HuGE Literature Finder
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Records 1-42
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Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution.
American journal of human genetics 2017 Dec 101 (6): 925-938. Abadi Arkan, Alyass Akram, Robiou du Pont Sebastien, Bolker Ben, Singh Pardeep, Mohan Viswanathan, Diaz Rafael, Engert James C, Yusuf Salim, Gerstein Hertzel C, Anand Sonia S, Meyre Dav |
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The role of established East Asian obesity-related loci on pediatric leptin levels highlights a neuronal influence on body weight regulation in Chinese children and adolescents: the BCAMS study.
Oncotarget 2017 Nov 8 (55): 93593-93607. Fu Junling, Li Ge, Li Lujiao, Yin Jinhua, Cheng Hong, Han Lanwen, Zhang Qian, Li Naishi, Xiao Xinhua, Grant Struan F A, Li Mingyao, Gao Shan, Mi Jie, Li Mi |
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Next-generation sequencing of the monogenic obesity genes LEP, LEPR, MC4R, PCSK1 and POMC in a Norwegian cohort of patients with morbid obesity and normal weight controls.
Molecular genetics and metabolism 2017 05 121 (1): 51-56. Nordang Gry B N, Busk Øyvind L, Tveten Kristian, Hanevik Hans Ivar, Fell Anne Kristin M, Hjelmesæth Jøran, Holla Øystein L, Hertel Jens |
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Exome sequencing in Thai patients with familial obesity.
Genetics and molecular research : GMR 2016 15 (2): . Kaewsutthi S, Santiprabhob J, Phonrat B, Tungtrongchitr A, Lertrit P, Tungtrongchitr |
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Birth weight modifies the association between central nervous system gene variation and adult body mass index.
Journal of human genetics 2015 Nov . Ruiz-Narváez Edward A, Haddad Stephen A, Rosenberg Lynn, Palmer Julie |
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Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.
Human molecular genetics 2015 Jun 24 (12): 3582-94. Nead Kevin T, Li Aihua, Wehner Mackenzie R, Neupane Binod, Gustafsson Stefan, Butterworth Adam, Engert James C, Davis A Darlene, Hegele Robert A, Miller Ruby, den Hoed Marcel, Khaw Kay-Tee, Kilpeläinen Tuomas O, Wareham Nick, Edwards Todd L, Hallmans Göran, Varga Tibor V, Kardia Sharon L R, Smith Jennifer A, Zhao Wei, Faul Jessica D, Weir David, Mi Jie, Xi Bo, Quinteros Samuel Canizales, Cooper Cyrus, Sayer Avan Aihie, Jameson Karen, Grøntved Anders, Fornage Myriam, Sidney Stephen, Hanis Craig L, Highland Heather M, Häring Hans-Ulrich, Heni Martin, Lasky-Su Jessica, Weiss Scott T, Gerhard Glenn S, Still Christopher, Melka Melkaey M, Pausova Zdenka, Paus Tomáš, Grant Struan F A, Hakonarson Hakon, Price R Arlen, Wang Kai, Scherag Andre, Hebebrand Johannes, Hinney Anke, , Franks Paul W, Frayling Timothy M, McCarthy Mark I, Hirschhorn Joel N, Loos Ruth J, Ingelsson Erik, Gerstein Hertzel C, Yusuf Salim, Beyene Joseph, Anand Sonia S, Meyre Dav |
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A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity.
International journal of obesity (2005) 2015 Feb 39 (2): 295-302. Philippe J, Stijnen P, Meyre D, De Graeve F, Thuillier D, Delplanque J, Gyapay G, Sand O, Creemers J W, Froguel P, Bonnefond |
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Common variants in PCSK1 influence blood pressure and body mass index.
Journal of human hypertension 2015 Feb 29 (2): 82-6. Gu Q, Yazdanpanah M, van Hoek M, Hofman A, Gao X, de Rooij F W M, Sijbrands E J |
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Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study.
Genetics and molecular research : GMR 2015 14 (3): 9136-44. Kulanuwat S, Santiprabhob J, Phonrat B, Limwongse C, Tungtrongchitr A, Chongviriyaphan N, Tungtrongchitr |
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The association of common variants in PCSK1 with obesity: a HuGE review and meta-analysis.
American journal of epidemiology 2014 Dec 180 (11): 1051-65. Stijnen Pieter, Tuand Krizia, Varga Tibor V, Franks Paul W, Aertgeerts Bert, Creemers John W |
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[Impact of obesity-related gene polymorphism on risk of obesity and metabolic disorder in childhood].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2014 Sep 48 (9): 776-83. Zhang Meixian, Zhao Xiaoyuan, Xi Bo, Shen Yue, Wu Lijun, Cheng Hong, Hou Dongqing, Mi J |
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Association of the rs6235 variant in the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene with obesity and related traits in a Taiwanese population.
Gene 2014 Jan 533 (1): 32-7. Hsiao Tun-Jen, Hwang Yuchi, Chang Hua-Mei, Lin Euge |
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Effects of PCSK1 genetic variants on obesity among Thai children and their family members: in relation to health risk, and biochemical and anthropometric parameters.
The Southeast Asian journal of tropical medicine and public health 2014 Jan 45 (1): 214-25. Kulanuwat Sirikul, Phonrat Benjaluck, Tungtrongchitr Anchalee, Limwongse Chanin, Chongviriyaphan Nalinee, Tungtrongchitr Rungsunn, Santiprabhob Jeerun |
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Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han population.
PloS one 2014 9 (3): e91442. Zhu Jingwen, Loos Ruth J F, Lu Ling, Zong Geng, Gan Wei, Ye Xingwang, Sun Liang, Li Huaixing, Lin |
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CDKAL1-related single nucleotide polymorphisms are associated with insulin resistance in a cross-sectional cohort of Greek children.
PloS one 2014 9 (4): e93193. Rask-Andersen Mathias, Philippot Gaëtan, Moschonis George, Dedoussis George, Manios Yannis, Marcus Claude, Fredriksson Robert, Schiöth Helgi |
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An obesity genetic risk score is associated with metabolic syndrome in Chinese children.
Gene 2013 Nov . Zhao X, Xi B, Shen Y, Wu L, Hou D, Cheng H, Mi J |
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Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
Clinical endocrinology 2013 Oct 79 (4): 523-8. Xi Bo, Shen Yue, Reilly Kathleen Heather, Zhao Xiaoyuan, Cheng Hong, Hou Dongqing, Wang Xingyu, Mi J |
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Association of obesity susceptibility gene variants with metabolic syndrome and related traits in 1,443 Czech adolescents.
Folia biologica 2013 59 (3): 123-33. Dušátková L, Zamrazilová H, Sedlá?ková B, V?elák J, Hlavatý P, Aldhoon Hainerová I, Korenková V, Bradnová O, Bendlová B, Kunešová M, Hainer |
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Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.
PloS one 2013 8 (2): e57857. Choquet Hélène, Kasberger Jay, Hamidovic Ajna, Jorgenson Er |
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Individual genetic variations related to satiety and appetite control increase risk of obesity in preschool-age children in the STRONG kids program.
Human heredity 2013 75 (2-4): 152-9. Wang Yingying, Wang Anthony, Donovan Sharon M, Teran-Garcia Margarita, |
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Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children.
PloS one 2013 8 (2): e56472. Xi Bo, Cheng Hong, Shen Yue, Chandak Giriraj R, Zhao Xiaoyuan, Hou Dongqing, Wu Lijun, Wang Xingyu, Mi J |
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The obesity-related polymorphism PCSK1 rs6235 is associated with essential hypertension in the Han Chinese population.
Hypertension research : official journal of the Japanese Society of Hypertension 2012 Oct 35 (10): 994-9. Li Xiao-Mu, Ling Yan, Lu Da-Ru, Lu Zhi-Qiang, Liu Ying, Chen Hong-Yan, Gao X |
Meta-analysis identifies common variants associated with body mass index in east Asians.
Nature genetics 2012 Mar 44 (3): 307-11. Wen Wanqing, Cho Yoon-Shin, Zheng Wei, Dorajoo Rajkumar, Kato Norihiro, Qi Lu, Chen Chien-Hsiun, Delahanty Ryan J, Okada Yukinori, Tabara Yasuharu, Gu Dongfeng, Zhu Dingliang, Haiman Christopher A, Mo Zengnan, Gao Yu-Tang, Saw Seang-Mei, Go Min-Jin, Takeuchi Fumihiko, Chang Li-Ching, Kokubo Yoshihiro, Liang Jun, Hao Mei, Le Marchand Loïc, Zhang Yi, Hu Yanling, Wong Tien-Yin, Long Jirong, Han Bok-Ghee, Kubo Michiaki, Yamamoto Ken, Su Mei-Hsin, Miki Tetsuro, Henderson Brian E, Song Huaidong, Tan Aihua, He Jiang, Ng Daniel P-K, Cai Qiuyin, Tsunoda Tatsuhiko, Tsai Fuu-Jen, Iwai Naoharu, Chen Gary K, Shi Jiajun, Xu Jianfeng, Sim Xueling, Xiang Yong-Bing, Maeda Shiro, Ong Rick T H, Li Chun, Nakamura Yusuke, Aung Tin, Kamatani Naoyuki, Liu Jian-Jun, Lu Wei, Yokota Mitsuhiro, Seielstad Mark, Fann Cathy S J, , Wu Jer-Yuarn, Lee Jong-Young, Hu Frank B, Tanaka Toshihiro, Tai E Shyong, Shu Xiao- |
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Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.
Obesity (Silver Spring, Md.) 2012 Feb 20 (2): 389-95. Rouskas Konstantinos, Kouvatsi Anastasia, Paletas Konstantinos, Papazoglou Dimitrios, Tsapas Apostolos, Lobbens Stéphane, Vatin Vincent, Durand Emmanuelle, Labrune Yann, Delplanque Jérôme, Meyre David, Froguel Philip |
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Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity.
Diabetes 2012 Feb 61 (2): 383-90. Creemers John W M, Choquet Hélène, Stijnen Pieter, Vatin Vincent, Pigeyre Marie, Beckers Sigri, Meulemans Sandra, Than Manuel E, Yengo Loïc, Tauber Maithé, Balkau Beverley, Elliott Paul, Jarvelin Marjo-Riitta, Van Hul Wim, Van Gaal Luc, Horber Fritz, Pattou François, Froguel Philippe, Meyre Dav |
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PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.
PloS one 2012 7 (6): e39037. Villalobos-Comparán Marisela, Villamil-Ramírez Hugo, Villarreal-Molina Teresa, Larrieta-Carrasco Elena, León-Mimila Paola, Romero-Hidalgo Sandra, Jacobo-Albavera Leonor, Liceaga-Fuentes Adriana E, Campos-Pérez Francisco J, López-Contreras Blanca E, Tusié-Luna Teresa, Del Río-Navarro Blanca E, Aguilar-Salinas Carlos A, Canizales-Quinteros Samu |
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High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery.
Obesity (Silver Spring, Md.) 2011 Aug 19 (8): 1676-83. Still Christopher D, Wood G Craig, Chu Xin, Erdman Robert, Manney Christina H, Benotti Peter N, Petrick Anthony T, Strodel William E, Mirshahi Uyenlinh L, Mirshahi Tooraj, Carey David J, Gerhard Glenn |
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The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status.
PloS one 2011 6 (9): e23907. Gjesing Anette P, Vestmar Marie A, Jørgensen Torben, Heni Martin, Holst Jens J, Witte Daniel R, Hansen Torben, Pedersen Ol |
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A large-scale candidate gene association study of age at menarche and age at natural menopause.
Human genetics 2010 Nov 128 (5): 515-27. He Chunyan, Kraft Peter, Chasman Daniel I, Buring Julie E, Chen Constance, Hankinson Susan E, Paré Guillaume, Chanock Stephen, Ridker Paul M, Hunter David |
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Common PCSK1 haplotypes are associated with obesity in the Chinese population.
Obesity (Silver Spring, Md.) 2010 Jul 18 (7): 1404-9. Chang Yi-Cheng, Chiu Yen-Feng, Shih Kuang-Chung, Lin Ming-Wei, Sheu Wayne Huey-Herng, Donlon Timothy, Curb Jess David, Jou Yuh-Shan, Chang Tien-Jyun, Li Hung-Yuan, Chuang Lee-Mi |
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Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.
Obesity (Silver Spring, Md.) 2010 Jul 18 (7): 1369-77. Corpeleijn Eva, Petersen Liselotte, Holst Claus, Saris Wim H, Astrup Arne, Langin Dominique, MacDonald Ian, Martinez J Alfredo, Oppert Jean-Michel, Polak Jan, Pedersen Oluf, Froguel Philippe, Arner Peter, Sørensen Thorkild I A, Blaak Ellen |
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Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.
BMC medical genetics 2010 11 (1): 86. Heni Martin, Haupt Axel, Schäfer Silke A, Ketterer Caroline, Thamer Claus, Machicao Fausto, Stefan Norbert, Staiger Harald, Häring Hans-Ulrich, Fritsche Andre |
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Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.
PloS one 2010 5 (5): e10590. Qi Qibin, Li Huaixing, Loos Ruth J F, Liu Chen, Hu Frank B, Wu Hongyu, Yu Zhijie, Lin |
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Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals.
PloS one 2010 5 (12): e14190. Andersson Ehm A, Pilgaard Kasper, Pisinger Charlotta, Harder Marie N, Grarup Niels, Færch Kristine, Sandholt Camilla, Poulsen Pernille, Witte Daniel R, Jørgensen Torben, Vaag Allan, Pedersen Oluf, Hansen Torb |
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Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.
Human molecular genetics 2009 Sep 18 (18): 3496-501. Kilpeläinen Tuomas O, Bingham Sheila A, Khaw Kay-Tee, Wareham Nicholas J, Loos Ruth J |
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Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.
Human molecular genetics 2009 Apr 18 (8): 1489-96. Renström Frida, Payne Felicity, Nordström Anna, Brito Ema C, Rolandsson Olov, Hallmans Göran, Barroso Ines, Nordström Peter, Franks Paul W, |
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Common nonsynonymous variants in PCSK1 confer risk of obesity.
Nature genetics 2008 Aug 40 (8): 943-5. Benzinou Michael, Creemers John W M, Choquet Helene, Lobbens Stephane, Dina Christian, Durand Emmanuelle, Guerardel Audrey, Boutin Philippe, Jouret Beatrice, Heude Barbara, Balkau Beverley, Tichet Jean, Marre Michel, Potoczna Natascha, Horber Fritz, Le Stunff Catherine, Czernichow Sebastien, Sandbaek Annelli, Lauritzen Torsten, Borch-Johnsen Knut, Andersen Gitte, Kiess Wieland, Körner Antje, Kovacs Peter, Jacobson Peter, Carlsson Lena M S, Walley Andrew J, Jørgensen Torben, Hansen Torben, Pedersen Oluf, Meyre David, Froguel Philip |
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PC-1 genotype and IRS response to exercise training.
International journal of sports medicine 2008 Apr 29 (4): 294-9. Park S, Han T, Son T, Kang H |
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Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study.
Diabetologia 2004 May 47 (5): 871-7. Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle T T, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, |
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The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth.
The Journal of clinical endocrinology and metabolism 2004 May 89 (5): 2044-7. Kubaszek Agata, Markkanen Anu, Eriksson Johan G, Forsen Tom, Osmond Clive, Barker David J P, Laakso Mark |
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The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance.
The Journal of clinical endocrinology and metabolism 2001 Dec 86 (12): 5888-91. Frittitta L, Baratta R, Spampinato D, Di Paola R, Pizzuti A, Vigneri R, Trischitta |
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Frequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 0 9 (3): 436-41. Parikh Manish, Hetherington Jessica, Sheth Sheetal, Seiler Jamie, Ostrer Harry, Gerhard Glenn, Wood Craig, Still Christoph |
- Page last reviewed:Jul 30, 2019
- Page last updated:Aug 15, 2019
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