Archive
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
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Archived Hot Topics of the Day By Date
'It's all gone': CAR-T therapy forces autoimmune diseases into remission.
Heidi Ledford et al. Nature 2023 12
(Posted: Dec 13, 2023 7AM)
Women’s Unseen Battle: Shining a Light on Lupus
CDC, June 2023
(Posted: Jun 12, 2023 9AM)
High risk of autoimmune diseases after COVID-19.
Chetan Sharma et al. Nat Rev Rheumatol 2023 4
(Posted: Apr 14, 2023 7AM)
How a pioneering diabetes drug offers hope for preventing autoimmune disorders
E Dolgin, Nature, February 15, 2023
(Posted: Feb 15, 2023 7AM)
Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs.
Jean-Laurent Casanova et al. The Journal of clinical investigation 2023 1 (3)
(Posted: Feb 05, 2023 11AM)
The Use of Cell-free DNA in Clinical Practice: Work in Progress
M Clyne et al, CDC Blog Post, December 14, 2022
(Posted: Dec 14, 2022 5PM)
Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach
D Charitou et al, J PGX Journal, September 29, 2022
(Posted: Sep 29, 2022 9AM)
Mystery hepatitis cases in kids linked to unexpected viral suspect
J Kaiser, Science, May 25, 2022
(Posted: Jul 29, 2022 10AM)
Inching closer to precision treatment for rheumatoid arthritis
LT Donlin, Nature Medicine, June 9, 2022
(Posted: Jun 10, 2022 6AM)
A Phenome Wide Association Study of Severe COVID-19 Genetic Risk Variants
JA Regan et al, MEDRXIV, December 11, 2021
(Posted: Dec 12, 2021 9AM)
Evidence Used to Update the List of Underlying Medical Conditions Associated with Higher Risk for Severe COVID-19
CDC Science Brief, October 14, 2021
(Posted: Oct 16, 2021 8AM)
Preventing type 1 diabetes in childhood.
Dayan Colin M et al. Science (New York, N.Y.) 2021 7 (6554) 506-510
(Posted: Jul 31, 2021 9AM)
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative, Nature, July 8, 2021
(Posted: Jul 08, 2021 0PM)
COVID-19 vaccines for patients with haematological conditions
C Sun, Lancet Hematological Diseases, March 31, 2021
(Posted: Apr 02, 2021 8AM)
Autoimmune anti-DNA antibodies predict disease severity in COVID-19 patients
C Gomes et al, MEDRXIV, January 4, 2021
(Posted: Jan 05, 2021 8AM)
Recurrent pregnancy loss
E Dimitriadis et al, Nature DIs Primers, December 2020
(Posted: Dec 21, 2020 7AM)
Risk of death among people with rare autoimmune diseases compared to the general population in England during the 2020 COVID-19 pandemic.
RJ Peach et al, MEDRXIV, November 22, 2020
(Posted: Nov 22, 2020 11AM)
Insight on Sex-Based Immunity Differences, With COVID-19 Implications.
Hampton Tracy et al. JAMA 2020 Oct (13) 1274
(Posted: Oct 07, 2020 7AM)
Inflammasome genetics and complex diseases: a comprehensive review
FP Fernandes et al, EJHG June 5, 2020
(Posted: Jun 06, 2020 6AM)
A systematic review of the applications of artificial intelligence and machine learning in autoimmune diseases
IS Stafford et al, NPJ Digital Medicine, March 9, 2020
(Posted: Mar 10, 2020 8AM)
Summary-data-based mendelian randomization reveals druggable targets for multiple sclerosis
BM Jacobs et al, BioRXIV preprints, January 25, 2020
(Posted: Jan 26, 2020 7AM)
Microbes and genes in heart failure
S Epelman, Science Magazine, November 2019
(Posted: Nov 16, 2019 7AM)
This med student was given last rites before finding a treatment that saved his life. His method could help millions
R Pryor, CNN, September 14, 2019
(Posted: Sep 15, 2019 8AM)
Study Tests Immunotherapy in People with Cancer and Autoimmune Diseases
NCI, August 26, 2019
(Posted: Aug 27, 2019 7AM)
Type 1 diabetes: Genetic risk reflected in gut microbiome
A Sandiou, Medical News Today, August 20, 2019
(Posted: Aug 21, 2019 8AM)
Cell-Free DNA as a Biomarker in Autoimmune Rheumatic Diseases.
Duvvuri Bhargavi et al. Frontiers in immunology 2019 502
(Posted: May 20, 2019 9AM)
Familial association of attention-deficit hyperactivity disorder with autoimmune diseases in the population of Sweden.
Li Xinjun et al. Psychiatric genetics 2018 Nov
(Posted: Nov 27, 2018 10AM)
Common Thread: Celiac diseases shared genetics and biology with other autoimmune disorders may lead the way to more treatments for all.
K Human, Genome Magazine, Spring 2016
(Posted: Apr 05, 2016 6PM)
Statin-Associated Autoimmune Myopathy
AL Mammen. NEJM, February 18, 2016
(Posted: Feb 22, 2016 0PM)
MHC Genes Linked to Autoimmune Disease.
Deitiker Philip et al. Critical reviews in immunology 2015 (3) 203-51
(Posted: Feb 15, 2016 2PM)
Epigenetic alterations underlying autoimmune diseases.
Aslani Saeed et al. Autoimmunity 2016 Jan 1-15
(Posted: Feb 15, 2016 2PM)
Genetics of autoimmune diseases; perspectives from genome-wide association studies.
Kochi Yuta et al. International immunology 2016 Feb
(Posted: Feb 15, 2016 2PM)
Autoimmune diseases connecting risk alleles with molecular traits of the immune system
MG Arcelus et al, Nature Reviews Genetics, February 15, 2016
(Posted: Feb 15, 2016 2PM)
Coeliac disease and autoimmune diseasegenetic overlap and screening
KEA Lundin et al. Nature Reviews Gastroenterology and Hepatology, September 2015
(Posted: Sep 30, 2015 7AM)
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
YR Li et al. Nature Medicine, August 24, 2015
(Posted: Aug 24, 2015 11AM)
Epigenomics of autoimmune diseases.
Gupta Bhawna et al. Immunol. Cell Biol. 2015 Mar (3) 271-6
(Posted: Aug 10, 2015 1PM)
Genetic variants of SLC11A1 are associated with both autoimmune and infectious diseases: systematic review and meta-analysis.
Archer N S et al. Genes Immun. 2015 Jun (4) 275-83
(Posted: Aug 10, 2015 1PM)
Mechanisms of human autoimmunity.
Rosenblum Michael D et al. J. Clin. Invest. 2015 Jun (6) 2228-33
(Posted: Aug 10, 2015 1PM)
The gut microbiome in autoimmunity: Sex matters.
Gomez Andres et al. Clin. Immunol. 2015 May 6.
(Posted: Aug 10, 2015 1PM)
Cardiovascular disease biomarkers across autoimmune diseases.
Ahearn Joseph et al. Clin. Immunol. 2015 Jul 11.
(Posted: Aug 10, 2015 1PM)
Genetics of autoimmune diseases: insights from population genetics.
Ramos Paula S et al. J. Hum. Genet. 2015 Jul 30.
(Posted: Aug 10, 2015 1PM)
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
TL Lenz et al. Nature Genetics, August 10, 2015
(Posted: Aug 10, 2015 1PM)
Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families
CF Kuo et al. JAMA Internal Medicine, July 20, 2015
(Posted: Jul 20, 2015 2PM)
Clinical implications of copy number variations in autoimmune disorders.
Yim Seon-Hee et al. Korean J. Intern. Med. 2015 May (3) 294-304
(Posted: May 26, 2015 1PM)
GIMAP GTPase Family Genes: Potential Modifiers in Autoimmune Diabetes, Asthma, and Allergy.
Heinonen Mirkka T et al. J. Immunol. 2015 May 11.
(Posted: May 23, 2015 9AM)
Autoimmune Disease in First-Degree Relatives and Spouses of Individuals With Celiac Disease.
Emilsson Louise et al. Clin. Gastroenterol. Hepatol. 2015 Jan 31.
(Posted: Apr 21, 2015 8AM)
CDC Information: SLE is an autoimmune disease in which the immune system makes antibodies to cells in the body leading to widespread inflammation and tissue damage.
(Posted: Feb 25, 2015 0PM)
Antiphospholipid Antibody Syndrome
From NHLBI health topic site
(Posted: Jan 11, 2014 11AM)
Hepatitis
(Posted: Jan 11, 2014 11AM)
Anemia
From NHLBI health topic site
(Posted: Jan 01, 2014 0AM)
Hemolytic Anemia
From NHLBI health topic site
(Posted: Jan 01, 2014 0AM)
Immune Thrombocytopenia
From NHLBI health topic site
(Posted: Jan 01, 2014 0AM)
Narcolepsy
From NHLBI health topic site
(Posted: Jan 01, 2014 0AM)
Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: A nationwide population study.
Kuo Chang-Fu et al. 2015 May 4.
(Posted: Jan 01, 2014 0AM)
Autoimmune hemolytic anemia
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune hepatitis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune pulmonary alveolar proteinosis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune polyglandular syndrome type 2
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune polyglandular syndrome type 1
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune Inner Ear disease
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune lymphoproliferative syndrome
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune enteropathy
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Sjogren's syndrome, juvenile, secondary to autoimmune disease
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune progesterone dermatitis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune oophoritis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune myocarditis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Dianzani autoimmune lymphoproliferative syndrome
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Insulin autoimmune syndrome
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune pancreatitis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune polyglandular syndrome type 3
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune autonomic ganglionopathy
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune encephalitis
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune retinopathy
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune gastrointestinal dysmotility
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Necrotizing autoimmune myopathy
From NCATS Genetic and Rare Diseases Information Center
(Posted: Jan 01, 2011 0AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Mar 27, 2024
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