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| Interleukine-1 receptor like-1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age. Acta paediatrica (Oslo, Norway : 1992) 2021 Nov . Riikonen Riikka, Teräsjärvi Johanna, Lauhkonen Eero, Nuolivirta Kirsi, He Qiushui, Korppi Mat |
| Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI insight 2020 Apr 5 (8): . Portelli Michael A, Dijk F Nicole, Ketelaar Maria E, Shrine Nick, Hankinson Jenny, Bhaker Sangita, Grotenboer Néomi S, Obeidat Ma'en, Henry Amanda P, Billington Charlotte K, Shaw Dominick, Johnson Simon R, Pogson Zara Ek, Fogarty Andrew, McKeever Tricia M, Nickle David C, Bossé Yohan, van den Berge Maarten, Faiz Alen, Brouwer Sharon, Vonk Judith M, de Vos Paul, Brandsma Corry-Anke, Vermeulen Cornelis J, Singapuri Amisha, Heaney Liam G, Mansur Adel H, Chaudhuri Rekha, Thomson Neil C, Holloway John W, Lockett Gabrielle A, Howarth Peter H, Niven Robert, Simpson Angela, Blakey John D, Tobin Martin D, Postma Dirkje S, Hall Ian P, Wain Louise V, Nawijn Martijn C, Brightling Christopher E, Koppelman Gerard H, Sayers I |
| Association of IL1RL1 rs3771180 and TSLP rs1837253 variants with asthma in the Guangxi Zhuang population in China. Journal of clinical laboratory analysis 2019 May e22905. Sun Yan, Wei Xuan, Deng Jingmin, Zhang Jianquan, He Zhiyi, Yang Meiling, Liang Siqiao, Chen Zhangrong, Qin Huaji |
| Serum IL-33 Level and IL-33, IL1RL1 Gene Polymorphisms in Asthma and Multiple Sclerosis Patients. Current molecular medicine 2019 Apr . Ahmadi Maryam, Fathi Farshid, Fouladi Saloomeh, Alsahebfosul Fereshteh, Manian Mostafa, Eskandari Nah |
Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.
Respiratory research 2018 Oct 19 (1): 209. Hayden Lystra P, Cho Michael H, Raby Benjamin A, Beaty Terri H, Silverman Edwin K, Hersh Craig P, |
| Novel genes and insights in complete asthma remission: A genome-wide association study on clinical and complete asthma remission.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2018 May . Vonk Judith M, Nieuwenhuis Maartje A E, Dijk F Nicole, Boudier Anne, Siroux Valerie, Bouzigon Emmanuelle, Probst-Hensch Nicole, Imboden Medea, Keidel Dirk, Sin Don, Bossé Yohan, Hao Ke, van den Berge Maarten, Faiz Alen, Koppelman Gerard H, Postma Dirkje |
| Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma. The European respiratory journal 2018 Mar 51 (3): . Dijk F Nicole, Xu Chengjian, Melén Erik, Carsin Anne-Elie, Kumar Asish, Nolte Ilja M, Gruzieva Olena, Pershagen Goran, Grotenboer Neomi S, Savenije Olga E M, Antó Josep Maria, Lavi Iris, Dobaño Carlota, Bousquet Jean, van der Vlies Pieter, van der Valk Ralf J P, de Jongste Johan C, Nawijn Martijn C, Guerra Stefano, Postma Dirkje S, Koppelman Gerard |
| Association of interleukin 1 receptor-like 1 gene polymorphisms with eosinophilic phenotype in Japanese adults with asthma. Respiratory investigation 2017 Nov 55 (6): 338-347. Inoue Hideki, Ito Isao, Niimi Akio, Matsumoto Hisako, Oguma Tsuyoshi, Tajiri Tomoko, Iwata Toshiyuki, Nagasaki Tadao, Kanemitsu Yoshihiro, Morishima Toshitaka, Hirota Tomomitsu, Tamari Mayumi, Wenzel Sally E, Mishima Michia |
| A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.
The European respiratory journal 2017 May 49 (5): . Yan Qi, Brehm John, Pino-Yanes Maria, Forno Erick, Lin Jerome, Oh Sam S, Acosta-Perez Edna, Laurie Cathy C, Cloutier Michelle M, Raby Benjamin A, Stilp Adrienne M, Sofer Tamar, Hu Donglei, Huntsman Scott, Eng Celeste S, Conomos Matthew P, Rastogi Deepa, Rice Kenneth, Canino Glorisa, Chen Wei, Barr R Graham, Burchard Esteban G, Celedón Juan |
| IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population. International journal of immunogenetics 2017 Apr 44 (2): 51-61. Queiroz G A, Costa R S, Alcantara-Neves N M, Nunes de Oliveira Costa G, Barreto M L, Carneiro V L, Figueiredo C |
| A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma. PLoS genetics 2017 Mar 13 (3): e1006659. Smith Dirk, Helgason Hannes, Sulem Patrick, Bjornsdottir Unnur Steina, Lim Ai Ching, Sveinbjornsson Gardar, Hasegawa Haruki, Brown Michael, Ketchem Randal R, Gavala Monica, Garrett Logan, Jonasdottir Adalbjorg, Jonasdottir Aslaug, Sigurdsson Asgeir, Magnusson Olafur T, Eyjolfsson Gudmundur I, Olafsson Isleifur, Onundarson Pall Torfi, Sigurdardottir Olof, Gislason David, Gislason Thorarinn, Ludviksson Bjorn Runar, Ludviksottir Dora, Boezen H Marike, Heinzmann Andrea, Krueger Marcus, Porsbjerg Celeste, Ahluwalia Tarunveer S, Waage Johannes, Backer Vibeke, Deichmann Klaus A, Koppelman Gerard H, Bønnelykke Klaus, Bisgaard Hans, Masson Gisli, Thorsteinsdottir Unnur, Gudbjartsson Daniel F, Johnston James A, Jonsdottir Ingileif, Stefansson Ka |
| IL1RL1 asthma risk variants regulate airway type 2 inflammation. JCI insight 2016 Sep 1 (14): e87871. Gordon Erin D, Palandra Joe, Wesolowska-Andersen Agata, Ringel Lando, Rios Cydney L, Lachowicz-Scroggins Marrah E, Sharp Louis Z, Everman Jamie L, MacLeod Hannah J, Lee Jae W, Mason Robert J, Matthay Michael A, Sheldon Richard T, Peters Michael C, Nocka Karl H, Fahy John V, Seibold Max |
| IL-33 polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2016 May . Schröder Paul Christoph, Casaca Vera Isabel, Illi Sabina, Schieck Maximilian, Michel Sven, Böck Andreas, Roduit Caroline, Frei Remo, Lluis Anna, Genuneit Jon, Pfefferle Petra, Roponen Marjut, Weber Juliane, Braun-Fahrländer Charlotte, Riedler Josef, Lauener Roger, Vuitton Dominique Angèle, Dalphin Jean-Charles, Pekkanen Juha, von Mutius Erika, Kabesch Michael, Schaub Bianca, |
| Asthma susceptibility variants are more strongly associated with clinically similar subgroups. The Journal of asthma : official journal of the Association for the Care of Asthma 2016 Apr 0. Lavoie-Charland Emilie, Bérubé Jean-Christophe, Boulet Louis-Philippe, Bossé Yoh |
| Identification of a new locus at 16q12 associated with time to asthma onset.
The Journal of allergy and clinical immunology 2016 Apr . Sarnowski Chloé, Sugier Pierre-Emmanuel, Granell Raquel, Jarvis Debbie, Dizier Marie-Hélène, Ege Markus, Imboden Medea, Laprise Catherine, Khusnutdinova Elza K, Freidin Maxim B, Cookson William O C, Moffatt Miriam, Lathrop Mark, Siroux Valérie, Ogorodova Ludmila M, Karunas Alexandra S, James Alan, Probst-Hensch Nicole M, von Mutius Erika, Pin Isabelle, Kogevinas Manolis, Henderson A John, Demenais Florence, Bouzigon Emmanuel |
| Heritability and confirmation of genetic association studies for childhood asthma in twins. Allergy 2016 Feb 71 (2): 230-8. Ullemar V, Magnusson P K E, Lundholm C, Zettergren A, Melén E, Lichtenstein P, Almqvist |
| Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma. The Journal of allergy and clinical immunology 2015 Jan 135 (1): 92-9. Traister Russell S, Uvalle Crystal E, Hawkins Gregory A, Meyers Deborah A, Bleecker Eugene R, Wenzel Sally |
| Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood. The Journal of allergy and clinical immunology 2014 Jul 134 (1): 170-7. Savenije Olga E, Mahachie John Jestinah M, Granell Raquel, Kerkhof Marjan, Dijk F Nicole, de Jongste Johan C, Smit Henriëtte A, Brunekreef Bert, Postma Dirkje S, Van Steen Kristel, Henderson John, Koppelman Gerard |
| A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Nature genetics 2014 Jan 46 (1): 51-5. Bønnelykke Klaus, Sleiman Patrick, Nielsen Kasper, Kreiner-Møller Eskil, Mercader Josep M, Belgrave Danielle, den Dekker Herman T, Husby Anders, Sevelsted Astrid, Faura-Tellez Grissel, Mortensen Li Juel, Paternoster Lavinia, Flaaten Richard, Mølgaard Anne, Smart David E, Thomsen Philip F, Rasmussen Morten A, Bonàs-Guarch Silvia, Holst Claus, Nohr Ellen A, Yadav Rachita, March Michael E, Blicher Thomas, Lackie Peter M, Jaddoe Vincent W V, Simpson Angela, Holloway John W, Duijts Liesbeth, Custovic Adnan, Davies Donna E, Torrents David, Gupta Ramneek, Hollegaard Mads V, Hougaard David M, Hakonarson Hakon, Bisgaard Ha |
| Replication and fine mapping of asthma-associated loci in individuals of African ancestry. Human genetics 2013 Sep 132 (9): 1039-47. Kantor David B, Palmer Cameron D, Young Taylor R, Meng Yan, Gajdos Zofia K, Lyon Helen, Price Alkes L, Pollack Samuela, London Stephanie J, Loehr Laura R, Smith Lewis J, Kumar Rajesh, Jacobs David R, Petrini Marcy F, O'Connor George T, White Wendy B, Papanicolaou George, Burkart Kristin M, Heckbert Susan R, Barr R Graham, Hirschhorn Joel |
| Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
The Journal of allergy and clinical immunology 2013 Aug 132 (2): 313-20.e15. Li Xingnan, Hawkins Gregory A, Ampleford Elizabeth J, Moore Wendy C, Li Huashi, Hastie Annette T, Howard Timothy D, Boushey Homer A, Busse William W, Calhoun William J, Castro Mario, Erzurum Serpil C, Israel Elliot, Lemanske Robert F, Szefler Stanley J, Wasserman Stephen I, Wenzel Sally E, Peters Stephen P, Meyers Deborah A, Bleecker Eugene |
| Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children. BMC medical genetics 2013 14 100. Tulah Asif S, Holloway John W, Sayers I |
| Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
PloS one 2012 7 (9): 9. Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon HN, Ferreira MA, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin L, Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kähönen M, Khaw KT, Laitinen J, Le Souef P, Lehtimäki T, Madden PA, Marks GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A, Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW, Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T, Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR, Hirschhorn JN |
| Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. The Journal of allergy and clinical immunology 2012 Oct 130 (4): 861-8.e7. Li Xingnan, Ampleford Elizabeth J, Howard Timothy D, Moore Wendy C, Torgerson Dara G, Li Huashi, Busse William W, Castro Mario, Erzurum Serpil C, Israel Elliot, Nicolae Dan L, Ober Carole, Wenzel Sally E, Hawkins Gregory A, Bleecker Eugene R, Meyers Deborah |
| Genome-wide association study to identify genetic determinants of severe asthma.
Thorax 2012 May . Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP |
| Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Nature genetics 2011 Sep 43 (9): 887-92. Torgerson Dara G, Ampleford Elizabeth J, Chiu Grace Y, Gauderman W James, Gignoux Christopher R, Graves Penelope E, Himes Blanca E, Levin Albert M, Mathias Rasika A, Hancock Dana B, Baurley James W, Eng Celeste, Stern Debra A, Celedón Juan C, Rafaels Nicholas, Capurso Daniel, Conti David V, Roth Lindsey A, Soto-Quiros Manuel, Togias Alkis, Li Xingnan, Myers Rachel A, Romieu Isabelle, Van Den Berg David J, Hu Donglei, Hansel Nadia N, Hernandez Ryan D, Israel Elliott, Salam Muhammad T, Galanter Joshua, Avila Pedro C, Avila Lydiana, Rodriquez-Santana Jose R, Chapela Rocio, Rodriguez-Cintron William, Diette Gregory B, Adkinson N Franklin, Abel Rebekah A, Ross Kevin D, Shi Min, Faruque Mezbah U, Dunston Georgia M, Watson Harold R, Mantese Vito J, Ezurum Serpil C, Liang Liming, Ruczinski Ingo, Ford Jean G, Huntsman Scott, Chung Kian Fan, Vora Hita, Li Xia, Calhoun William J, Castro Mario, Sienra-Monge Juan J, del Rio-Navarro Blanca, Deichmann Klaus A, Heinzmann Andrea, Wenzel Sally E, Busse William W, Gern James E, Lemanske Robert F, Beaty Terri H, Bleecker Eugene R, Raby Benjamin A, Meyers Deborah A, London Stephanie J, , Gilliland Frank D, , Burchard Esteban G, , Martinez Fernando D, , Weiss Scott T, , Williams L Keoki, , Barnes Kathleen C, , Ober Carole, Nicolae Dan |
| Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
European journal of human genetics : EJHG 2011 Apr 19 (4): 458-64. Ferreira Manuel A R, McRae Allan F, Medland Sarah E, Nyholt Dale R, Gordon Scott D, Wright Margaret J, Henders Anjali K, Madden Pamela A, Visscher Peter M, Wray Naomi R, Heath Andrew C, Montgomery Grant W, Duffy David L, Martin Nicholas |
| Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. The Journal of allergy and clinical immunology 2011 Mar 127 (3): 750-6.e1-5. Savenije Olga E M, Kerkhof Marjan, Reijmerink Naomi E, Brunekreef Bert, de Jongste Johan C, Smit Henriëtte A, Wijga Alet H, Postma Dirkje S, Koppelman Gerard |
| A large-scale, consortium-based genomewide association study of asthma.
The New England journal of medicine 2010 Sep 363 (13): 1211-21. Moffatt Miriam F, Gut Ivo G, Demenais Florence, Strachan David P, Bouzigon Emmanuelle, Heath Simon, von Mutius Erika, Farrall Martin, Lathrop Mark, Cookson William O C M, |
| Analyses of shared genetic factors between asthma and obesity in children. The Journal of allergy and clinical immunology 2010 Sep 126 (3): 631-7.e1-8. Melén Erik, Himes Blanca E, Brehm John M, Boutaoui Nadia, Klanderman Barbara J, Sylvia Jody S, Lasky-Su Jessi |
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