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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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84 hot topic(s) found with the query "Breast and ovarian cancer "

General “Take Action” Infographic
CDC Cancer, 2019 Brand (Posted: Oct-08-2019 8AM)

Lower your risk of hereditary breast and ovarian cancer. Asking relatives about their cancer histories can be hard. Follow these tips: Share that you have learned that cancers can run in families. Explain that you are creating a record of your family’s history of cancer. •Encourage family members to respond in a way that is most comfortable to them.


Population prevalence of individuals meeting criteria for hereditary breast and ovarian cancer testing.
Greenberg Samantha et al. Cancer medicine 2019 Sep (Posted: Sep-25-2019 9AM)


Randomised trial of population-based BRCA testing in Ashkenazi Jews: long-term outcomes.
Manchanda R et al. BJOG : an international journal of obstetrics and gynaecology 2019 Sep (Posted: Sep-18-2019 9AM)

Unselected population-based BRCA testing provides the opportunity to apply genomics on a population-scale to maximize primary prevention for breast-and-ovarian cancer. The study compared long-term outcomes of Ashkenazi jewish population-based and family-history (FH)/clinical-criteria-based BRCA testing on psychological health and quality of life


Learn Your Family History of Breast and Ovarian Cancer
CDC, 2019 Brand (Posted: Sep-16-2019 8AM)

Learning your family history of cancer, from both your mother’s and father’s sides, can help you know if you have a higher risk for getting breast or ovarian cancer at a young age.Asking your relatives about their cancer histories can be hard. Here are some tips for talking with your family about this topic.


USPSTF Recommendation Expands Cancer Screening Pool, Concerns Still Remain
KL Kahl, Cure, August 26, 2019 (Posted: Aug-27-2019 7AM)

Many see the new USPSTF guidelines as a major step forward in genetics. However, the updated recommendation still comes with concerns: It failed to include newly diagnosed patients with breast or ovarian cancer as well as patients with advanced cancers. In addition, it did not include men. Fifty percent of people with a BRCA mutation are men.


Genetic Testing Can Reduce Suffering and Save Lives
L Corduck, AJMC, August 14, 2019 (Posted: Aug-15-2019 8AM)

I am Oneinforty. In late 2016 at the age of 45, I sought genetic counseling and screening after a friend’s urging. The screening showed I had inherited a BRCA gene mutation, putting my lifetime risk of developing breast cancer between 50% and 80%, and my lifetime risk of developing ovarian cancer (for which there is limited screening) between 40% and 60%.


PARP Inhibitors Hit the Pancreatic Cancer Scene
D Ternyila, Oncology Nursing News, August 9, 2019 (Posted: Aug-13-2019 8AM)

PARP inhibitors, which have approved indications in breast and ovarian cancer, are expanding to additional treatment paradigms, including pancreatic cancer. Data from the phase III POLO trial showed that PARP inhibitor significantly improved progression-free survival among patients with germline BRCA-mutated metastatic pancreatic cancer.


Infographic: “What Every Young Woman Needs to Know About Hereditary Breast and Ovarian Cancer”
CDC, 2019 Brand (Posted: Jul-17-2019 9AM)


The 2019 HBOC and Lynch Syndrome Family Day
Michigan Public Health Institute, Register for event, September 21, 2019 (Posted: Jul-12-2019 8AM)

The 2019 HBOC and Lynch Syndrome Family Day is a patient-focused educational event designed to bring together people and families who have been impacted by hereditary breast and ovarian cancer (HBOC) or Lynch syndrome. Attendees at this free event will learn about hereditary cancer risks and ways to manage risk.


Nevada Health Study Using Genetics To Fight Disease Statewide
N Glick, KUNR, June 28, 2019 (Posted: Jul-01-2019 1PM)

The Healthy Nevada Project kicked off in 2016, and so far, has around 50,000 participants. Its aim is to eventually reach 1 million people across Nevada. Anyone can sign up, which is what makes it the largest community-based population health study of its kind in the world. For now, the study is looking for three gene variants that are linked to colon cancer, high cholesterol and breast and ovarian cancer.


Developing a culturally targeted video to enhance the use of genetic counseling in Latina women at increased risk for hereditary breast and ovarian cancer.
Hurtado-de-Mendoza Alejandra et al. Journal of community genetics 2019 May (Posted: May-22-2019 8AM)


Consensus guidelines for genetic testing for hereditary breast and ovarian cancer
American Society for Breast Surgeons, February 14, 2019 (Posted: Feb-16-2019 0PM)


Reinterpretation of BRCA1 and BRCA2 variants of uncertain significance in patients with hereditary breast/ovarian cancer using the ACMG/AMP 2015 guidelines.
So Min-Kyung et al. Breast cancer (Tokyo, Japan) 2019 Feb (Posted: Feb-12-2019 10AM)


High-risk breast cancer surveillance with MRI: 10-year experience from the German consortium for hereditary breast and ovarian cancer.
Bick Ulrich et al. Breast cancer research and treatment 2019 Feb (Posted: Feb-12-2019 10AM)


Challenges and Opportunities for Cancer Predisposition Cascade Screening for Hereditary Breast and Ovarian Cancer and Lynch Syndrome in Switzerland: Findings from an International Workshop.
Nikolaidis Christos et al. Public health genomics 2019 Jan 1-12 (Posted: Jan-30-2019 9AM)


Communication About Hereditary Cancers on Social Media: A Content Analysis of Tweets About Hereditary Breast and Ovarian Cancer and Lynch Syndrome.
Allen Caitlin G et al. Journal of cancer education : the official journal of the American Association for Cancer Education 2018 Dec (Posted: Dec-09-2018 4PM)


Prevalence of nonfounder BRCA1/2 mutations in Ashkenazi Jewish patients presenting for genetic testing at a hereditary breast and ovarian cancer center.
Frey Melissa K et al. Cancer 2018 Nov (Posted: Dec-04-2018 10AM)


Personalised medicine and population health: breast and ovarian cancer.
Narod Steven A et al. Human genetics 2018 Oct (Posted: Oct-20-2018 4PM)


Population-based genetic testing of asymptomatic women for breast and ovarian cancer susceptibility.
Rowley Simone M et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Sep (Posted: Sep-27-2018 7AM)


BRCA1 and BRCA2 Testing in Medically Underserved Medicare Beneficiaries With Breast or Ovarian Cancer
AL Gross et al, JAMA, August 14, 2018 (Posted: Aug-15-2018 8AM)


Improving comprehension of genetic counseling for hereditary breast and ovarian cancer clients with a visual tool.
Tea Muy-Kheng M et al. PloS one 2018 13(7) e0200559 (Posted: Jul-18-2018 9AM)


Underdiagnosis of Hereditary Breast and Ovarian Cancer in Medicare Patients: Genetic Testing Criteria Miss the Mark.
Yang Shan et al. Annals of surgical oncology 2018 Jul (Posted: Jul-13-2018 2PM)


Genetic screening can inform women of their breast and ovarian cancer risks
L Abaid, LA Times, July 5, 2018 (Posted: Jul-06-2018 8AM)


The uptake of presymptomatic genetic testing in hereditary breast-ovarian cancer and Lynch syndrome: a systematic review of the literature and implications for clinical practice.
Menko Fred H et al. Familial cancer 2018 May (Posted: Jun-11-2018 11AM)


Concurrent risk-reduction surgery in patients with increased lifetime risk for breast and ovarian cancer: an analysis of the National Surgical Quality Improvement Program (NSQIP) database.
Elmi Maryam et al. Breast cancer research and treatment 2018 May (Posted: May-25-2018 8AM)


National Distribution of Cancer Genetic Testing in the United States- Evidence for a Gender Disparity in Hereditary Breast and Ovarian Cancer
K Childers et al, JAMA Onc, Apr 26, 2018 (Posted: Apr-27-2018 1PM)


Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study
F Girardi et al, Genetics in Medicine, Mar 22, 2018 (Posted: Mar-22-2018 0PM)


Inherited BRCA1 epimutation as a novel cause of breast and ovarian cancer
DGR Evans, BioRXIV, Jan 2018 (Posted: Jan-22-2018 1PM)


Investigating barriers to genetic counseling and germline mutation testing in women with suspected hereditary breast and ovarian cancer syndrome and Lynch syndrome.
Shaw Josephine et al. Patient education and counseling 2017 Dec (Posted: Jan-03-2018 10AM)


Professionals' knowledge, attitude and referral behaviour of preimplantation genetic diagnosis for hereditary breast and ovarian cancer.
Gietel-Habets J J G et al. Reproductive biomedicine online 2017 Dec (Posted: Dec-17-2017 0PM)


Randomized Noninferiority Trial of Telephone vs In-Person Genetic Counseling for Hereditary Breast and Ovarian Cancer: A 12-Month Follow-Up
MK Interrante et al, JNCI Cancer Spectrum, Sept 2017 (Posted: Dec-01-2017 9AM)


Breast and Ovarian Cancer Penetrance Estimates Derived From Germline Multiple-Gene Sequencing Results in Women
AW Kurian et al, J Precision Oncology, Oct 2017 (Posted: Oct-15-2017 11AM)


Genetic/Familial High Risk Assessment: Breast and Ovarian Cancer
NCCN Guidelines, October 2017 (Posted: Oct-06-2017 0PM)


Cancer Predisposition Cascade Screening for Hereditary Breast/Ovarian Cancer and Lynch Syndromes in Switzerland: Study Protocol.
Katapodi Maria C et al. JMIR research protocols 2017 Sep 6(9) e184 (Posted: Sep-27-2017 10AM)


Practice Bulletin No. 182 Summary: Hereditary Breast and Ovarian Cancer Syndrome.
et al. Obstetrics and gynecology 2017 Sep 130(3) 657-659 (Posted: Aug-30-2017 9AM)


Practice Bulletin No 182: Hereditary Breast and Ovarian Cancer Syndrome.
et al. Obstetrics and gynecology 2017 130(3) e110-e126 (Posted: Aug-30-2017 9AM)


National Estimates of Genetic Testing in Women With a History of Breast or Ovarian Cancer.
Childers Christopher P et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Aug JCO2017736314 (Posted: Aug-24-2017 1PM)


Take Action to Lower Your Breast and Ovarian Cancer Risk
Brand (Posted: Jul-13-2017 3PM)


Breast and Ovarian Cancer Penetrance Estimates Derived From Germline Multiple-Gene Sequencing Results in Women
AW Kurian, JCO Precision Oncology, June 27, 2017 (Posted: Jun-28-2017 0PM)


Age-specific overall risk of breast, ovarian cancer among women with BRCA1/2 genetic mutations
Science Mag, June 20, 2017 (Posted: Jun-25-2017 3PM)


"When information is not enough": A model for understanding BRCA-positive previvors' information needs regarding hereditary breast and ovarian cancer risk.
Dean Marleah et al. Patient education and counseling 2017 Mar (Posted: Apr-12-2017 8AM)


Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.
Müller Dirk et al. The European journal of health economics : HEPAC : health economics in prevention and care 2017 Apr (Posted: Apr-12-2017 8AM)


Risk of breast cancer after a diagnosis of ovarian cancer in BRCA mutation carriers: Is preventive mastectomy warranted?
McGee Jacob et al. Gynecologic oncology 2017 Mar (Posted: Mar-22-2017 10AM)


NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.
Daly Mary B et al. Journal of the National Comprehensive Cancer Network : JNCCN 2017 Jan 15(1) 9-20 (Posted: Jan-11-2017 9AM)


Tracking the dissemination of a culturally targeted brochure to promote awareness of hereditary breast and ovarian cancer among Black women.
Scherr Courtney Lynam et al. Patient education and counseling 2016 Oct (Posted: Nov-30-2016 11AM)


Breast and Ovarian Cancer
Brand (Posted: Oct-10-2016 1PM)


Psychosocial outcomes and counselee satisfaction following genetic counseling for hereditary breast and ovarian cancer: A patient-reported outcome study.
Oberguggenberger Anne et al. Journal of psychosomatic research 2016 Oct 8939-45 (Posted: Sep-27-2016 11AM)


Hereditary breast and ovarian cancer: successful systematic implementation of a group approach to genetic counselling.
Benusiglio Patrick R et al. Familial cancer 2016 Sep (Posted: Sep-21-2016 10AM)


Public Health Approaches and Barriers to Educating Providers about Hereditary Breast and Ovarian Cancer Syndrome.
Trepanier Angela M et al. Healthcare (Basel, Switzerland) 2016 4(1) (Posted: Jul-19-2016 10AM)


Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel.
Yablonski-Peretz Tamar et al. Breast cancer research and treatment 2016 Jan (1) 133-8 (Posted: Jan-12-2016 10AM)


SEOM clinical guidelines in Hereditary Breast and ovarian cancer.
Llort G et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2015 Dec 17(12) 956-61 (Posted: Dec-29-2015 10AM)


The Activities and Impact of State Programs to Address Hereditary Breast and Ovarian Cancer, 2011–2014
K Trivers et al, Healthcare, December 2015 (Posted: Nov-01-2015 2PM)


Initial Results of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer and Lynch Syndrome.
Howarth Dt R et al. The American surgeon 2015 Oct (10) 941-4 (Posted: Oct-31-2015 9AM)


Next-Generation Gene Sequencing: Looking Beyond Hereditary Breast and Ovarian Cancer.
Estrada Sylvia S et al. Oncology nursing forum 2015 Nov (6) 691-4 (Posted: Oct-31-2015 9AM)


Does Breast or Ovarian Cancer Run in Your Family?
Brand (Posted: Oct-20-2015 4PM)


Utilization and Outcomes of BRCA Genetic Testing and Counseling in a National Commercially Insured PopulationThe ABOUT Study
J Armstrong et al. JAMA Oncology, October 1, 2015 (Posted: Oct-05-2015 9AM)


Genetic Testing for BRCA Mutations Today and Tomorrow - About the ABOUT Study
S Narod, JAMA Oncology, October 1, 2015 (Posted: Oct-05-2015 9AM)


Genetic testing all women for breast cancer might not be worth the cost
Science Daily, September 3, 2015 (Posted: Sep-10-2015 1PM)


Are videoconferenced consultations as effective as face-to-face consultations for hereditary breast and ovarian cancer genetic counseling?
Zilliacus Elvira M et al. Genet. Med. 2011 Nov (11) 933-41 (Posted: Sep-09-2015 0PM)


Cost-effectiveness of Universal BRCA1/2 Screening - Evidence-Based Decision Making
EF Long et al. JAMA Oncology, September 3, 2015 (Posted: Sep-03-2015 3PM)


A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients.
Lincoln Stephen E et al. J Mol Diagn 2015 Jul 21. (Posted: Jul-27-2015 9AM)


Risk-reducing surgery in hereditary gynecological cancer: Clinical applications in Lynch syndrome and hereditary breast and ovarian cancer.
Adachi Masataka et al. Mol Clin Oncol 2015 Mar (2) 267-273 (Posted: Apr-29-2015 7PM)


Risk of Breast and Ovarian Cancers May Differ by BRCA1/2 Mutation Type
ASCO Post, April 8, 2015 (Posted: Apr-09-2015 8AM)


Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.
Rebbeck Timothy R et al. JAMA 2015 Apr 7. (13) 1347-61 (Posted: Apr-09-2015 8AM)


Implementing a screening tool for identifying patients at risk for hereditary breast and ovarian cancer: a statewide initiative.
Brannon Traxler L et al. Ann. Surg. Oncol. 2014 Oct (10) 3342-7 (Posted: Apr-07-2015 3PM)


'Jolie effect': Could her candor help save lives?
By Maria Puente, USA Today, Mar 24 (Posted: Mar-25-2015 1PM)


What all patients can learn from Angelina Jolie,
by Julia Belluz and Steven Hoffman, Vox, Mar 24 (Posted: Mar-25-2015 1PM)


Diary of a Surgery
Angelina Jolie Pitt, New York Times, March 24, 2015 (Posted: Mar-24-2015 11AM)


CDC Podcast Genetics and BRCA in Primary Care
(Posted: Mar-24-2015 7AM)


Webinar: Hereditary Breast and Ovarian Cancer in Public Health
Genetic Alliance, 2014 (Posted: Mar-24-2015 7AM)


Research progress in applying proteomics technology to explore early diagnosis biomarkers of breast cancer, lung cancer and ovarian cancer.
Luo Lu et al. Asian Pac. J. Cancer Prev. 2014 (20) 8529-38 (Posted: Mar-04-2015 8PM)


Hereditary breast and ovarian cancer- Public Health Implementation Toolkit
Brand (Posted: Feb-25-2015 0PM)


CDC Information: Does Breast or Ovarian Cancer Run in Your Family?
Brand (Posted: Feb-25-2015 0PM)


Knowing BRCA Changed My Life
By Debbie Wasserman Schultz, CDC Blog Post 2014 Brand (Posted: Feb-25-2015 0PM)


CDC Know:BRCA Tool
Some women carry certain genetic changes in their BRCA genes that increase their risks for getting breast, ovarian, and other kinds of cancers at a young age Brand (Posted: Feb-25-2015 0PM)


Population testing for cancer predisposing BRCA1/BRCA2 mutations in the Ashkenazi-Jewish community: a randomized controlled trial.
Manchanda Ranjit et al. J. Natl. Cancer Inst. 2015 Jan (1) 379 (Posted: Feb-16-2015 8AM)


Cost-effectiveness of population screening for BRCA mutations in Ashkenazi jewish women compared with family history-based testing.
Manchanda Ranjit et al. J. Natl. Cancer Inst. 2015 Jan (1) 380 (Posted: Feb-16-2015 8AM)


Population-based screening for BRCA1 and BRCA2: 2014 Lasker Award.
King Mary-Claire et al. JAMA 2014 Sep 17. (11) 1091-2 (Posted: Feb-16-2015 8AM)


Lasker Award winner Mary-Claire King.
King Mary-Claire et al. Nat. Med. 2014 Oct (10) 1124-5 (Posted: Feb-16-2015 8AM)


Population-based screening for breast and ovarian cancer risk due to BRCA1 and BRCA2.
Gabai-Kapara Efrat et al. Proc. Natl. Acad. Sci. U.S.A. 2014 Sep 30. (39) 14205-10 (Posted: Feb-16-2015 8AM)


Precision medicine meets public health: population screening for BRCA1 and BRCA2.
Levy-Lahad Ephrat et al. J. Natl. Cancer Inst. 2015 Jan (1) 420 (Posted: Feb-16-2015 8AM)


A Never-Ending Genetic Quest. Mary-Claire King?s Pioneering Gene Work, From Breast Cancer to Human Rights
New York times, February 9, 2015 (Posted: Feb-16-2015 8AM)


BRCA2 hereditary breast and ovarian cancer syndrome
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan-01-2011 0AM)


BRCA1 hereditary breast and ovarian cancer syndrome
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan-01-2011 0AM)



Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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