
Last Posted: Dec 28, 2020
- Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia.
Ballester Veroushka et al. Epigenomics 2020 Dec - Lynch Syndrome-Associated Variants and Cancer Rates in an Ancestrally Diverse Biobank.
Rosenblum Rachel E et al. JCO precision oncology 2020 4 - The "diagnose and leave in" strategy" for diminutive rectosigmoid polyps in Lynch syndrome: a post-hoc analysis from a randomized controlled trial.
Rivero-Sánchez Liseth et al. Endoscopy 2020 Dec - Acquired somatic MMR deficiency is a major cause of MSI tumor in patients suspected for “Lynch-like syndrome” including young patients
S Lefol et al, EJHG, December 5, 2020 - Pembrolizumab in MSI-H–dMMR Advanced Colorectal Cancer — A New Standard of Care
A Grothey, NEJM, December 2, 2020 - Prevalence and clinicopathological/molecular characteristics of mismatch repair protein-deficient tumours among surgically treated patients with prostate cancer in a Japanese hospital-based population.
Kagawa Makoto et al. Japanese journal of clinical oncology 2020 Nov - Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
MD Valentin et al, Genetics in Medicine, December 1, 2020 - Testing for lynch syndrome in people with endometrial cancer using immunohistochemistry and microsatellite instability-based testing strategies - A systematic review of test accuracy.
Stinton Chris et al. Gynecologic oncology 2020 Oct - Cancer Previvors in an Active Duty Service Women Population: An Opportunity for Prevention and Increased Force Readiness.
Lovejoy Leann A et al. Military medicine 2020 Nov - Characteristics of adrenocortical carcinoma associated with Lynch Syndrome.
Domènech Marta et al. The Journal of clinical endocrinology and metabolism 2020 Nov
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Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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