Archive
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
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Archived Hot Topics of the Day By Date
Data science and health economics in precision public health
MA Talias et al, Frontiers in Public Health, December, 2022
(Posted: Dec 07, 2022 8AM)
Data-enabled responses to pandemics: policy lessons from COVID-19.
Dhami Sangeeta et al. Nature medicine 2022 10
(Posted: Oct 22, 2022 0PM)
The complexity of diagnosing rare disease: An organizing framework for outcomes research and health economics based on real-world evidence.
Hayeems Robin Z et al. Genetics in medicine : official journal of the American College of Medical Genetics 2021 12 (3) 694-702
(Posted: Apr 22, 2022 0PM)
Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines
MO Barton, The Lancet Global Health, November 2, 2021
(Posted: Nov 03, 2021 11AM)
Developing an Economic and Policy Research Agenda for Blood Biomarkers of Neurodegenerative Diseases
JJ Arias et al, JAMA Health Forum, July 16, 2021
(Posted: Jul 17, 2021 7AM)
Cost or price of sequencing? Implications for economic evaluations in genomic medicine
SD Grosse et al, Genetics in Medicine, June 10, 2021
(Posted: Jun 10, 2021 10AM)
New publications in health economics and genomics 8th June 2021
J Buchanan, Health Economics and Genomics, June 2021
(Posted: Jun 09, 2021 7AM)
Expanding evidence leads to new pharmacogenomics payer coverage
PE Empey et al, Genetics in Medicine, February 24, 2021
(Posted: Feb 25, 2021 7AM)
Using Lorenz Curves to Measure Racial Inequities in COVID-19 Testing
A Mody et al, JAMA Network Open, January 8, 2020
(Posted: Jan 08, 2021 11AM)
Efficacy and costs of spinal muscular atrophy drugs
JJ Darrow et al, Sci Trans Med, November 11, 2020
(Posted: Nov 12, 2020 8AM)
Economic value of exome sequencing for suspected monogenic disorders
BS Ferket et al, Genetics in Medicine, June 30, 2020
(Posted: Jul 01, 2020 8AM)
Cost-effectiveness of targeted screening for the identification of patients with atrial fibrillation: Evaluation of a machine learning risk prediction algorithm.
Hill Nathan R et al. Journal of medical economics 2019 Dec 1
(Posted: Jan 02, 2020 9AM)
Exome sequencing: value is in the eye of the beholder
SD Grosse et al, Genetics in Medicine, October 14, 2019
(Posted: Oct 14, 2019 4PM)
Application of Economic Evaluation to Assess Feasibility for Reimbursement of Genomic Testing as Part of Personalized Medicine Interventions.
Simeonidis Stavros et al. Frontiers in pharmacology 2019 10830
(Posted: Aug 27, 2019 6PM)
This Drug Will Save Children’s Lives. It Costs $2 Million.
NY Times editorial board, August 13, 2019
(Posted: Aug 14, 2019 8AM)
The complete costs of genome sequencing: a microcosting study in cancer and rare diseases from a single center in the United Kingdom.
Schwarze Katharina et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Jul
(Posted: Jul 31, 2019 10AM)
Long-term economic impacts of exome sequencing for suspected monogenic disorders: diagnosis, management, and reproductive outcomes.
Schofield Deborah et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 May
(Posted: Jun 07, 2019 10AM)
The costliest drug on the planet will treat infants with rare disease. The market fight focused on cost and safety is just getting started.
C Rowland, NY Times, May 15, 2019
(Posted: May 20, 2019 8AM)
Accounting for Capacity Constraints in Economic Evaluations of Precision Medicine: A Systematic Review.
Wright Stuart J et al. PharmacoEconomics 2019 May
(Posted: May 20, 2019 8AM)
Economics of Genetic Testing for Diabetes.
Naylor Rochelle et al. Current diabetes reports 2019 Mar 19(5) 23
(Posted: Apr 03, 2019 9AM)
Value of genetic testing in the prevention of coronary heart disease events
Y Hynninen et al, PLOS One, January 2019
(Posted: Jan 20, 2019 8AM)
Estimating the burden and economic impact of pediatric genetic disease
N Gonzaludo et al, Genetics in Medicine, December 19, 2018
(Posted: Dec 20, 2018 8AM)
High price of precision medicine forces cancer patients to make agonizing choices
L Szabo, USA Today, October 26, 2018
(Posted: Oct 26, 2018 0PM)
Evaluating the Outcomes Associated with Genomic Sequencing
J Buchanan, Health Economics and Genomics Blog, October 10, 2018
(Posted: Oct 10, 2018 9AM)
Direct health-care costs for children diagnosed with genetic diseases are significantly higher than for children with other chronic diseases.
Marshall Deborah A et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Sep
(Posted: Sep 25, 2018 11AM)
Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project.
Christensen Kurt D et al. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2018 21(9) 1054-1061
(Posted: Sep 19, 2018 9AM)
The True Cost of Whole Genome Sequencing
Genomes2People, Medium, September 12, 2018
(Posted: Sep 13, 2018 4PM)
Would Routine Genomic Testing For Cancer And Heart Risk Make Economic Sense?
A Weintraub, Forbes, July 30, 2018
(Posted: Aug 01, 2018 8AM)
The Price of Precision: Genetic Testing and Drug Costs in America.
Rich Kelly et al. Genetic testing and molecular biomarkers 2018 Jul 22(7) 403-404
(Posted: Jul 25, 2018 8AM)
HERC database of health economics and genomics studies
HERC, Nuffield Department of Population Health, May 2018
(Posted: May 14, 2018 8AM)
Cost-effectiveness of Genome and Exome Sequencing in Children Diagnosed with Autism Spectrum Disorder.
Yuen Tracy et al. Applied health economics and health policy 2018 Apr
(Posted: Apr 18, 2018 10AM)
Value-based genomics.
Gong Jun et al. Oncotarget 2018 Mar 9(21) 15792-15815
(Posted: Apr 18, 2018 10AM)
Will Personalized Medicine Mean Higher Costs for Consumers?
M Geruso et al, Harvard Business Review, Mar 1, 2018
(Posted: Mar 02, 2018 10AM)
Economics of Pharmacogenetic-Guided Treatments: Underwhelming or Overstated?
Hughes Dyfrig A et al. Clinical pharmacology and therapeutics 2018 Feb
(Posted: Feb 21, 2018 10AM)
Cost-effectiveness of population based BRCA testing with varying Ashkenazi Jewish ancestry.
Manchanda Ranjit et al. American journal of obstetrics and gynecology 2017 Jul
(Posted: Jul 19, 2017 8AM)
Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.
Müller Dirk et al. The European journal of health economics : HEPAC : health economics in prevention and care 2017 Apr
(Posted: Apr 12, 2017 8AM)
Economic Evaluations of Thrombophilia Screening Prior to Prescribing Combined Oral Contraceptives: A Systematic and Critical Review.
Vernon Erin et al. Applied health economics and health policy 2017 Mar
(Posted: Mar 22, 2017 10AM)
How economics can shape precision medicines
AD Stern et al, Science, March 17, 2017
(Posted: Mar 16, 2017 5PM)
Prospective comparison of the cost-effectiveness of clinical whole-exome sequencing with that of usual care overwhelmingly supports early use and reimbursement
Z Stark et al, Genetics in Medicine, January 26, 2017
(Posted: Jan 26, 2017 11AM)
Health economics, genomics and the value of knowing
J Buchanan, January 5, 2016
(Posted: Jan 05, 2017 11AM)
Economic Evaluation of a Pharmacogenomics Test for Statin-Induced Myopathy in Cardiovascular High-Risk Patients Initiating a Statin.
Mitchell Dominic et al. Molecular diagnosis & therapy 2016 Oct
(Posted: Nov 02, 2016 10AM)
Challenges in the health economics of familial hypercholesterolemia.
Norman Richard et al. Current opinion in lipidology 2016 Oct
(Posted: Nov 02, 2016 10AM)
Is the $1000 Genome as Near as We Think? A Cost Analysis of Next-Generation Sequencing.
van Nimwegen Kirsten J M et al. Clinical chemistry 2016 Nov 62(11) 1458-1464
(Posted: Nov 02, 2016 10AM)
A Systematic Review of Health Economic Evaluations of Diagnostic Biomarkers.
Oosterhoff Marije et al. Applied health economics and health policy 2016 Feb 14(1) 51-65
(Posted: Nov 02, 2016 10AM)
Genetic markers as instrumental variables.
von Hinke Stephanie et al. Journal of health economics 2016 Jan 131-48
(Posted: Mar 19, 2016 0PM)
Genetic testing and economic evaluations: a systematic review of the literature.
D'Andrea Elvira et al. Epidemiologia e prevenzione 39(4 Suppl 1) 45-50
(Posted: Oct 28, 2015 9AM)
The Economics of Reproducibility in Preclinical Research
LP Freedman, et al. PLoS Biology, June 9, 2015
(Posted: Jun 09, 2015 3PM)
Insurance companies are slow to cover next-generation sequencing.
Chakradhar Shraddha et al. Nat. Med. 2015 Mar 5. (3) 204-5
(Posted: Mar 07, 2015 4PM)
Comparative effectiveness of next generation genomic sequencing for disease diagnosis: design of a randomized controlled trial in patients with colorectal cancer/polyposis syndromes.
Gallego Carlos J et al. Contemp Clin Trials 2014 Sep (1) 1-8
(Posted: Feb 14, 2015 7AM)
Is the "$1000 Genome" really $1000? Understanding the full benefits and costs of genomic sequencing.
Phillips Kathryn A et al. Technol Health Care 2015 Feb 6.
(Posted: Feb 14, 2015 7AM)
Genome sequencing: a systematic review of health economic evidence.
Frank Martin et al. Health Econ Rev 2013 (1) 29
(Posted: Feb 14, 2015 7AM)
How behavioral economics can help to avoid 'The last mile problem' in whole genome sequencing.
Blumenthal-Barby Jennifer S et al. Genome Med 2015 (1) 3
(Posted: Feb 14, 2015 7AM)
The cost-effectiveness of returning incidental findings from next-generation genomic sequencing.
Bennette Caroline S et al. Genet. Med. 2014 Nov 13.
(Posted: Feb 14, 2015 7AM)
The Cost-Effectiveness of Clinical Sequencing
Veenstra D et al. Institute of Medicine Discussion Paper, February 2015
(Posted: Feb 14, 2015 7AM)
Next Generation DNA Sequencing: A Review of the Cost Effectiveness and Guidelines
et al. Ottawa (ON):Canadian Agency for Drugs and Technologies in Health 2014 Feb 6.
(Posted: Feb 14, 2015 7AM)
Genomics, the data revolution, and health economics?the 2015 Astellas Innovation Debate
BMJ Blog Post, James Buchanan, February 2, 2015
(Posted: Feb 12, 2015 8AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Mar 27, 2024
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