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Last Posted: Apr 27, 2023
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Association of Glucose-6-Phosphate Dehydrogenase Deficiency With Outcomes in US Veterans With COVID-19.
Sarah H Elsea et al. JAMA network open 2023 3 (3) e235626

Is G6PD deficiency, the most common enzyme deficiency in the world, associated with COVID-19 severity in US veterans? In this cohort study of 24?700 veterans, G6PD deficiency was present in 9.4% of veterans with SARS-CoV-2 infection and was associated with a 1.5-fold increased likelihood of severe outcomes in male veterans less than 65 years of age who self-identified as Black, and a 3.6-fold greater likelihood of severe outcomes in male veterans 65 years of age and older who self-identified as White.

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