Archive
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
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Archived Hot Topics of the Day By Date
Next-generation sequencing and bioinformatics in rare movement disorders.
Michael Zech et al. Nat Rev Neurol 2024 1
(Posted: Jan 15, 2024 10AM)
Grand challenges in bioinformatics education and training.
Esra Büsra Isik et al. Nat Biotechnol 2023 8 (8) 1171-1174
(Posted: Aug 25, 2023 2PM)
Genetic Profiles Affect Smokers' Lung Cancer Risk
CN Martimez, Medscape, August 2023
(Posted: Aug 11, 2023 11AM)
How to fight antibiotic resistance.
Mike May et al. Nat Med 2023 7 (7) 1583-1586
(Posted: Jul 19, 2023 7AM)
ReporTree: a surveillance-oriented tool to strengthen the linkage between pathogen genetic clusters and epidemiological data.
Verónica Mixão et al. Genome Med 2023 6 (1) 43
(Posted: Jun 20, 2023 7AM)
Pathogen genomics in public health laboratories: successes, challenges, and lessons learned from California's SARS-CoV-2 Whole-Genome Sequencing Initiative, California COVIDNet.
Emily A Smith et al. Microb Genom 2023 6 (6)
(Posted: Jun 04, 2023 2PM)
Genome-based surveillance offers new hope in the fight against healthcare-associated infections
P Bose, News Medical, May 2, 2023
(Posted: May 05, 2023 10AM)
Development of an amplicon-based sequencing approach in response to the global emergence of human monkeypox virus
NFG Chen et al, MEDRXIV, January 13, 2023
(Posted: Jan 16, 2023 7AM)
An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance
NL Sherry et al, Nature Comm, January 4, 2023
(Posted: Jan 05, 2023 5AM)
Development and Trends in Artificial Intelligence in Critical Care Medicine: A Bibliometric Analysis of Related Research over the Period of 2010–2021
X Cui et al, J Per Med, December 27, 2022
(Posted: Dec 28, 2022 11AM)
CDC announces $90M funding to support new Pathogen Genomics Centers of Excellence network
CDC, September 20, 2022
(Posted: Sep 21, 2022 7AM)
Big data in basic and translational cancer research.
Jiang Peng et al. Nature reviews. Cancer 2022 9
(Posted: Sep 07, 2022 8AM)
miRNAs as potential diagnostic biomarkers and pharmacogenomic indicators in psychiatric disorders.
Tsermpini Evangelia Eirini et al. The pharmacogenomics journal 2022 6
(Posted: Jun 28, 2022 7AM)
Whole-exome sequencing improves the diagnosis and care of men with non-obstructive azoospermia.
Kherraf Zine-Eddine et al. American journal of human genetics 2022 2
(Posted: Feb 17, 2022 11AM)
Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting.
Gorzynski John E et al. The New England journal of medicine 2022 1
(Posted: Jan 13, 2022 8AM)
Reporting guidelines for human microbiome research: the STORMS checklist
C Mirzayi et al, Nature Medicine, November 17, 2021
(Posted: Nov 18, 2021 5AM)
The growing need for controlled data access models in clinical proteomics and metabolomics
TM Keane et al, Nature Communications, October 2021
(Posted: Oct 04, 2021 9AM)
Discovering disease-causing pathogens in resource-scarce Southeast Asia using a global metagenomic pathogen monitoring system
JA Bohl et al, MEDRXIV, September 28, 2021
(Posted: Sep 29, 2021 5AM)
Genome-wide identification and prediction of SARS-CoV-2 mutations show an abundance of variants: Integrated study of bioinformatics and deep neural learning.
MS Hossain et al, BIORXIV, May 24, 2021
(Posted: May 25, 2021 6AM)
Is “bioinformatics” dead?
P Bourne, PLOS Biology, March 2021
(Posted: Mar 22, 2021 7AM)
The impact of mutations on the structural and functional properties of SARS-CoV-2 proteins: A comprehensive bioinformatics analysis
A Ikram et al, BIORXIV, March 1, 2021
(Posted: Mar 03, 2021 6AM)
Want to track pandemic variants faster? Fix the bioinformatics bottleneck
EB Hodcroft et al, Nature, March 1, 2021
(Posted: Mar 03, 2021 6AM)
Bioinformatics, Sequencing Accuracy, and the Credibility of Clinical Genomics
WG Feero, JAMA, November 17, 2020
(Posted: Nov 17, 2020 0PM)
Identification of key genes in SARS-CoV-2 patients on bioinformatics analysis
H Gu et al, BIORXIV, September 6, 2020
(Posted: Sep 07, 2020 10AM)
Identification of potential key genes for SARS-CoV-2 infected human bronchial organoids based on bioinformatics analysis
H Gu et al, BIORXIV, August 19, 2020
(Posted: Aug 20, 2020 8AM)
Genome Sequencing during a Patient's Journey through Cancer.
Nangalia Jyoti et al. The New England journal of medicine 2019 Nov (22) 2145-2156
(Posted: Nov 28, 2019 9AM)
Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction.
Williams Jason J et al. PloS one 2019 (11) e0224288
(Posted: Nov 21, 2019 7AM)
Next Generation Sequencing and Bioinformatics Methodologies for Infectious Disease Research and Public Health: Approaches, Applications, and Considerations for Development of Laboratory Capacity.
Maljkovic Berry Irina et al. The Journal of infectious diseases 2019 Oct
(Posted: Oct 30, 2019 9AM)
Fostering bioinformatics education through skill development of professors: Big Genomic Data Skills Training for Professors.
Zhan Yingqian Ada et al. PLoS computational biology 2019 Jun (6) e1007026
(Posted: Aug 13, 2019 8AM)
Bioinformatics, Big Data, and Cancer
NCI, March 2019
(Posted: Mar 31, 2019 5PM)
Highlights on the Application of Genomics and Bioinformatics in the Fight Against Infectious Diseases: Challenges and Opportunities in Africa.
Bah Saikou Y et al. Frontiers in genetics 2018 575
(Posted: Dec 13, 2018 10AM)
Privacy-Preserving Linkage of Genomic and Clinical Data Sets.
Baker Dixie et al. IEEE/ACM transactions on computational biology and bioinformatics 2018 Jul
(Posted: Aug 01, 2018 10AM)
A new bioinformatics tool to help assess the significance of BRCA1 variants.
Cusin Isabelle et al. Human genomics 2018 Jul 12(1) 36
(Posted: Jul 18, 2018 9AM)
Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge
I Sundin et al, Bioinformatics, July 2018
(Posted: Jul 02, 2018 8AM)
Next-generation Sequence-analysis Toolkit (NeST): A standardized bioinformatics framework for analyzing Single Nucleotide Polymorphisms in next-generation sequencing data
S Ravishankar et al, BioRXIV, June 2018
(Posted: Jun 16, 2018 10AM)
Genomic and Bioinformatics Approaches for Analysis of Genes Associated With Cancer Risks Following Exposure to Tobacco Smoking.
Al-Obaide Mohammed A I et al. Frontiers in public health 2018 84
(Posted: Apr 23, 2018 1PM)
Genomics Specialist Careers: Meet the Clinical Bioinformaticians
Video, Genomics Education Program, UK, 2018
(Posted: Apr 03, 2018 0PM)
Current Bioinformatics resources in combating infectious diseases.
Saeb Amr T M et al. Bioinformation 2018 (1) 31-35
(Posted: Mar 06, 2018 9AM)
GenIO: a phenotype-genotype analysis web server for clinical genomics of rare diseases.
Koile Daniel et al. BMC bioinformatics 2018 Jan 19(1) 25
(Posted: Jan 31, 2018 9AM)
Precision medicine needs pioneering clinical bioinformaticians.
Gómez-López Gonzalo et al. Briefings in bioinformatics 2017 Oct
(Posted: Nov 01, 2017 9AM)
Applying Family Analyses to Electronic Health Records to Facilitate Genetic Research.
Huang Xiayuan et al. Bioinformatics (Oxford, England) 2017 09
(Posted: Oct 30, 2017 8AM)
Circulating Tumor DNA as Biomarkers for Cancer Detection
X Han et al, Genomics, Proteomics and Bioinformatics, April 2017
(Posted: May 13, 2017 6AM)
All biology is computational biology
F Markowetz, PLOS Biology, March 2017
(Posted: Mar 18, 2017 2PM)
How bioinformatics tools are bringing genetic analysis to the masses
JM Perkel, Nature News, February 28, 2017
(Posted: Feb 28, 2017 3PM)
Bioinformatics Approaches for Fetal DNA Fraction Estimation in Noninvasive Prenatal Testing.
Peng Xianlu Laura et al. International journal of molecular sciences 2017 Feb (2)
(Posted: Feb 28, 2017 9AM)
DMDtoolkit: a tool for visualizing the mutated dystrophin protein and predicting the clinical severity in DMD.
Zhou Jiapeng et al. BMC bioinformatics 2017 Feb 18(1) 87
(Posted: Feb 08, 2017 9AM)
A primer on precision medicine informatics.
Sboner Andrea et al. Briefings in bioinformatics 2016 Jan 17(1) 145-53
(Posted: Nov 02, 2016 10AM)
Regulatory bioinformatics for food and drug safety.
Healy Marion J et al. Regulatory toxicology and pharmacology : RTP 2016 Oct 342-7
(Posted: Sep 05, 2016 7PM)
A research roadmap for next-generation sequencing informatics
RB Altman et al, Science Trans Med, April 20, 2016
(Posted: Apr 20, 2016 3PM)
Characterizing the Zika virus genome - A bioinformatics study.
Nandy Ashesh et al. Current computer-aided drug design 2016 Apr
(Posted: Mar 10, 2016 0AM)
Collaboration Paving Way for Large-Scale Computational Cancer Science
W Kibbe, National Cancer Institute
(Posted: Feb 23, 2016 9AM)
Single-cell Transcriptome Study as Big Data.
Yu Pingjian et al. Genomics, proteomics & bioinformatics 2016 Feb
(Posted: Feb 22, 2016 4PM)
Adapting bioinformatics curricula for big data
AC Greene et al. Topics in Bioinformatics, February 2016
(Posted: Feb 17, 2016 4PM)
Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams
K Shameer, Briefing in Bioinformatics, February 2016
(Posted: Feb 15, 2016 3PM)
The Road to Metagenomics: From Microbiology to DNA Sequencing Technologies and Bioinformatics.
Escobar-Zepeda Alejandra et al. Frontiers in genetics 2015 348
(Posted: Feb 15, 2016 3PM)
Translational Bioinformatics and Clinical Research (Biomedical) Informatics.
Sirintrapun S Joseph et al. Clinics in laboratory medicine 2016 Mar (1) 153-81
(Posted: Feb 15, 2016 3PM)
The Adapting Mind in the Genomic Era.
Fieder Martin et al. Frontiers in psychology 2016 78
(Posted: Feb 15, 2016 3PM)
Facing the challenges of multiscale modelling of bacterial and fungal pathogen-host interactions.
Schleicher Jana et al. Briefings in functional genomics 2016 Feb
(Posted: Feb 15, 2016 3PM)
Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud.
Afgan Enis et al. PloS one 2015 (10) e0140829
(Posted: Nov 05, 2015 8PM)
Information and informatics literacies of first-year medical students.
Richardson Joshua E et al. Journal of the Medical Library Association : JMLA 2015 Oct (4) 198-202
(Posted: Oct 30, 2015 2PM)
Integrated Bioinformatics, Environmental Epidemiologic and Genomic Approaches to Identify Environmental and Molecular Links between Endometriosis and Breast Cancer.
Roy Deodutta et al. International journal of molecular sciences (10) 25285-25322
(Posted: Oct 30, 2015 2PM)
Systems biology approaches to adverse drug effects: the example of cardio-oncology.
Brown Sherry-Ann et al. Nature reviews. Clinical oncology 2015 Oct
(Posted: Oct 30, 2015 2PM)
Why Bioinformatics Analysis Is Not Free
D Koboldt, MassGenomics, October 29, 2015
(Posted: Oct 30, 2015 2PM)
CATCHing putative causative variants in consanguineous families.
Santoni Federico Andrea et al. BMC bioinformatics 2015 (1) 310
(Posted: Oct 15, 2015 8AM)
Introduction to Bioinformatics
Genomics Education Program, UK
(Posted: Sep 01, 2015 1PM)
Bioinformatics in Public Health Fellowship Program
APHL-sponsored training in CDC?s infectious disease labs
(Posted: Jul 20, 2015 11AM)
2015 Rapid NGS Bioinformatic Pipelines for Enhanced Molecular Epidemiologic Investigation of Pathogens
American Society for Microbioloby. Washington, DC, Sept 24-27, 2015.
(Posted: Jul 17, 2015 4PM)
Global Microbial Identifier
(Posted: Jul 17, 2015 4PM)
No more hidden solutions in bioinformatics.
Vihinen Mauno et al. Nature 2015 May 21. (7552) 261
(Posted: Jul 17, 2015 4PM)
Unified representation of genetic variants.
Tan Adrian et al. Bioinformatics 2015 Jul 1. (13) 2202-4
(Posted: Jul 17, 2015 4PM)
Good laboratory practice for clinical next-generation sequencing informatics pipelines.
Gargis Amy S et al. Nat. Biotechnol. 2015 Jul 8. (7) 689-93
(Posted: Jul 17, 2015 4PM)
Estimating copy numbers of alleles from population-scale high-throughput sequencing data.
Mimori Takahiro et al. BMC Bioinformatics 2015 S4
(Posted: May 26, 2015 1PM)
Bioinformatics analysis and genetic diversity of the poliovirus.
Liu Yanhan et al. J. Med. Microbiol. 2014 Dec (Pt 12) 1724-31
(Posted: May 23, 2015 8PM)
Integration of somatic mutation, expression and functional data reveals potential driver genes predictive of breast cancer survival.
Suo Chen et al. Bioinformatics 2015 Mar 24.
(Posted: May 22, 2015 6PM)
No more hidden solutions in bioinformatics
Precision medicine cannot advance without full disclosure of how commercial genome sequencing and interpretation software Mauno Vihinen, Nature News, May 20, 2015
(Posted: May 20, 2015 3PM)
How can bioinformatics and toxicogenomics assist the next generation of research on physical exercise and athletic performance.
Kerksick Chad M et al. J Strength Cond Res 2015 Jan (1) 270-8
(Posted: May 16, 2015 7AM)
Finding a needle in the haystack: leveraging bioinformatics to identify a functional genetic risk factor for sepsis death.
Meyer Nuala J et al. Crit. Care Med. 2015 Jan (1) 242-3
(Posted: May 14, 2015 8AM)
Three minimal sequences found in Ebola virus genomes and absent from human DNA.
Silva Raquel M et al. Bioinformatics 2015 Apr 2.
(Posted: May 05, 2015 0PM)
What is Public Health Informatics?
Health informatics, healthcare informatics or medical informatics is the intersection of information science, computer science and health care. From Johns Hopkins University
(Posted: Apr 16, 2015 6AM)
Systems biology approaches for advancing the discovery of effective drug combinations.
Ryall Karen A et al. J Cheminform 2015 7
(Posted: Apr 16, 2015 6AM)
Clinical decision support systems for improving diagnostic accuracy and achieving precision medicine.
Castaneda Christian et al. J Clin Bioinforma 2015 4
(Posted: Apr 16, 2015 6AM)
Convergent evolution of health information management and health informatics: a perspective on the future of information professionals in health care.
Gibson C J et al. Appl Clin Inform 2015 (1) 163-84
(Posted: Apr 16, 2015 6AM)
What is Public Health Informatics?
from the American Medical Informatics Association
(Posted: Apr 16, 2015 6AM)
Toward Precision Medicine-Building scale in biomedical informatics
Harvard Magazine, April 2015
(Posted: Apr 16, 2015 6AM)
What is the Science of Informatics
from the American Medical Informatics Association
(Posted: Apr 16, 2015 6AM)
Biological Databases for Human Research.
Zou Dong et al. Genomics Proteomics Bioinformatics 2015 Feb (1) 55-63
(Posted: Apr 14, 2015 0PM)
Adapting bioinformatics curricula for big data.
Greene Anna C et al. Brief. Bioinformatics 2015 Mar 30.
(Posted: Apr 14, 2015 0PM)
Data-intensive analysis of HIV mutations.
Ozahata Mina et al. BMC Bioinformatics 2015 Feb 5. (1) 35
(Posted: Mar 30, 2015 6AM)
Possible Biomarkers for the Early Detection of HIV-associated Heart Diseases: A Proteomics and Bioinformatics Prediction.
Rasheed Suraiya et al. Comput Struct Biotechnol J 2015 145-52
(Posted: Mar 30, 2015 6AM)
Identification of genes and pathways involved in kidney renal clear cell carcinoma.
Yang William et al. BMC Bioinformatics 2014 S2
(Posted: Mar 23, 2015 9AM)
Web Resources for Pharmacogenomics.
Zhang Guoqing et al. Genomics Proteomics Bioinformatics 2015 Feb 19.
(Posted: Mar 11, 2015 10AM)
CDC Public Health Informatics Fellowship Program
(Posted: Feb 25, 2015 0PM)
CDC Advanced Molecular Detection Initiative
Using combined talents of experts in epidemiology, laboratory science, and bioinformatics
(Posted: Feb 25, 2015 0PM)
Next Generation Sequencing: Standardization of Clinical Testing (Nex-StoCT) Working Groups
(Posted: Feb 25, 2015 0PM)
Potential of Advanced Molecular Detection and Response at CDC
(Posted: Feb 25, 2015 0PM)
Identification of a Human Papillomavirus-Associated Oncogenic miRNA Panel in Human Oropharyngeal Squamous Cell Carcinoma Validated by Bioinformatics Analysis of The Cancer Genome Atlas.
Miller Daniel L et al. Am. J. Pathol. 2015 Jan 5.
(Posted: Feb 13, 2015 11AM)
Precision Medicine Trials for Cancer: A New Era
(Posted: Jan 11, 2014 11AM)
For Some Children with Cancer, Genomic Information May Help Guide Treatment Decisions
(Posted: Jan 11, 2014 11AM)
Proceedings of the 14th Annual UT-KBRIN Bioinformatics Summit 2015.
BMC bioinformatics 2015 Oct I1-P21
(Posted: Jan 01, 2014 0AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Mar 27, 2024
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