HuGE Literature Finder
Records 1-30
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Clinical, histopathological, and molecular analyses of IDH-wild-type WHO grade II-III gliomas to establish genetic predictors of poor prognosis.
Brain tumor pathology 2019 Jul . Kuwahara Kiyonori, Ohba Shigeo, Nakae Shunsuke, Hattori Natsuki, Pareira Eriel Sandika, Yamada Seiji, Sasaki Hikaru, Abe Masato, Hasegawa Mitsuhiro, Hirose Yuic |
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High frequency of H3K27M immunopositivity in adult thalamic glioblastoma.
Neuropathology : official journal of the Japanese Society of Neuropathology 2019 Apr 39 (2): 78-84. Rao Shilpa, Kanuri Nandaki N, Nimbalkar Vidya, Arivazhagan Arimappamagan, Santosh Va |
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Identification of potential biomarkers related to glioma survival by gene expression profile analysis.
BMC medical genomics 2019 Mar 11 (Suppl 7): 34. Hsu Justin Bo-Kai, Chang Tzu-Hao, Lee Gilbert Aaron, Lee Tzong-Yi, Chen Cheng- |
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Incidence and clinicopathologic features of H3 K27M mutations in adults with radiographically-determined midline gliomas.
Journal of neuro-oncology 2019 Mar . Schreck Karisa C, Ranjan Surabhi, Skorupan Nebojša, Bettegowda Chetan, Eberhart Charles G, Ames Heather M, Holdhoff Matthi |
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Prognostic Role of Chicken Ovalbumin Upstream Promoter Transcription Factor II in Isocitrate Dehydrogenase-Mutant Glioma with 1p19q Co-Deletion.
Journal of molecular neuroscience : MN 2019 Mar . Chai Yi, Liu Wei, Wang Caixia, Rao Minchao, Zhang Yu |
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The contribution of the rs55705857 G allele to familial cancer risk as estimated in the Utah population database.
BMC cancer 2019 Mar 19 (1): 190. Hummel Sarah, Kohlmann Wendy, Kollmeyer Thomas M, Jenkins Robert, Sonnen Joshua, Palmer Cheryl A, Colman Howard, Abbott Diana, Cannon-Albright Lisa, Cohen Adam |
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Impact of Multifocality and Molecular Markers on Survival of Glioblastoma.
World neurosurgery 2019 Feb 122 e461-e466. Ahmadipour Yahya, Jabbarli Ramazan, Gembruch Oliver, Pierscianek Daniela, Darkwah Oppong Marvin, Dammann Philipp, Wrede Karsten, Özkan Neriman, Müller Oliver, Sure Ulrich, El Hindy Nicol |
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The association between longer relative leukocyte telomere length and risk of glioma is independent of the potentially confounding factors allergy, BMI, and smoking.
Cancer causes & control : CCC 2019 Feb 30 (2): 177-185. Andersson Ulrika, Degerman Sofie, Dahlin Anna M, Wibom Carl, Johansson Gunnar, Bondy Melissa L, Melin Beatrice |
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The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
Brain pathology (Zurich, Switzerland) 2019 Jan 29 (1): 85-96. Phillips Joanna J, Gong Henry, Chen Katharine, Joseph Nancy M, van Ziffle Jessica, Bastian Boris C, Grenert James P, Kline Cassie N, Mueller Sabine, Banerjee Anuradha, Nicolaides Theodore, Gupta Nalin, Berger Mitchel S, Lee Han S, Pekmezci Melike, Tihan Tarik, Bollen Andrew W, Perry Arie, Shieh Joseph T C, Solomon David |
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IDH mutations but not TERTp mutations are associated with seizures in lower-grade gliomas.
Medicine 2018 Dec 97 (50): e13675. Duan Wen-Chao, Wang Li, Li Ke, Wang Wei-Wei, Zhan Yun-Bo, Zhang Feng-Jiang, Yu Bin, Bai Ya-Hui, Wang Yan-Min, Ji Yu-Chen, Zhou Jin-Qiao, Liu Xian-Zhi, Zhang Zhen- |
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BRAF V600E, TERT, and IDH2 mutations in pleomorphic xanthoastrocytoma: Observations from a large case-series study.
World neurosurgery 2018 Sep . Ma Chengxin, Feng Rui, Chen Hong, Farrukh Hameed N U, Aibaidula Abudumijit, Song Yanyan, Wu Jinso |
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Granular cell astrocytoma: an aggressive IDH-wildtype diffuse gliomarwith molecular genetic features of primary glioblastoma.
Brain pathology (Zurich, Switzerland) 2018 Sep . Vizcaino M Adelita, Palsgrove Doreen N, Yuan Ming, Giannini Caterina, Cabrera-Aldana Eibar Ernesto, Pallavajjala Aparna, Burger Peter C, Rodriguez Fausto |
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Predicting IDH genotype in gliomas using FET PET radiomics.
Scientific reports 2018 Sep 8 (1): 13328. Lohmann Philipp, Lerche Christoph, Bauer Elena K, Steger Jan, Stoffels Gabriele, Blau Tobias, Dunkl Veronika, Kocher Martin, Viswanathan Shivakumar, Filss Christian P, Stegmayr Carina, Ruge Maximillian I, Neumaier Bernd, Shah Nadim J, Fink Gereon R, Langen Karl-Josef, Galldiks Norbe |
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Molecular Study of Long-Term Survivors of Glioblastoma by Gene-Targeted Next-Generation Sequencing.
Journal of neuropathology and experimental neurology 2018 Aug 77 (8): 710-716. Cantero Diana, Rodríguez de Lope Ángel, Moreno de la Presa Raquel, Sepúlveda Juan M, Borrás José M, Castresana Javier S, D'Haene Nicky, García Juan F, Salmon Isabelle, Mollejo Manuela, Rey Juan A, Hernández-Laín Aurelio, Meléndez Bárba |
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Non-small cell lung cancers with isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations.
Human pathology 2018 Aug 78 138-143. Toth Laura N, de Abreu Francine B, Tafe Laura |
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Use of metformin and survival of patients with high-grade glioma.
International journal of cancer 2018 Aug . Seliger Corinna, Luber Christian, Gerken Michael, Schaertl Julia, Proescholdt Martin, Riemenschneider Markus J, Meier Christoph R, Bogdahn Ulrich, Leitzmann Michael F, Klinkhammer-Schalke Monika, Hau Pet |
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TERT promoter mutation detection in cell-free tumor-derived DNA in patients with IDH wild-type glioblastomas - a pilot prospective study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jun . Juratli Tareq A, Stasik Sebastian, Zolal Amir, Schuster Caroline, Richter Sven, Daubner Dirk, Juratli Mazen A, Thowe Rachel T, Hennig Silke, Makina Meriem, Meinhardt Matthias, Lautenschlaeger Tim, Schackert Gabriele, Krex Dietmar, Thiede Christi |
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IDH-mutated astrocytomas with 19q-loss constitute a subgroup that confers better prognosis.
Cancer science 2018 May . Otani Ryohei, Uzuka Takeo, Higuchi Fumi, Matsuda Hadzki, Nomura Masashi, Tanaka Shota, Mukasa Akitake, Ichimura Koichi, Kim Phyo, Ueki Keisu |
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Clinical implications of TERT promoter mutation on IDH mutation and MGMT promoter methylation in diffuse gliomas.
Pathology, research and practice 2018 Apr . Kim Hyun Sik, Kwon Mi Jung, Song Joon Ho, Kim Eun Soo, Kim Ho Young, Min Kyueng-Wh |
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Prevalence of the single-nucleotide polymorphism rs11554137 (IDH1 105GGT ) in brain tumors of a cohort of Italian patients.
Scientific reports 2018 Mar 8 (1): 4459. Acquaviva Giorgia, Visani Michela, de Biase Dario, Marucci Gianluca, Franceschi Enrico, Tosoni Alicia, Brandes Alba A, Rhoden Kerry J, Pession Annalisa, Tallini Giovan |
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Clinical prognostic value of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in glioblastoma.
Journal of neuro-oncology 2018 Feb . Mistry Akshitkumar M, Vnencak-Jones Cindy L, Mobley Bret |
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High-frequency oscillations in awake patients undergoing brain tumor-related epilepsy surgery.
Neurology 2018 Feb . Feyissa Anteneh M, Worrell Gregory A, Tatum William O, Mahato Deependra, Brinkmann Benjamin H, Rosenfeld Steven S, ReFaey Karim, Bechtle Perry S, Quinones-Hinojosa Alfre |
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Association between IDH1/2 mutation and preoperative seizures in patients with low-grade versus high-grade glioma: a systematic review and meta-analysis.
World neurosurgery 2017 Dec . Phan Kevin, Ng Wyatt, Lu Victor M, McDonald Kerrie L, Fairhall Jacob, Reddy Rajesh, Wilson Pet |
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BRAF V600E mutation is a significant prognosticator of the tumour regrowth rate in brainstem gangliogliomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2017 Dec 46 50-57. Chen Xin, Pan Changcun, Zhang Peng, Xu Cheng, Sun Yu, Yu Hai, Wu Yuliang, Geng Yibo, Zuo Pengcheng, Wu Zhen, Zhang Junting, Zhang Liw |
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Characteristics of cerebellar glioblastomas in adults.
Journal of neuro-oncology 2017 Dec . Picart Thiébaud, Barritault Marc, Berthillier Julien, Meyronet David, Vasiljevic Alexandre, Frappaz Didier, Honnorat Jérôme, Jouanneau Emmanuel, Poncet Delphine, Ducray François, Guyotat Jacqu |
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TERT promoter mutation and its interaction with IDH mutations in glioma: Combined TERT promoter and IDH mutations stratifies lower-grade glioma into distinct survival subgroups-A meta-analysis of aggregate data.
Critical reviews in oncology/hematology 2017 Dec 120 1-9. Vuong Huy Gia, Altibi Ahmed M A, Duong Uyen N P, Ngo Hanh T T, Pham Thong Quang, Chan Aden Ka-Yin, Park Chul-Kee, Fung Kar-Ming, Hassell Lew |
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A glycolysis-based ten-gene signature correlates with the clinical outcome, molecular subtype and IDH1 mutation in glioblastoma.
Journal of genetics and genomics = Yi chuan xue bao 2017 Nov 44 (11): 519-530. Chen Cong, Shi Yu, Li Yong, He Zhi-Cheng, Zhou Kai, Zhang Xiao-Ning, Yang Kai-Di, Wu Jin-Rong, Kung Hsiang-Fu, Ping Yi-Fang, Bian Xiu- |
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Paradoxical prognostic impact of TERT promoter mutations in gliomas depends on different histological and genetic backgrounds.
CNS neuroscience & therapeutics 2017 Oct 23 (10): 790-797. You Hao, Wu Yao, Chang Kai, Shi Xiao, Chen Xin-Da, Yan Wei, Li R |
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IDH mutation status trumps the Pignatti risk score as a prognostic marker in low-grade gliomas.
Journal of neuro-oncology 2017 Sep . Etxaniz Olatz, Carrato Cristina, de Aguirre Itziar, Queralt Cristina, Muñoz Ana, Ramirez José L, Rosell Rafael, Villà Salvador, Diaz Rocio, Estival Ana, Teixidor Pilar, Indacochea Alberto, Ahjal Sara, Vilà Laia, Balañá Car |
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The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.
Acta neuropathologica communications 2017 Aug 5 (1): 62. Lee Yujin, Koh Jaemoon, Kim Seong-Ik, Won Jae Kyung, Park Chul-Kee, Choi Seung Hong, Park Sung-H |
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Non-canonical IDH1 and IDH2 mutations: a clonal and relevant event in an Italian cohort of gliomas classified according to the 2016 World Health Organization (WHO) criteria.
Journal of neuro-oncology 2017 Jul . Visani Michela, Acquaviva Giorgia, Marucci Gianluca, Paccapelo Alexandro, Mura Antonella, Franceschi Enrico, Grifoni Daniela, Pession Annalisa, Tallini Giovanni, Brandes Alba A, de Biase Dar |
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Prognostic relevance of genetic alterations in diffuse lower-grade gliomas.
Neuro-oncology 2017 Jul . Aoki Kosuke, Nakamura Hideo, Suzuki Hiromichi, Matsuo Keitaro, Kataoka Keisuke, Shimamura Teppei, Motomura Kazuya, Ohka Fumiharu, Shiina Satoshi, Yamamoto Takashi, Nagata Yasunobu, Yoshizato Tetsuichi, Mizoguchi Masahiro, Abe Tatsuya, Momii Yasutomo, Muragaki Yoshihiro, Watanabe Reiko, Ito Ichiro, Sanada Masashi, Yajima Hironori, Morita Naoya, Takeuchi Ichiro, Miyano Satoru, Wakabayashi Toshihiko, Ogawa Seishi, Natsume Atsus |
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The Role of Extent of Resection in IDH1 Wild-Type or Mutant Low-Grade Gliomas.
Neurosurgery 2017 Jul . Patel Toral, Bander Evan D, Venn Rachael A, Powell Tiffany, Cederquist Gustav Young-Min, Schaefer Peter M, Puchi Luis A, Akhmerov Akbarshakh, Ogilvie Shahiba, Reiner Anne S, Moussazadeh Nelson, Tabar Vivia |
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Genetic landscape of extreme responders with anaplastic oligodendroglioma.
Oncotarget 2017 May 8 (22): 35523-35531. Holdhoff Matthias, Cairncross Gregory J, Kollmeyer Thomas M, Zhang Ming, Zhang Peixin, Mehta Minesh P, Werner-Wasik Maria, Souhami Luis, Bahary Jean-Paul, Kwok Young, Hartford Alan C, Chakravarti Arnab, Yegnasubramanian Srinivasan, Vogelstein Bert, Papadopoulos Nickolas, Kinzler Kenneth, Jenkins Robert B, Bettegowda Chet |
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R132H Mutation in IDH1 Gene is Associated with Increased Tumor HIF1-Alpha and Serum VEGF Levels in Primary Glioblastoma Multiforme.
Annals of clinical and laboratory science 2017 May 47 (3): 362-364. Yalaza Cem, Ak Handan, Cagli Mehmet Sedat, Ozgiray Erkin, Atay Sevcan, Aydin Hikmet Hak |
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Prognostic Relevance of Tumor Purity and TERT Promoter Mutations on MGMT Promoter Methylation in Glioblastoma.
Molecular cancer research : MCR 2017 Feb . Schulze Heuling Eva, Knab Felix, Radke Josefine, Eskilsson Eskil, Martinez-Ledesma Emmanuel, Koch Arend, Czabanka Marcus, Dieterich Christoph, Verhaak Roel G, Harms Christoph, Euskirchen Phili |
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Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 2017 30 (5): 361-371. Houdova Megova M, Drábek J, Dwight Z, Trojanec R, Koudeláková V, Vrbková J, Kalita O, Mlcochova S, Rabcanova M, Hajdúch |
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Prediction of genetic subgroups in adult supra tentorial gliomas by pre- and intraoperative parameters.
Journal of neuro-oncology 2016 Nov . Nakae Shunsuke, Murayama Kazuhiro, Sasaki Hikaru, Kumon Masanobu, Nishiyama Yuya, Ohba Shigeo, Adachi Kazuhide, Nagahisa Shinya, Hayashi Takuro, Inamasu Joji, Abe Masato, Hasegawa Mitsuhiro, Hirose Yuic |
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IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy.
Clinical neurology and neurosurgery 2016 Oct 151 31-36. Li Hailong, Li Jiye, Cheng Gang, Zhang Jianning, Li Xuezh |
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Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.
Oncotarget 2016 Oct 7 (40): 64615-64630. Li Yan-Xi, Shi Zhifeng, Aibaidula Abudumijiti, Chen Hong, Tang Qisheng, Li Kay Ka-Wai, Chung Nellie Yuk-Fei, Chan Danny Tat-Ming, Poon Wai Sang, Mao Ying, Wu Jinsong, Zhou Liangfu, Chan Aden Ka-Yin, Ng Ho-Keu |
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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
Oncotarget 2016 Sep . Roodakker Kenney R, Elsir Tamador, Edqvist Per-Henrik D, Hägerstrand Daniel, Carlson Joseph, Lysiak Malgorzata, Henriksson Roger, Pontén Fredrik, Rosell Johan, Söderkvist Peter, Stupp Roger, Tchougounova Elena, Nistér Monica, Malmström Annika, Smits An |
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GBM-associated mutations and altered protein expression are more common in young patients.
Oncotarget 2016 Aug . Ferguson Sherise D, Xiu Joanne, Weathers Shiao-Pei, Zhou Shouhao, Kesari Santosh, Weiss Stephanie E, Verhaak Roeland G, Hohl Raymond J, Barger Geoffrey R, Reddy Sandeep K, Heimberger Amy |
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Human TERT promoter mutation enables survival advantage from MGMT promoter methylation in IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy.
Neuro-oncology 2016 Aug . Nguyen HuyTram N, Lie Amy, Li Tie, Chowdhury Reshmi, Liu Fei, Ozer Byram, Wei Bowen, Green Richard M, Ellingson Benjamin M, Wang He-Jing, Elashoff Robert, Liau Linda M, Yong William H, Nghiemphu Phioanh L, Cloughesy Timothy, Lai Albe |
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Putamen involvement and survival outcomes in patients with insular low-grade gliomas.
Journal of neurosurgery 2016 Aug 1-7. Wang Yongheng, Wang Yinyan, Fan Xing, Li Shaowu, Liu Xing, Wang Jiangfei, Jiang T |
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The Correlation Between 1p/19q Codeletion, IDH1 Mutation, p53 Overexpression and Their Prognostic Roles in 41 Turkish Anaplastic Oligodendroglioma Patients.
Turkish neurosurgery 2016 Aug . Hacisalihoglu Payam, Kucukodaci Zafer, Gundogdu Gokcen, Bilgic Bil |
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The impact of MGMT methylation and IDH-1 mutation on long-term outcome for glioblastoma treated with chemoradiotherapy.
Acta neurochirurgica 2016 Aug . Millward Christopher P, Brodbelt Andrew R, Haylock Brian, Zakaria Rasheed, Baborie Atik, Crooks Daniel, Husband David, Shenoy Aditya, Wong Helen, Jenkinson Michael |
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An analysis of 170 glioma patients and systematic review to investigate the association between IDH-1 mutations and preoperative glioma-related epilepsy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2016 Jul . Yang Yuan, Mao Qing, Wang Xiang, Liu Yanhui, Mao Yunhe, Zhou Qiao, Luo Jiew |
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Sex-specific clinicopathological significance of novel (Frizzled-7) and established (MGMT, IDH1) biomarkers in glioblastoma.
Oncotarget 2016 Jul . Schiffgens Salveena, Wilkens Ludwig, Brandes Alba A, Meier Tatiana, Franceschi Enrico, Ermani Mario, Hartmann Christian, Sandalcioglu I Erol, Dumitru Claudia |
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Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas.
Neuro-oncology 2016 Jun . Zhang Biqi, Chang Ken, Ramkissoon Shakti, Tanguturi Shyam, Bi Wenya Linda, Reardon David A, Ligon Keith L, Alexander Brian M, Wen Patrick Y, Huang Raymond |
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An IDH1-mutated primary gliosarcoma: case report.
Journal of neurosurgery 2016 May 1-5. Hsieh Jason K, Hong Christopher S, Manjila Sunil, Cohen Mark L, Lo Simon, Rogers Lisa, Sloan Andrew |
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Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.
Journal of neuro-oncology 2016 May 127 (3): 483-92. Ghasimi Soma, Wibom Carl, Dahlin Anna M, Brännström Thomas, Golovleva Irina, Andersson Ulrika, Melin Beatri |
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Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes.
Oncotarget 2016 Apr 7 (15): 20486-95. Zhao Hua, Heimberger Amy B, Lu Zhimin, Wu Xifeng, Hodges Tiffany R, Song Renduo, Shen J |
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Isocitrate Dehydrogenase (IDH)1/2 Mutations as Prognostic Markers in Patients With Glioblastomas.
Medicine 2016 Mar 95 (9): e2583. Chen Jun-Rui, Yao Yu, Xu Hong-Zhi, Qin Zhi-Yo |
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IDH mutation is associated with higher risk of malignant transformation in low-grade glioma.
Journal of neuro-oncology 2016 Jan . Leu Severina, von Felten Stefanie, Frank Stephan, Boulay Jean-Louis, Mariani Lui |
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Prognostic significance of histomolecular subgroups of adult anaplastic (WHO Grade III) gliomas: applying the 'integrated' diagnosis approach.
Journal of clinical pathology 2016 Jan . Rajmohan K S, Sugur Harsha S, Shwetha S D, Ramesh Arvind, Thennarasu Kandavel, Pandey Paritosh, Arivazhagan Arimappamagan, Santosh Va |
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A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
Acta neuropathologica communications 2016 4 (1): 79. Arita Hideyuki, Yamasaki Kai, Matsushita Yuko, Nakamura Taishi, Shimokawa Asanao, Takami Hirokazu, Tanaka Shota, Mukasa Akitake, Shirahata Mitsuaki, Shimizu Saki, Suzuki Kaori, Saito Kuniaki, Kobayashi Keiichi, Higuchi Fumi, Uzuka Takeo, Otani Ryohei, Tamura Kaoru, Sumita Kazutaka, Ohno Makoto, Miyakita Yasuji, Kagawa Naoki, Hashimoto Naoya, Hatae Ryusuke, Yoshimoto Koji, Shinojima Naoki, Nakamura Hideo, Kanemura Yonehiro, Okita Yoshiko, Kinoshita Manabu, Ishibashi Kenichi, Shofuda Tomoko, Kodama Yoshinori, Mori Kanji, Tomogane Yusuke, Fukai Junya, Fujita Koji, Terakawa Yuzo, Tsuyuguchi Naohiro, Moriuchi Shusuke, Nonaka Masahiro, Suzuki Hiroyoshi, Shibuya Makoto, Maehara Taketoshi, Saito Nobuhito, Nagane Motoo, Kawahara Nobutaka, Ueki Keisuke, Yoshimine Toshiki, Miyaoka Etsuo, Nishikawa Ryo, Komori Takashi, Narita Yoshitaka, Ichimura Koic |
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ATRX immunostaining predicts IDH and H3F3A status in gliomas.
Acta neuropathologica communications 2016 4 (1): 60. Ebrahimi Azadeh, Skardelly Marco, Bonzheim Irina, Ott Ines, Mühleisen Helmut, Eckert Franziska, Tabatabai Ghazaleh, Schittenhelm Je |
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Prevalence of IDH1/2 Mutations in Different Subtypes of Glioma in the North-East Population of Morocco.
Asian Pacific journal of cancer prevention : APJCP 2016 17 (5): 2649-53. Senhaji Nadia, Louati Sara, Chbani Laila, Bardai Sanae El, Mikou Karima, Maaroufi Mustafa, Benzagmout Mohammed, Faiz Mohammed Chaoui El, Marie Yannick, Mokhtari Karima, Idbaih Ahmed, Amarti Afaf, Bennis San |
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Genetic and epigenetic characterization of low-grade gliomas reveals frequent methylation of the MLH3 gene.
Genes, chromosomes & cancer 2015 Nov 54 (11): 655-67. Lhotska Halka, Zemanova Zuzana, Cechova Hana, Ransdorfova Sarka, Lizcova Libuse, Kramar Filip, Krejcik Zdenek, Svobodova Karla, Bystricka Dagmar, Hrabal Petr, Dohnalova Alena, Michalova Ky |
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TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas.
Oncotarget 2015 Nov . Gao Ke, Li Gang, Qu Yiping, Wang Maode, Cui Bo, Ji Meiju, Shi Bingyin, Hou Pe |
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TERT promoter mutations and rs2853669 polymorphism: prognostic impact and interactions with common alterations in glioblastomas.
Journal of neuro-oncology 2015 Nov . Nencha Umberto, Rahimian Amithys, Giry Marine, Sechi Andrea, Mokhtari Karima, Polivka Marc, Schmitt Yohann, Di Stefano Anna-Luisa, Alentorn Agusti, Labussière Marianne, Sanson Ma |
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Biomarker-based prognostic stratification of young adult glioblastoma.
Oncotarget 2015 Oct . Zhang Rui-Qi, Shi Zhifeng, Chen Hong, Chung Nellie Yuk-Fei, Yin Zi, Li Kay Ka-Wai, Chan Danny Tat-Ming, Poon Wai Sang, Wu Jinsong, Zhou Liangfu, Chan Aden Ka-Yin, Mao Ying, Ng Ho-Keu |
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Clinicopathologic implications of NF1 gene alterations in diffuse gliomas.
Human pathology 2015 Sep 46 (9): 1323-30. Vizcaíno M Adelita, Shah Smit, Eberhart Charles G, Rodriguez Fausto |
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Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.
Neuro-oncology 2015 Sep . Dubbink Hendrikus J, Atmodimedjo Peggy N, Kros Johan M, French Pim J, Sanson Marc, Idbaih Ahmed, Wesseling Pieter, Enting Roelien, Spliet Wim, Tijssen Cees, Dinjens Winand N M, Gorlia Thierry, van den Bent Martin |
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Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.
Neuro-oncology 2015 Sep 17 (9): 1231-40. Spiegl-Kreinecker Sabine, Lötsch Daniela, Ghanim Bahil, Pirker Christine, Mohr Thomas, Laaber Magdalena, Weis Serge, Olschowski Alfred, Webersinke Gerald, Pichler Josef, Berger Walt |
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Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas.
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Aug 35 (4): 324-35. Ogura Ryosuke, Tsukamoto Yoshihiro, Natsumeda Manabu, Isogawa Mizuho, Aoki Hiroshi, Kobayashi Tsutomu, Yoshida Seiichi, Okamoto Kouichiro, Takahashi Hitoshi, Fujii Yukihiko, Kakita Akiyos |
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Patterns of Tumor Contrast Enhancement Predict the Prognosis of Anaplastic Gliomas with IDH1 Mutation.
AJNR. American journal of neuroradiology 2015 Aug . Wang Y Y, Wang K, Li S W, Wang J F, Ma J, Jiang T, Dai J |
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TERT promoter mutations contribute to IDH mutations in predicting differential responses to adjuvant therapies in WHO grade II and III diffuse gliomas.
Oncotarget 2015 Jul . Zhang Zhen-Yu, Chan Aden Ka-Yin, Ding Xiao-Jie, Qin Zhi-Yong, Hong Christopher S, Chen Ling-Chao, Zhang Xin, Zhao Fang-Ping, Wang Yin, Wang Yang, Zhou Liang-Fu, Zhuang Zhengping, Ng Ho-Keung, Yan Hai, Yao Yu, Mao Yi |
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The H3.3 K27M mutation results in a poorer prognosis in brainstem gliomas than thalamic gliomas in adults.
Human pathology 2015 Jul . Feng Jie, Hao Shuyu, Pan Changcun, Wang Yu, Wu Zhen, Zhang Junting, Yan Hai, Zhang Liwei, Wan Ho |
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Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.
Acta neuropathologica 2015 May 129 (5): 669-78. Korshunov Andrey, Ryzhova Marina, Hovestadt Volker, Bender Sebastian, Sturm Dominik, Capper David, Meyer Jochen, Schrimpf Daniel, Kool Marcel, Northcott Paul A, Zheludkova Olga, Milde Till, Witt Olaf, Kulozik Andreas E, Reifenberger Guido, Jabado Nada, Perry Arie, Lichter Peter, von Deimling Andreas, Pfister Stefan M, Jones David T |
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Association between molecular alterations and tumor location and MRI characteristics in anaplastic gliomas.
Brain tumor pathology 2015 Apr 32 (2): 99-104. Sonoda Yukihiko, Shibahara Ichiyoo, Kawaguchi Tomohiro, Saito Ryuta, Kanamori Masayuki, Watanabe Mika, Suzuki Hiroyoshi, Kumabe Toshihiro, Tominaga Tei |
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CXCR7 and CXCR4 Expressions in Infiltrative Astrocytomas and Their Interactions with HIF1? Expression and IDH1 Mutation.
Pathology oncology research : POR 2015 Apr 21 (2): 229-40. Bianco Andre Macedo, Uno Miyuki, Oba-Shinjo Sueli Mieko, Clara Carlos Afonso, de Almeida Galatro Thais Fernanda, Rosemberg Sergio, Teixeira Manoel Jacobsen, Nagahashi Marie Suely Kaz |
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IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas.
Acta neuropathologica 2015 Apr 129 (4): 585-96. Olar Adriana, Wani Khalida M, Alfaro-Munoz Kristin D, Heathcock Lindsey E, van Thuijl Hinke F, Gilbert Mark R, Armstrong Terri S, Sulman Erik P, Cahill Daniel P, Vera-Bolanos Elizabeth, Yuan Ying, Reijneveld Jaap C, Ylstra Bauke, Wesseling Pieter, Aldape Kenneth |
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TERT promoter mutations and telomere length in adult malignant gliomas and recurrences.
Oncotarget 2015 Apr 6 (12): 10617-33. Heidenreich Barbara, Rachakonda P Sivaramakrishna, Hosen Ismail, Volz Florian, Hemminki Kari, Weyerbrock Astrid, Kumar Raj |
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Genetic and clinical characteristics of primary and secondary glioblastoma is associated with differential molecular subtype distribution.
Oncotarget 2015 Mar 6 (9): 7318-24. Li Rui, Li Hailin, Yan Wei, Yang Pei, Bao Zhaoshi, Zhang Chuanbao, Jiang Tao, You Yongpi |
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Anatomical localization of isocitrate dehydrogenase 1 mutation: a voxel-based radiographic study of 146 low-grade gliomas.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2015 Feb 22 (2): 348-54. Wang Y, Zhang T, Li S, Fan X, Ma J, Wang L, Jiang |
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Assessment of the Association between Isocitrate Dehydrogenase 1 Mutation and Mortality Risk of Glioblastoma Patients.
Molecular neurobiology 2015 Feb . Dai Yuting, Ning Xianbin, Han Guoqian, Li W |
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TERT promoter mutations contribute to subset prognostication of lower-grade gliomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2015 Feb 28 (2): 177-86. Chan Aden Ka-Yin, Yao Yu, Zhang Zhenyu, Chung Nellie Yuk-Fei, Liu Joseph Shu-Ming, Li Kay Ka-Wai, Shi Zhifeng, Chan Danny Tat-Ming, Poon Wai Sang, Zhou Liangfu, Ng Ho-Keu |
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ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.
Acta neuropathologica 2015 Jan 129 (1): 133-46. Reuss David E, Sahm Felix, Schrimpf Daniel, Wiestler Benedikt, Capper David, Koelsche Christian, Schweizer Leonille, Korshunov Andrey, Jones David T W, Hovestadt Volker, Mittelbronn Michel, Schittenhelm Jens, Herold-Mende Christel, Unterberg Andreas, Platten Michael, Weller Michael, Wick Wolfgang, Pfister Stefan M, von Deimling Andre |
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Evaluation of the microenvironmental heterogeneity in high-grade gliomas with IDH1/2 gene mutation using histogram analysis of diffusion-weighted imaging and dynamic-susceptibility contrast perfusion imaging.
Journal of neuro-oncology 2015 Jan 121 (1): 141-50. Lee Seunghyun, Choi Seung Hong, Ryoo Inseon, Yoon Tae Jin, Kim Tae Min, Lee Se-Hoon, Park Chul-Kee, Kim Ji-Hoon, Sohn Chul-Ho, Park Sung-Hye, Kim Il H |
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IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme.
Gene 2015 Jan 554 (1): 81-6. Kalkan Rasime, Atli Emine ?kbal, Özdemir Muhsin, Çiftçi Evrim, Aydin Hasan Emre, Artan Sevilhan, Arslanta? A |
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IDH1/2 mutation is associated with seizure as an initial symptom in low-grade glioma: A report of 311 Chinese adult glioma patients.
Epilepsy research 2015 Jan 109 100-5. Zhong Zhang, Wang Zheng, Wang Yinyan, You Gan, Jiang T |
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Expression Profile Analysis of Zinc Transporters (ZIP4, ZIP9, ZIP11, ZnT9) in Gliomas and their Correlation with IDH1 Mutation Status.
Asian Pacific journal of cancer prevention : APJCP 2015 16 (8): 3355-60. Kang Xing, Chen Rong, Zhang Jie, Li Gang, Dai Peng-Gao, Chen Chao, Wang Hui-Ju |
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IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma.
Scientific reports 2015 5 16238. Kickingereder Philipp, Sahm Felix, Radbruch Alexander, Wick Wolfgang, Heiland Sabine, Deimling Andreas von, Bendszus Martin, Wiestler Benedi |
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PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas.
PloS one 2015 10 (11): e0142750. Nakae Shunsuke, Sasaki Hikaru, Hayashi Saeko, Hattori Natsuki, Kumon Masanobu, Nishiyama Yuya, Adachi Kazuhide, Nagahisa Shinya, Hayashi Takuro, Inamasu Joji, Abe Masato, Hasegawa Mitsuhiro, Hirose Yuic |
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PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients.
Acta neuropathologica communications 2015 3 (1): 88. Draaisma Kaspar, Wijnenga Maarten M J, Weenink Bas, Gao Ya, Smid Marcel, Robe P, van den Bent Martin J, French Pim |
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TERT promoter mutated WHO grades II and III gliomas are located preferentially in the frontal lobe and avoid the midline.
International journal of clinical and experimental pathology 2015 8 (9): 11485-94. Sun Ze-Lin, Chan Aden Ka-Yin, Chen Ling-Chao, Tang Chao, Zhang Zhen-Yu, Ding Xiao-Jie, Wang Yang, Sun Chong-Ran, Ng Ho-Keung, Yao Yu, Zhou Liang- |
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Genome-wide methylation profiling identifies an essential role of reactive oxygen species in pediatric glioblastoma multiforme and validates a methylome specific for H3 histone family 3A with absence of G-CIMP/isocitrate dehydrogenase 1 mutation.
Neuro-oncology 2014 Dec 16 (12): 1607-17. Jha Prerana, Pia Patric Irene Rosita, Shukla Sudhanshu, Pathak Pankaj, Pal Jagriti, Sharma Vikas, Thinagararanjan Sivaarumugam, Santosh Vani, Suri Vaishali, Sharma Mehar Chand, Arivazhagan Arimappamagan, Suri Ashish, Gupta Deepak, Somasundaram Kumaravel, Sarkar Chit |
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Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma.
Neuro-oncology 2014 Nov 16 (11): 1478-83. Chen Li, Voronovich Zoya, Clark Kenneth, Hands Isaac, Mannas Jonathan, Walsh Meggen, Nikiforova Marina N, Durbin Eric B, Weiss Heidi, Horbinski Cra |
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[IDH1 mutation and MGMT expression in astrocytoma and the relationship with prognosis after radiotherapy].
Zhonghua bing li xue za zhi Chinese journal of pathology 2014 Oct 43 (10): 668-72. Jiang Mengwan, Dong Xianghui, Li Jiayao, Li Jingqi, Qi Jipi |
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KPNA2 predicts long term survival in patients with anaplastic oligoastrocytomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2014 Oct 21 (10): 1719-24. Gousias Konstantinos, Niehusmann Pitt, Gielen Gerrit, Simon Matthias, Boström J |
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The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma.
Journal of neuro-oncology 2014 Oct 120 (1): 85-93. Kizilbash Sani H, Giannini Caterina, Voss Jesse S, Decker Paul A, Jenkins Robert B, Hardie John, Laack Nadia N, Parney Ian F, Uhm Joon H, Buckner Jan |
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IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low-grade gliomas.
Epilepsia 2014 Sep 55 (9): 1438-43. Liubinas Simon V, D'Abaco Giovanna M, Moffat Bradford M, Gonzales Michael, Feleppa Frank, Nowell Cameron J, Gorelik Alexandra, Drummond Katharine J, O'Brien Terence J, Kaye Andrew H, Morokoff Andrew |
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The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.
Neuro-oncology 2014 Sep 16 (9): 1263-73. Molenaar Remco J, Verbaan Dagmar, Lamba Simona, Zanon Carlo, Jeuken Judith W M, Boots-Sprenger Sandra H E, Wesseling Pieter, Hulsebos Theo J M, Troost Dirk, van Tilborg Angela A, Leenstra Sieger, Vandertop W Peter, Bardelli Alberto, van Noorden Cornelis J F, Bleeker Fonnet |
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IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.
Journal of neuro-oncology 2014 Jun 118 (2): 377-83. Minniti Giuseppe, Scaringi Claudia, Arcella Antonella, Lanzetta Gaetano, Di Stefano Domenica, Scarpino Stefania, Bozzao Alessandro, Pace Andrea, Villani Veronica, Salvati Maurizio, Esposito Vincenzo, Giangaspero Felice, Enrici Riccardo Mauri |
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Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jun 20 (11): 2898-909. Wakimoto Hiroaki, Tanaka Shota, Curry William T, Loebel Franziska, Zhao Dan, Tateishi Kensuke, Chen Juxiang, Klofas Lindsay K, Lelic Nina, Kim James C, Dias-Santagata Dora, Ellisen Leif W, Borger Darrell R, Fendt Sarah-Maria, Vander Heiden Matthew G, Batchelor Tracy T, Iafrate A John, Cahill Daniel P, Chi Andrew |
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Can diffusion tensor imaging noninvasively detect IDH1 gene mutations in astrogliomas? A retrospective study of 112 cases.
AJNR. American journal of neuroradiology 2014 May 35 (5): 920-7. Tan W L, Huang W Y, Yin B, Xiong J, Wu J S, Geng D |
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Correlation of IDH1/2 mutation with clinicopathologic factors and prognosis in anaplastic gliomas: a report of 203 patients from China.
Journal of cancer research and clinical oncology 2014 Jan 140 (1): 45-51. Zhang Chuan-Bao, Bao Zhao-Shi, Wang Hong-Jun, Yan Wei, Liu Yan-Wei, Li Ming-Yang, Zhang Wei, Chen Ling, Jiang T |
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IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.
BioMed research international 2014 2014 654727. Stancheva Gergana, Goranova Teodora, Laleva Maria, Kamenova Margarita, Mitkova Atanaska, Velinov Nikolay, Poptodorov George, Mitev Vanio, Kaneva Radka, Gabrovsky Nikol |
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Isocitrate dehydrogenase-1 mutations as prognostic biomarker in glioblastoma multiforme patients in West Bohemia.
BioMed research international 2014 2014 735659. Polivka J, Polivka J, Rohan V, Pesta M, Repik T, Pitule P, Topolcan |
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