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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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84 hot topic(s) found with the query "Influenza"

Disrupting the gut microbiome may affect some immune responses to flu vaccination
NIH, September 6, 2019 Brand (Posted: Sep-08-2019 2PM)

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.

The 1918 influenza pandemic: 100 years of questions answered and unanswered.
Taubenberger Jeffery K et al. Science translational medicine 2019 Jul (502) (Posted: Jul-26-2019 9AM)

The 2018-2019 period marks the centennial of the "Spanish" influenza pandemic, which caused at least 50 million deaths worldwide.. Unusual features of the pandemic include age-specific mortality and the high frequency of severe pneumonias. Sequencing of the virus has allowed scientists to answer many questions but many more remain.

Preventive care services and health behaviors in children with fragile X syndrome.
Gilbertson Kendra E et al. Disability and health journal 2019 May (Posted: Jul-19-2019 10AM)

This CDC study is the first description of preventive care services specifically received by children and young adults with fragile X syndrome (FXS). 75% of the sample met dental care guidelines, 55.4% met influenza vaccination guidelines, 92.1% met immunization guidelines, and 24.4% met physical activity (PA) guidelines.

Key Findings: Preventive Care Services and Health Behaviors in Children with Fragile X Syndrome
CDC, July 2019 Brand (Posted: Jul-17-2019 8AM)

Only one in four children and young adults with FXS met the physical activity guidance from the United States Department of Health and Human Service. Slightly more than half of the children and young adults with FXS met the CDC recommendation for an annual influenza vaccination.

Flu Outbreak Prediction Using Twitter Posts Classification and Linear Regression With Historical Centers for Disease Control and Prevention Reports: Prediction Framework Study.
Alessa Ali et al. JMIR public health and surveillance 2019 Jun 5(2) e12383 (Posted: Jul-02-2019 9AM)

Social networking sites are widely used. The amount of data within SNSs has created an efficient resource for real-time analysis. Thus, data from SNSs can be used effectively to track disease outbreaks and provide necessary warnings. Current SNS-based flu detection and prediction frameworks apply conventional machine learning approaches that require lengthy training and testing. The objective of this study was to propose an efficient and accurate framework that uses data from SNSs to track disease outbreaks and provide early warnings, even for newest outbreaks, accurately

FluSight: Flu Forecasting
CDC, June 2019 Brand (Posted: Jun-28-2019 9AM)

Can we predict flu? Learn about CDC efforts to predict flu activity. Unlike traditional influenza surveillance systems which measure flu activity after it happens. flu forecasting offers the possibility to look into the future and better plan ahead, potentially reducing the public health impact of flu

Complementing the power of deep learning with statistical model fusion: Probabilistic forecasting of influenza in Dallas County, Texas, USA.
Soliman Marwah et al. Epidemics 2019 Jun 100345 (Posted: Jun-19-2019 9AM)

Summary of Progress since 2009
CDC, June 2019 Brand (Posted: Jun-12-2019 9AM)

Current and future influenza vaccines
S Yamayoshi et al, Nature Medicine, January 28, 2019 (Posted: Jan-29-2019 6PM)

The respiratory microbiome and susceptibility to influenza virus infection.
Lee Kyu Han et al. PloS one 2019 (1) e0207898 (Posted: Jan-20-2019 8AM)

A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States.
Reich Nicholas G et al. Proceedings of the National Academy of Sciences of the United States of America 2019 Jan (Posted: Jan-18-2019 10AM)

Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches
FS Lu et al, Nature Communications, January 11, 2019 (Posted: Jan-12-2019 3PM)

Host and viral determinants of influenza A virus species specificity.
Long Jason S et al. Nature reviews. Microbiology 2018 Nov (Posted: Dec-03-2018 9AM)

Influenza vaccine: Where are we and where do we go?
Keshavarz Mohsen et al. Reviews in medical virology 2018 Nov e2014 (Posted: Dec-03-2018 9AM)

Flu mutations in a single cell help to predict immune response- Genetic diversity of the virus may explain variability in how well a cell fights back.
C Arnold, Nature News, October 29, 2018 (Posted: Oct-29-2018 1PM)

CDC Scientists Become First in History to Directly Sequence the Entire RNA Genomes of Influenza A Viruses
CDC, September26, 2018 Brand (Posted: Sep-26-2018 11AM)

Genomic surveillance of avian-origin influenza A viruses causing human disease.
Lam Tommy T et al. Genome medicine 2018 Jun (1) 50 (Posted: Jul-02-2018 10AM)

Taking flight with Precision Global Health: a scoping review on avian influenza
NE Bempong et al, JPHE, June 2018 (Posted: Jul-02-2018 8AM)

Stanford scientists discover biomarker for flu susceptibility
Stanford University, June 2018 (Posted: Jun-17-2018 1PM)

Influenza Milestones 1917 – 2009 Timeline
Genome of the 1918 pandemic flu virus was fully sequenced in 2005. Brand (Posted: May-07-2018 8AM)

Flu virus finally sequenced in its native form
E Callaway, Nature, Apr 20, 2018 (Posted: Apr-23-2018 11AM)

Weekly U.S. Influenza Surveillance Report
Brand (Posted: Apr-03-2018 8AM)

Despite push for a universal flu vaccine, the ‘holy grail’ stays out of reach
H Branswell, StatNews, Mar 5, 2018 (Posted: Mar-06-2018 8AM)

The emerging influenza virus threat: status and new prospects for its therapy and control.
Kumar Binod et al. Archives of virology 2018 Jan (Posted: Feb-20-2018 9AM)

Know Your Enemy: Successful Bioinformatic Approaches to Predict Functional RNA Structures in Viral RNAs.
Lim Chun Shen et al. Frontiers in microbiology 2017 2582 (Posted: Feb-20-2018 9AM)

6 Things You Need to Know About This Flu Season
CDC Blog post, Feb 5, 2018 (Posted: Feb-07-2018 1PM)

ID’ing features of flu virus genome may help target surveillance for pandemic flu- Findings may help health experts know which strains to watch
T Bhandari, Washington University, Jan 2018 (Posted: Feb-07-2018 0PM)

People at High Risk of Developing Flu–Related Complications
Brand (Posted: Jan-23-2018 0PM)

Prompt Use of Antivirals is Key this Flu Season
Brand (Posted: Jan-22-2018 1PM)

Do you have the cold or the flu?
Brand (Posted: Jan-03-2018 5PM)

Protect Children this Flu Season: Get a Flu Shot!
Some children are at high risk for complications from flu Brand (Posted: Dec-01-2017 10AM)

Detection of influenza C viruses among outpatients and patients hospitalized for severe acute respiratory infection, Minnesota, 2013-2016.
Thielen Beth K et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Oct (Posted: Nov-09-2017 8AM)

Preventive Steps
Brand (Posted: Oct-30-2017 0PM)

Genes may predict how well the flu vaccine will work in young people
A Cunningham. Science News for Students, Sep 26, 2017 (Posted: Sep-27-2017 10AM)

Calculated risk: a new single-nucleotide polymorphism linked to severe influenza disease.
Eisfeld Amie J et al. Nature medicine 2017 Aug (8) 911-912 (Posted: Aug-05-2017 3PM)

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.
Allen E Kaitlynn et al. Nature medicine 2017 Aug (8) 975-983 (Posted: Aug-05-2017 3PM)

Reverse Genetics of Influenza B Viruses.
Nogales Aitor et al. Methods in molecular biology (Clifton, N.J.) 2017 205-238 (Posted: Jul-17-2017 0PM)

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans
EK ALlen et al, Nature Medicine, July 17, 2017 (Posted: Jul-17-2017 11AM)

Just Small Genetic Tweaks To Chinese Bird Flu Virus Could Fuel A Human Pandemic
NPR, June 15, 2017 (Posted: Jun-15-2017 3PM)

Three mutations could make bird flu a potential pandemic: study
Reuters Health, June 15, 2017 (Posted: Jun-15-2017 2PM)

How CDC Is Using Advanced Molecular Detection Technology To Better Fight Flu!
J Barnes, CDC, March 6, 2017 Brand (Posted: Mar-06-2017 6PM)

Reverse Genetics Approaches for the Development of Influenza Vaccines.
Nogales Aitor et al. International journal of molecular sciences 2016 Dec (1) (Posted: Jan-23-2017 11AM)

Respiratory viral infections and host responses; insights from genomics.
Troy Niamh M et al. Respiratory research 2016 Nov (1) 156 (Posted: Dec-20-2016 1PM)

Fight the Flu!
Brand (Posted: Dec-07-2016 11AM)

Improving performance of influenza vaccines through next-generation sequencing and protein
Brand (Posted: Dec-05-2016 9AM)

Using advanced methods to track ever-changing flu viruses
Brand (Posted: Oct-08-2016 9AM)

Update: Influenza Activity — United States and Worldwide, May 22–September 10, 2016
MMWR, September 23, 2016 (Posted: Oct-04-2016 5PM)

Influenza 2016-2017 Season
Brand (Posted: Oct-03-2016 9AM)

Translating genomic sequences into antibody efficacy and safety against influenza toward clinical trial outcomes: a case study.
Yang Hsih-Te et al. Drug discovery today 2016 Jun (Posted: Oct-03-2016 9AM)

Multi-Omics Studies towards Novel Modulators of Influenza A Virus-Host Interaction.
Söderholm Sandra et al. Viruses (10) (Posted: Oct-03-2016 9AM)

Host genetics of severe influenza: from mouse Mx1 to human IRF7.
Ciancanelli Michael J et al. Current opinion in immunology 2016 Feb 109-20 (Posted: Oct-03-2016 9AM)

A genomic signature of influenza infection shows potential for presymptomatic detection, guiding early therapy, and monitoring clinical responses
MT McClain et al, Open Forum Infectious Diseases, February 2016 (Posted: Feb-04-2016 7PM)

Protect Yourself & Your Family Against the Flu
Brand (Posted: Feb-01-2016 1PM)

National Influenza Vaccination Week: December 6-13, 2015
Brand (Posted: Dec-07-2015 10AM)

Metagenomics: A New Way to Illustrate the Crosstalk between Infectious Diseases and Host Microbiome.
Zhang Yinfeng et al. International journal of molecular sciences 2015 (11) 26263-79 (Posted: Nov-07-2015 0PM)

Flu Season is Around the Corner
Brand (Posted: Sep-23-2015 11AM)

Molecular epidemiology study of swine influenza virus revealing a reassorted virus H1N1 in swine farms in Cuba.
Pérez Lester J et al. Prev. Vet. Med. 2015 May 1. (3-4) 172-8 (Posted: Aug-07-2015 10AM)

Global migration of influenza A viruses in swine.
Nelson Martha I et al. Nat Commun 2015 6696 (Posted: Aug-07-2015 10AM)

The repeated introduction of the H3N2 virus from human to swine during 1979-1993 in China.
Zhu Wenfei et al. Infect. Genet. Evol. 2015 Jul 20-4 (Posted: Aug-07-2015 10AM)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013.
Watson Simon J et al. J. Virol. 2015 Jul 22. (Posted: Aug-07-2015 10AM)

Genetic Surveillance Study Finds Flu Viruses at Two US Swine Markets
GenomeWeb, Jul 31, 2015. (Posted: Aug-07-2015 10AM)

Influenza A Viruses of Human Origin in Swine, Brazil.
Nelson Martha I et al. Emerging Infect. Dis. 2015 Aug (8) 1339-47 (Posted: Aug-07-2015 10AM)

Live animal markets in Minnesota: a potential source for emergence of novel influenza A viruses and interspecies transmission.
Choi Mary J et al. Clin. Infect. Dis. 2015 Jul 29. (Posted: Aug-07-2015 10AM)

This little piggy went to market-but perhaps should have stayed home.
Webby Richard et al. Clin. Infect. Dis. 2015 Jul 29. (Posted: Aug-07-2015 10AM)

Under the influence: Is influenza a genetic disease?
The Economist, Mar 28, 2015 (Posted: Apr-30-2015 0PM)

Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.
de Vries Erik et al. Emerging Infect. Dis. 2015 May (5) 842-6 (Posted: Apr-24-2015 9AM)

A Single Gene May Determine Why Some People Get So Sick With The Flu
National Public Radio, March 26, 2015 (Posted: Mar-30-2015 4PM)

Bad gene cripples flu defenses,
by Mitch Leslie, Science Magazine, Mar 26 (Posted: Mar-30-2015 0PM)

A Host Susceptibility Gene, DR1, Facilitates Influenza A Virus Replication by Suppressing Host Innate Immunity and Enhancing Viral RNA Replication.
Hsu Shih-Feng et al. J. Virol. 2015 Apr 1. (7) 3671-82 (Posted: Mar-30-2015 8AM)

Clinical utility comparison of two benchtop deep sequencing instruments for rapid diagnosis of newly emergent influenza infections.
Ren X et al. Clin. Microbiol. Infect. 2014 Oct 29. (Posted: Mar-30-2015 8AM)

Characterization of a large cluster of influenza A(H1N1)pdm09 virus cross-resistant to oseltamivir and peramivir during the 2013/2014 influenza season in Japan.
Takashita Emi et al. Antimicrob. Agents Chemother. 2015 Feb 17. (Posted: Mar-30-2015 8AM)

Variations in genome-wide RNAi screens: lessons from influenza research.
Chou Yu-Chi et al. J Clin Bioinforma 2015 2 (Posted: Mar-30-2015 8AM)

Analysis of the genetic diversity of influenza A viruses using next-generation DNA sequencing.
Van den Hoecke Silvie et al. BMC Genomics 2015 Feb 14. (1) 79 (Posted: Mar-30-2015 8AM)

SnapShot: Evolution of Human Influenza A Viruses.
Wendel Isabel et al. Cell Host Microbe 2015 Mar 11. (3) 416-416.e1 (Posted: Mar-30-2015 8AM)

Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland.
Jalovaara Petri et al. Genome Announc 2015 (2) (Posted: Mar-30-2015 8AM)

Integrated sentinel surveillance linking genetic, antigenic and epidemiologic monitoring of influenza vaccine-virus relatedness and effectiveness, 2013-14 season.
Skowronski Danuta M et al. J. Infect. Dis. 2015 Mar 17. (Posted: Mar-30-2015 8AM)

CDC paper: Emergence of highly pathogenic avian influenza A(H5N1) virus PB1-F2 variants and their virulence in BALB/c mice.
Kamal RP et al. J Virology, March 2015 (Posted: Mar-30-2015 8AM)

A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.
Zaas Aimee K et al. Sci Transl Med 2013 Sep 18. (203) 203ra126 (Posted: Mar-29-2015 2PM)

CDC Information: H5 Viruses in the United States
Brand (Posted: Feb-25-2015 0PM)

Are you at high risk for serious illness from flu? 
Brand (Posted: Feb-25-2015 0PM)

The flu: What to do if you get sick
Brand (Posted: Feb-25-2015 0PM)

Influenza virus genome sequencing and genetic characterization
Brand (Posted: Feb-25-2015 0PM)

Using networks to combine "big data" and traditional surveillance to improve influenza predictions.
Davidson Michael W et al. Sci Rep 2015 8154 (Posted: Feb-13-2015 0PM)

Brand (Posted: Jan-11-2014 11AM)

Influenza, or flu, is a contagious respiratory infection caused by several flu viruses that infect the nose, throat and lungs.. People infected with the seasonal flu virus feel miserable with fever, chills, muscle aches, coughing, congestion, headache and fatigue for a week or so. Most people who get the flu get better within two weeks, but some people may develop serious complications, such as pneumonia. Pandemic influenza is when a new flu virus strain occurs that can spread easily from person-to-person and the virus is one for which most people have no immunity.

Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.