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Last Posted: Oct 31, 2023
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Highly cited genetics studies found to contain sequence errors.
Diana Kwon et al. Nature 2023 2

The prevalence of mistakes in published gene research could be more widespread than previously thought, according to an analysis of cancer-genetics papers in two high-impact journals. By combing through the supplementary information for hundreds of papers, a recent study identified some highly cited studies that contain errors in the DNA or RNA sequences of reagents. Scientists use these reagents for various reasons — for example, to study the function of a given gene or genetic sequence in a disease — and if the sequences are wrongly reported it could affect the reproducibility of the research.

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