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Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Nature genetics 2018 Jul . Nielsen Jonas B, Thorolfsdottir Rosa B, Fritsche Lars G, Zhou Wei, Skov Morten W, Graham Sarah E, Herron Todd J, McCarthy Shane, Schmidt Ellen M, Sveinbjornsson Gardar, Surakka Ida, Mathis Michael R, Yamazaki Masatoshi, Crawford Ryan D, Gabrielsen Maiken E, Skogholt Anne Heidi, Holmen Oddgeir L, Lin Maoxuan, Wolford Brooke N, Dey Rounak, Dalen Håvard, Sulem Patrick, Chung Jonathan H, Backman Joshua D, Arnar David O, Thorsteinsdottir Unnur, Baras Aris, O'Dushlaine Colm, Holst Anders G, Wen Xiaoquan, Hornsby Whitney, Dewey Frederick E, Boehnke Michael, Kheterpal Sachin, Mukherjee Bhramar, Lee Seunggeun, Kang Hyun M, Holm Hilma, Kitzman Jacob, Shavit Jordan A, Jalife José, Brummett Chad M, Teslovich Tanya M, Carey David J, Gudbjartsson Daniel F, Stefansson Kari, Abecasis Gonçalo R, Hveem Kristian, Willer Cristen |
| Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation. Scientific reports 2018 Feb 8 (1): 3297. Wang Pengxia, Qin Weixi, Wang Pengyun, Huang Yufeng, Liu Ying, Zhang Rongfeng, Li Sisi, Yang Qin, Wang Xiaojing, Chen Feifei, Liu Jingqiu, Yang Bo, Cheng Xiang, Liao Yuhua, Wu Yanxia, Ke Tie, Tu Xin, Ren Xiang, Yang Yanzong, Xia Yunlong, Luo Xiaoping, Liu Mugen, Li He, Liu Jingyu, Xiao Yi, Chen Qiuyun, Xu Chengqi, Wang Qing |
| TBX5 loss-of-function mutation contributes to atrial fibrillation and atypical Holt-Oram syndrome. Molecular medicine reports 2016 Mar . Guo Dong-Feng, Li Ruo-Gu, Yuan Fang, Shi Hong-Yu, Hou Xu-Min, Qu Xin-Kai, Xu Ying-Jia, Zhang Min, Liu Xu, Jiang Jin-Qi, Yang Yi-Qing, Qiu Xing-Bi |
| TBX5 mutations contribute to early-onset atrial fibrillation in Chinese and Caucasians. Cardiovascular research 2016 Jan . Ma Ji-Fang, Yang Fan, Mahida Saagar N, Zhao Ling, Chen Xiaomin, Zhang Michael L, Sun Zhijun, Yao Yan, Zhang Yi-Xin, Zheng Gu-Yan, Dong Jie, Feng Ming-Jun, Zhang Rui, Sun Jian, Li Shuo, Wang Qun-Shan, Cao Huiqing, Benjamin Emelia J, Ellinor Patrick T, Li Yi-Gang, Tian Xiao- |
| Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation. PLoS genetics 2015 Aug 11 (8): e1005393. Huang Yufeng, Wang Chuchu, Yao Yufeng, Zuo Xiaoyu, Chen Shanshan, Xu Chengqi, Zhang Hongfu, Lu Qiulun, Chang Le, Wang Fan, Wang Pengxia, Zhang Rongfeng, Hu Zhenkun, Song Qixue, Yang Xiaowei, Li Cong, Li Sisi, Zhao Yuanyuan, Yang Qin, Yin Dan, Wang Xiaojing, Si Wenxia, Li Xiuchun, Xiong Xin, Wang Dan, Huang Yuan, Luo Chunyan, Li Jia, Wang Jingjing, Chen Jing, Wang Longfei, Wang Li, Han Meng, Ye Jian, Chen Feifei, Liu Jingqiu, Liu Ying, Wu Gang, Yang Bo, Cheng Xiang, Liao Yuhua, Wu Yanxia, Ke Tie, Chen Qiuyun, Tu Xin, Elston Robert, Rao Shaoqi, Yang Yanzong, Xia Yunlong, Wang Qing |
| Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation 2014 Oct 130 (15): 1225-35. Sinner Moritz F, Tucker Nathan R, Lunetta Kathryn L, Ozaki Kouichi, Smith J Gustav, Trompet Stella, Bis Joshua C, Lin Honghuang, Chung Mina K, Nielsen Jonas B, Lubitz Steven A, Krijthe Bouwe P, Magnani Jared W, Ye Jiangchuan, Gollob Michael H, Tsunoda Tatsuhiko, Müller-Nurasyid Martina, Lichtner Peter, Peters Annette, Dolmatova Elena, Kubo Michiaki, Smith Jonathan D, Psaty Bruce M, Smith Nicholas L, Jukema J Wouter, Chasman Daniel I, Albert Christine M, Ebana Yusuke, Furukawa Tetsushi, Macfarlane Peter W, Harris Tamara B, Darbar Dawood, Dörr Marcus, Holst Anders G, Svendsen Jesper H, Hofman Albert, Uitterlinden Andre G, Gudnason Vilmundur, Isobe Mitsuaki, Malik Rainer, Dichgans Martin, Rosand Jonathan, Van Wagoner David R, , , Benjamin Emelia J, Milan David J, Melander Olle, Heckbert Susan R, Ford Ian, Liu Yongmei, Barnard John, Olesen Morten S, Stricker Bruno H C, Tanaka Toshihiro, Kääb Stefan, Ellinor Patrick |
| SNP rs3825214 in TBX5 is associated with lone atrial fibrillation in Chinese Han population. PloS one 2013 8 (5): e64966. Zang Xiaobiao, Zhang Shulong, Xia Yunlong, Li Sisi, Fu Fenfen, Li Xiuchun, Wang Fan, Zhang Rongfeng, Tian Xiaochen, Gao Lianjun, Zhang Jiaying, Yang Yanzong, Tu Xin, Wang Qi |
| Genome-wide association studies of the PR interval in African Americans.
PLoS genetics 2011 7 (2): e1001304. Smith J Gustav, Magnani Jared W, Palmer Cameron, Meng Yan A, Soliman Elsayed Z, Musani Solomon K, Kerr Kathleen F, Schnabel Renate B, Lubitz Steven A, Sotoodehnia Nona, Redline Susan, Pfeufer Arne, Müller Martina, Evans Daniel S, Nalls Michael A, Liu Yongmei, Newman Anne B, Zonderman Alan B, Evans Michele K, Deo Rajat, Ellinor Patrick T, Paltoo Dina N, Newton-Cheh Christopher, Benjamin Emelia J, Mehra Reena, Alonso Alvaro, Heckbert Susan R, Fox Ervin R, |
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