HuGE Literature Finder
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| Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype. PLoS genetics 2021 Nov 17 (11): e1009876. Madsen Ralitsa R, Erickson Emily C, Rueda Oscar M, Robin Xavier, Caldas Carlos, Toker Alex, Semple Robert K, Vanhaesebroeck Ba |
| Sapanisertib Plus Exemestane or Fulvestrant in Women with Hormone Receptor-Positive/HER2-Negative Advanced or Metastatic Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Apr . Lim Bora, Potter David A, Salkeni Mohamad A, Silverman Paula, Haddad Tufia C, Forget Frederic, Awada Ahmad, Canon Jean-Luc, Danso Michael, Lortholary Alain, Bourgeois Hugues, Tan-Chiu Elizabeth, Vincent Sylvie, Bahamon Brittany, Galinsky Kevin J, Patel Chirag, Neuwirth Rachel, Leonard E Jane, Diamond Jennifer |
| Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients. Journal of advanced research 2020 Jul 24 149-157. Nassar Auhood, Abouelhoda Mohamed, Mansour Osman, Loutfy Samah A, Hafez Mohamed M, Gomaa M, Bahnassy Abeer, El-Din Youssef Amira Salah, Lotfy Mai M, Ismail Hoda, Ahmed Ola S, Abou-Bakr Amany Abd-Elhameed, Zekri Abdel-Rahman |
| Invasive apocrine carcinoma of the breast: clinicopathologic features and comprehensive genomic profiling of 18 pure triple-negative apocrine carcinomas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2020 Jun . Sun Xiangjie, Zuo Ke, Yao Qianlan, Zhou Shuling, Shui Ruohong, Xu Xiaoli, Bi Rui, Yu Baohua, Cheng Yufan, Tu Xiaoyu, Lu Hongfen, Yang Went |
| Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer. BMC cancer 2020 Apr 20 (1): 347. McCarthy Anne Marie, Kumar Nitya Pradeep, He Wei, Regan Susan, Welch Michaela, Moy Beverly, Iafrate A John, Chan Andrew T, Bardia Aditya, Armstrong Katri |
| Relationships between SNPs and prognosis of breast cancer and pathogenic mechanism. Molecular genetics & genomic medicine 2019 Jul e871. He Yaning, Liu Hui, Chen Qi, Shao Yingbo, Luo Sux |
| A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases. Cancers 2019 May 11 (5): . Tyran Marguerite, Carbuccia Nadine, Garnier Séverine, Guille Arnaud, Adelaïde José, Finetti Pascal, Toulzian Julien, Viens Patrice, Tallet Agnès, Goncalves Anthony, Metellus Philippe, Birnbaum Daniel, Chaffanet Max, Bertucci Franço |
| Molecular characterization of metaplastic breast carcinoma via next-generation sequencing. Human pathology 2019 Apr 86 85-92. Zhai Jing, Giannini Gabriel, Ewalt Mark D, Zhang Elizabeth Y, Invernizzi Marta, Niland Joyce, Lai Lily |
| Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609). Journal of hematology & oncology 2018 Oct 11 (1): 124. Liang Xu, Briaux Adrien, Becette Véronique, Benoist Camille, Boulai Anais, Chemlali Walid, Schnitzler Anne, Baulande Sylvain, Rivera Sofia, Mouret-Reynier Marie-Ange, Bouvet Laurence Venat, De La Motte Rouge Thibaut, Lemonnier Jérôme, Lerebours Florence, Callens Céli |
| LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases. Breast cancer research and treatment 2018 Jun . Van Swearingen Amanda E D, Siegel Marni B, Deal Allison M, Sambade Maria J, Hoyle Alan, Hayes D Neil, Jo Heejoon, Little Paul, Dees Elizabeth Claire, Muss Hyman, Jolly Trevor, Zagar Timothy M, Patel Nirali, Miller C Ryan, Parker Joel S, Smith J Keith, Fisher Julie, Shah Nikita, Nabell Lisle, Nanda Rita, Dillon Patrick, Abramson Vandana, Carey Lisa A, Anders Carey |
| Loss of PTEN in high grade advanced stage triple negative breast ductal cancers in African American women. Pathology, research and practice 2018 Mar . Khan Farhan, Esnakula Ashwini, Ricks-Santi Luisel J, Zafar Rabia, Kanaan Yasmine, Naab Tamm |
| Phase I/II clinical trial of everolimus combined with gemcitabine/cisplatin for metastatic triple-negative breast cancer. Journal of Cancer 2018 9 (7): 1145-1151. Park In Hae, Kong Sun-Young, Kwon Youngmee, Kim Min Kyeong, Sim Sung Hoon, Joo Jungnam, Lee Keun Se |
| Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN. Oncotarget 2017 Oct 8 (48): 84426-84433. Laes Jean-François, Sauvage Sebastien, Ghitti Grego |
| A Randomized Phase II Neoadjuvant Study of Cisplatin, Paclitaxel With or Without Everolimus in Patients with Stage II/III Triple-Negative Breast Cancer (TNBC): Responses and Long-term Outcome Correlated with Increased Frequency of DNA Damage Response Gene Mutations, TNBC Subtype, AR Status, and Ki67. Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Aug 23 (15): 4035-4045. Jovanovic Bojana, Mayer Ingrid A, Mayer Erica L, Abramson Vandana G, Bardia Aditya, Sanders Melinda E, Kuba M Gabriela, Estrada Monica V, Beeler J Scott, Shaver Timothy M, Johnson Kimberly C, Sanchez Violeta, Rosenbluth Jennifer M, Dillon Patrick M, Forero-Torres Andres, Chang Jenny C, Meszoely Ingrid M, Grau Ana M, Lehmann Brian D, Shyr Yu, Sheng Quanhu, Chen Sheau-Chiann, Arteaga Carlos L, Pietenpol Jennifer |
| Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium. Carcinogenesis 2017 Jun . Wang Shengfeng, Huo Dezheng, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Nathanson Katherine L, Nemesure Barbara, Ambs Stefan, Olopade Olufunmilayo I, Zheng Yongl |
| Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Apr . Pierobon Mariaelena, Ramos Corrine, Wong Shukmei, Hodge K Alex, Aldrich Jessica, Byron Sara A, Anthony Stephen P, Robert Nicholas J, Northfelt Donald W, Jahanzeb Mohammad, Vocila Linda, Wulfkuhle Julia D, Gambara Guido, Gallagher Rosa Isela, Dunetz Bryant, Hoke Nicholas, Dong Ting, Craig David W, Cristofanilli Massimo, Leyland Jones Brian, Liotta Lance, O'Shaughnessy Joyce A, Carpten John D, Petricoin Emanuel |
| Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer. PloS one 2017 12 (7): e0180192. Pascual Tomas, Apellániz-Ruiz María, Pernaut Cristina, Cueto-Felgueroso Cecilia, Villalba Pablo, Álvarez Carlos, Manso Luis, Inglada-Pérez Lucia, Robledo Mercedes, Rodríguez-Antona Cristina, Ciruelos E |
| Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis. PLoS medicine 2016 Dec 13 (12): e1002201. Lefebvre Celine, Bachelot Thomas, Filleron Thomas, Pedrero Marion, Campone Mario, Soria Jean-Charles, Massard Christophe, Lévy Christelle, Arnedos Monica, Lacroix-Triki Magali, Garrabey Julie, Boursin Yannick, Deloger Marc, Fu Yu, Commo Frédéric, Scott Véronique, Lacroix Ludovic, Dieci Maria Vittoria, Kamal Maud, Diéras Véronique, Gonçalves Anthony, Ferrerro Jean-Marc, Romieu Gilles, Vanlemmens Laurence, Mouret Reynier Marie-Ange, Théry Jean-Christophe, Le Du Fanny, Guiu Séverine, Dalenc Florence, Clapisson Gilles, Bonnefoi Hervé, Jimenez Marta, Le Tourneau Christophe, André Fabri |
| Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population. Oncotarget 2016 Sep 7 (36): 58174-58180. Zhao Yang, Diao Yan, Wang XiJing, Lin Shuai, Wang Meng, Kang HuaFeng, Yang PengTao, Dai Cong, Liu XingHan, Liu Kang, Li ShanLi, Zhu YuYao, Dai ZhiJ |
| Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women. Cancer causes & control : CCC 2016 08 27 (8): 965-76. Cheng Ting-Yuan David, Shankar Jyoti, Zirpoli Gary, Roberts Michelle R, Hong Chi-Chen, Bandera Elisa V, Ambrosone Christine B, Yao So |
| Prognostic value of PIK3CA mutation status, PTEN and androgen receptor expression for metastasis-free survival in HER2-positive breast cancer patients treated with trastuzumab in adjuvant setting. Polish journal of pathology : official journal of the Polish Society of Pathologists 2015 Jun 66 (2): 133-41. Adamczyk Agnieszka, Niemiec Joanna, Janecka Anna, Harazin-Lechowska Agnieszka, Ambicka Aleksandra, Grela-Wojewoda Aleksandra, Domaga?a-Haduch Ma?gorzata, Cedrych Ida, Majchrzyk Kaja, Kruczak Anna, Ry? Janusz, Jakubowicz Jer |
| The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study. The Journal of pathology 2015 May . Guerini-Rocco Elena, Hodi Zsolt, Piscuoglio Salvatore, Ng Charlotte Ky, Rakha Emad A, Schultheis Anne M, Marchiò Caterina, da Cruz Paula Arnaud, De Filippo Maria R, Martelotto Luciano G, De Mattos-Arruda Leticia, Edelweiss Marcia, Jungbluth Achim A, Fusco Nicola, Norton Larry, Weigelt Britta, Ellis Ian O, Reis-Filho Jorge |
| Comprehensive DNA Methylation and Extensive Mutation Analyses of HER2-Positive Breast Cancer. Oncology 2015 88 (6): 377-84. Yamaguchi Takeshi, Mukai Hirofumi, Yamashita Satoshi, Fujii Satoshi, Ushijima Toshika |
| Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women. PloS one 2015 10 (3): e0120511. Deng Ling, Chen Jie, Zhong Xiao Rong, Luo Ting, Wang Yan Ping, Huang Hui Fen, Yin Li-Juan, Qiu Yan, Bu Hong, Lv Qing, Zheng Ho |
| Association between germline single nucleotide polymorphisms in the PI3K-AKT-mTOR pathway, obesity, and breast cancer disease-free survival. Breast cancer research and treatment 2014 Sep 147 (2): 381-7. Pande Mala, Bondy Melissa L, Do Kim-Anh, Sahin Aysegul A, Ying Jun, Mills Gordon B, Thompson Patricia A, Brewster Abenaa |
| A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: implications for clinical practice. The oncologist 2014 May 19 (5): 453-8. Vasan Neil, Yelensky Roman, Wang Kai, Moulder Stacy, Dzimitrowicz Hannah, Avritscher Rony, Wang Baliang, Wu Yun, Cronin Maureen T, Palmer Gary, Symmans W Fraser, Miller Vincent A, Stephens Philip, Pusztai Laj |
| Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway. Oncotarget 2014 May 5 (10): 3029-38. Wheler Jennifer J, Moulder Stacy L, Naing Aung, Janku Filip, Piha-Paul Sarina A, Falchook Gerald S, Zinner Ralph, Tsimberidou Apostolia M, Fu Siqing, Hong David S, Atkins Johnique T, Yelensky Roman, Stephens Philip J, Kurzrock Razel |
| PI3KCA mutation status is of limited prognostic relevance in ER-positive breast cancer patients treated with hormone therapy. Virchows Archiv : an international journal of pathology 2014 Jan 464 (1): 85-93. Cuorvo Lucia Veronica, Verderio Paolo, Ciniselli Chiara Maura, Girlando Salvatore, Decarli Nicola, Leonardi Elena, Ferro Antonella, Caldara Alessia, Triolo Renza, Eccher Claudio, Cantaloni Chiara, Mauri Francesco, Seckl Michael, Volante Marco, Buttitta Fiamma, Marchetti Antonio, Silvia Quattrone, Galligioni Enzo, Palma Paolo Dalla, Barbareschi Matt |
| PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients. Breast cancer research : BCR 2014 16 (1): R13. Beelen Karin, Opdam Mark, Severson Tesa M, Koornstra Rutger H T, Vincent Andrew D, Wesseling Jelle, Muris Jettie J, Berns Els M J J, Vermorken Jan B, van Diest Paul J, Linn Sabine |
| Molecular Analysis of Luminal Androgen Receptor Reveals Activated Pathways and Potential Therapeutic Targets in Breast Cancer. Cancer genomics & proteomics 0 19 (4): 464-476. Stella Stefania, Vitale Silvia Rita, Massimino Michele, Motta Gianmarco, Longhitano Claudio, Lanzafame Katia, Martorana Federica, Fazzari Carmine, Vecchio Giada Maria, Tirrò Elena, Inzerilli Nicola, Carciotto Rosaria, Manzella Livia, Caruso Michele, Vigneri Pao |
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- Page last updated:Aug 10, 2022
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