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Hot Topics of the Day|PHGKB
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07/26/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

PACIFIC: A lightweight deep-learning classifier of SARS-CoV-2 and co-infecting RNA viruses
PA Mateos et al, BIORXIV, July 24, 2020

Host transcriptional responses and SARS-CoV-2 isolates from the nasopharyngeal samples of Bangladeshi COVID-19 patients
A Islam et al, BIORXIV, July 24, 2020

A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material
JN Rauch et al, BIORXIV, July 24, 2020

Freshwater monitoring by nanopore sequencing
L Urban et al, BIORXIV, July 25, 2020

Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2
J Kim et al, BIORXIV, July 25, 2020

Why COVID-19 models should incorporate the network of social interactions
HA Herrmann et al, MEDRXIV< July 26, 2020

Evidence of gender bias in the diagnosis and management of COVID-19 patients: A Big Data analysis of Electronic Health Records
J Ancochea et al, MEDRXIV, July 26, 2020

Viral RNA level, serum antibody responses, and transmission risk in discharged COVID-19 patients with recurrent positive SARS-CoV-2 RNA test results: a population-based observational cohort study
C Yang et al, MEDRXIV< July 26, 2020

Anatomy of digital contact tracing: role of age, transmission setting, adoption and case detection
JA Moreno Lopez et al, MEDRXIV, July 25, 2020

Big Data and Collaboration Seek to Fight COVID-19
E Yazinski, The Scientist, July 21, 2020

Researchers try unprecedented data sharing and cooperation to understand COVID-19—and develop a model for diseases beyond the coronavirus pandemic.

Genomics and epidemiological surveillance
SW Low et al, Nat Rev Micro, July 25, 2020

The timely detection and surveillance of infectious diseases and responses to pandemics are crucial but challenging. Whole-genome sequencing (WGS) is a common tool for pathogen identification and tracking, establishing transmission routes and outbreak control.

Outcome measures based on digital health technology sensor data: data- and patient-centric approaches
KI Taylor et al, NPJ Digital Medicine, July 2020

We describe two roadmaps which were developed to generate outcome measures based on DHTT data: one using a data-centric approach and the second a patient-centric approach. The data-centric approach to develop digital outcome measures summarizes those sensor features maximally sensitive to the concept of interest.

Inherited cardiac arrhythmias
PJ Shwartz et al, Nat Rev Dis Primers, July 2020

The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome, catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome. These rare diseases are often the underlying cause of sudden cardiac death in young individuals and result from mutations in several genes encoding ion channels or proteins involved in their regulation.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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