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Phenopedia


Neoplastic Syndromes, Hereditary

357 genes has been reported with Neoplastic Syndromes, Hereditary
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Associated Gene
Total Publication
Meta-analysis Publication
    MLH1 Genopedia 153 1
    MSH2 Genopedia 142 1
    MSH6 Genopedia 92 1
    APC Genopedia 69 2
    MUTYH Genopedia 61 2
    TP53 Genopedia 54 2
    RET Genopedia 50 2
    BRAF Genopedia 40 0
    PMS2 Genopedia 37 0
    NF1 Genopedia 32 2
    BRCA1 Genopedia 25 1
    BRCA2 Genopedia 25 1
    MEN1 Genopedia 23 0
    PTEN Genopedia 22 1
    KRAS Genopedia 20 1
    STK11 Genopedia 15 1
    CTNNB1 Genopedia 14 2
    WT1 Genopedia 13 1
    SMAD4 Genopedia 10 0
    CDKN1B Genopedia 10 0
    CDKN2A Genopedia 10 1
    EXT1 Genopedia 10 0
    MDM2 Genopedia 9 0
    NF2 Genopedia 9 0
    EXT2 Genopedia 9 0
    CHEK2 Genopedia 9 0
    POLD1 Genopedia 9 0
    PIK3CA Genopedia 9 0
    MYH1 Genopedia 9 1
    BMPR1A Genopedia 8 0
    PALB2 Genopedia 7 0
    OGG1 Genopedia 6 0
    MTHFR Genopedia 6 0
    EPCAM Genopedia 6 0
    GSTM1 Genopedia 5 0
    GSTT1 Genopedia 5 0
    FAM123B Genopedia 5 1
    SDHB Genopedia 5 0
    VHL Genopedia 5 0
    AIP Genopedia 5 0
    SDHD Genopedia 4 0
    PTPN11 Genopedia 4 0
    CCND1 Genopedia 4 1
    NTHL1 Genopedia 4 1
    NUDT1 Genopedia 4 0
    PTCH1 Genopedia 4 0
    CDH1 Genopedia 4 0
    NRAS Genopedia 4 1
    UNC5C Genopedia 4 0
    TERT Genopedia 4 0
    FBXW7 Genopedia 3 0
    COX8A Genopedia 3 1
    POLE Genopedia 3 0
    GSTP1 Genopedia 3 0
    NAT2 Genopedia 3 0
    AKT1 Genopedia 3 0
    SMARCB1 Genopedia 3 0
    AURKA Genopedia 3 0
    SPRED1 Genopedia 3 0
    IGF1 Genopedia 3 0
    SMAD7 Genopedia 3 0
    LZTR1 Genopedia 3 0
    TGFBR2 Genopedia 3 0
    PTGS2 Genopedia 3 0
    CYP1A1 Genopedia 3 0
    HRAS Genopedia 3 1
    ATM Genopedia 3 0
    CDKN2B Genopedia 3 0
    MLL3 Genopedia 3 0
    TCF7L2 Genopedia 2 0
    MAX Genopedia 2 0
    NBN Genopedia 2 0
    SUZ12 Genopedia 2 0
    UIMC1 Genopedia 2 0
    IGF2 Genopedia 2 0
    C11orf92 Genopedia 2 0
    BARD1 Genopedia 2 0
    RUNX1 Genopedia 2 0
    CDKN1A Genopedia 2 0
    FLCN Genopedia 2 0
    RNASE1 Genopedia 2 0
    EXO1 Genopedia 2 0
    MRC1 Genopedia 2 0
    RINT1 Genopedia 2 0
    KLLN Genopedia 2 1
    MYCN Genopedia 2 1
    EPHX1 Genopedia 2 0
    MGMT Genopedia 2 0
    AFAP1 Genopedia 2 0
    SDHC Genopedia 2 0
    EGFR Genopedia 2 0
    TSC2 Genopedia 2 0
    XRCC1 Genopedia 2 1
    NAT1 Genopedia 2 1
    RECQL4 Genopedia 2 0
    RNF213 Genopedia 2 0
    FH Genopedia 2 0
    FMO3 Genopedia 2 0
    CDKN2C Genopedia 2 0
    C11orf93 Genopedia 2 0
    CDKN1C Genopedia 2 0
    ERBB2 Genopedia 2 0
    GALNT12 Genopedia 2 0
    GSTA1 Genopedia 2 0
    MC1R Genopedia 2 0
    CLPTM1L Genopedia 1 0
    BRIP1 Genopedia 1 0
    RHPN2 Genopedia 1 0
    EED Genopedia 1 0
    RAPGEF5 Genopedia 1 0
    RABGAP1L Genopedia 1 0
    UGT2B7 Genopedia 1 0
    UGT2B15 Genopedia 1 0
    VEGFA Genopedia 1 0
    CALCA Genopedia 1 0
    AICDA Genopedia 1 0
    RFC1 Genopedia 1 0
    RHBDF1 Genopedia 1 0
    CSMD1 Genopedia 1 0
    PIK3R1 Genopedia 1 0
    PLA2G4A Genopedia 1 0
    PMS1 Genopedia 1 0
    ARL15 Genopedia 1 0
    SPRY1 Genopedia 1 0
    MIRLET7B Genopedia 1 0
    IFNG Genopedia 1 0
    IL1RN Genopedia 1 0
    IL4 Genopedia 1 0
    IL10 Genopedia 1 0
    RPUSD1 Genopedia 1 0
    DHFR Genopedia 1 0
    ENG Genopedia 1 0
    MCM9 Genopedia 1 0
    KAT2A Genopedia 1 0
    GREM1 Genopedia 1 0
    OR51E1 Genopedia 1 0
    DDX1 Genopedia 1 0
    SPRED2 Genopedia 1 0
    MRVI1 Genopedia 1 0
    SEMA3C Genopedia 1 0
    RPP30 Genopedia 1 1
    GALNT6 Genopedia 1 0
    NEIL2 Genopedia 1 0
    GBP3 Genopedia 1 0
    NINL Genopedia 1 0
    ESR1 Genopedia 1 0
    FAP Genopedia 1 0
    CDK6 Genopedia 1 1
    HSPA1L Genopedia 1 0
    NDUFS7 Genopedia 1 0
    KDR Genopedia 1 0
    SPRED3 Genopedia 1 0
    MCM4 Genopedia 1 0
    WIT1 Genopedia 1 0
    DDX41 Genopedia 1 0
    ATP6V0B Genopedia 1 1
    DGCR8 Genopedia 1 1
    UGT1A3 Genopedia 1 0
    RNF43 Genopedia 1 0
    FANCI Genopedia 1 0
    BDNF Genopedia 1 0
    COX1 Genopedia 1 0
    COX3 Genopedia 1 0
    CDC73 Genopedia 1 0
    NAV3 Genopedia 1 0
    BUB1 Genopedia 1 1
    TGFB1 Genopedia 1 0
    BAP1 Genopedia 1 0
    RASAL1 Genopedia 1 0
    CD8A Genopedia 1 0
    SLIT2 Genopedia 1 0
    CDC27 Genopedia 1 0
    FGFBP1 Genopedia 1 0
    EPHB6 Genopedia 1 0
    CD24 Genopedia 1 0
    UST Genopedia 1 0
    BIRC5 Genopedia 1 0
    EIF6 Genopedia 1 0
    Crtc1 Genopedia 1 0
    LIG4 Genopedia 1 0
    CDKN2D Genopedia 1 0
    SEPT9 Genopedia 1 0
    Braf Genopedia 1 0
    CHEK1 Genopedia 1 0
    COX15 Genopedia 1 0
    WDR16 Genopedia 1 0
    DLG2 Genopedia 1 0
    DYNC1I2 Genopedia 1 0
    TP73 Genopedia 1 0
    ADAMTSL3 Genopedia 1 0
    PTCH Genopedia 1 0
    RAF1 Genopedia 1 0
    GUCY1A2 Genopedia 1 0
    SMAD2 Genopedia 1 0
    SPRY3 Genopedia 1 0
    A2ML1 Genopedia 1 0
    CYP1B1 Genopedia 1 0
    Scrib Genopedia 1 0
    WDHD1 Genopedia 1 0
    CHCHD4 Genopedia 1 0
    FAN1 Genopedia 1 1
    MTOR Genopedia 1 0
    ASPM Genopedia 1 0
    TAS2R39 Genopedia 1 0
    C10orf137 Genopedia 1 0
    CNTN6 Genopedia 1 1
    FAM19A3 Genopedia 1 0
    PNPLA1 Genopedia 1 0
    HABP2 Genopedia 1 0
    GALNT11 Genopedia 1 0
    TNN Genopedia 1 0
    SLC10A2 Genopedia 1 0
    ODC1 Genopedia 1 0
    PRKAR1A Genopedia 1 0
    PRKG1 Genopedia 1 0
    GPR126 Genopedia 1 0
    COX2 Genopedia 1 0
    ITK Genopedia 1 0
    C10orf128 Genopedia 1 0
    DNMT3B Genopedia 1 0
    DSC2 Genopedia 1 0
    EPHA3 Genopedia 1 0
    CDKN2B-AS1 Genopedia 1 0
    MUT Genopedia 1 0
    XRCC2 Genopedia 1 0
    XRCC4 Genopedia 1 0
    AXIN2 Genopedia 1 0
    RNF135 Genopedia 1 0
    BUB3 Genopedia 1 1
    KIAA0415 Genopedia 1 0
    OMG Genopedia 1 0
    CSMD3 Genopedia 1 0
    COMT Genopedia 1 0
    MEFV Genopedia 1 0
    PTPN12 Genopedia 1 1
    RBBP4 Genopedia 1 0
    NFKBIZ Genopedia 1 0
    REEP5 Genopedia 1 0
    ZFHX4 Genopedia 1 0
    MLL2 Genopedia 1 0
    SPRY4 Genopedia 1 0
    ARHGAP18 Genopedia 1 0
    CEP57 Genopedia 1 0
    PIEZO1 Genopedia 1 0
    CYLD Genopedia 1 0
    NKAIN2 Genopedia 1 0
    FANCD2 Genopedia 1 0
    MMRN1 Genopedia 1 0
    ARC Genopedia 1 0
    MLH3 Genopedia 1 0
    LAMA1 Genopedia 1 0
    IGKV2-29 Genopedia 1 0
    ARHGAP35 Genopedia 1 0
    DROSHA Genopedia 1 1
    HFE Genopedia 1 0
    APEX1 Genopedia 1 0
    KIF24 Genopedia 1 0
    IL6 Genopedia 1 0
    INPP5D Genopedia 1 0
    JAK2 Genopedia 1 0
    LIN28B Genopedia 1 0
    LRP6 Genopedia 1 1
    NEIL3 Genopedia 1 0
    UGGT2 Genopedia 1 0
    PRKCA Genopedia 1 0
    UGT2B4 Genopedia 1 0
    PTCH2 Genopedia 1 0
    XCL1 Genopedia 1 0
    SLC6A4 Genopedia 1 0
    BMPR1B Genopedia 1 0
    SMARCA4 Genopedia 1 0
    FANCM Genopedia 1 1
    RAD51C Genopedia 1 0
    RIT1 Genopedia 1 0
    ESR2 Genopedia 1 0
    ETV6 Genopedia 1 0
    SETD2 Genopedia 1 0
    ADCY1 Genopedia 1 0
    CYP17A1 Genopedia 1 0
    RBM46 Genopedia 1 0
    IDH1 Genopedia 1 0
    ITPR1 Genopedia 1 0
    KIT Genopedia 1 0
    ATP6 Genopedia 1 0
    PCNA Genopedia 1 0
    UGT1A6 Genopedia 1 0
    UGT1A4 Genopedia 1 0
    KIAA1797 Genopedia 1 1
    PRKDC Genopedia 1 0
    KDM2B Genopedia 1 0
    TGFBR1 Genopedia 1 0
    RPS20 Genopedia 1 1
    PON1 Genopedia 1 0
    UGT1A1 Genopedia 1 0
    KIF26B Genopedia 1 1
    MAP2K7 Genopedia 1 0
    B2M Genopedia 1 0
    HACE1 Genopedia 1 0
    MTAP Genopedia 1 0
    TRNS1 Genopedia 1 0
    MYC Genopedia 1 0
    IL1B Genopedia 1 0
    GSTK1 Genopedia 1 0
    MIA3 Genopedia 1 0
    RTEL1 Genopedia 1 0
    PCTK2 Genopedia 1 1
    NTRK1 Genopedia 1 0
    ALK Genopedia 1 0
    AMPD1 Genopedia 1 0
    IGKV3-20 Genopedia 1 0
    IGKV2-19 Genopedia 1 0
    IGKV2-18 Genopedia 1 0
    IGKV1-22 Genopedia 1 0
    CD274 Genopedia 1 0
    GUCY1A3 Genopedia 1 0
    CEBPA Genopedia 1 0
    CTCF Genopedia 1 0
    KCNQ1OT1 Genopedia 1 0
    ZSWIM7 Genopedia 1 0
    DPH2 Genopedia 1 1
    EIF4G1 Genopedia 1 0
    EPHB2 Genopedia 1 0
    EWSR1 Genopedia 1 0
    FANCB Genopedia 1 0
    FEN1 Genopedia 1 0
    ANKRD26 Genopedia 1 0
    ODF1 Genopedia 1 0
    SERPINE1 Genopedia 1 0
    SUFU Genopedia 1 0
    MITF Genopedia 1 0
    MSH3 Genopedia 1 0
    TRND Genopedia 1 0
    SPRY2 Genopedia 1 0
    HPSE Genopedia 1 0
    KRT71 Genopedia 1 0
    CMM Genopedia 1 0
    E2F2 Genopedia 1 0
    ZHX2 Genopedia 1 0
    FOXO3 Genopedia 1 0
    GATA2 Genopedia 1 0
    IGKV2-23 Genopedia 1 0
    C2orf53 Genopedia 1 0
    GEN1 Genopedia 1 0
    TERF2 Genopedia 1 0
    TJP1 Genopedia 1 0
    TNF Genopedia 1 0
    TSC1 Genopedia 1 0
    XRCC3 Genopedia 1 0
    NEIL1 Genopedia 1 0
    CCDC98 Genopedia 1 0
    GPRC5A Genopedia 1 0
    RPL21 Genopedia 1 0
    SLC19A1 Genopedia 1 0
    BMPR2 Genopedia 1 0
    UGT1A10 Genopedia 1 0
    SDHAF2 Genopedia 1 0
    TMEM127 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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