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Hot Topics of the Day|PHGKB
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07/24/2022

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Predicting Firearm Suicide-Small Steps Forward With Big Data.
Betz Marian E et al. JAMA network open 2022 7 (7) e2223758

Machine Learning Analysis of Handgun Transactions to Predict Firearm Suicide Risk.
Laqueur Hannah S et al. JAMA network open 2022 7 (7) e2221041

Can handgun purchasing records, coupled with machine learning techniques, be used to forecast firearm suicide risk? In this prognostic study of nearly 2 million individuals with handgun transaction records, among transactions classified in the riskiest 5%, close to 40% were associated with a purchaser who died by firearm suicide within 1 year. Among the small number of transactions with a random forest score of 0.95 and above, more than two-thirds were affiliated with a purchaser who died by firearm suicide within 1 year (24 of 35).

A digital pathway for genetic testing in UK NHS patients with cancer: BRCA-DIRECT randomised study internal pilot.
Torr Bethany et al. Journal of medical genetics 2022 7

We designed a rapid, digital pathway, supported by a genetics specialist hotline, for delivery of germline testing of BRCA1/BRCA2/PALB2 (BRCA-testing), integrated into routine UK NHS breast cancer care. We piloted the pathway, as part of the larger BRCA-DIRECT study, in 130 unselected patients with breast cancer and gathered preliminary data from a randomized comparison of delivery of pretest information digitally (fully digital pathway) or via telephone consultation with a genetics professional (partially digital pathway). Uptake of genetic testing was 98.4%, with good satisfaction reported for both the fully and partially digital pathways. Similar outcomes were observed in both arms regarding patient knowledge score and anxiety.


Disclaimer: Articles listed in Hot Topics of the Day are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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