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Last Posted: Feb 27, 2024
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A Novel HPV/Host DNA Methylation-Score and Detection of Cervical Adenocarcinoma.
Ana Gradissimo et al. J Natl Cancer Inst 2023 7

The widespread introduction of Pap testing in the 1960second was followed by significant reductions in the incidence of cervical squamous cell cancer (SCC). However, the incidence of cervical adenocarcinoma (ADC) did not decrease, likely because of low Pap test sensitivity for ADC and adenocarcinoma in situ (AIS). This study assessed a novel HPV/host DNA Methylation-Score for AIS/ADC screening.

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