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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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192 hot topic(s) found with the query "Genomic medicine"

Implementation science and genomic medicine in action: A case study
M Clyne et al, CDC Blog, September 18, 2019 Brand (Posted: Sep-19-2019 9AM)

An ideal opportunity to understand how a genomic research activity falls into the implementation science realm is to read through the details of an applicable study. Here, we will guide you through a study on ”Implementing Universal Lynch Syndrome Screening: Identifying Strategies to Facilitate and Maintain Programs in Different Organizational Contexts."


Genetic Counseling and Public Health in the Era of Precision Medicine
MJ Khoury, CDC Blog, September 18, 2019 Brand (Posted: Sep-19-2019 9AM)

As more genetic counselors make a leap from individual patient care to population health concerns including implementation and disparities, genetic counselors will help enhance the public’s genetic awareness and literacy about genomics and family health history, contribute to policy, evaluation and implementation, and drive the overall success of genomic medicine.


Genome sequencing in healthcare: understanding the UK general public’s views and implications for clinical practice
LM Ballard et al, Eur J Humn Genetics, September 16, 2019 (Posted: Sep-17-2019 7AM)

The study garnered public views regarding genome sequencing, incidental findings (IFs), and sharing genetic information with relatives. Participants (n?=?1954) from the British general public completed a survey, distributed via email. Overall, the public had a positive view of genomic sequencing, choosing ‘informative’ as the most popular word.


Predictive value of genomic screening: cross-sectional study of cystic fibrosis in 50,788 electronic health records
JP Sugunarajav et al, NPJ Genomic Medicine, September 5, 2019 (Posted: Sep-06-2019 7AM)

Despite EHR-based phenotyping limitations, the presence or absence of pathogenic CFTR variants has strong predictive value for CF diagnosis when EHR data is used as the sole phenotyping source.


The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system.
Mandl Kenneth D et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Sep (Posted: Sep-05-2019 8AM)


Has Genomic Medicine Delivered in Cancer?
DJ Kerr, Medscape, August 2019 (Posted: Sep-05-2019 8AM)


Recognition of Board-Certified Clinical Laboratory Professionals as Qualified Healthcare Professionals
ACMG, August 29, 2019 (Posted: Aug-29-2019 9AM)

The American College of Medical Genetics and Genomics (ACMG) strongly recommends that appropriately trained and board-certified doctoral level clinical laboratory professionals be recognized as Qualified Healthcare Professionals (QHPs).


NIH announces six inaugural Genomic Innovator Awards
NIH, August 27, 2019 Brand (Posted: Aug-28-2019 7AM)


If You Build It Will They Come? The Urgent Need for Implementation Science in Genomic Medicine
M Clyne et al, CDC Blog, 2017 Brand (Posted: Aug-26-2019 11AM)


Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes
P Feliciano et al, NPJ Genomic Medicine, August23, 2019 (Posted: Aug-23-2019 11AM)


Is Genetic Medicine Making the World Less Fair?
L Hercher, the Nation, August 23, 2019 (Posted: Aug-23-2019 9AM)


Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network
eMERGE consortium, AJHG, August 22, 2019 (Posted: Aug-23-2019 8AM)

This study integrated structured genomic results into multiple electronic health record systems, setting the stage for clinical decision support to enable genomic medicine. The established processes enable different sequencing sites to harmonize interpretation of sequencing tests, a critical achievement toward global standardization of genomic testing.


Genomic medicine: time for health-care transformation
RH Scott et al, The Lancet, August 6, 2019 (Posted: Aug-06-2019 11AM)


Genomic Medicine Series
The Lancet, August 5, 2019 (Posted: Aug-06-2019 9AM)

The maturing area of genomic medicine, encompassing the use of individuals’ genetic information to guide clinical treatment, is featured in this Series. In these five, timely reviews, authors present an overview of efforts to implement genomic medicine, including contemporary tools and resources.


The Human Genomic Revolution: Past, Present, and Future
E. Lander presentation, Broad Institute, July 2019 (Posted: Aug-05-2019 8AM)

Over 15 years ago, the scientific community celebrated the sequencing of the first human genome. It’s time to ask how this monumental effort has transformed biomedical science, from basic research to the understanding and treatment of disease. Eric Lander surveys the impact — what we’ve learned, and what lies ahead.


Family still matters: Counseling patients with complex family histories of colon and endometrial cancers.
Gemmell Amber P et al. Molecular genetics & genomic medicine 2019 Jul e886 (Posted: Jul-31-2019 8AM)

There are no national guidelines for the management of patients with a family history consistent with Lynch syndrome (LS) but a negative genetic test. To determine current management practices, genetic counselors' (GCs) recommendations were assessed.


Can Equity in Genomic Medicine Become a Quality Goal?
NHGRI 1-hour webinar by Katrina Armstrong, July 2019 Brand (Posted: Jul-29-2019 1PM)


Implementation of a genomic medicine multi-disciplinary team approach for rare disease in the clinical setting: a prospective exome sequencing case series.
Taylor John et al. Genome medicine 2019 Jul (1) 46 (Posted: Jul-29-2019 1PM)

The study reports a consecutive case series of 132 patients (involving 10 medical specialties with 43.2% cases having a neurological disorder) undergoing exome sequencing over a 10-month period.The costs of running the MDT are also reported.


What will it take to implement genomics in practice? Lessons from the IGNITE Network.
Ginsburg Geoffrey S et al. Personalized medicine 2019 Jul (Posted: Jul-28-2019 4PM)

While many aspects of implementation science are generic, the unique features of genomic medicine call for adapting current implementation science models to meet the needs of patients, providers and health systems adopting these complex interventions. Since 2013, the IGNITE network has faced numerous challenges. To enable future research, those challenges and our insights for solutions are highlighted.


Genomic knowledge in the contextstic exome sequencing: changes over time, persistent subgroup differences, and associations with psychological sequencing outcomes.
Rini Christine et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Jul (Posted: Jul-20-2019 4PM)

People undergoing diagnostic genome-scale sequencing are expected to have better psychological outcomes when they can incorporate and act on accurate, relevant knowledge that supports informed decision making. The NCGENES study of diagnostic exome sequencing to evaluate associations between factual genomic knowledge and sequencing outcomes.


Genomics: the power, potential and pitfalls of the new technologies and how they are transforming healthcare.
Josephs Katherine S et al. Clinical medicine (London, England) 2019 Jul (4) 269-272 (Posted: Jul-19-2019 8AM)

New genomic technologies are transforming healthcare. Within the next decade, healthcare professionals will be using genomic data to diagnose and manage their patients. Despite these advances, few clinicians are prepared for this genomics-based future. Through five patient-focused scenarios, this article showcases new genomic technologies while highlighting the inherent challenges associated with complex genomic data.


New journal article and films highlight progress in genomics
Genomics Education Program, July 18, 2019 (Posted: Jul-18-2019 0PM)


The changing face of clinical genetics service delivery in the era of genomics: a framework for monitoring service delivery and data from a comprehensive metropolitan general genetics service.
Fennell Andrew Paul et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Jul (Posted: Jul-15-2019 9AM)

Clinical genetics is an evolving specialty. Methods for monitoring implementation and workflow changes are needed. This literature review shows inconsistent metrics and lays out a framework for further use.


Secondary findings from next generation sequencing: Psychological and ethical issues. Family and patient perspectives.
Houdayer F et al. European journal of medical genetics 2019 Jun 103711 (Posted: Jul-10-2019 8AM)

Access to active search for actionable secondary findings (SF) in diagnostic practice is a major psychological and ethical issue for genomic medicine. In this study, the authors analyzed the preferences of patients and their families regarding SF and identified the reporting procedures necessary for informed consent


Genetic Variation, Comparative Genomics, and the Diagnosis of Disease.
Eichler Evan E et al. The New England journal of medicine 2019 Jul (1) 64-74 (Posted: Jul-05-2019 8AM)


Australian Genomics: A Federated Model for Integrating Genomics into Healthcare.
Stark Zornitza et al. American journal of human genetics 2019 Jul (1) 7-14 (Posted: Jul-05-2019 8AM)

Australian Genomics is a national collaborative research partnership of more than 80 organizations piloting a whole-of-system approach to integrating genomics into healthcare that is based on federation principles. The aim of Australian Genomics is to assess the application of genomic testing in healthcare at the translational interface between research and clinical delivery.


Analyzing and Reanalyzing the Genome: Findings from the MedSeq Project
K Machini et al, AJHG, June 27, 2019 (Posted: Jun-28-2019 8AM)

Although genome sequencing is increasingly available in clinical and research settings, many questions remain about the interpretation of sequencing data. The Medseq project finds substantial numbers of new and reclassified variants in genome sequencing results over time. The study highlights the need for periodic reinterpretation and reanalysis of genome data, a major challenge for genomic medicine.


Educating healthcare providers in the delivery of genomic medicine
J McCarthy et al, Pers Medicine, June 2019 (Posted: Jun-27-2019 8AM)

Foreword to a special focus issue on genomics education of health care providers. including articles on implementing personalized medicine cancer program in a community cancer system, provider engagement in precision oncology and pharmacogenomic education for health care professionals through electronic educational courses.


Veterans Genomic Cohort Nearing 1 Million
R Rubin, JAMA, June 25, 2019 (Posted: Jun-27-2019 8AM)

The Million Veteran Program, a voluntary research initiative studying how genes affect veterans? health, recently enrolled its 750 000th participant. The program, which began enrolling veterans in 2011, has grown into one of the largest research cohorts of its kind in the world, and it has the greatest representation of minorities of any US genomic cohort.


Incidence, demographic characteristics, and geographic distribution of sickle cell trait and sickle cell anemia births in Michigan, 1997-2014.
Reeves Sarah L et al. Molecular genetics & genomic medicine 2019 Jun e795 (Posted: Jun-26-2019 9AM)


Intermountain, Amgen subsidiary to launch DNA study of 500,000 patients
A Joseph, Stat News, June 12, 2019 (Posted: Jun-12-2019 7AM)


Genomic malpractice: what healthcare providers need to know to reduce the risk
J McCarthy, Precision Medicine Advisor, June 10, 2019 (Posted: Jun-11-2019 8AM)


Long-Read Sequencing Emerging in Medical Genetics.
Mantere Tuomo et al. Frontiers in genetics 2019 10426 (Posted: May-29-2019 9AM)


Continuous pharmacogenomics and genomic medicine education for healthcare professionals through electronic educational courses.
Tsermpini Evangelia-Eirini et al. Personalized medicine 2019 May (Posted: May-29-2019 9AM)


Introduction to Genomics
NHGRI, 2019 Brand (Posted: May-23-2019 8AM)


The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research
CR Horowtiz et al, Cell, May 16, 2019 (Posted: May-17-2019 7AM)


Genomics’ “Green” Future
J Lemieux, GEN News, May 1, 2019 (Posted: May-03-2019 7AM)


The Convergence of Research and Clinical Genomics
E Birney, AJHG, May 2, 2019 (Posted: May-02-2019 4PM)


Gene discovery informatics toolkit defines candidate genes for unexplained infertility and prenatal or infantile mortality
R Dawes et al, NPJ Genomic Medicine, April 15, 2019 (Posted: Apr-29-2019 11AM)


Genomic Medicine Meets Public Health in the Prevention of Cardiovascular Disease: Familial Hypercholesterolemia as a Paradigm
CDC Webinar, May 30, 2019 Brand (Posted: Apr-28-2019 7AM)


The Responsibility to Recontact Research Participants after Reinterpretation of Genetic and Genomic Research Results.
Bombard Yvonne et al. American journal of human genetics 2019 Apr (4) 578-595 (Posted: Apr-08-2019 9AM)


Application whole exome sequencing for the clinical molecular diagnosis of patients with Duchenne muscular dystrophy; identification of four novel nonsense mutations in four unrelated Chinese DMD patients.
Zhang Yan et al. Molecular genetics & genomic medicine 2019 Apr e622 (Posted: Apr-03-2019 9AM)


A duty to recontact in genetics: context matters
NAA. Giesbertz et al, Nature Reviews Genetics, April 2019 (Posted: Apr-01-2019 9AM)


Regarding the rights and duties of Clinical Laboratory Geneticists in genetic healthcare systems; results of a survey in over 50 countries
T Liehr et al, Eur J Human Genetics, March 28, 2019 (Posted: Mar-29-2019 10AM)


Implementing genomic medicine towards universal health coverage 2030
Global Alliance on Genomics and Health, 2019 (Posted: Mar-28-2019 8AM)


Medical Genetics Awareness Week, April 2019
ACMG, March 2019 (Posted: Mar-27-2019 10AM)


Defining and Achieving Health Equity in Genomic Medicine.
Jooma Sonya et al. Ethnicity & disease 2019 29(Suppl 1) 173-178 (Posted: Mar-27-2019 9AM)


Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field.
Roberts Megan C et al. Ethnicity & disease 2019 29(Suppl 1) 187-192 (Posted: Mar-27-2019 9AM)


IGNITE network: Response of patients to genomic medicine interventions.
Orlando Lori A et al. Molecular genetics & genomic medicine 2019 Mar e636 (Posted: Mar-27-2019 8AM)


Genomic Medicine-Progress, Pitfalls, and Promise.
Shendure Jay et al. Cell 2019 Mar 177(1) 45-57 (Posted: Mar-27-2019 8AM)


Largescale population genomics versus deep phenotyping: Brute force or elegant pragmatism towards precision medicine
L Yehia et al, NPJ Genomic Medicine, March 26, 2019 (Posted: Mar-26-2019 9AM)


Assessing optimism and pessimism about genomic medicine: Development of a Genomic Orientation (GO) scale.
Horrow Caroline et al. Clinical genetics 2019 Mar (Posted: Mar-20-2019 9AM)


Genomic Health Care Today and Tomorrow: Expert Perspectives.
Jenkins Jean F et al. Seminars in oncology nursing 2019 Feb (1) 131-143 (Posted: Mar-07-2019 10AM)


Early Lessons from the Implementation of Genomic Medicine Programs.
Williams Marc S et al. Annual review of genomics and human genetics 2019 Feb (Posted: Mar-06-2019 10AM)


The secret to a new drug could be hiding in your genes- Companies are searching gene databases for people whose DNA says they should be very sick, but who aren’t.
A Regalado, MIT Tech Review, February 2019 (Posted: Mar-04-2019 8AM)


Translating genomic medicine to the clinic: challenges and opportunities.
Zhang Huan et al. Genome medicine 2019 Feb (1) 9 (Posted: Mar-01-2019 11AM)


A decade of Genome Medicine: toward precision medicine
Rabia Begum Genome Medicine 2019 11:13 (Posted: Mar-01-2019 11AM)


Defining and Achieving Health Equity in Genomic Medicine
S Jooma et al, Ethn Dis. 2019;29(Suppl 1): 173-178 (Posted: Feb-21-2019 11AM)


Leveraging Implementation Science to Address Health Disparities in Genomic Medicine:Examples from the Field
MC Roberts et al, Ethncity and Disease, 2019(suppl 1): 187-192. (Posted: Feb-21-2019 11AM)


Health research: Applying genome technologies to the study of disease
Open Access News, February 18, 2019 (Posted: Feb-18-2019 0PM)


Ten years of Genome Medicine
C Auffray et al, Genome Medicine, February 15, 2019 (Posted: Feb-15-2019 11AM)


Using deep learning to identify translational research in genomic medicine beyond bench to bedside
YY Hsu et al, Database, February 2019 (Posted: Feb-08-2019 1PM)


Current conditions in medical genetics practice
DR Maisese et al, Genetics in Medicine, January 28, 2019 (Posted: Jan-28-2019 11AM)


Turn your head, cough, submit your DNA: Your next physical may include genetic testing
Chicago Tribune, January 25, 2019 (Posted: Jan-28-2019 7AM)


Spinning the Genome: Why Science Hype Matters.
Caulfield Timothy et al. Perspectives in biology and medicine 2018 61(4) 560-571 (Posted: Jan-23-2019 2PM)


The contribution of genomics in the medicine of tomorrow, clinical applications and issues.
Laviolle Bruno et al. Therapie 2018 Dec (Posted: Jan-23-2019 2PM)


Where is genomics going next?
B Cheifet, Genome Biology, January 22, 2019 (Posted: Jan-22-2019 10AM)


Color Partnering With Health Systems Exploring Impact of Genomic Testing on Outcomes, Cost
T Ray, Genomeweb, January 11, 2019 (Posted: Jan-12-2019 3PM)


Research Focus: beyond the 100 000 genomes
G Watts, The Lancet, January 2019 (Posted: Jan-06-2019 8AM)


Integrating Genomics into Healthcare: A Global Responsibility
Z Stark et al, AJHG, January 3, 2019 (Posted: Jan-04-2019 9AM)


All the reasons 2018 was a breakout year for DNA data
A Regalado, MIT Tech Review, December 29, 2018 (Posted: Dec-30-2018 4PM)


Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy
MA Corbett et al,. NPJ Genomic Medicine, Decemeber 2018 (Posted: Dec-20-2018 8AM)


New algorithm could accelerate diagnosis of genetic diseases using clinical records
H Santoro, Stanford Blog, December 2018 (Posted: Dec-18-2018 8AM)


Your invaluable genome-Genomic data is the currency of a new era of medicine that promises incredible advances
Genomics Education UK, October 2018 (Posted: Nov-21-2018 0PM)


Understanding Disparities in Access to Genomic Medicine: Proceedings of a Workshop
NASEM workshop, November 2018 (Posted: Nov-14-2018 9AM)


Implementing universal Lynch syndrome screening (IMPULSS): protocol for a multi-site study to identify strategies to implement, adapt, and sustain genomic medicine programs in different organizational contexts
AK Rahm et al, BMC Health Services Res, October 30, 2018 (Posted: Nov-01-2018 11AM)


Stakeholders’ views on the value of outcomes from clinical genetic and genomic interventions
M Scheuner et al, Genetics in Medicine, October 31, 2018 (Posted: Oct-31-2018 8AM)


UK Biobank — a new era in genomic medicine
OG Bahcall, Nat Rev Genetics, October 23, 2018 (Posted: Oct-24-2018 8AM)


Clinical whole-exome sequencing results impact medical management.
Niguidula Nancy et al. Molecular genetics & genomic medicine 2018 Oct (Posted: Oct-17-2018 8AM)


NIH-supported projects remove major obstacles standing in the way of genomic medicine
NIH News, October 12, 2018 Brand (Posted: Oct-15-2018 10AM)


The NHS genomic service could transform medicine
The Economist, September 2018 (Posted: Sep-28-2018 11AM)


Heterogeneity in clinical sequencing tests marketed for autism spectrum disorders
Ny Hoang et al, npj Genomic Medicine, Sepetmber 19, 2018 (Posted: Sep-19-2018 1PM)


Enhancing diversity to reduce health information disparities and build an evidence base for genomic medicine.
Hindorff Lucia A et al. Personalized medicine 2018 Sep (Posted: Sep-19-2018 9AM)


Genomic Medicine: Are We Ready?
S Harris, Medscape, September 2018 (Posted: Sep-12-2018 8AM)


User considerations in assessing pharmacogenomic tests and their clinical support tools
G. Mukherjee et al, NPJ Genomic Medicine, September 11, 2018 (Posted: Sep-11-2018 2PM)


Genomic Medicine XI: Research Directions in Genomic Medicine Implementation
NHGRI, September 5-6, 2018 Brand (Posted: Aug-28-2018 9AM)


Genomic medicine must reduce, not compound, health inequities: the case for hauora-enhancing genomic resources for New Zealand.
Robertson Stephen P et al. The New Zealand medical journal 2018 Aug 131(1480) 81-89 (Posted: Aug-22-2018 11AM)


Precision Public Health and Genomic Medicine
Healthcare special supplement, 2018 (Posted: Aug-14-2018 9AM)


Medical genetics in developing countries in the Asia-Pacific region: challenges and opportunities
MT Thong et al, Genetics in Medicine, August 10, 2018 (Posted: Aug-10-2018 0PM)


Understanding Disparities in Access to Genomic Medicine: A Workshop
NASEM workshop from the roundtable on genomics and precision health: Workshop slides and videos, August 2018 (Posted: Aug-03-2018 11AM)


The Path to Routine Genomic Screening in Health Care
M Murray, Annals of Internal Medicine, July 30, 2018 (Posted: Jul-31-2018 8AM)


Health Disparities in Implementation of Genomic Medicine: Challenges and Opportunities
CDC Webinar, August 24, 2018 Brand (Posted: Jul-24-2018 9AM)


Responsible sharing of biomedical data and biospecimens via the “Automatable Discovery and Access Matrix” (ADA-M)
JP Woolley et al, npj Genomic Medicine, July 23, 2018 (Posted: Jul-23-2018 11AM)


Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs
JL Williams et al, Healthcare 201, 6(3)8 (Posted: Jul-17-2018 8AM)


Training for our digital future: a human-centered design approach to graduate medical education for aspiring clinician-innovators
J Carter et al, npj Genomic Medicine, July 16, 2018 (Posted: Jul-16-2018 8AM)


Is Genomic Medicine Failing Minority Patients?
B Furlow, Cancer Therapy Advisor, July 2018 (Posted: Jul-14-2018 10AM)


Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network
KD Levy et al, Genetics in Medicine, July 12, 2018 (Posted: Jul-12-2018 6PM)


How Routine Genomic Medicine 'Will Change People's Lives'
P Russell, Medscape, July 11, 2018 (Posted: Jul-12-2018 8AM)


Program is first to use the patient’s DNA in routine healthcare to better treat or prevent disease
Geisinger, July 10, 2018 (Posted: Jul-10-2018 3PM)


Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases
MM Clark et al, Nature Genomic Medicine, July 2018 (Posted: Jul-10-2018 8AM)


Routine DNA tests will put NHS at the 'forefront of medicine'
I Sample, The Guardian, July 3, 2018 (Posted: Jul-04-2018 7AM)


Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge
I Sundin et al, Bioinformatics, July 2018 (Posted: Jul-02-2018 8AM)


Genomics, data, and AI - a perfect birthday gift?
S Raza, PHG Foundation, June 29, 2018 (Posted: Jul-02-2018 8AM)


Developing a ‘2020 Vision’ for Genomics
E Green, ASHG Blog Post, June 2018 (Posted: Jun-18-2018 8AM)


Genome-wide sequencing in acutely ill infants: genomic medicine’s critical application?
JM Friedman et al, Genetics in Medicine, June 12, 2018 (Posted: Jun-12-2018 11AM)


The Undergraduate Training in Genomics (UTRIG) Initiative: early & active training for physicians in the genomic medicine era.
Wilcox Rebecca L et al. Personalized medicine 2018 May (Posted: Jun-11-2018 11AM)


Pharmacogenomics: From classroom to practice.
Nutter Samantha C et al. Molecular genetics & genomic medicine 2018 May (Posted: Jun-11-2018 11AM)


Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example.
Aronson Samuel et al. Journal of the American Medical Informatics Association : JAMIA 2018 May (Posted: Jun-11-2018 11AM)


Assessing patient readiness for personalized genomic medicine.
Frost Caren J et al. Journal of community genetics 2018 May (Posted: Jun-09-2018 5PM)


Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association
K Musunuru et al, Circulation: Genomics and Precision Medicine, May 2018 (Posted: May-29-2018 0PM)


Physician Preparedness for Big Genomic Data: A Review of Genomic Medicine Education Initiatives in the United States.
Rubanovich Caryn Kseniya et al. Human molecular genetics 2018 May (Posted: May-16-2018 9AM)


Genetic Testing to Assess Risk of Heart Attack
A Cook. Center for Genomic Medicine, May 9, 2018 (Posted: May-16-2018 7AM)


Investigator-Initiated Genomic Medicine Research (R01 Clinical Trial Optional)
NHGRI, 2018 Brand (Posted: May-11-2018 0PM)


Genome Sequencing in the Clinic: The Past, Present, and Future of Genomic Medicine.
Prokop Jeremy W et al. Physiological genomics 2018 May (Posted: May-09-2018 8AM)


Patient-Centered Precision Health In A Learning Health Care System: Geisinger’s Genomic Medicine Experience
MW Williams et al, Health Affairs, May 2018 (Posted: May-08-2018 8AM)


Understanding Disparities in Access to Genomic Medicine: A Workshop
NASEM, June 27, 2018 workshop announcement (Posted: Apr-19-2018 8AM)


Doctors don’t feel qualified to interpret genomic tests, concludes Cambridge’s PHG Foundation
P Brackley, Cambridge Independent, Apr 2018 (Posted: Apr-10-2018 8AM)


Genetic counselling in the era of genomic medicine
C Patch et al, British Med Bulletin, Apr 2018 (Posted: Apr-03-2018 8AM)


Genomics—an aid to diagnosis not a replacement
I Torjesen, BMJ, Mar 23, 2018 (Posted: Mar-26-2018 9AM)


Genetics for your whole life
Editorial, Nature Genetics, Mar 5, 2018 (Posted: Mar-05-2018 1PM)


Consumer use and response to online third-party raw DNA interpretation services.
Wang Catharine et al. Molecular genetics & genomic medicine 2018 Jan 6(1) 35-43 (Posted: Feb-28-2018 10AM)


Successful translation? Consider the value of implementation
P Bedford, Signals Blog,Feb 26, 2018 (Posted: Feb-27-2018 0PM)


Maternal sepsis in the era of genomic medicine.
Kouskouti C et al. Archives of gynecology and obstetrics 2018 Jan (1) 49-60 (Posted: Feb-26-2018 9AM)


The Forefront of Genomics
Watch a video from the National Human Genome Research Institute, Feb 2018 Brand (Posted: Feb-22-2018 9AM)


Leveraging the Learning Health Care Model to Improve Equity in the Age of Genomic Medicine.
Blizinsky Katherine D et al. Learning health systems 2018 Jan 2(1) (Posted: Feb-21-2018 10AM)


Application of the GRADE Approach in the Development of Guidelines and Recommendations in Genomic Medicine.
Rafiq Muhammad et al. Genomics insights 2018 111178631017753360 (Posted: Feb-14-2018 0PM)


Developing a 2020 vision for genomics: NHGRI launches new round of strategic planning
NHGRI< Feb 12, 2018 Brand (Posted: Feb-12-2018 0PM)


gnomAD browser beta | genome Aggregation Database
Jan 25, 2018 (Posted: Jan-25-2018 0PM)


The Cult Of DNA-centricity
D Grainger, Forbes, Jan 24, 2018 (Posted: Jan-25-2018 9AM)


Preparing the Way: Exploiting Genomic Medicine to Stop Smoking.
Bierut Laura J et al. Trends in molecular medicine 2018 Jan (Posted: Jan-23-2018 9AM)


Genomics in mainstream clinical pathways
PHG Foundation, Jan 9, 2018 (Posted: Jan-12-2018 10AM)


Further support for clinicians essential for success of genomic medicine, urge experts
http://www.phgfoundation.org/phg-news/further-support-for-clinicians-essential-for-genomics (Posted: Jan-12-2018 10AM)


Genomics in 2018: 3 key predictions
Genomics Education UK, Jan, 2018 (Posted: Jan-06-2018 6AM)


Happy birthday, Genetics in Medicine!
JE Evans, Genetics in Medicine, January 2018 (Posted: Jan-04-2018 9AM)


Preparing for genomic medicine: a real world demonstration of health system change.
Gaff Clara L et al. NPJ genomic medicine 2017 216 (Posted: Jan-03-2018 10AM)


Patients with sporadic and familial amyotrophic lateral sclerosis found value in genetic testing.
Wagner Karin N et al. Molecular genetics & genomic medicine 2017 Dec (Posted: Jan-03-2018 10AM)


Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications.
Kalsner Louisa et al. Molecular genetics & genomic medicine 2017 Dec (Posted: Jan-03-2018 10AM)


"Not pathogenic until proven otherwise": perspectives of UK clinical genomics professionals toward secondary findings in context of a Genomic Medicine Multidisciplinary Team and the 100,000 Genomes Project.
Ormondroyd Elizabeth et al. Genetics in medicine : official journal of the American College of Medical Genetics 2017 Oct (Posted: Jan-03-2018 10AM)


How Health IT Advancements Make Genomic Medicine a Reality
J Van Wegenen, Health IT, Dec 2017 (Posted: Dec-11-2017 1PM)


"Not pathogenic until proven otherwise”: perspectives of UK clinical genomics professionals toward secondary findings in context of a Genomic Medicine Multidisciplinary Team and the 100,000 Genomes Project
E Onrmondroyd et al, genetics in Medicine, Oct 26, 2017 (Posted: Oct-30-2017 2PM)


Medicine's future? In an ambitious experiment, a rural U.S. health system is trying to integrate genomic screening into routine care.
BP Trivedi, Science, Oct 27, 2017 (Posted: Oct-27-2017 6AM)


The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis
Roberts MC et al, Genetics in Medicine, Oct 26, 2017 (Posted: Oct-26-2017 3PM)


1993-2014: two decades of predictive testing for Huntington's disease at the Medical Genetics Unit of the University of Genoa.
Mandich Paola et al. Molecular genetics & genomic medicine 2017 Sep 5(5) 473-480 (Posted: Sep-27-2017 9AM)


Genomic medicine and data sharing.
Raza Sobia et al. British medical bulletin 2017 Sep 123(1) 35-45 (Posted: Sep-20-2017 11AM)


Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group.
Orlando Lori A et al. Genetics in medicine : official journal of the American College of Medical Genetics 2017 Sep (Posted: Sep-16-2017 8AM)


Navigating the research–clinical interface in genomic medicine: analysis from the CSER Consortium
SM Wolfe et al, Genetics in Medicine, August 31, 2017 (Posted: Aug-31-2017 0PM)


Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond.
Schork N J et al. Advances in genetics 2017 9781-113 (Posted: Aug-30-2017 9AM)


New UCSF Program Aims to Advance Equity in Genomic Medicine in the Bay Area
UCSF News, N Weiler, August 29, 2017 (Posted: Aug-30-2017 9AM)


Multilevel research and the challenges of implementing genomic medicine.
Khoury Muin J et al. Journal of the National Cancer Institute. Monographs 2012 May (44) 112-20 (Posted: Aug-23-2017 5PM)


Why We Can’t Wait: A Public Health Approach to Health Disparities in Genomic Medicine
MJ Khoury, CDC Blog Post, 2013 Brand (Posted: Jul-31-2017 8PM)


Division of Genomic Medicine- Notices & Funding Opportunities-IGNITE 2.0
NHGRI, July 25, 2017 (Posted: Jul-26-2017 6PM)


Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort.
Garton Fleur C et al. Molecular genetics & genomic medicine 2017 Jul 5(4) 418-428 (Posted: Jul-26-2017 9AM)


Identifying Health Information Technology Needs of Oncologists to Facilitate the Adoption of Genomic Medicine: Recommendations From the 2016 American Society of Clinical Oncology Omics and Precision Oncology Workshop
KS Hughes et al, J CLin Oncol, July 24, 2017 (Posted: Jul-24-2017 7PM)


Precision Genetic and Genomic Medicine in the Middle East and North Africa Region: Are We There Yet?
Bilani Nadeem et al. Public health genomics 2017 May (Posted: Jun-13-2017 1PM)


No Shortcuts on the Long Road to Evidence-Based Genomic Medicine.
Khoury Muin J et al. JAMA 2017 Jun (Posted: Jun-06-2017 9AM)


The rules remain the same for genomic medicine: the case against "reverse genetic exceptionalism".
Evans James P et al. Genetics in medicine : official journal of the American College of Medical Genetics 2010 Jun (6) 342-3 (Posted: Jun-02-2017 9AM)


Are there any shortcuts on the translation highway to genomic medicine?
MJ Khoury, CDC Blog Post, June 1, 2017 Brand (Posted: Jun-01-2017 5PM)


Massive-scale genomic data sharing to improve rare disease diagnosis
D MacArthu8r VIDEO presentation, Scripps Institute, Future of Genomic Medicine 2017 (Posted: Apr-21-2017 8AM)


Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research
KA Phillips et al, Genetics in Medicine, April 13, 2017 (Posted: Apr-13-2017 0PM)


Carrier Screening in the Age of Genomic Medicine
ACOG, March 2017 (Posted: Feb-25-2017 0PM)


Implementation Science in Genomic Medicine: Why we need it now!
MC Roberts et al, CDC blog post, February 2017 Brand (Posted: Feb-03-2017 7AM)


Newborn Sequencing in Genomic Medicine and Public Health
JS Berg et al, Pediatrics, January 2017 (Posted: Jan-17-2017 4PM)


The current state of implementation science in genomic medicine: opportunities for improvement
MC Roberts et al, Genetics in Medicine, January 12, 2017 Brand (Posted: Jan-12-2017 0PM)


Genomic Medicine Without Borders
Genome Magazine, January 2017 (Posted: Jan-11-2017 8PM)


A comprehensive global genotype–phenotype database for rare diseases
R. Trujillano et al, Molecular Genetics and Genomic Medicine, November 2016 (Posted: Dec-01-2016 7AM)


From "Personalized" to "Precision" Medicine: The Ethical and Social Implications of Rhetorical Reform in Genomic Medicine.
Juengst Eric et al. The Hastings Center report 2016 Sep 46(5) 21-33 (Posted: Sep-27-2016 11AM)


Known unknowns: building an ethics of uncertainty into genomic medicine
AJ Newson et al, BMC Medical Genetics, September 1, 2016 (Posted: Sep-06-2016 7AM)


Eye Melanoma, Media Hype, and Genomic Medicine
R Lewis, PLOS Blogs, September 1, 2016 (Posted: Sep-01-2016 4PM)


The evolving Promise of Genomic Medicine
IBM, July 2016 (Posted: Jul-28-2016 7PM)


Lead toxicity and genetics in Flint, MI
JY Taylor et al, Genomic Medicine, June 2016 (Posted: Jun-28-2016 1PM)


Applying an Implementation Science Approach to Genomic Medicine: Workshop Summary
National Academy of Medicine, Workshop Report, April 28, 2016 (Posted: Apr-29-2016 8AM)


Comparative effectiveness research and genomic medicine: an evolving partnership for 21st century medicine.
Khoury Muin J et al. Genetics in medicine : official journal of the American College of Medical Genetics 2009 Oct (10) 707-11 (Posted: Nov-23-2015 11AM)


GINA, genetic discrimination, and genomic medicine.
Green Robert C et al. The New England journal of medicine 2015 Jan (5) 397-9 (Posted: Nov-12-2015 2PM)


Is Genomic Medicine Finally Coming of Age for the Diagnosis of Pneumonia?
Opal Steven et al. American journal of respiratory and critical care medicine 2015 Oct (7) 773-4 (Posted: Nov-11-2015 7PM)


Genetic testing and economic evaluations: a systematic review of the literature.
D'Andrea Elvira et al. Epidemiologia e prevenzione 39(4 Suppl 1) 45-50 (Posted: Oct-28-2015 9AM)


Knowledge integration at the center of genomic medicine.
Khoury Muin J et al. Genetics in medicine : official journal of the American College of Medical Genetics 2012 Jul (7) 643-7 (Posted: Oct-19-2015 3PM)


Actionable clinical decisions based on comprehensive genomic evaluation in asymptomatic adults.
Pillar Nir et al. Molecular genetics & genomic medicine 2015 Sep 3(5) 433-9 (Posted: Oct-06-2015 2PM)


Walking Before Running: Genomic Medicine 10 Years After the Human Genome Project
Brand (Posted: Oct-05-2015 9AM)


Genomic Medicine in the Real World: 'Hope' and 'Hype'
D Hunter al. Harvard School of Public Health, June 2015 (Posted: Jul-06-2015 10AM)


Precision Genomic Medicine in Cystic Fibrosis.
Chang Eugene H et al. Clin Transl Sci 2015 Jun 15. (Posted: Jun-18-2015 0PM)


The future of genomic medicine education in Africa
GH SIw et al. Genome Medicine, May 2015 (Posted: May-26-2015 1PM)


Evidence synthesis and guideline development in genomic medicine: current status and future prospects.
Schully Sheri D et al. Genet. Med. 2015 Jan (1) 63-7 (Posted: Mar-03-2015 0PM)


Reconciling the future of genomic medicine with its current reality
Brand (Posted: Feb-25-2015 0PM)


Genetic Testing and FDA Regulation: Overregulation Threatens the Emergence of Genomic Medicine.
Evans James P et al. JAMA 2015 Feb 17. (7) 669-670 (Posted: Feb-18-2015 3PM)


Training future physicians in the era of genomic medicine: trends in undergraduate medical genetics education.
Plunkett-Rondeau Jevon et al. Genet. Med. 2015 Feb 12. (Posted: Feb-13-2015 11AM)


Personalized medicine, availability, and group disparity: an inquiry into how physicians perceive and rate the elements and barriers of personalized medicine.
Petersen Katelin E et al. Public Health Genomics 2014 (4) 209-20 (Posted: Feb-13-2015 10AM)


Health disparities in genomics and genetics.
Spruill Ida J et al. Nurs Res Pract 2014 324327 (Posted: Feb-13-2015 10AM)


Translation and validation of a Spanish-language genetic health literacy screening tool.
Rodríguez Sally Ann et al. Health Psychol 2015 Feb (2) 120-9 (Posted: Feb-13-2015 10AM)


Effects of racial and ethnic group and health literacy on responses to genomic risk information in a medically underserved population.
Kaphingst Kimberly A et al. Health Psychol 2015 Feb (2) 101-10 (Posted: Feb-13-2015 10AM)


Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities.
Mersha Tesfaye B et al. Hum. Genomics 2015 Jan 7. (1) 1 (Posted: Feb-13-2015 10AM)


Introduction to the special series on health disparities in genomic medicine.
Graves Kristi D et al. Health Psychol 2015 Feb (2) 97-100 (Posted: Feb-13-2015 10AM)


The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?
Khoury Muin J et al. Genetics in medicine : official journal of the American College of Medical Genetics 2007 Oct (10) 665-74 (Posted: Jan-01-2014 0AM)



Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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