HuGE Literature Finder
Records 1-30
|
Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma.
Molecular cancer therapeutics 2019 Oct . Nassar Amin H, Hamieh Lana, Gray Kathryn P, Thorner Aaron R, Fay Andre P, Lasseter Kathryn D, Abou Alaiwi Sarah, Nuzzo Pier Vitale, Flippot Ronan, Krajewski Katherine M, Signoretti Sabina, Choueiri Toni K, Kwiatkowski David |
|
Co-occurring genetic alterations predict distant metastasis and poor efficacy of first-line EGFR-TKIs in EGFR-mutant NSCLC.
Journal of cancer research and clinical oncology 2019 Aug . Deng Li-Li, Gao Ge, Deng Hong-Bin, Wang Feng, Wang Zhi-Hui, Yang |
|
Targeted sequencing of circulating cell-free DNA in stage II-III resectable oesophageal squamous cell carcinoma patients.
BMC cancer 2019 Aug 19 (1): 818. Meng Pei, Wei Jiacong, Geng Yiqun, Chen Shaobin, Terpstra Miente Martijn, Huang Qiongyi, Zhang Qian, Su Zuoqing, Yu Wanchun, Su Min, Kok Klaas, van den Berg Anke, Gu Jia |
|
Molecular characterization of metaplastic breast carcinoma via next-generation sequencing.
Human pathology 2019 Apr 86 85-92. Zhai Jing, Giannini Gabriel, Ewalt Mark D, Zhang Elizabeth Y, Invernizzi Marta, Niland Joyce, Lai Lily |
|
Survival prediction of Tuberous Sclerosis Complex gene variant in patients with advanced non-small cell lung cancer treated with platinum doublet.
Bioscience reports 2019 Mar . Ryu Jeong-Seon, Lim Jun Hyeok, Kim Hyun-Jung, Kim Min Jeong, Park Mi Hwa, Kim Jung S |
|
Mutational profiles of persistent/recurrent laryngeal squamous cell carcinoma.
Head & neck 2019 Feb 41 (2): 423-428. Smith Joshua D, Birkeland Andrew C, Rosko Andrew J, Hoesli Rebecca C, Foltin Susan K, Swiecicki Paul, Mierzwa Michelle, Chinn Steven B, Shuman Andrew G, Malloy Kelly M, Casper Keith A, McLean Scott A, Wolf Gregory T, Bradford Carol R, Prince Mark E, Brenner John Chad, Spector Matthew |
|
Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.
British journal of cancer 2018 Sep 119 (6): 707-712. Bellmunt Joaquim, Lalani Aly-Khan A, Jacobus Sussana, Wankowicz Stephanie A, Polacek Laura, Takeda David Y, Harshman Lauren C, Wagle Nikhil, Moreno Irene, Lundgren Kevin, Bossé Dominick, Van Allen Eliezer M, Choueiri Toni K, Rosenberg Jonathan |
|
Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing.
Endocrine pathology 2018 Aug . Chang Ya-Sian, Chang Chun-Chi, Huang Hsi-Yuan, Lin Chien-Yu, Yeh Kun-Tu, Chang Jan-Gow |
|
The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: A study of 142 cases.
Histopathology 2018 Jul . Urano Makoto, Hirai Hideaki, Tada Yuichiro, Kawakita Daisuke, Shimura Tomotaka, Tsukahara Kiyoaki, Kano Satoshi, Ozawa Hiroyuki, Okami Kenji, Sato Yuichiro, Fushimi Chihiro, Shimizu Akira, Takase Soichiro, Okada Takuro, Sato Hiroki, Imanishi Yorihisa, Otsuka Kuninori, Watanabe Yoshihiro, Sakai Akihiro, Ebisumoto Koji, Togashi Takafumi, Ueki Yushi, Ota Hisayuki, Sato Yukiko, Saigusa Natsuki, Nakaguro Masato, Hanazawa Toyoyuki, Nagao Toshita |
|
Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance.
Lung cancer (Amsterdam, Netherlands) 2018 Jun 120 113-121. Du Meijun, Thompson Jonathan, Fisher Hannah, Zhang Peng, Huang Chiang-Ching, Wang Lia |
|
Analysis of the PI3K-AKT-mTOR pathway in penile cancer: evaluation of a therapeutically targetable pathway.
Oncotarget 2018 Mar 9 (22): 16074-16086. Adimonye Anthony, Stankiewicz Elzbieta, Kudahetti Sakunthala, Trevisan Giorgia, Tinwell Brendan, Corbishley Cathy, Lu Yong-Jie, Watkin Nick, Berney Dani |
|
Loss of PTEN in high grade advanced stage triple negative breast ductal cancers in African American women.
Pathology, research and practice 2018 Mar . Khan Farhan, Esnakula Ashwini, Ricks-Santi Luisel J, Zafar Rabia, Kanaan Yasmine, Naab Tamm |
|
Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study.
British journal of cancer 2018 Mar . Lau David K, Tay Rebecca Y, Yeung Yvonne H, Chionh Fiona, Mooi Jennifer, Murone Carmel, Skrinos Effie, Price Timothy J, Mariadason John M, Tebbutt Niall |
|
Analysis of 10 Adrenocortical Carcinoma Patients in the Cohort of the Precision Medicine Platform MONDTI.
Oncology 2018 Feb . Kieler Markus, Müllauer Leonhard, Koperek Oskar, Bianconi Daniela, Unseld Matthias, Raderer Markus, Prager Gerald |
|
Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival.
European journal of cancer (Oxford, England : 1990) 2018 Jan 91 47-55. Dubot C, Bernard V, Sablin M P, Vacher S, Chemlali W, Schnitzler A, Pierron G, Ait Rais K, Bessoltane N, Jeannot E, Klijanienko J, Mariani O, Jouffroy T, Calugaru V, Hoffmann C, Lesnik M, Badois N, Berger F, Le Tourneau C, Kamal M, Bieche |
|
Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis.
Lung cancer (Amsterdam, Netherlands) 2018 12 126 182-188. Udagawa Hibiki, Umemura Shigeki, Murakami Isao, Mimaki Sachiyo, Makinoshima Hideki, Ishii Genichiro, Miyoshi Tomohiro, Kirita Keisuke, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Tsuchihara Katsuya, Goto Koic |
|
Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.
European journal of cancer (Oxford, England : 1990) 2018 03 92 1-10. Verlingue Loic, Hollebecque Antoine, Lacroix Ludovic, Postel-Vinay Sophie, Varga Andrea, El Dakdouki Yolla, Baldini Capucine, Balheda Rastilav, Gazzah Anas, Michot Jean-Marie, Marabelle Aurélien, Mir Olivier, Arnedos Monica, Rouleau Etienne, Solary Eric, De Baere Thierry, Angevin Eric, Armand Jean-Pierre, Michiels Stefan, André Fabrice, Deutsch Eric, Scoazec Jean-Yves, Soria Jean-Charles, Massard Christop |
|
Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer.
Cancer chemotherapy and pharmacology 2017 Jul . Mbatchi Litaty C, Gassiot Matthieu, Pourquier Philippe, Goberna Alejando, Mahammedi Hakim, Mourey Loic, Joly Florence, Lumbroso Serge, Evrard Alexandre, Houede Nadi |
|
Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
British journal of cancer 2017 Jun 117 (1): 136-143. Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaet |
|
A phase II study of temsirolimus added to low-dose weekly carboplatin and paclitaxel for patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).
Annals of oncology : official journal of the European Society for Medical Oncology 2017 10 28 (10): 2533-2538. Dunn L A, Fury M G, Xiao H, Baxi S S, Sherman E J, Korte S, Pfister C, Haque S, Katabi N, Ho A L, Pfister D |
|
MicroRNA-Related Polymorphisms in PI3K/Akt/mTOR Pathway Genes Are Predictive of Limited-Disease Small Cell Lung Cancer Treatment Outcomes.
BioMed research international 2017 2017 6501385. Jiang Wei, Zhang Wenjue, Wu Lihong, Liu Lipin, Men Yu, Wang Jingbo, Liang Jun, Hui Zhouguang, Zhou Zongmei, Bi Nan, Wang Luh |
|
A phase I study of tivantinib in combination with temsirolimus in patients with advanced solid tumors.
Investigational new drugs 2016 Dec . Kyriakopoulos Christos E, Braden Amy M, Kolesar Jill M, Eickhoff Jens C, Bailey Howard H, Heideman Jennifer, Liu Glenn, Wisinski Kari |
|
Pharmacogenomic Markers of Targeted Therapy Toxicity in Patients with Metastatic Renal Cell Carcinoma.
European urology focus 2016 Dec 2 (6): 633-639. de Velasco Guillermo, Gray Kathryn P, Hamieh Lana, Urun Yuksel, Carol Hallie A, Fay Andre P, Signoretti Sabina, Kwiatkowski David J, McDermott David F, Freedman Matthew, Pomerantz Mark M, Choueiri Toni |
|
Everolimus in patients with advanced follicular-derived thyroid cancer; results of a phase II clinical trial.
The Journal of clinical endocrinology and metabolism 2016 Nov jc20162525. Schneider T C, de Wit D, Links T P, van Erp N P, van der Hoeven J J M, Gelderblom H, Roozen C F M, Bos M, Corver W E, van Wezel T, Smit J W A, Morreau H, Guchelaar H J, Kapiteijn |
|
Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy.
Scientific reports 2016 Nov 6 37576. Guo Qiaojuan, Lu Tianzhu, Chen Yan, Su Ying, Zheng Yuhong, Chen Zeng, Chen Chao, Lin Shaojun, Pan Jianji, Yuan Xiangl |
|
Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.
European urology 2016 Oct . Hsieh James J, Chen David, Wang Patricia I, Marker Mahtab, Redzematovic Almedina, Chen Ying-Bei, Selcuklu S Duygu, Weinhold Nils, Bouvier Nancy, Huberman Kety H, Bhanot Umesh, Chevinsky Michael S, Patel Parul, Pinciroli Patrizia, Won Helen H, You Daoqi, Viale Agnes, Lee William, Hakimi A Ari, Berger Michael F, Socci Nicholas D, Cheng Emily H, Knox Jennifer, Voss Martin H, Voi Maurizio, Motzer Robert |
|
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.
Nature communications 2016 Oct 7 13131. Chen Ying-Bei, Xu Jianing, Skanderup Anders Jacobsen, Dong Yiyu, Brannon A Rose, Wang Lu, Won Helen H, Wang Patricia I, Nanjangud Gouri J, Jungbluth Achim A, Li Wei, Ojeda Virginia, Hakimi A Ari, Voss Martin H, Schultz Nikolaus, Motzer Robert J, Russo Paul, Cheng Emily H, Giancotti Filippo G, Lee William, Berger Michael F, Tickoo Satish K, Reuter Victor E, Hsieh James |
|
Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach.
Oncotarget 2016 Oct . Fiorentino Michelangelo, Gruppioni Elisa, Massari Francesco, Giunchi Francesca, Altimari Annalisa, Ciccarese Chiara, Bimbatti Davide, Scarpa Aldo, Iacovelli Roberto, Porta Camillo, Virinder Sarhadi, Tortora Giampaolo, Artibani Walter, Schiavina Riccardo, Ardizzoni Andrea, Brunelli Matteo, Knuutila Sakari, Martignoni Gui |
|
Genomic profiling of large-cell neuroendocrine carcinoma of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Aug . Miyoshi Tomohiro, Umemura Shigeki, Matsumura Yuki, Mimaki Sachiyo, Tada Satoshi, Ishii Genichiro, Udagawa Hibiki, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Ohmatsu Hironobu, Aokage Keiju, Hishida Tomoyuki, Yoshida Junji, Nagai Kanji, Goto Koichi, Tsuboi Masahiro, Tsuchihara Katsu |
|
Tumor mutational load and immune parameters across metastatic Renal Cell Carcinoma (mRCC) risk groups.
Cancer immunology research 2016 Aug . De Velasco Guillermo, Miao Diana D, Voss Martin H, Hakimi A Ari, Hsieh James J, Tannir Nizar M, Tamboli Pheroze, Appleman Leonard J, Rathmell W Kimryn, Van Allen Eliezer, Choueiri Toni |
|
Comprehensive mutation profiling of mucinous gastric carcinoma.
The Journal of pathology 2016 Jun . Rokutan Hirofumi, Hosoda Fumie, Hama Natsuko, Nakamura Hiromi, Totoki Yasushi, Furukawa Eisaku, Arakawa Erika, Ohashi Shoko, Urushidate Tomoko, Satoh Hironori, Shimizu Hiroko, Igarashi Keiko, Yachida Shinichi, Katai Hitoshi, Taniguchi Hirokazu, Fukayama Masashi, Shibata Tatsuhi |
|
Effects of the multikinase inhibitors Sorafenib and Regorafenib in PTEN deficient neoplasias.
European journal of cancer (Oxford, England : 1990) 2016 Jun 63 74-87. Mirantes Cristina, Dosil Maria Alba, Eritja Núria, Felip Isidre, Gatius Sònia, Santacana Maria, Matias-Guiu Xavier, Dolcet Xavi |
|
Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma.
The Journal of pathology 2016 Jun . Tetzlaff Michael T, Singh Rajesh R, Seviour Elena G, Curry Jonathan L, Hudgens Courtney W, Bell Diana, Wimmer Daniel A, Ning Jing, Czerniak Bogdan A, Zhang Li, Davies Michael A, Prieto Victor G, Broaddus Russell R, Ram Prahlad, Luthra Rajyalakshmi, Esmaeli Bi |
|
Everolimus pharmacokinetics and its exposure-toxicity relationship in patients with thyroid cancer.
Cancer chemotherapy and pharmacology 2016 May . de Wit D, Schneider T C, Moes D J A R, Roozen C F M, den Hartigh J, Gelderblom H, Guchelaar H J, van der Hoeven J J, Links T P, Kapiteijn E, van Erp N |
|
Molecular Profiling of Clear Cell Ovarian Cancers: Identifying Potential Treatment Targets for Clinical Trials.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2016 May 26 (4): 648-54. Friedlander Michael L, Russell Kenneth, Millis Sherri, Gatalica Zoran, Bender Ryan, Voss Andre |
|
Study of single nucleotide polymorphisms of FBW7 and its substrate genes revealed a predictive factor for paclitaxel plus cisplatin chemotherapy in Chinese patients with advanced esophageal squamous cell carcinoma.
Oncotarget 2016 May . Liu Ying, Xu Shu Ning, Chen Yong Shun, Wu Xiao Yuan, Qiao Lei, Li Ke, Yuan Lo |
|
Targeted sequencing identifies genetic alterations that confer Primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium).
Oncotarget 2016 Apr . Lim Sun Min, Kim Hye Ryun, Cho Eun Kyung, Min Young Joo, Ahn Jin Seok, Ahn Myung-Ju, Park Keunchil, Cho Byoung Chul, Lee Ji-Hyun, Jeong Hye Cheol, Kim Eun Kyung, Kim Joo-Ha |
|
A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma.
Clinical colorectal cancer 2016 Mar . Bowles Daniel W, Kochenderfer Mark, Cohn Allen, Sideris Lucas, Nguyen Nghia, Cline-Burkhardt Vivian, Schnadig Ian, Choi Minsig, Nabell Lisle, Chaudhry Arvind, Ruxer Robert, Ucar Antonio, Hausman Diana, Walker Luke, Spira Alexander, Jimeno Anton |
|
Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic Renal Cell Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb . Kwiatkowski David J, Choueiri Toni K, Fay Andre P, Rini Brian I, Thorner Aaron R, De Velasco Guillermo, Tyburczy Magdalena, Hamieh Lana, Albiges Laurence, Agarwal Neeraj, Ho Thai H, Song Jiaxi, Pignon Jean-Christophe, Barrios Pablo M, Michaelson M Dror, Van Allen Eliezer M, Krajewski Katherine M, Porta Camillo, Pal Sumanta Kumar, Bellmunt Joaquim, McDermott David F, Heng Daniel Y C, Gray Kathryn P, Signoretti Sabi |
|
Targeted next-generation sequencing for molecular diagnosis of endometriosis-associated ovarian cancer.
Journal of molecular medicine (Berlin, Germany) 2016 Feb . Er Tze-Kiong, Su Yu-Fa, Wu Chun-Chieh, Chen Chih-Chieh, Wang Jing, Hsieh Tsung-Hua, Herreros-Villanueva Marta, Chen Wan-Tzu, Chen Yi-Ting, Liu Ta-Chih, Chen Hung-Sheng, Tsai Eing-M |
|
Identification of somatic gene mutations in penile squamous cell carcinoma.
Genes, chromosomes & cancer 2015 Oct 54 (10): 629-37. Ferrándiz-Pulido Carla, Hernández-Losa Javier, Masferrer Emili, Vivancos Ana, Somoza Rosa, Marés Roso, Valverde Claudia, Salvador Carlos, Placer Jose, Morote Juan, Pujol Ramon M, Ramon Santiago, Cajal Y, de Torres Ines, Toll Agusti, García-Patos Vicen |
|
Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes.
Oncotarget 2015 Oct . Hunter Sally M, Anglesio Michael S, Ryland Georgina L, Sharma Raghwa, Chiew Yoke-Eng, Rowley Simone M, Doyle Maria A, Li Jason, Gilks C Blake, Moss Phillip, Allan Prue E, Stephens Andrew N, Huntsman David G, deFazio Anna, Bowtell David D, , Gorringe Kylie L, Campbell Ian |
|
Immunohistochemical and molecular analysis of PI3K/AKT/mTOR pathway in esophageal carcinoma.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2015 Aug 123 (8): 639-47. Tasioudi Konstantia E, Sakellariou Stratigoula, Levidou Georgia, Theodorou Dimitrios, Michalopoulos Nikolaos V, Patsouris Efstratios, Korkolopoulou Penelope, Saetta Angelica |
|
Clinical usefulness of PI3K/Akt/mTOR genotyping in companion with other clinical variables in metastatic renal cell carcinoma patients treated with everolimus in the second and subsequent lines.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2015 Jul 26 (7): 1385-9. Bodnar L, Stec R, Cierniak S, Synowiec A, Wcis?o G, Jesiotr M, Koktysz R, Koz?owski W, Szczylik |
|
Genetic alterations of PIK3CA and tumor response in patients with locally advanced cervical squamous cell carcinoma treated with cisplatin-based concurrent chemoradiotherapy.
Experimental and molecular pathology 2015 Jun 98 (3): 407-10. Wang Juan, Chai Yan-lan, Wang Tao, Liu Jin-hui, Dai Peng-gao, Liu |
|
The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study.
The Journal of pathology 2015 May . Guerini-Rocco Elena, Hodi Zsolt, Piscuoglio Salvatore, Ng Charlotte Ky, Rakha Emad A, Schultheis Anne M, Marchiò Caterina, da Cruz Paula Arnaud, De Filippo Maria R, Martelotto Luciano G, De Mattos-Arruda Leticia, Edelweiss Marcia, Jungbluth Achim A, Fusco Nicola, Norton Larry, Weigelt Britta, Ellis Ian O, Reis-Filho Jorge |
|
Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.
Scientific reports 2015 5 8250. Zhu Jinhong, Wang Mengyun, Zhu Meiling, He Jin, Wang Jiu-Cun, Jin Li, Wang Xiao-Feng, Xiang Jia-Qing, Wei Qing |
|
Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women.
PloS one 2015 10 (3): e0120511. Deng Ling, Chen Jie, Zhong Xiao Rong, Luo Ting, Wang Yan Ping, Huang Hui Fen, Yin Li-Juan, Qiu Yan, Bu Hong, Lv Qing, Zheng Ho |
|
Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors.
PloS one 2015 10 (6): e0124711. Bellmunt Joaquim, Werner Lillian, Leow Jeffrey J, Mullane Stephanie A, Fay André P, Riester Markus, Van Hummelen Paul, Taplin Mary-Ellen, Choueiri Toni K, Van Allen Eliezer, Rosenberg Jonath |
|
Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor types.
Cell cycle (Georgetown, Tex.) 2015 14 (14): 2355-61. Schwaederle Maria, Elkin Sheryl K, Tomson Brett N, Carter Jennifer Levin, Kurzrock Razel |
|
Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience.
Oncotarget 2014 Nov 5 (22): 11168-79. Hou Ming-Mo, Liu Xiaochun, Wheler Jennifer, Naing Aung, Hong David, Coleman Robert L, Tsimberidou Apostolia, Janku Filip, Zinner Ralph, Lu Karen, Kurzrock Razelle, Fu Siqi |
|
Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome.
International journal of cancer. Journal international du cancer 2014 Sep 135 (6): 1330-42. Arai Eri, Sakamoto Hiromi, Ichikawa Hitoshi, Totsuka Hirohiko, Chiku Suenori, Gotoh Masahiro, Mori Taisuke, Nakatani Tamao, Ohnami Sumiko, Nakagawa Tohru, Fujimoto Hiroyuki, Wang Linghua, Aburatani Hiroyuki, Yoshida Teruhiko, Kanai Y |
|
A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Journal of cancer research and clinical oncology 2014 Aug 140 (8): 1399-411. Wang Xiaoting, Lin Youdong, Lan Fenghua, Yu Yinghao, Ouyang Xuenong, Wang Xuzhou, Huang Qiaojia, Wang Lie, Tan Jianming, Zheng Fe |
|
Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing.
Oncotarget 2014 May 5 (10): 3012-22. Janku Filip, Kaseb Ahmed O, Tsimberidou Apostolia M, Wolff Robert A, Kurzrock Razel |
|
Evaluation of PTEN, PI3K, MTOR, and KRAS expression and their clinical and prognostic relevance to differentiated thyroid carcinoma.
Contemporary oncology (Pozna?, Poland) 2014 18 (4): 234-40. Duman Berna B, Kara O?uz I, U?uz Aysum, Ates Berna |
|
PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup.
PloS one 2014 9 (2): e88291. Wang Lei, Hu Haichuan, Pan Yunjian, Wang Rui, Li Yuan, Shen Lei, Yu Yongfu, Li Hang, Cai Deng, Sun Yihua, Chen Haiqu |
|
TP53 and PIK3CA gene mutations in adenocarcinoma, squamous cell carcinoma and high-grade intraepithelial neoplasia of the cervix.
Journal of translational medicine 2014 12 (1): 255. Tornesello Maria Lina, Annunziata Clorinda, Buonaguro Luigi, Losito Simona, Greggi Stefano, Buonaguro Franco |
|
Associations between single-nucleotide polymorphisms in the PI3K-PTEN-AKT-mTOR pathway and increased risk of brain metastasis in patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Nov 19 (22): 6252-60. Li Qianxia, Yang Ju, Yu Qianqian, Wu Huanlei, Liu Bo, Xiong Huihua, Hu Guangyuan, Zhao Jing, Yuan Xianglin, Liao Zhongxi |
|
Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.
Molecular carcinogenesis 2013 Nov 52 Suppl 1 E70-9. He Jing, Wang Meng-Yun, Qiu Li-Xin, Zhu Mei-Ling, Shi Ting-Yan, Zhou Xiao-Yan, Sun Meng-Hong, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Li Jin, Yu Hong-Ping, Wei Qing- |
|
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers.
Cancer discovery 2013 Jul 3 (7): 761-9. Lui Vivian W Y, Hedberg Matthew L, Li Hua, Vangara Bhavana S, Pendleton Kelsey, Zeng Yan, Lu Yiling, Zhang Qiuhong, Du Yu, Gilbert Breean R, Freilino Maria, Sauerwein Sam, Peyser Noah D, Xiao Dong, Diergaarde Brenda, Wang Lin, Chiosea Simion, Seethala Raja, Johnson Jonas T, Kim Seungwon, Duvvuri Umamaheswar, Ferris Robert L, Romkes Marjorie, Nukui Tomoko, Kwok-Shing Ng Patrick, Garraway Levi A, Hammerman Peter S, Mills Gordon B, Grandis Jennifer |
|
Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013 Jun 8 (6): 788-95. Zhu Mei-Ling, Yu Hongping, Shi Ting-Yan, He Jing, Wang Meng-Yun, Li Qiao-Xin, Sun Meng-Hong, Jin Li, Yang Ya-Jun, Wang Jiu-Cun, Xiang Jia-Qing, Wei Qing- |
|
Cyclin D1, EGFR, and Akt/mTOR pathway. Potential prognostic markers in localized laryngeal squamous cell carcinoma.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2013 Mar 189 (3): 202-14. Dionysopoulos D, Pavlakis K, Kotoula V, Fountzilas E, Markou K, Karasmanis I, Angouridakis N, Nikolaou A, Kalogeras K T, Fountzilas |
|
Energy Balance, Polymorphisms in the mTOR Pathway, and Renal Cell Carcinoma Risk.
Journal of the National Cancer Institute 2013 Feb . Shu X, Lin J, Wood CG, Tannir NM, Wu X |
|
Single nucleotide polymorphisms and risk of recurrence of renal-cell carcinoma: a cohort study.
The Lancet. Oncology 2013 Jan 14 (1): 81-7. Schutz Fabio A B, Pomerantz Mark M, Gray Kathryn P, Atkins Michael B, Rosenberg Jonathan E, Hirsch Michelle S, McDermott David F, Lampron Megan E, Lee Gwo-Shu Mary, Signoretti Sabina, Kantoff Philip W, Freedman Matthew L, Choueiri Toni |
|
A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk.
PloS one 2012 7 (11): 11. Cao Q, Ju X, Li P, Meng X, Shao P, Cai H, Wang M, Zhang Z, Qin C, Yin C |
|
Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma.
Human pathology 2012 Dec 43 (12): 2197-206. Rahman Munmun, Nakayama Kentaro, Rahman Mohammed Tanjimur, Nakayama Naomi, Ishikawa Masako, Katagiri Atsuko, Iida Kouji, Nakayama Satoru, Otsuki Yoshiro, Shih Ie-Ming, Miyazaki Koh |
|
PIK3CA mutational status and overall survival in patients with cervical cancer treated with radical chemoradiotherapy.
Gynecologic oncology 2012 Dec . McIntyre JB, Wu J, Craighead PS, Phan T, Köbel M, Lees-Miller SP, Ghatage P, Magliocco AM, Doll CM |
|
[Association of genetic polymorphisms of key molecules in JAK/STAT signaling pathway with susceptibility of hepatocellular carcinoma].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2012 Feb 33 (2): 215-9. Xie Jia-xin, Yin Jian-hua, Zhang Qi, Pu Rui, Zhang Yu-wei, Lu Wen-ying, Cao Guang-w |
|
Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.
Carcinogenesis 2011 Apr 32 (4): 502-6. Wu I-Chen, Zhao Yang, Zhai Rihong, Liu Chen-yu, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Su Li, Heist Rebecca S, Kulke Matthew H, Liu Geoffrey, Christiani David |
|
Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 29 (4_suppl): 628. Lee S J, Kim J G, Chae Y S, Kang B W, Jeon S W, Park J S, Park J Y, Choi G S, Lee Y |
|
PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.
Lung cancer (Amsterdam, Netherlands) 2011 Jan 71 (1): 82-8. Pu Xia, Hildebrandt Michelle A T, Lu Charles, Lin Jie, Stewart David J, Ye Yuanqing, Gu Jian, Spitz Margaret R, Wu Xife |
|
A systematic study of gene mutations in urothelial carcinoma; inactivating mutations in TSC2 and PIK3R1.
PloS one 2011 6 (4): e18583. Sjödahl Gottfrid, Lauss Martin, Gudjonsson Sigurdur, Liedberg Fredrik, Halldén Christer, Chebil Gunilla, Månsson Wiking, Höglund Mattias, Lindgren Dav |
|
Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
PloS one 2011 6 (2): e16914. Campa Daniele, Hüsing Anika, Stein Angelika, Dostal Lucie, Boeing Heiner, Pischon Tobias, Tjønneland Anne, Roswall Nina, Overvad Kim, Østergaard Jane Nautrup, Rodríguez Laudina, Sala Núria, Sánchez Maria-José, Larrañaga Nerea, Huerta José María, Barricarte Aurelio, Khaw Kay-Tee, Wareham Nicholas, Travis Ruth C, Allen Naomi E, Lagiou Pagona, Trichopoulou Antonia, Trichopoulos Dimitrios, Palli Domenico, Sieri Sabina, Tumino Rosario, Sacerdote Carlotta, van Kranen Henk, Bueno-de-Mesquita H Bas, Hallmans Göran, Johansson Mattias, Romieu Isabelle, Jenab Mazda, Cox David G, Siddiq Afshan, Riboli Elio, Canzian Federico, Kaaks Rudo |
|
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Carcinogenesis 2010 Jul 31 (7): 1259-63. Liu Chen-Yu, Wu Michael C, Chen Feng, Ter-Minassian Monica, Asomaning Kofi, Zhai Rihong, Wang Zhaoxi, Su Li, Heist Rebecca S, Kulke Matthew H, Lin Xihong, Liu Geoffrey, Christiani David |
|
Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Oncology 2010 79 (3-4): 278-82. Kim Jong Gwang, Chae Yee Soo, Sohn Sang Kyun, Kang Byung Woog, Moon Joon Ho, Lee Soo Jung, Jeon Seong Woo, Park Jun Seok, Park Jin Young, Choi Gyu Se |
|
Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Feb 27 (6): 857-71. Hildebrandt Michelle A T, Yang Hushan, Hung Mien-Chie, Izzo Julie G, Huang Maosheng, Lin Jie, Ajani Jaffer A, Wu Xife |
- Page last reviewed:Mar 16, 2019
- Page last updated:Apr 02, 2020
- Content source: