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Last Posted: Apr 15, 2023
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What Is Marfan Syndrome?
Heidi M Connolly et al. JAMA 2023 4

Marfan syndrome is a genetic disorder that affects connective tissue throughout the body. Marfan syndrome is estimated to affect 1 in 5000 individuals worldwide and occurs with equal frequency in males and females. People with Marfan syndrome often have eye lens dislocation, tall stature, long fingers and toes, flat feet, abnormal curvature of the spine, deformities of the breastbone, and stretch marks on their skin. Abnormal joint mobility, chronic pain, depression, and impaired vision occur more commonly in individuals with Marfan syndrome than in the general population.

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