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PIK3CA-mutations in breast cancer. Breast cancer research and treatment 2022 Oct . Reinhardt Kristin, Stückrath Kathrin, Hartung Carolin, Kaufhold Sandy, Uleer Christoph, Hanf Volker, Lantzsch Tillmann, Peschel Susanne, John Jutta, Pöhler Marleen, Bauer Marcus, Bürrig Friedrich Karl, Weigert Edith, Buchmann Jörg, Kantelhardt Eva Johanna, Thomssen Christoph, Vetter Marti |
PIK3CA Mutation is Associated with Poor Response to HER2-Targeted Therapy in Breast Cancer Patients. Cancer research and treatment 2022 Sep . Kim Ju Won, Lim Ah Reum, You Ji Young, Lee Jung Hyun, Song Sung Eun, Lee Nam Kwon, Jung Seung Pil, Cho Kyu Ran, Kim Cheol Yong, Park Kyong H |
PIK3CA mutation status, progression and survival in advanced HR?+?/HER2- breast cancer: a meta-analysis of published clinical trials. BMC cancer 2022 Sep 22 (1): 1002. Fillbrunn Mirko, Signorovitch James, André Fabrice, Wang Iris, Lorenzo Ines, Ridolfi Antonia, Park Jinhee, Dua Akanksha, Rugo Hope |
Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer. British journal of cancer 2022 Sep . Fernandez-Garcia Daniel, Nteliopoulos Georgios, Hastings Robert K, Rushton Amelia, Page Karen, Allsopp Rebecca C, Ambasager Bana, Gleason Kelly, Guttery David S, Ali Simak, Charles Coombes R, Shaw Jacqueline |
Clinicopathological characteristics and prognostic analysis of PIK3CA mutation in breast cancer patients in Northwest China. Pathology, research and practice 2022 Aug 238 154063. Lv Wei, Du Chong, Zhang Yinbing, Wu Fei, Jin Yaofeng, Chen Xi, Liu Xuan, Feng Cong, Ma Xingcong, Zhang Shuq |
Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant. NPJ breast cancer 2022 Jun 8 (1): 71. Correia Lizelle, Magno Ramiro, Xavier Joana M, de Almeida Bernardo P, Duarte Isabel, Esteves Filipa, Ghezzo Marinella, Eldridge Matthew, Sun Chong, Bosma Astrid, Mittempergher Lorenza, Marreiros Ana, Bernards Rene, Caldas Carlos, Chin Suet-Feung, Maia Ana-Tere |
Overall Survival With Palbociclib And Fulvestrant in Women With HR+/HER2- ABC: Updated Exploratory Analyses of PALOMA-3, a Double-Blind, Phase 3 Randomized Study. Clinical cancer research : an official journal of the American Association for Cancer Research 2022 May . Cristofanilli Massimo, Rugo Hope S, Im Seock-Ah, Slamon Dennis J, Harbeck Nadia, Bondarenko Igor, Masuda Norikazu, Colleoni Marco, DeMichele Angela, Loi Sherene, Iwata Hiroji, O'Leary Ben, André Fabrice, Loibl Sibylle, Bananis Eustratios, Liu Yuan, Huang Xin, Kim Sindy, Lechuga Frean Maria Jose, Turner Nicholas |
PIK3CA co-occurring mutations and copy-number gain in hormone receptor positive and HER2 negative breast cancer. NPJ breast cancer 2022 Feb 8 (1): 24. Migliaccio Ilenia, Paoli Marta, Risi Emanuela, Biagioni Chiara, Biganzoli Laura, Benelli Matteo, Malorni Lu |
Exploratory analysis of biomarkers associated with clinical outcomes from the study of palbociclib plus endocrine therapy in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer. Breast (Edinburgh, Scotland) 2022 Jan 62 52-60. Lee Soohyeon, Park Kyunghee, Kim Gun Min, Jung Kyung Hae, Kang Seok Yun, Park In Hae, Kim Jee Hyun, Ahn Hee Kyung, Park Woong-Yang, Im Seock-Ah, Park Yeon H |
Association of Pathway Mutations With Survival in Taiwanese Breast Cancers. Frontiers in oncology 2022 12 819555. Yang Po-Sheng, Chao Ying-Ting, Lung Chun-Fan, Liu Chien-Liang, Chang Yuan-Ching, Li Ker-Chau, Hsu Yi-Chiu |
Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature. International journal of cancer 2022 2 150 (12): 2072-2082. Johansson Annelie, Yu Nancy Y, Iftimi Adina, Tobin Nicholas P, van 't Veer Laura, Nordenskjöld Bo, Benz Christopher C, Fornander Tommy, Perez-Tenorio Gizeh, Stål Olle, Esserman Laura J, Yau Christina, Lindström Linda |
Clinical Significance of PIK3CA and ESR1 Mutations in Circulating Tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib plus Fulvestrant. Clinical cancer research : an official journal of the American Association for Cancer Research 2022 2 28 (8): 1500-1506. Tolaney Sara M, Toi Masakazu, Neven Patrick, Sohn Joohyuk, Grischke Eva-Maria, Llombart-Cussac Antonio, Soliman Hatem, Wang Hong, Wijayawardana Sameera, Jansen Valerie M, Litchfield Lacey M, Sledge George |
Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib. NPJ breast cancer 2022 2 8 (1): 22. Shishido Stephanie N, Masson Rahul, Xu Liya, Welter Lisa, Prabakar Rishvanth Kaliappan, D' Souza Anishka, Spicer Darcy, Kang Irene, Jayachandran Priya, Hicks James, Lu Janice, Kuhn Pet |
Exome sequencing reveals a distinct somatic genomic landscape in breast cancer from women with germline PTEN variants. American journal of human genetics 2022 08 109 (8): 1520-1533. Brewer Takae, Yehia Lamis, Bazeley Peter, Eng Char |
Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients. Journal of translational medicine 2022 05 20 (1): 211. Liao Hao, Zhang Jiayang, Zheng Tiantian, Liu Xiaoran, Zhong Jianxin, Shao Bin, Dong Xiaoxi, Wang Xiaohong, Du Pan, King Bonnie L, Jia Shidong, Yu Jianjun, Li Huipi |
Mutational landscape of pan-cancer patients with PIK3CA alterations in Chinese population. BMC medical genomics 2022 07 15 (1): 146. Huang Qingfeng, Zhou Yang, Wang Bowen, Zhao Yi, Zhang Fengxia, Ding Bow |
Phase II Study of Taselisib in PIK3CA-Mutated Solid Tumors Other Than Breast and Squamous Lung Cancer: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol I. JCO precision oncology 2022 2 6 e2100424. Krop Ian E, Jegede Opeyemi A, Grilley-Olson Juneko E, Lauring Josh D, Mitchell Edith P, Zwiebel James A, Gray Robert J, Wang Victoria, McShane Lisa M, Rubinstein Larry V, Patton David, Williams P Mickey, Hamilton Stanley R, Kono Scott A, Ford James M, Garcia Agustin A, Sui Xingwei D, Siegel Robert D, Slomovitz Brian M, Conley Barbara A, Arteaga Carlos L, Harris Lyndsay N, O'Dwyer Peter J, Chen Alice P, Flaherty Keith |
Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2022 2 28 (11): 2339-2348. Waks Adrienne G, Kim Dewey, Jain Esha, Snow Craig, Kirkner Gregory J, Rosenberg Shoshana M, Oh Coyin, Poorvu Philip D, Ruddy Kathryn J, Tamimi Rulla M, Peppercorn Jeffrey, Schapira Lidia, Borges Virginia F, Come Steven E, Brachtel Elena F, Warner Ellen, Collins Laura C, Partridge Ann H, Wagle Nikh |
Somatic loss of the remaining allele occurs approximately in half of CHEK2-driven breast cancers and is accompanied by a border-line increase of chromosomal instability. Breast cancer research and treatment 2022 1 192 (2): 283-291. Iyevleva Aglaya G, Aleksakhina Svetlana N, Sokolenko Anna P, Baskina Sofia V, Venina Aigul R, Anisimova Elena I, Bizin Ilya V, Ivantsov Alexandr O, Belysheva Yana V, Chernyakova Alexandra P, Togo Alexandr V, Imyanitov Evgeny |
Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population. Annals of medicine 2021 Dec 53 (1): 1358-1369. Wang Liye, Zhai Qinglian, Lu Qianyi, Lee Kaping, Zheng Qiufan, Hong Ruoxi, Wang Shus |
Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype. PLoS genetics 2021 Nov 17 (11): e1009876. Madsen Ralitsa R, Erickson Emily C, Rueda Oscar M, Robin Xavier, Caldas Carlos, Toker Alex, Semple Robert K, Vanhaesebroeck Ba |
TP53 mutations are associated with primary endocrine resistance in luminal early breast cancer. Cancer medicine 2021 Nov . Grote Isabel, Bartels Stephan, Kandt Leonie, Bollmann Laura, Christgen Henriette, Gronewold Malte, Raap Mieke, Lehmann Ulrich, Gluz Oleg, Nitz Ulrike, Kuemmel Sherko, Zu Eulenburg Christine, Braun Michael, Aktas Bahriye, Grischke Eva-Maria, Schumacher Claudia, Luedtke-Heckenkamp Kerstin, Kates Ronald, Wuerstlein Rachel, Graeser Monika, Harbeck Nadia, Christgen Matthias, Kreipe Ha |
A biomarker study in Peruvian males with breast cancer. World journal of clinical oncology 2021 Oct 12 (10): 926-934. Castaneda Carlos A, Castillo Miluska, Bernabe Luis A, Sanchez Joselyn, Torres Ebert, Suarez Nancy, Tello Katherine, Fuentes Hugo, Dunstan Jorge, De La Cruz Miguel, Cotrina Jose Manuel, Abugattas Julio, Guerra Henry, Gomez Henry |
PIK3CA mutation in non-metastatic triple-negative breast cancer as a potential biomarker of early relapse: A case report. World journal of clinical oncology 2021 Aug 12 (8): 702-711. Valencia Guillermo Arturo, Rioja Patricia, Morante Zaida, Araujo Jhajaira M, Vallejos Heberth Daniel, Guerra Henry, Gomez Henry |
Molecular Spectra and Frequency Patterns of Somatic Mutations in Arab Women with Breast Cancer. The oncologist 2021 Jul . Al-Shamsi Humaid O, Abu-Gheida Ibrahim, Abdulsamad Ahmed S, AlAwadhi Aydah, Alrawi Sadir, Musallam Khaled M, Arun Banu, Ibrahim Nuhad |
Dynamics of circulating tumor DNA during postoperative radiotherapy in patients with residual triple-negative breast cancer following neoadjuvant chemotherapy: a prospective observational study. Breast cancer research and treatment 2021 Jun . Kim Haeyoung, Kim Yeon Jeong, Park Donghyun, Park Woong-Yang, Choi Doo Ho, Park Won, Cho Won Kyung, Kim Nal |
Genomic profile of advanced breast cancer in circulating tumour DNA. Nature communications 2021 (1): 2423. Kingston Belinda, Cutts Rosalind J, Bye Hannah, Beaney Matthew, Walsh-Crestani Giselle, Hrebien Sarah, Swift Claire, Kilburn Lucy S, Kernaghan Sarah, Moretti Laura, Wilkinson Katie, Wardley Andrew M, Macpherson Iain R, Baird Richard D, Roylance Rebecca, Reis-Filho Jorge S, Hubank Michael, Faull Iris, Banks Kimberly C, Lanman Richard B, Garcia-Murillas Isaac, Bliss Judith M, Ring Alistair, Turner Nicholas |
Germline and Somatic mutations in postmenopausal breast cancer patients. Clinics (Sao Paulo, Brazil) 2021 76 e2837. Nagy Tauana Rodrigues, Maistro Simone, Encinas Giselly, Katayama Maria Lucia Hirata, Pereira Glaucia Fernanda de Lima, Gaburo-Júnior Nelson, Franco Lucas Augusto Moyses, Gouvêa Ana Carolina Ribeiro Chaves de, Diz Maria Del Pilar Estevez, Leite Luiz Antonio Senna, Folgueira Maria Aparecida Azevedo Koi |
Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients. Frontiers in medicine 2021 8 651904. Zheng Chun-Hui, Liu Zhao-Yun, Yuan Chen-Xi, Dong Xiao-Yun, Li Hai-Mei, Wang Jin-Jin, Zhang Zhao-Peng, Liu Hong-Ying, Ding Xiao-Yan, Wu Wendy, Wang Rui-Ru, Wang Yong-She |
Molecular Analysis of Luminal Androgen Receptor Reveals Activated Pathways and Potential Therapeutic Targets in Breast Cancer. Cancer genomics & proteomics 0 19 (4): 464-476. Stella Stefania, Vitale Silvia Rita, Massimino Michele, Motta Gianmarco, Longhitano Claudio, Lanzafame Katia, Martorana Federica, Fazzari Carmine, Vecchio Giada Maria, Tirrò Elena, Inzerilli Nicola, Carciotto Rosaria, Manzella Livia, Caruso Michele, Vigneri Pao |
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- Page last updated:Jan 27, 2023
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