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| Association of Apolipoprotein E ?4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome. JAMA neurology 2021 Jul . Bejanin Alexandre, Iulita Maria Florencia, Vilaplana Eduard, Carmona-Iragui Maria, Benejam Bessy, Videla Laura, Barroeta Isabel, Fernandez Susana, Altuna Miren, Pegueroles Jordi, Montal Victor, Valldeneu Silvia, Giménez Sandra, González-Ortiz Sofía, Muñoz Laia, Padilla Concepción, Aranha Mateus Rozalem, Estellés Teresa, Illán-Gala Ignacio, Belbin Olivia, Camacho Valle, Wilson Liam Reese, Annus Tiina, Osorio Ricardo S, Videla Sebastián, Lehmann Sylvain, Holland Anthony J, Zetterberg Henrik, Blennow Kaj, Alcolea Daniel, Clarimon Jordi, Zaman Shahid H, Blesa Rafael, Lleó Alberto, Fortea Ju |
| Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging. JAMA neurology 2021 Jun . Ossenkoppele Rik, Smith Ruben, Mattsson-Carlgren Niklas, Groot Colin, Leuzy Antoine, Strandberg Olof, Palmqvist Sebastian, Olsson Tomas, Jögi Jonas, Stormrud Erik, Cho Hanna, Ryu Young Hoon, Choi Jae Yong, Boxer Adam L, Gorno-Tempini Maria L, Miller Bruce L, Soleimani-Meigooni David, Iaccarino Leonardo, La Joie Renaud, Baker Suzanne, Borroni Edilio, Klein Gregory, Pontecorvo Michael J, Devous Michael D, Jagust William J, Lyoo Chul Hyoung, Rabinovici Gil D, Hansson Osk |
| Association of APOE e4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study. PLoS medicine 2021 Jun 18 (6): e1003597. Jin Xurui, He Wanying, Zhang Yan, Gong Enying, Niu Zhangming, Ji John, Li Yaxi, Zeng Yi, Yan Lijing |
| Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. Molecular psychiatry 2021 Jun . DeMichele-Sweet Mary Ann A, Klei Lambertus, Creese Byron, Harwood Janet C, Weamer Elise A, McClain Lora, Sims Rebecca, Hernandez Isabel, Moreno-Grau Sonia, Tárraga Lluís, Boada Mercè, Alarcón-Martín Emilio, Valero Sergi, , Liu Yushi, Hooli Basavaraj, Aarsland Dag, Selbaek Geir, Bergh Sverre, Rongve Arvid, Saltvedt Ingvild, Skjellegrind Håvard K, Engdahl Bo, Stordal Eystein, Andreassen Ole A, Djurovic Srdjan, Athanasiu Lavinia, Seripa Davide, Borroni Barbara, Albani Diego, Forloni Gianluigi, Mecocci Patrizia, Serretti Alessandro, De Ronchi Diana, Politis Antonis, Williams Julie, Mayeux Richard, Foroud Tatiana, Ruiz Agustin, Ballard Clive, Holmans Peter, Lopez Oscar L, Kamboh M Ilyas, Devlin Bernie, Sweet Robert |
| Protective Effects of APOE e2 Genotype on Cognition in Older Breast Cancer Survivors: The Thinking and Living With Cancer Study. JNCI cancer spectrum 2021 Apr 5 (2): pkab013. Van Dyk Kathleen, Zhou Xingtao, Small Brent J, Ahn Jaeil, Zhai Wanting, Ahles Tim, Graham Deena, Jacobsen Paul B, Jim Heather, McDonald Brenna C, Nudelman Holohan Kelly, Patel Sunita K, Rebeck G William, Root James C, Saykin Andrew J, Cohen Harvey Jay, Mandelblatt Jeanne S, Carroll Judith |
| DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease. The American journal of clinical nutrition 2021 Mar . Sala-Vila Aleix, Arenaza-Urquijo Eider M, Sánchez-Benavides Gonzalo, Suárez-Calvet Marc, Milà-Alomà Marta, Grau-Rivera Oriol, González-de-Echávarri José M, Crous-Bou Marta, Minguillón Carolina, Fauria Karine, Operto Grégory, Falcón Carles, Salvadó Gemma, Cacciaglia Raffaele, Ingala Silvia, Barkhof Frederik, Schröder Helmut, Scarmeas Nikolaos, Gispert Juan-Domingo, Molinuevo José L, |
| Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease. Neurology 2021 Jan . Joseph-Mathurin Nelly, Wang Guoqiao, Kantarci Kejal, Jack Clifford R, McDade Eric, Hassenstab Jason, Blazey Tyler M, Gordon Brian A, Su Yi, Chen Gengsheng, Massoumzadeh Parinaz, Hornbeck Russ C, Allegri Ricardo F, Ances Beau M, Berman Sarah B, Brickman Adam M, Brooks William S, Cash David M, Chhatwal Jasmeer P, Chui Helena C, Correia Stephen, Cruchaga Carlos, Farlow Martin R, Fox Nick C, Fulham Michael, Ghetti Bernardino, Graff-Radford Neill R, Johnson Keith A, Karch Celeste M, Laske Christoph, Lee Athene K W, Levin Johannes, Masters Colin L, Noble James M, O'Connor Antoinette, Perrin Richard J, Preboske Gregory M, Ringman John M, Rowe Christopher C, Salloway Stephen, Saykin Andrew J, Schofield Peter R, Shimada Hiroyuki, Shoji Mikio, Suzuki Kazushi, Villemagne Victor L, Xiong Chengjie, Yakushev Igor, Morris John C, Bateman Randall J, Benzinger Tammie L S, |
| APOE-e4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease. Frontiers in neuroscience 2021 15 619051. Hou Min, Xu Gaolian, Ran Maosheng, Luo Wei, Wang H |
| Dissecting the role of Amerindian genetic ancestry and the ApoE e4 allele on Alzheimer disease in an admixed Peruvian population. Neurobiology of aging 2020 Dec . Marca-Ysabel Maria Victoria, Rajabli Farid, Cornejo-Olivas Mario, Whitehead Patrice G, Hofmann Natalia K, Illanes Manrique Maryenela Zaida, Veliz Otani Diego Martin, Milla Neyra Ana Karina, Castro Suarez Sheila, Meza Vega Maria, Adams Larry D, Mena Pedro R, Rosario Isasi, Cuccaro Michael L, Vance Jeffery M, Beecham Gary W, Custodio Nilton, Montesinos Rosa, Mazzetti Soler Pilar E, Pericak-Vance Margaret |
| APOE Genotype Disclosure and Lifestyle Advice in a Randomized Intervention Study with Finnish Participants. The Journal of nutrition 2020 Nov . Leskinen Heidi M, Tringham Maaria, Karjalainen Heli, Iso-Touru Terhi K, Hietaranta-Luoma Hanna-Leena, Marnila Pertti J, Pihlava Juha-Matti, Hurme Timo, Kankaanpää Santeri J, Puolijoki Hannu, Åkerman Kari, Tanner Laura, Sandell Mari, Vähäkangas Kirsi, Hopia Anu, Tahvonen Raija, Rokka L Susan |
| APOE Genotypes and Brain Imaging Classes in Normal Cognition, Mild Cognitive Impairment, and Alzheimer's Disease: A Longitudinal Study. Current Alzheimer research 2020 Nov . Camarda Cecilia, Torelli Paola, Pipia Carmela, Sottile Gianluca, Cilluffo Giovanna, Camarda Rosoli |
| Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry. JAMA network open 2020 Oct 3 (10): e2017666. Blue Elizabeth E, Cheng Anqi, Chen Sunny, Yu Chang-En, |
| Association between APOE e2 and Aß burden in patients with Alzheimer- and vascular-type cognitive impairment. Neurology 2020 Sep . San Lee Jin, Lee Hyejoo, Park Seongbeom, Choe Yeongsim, Park Yu Hyun, Cheon Bo Kyoung, Hahn Alice, Ossenkoppele Rik, Kim Hee Jin, Kim Seonwoo, Yoo Heejin, Jang Hyemin, Cho Soo Hyun, Kim Seung Joo, Kim Jun Pyo, Jung Young Hee, Park Key-Chung, DeCarli Charles, Weiner Michael W, Na Duk L, Seo Sang W |
| Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. PLoS medicine 2020 Aug 17 (8): e1003289. Saddiki Hana, Fayosse Aurore, Cognat Emmanuel, Sabia Séverine, Engelborghs Sebastiaan, Wallon David, Alexopoulos Panagiotis, Blennow Kaj, Zetterberg Henrik, Parnetti Lucilla, Zerr Inga, Hermann Peter, Gabelle Audrey, Boada Mercè, Orellana Adelina, de Rojas Itziar, Lilamand Matthieu, Bjerke Maria, Van Broeckhoven Christine, Farotti Lucia, Salvadori Nicola, Diehl-Schmid Janine, Grimmer Timo, Hourregue Claire, Dugravot Aline, Nicolas Gaël, Laplanche Jean-Louis, Lehmann Sylvain, Bouaziz-Amar Elodie, , Hugon Jacques, Tzourio Christophe, Singh-Manoux Archana, Paquet Claire, Dumurgier Juli |
| Sex differences in CSF biomarkers vary by Alzheimer disease stage and APOE e4 genotype. Neurology 2020 Aug . Mofrad Rosha Babapour, Tijms Betty M, Scheltens Philip, Barkhof Frederik, van der Flier Wiesje M, Am Sikkes Sietske, Teunissen Charlotte |
| An Ig ? Marker Genotype Is a Strong Risk Factor for Alzheimer Disease, Independent of Apolipoprotein E e4 Genotype. Journal of immunology (Baltimore, Md. : 1950) 2020 Jul . Pandey Janardan P, Olsson Jan, Weidung Bodil, Kothera Ronald T, Johansson Anders, Eriksson Sture, Hallmans Göran, Elgh Fredrik, Lövheim Hu |
| Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE e4. Investigative ophthalmology & visual science 2020 Jul 61 (8): 3. Margeta Milica A, Letcher Sophia M, Igo Robert P, Cooke Bailey Jessica N, Pasquale Louis R, Haines Jonathan L, Butovsky Oleg, Wiggs Janey L, |
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
JAMA neurology 2020 Jun . Raghavan Neha S, Dumitrescu Logan, Mormino Elizabeth, Mahoney Emily R, Lee Annie J, Gao Yizhe, Bilgel Murat, Goldstein David, Harrison Theresa, Engelman Corinne D, Saykin Andrew J, Whelan Christopher D, Liu Jimmy Z, Jagust William, Albert Marilyn, Johnson Sterling C, Yang Hyun-Sik, Johnson Keith, Aisen Paul, Resnick Susan M, Sperling Reisa, De Jager Philip L, Schneider Julie, Bennett David A, Schrag Matthew, Vardarajan Badri, Hohman Timothy J, Mayeux Richard, |
| Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4. JAMA neurology 2020 Apr . Belloy Michael E, Napolioni Valerio, Han Summer S, Le Guen Yann, Greicius Michael D, |
| Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E e4 genotype. Scientific reports 2020 Feb 10 (1): 2924. Friedberg Jacob S, Aytan Nurgul, Cherry Jonathan D, Xia Weiming, Standring Oliver J, Alvarez Victor E, Nicks Raymond, Svirsky Sarah, Meng Gaoyuan, Jun Gyungah, Ryu Hoon, Au Rhoda, Stein Thor |
| Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects. Neuro-degenerative diseases 2019 Dec 1-9. Haller Sven, Montandon Marie-Louise, Rodriguez Cristelle, Garibotto Valentina, Herrmann François R, Giannakopoulos Panteleim |
| Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD. Journal of neuropathology and experimental neurology 2019 Dec . Robinson John L, Yan Ning, Caswell Carrie, Xie Sharon X, Suh EunRan, Van Deerlin Vivianna M, Gibbons Garrett, Irwin David J, Grossman Murray, Lee Edward B, Lee Virginia M-Y, Miller Bruce, Trojanowski John |
| Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. JAMA neurology 2019 Jun . Ma Yiyi, Jun Gyungah R, Zhang Xiaoling, Chung Jaeyoon, Naj Adam C, Chen Yuning, Bellenguez Celine, Hamilton-Nelson Kara, Martin Eden R, Kunkle Brian W, Bis Joshua C, Debette Stéphanie, DeStefano Anita L, Fornage Myriam, Nicolas Gaël, van Duijn Cornelia, Bennett David A, De Jager Philip L, Mayeux Richard, Haines Jonathan L, Pericak-Vance Margaret A, Seshadri Sudha, Lambert Jean-Charles, Schellenberg Gerard D, Lunetta Kathryn L, Farrer Lindsay A, |
| Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB. JAMA neurology 2019 May . Wingo Thomas S, Cutler David J, Wingo Aliza P, Le Ngoc-Anh, Rabinovici Gil D, Miller Bruce L, Lah James J, Levey Allan |
| CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging cell 2019 May e12964. Ma Yiyi, Jun Gyungah R, Chung Jaeyoon, Zhang Xiaoling, Kunkle Brian W, Naj Adam C, White Charles C, Bennett David A, De Jager Philip L, , Mayeux Richard, Haines Jonathan L, Pericak-Vance Margaret A, Schellenberg Gerard D, Farrer Lindsay A, Lunetta Kathryn |
| The Associations Between Cognitive Prognosis and Kynurenines Are Modified by the Apolipoprotein e4 Allele Variant in Patients With Dementia. International journal of tryptophan research : IJTR 2019 12 1178646919885637. Ervik Arne Olav, Hafstad Solvang Stein-Erik, Nordrehaug Jan Erik, Ueland Per Magne, Midttun Øivind, Hildre Audun, McCann Adrian, Nygård Ottar, Aarsland Dag, Giil Lasse Melva |
| Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls. Neurologia (Barcelona, Spain) 2018 Nov . Cruz-Sanabria F, Bonilla-Vargas K, Estrada K, Mancera O, Vega E, Guerrero E, Ortega-Rojas J, Mahecha María F, Romero A, Montañés P, Celeita V, Arboleda H, Pardo |
| Association of Apolipoprotein E e4 With Transactive Response DNA-Binding Protein 43. JAMA neurology 2018 Nov 75 (11): 1347-1354. Wennberg Alexandra M, Tosakulwong Nirubol, Lesnick Timothy G, Murray Melissa E, Whitwell Jennifer L, Liesinger Amanda M, Petrucelli Leonard, Boeve Bradley F, Parisi Joseph E, Knopman David S, Petersen Ronald C, Dickson Dennis W, Josephs Keith |
| Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers. JAMA network open 2018 Oct 1 (6): e183597. Tao Qiushan, Ang Ting Fang Alvin, DeCarli Charles, Auerbach Sanford H, Devine Sheral, Stein Thor D, Zhang Xiaoling, Massaro Joseph, Au Rhoda, Qiu Wei Qi |
| Ancestral origin of ApoE e4 Alzheimer disease risk in Puerto Rican and African American populations. PLoS genetics 2018 12 14 (12): e1007791. Rajabli Farid, Feliciano Briseida E, Celis Katrina, Hamilton-Nelson Kara L, Whitehead Patrice L, Adams Larry D, Bussies Parker L, Manrique Clara P, Rodriguez Alejandra, Rodriguez Vanessa, Starks Takiyah, Byfield Grace E, Sierra Lopez Carolina B, McCauley Jacob L, Acosta Heriberto, Chinea Angel, Kunkle Brian W, Reitz Christiane, Farrer Lindsay A, Schellenberg Gerard D, Vardarajan Badri N, Vance Jeffery M, Cuccaro Michael L, Martin Eden R, Haines Jonathan L, Byrd Goldie S, Beecham Gary W, Pericak-Vance Margaret |
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- Page last updated:Oct 20, 2021
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