome P450 2C19 polymorphisms and the effect of clopidogrel post percutaneous coronary intervention in patients with acute coronary syndrome].
Zhonghua xin xue guan bing za zhi 2016 Apr 44 (4): 309-14. Zhou C F, Ren Y H, Song Y Q, Yi J, Han B S, Xue Q, Fu Z H, Li D |
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Association of MDR1 single-nucleotide polymorphisms and haplotype variants with multiple myeloma in Chinese Jiangsu Han population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan . Yin Guangli, Xiao Zhengrui, Ni Ying, Qu Xiaoyan, Wu Hanxin, Lu Hua, Qian Sixuan, Chen Lijuan, Li Jianyong, Qiu Hairong, Miao Kouro |
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Genetic and Nongenetic Factors Affecting Clopidogrel Response in the Egyptian Population.
Clinical and translational science 2016 Jan . Khalil B M, Shahin M H, Solayman Mhm, Langaee T, Schaalan M F, Gong Y, Hammad L N, Al-Mesallamy H O, Hamdy N M, El-Hammady W A, Johnson J |
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Effects of TNF?, NOS3, MDR1 Gene Polymorphisms on Clinical Parameters, Prognosis and Survival of Multiple Myeloma Cases.
Asian Pacific journal of cancer prevention : APJCP 2016 17 (3): 1009-14. Basmaci C, Pehlivan M, Tomatir Ag, Sever T, Okan V, Yilmaz M, Oguzkan-Balci S, Pehlivan |
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P-Glycoprotein Polymorphism C3435T Is Associated with Dose-Adjusted Clopidogrel and 2-Oxo-Clopidogrel Concentration.
Pharmacology 2015 Dec 97 (3-4): 101-106. Stokanovic Dragana, Nikolic Valentina N, Konstantinovic Sandra S, Zvezdanovic Jelena B, Lilic Jelena, Apostolovic Svetlana R, Pavlovic Milan, Zivkovic Vladimir S, Jevtovic-Stoimenov Tatjana, Jankovic Slobodan |
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ABCB1 gene variants, digoxin and risk of sudden cardiac death in a general population.
Heart (British Cardiac Society) 2015 Nov . Niemeijer Maartje N, van den Berg Marten E, Deckers Jaap W, Aarnoudse Adrianus L H J, Hofman Albert, Franco Oscar H, Uitterlinden André G, Rijnbeek Peter R, Eijgelsheim Mark, Stricker Bruno |
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A prospective randomized evaluation of a pharmacogenomic approach to antiplatelet therapy among patients with ST-elevation myocardial infarction: the RAPID STEMI study.
The pharmacogenomics journal 2015 Apr . So D Y F, Wells G A, McPherson R, Labinaz M, Le May M R, Glover C, Dick A J, Froeschl M, Marquis J-F, Gollob M H, Tran L, Bernick J, Hibbert B, Roberts J |
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Genetic polymorphisms of CYP2C19 2 and ABCB1 C3435T affect the pharmacokinetic and pharmacodynamic responses to clopidogrel in 401 patients with acute coronary syndrome.
Gene 2015 Mar 558 (2): 200-7. Wang Xia-Qin, Shen Chen-Lin, Wang Bang-Ning, Huang Xiao-Hui, Hu Zhang-le, Li J |
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ABCB1 hypomethylation is associated with decreased antiplatelet effects of clopidogrel in Chinese ischemic stroke patients.
Die Pharmazie 2015 Feb 70 (2): 97-102. Yang Jie, Zhou Jun-Shan, Zhao Yan-Xia, Yang Zheng-Hua, Zhao Hong-Dong, Zhang Ying-Dong, Zou Jian-J |
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Polymorphisms of CYP2C9, VKORC1, MDR1, APOE and UGT1A1 genes and the therapeutic warfarin dose in Brazilian patients with thrombosis: a prospective cohort study.
Molecular diagnosis & therapy 2014 Dec 18 (6): 675-83. de Oliveira Almeida Vanessa Cristina, Ribeiro Daniel Dias, Gomes Karina Braga, Godard Ana Lúcia Brunial |
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Relationship between ABCB1 polymorphisms, thromboelastography and risk of bleeding events in clopidogrel-treated patients with ST-elevation myocardial infarction.
Thrombosis research 2014 Nov 134 (5): 970-5. Zhang Jia-Hui, Tang Xiao-Fang, Zhang Yin, Wang Jing, Yao Yi, Ma Yuan-Liang, Xu Bo, Gao Run-Lin, Gao Zhan, Chen Jue, Song Lei, Wu Yuan, Meng Xian-Min, Yuan Jin-Qi |
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Use of a simplified nomogram to individualize digoxin dosing versus standard dosing practices in patients with heart failure.
Pharmacotherapy 2014 Nov 34 (11): 1121-31. DiDomenico Robert J, Bress Adam P, Na-Thalang Kwanta, Tsao Yvonne Y, Groo Vicki L, Deyo Kelly L, Patel Shitalben R, Bishop Jeffrey R, Bauman Jerry |
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Maternal medication use, fetal 3435 C>T polymorphism of the ABCB1 gene, and risk of isolated septal defects in a Han Chinese population.
Pediatric cardiology 2014 Oct 35 (7): 1132-41. Wang Chuan, Zhou Kaiyu, Xie Liang, Li Yifei, Zhan Yalan, Qiao Lina, Qin Chaoyi, Liu Ruiqi, Hua Yim |
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MDR1 C3435T polymorphism associated with the development of clinical features in Behçet's disease in Iranian Azeri Turkish patients.
International journal of dermatology 2014 Oct 53 (10): 1235-40. Bonyadi Mortaza, Gholizadeh Monireh, Soltan-Ali Mahbo |
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Prediction of stable acenocoumarol dose by a pharmacogenetic algorithm.
Pharmacogenetics and genomics 2014 Oct 24 (10): 501-13. Jiménez-Varo Enrique, Cañadas-Garre Marisa, Gutiérrez-Pimentel María J, Calleja-Hernández Miguel |
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ABCB1 C3435T polymorphism and the risk of ischemic heart disease: a meta-analysis.
Genetic testing and molecular biomarkers 2014 Sep 18 (9): 636-45. Wang Qi, Jin Yuan-Zhe, Zhou Shao-Bo, Wang Li-Jie, Lei Ming-Ming, Wang Yong, Miao C |
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Pharmacogenetics role in the safety of acenocoumarol therapy.
Thrombosis and haemostasis 2014 Sep 112 (3): 522-36. Jiménez-Varo E, Cañadas-Garre M, Henriques C I, Pinheiro A M, Gutiérrez-Pimentel M J, Calleja-Hernández M |
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The effects of CES1A2 A(-816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease.
Pharmacogenetics and genomics 2014 Apr 24 (4): 204-10. Xie Cheng, Ding Xiaoliang, Gao Jie, Wang Haipeng, Hang Yongfu, Zhang Hua, Zhang Jingjing, Jiang Bin, Miao Liy |
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ABCB1 C3435T polymorphism and the risk of coronary heart disease: a meta-analysis.
Genetic testing and molecular biomarkers 2014 Mar 18 (3): 164-73. Jin Yuanzhe, Wang Qi, Wang Guofeng, Zhang Xueying, Yan Bin, Hu Wei |
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ABCB1 polymorphism and gender affect the pharmacokinetics of amlodipine in Chinese patients with essential hypertension: a population analysis.
Drug metabolism and pharmacokinetics 2014 29 (4): 305-11. Zuo Xiao-cong, Zhang Wen-li, Yuan Hong, Barrett Jeffrey S, Hua Ye, Huang Zhi-jun, Zhou Hong-hao, Pei Qi, Guo Cheng-xian, Wang Jiang-lin, Yang Guo-pi |
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Development of a multiplex and cost-effective genotype test toward more personalized medicine for the antiplatelet drug clopidogrel.
International journal of molecular sciences 2014 15 (5): 7699-710. Jeong Hye-Eun, Lee Su-Jun, Cha Eun-Young, Kim Eun-Young, Kim Ho-Sook, Song Young Hwan, Shin Jae-Go |
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Interplay between genetic and clinical variables affecting platelet reactivity and cardiac adverse events in patients undergoing percutaneous coronary intervention.
PloS one 2014 9 (7): e102701. Siller-Matula Jolanta M, Lang Irene M, Neunteufl Thomas, Kozinski Marek, Maurer Gerald, Linkowska Katarzyna, Grzybowski Tomasz, Kubica Jacek, Jilma Ber |
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A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.
American journal of hypertension 2013 Dec 26 (12): 1428-36. Liu Ming, Li Yan, Citterio Lorena, Huang Qi-Fang, Zeng Wei-Fang, Sheng Chang-Sheng, Wei Fang-Fei, Dong Qian, Li Ge-Le, Kang Yuan-Yuan, Zhang Lu, Xu Ting-Yan, Li Jing-Jing, Song Jie, Manunta Paolo, Wang Ji-Gua |
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Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways.
Thrombosis and haemostasis 2013 Dec 110 (6): 1223-31. Braun Oscar Ö, Angiolillo Dominick J, Ferreiro Jose L, Jakubowski Joseph A, Winters Kenneth J, Effron Mark B, Duvvuru Suman, Costigan Timothy M, Sundseth Scott, Walker Joseph R, Saucedo Jorge F, Kleiman Neal S, Varenhorst Christo |
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Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease.
JACC. Cardiovascular interventions 2013 Nov 6 (11): 11. Viviani Anselmi C, Briguori C, Roncarati R, Papa L, Visconti G, Focaccio A, De Micco F, Latronico MV, Pagnotta P, Condorelli G |
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C3435T polymorphism of MDR1 gene with warfarin resistance.
Clinica chimica acta; international journal of clinical chemistry 2013 Oct 425 34-6. Kim Yeongsic, Smith Andrew, Wu Alan H |
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The association of MDR1 C3435T and G2677T/A polymorphisms with plasma platelet-activating factor levels and coronary artery disease risk in Turkish population.
Gene 2013 Sep 527 (1): 301-5. Ayaz Gulsel, Batar Bahadir, Kanigur Gonul, Guven Mehmet, Onaran Ilhan, Karadag Bilgehan, Ilerigelen Baris, Dirican Ahmet, Ulutin Turg |
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Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction.
International journal of cardiology 2013 Sep 167 (6): 2882-8. Verschuren Jeffrey J W, Boden Helèn, Wessels Judith A M, van der Hoeven Bas L, Trompet Stella, Heijmans Bastiaan T, Putter Hein, Guchelaar Henk-Jan, Schalij Martin J, Jukema J Wout |
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Genetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients.
Thrombosis research 2013 Jul 132 (1): 81-7. Zhang Lanning, Chen Yanming, Jin Ying, Qu Fei, Li Jiayue, Ma Cong, Yang Jie, Xu Bin, Wang Hongjuan, Li Xiaoqi, Li Yang, Zhang Yuxiao, Lu Caiyi, Yin To |
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The impact of gene polymorphism and high on-treatment platelet reactivity on clinical follow-up: outcomes in patients with acute coronary syndrome after drug-eluting stent implantation.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2013 Jul 9 (3): 316-27. Liang Zhen-Yang, Han Ya-Ling, Zhang Xiao-Lin, Li Yi, Yan Cheng-Hui, Kang Ji |
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Mutational analysis clopidogrel resistance and platelet function in patients scheduled for coronary artery bypass grafting.
Genomics 2013 Jun 101 (6): 313-7. Correll Mick, Johnson Christopher K, Ferrari Giovanni, Brizzio Mariano, Mak Andrew W C, Quackenbush John, Shaw Richard E, Zapolanski Alex, Grau Juan |
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Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe.
Journal of ethnopharmacology 2013 Apr 146 (3): 744-9. Zhou Quan, Ye Zhen, Ruan Zourong, Zeng |
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Cardiovascular risk among patients on clopidogrel anti-platelet therapy after placement of drug-eluting stents is modified by genetic variants in both the CYP2C19 and ABCB1 genes.
Thrombosis and haemostasis 2013 Jan 109 (4): 4. Carlquist JF, Knight S, Horne BD, Huntinghouse JA, Rollo JS, Muhlestein JB, May H, Anderson JL |
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[Informativeness of genetic factors for optimization of personalized therapy with clopidogrel].
Kardiologiia 2013 53 (8): 72-5. Knauér N Iu, Lifshits G I, Voronina E N, Koleda N V, Gus'kova E |
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Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.
PloS one 2013 8 (10): e76984. McDonough Caitrin W, Gillis Nancy K, Alsultan Abdullah, Chang Shin-Wen, Kawaguchi-Suzuki Marina, Lang Jason E, Shahin Mohamed Hossam A, Buford Thomas W, El Rouby Nihal M, Sá Ana C C, Langaee Taimour Y, Gums John G, Chapman Arlene B, Cooper-DeHoff Rhonda M, Turner Stephen T, Gong Yan, Johnson Julie |
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Increased risk for congenital heart defects in children carrying the ABCB1 Gene C3435T polymorphism and maternal periconceptional toxicants exposure.
PloS one 2013 8 (7): e68807. Wang Chuan, Xie Liang, Zhou Kaiyu, Zhan Yalan, Li Yifei, Li Huaying, Qiao Lina, Wang Fang, Hua Yim |
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[Clopidogrel metabolism related gene polymorphisms in Chinese patients with acute coronary syndrome].
Zhonghua xin xue guan bing za zhi 2012 Nov 40 (11): 11. Feng GX, Liang Y, Bai Y, Chen T, Liu X, Yang YM, Wang XY, Yang YJ, Zhu J |
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Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke.
Human genetics 2012 Nov 131 (11): 1775-81. Munshi Anja |
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MDR-1 C3435T polymorphism may affect blood pressure in resistant hypertensive patients independently of its effects on aldosterone release.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2012 Nov . Lacchini R, Figueiredo VN, Demacq C, Coeli-Lacchini FB, Martins LC, Yugar-Toledo J, Coca A, Tanus-Santos JE, Moreno H |
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Near patient anti-platelet response testing over time and gene analysis in patients admitted with acute coronary syndromes.
Platelets 2012 Nov . Amoah V, Storey RF, Worrall AP, Goodridge K, Lovatt T, Smallwood A, Armesilla AL, Nevill AM, Cotton JM |
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Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.
European heart journal 2012 Sep 33 (17): 2151-62. Park Yongwhi, Jeong Young-Hoon, Tantry Udaya S, Ahn Jong Hwa, Kwon Tae Jung, Park Jeong Rang, Hwang Seok-Jae, Gho Eun-Ha, Bliden Kevin P, Kwak Choong Hwan, Hwang Jin-Yong, Kim Sunjoo, Gurbel Paul |
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MDR1 gene polymorphisms may be associated with Behçet's disease and its colchicum treatment response.
Gene 2012 Sep 505 (2): 333-9. Rustemoglu Aydin, Gül Ülker, Gümü?-Akay Güvem, Gönül Müzeyyen, Yi?it Serbülent, Bozkurt Nihan, Karada? Aynur, Pi?kin Emine, Sunguro?lu Asuman, Kad?k?ran Ahm |
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CYP2C19*2/ABCB1-C3435T polymorphism and risk of cardiovascular events in coronary artery disease patients on clopidogrel: Is clinical testing helpful?
Indian heart journal 2012 64 (4): 4. Singh M, Shah T, Adigopula S, Molnar J, Ahmed A, Khosla S, Arora R |
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Factors associated with the failure of clopidogrel dose-adjustment according to platelet reactivity monitoring to optimize P2Y12-ADP receptor blockade.
Thrombosis research 2012 Jul 130 (1): 70-4. Bonello Laurent, Camoin-Jau Laurence, Mancini Julien, Bessereau Jacques, Grosdidier Charlotte, Alessi Marie-Christine, Ostorero Michel, Dignat-George Françoise, Paganelli Fran |
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ABCB1 C3435T polymorphism and risk of adverse clinical events in clopidogrel treated patients: a meta-analysis.
Thrombosis research 2012 Jun 129 (6): 754-9. Luo Man, Li Jiaoxing, Xu Xiaowei, Sun Xunsha, Sheng Wen |
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Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and multiple myeloma risk: a case-control study in the context of the International Multiple Myeloma rESEarch (IMMEnSE) consortium.
Leukemia 2012 Jun 26 (6): 1419-22. Martino A, Campa D, Buda G, Sainz J, García-Sanz R, Jamroziak K, Reis R M, Weinhold N, Jurado M, Ríos R, Szemraj-Rogucka Z, Marques H, Szemraj J, Stein A, Kumar R, Orciuolo E, Gemignani F, Landi S, Goldschmidt H, Petrini M, Dumontet C, Canzian F, Rossi A |
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Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: the GIFT (Genotype Information and Functional Testing) study.
Journal of the American College of Cardiology 2012 May 59 (22): 1928-37. Price Matthew J, Murray Sarah S, Angiolillo Dominick J, Lillie Elizabeth, Smith Erin N, Tisch Rebecca L, Schork Nicholas J, Teirstein Paul S, Topol Eric J, |
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Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 May 30 (13): 1422-8. Visscher Henk, Ross Colin J D, Rassekh S Rod, Barhdadi Amina, Dubé Marie-Pierre, Al-Saloos Hesham, Sandor George S, Caron Huib N, van Dalen Elvira C, Kremer Leontien C, van der Pal Helena J, Brown Andrew M K, Rogers Paul C, Phillips Michael S, Rieder Michael J, Carleton Bruce C, Hayden Michael R, |
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Association of C3435T multi drug resistance gene-1 polymorphism with aspirin resistance in ischemic stroke and its subtypes.
Journal of the neurological sciences 2012 Apr 315 (1-2): 72-6. Sharma Vandana, Kaul Subhash, Al-Hazzani Amal, Prabha T Surya, Rao Polugari Prem Kumar Manohar, Dadheech Sneha, Jyothy A, Munshi Anja |
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CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention.
Thrombosis research 2012 Apr 129 (4): 441-6. Kassimis George, Davlouros Periklis, Xanthopoulou Ioanna, Stavrou Eleana F, Athanassiadou Aglaia, Alexopoulos Dimitri |
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Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers.
British journal of clinical pharmacology 2012 Apr 73 (4): 619-28. Jensen Berit Packert, Roberts Rebecca Lee, Vyas Ritva, Bonke Gitte, Jardine David L, Begg Evan Jam |
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No association of ABCB1 C3435T genotype with clopidogrel response or risk of stent thrombosis in patients undergoing coronary stenting.
Circulation. Cardiovascular interventions 2012 Feb 5 (1): 82-8, S1-2. Jaitner Juliane, Morath Tanja, Byrne Robert A, Braun Siegmund, Gebhard Daniela, Bernlochner Isabell, Schulz Stefanie, Mehilli Julinda, Schömig Albert, Koch Werner, Kastrati Adnan, Sibbing Di |
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ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta-analysis.
PloS one 2012 7 (10): e46366. Su Jia, Xu Jin, Li Xiaojing, Zhang Han, Hu Juwei, Fang Renyuan, Chen Xiaom |
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Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study.
PloS one 2012 7 (8): e42875. Boudou-Rouquette Pascaline, Narjoz Céline, Golmard Jean Louis, Thomas-Schoemann Audrey, Mir Olivier, Taieb Fabrice, Durand Jean-Philippe, Coriat Romain, Dauphin Alain, Vidal Michel, Tod Michel, Loriot Marie-Anne, Goldwasser François, Blanchet Beno |
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Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.
PloS one 2012 7 (6): e39178. Chen Dong-Yi, Wang Chao-Yung, Wen Ming-Shien, Lee Tsong-Hai, Chu Yen, Hsieh Ming-Jer, Chang Shang-Hung, Lee Cheng-Hung, Wang Jian-Liang, Chen Chun-Chi, Lu Laing-Suei, Lee Ming-Ta, Yeh San-Jou, Lin Fun-Chiung, Hsieh I-Cha |
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Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy.
American journal of cardiovascular drugs : drugs, devices, and other interventions 2011 Dec 11 (6): 401-9. Cai Jingjing, Huang Zhijun, Yang Guoping, Cheng Ke, Ye Qifa, Ming Yingzi, Zuo Xiaocong, Zhou Peipei, Yuan Ho |
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Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin.
Circulation. Cardiovascular interventions 2011 Dec 4 (6): 585-94. Jeong Young-Hoon, Tantry Udaya S, Kim In-Suk, Koh Jin-Sin, Kwon Tae Jung, Park Yongwhi, Hwang Seok-Jae, Bliden Kevin P, Kwak Choong Hwan, Hwang Jin-Yong, Gurbel Paul |
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Predicting Clopidogrel Response Using DNA Samples Linked to an Electronic Health Record.
Clinical pharmacology and therapeutics 2011 Dec . Delaney JT, Ramirez AH, Bowton E, Pulley JM, Basford MA, Schildcrout JS, Shi Y, Zink R, Oetjens M, Xu H, Cleator JH, Jahangir E, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC |
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Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction.
Clinical pharmacology and therapeutics 2011 Oct 90 (4): 561-7. Simon T, Steg P G, Becquemont L, Verstuyft C, Kotti S, Schiele F, Ferrari E, Drouet E, Grollier G, Danchin |
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Impact of genetic variants on post-clopidogrel platelet reactivity in patients after elective percutaneous coronary intervention.
Pharmacogenomics 2011 Sep 12 (9): 1269-80. Rideg Orsolya, Komócsi András, Magyarlaki Tamás, Tokés-Füzesi Margit, Miseta Attila, Kovács Gábor L, Aradi Dáni |
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Impact on response and survival of DNA repair single nucleotide polymorphisms in relapsed or refractory multiple myeloma patients treated with thalidomide.
Leukemia research 2011 Sep 35 (9): 1178-83. Cibeira María Teresa, de Larrea Carlos Fernández, Navarro Alfons, Díaz Tania, Fuster Dolors, Tovar Natalia, Rosiñol Laura, Monzó Mariano, Bladé Jo |
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Effect of ABCB1 genotype on pre- and post-cardiac transplantation plasma lipid concentrations.
Journal of cardiovascular translational research 2011 Jun 4 (3): 304-12. Taegtmeyer Anne B, Breen Jane B, Smith John, Rogers Paula, Kullak-Ublick Gerd A, Yacoub Magdi H, Banner Nicholas R, Barton Paul J |
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Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome.
Journal of the American College of Cardiology 2011 Jun 57 (25): 2474-83. Campo Gianluca, Parrinello Giovanni, Ferraresi Paolo, Lunghi Barbara, Tebaldi Matteo, Miccoli Matteo, Marchesini Jlenia, Bernardi Francesco, Ferrari Roberto, Valgimigli Mar |
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General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.
American journal of obstetrics and gynecology 2011 Mar 204 (3): 236.e1-8. Obermann-Borst Sylvia A, Isaacs Aaron, Younes Zobia, van Schaik Ron H N, van der Heiden Ilse P, van Duyn Cornelia M, Steegers Eric A P, Steegers-Theunissen Régine P |
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Impact of ABCB1 allelic variants on QTc interval prolongation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Feb 17 (4): 937-46. Sissung Tristan M, Gardner Erin R, Piekarz Richard L, Howden Reuben, Chen Xiaohong, Woo Sukyung, Franke Ryan, Clark James A, Miller-DeGraff Laura, Steinberg Seth M, Venzon David, Liewehr David, Kleeberger Steven R, Bates Susan E, Price Douglas K, Rosing Douglas R, Cabell Christopher, Sparreboom Alex, Figg William |
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[Factors determining clinical effectiveness of clopidogrel and prognosis of patients with stable ischemic heart disease].
Kardiologiia 2011 51 (2): 8-18. Komarov A L, Panchenko E P, Donnikov A E, Shakhmatova O O, Dzhalilova G V, Iliushchenko T |
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Investigation of ABCB1 gene polymorphism with colchicine response in Behçet's disease.
Genetics and molecular research : GMR 2011 10 (1): 1-6. Saricaoglu H, Yilmaz M, Karkucak M, Ozturk H Z Y, Yakut T, Gulten T, Baskan E B, Aydogan K, Dilek |
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Large-scale candidate gene analysis of HDL particle features.
PloS one 2011 6 (1): e14529. Kaess Bernhard M, Tomaszewski Maciej, Braund Peter S, Stark Klaus, Rafelt Suzanne, Fischer Marcus, Hardwick Robert, Nelson Christopher P, Debiec Radoslaw, Huber Fritz, Kremer Werner, Kalbitzer Hans Robert, Rose Lynda M, Chasman Daniel I, Hopewell Jemma, Clarke Robert, Burton Paul R, Tobin Martin D, Hengstenberg Christian, Samani Nilesh |
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Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis.
European journal of clinical pharmacology 2010 Nov 66 (11): 1119-30. Joy Melanie S, Boyette Tammy, Hu Yichun, Wang Jinzhao, La Mary, Hogan Susan L, Stewart Paul W, Falk Ronald J, Dooley Mary Anne, Smith Philip |
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Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.
Annals of hematology 2010 Nov 89 (11): 1133-40. Buda Gabriele, Ricci Deborah, Huang C Chris, Favis Reyna, Cohen Nadine, Zhuang Sen H, Harousseau Jean-Luc, Sonneveld Pieter, Bladé Joan, Orlowski Robert |
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Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.
DNA and cell biology 2010 Oct 29 (10): 629-37. Poduri Aruna, Khullar Madhu, Bahl Ajay, Sehrawat B S, Sharma Yashpaul, Talwar Kewal |
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Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.
Lancet (London, England) 2010 Oct 376 (9749): 1320-8. Wallentin Lars, James Stefan, Storey Robert F, Armstrong Martin, Barratt Bryan J, Horrow Jay, Husted Steen, Katus Hugo, Steg P Gabriel, Shah Svati H, Becker Richard C, |
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Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.
Lancet (London, England) 2010 Oct 376 (9749): 1312-9. Mega Jessica L, Close Sandra L, Wiviott Stephen D, Shen Lei, Walker Joseph R, Simon Tabassome, Antman Elliott M, Braunwald Eugene, Sabatine Marc |
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Protective effect of the CYP2C19 *17 polymorphism with increased activation of clopidogrel on cardiovascular events.
American heart journal 2010 Sep 160 (3): 506-12. Tiroch Klaus A, Sibbing Dirk, Koch Werner, Roosen-Runge Tobias, Mehilli Julinda, Schömig Albert, Kastrati Adn |
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Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction.
Pharmacogenomics 2010 Aug 11 (8): 1065-76. Peters Bas J M, Rodin Andrei S, Klungel Olaf H, van Duijn Cornelia M, Stricker Bruno H Ch, van't Slot Ruben, de Boer Anthonius, Maitland-van der Zee Anke-Hil |
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Blood pressure and hypertension are associated with 7 loci in the Japanese population.
Circulation 2010 Jun 121 (21): 2302-9. Takeuchi Fumihiko, Isono Masato, Katsuya Tomohiro, Yamamoto Ken, Yokota Mitsuhiro, Sugiyama Takao, Nabika Toru, Fujioka Akihiro, Ohnaka Keizo, Asano Hiroyuki, Yamori Yukio, Yamaguchi Shuhei, Kobayashi Shotai, Takayanagi Ryoichi, Ogihara Toshio, Kato Norihi |
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Besides CYP2C19*2, the variant allele CYP2C9*3 is associated with higher on-clopidogrel platelet reactivity in patients on dual antiplatelet therapy undergoing elective coronary stent implantation.
Pharmacogenetics and genomics 2010 Jan 20 (1): 18-25. Harmsze Ankie, van Werkum Jochem W, Bouman Heleen J, Ruven Henk J, Breet Nicolien J, Ten Berg Jurrien M, Hackeng Christian M, Tjoeng Mathieu M, Klungel Olaf H, de Boer Anthonius, Deneer Vera |
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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics 2009 Nov 85 (5): 628-42. Talmud Philippa J, Drenos Fotios, Shah Sonia, Shah Tina, Palmen Jutta, Verzilli Claudio, Gaunt Tom R, Pallas Jacky, Lovering Ruth, Li Kawah, Casas Juan Pablo, Sofat Reecha, Kumari Meena, Rodriguez Santiago, Johnson Toby, Newhouse Stephen J, Dominiczak Anna, Samani Nilesh J, Caulfield Mark, Sever Peter, Stanton Alice, Shields Denis C, Padmanabhan Sandosh, Melander Olle, Hastie Claire, Delles Christian, Ebrahim Shah, Marmot Michael G, Smith George Davey, Lawlor Debbie A, Munroe Patricia B, Day Ian N, Kivimaki Mika, Whittaker John, Humphries Steve E, Hingorani Aroon D, , , |
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A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians.
DNA and cell biology 2009 Sep 28 (9): 451-60. Poduri Aruna, Khullar Madhu, Bahl Ajay, Sharma Yash Paul, Talwar Kewal |
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Identification of genetic variants associated with response to statin therapy.
Arteriosclerosis, thrombosis, and vascular biology 2009 Sep 29 (9): 1310-5. Mega Jessica L, Morrow David A, Brown Alison, Cannon Christopher P, Sabatine Marc |
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ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma.
Leukemia & lymphoma 2009 Apr 50 (4): 566-70. Drain Stephen, Catherwood Mark A, Orr Nick, Galligan Leeona, Rea I Maeve, Hodkinson Clare, Drake Mary B, Kettle Paul J, Morris T C M Curly, Alexander H Den |
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Steroid biosynthesis and renal excretion in human essential hypertension: association with blood pressure and endogenous ouabain.
American journal of hypertension 2009 Apr 22 (4): 357-63. Tripodi Grazia, Citterio Lorena, Kouznetsova Tatiana, Lanzani Chiara, Florio Monica, Modica Rossana, Messaggio Elisabetta, Hamlyn John M, Zagato Laura, Bianchi Giuseppe, Staessen Jan A, Manunta Pao |
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