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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
Should COVID vaccines be yearly? Proposal divides US scientists
M Kozlov, Nature, January 27, 2023
(Posted: Jan 27, 2023 9AM)
mRNA revolutionized the race for a Covid-19 vaccine. Could cancer be next?
J Wosen, Stat News, November 21, 2022
(Posted: Nov 21, 2022 7AM)
Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines - United States, October 2022.
Rosenblum Hannah G et al. MMWR. Morbidity and mortality weekly report 2022 11 (45) 1436-1441
(Posted: Nov 11, 2022 6AM)
After Giving Up on Cancer Vaccines, Doctors Start to Find Hope
G Kolata, NY Times, October 10, 2022
(Posted: Oct 10, 2022 11AM)
CDC Recommends the First Updated COVID-19 Booster
CDC, September 1, 2022
(Posted: Sep 02, 2022 9AM)
Interim Recommendations of the Advisory Committee on Immunization Practices for Use of Moderna and Pfizer-BioNTech COVID-19 Vaccines in Children Aged 6 Months–5 Years — United States, June 2022
KE Fleming-Dutra et al, MMWR, June 28, 2022
(Posted: Jun 29, 2022 0PM)
Technical Guide for Public Health Departments: Reporting and Analyzing COVID-19 Cases by Vaccination Status
CDC, June 23, 2022
(Posted: Jun 25, 2022 11AM)
CDC Recommends Moderna COVID-19 Vaccine for Children and Adolescents
CDC, June 24, 2022
(Posted: Jun 25, 2022 11AM)
CDC Recommends COVID-19 Vaccines for Young Children
CDC, June 18, 2022
(Posted: Jun 18, 2022 7PM)
COVID-19 Vaccination Coverage, by Race and Ethnicity — National Immunization Survey Adult COVID Module, United States, December 2020–November 2021
JL Kriss et al, MMWR, June 10, 2022
(Posted: Jun 10, 2022 7AM)
Analysis of immunization time, amplitude, and adverse events of seven different vaccines against SARS-CoV-2 across four different countries.
ME Romero-Ibarguengoitia et al, MEDRXIV, May 4, 2022
(Posted: May 04, 2022 4PM)
The Advisory Committee on Immunization Practices’ Recommendation for Use of Moderna COVID-19 Vaccine in Adults Aged ≥18 Years and Considerations for Extended Intervals for Administration of Primary Series Doses of mRNA COVID-19 Vaccines — United States, February 2022
M Wallace et al, MMWR, March 18, 2022
(Posted: Mar 18, 2022 7AM)
Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) Variant
N Andrews e al, NEJM, March 2, 2022
(Posted: Mar 02, 2022 5PM)
Boosting immunity to Omicron
X Shen, Nature Medicine, February 24, 2022
(Posted: Feb 25, 2022 9AM)
Durability of Omicron-neutralizing serum activity following mRNA booster immunization in elderly individuals
K Vanshylla et al, MEDRXIV, February 2, 2022
(Posted: Feb 03, 2022 0PM)
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil Paul R et al. Nature medicine 2022 1
(Posted: Jan 29, 2022 10AM)
CDC Expands Booster Shot Eligibility and Strengthens Recommendations for 12-17 Year Olds
CDC, January 5, 2022
(Posted: Jan 06, 2022 7AM)
Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021
K Lutrik et al, MMWR, December 30, 2021
(Posted: Dec 31, 2021 6AM)
CDC endorses ACIP’s updated COVID-19 vaccine recommendations
CDC, December 16, 2021
(Posted: Dec 17, 2021 6AM)
Effectiveness of COVID-19 vaccines against the Omicron (B.1.1.529) variant of concern
N Andrews et al, MEDRXIV, December 14, 2021
(Posted: Dec 15, 2021 7AM)
mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant
H Gruell et al, MEDRXIV, December 14, 2021
(Posted: Dec 14, 2021 1PM)
V-safe and Registry Monitoring People Who Report Pregnancy
CDC, December 7, 2021
(Posted: Dec 08, 2021 8AM)
CDC Expands Eligibility for COVID-19 Booster Shots to All Adults
CDC, November 19, 2021
(Posted: Nov 21, 2021 10AM)
Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial
R Lazarus et al, The Lancet, November 11, 2021
(Posted: Nov 13, 2021 6AM)
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine in Children Aged 5–11 Years — United States, November 2021
KR Woodworth et al, MMWR, November 5, 2021
(Posted: Nov 06, 2021 9AM)
CDC Recommends Pediatric COVID-19 Vaccine for Children 5 to 11 Years
CDC, November 2, 2021
(Posted: Nov 03, 2021 0PM)
If You’ve Had Covid, Do You Need the Vaccine? So-called natural immunity varies from patient to patient, scientists say. Immunization is still the best choice after recovering from the disease.
A Mandavilli, NY Times, October 12, 2021
(Posted: Oct 12, 2021 1PM)
Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors
RT Shroff et al, Nature Medicine, September 30, 2021
(Posted: Oct 01, 2021 6AM)
Use of Pfizer-BioNTech COVID-19 Vaccine in Persons Aged ≥16 Years: Recommendations of the Advisory Committee on Immunization Practices — United States, September 2021
K Dooling et al, MMWR, September 21, 2021
(Posted: Sep 21, 2021 4PM)
Effectiveness of COVID-19 Vaccines Against SARS-CoV-2 Infection During a Delta Variant Epidemic Surge in Multnomah County, Oregon, July 2021
RS Barlow et al, MEDRXIV, September 3, 2021
(Posted: Sep 04, 2021 10AM)
Prevalence of Allergic Reactions After Pfizer-BioNTech COVID-19 Vaccination Among Adults With High Allergy Risk
R Shavit et al, JAMA Network Open, August 31, 2021
(Posted: Sep 01, 2021 7AM)
Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States
CDC Update, August 31, 2021
(Posted: Sep 01, 2021 7AM)
High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge: a case for continued use of masks post-vaccination
R Ujjainiya et al, MEDRXIV, August 28, 2021
(Posted: Aug 29, 2021 6AM)
Joint Statement from HHS Public Health and Medical Experts on COVID-19 Booster Shots
HHS, August 18, 2021
(Posted: Aug 18, 2021 11AM)
Use of COVID-19 Vaccines After Reports of Adverse Events Among Adult Recipients of Janssen (Johnson & Johnson) and mRNA COVID-19 Vaccines (Pfizer-BioNTech and Moderna): Update from the Advisory Committee on Immunization Practices — United States, July 2021
HG Rosenblum et al, MMWR, August 2021
(Posted: Aug 15, 2021 3PM)
BNT162b2-Elicited Neutralization against New SARS-CoV-2 Spike Variants.
Liu Yang et al. The New England journal of medicine 2021 5 (5) 472-474
(Posted: Jul 29, 2021 8AM)
Quarter-dose of Moderna COVID vaccine still rouses a big immune response
E Dolgin, Nature News, July 2021
(Posted: Jul 16, 2021 7AM)
Use of mRNA COVID-19 Vaccine After Reports of Myocarditis Among Vaccine Recipients: Update from the Advisory Committee on Immunization Practices — United States, June 2021
JW Gargano et al, CDC MMWR< July 6, 2021
(Posted: Jul 06, 2021 0PM)
Myocarditis Occurring After Immunization With mRNA-Based COVID-19 Vaccines.
Shay David K et al. JAMA cardiology 2021 6
(Posted: Jun 30, 2021 7AM)
Long-lasting neutralizing antibody responses in SARS-CoV-2 seropositive individuals are robustly boosted by immunization with the CoronaVac and BNT162b2 vaccines
NA Muena et al MEDRXIV, May 18, 2021
(Posted: May 19, 2021 8AM)
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine in Adolescents Aged 12–15 Years — United States, May 2021
M Wallace et al, MMWR, May 14, 2021
(Posted: May 14, 2021 3PM)
CDC Director Statement on Pfizer’s Use of COVID-19 Vaccine in Adolescents Age 12 and Older
CDC, May 12, 2021
(Posted: May 13, 2021 3PM)
Pfizer COVID vaccine protects against worrying coronavirus variants- Data from Qatar provide strongest evidence yet that COVID-19 vaccines can stop strains thought to pose a threat to immunization efforts.
E Callaway, Nature, May 6, 2021
(Posted: May 07, 2021 10AM)
Interplay between Emerging SARS-CoV-2 Variants and Pandemic Control.
Neuzil Kathleen M et al. The New England journal of medicine 2021 5
(Posted: May 06, 2021 7AM)
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
L Stamatatos et al, Science, March 27, 2021
(Posted: Mar 26, 2021 8AM)
Approaches for Optimal Use of Different COVID-19 Vaccines - Issues of Viral Variants and Vaccine Efficacy
JP Moore, JAMA, March 4, 2021
(Posted: Mar 04, 2021 1PM)
SARS-CoV-2 Vaccines
CB Creech et al, JAMA, February 26, 2021
(Posted: Feb 27, 2021 7AM)
Could mixing COVID vaccines boost immune response? Combining different coronavirus shots could speed immunization campaigns — and even boost immune response.
H Ledford, Nature News, February 4, 2021
(Posted: Feb 07, 2021 6AM)
SARS-CoV-2 B.1.1.7 escape from mRNA vaccine-elicited neutralizing antibodies
D Collier et al, MEDRXIV, February 2, 2021
(Posted: Feb 02, 2021 10AM)
The effectiveness of the first dose of BNT162 b 2 vaccine in reducing SARS-CoV-2 infection 13-24 days after immunization: real-world evidence
G Chodcik et al, MEDRXIV, January 29, 2021
(Posted: Jan 29, 2021 9AM)
When Vaccine is Limited, Who Should Get Vaccinated First?
CDC, January 8, 2021
(Posted: Jan 09, 2021 0PM)
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Moderna COVID-19 Vaccine — United States, December 2020
SE Oliver et al, MMWR, December 20, 2020
(Posted: Dec 21, 2020 7AM)
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine — United States, December 2020
SE Oliver et al, MMWR, December 13, 2020
(Posted: Dec 14, 2020 6AM)
The Advisory Committee on Immunization Practices' Ethical Principles for Allocating Initial Supplies of COVID-19 Vaccine - United States, 2020.
McClung Nancy et al. MMWR. Morbidity and mortality weekly report 2020 Nov (47) 1782-1786
(Posted: Nov 27, 2020 10AM)
All eyes on a hurdle race for a SARS-CoV-2 vaccine
C Gaebler et al, Nature News, October 19, 2020
(Posted: Oct 20, 2020 1PM)
An Inactivated Virus Candidate Vaccine to Prevent COVID-19
MJ Mulligan, JAMA, August 13, 2020
(Posted: Aug 13, 2020 11AM)
AI Can Help Us Fight Infectious Diseases In A More Effective Way
M Colangelo et al, Forbes, March 27, 2020
(Posted: Mar 28, 2020 8AM)
There Are Vaccines You Need as an Adult
CDC, 2019
(Posted: Aug 08, 2019 9AM)
Maternal Vaccines: Part of a Healthy Pregnancy
CDC, 2019
(Posted: Aug 08, 2019 9AM)
Vaccines: Life savers against infectious diseases
Wellcome Trust Sanger Blog, August 2, 2019
(Posted: Aug 03, 2019 0PM)
Preventive care services and health behaviors in children with fragile X syndrome.
Gilbertson Kendra E et al. Disability and health journal 2019 May
(Posted: Jul 19, 2019 10AM)
Common Genetic Variations Associated with the Persistence of Immunity following Childhood Immunization.
O'Connor Daniel et al. Cell reports 2019 Jun (11) 3241-3253.e4
(Posted: Jun 18, 2019 10AM)
Why some people don’t respond to childhood vaccines—and how our DNA could fix it
N Akpan, PBS< June 17, 2019
(Posted: Jun 18, 2019 10AM)
Genetic approach towards a vaccine against malaria.
Garrido-Cardenas Jose Antonio et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2018 Jun
(Posted: Aug 03, 2018 0PM)
DNA and mRNA vaccination against allergies.
Scheiblhofer Sandra et al. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2018 Jul
(Posted: Aug 03, 2018 0PM)
Protect Your Baby with Immunization
(Posted: Apr 23, 2018 3PM)
A world without bacterial meningitis: how genomic epidemiology can inform vaccination strategy.
Rodrigues Charlene M C et al. F1000Research 2018 401
(Posted: Apr 23, 2018 3PM)
National Immunization Week
2018 DIGITAL MEDIA TOOLKIT
(Posted: Apr 23, 2018 3PM)
Global Introduction of New Vaccines: Delivering More to More
CDC Grand Rounds, Mar 20, 2018
(Posted: Mar 20, 2018 11AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
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