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Hot Topics of the Day|PHGKB
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10/13/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

From race-based to race-conscious medicine: how anti-racist uprisings call us to act.
Cerdeña Jessica P et al. Lancet (London, England) 2020 Oct (10257) 1125-1128

Research in clinical medicine and epidemiology requires explicit hypotheses; however, hypotheses involving race are frequently implicit and circular, relying on conventional wisdom that Black and Brown people are genetically distinct from White people.

Scientists have a powerful new tool for controlling the coronavirus: Its own genetic code.
B Dennis et al, Washington Post, October 12, 2020

For all six British patients, genome sequencing revealed they had been infected by almost identical sub-strains of SARS-CoV-2, the virus that causes covid-19. Epidemiologists soon determined that all six had visited the same outpatient dialysis clinic on the same day of the week. Many had ridden in the same small transport van that regularly brought patients for treatment from across the surrounding area.

COVID-19 Susceptibility and Severity Risks in a Survey of Over 500,000 People
SC Knight et al, MEDRXIV, October 12, 2020

Social Distancing with Movement Restrictions and the Effective Replication Number of COVID-19: Multi-Country Analysis Based on Phone Mobility Data
MO Setti et al, MEDRXIV, October 12, 2020

Chest X-ray image analysis and classification for COVID-19 pneumonia detection using Deep CNN
T Gao, MEDRXIV, October 12, 2020

Machine learning based prognostic model and mobile application software platform for predicting infection susceptibility of COVID-19 using health care data
S Raveendran et al, MEDRXIV, October 12, 2020

From public health perspectives of COVID-19 pandemic, accurate estimates of infection severity of individuals are extremely valuable for informed decision making and targeted response to an emerging pandemic. This paper presents machine learning based prognostic model for providing early warning to the individuals for COVID-19 infection using health care data.

Genomic evidence for reinfection with SARS-CoV-2: a case study
RL Tillet et al, Lancet Inf Diseases, October 12, 2020

A 25-year-old man who was a resident of Washoe County in the US state of Nevada presented to health authorities on two occasions with symptoms of viral infection. The patient had two positive tests for SARS-CoV-2, separated by two negative tests done during follow-up. Genomic analysis of SARS-CoV-2 showed genetically significant differences between each variant associated with each instance of infection.

Viewing the covid-19 pandemic through the lens of social media
G McKenzie, BMJ Blog, October 12, 2020

More Companies Are Using Technology To Monitor For Coronavirus In The Workplace
J Baubien, NPR, October 13, 2020

Heritable Genome Editing Not Ready for the Clinic, Panel Says
J Abbasi, JAMA, October 13, 2020

The report focuses on scientific considerations and lays out a “responsible pathway for clinical use” of heritable human genome editing. The group also called for the formation of an international scientific advisory panel of independent experts that can assess any technique’s safety and effectiveness before it’s used clinically.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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