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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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44 hot topic(s) found with the query "Huntington disease "

Association of CAG Repeats With Long-term Progression in Huntington Disease
DR Langbehn et al, JAMA Neurology, August 12, 2019 (Posted: Aug-13-2019 8AM)


Experimental Drug For Huntington's Disease Jams Malfunctioning Gene
R Harris, NPR, May 9, 2019 (Posted: May-10-2019 9AM)


Recent advances in the therapeutic development for Huntington disease.
Mestre Tiago A et al. Parkinsonism & related disorders 2019 Feb 125-130 (Posted: May-06-2019 4PM)


Targeting Huntingtin Expression in Patients with Huntington’s Disease
SJ Tabrizi et al, NEJM, May 6, 2019 (Posted: May-06-2019 4PM)


27 years of prenatal diagnosis for Huntington disease in the United Kingdom
RE Pina-Aguilar et al, Genetics in Medicine, December 14, 2018 (Posted: Dec-14-2018 1PM)


Concise Review: The Use of Stem Cells for Understanding and Treating Huntington's Disease.
Connor Bronwen et al. Stem cells (Dayton, Ohio) 2017 Nov (Posted: Dec-11-2017 9AM)


Genetics of Huntington disease.
Nance Martha A et al. Handbook of clinical neurology 2017 3-14 (Posted: Nov-06-2017 6AM)


The impact of Huntington disease on young people.
Ellison Matthew et al. Handbook of clinical neurology 2017 144179-182 (Posted: Oct-04-2017 10AM)


The highly anxious individual presenting for Huntington disease-predictive genetic testing: the psychiatrist's role in assessment and counseling.
Groves Mark et al. Handbook of clinical neurology 2017 14499-105 (Posted: Oct-04-2017 10AM)


Genetic testing for Huntington disease.
Quaid Kimberly A et al. Handbook of clinical neurology 2017 144113-126 (Posted: Oct-04-2017 10AM)


What do we know about Late Onset Huntington's Disease?
Chaganti Sai S et al. Journal of Huntington's disease 2017 (2) 95-103 (Posted: Aug-08-2017 0PM)


Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.
Wright Dean J et al. Advances in neurobiology 2017 93-128 (Posted: Aug-08-2017 0PM)


The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.
Tippett Lynette J et al. Advances in neurobiology 2017 129-161 (Posted: Aug-08-2017 0PM)


Can CRISPR Conquer Huntington’s?
R Lewis, PLOS Blogs, June 28, 2017 (Posted: Jun-29-2017 11AM)


Huntington's Disease-Update on Treatments.
Wyant Kara J et al. Current neurology and neuroscience reports 2017 Apr (4) 33 (Posted: Jun-27-2017 9AM)


REVIEW-ARTICLE Intermediate alleles of Huntington's disease HTT gene in different populations worldwide: a systematic review.
Apolinário T A et al. Genetics and molecular research : GMR 2017 Apr (2) (Posted: Jun-27-2017 9AM)


Palliative Care in Huntington Disease: Personal Reflections and a Review of the Literature.
Tarolli Christopher G et al. Tremor and other hyperkinetic movements (New York, N.Y.) 2017 454 (Posted: Jun-27-2017 9AM)


Huntington’s Disease: Gene Editing Shows Promise in Mouse Studies
F Collins, NIH director blog, June 27, 2017 Brand (Posted: Jun-27-2017 9AM)


Personal utility in genomic testing: is there such a thing?
Bunnik Eline M et al. Journal of medical ethics 2015 Apr (4) 322-6 (Posted: Jun-06-2017 11AM)


A Systematic Review of the Huntington Disease-Like 2 Phenotype.
Anderson David G et al. Journal of Huntington's disease 2017 (1) 37-46 (Posted: May-20-2017 10AM)


Modern Genome Editing Technologies in Huntington's disease Research.
Malankhanova Tuyana Bairovna et al. Journal of Huntington's disease 2017 Jan (Posted: Feb-26-2017 4PM)


A liminal stage after predictive testing for Huntington disease.
Gargiulo Marcela et al. Journal of medical genetics 2017 Jan (Posted: Jan-18-2017 10AM)


Factors Related to Genetic Testing in Adults at Risk for Huntington Disease: The Prospective Huntington At-Risk Observational Study (PHAROS).
Quaid Kimberly A et al. Clinical genetics 2016 Oct (Posted: Oct-19-2016 3PM)


Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease- Randomized Clinical Trial
Huntington's Study group. JAMA July 5, 2016 (Posted: Jul-06-2016 7AM)


Huntington Disease Update
R Lewis, PLOS Blogs, February 29, 2016 (Posted: Mar-01-2016 6PM)


Pridopidine for the treatment of Huntington's disease.
Shannon Kathleen M et al. Expert opinion on investigational drugs 2016 Feb (Posted: Mar-01-2016 8AM)


The Frequency of Huntington Disease and Huntington Disease-Like 2 in the South African Population.
Baine Fiona K et al. Neuroepidemiology 2016 Feb (3) 198-202 (Posted: Mar-01-2016 8AM)


Huntington disease among the Navajo: A population-based study in the Navajo Nation.
Gordon Paul H et al. Neurology 2016 Feb (Posted: Mar-01-2016 8AM)


Neuropsychiatric symptoms are very common in premanifest and early stage Huntington's Disease.
Martinez-Horta Saul et al. Parkinsonism & related disorders 2016 Feb (Posted: Mar-01-2016 8AM)


Current status of PET imaging in Huntington's disease.
Pagano Gennaro et al. European journal of nuclear medicine and molecular imaging 2016 Feb (Posted: Mar-01-2016 8AM)


Huntington disease: Blocking DREAM delays neurodegeneration.
Crunkhorn Sarah et al. Nature reviews. Drug discovery 2016 Feb (Posted: Mar-01-2016 8AM)


Potential Treatment for Huntington's Disease Enters Clinical Testing
SciCasts Clinical Research, February 29, 2016 (Posted: Mar-01-2016 8AM)


Huntington disease and the potential of gene silencing
Genomics Education Program, October 26, 2015 (Posted: Oct-27-2015 10AM)


Genetic Counselling for Predictive Testing in Huntington's Disease in One Centre since 1993. Gender-Specific Aspects of Decision-Making.
Arning Larissa et al. J Huntingtons Dis 2015 4(1) 87-98 (Posted: Sep-09-2015 11AM)


Finding Factors that Affect Huntington’s Disease Onset
NIH Research Matters, August 31, 2015 Brand (Posted: Sep-01-2015 10AM)


Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease
Genetic Modifiers of Huntington?s Disease (GeM-HD) Consortium GeM-HD Consortium, Cell, July 30, 2015 (Posted: Jul-31-2015 7AM)


Predictive genetic testing for Huntington's disease: A journey with a genetic counselor as your guide,
National Society of Genetic Counselors, Jun 18 (Posted: Jun-24-2015 1PM)


Can We Cure Huntington's Disease?
ricki Lewis, PLoS Blog DNA Science Posts, May 28, 2015 (Posted: Jun-01-2015 11AM)


Noninvasive prenatal diagnosis of Huntington disease: detection of the paternally inherited expanded CAG repeat in maternal plasma.
van den Oever Jessica M E et al. Prenat. Diagn. 2015 Mar 12. (Posted: Apr-23-2015 8AM)


Cognitive interventions to enhance neural compensation in Huntington's disease.
Andrews Sophie C et al. Neurodegener Dis Manag 2015 Apr (2) 155-64 (Posted: Apr-23-2015 8AM)


Huntington disease: Cerebrospinal fluid and MRI biomarkers for prodromal HD.
Chase Alex et al. Nat Rev Neurol 2015 Apr 21. (Posted: Apr-23-2015 8AM)


Huntington disease
GP Bates et al. Nature Reviews Disease Primers, April 23, 2015 (Posted: Apr-23-2015 8AM)


Juvenile Huntington disease
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan-01-2011 0AM)


Huntington disease
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan-01-2011 0AM)



Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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