Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content


Hot Topics of the Day|PHGKB
Search PHGKB:

04/02/2021

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

Sign up MyPHGKB to receive the daily hot topic email alert.

Search Archive:
Archived Hot Topics of the Day By Date

Data-Driven Surveillance: Effective Collection, Integration, and Interpretation of Data to Support Decision Making.
Dórea Fernanda C et al. Frontiers in veterinary science 2021 8633977

An increasing number of new data sources, including many not originally collected for health purposes, are now being used for epidemiological inference and contextualization. Combining evidence from multiple data sources presents significant challenges, but discussions around this subject often confuse issues of data access and privacy, with the actual technical challenges of data integration and interoperability.

Impact of diabetes on coronary severity and cardiovascular outcomes in patients with heterozygous familial hypercholesterolaemia.
Liu Ming-Ming et al. European journal of preventive cardiology 2021

Type 2 diabetes mellitus (T2DM) is an independent risk factor for cardiovascular disease. However, the association between T2DM and coronary artery disease (CAD) in patients with heterozygous familial hypercholesterolaemia (HeFH) has not been thoroughly evaluated. Our study aimed to assess the effect of T2DM on CAD severity and hard cardiovascular endpoints in a HeFH cohort of 432 patients.

Mainstreaming informed consent for genomic sequencing: A call for action.
Bunnik Eline M et al. European journal of cancer (Oxford, England : 1990) 2021 148405-410

This paper outlines what mainstream oncologists may learn from the ethical tradition of informed consent for genomic sequencing, as developed within clinical genetics. It argues that mainstream informed consent practices should focus on preparing patients for three types of unsolicited outcomes, briefly and effectively.

Socioeconomic impacts of COVID-19 in low-income countries
A Josephson, et al, Nature Human Behavior, March 31, 2021

We used longitudinal household survey data from Ethiopia, Malawi, Nigeria and Uganda, originating from pre-COVID-19 face-to-face household surveys plus phone surveys implemented during the pandemic. We estimate that 256 million individuals—77% of the population—live in households that have lost income during the pandemic. Attempts to cope with this loss are exacerbated by food insecurity and an inability to access medicine and staple foods.

COVID-19 pandemic and health-care disruptions: count the most vulnerable
J Kumar, Lancet Global Health, March 31, 2021

COVID-19 vaccines for patients with haematological conditions
C Sun, Lancet Hematological Diseases, March 31, 2021

The trajectory of COVID-19 in patients with benign hematological conditions such as haemoglobinopathy, haemophilia, pre-existing arterial or venous thromboembolism, and autoimmune cytopenia is relatively unknown, but as in the general population, is influenced by age and comorbidities.

A method for detection of SARS-CoV-2 RNA in healthy human stool: a validation study
MP Corryel et al, Lancet Microbe, March 31, 20201


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
TOP