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Last Posted: Feb 07, 2023
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Reemergence of Cholera in Haiti.
Rubin Daniel H F et al. The New England journal of medicine 2022 11

To decipher the relationship between the current outbreak strain and other toxigenic O1 El Tor strains from the ongoing seventh pandemic of cholera, we sequenced the isolate obtained on September 30, 2022, along with four isolates obtained in 2021 and 2022 from Dhaka, Bangladesh. Phylogenetic analysis of more than 1200 isolates revealed that the 2022 Haiti isolate was closely related to the 2010 Nepal isolate that was the origin of the initial outbreak. These analyses suggest that the reemergence of cholera in Haiti in 2022 was caused, at least in part, by a descendant of the V. cholerae strain that caused the 2010 epidemic. However, no cases of cholera were confirmed between 2019 and 2022, despite ongoing surveillance.

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