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Phenopedia


Neoplastic Syndromes, Hereditary

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364 genes has been reported with Neoplastic Syndromes, Hereditary
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Associated Gene
Total Publication
Meta-analysis Publication
    MLH1 Genopedia 157 1
    MSH2 Genopedia 145 1
    MSH6 Genopedia 95 1
    APC Genopedia 69 2
    MUTYH Genopedia 62 2
    TP53 Genopedia 56 2
    RET Genopedia 50 2
    BRAF Genopedia 40 0
    PMS2 Genopedia 40 0
    NF1 Genopedia 32 2
    BRCA2 Genopedia 26 1
    BRCA1 Genopedia 26 1
    MEN1 Genopedia 23 0
    PTEN Genopedia 22 1
    KRAS Genopedia 20 1
    STK11 Genopedia 15 1
    CTNNB1 Genopedia 14 2
    WT1 Genopedia 13 1
    SMAD4 Genopedia 10 0
    POLD1 Genopedia 10 0
    EXT1 Genopedia 10 0
    CDKN2A Genopedia 10 1
    CDKN1B Genopedia 10 0
    CHEK2 Genopedia 10 0
    EXT2 Genopedia 9 0
    PIK3CA Genopedia 9 0
    NF2 Genopedia 9 0
    MDM2 Genopedia 9 0
    MYH1 Genopedia 9 1
    BMPR1A Genopedia 8 0
    PALB2 Genopedia 7 0
    MTHFR Genopedia 6 0
    EPCAM Genopedia 6 0
    OGG1 Genopedia 6 0
    NTHL1 Genopedia 5 1
    GSTM1 Genopedia 5 0
    GSTT1 Genopedia 5 0
    SDHB Genopedia 5 0
    PTCH1 Genopedia 5 0
    FAM123B Genopedia 5 1
    VHL Genopedia 5 0
    AIP Genopedia 5 0
    CDH1 Genopedia 4 0
    UNC5C Genopedia 4 0
    SDHD Genopedia 4 0
    PTPN11 Genopedia 4 0
    CCND1 Genopedia 4 1
    TERT Genopedia 4 0
    NUDT1 Genopedia 4 0
    NRAS Genopedia 4 1
    POLE Genopedia 3 0
    ATM Genopedia 3 0
    GSTP1 Genopedia 3 0
    SMAD7 Genopedia 3 0
    AURKA Genopedia 3 0
    TGFBR2 Genopedia 3 0
    SMARCB1 Genopedia 3 0
    PTGS2 Genopedia 3 0
    FBXW7 Genopedia 3 0
    MLL3 Genopedia 3 0
    COX8A Genopedia 3 1
    SPRED1 Genopedia 3 0
    AKT1 Genopedia 3 0
    CYP1A1 Genopedia 3 0
    NAT2 Genopedia 3 0
    CDKN2B Genopedia 3 0
    HRAS Genopedia 3 1
    IGF1 Genopedia 3 0
    LZTR1 Genopedia 3 0
    TSC2 Genopedia 2 0
    GALNT12 Genopedia 2 0
    RUNX1 Genopedia 2 0
    RECQL4 Genopedia 2 0
    NAT1 Genopedia 2 1
    EXO1 Genopedia 2 0
    IGF2 Genopedia 2 0
    MCM9 Genopedia 2 0
    FH Genopedia 2 0
    FMO3 Genopedia 2 0
    SUZ12 Genopedia 2 0
    EPHX1 Genopedia 2 0
    ERBB2 Genopedia 2 0
    CDKN1A Genopedia 2 0
    GSTA1 Genopedia 2 0
    CDKN2C Genopedia 2 0
    CDKN1C Genopedia 2 0
    KLLN Genopedia 2 1
    C11orf93 Genopedia 2 0
    EGFR Genopedia 2 0
    FLCN Genopedia 2 0
    BARD1 Genopedia 2 0
    RNF213 Genopedia 2 0
    SDHC Genopedia 2 0
    TCF7L2 Genopedia 2 0
    AFAP1 Genopedia 2 0
    RNASE1 Genopedia 2 0
    RINT1 Genopedia 2 0
    XRCC1 Genopedia 2 1
    MAX Genopedia 2 0
    MC1R Genopedia 2 0
    C11orf92 Genopedia 2 0
    MGMT Genopedia 2 0
    MRC1 Genopedia 2 0
    MYCN Genopedia 2 1
    NBN Genopedia 2 0
    MSH3 Genopedia 2 0
    RNF43 Genopedia 2 0
    KIAA1797 Genopedia 2 1
    UIMC1 Genopedia 2 0
    RTEL1 Genopedia 1 0
    NTRK1 Genopedia 1 0
    ODC1 Genopedia 1 0
    ODF1 Genopedia 1 0
    OMG Genopedia 1 0
    SERPINE1 Genopedia 1 0
    FOXP3 Genopedia 1 0
    PCNA Genopedia 1 0
    PCTK2 Genopedia 1 1
    WIT1 Genopedia 1 0
    DDX41 Genopedia 1 0
    SUFU Genopedia 1 0
    SDHAF2 Genopedia 1 0
    KIF26B Genopedia 1 1
    FANCI Genopedia 1 0
    NEIL3 Genopedia 1 0
    PIK3R1 Genopedia 1 0
    PLA2G4A Genopedia 1 0
    ATP6V0B Genopedia 1 1
    PMS1 Genopedia 1 0
    PON1 Genopedia 1 0
    DGCR8 Genopedia 1 1
    UGT1A10 Genopedia 1 0
    UGT1A6 Genopedia 1 0
    ARL15 Genopedia 1 0
    UGT1A4 Genopedia 1 0
    UGT1A1 Genopedia 1 0
    UGT1A3 Genopedia 1 0
    MTAP Genopedia 1 0
    ATP6 Genopedia 1 0
    COX1 Genopedia 1 0
    COX2 Genopedia 1 0
    COX3 Genopedia 1 0
    TRND Genopedia 1 0
    TRNS1 Genopedia 1 0
    MUT Genopedia 1 0
    MYC Genopedia 1 0
    MITF Genopedia 1 0
    SMAD2 Genopedia 1 0
    MEFV Genopedia 1 0
    LRP6 Genopedia 1 1
    MIRLET7B Genopedia 1 0
    MCM4 Genopedia 1 0
    XRCC2 Genopedia 1 0
    XRCC3 Genopedia 1 0
    XRCC4 Genopedia 1 0
    REEP5 Genopedia 1 0
    CDC73 Genopedia 1 0
    CALCA Genopedia 1 0
    NEIL1 Genopedia 1 0
    TJP1 Genopedia 1 0
    TNF Genopedia 1 0
    TP73 Genopedia 1 0
    TSC1 Genopedia 1 0
    TGFB1 Genopedia 1 0
    TGFBR1 Genopedia 1 0
    RPL21 Genopedia 1 0
    RPS20 Genopedia 1 1
    BDNF Genopedia 1 0
    XCL1 Genopedia 1 0
    SLC19A1 Genopedia 1 0
    BMPR1B Genopedia 1 0
    BMPR2 Genopedia 1 0
    SMARCA4 Genopedia 1 0
    BUB1 Genopedia 1 1
    TERF2 Genopedia 1 0
    GALNT11 Genopedia 1 0
    FANCM Genopedia 1 1
    PTPN12 Genopedia 1 1
    HACE1 Genopedia 1 0
    AICDA Genopedia 1 0
    TMEM127 Genopedia 1 0
    PRKAR1A Genopedia 1 0
    UGGT2 Genopedia 1 0
    PRKCA Genopedia 1 0
    PRKDC Genopedia 1 0
    PRKG1 Genopedia 1 0
    MAP2K7 Genopedia 1 0
    B2M Genopedia 1 0
    ADAMTSL3 Genopedia 1 0
    GPR126 Genopedia 1 0
    PTCH Genopedia 1 0
    RFC1 Genopedia 1 0
    RIT1 Genopedia 1 0
    RAD51C Genopedia 1 0
    RAF1 Genopedia 1 0
    RBBP4 Genopedia 1 0
    TNN Genopedia 1 0
    RHBDF1 Genopedia 1 0
    NFKBIZ Genopedia 1 0
    CSMD1 Genopedia 1 0
    SHH Genopedia 1 0
    SLC6A4 Genopedia 1 0
    SLC10A2 Genopedia 1 0
    ENG Genopedia 1 0
    EPHA3 Genopedia 1 0
    EPHB2 Genopedia 1 0
    EPHB6 Genopedia 1 0
    EIF4G1 Genopedia 1 0
    SPRED2 Genopedia 1 0
    CYP1B1 Genopedia 1 0
    CYP17A1 Genopedia 1 0
    ESR1 Genopedia 1 0
    ESR2 Genopedia 1 0
    ETV6 Genopedia 1 0
    EWSR1 Genopedia 1 0
    FANCD2 Genopedia 1 0
    FANCB Genopedia 1 0
    FAP Genopedia 1 0
    FEN1 Genopedia 1 0
    DDX1 Genopedia 1 0
    RBM46 Genopedia 1 0
    C10orf128 Genopedia 1 0
    DHFR Genopedia 1 0
    DLG2 Genopedia 1 0
    DYNC1I2 Genopedia 1 0
    DNMT3B Genopedia 1 0
    DPH2 Genopedia 1 1
    DSC2 Genopedia 1 0
    E2F2 Genopedia 1 0
    COX15 Genopedia 1 0
    CYLD Genopedia 1 0
    NKAIN2 Genopedia 1 0
    OR51E1 Genopedia 1 0
    A2ML1 Genopedia 1 0
    WDR16 Genopedia 1 0
    CMM Genopedia 1 0
    ZSWIM7 Genopedia 1 0
    COMT Genopedia 1 0
    CHCHD4 Genopedia 1 0
    GALNT6 Genopedia 1 0
    KRT71 Genopedia 1 0
    RPUSD1 Genopedia 1 0
    CSMD3 Genopedia 1 0
    LOC100499467 Genopedia 1 0
    UST Genopedia 1 0
    CDK6 Genopedia 1 1
    SPRY3 Genopedia 1 0
    SPRY1 Genopedia 1 0
    SPRY2 Genopedia 1 0
    CDKN2B-AS1 Genopedia 1 0
    CD24 Genopedia 1 0
    CDKN2D Genopedia 1 0
    MRVI1 Genopedia 1 0
    CEBPA Genopedia 1 0
    SEMA3C Genopedia 1 0
    RPP30 Genopedia 1 1
    Scrib Genopedia 1 0
    CTCF Genopedia 1 0
    ADCY1 Genopedia 1 0
    POLQ Genopedia 1 0
    SEPT9 Genopedia 1 0
    HPSE Genopedia 1 0
    KCNQ1OT1 Genopedia 1 0
    Braf Genopedia 1 0
    CHEK1 Genopedia 1 0
    WDHD1 Genopedia 1 0
    ALK Genopedia 1 0
    MTOR Genopedia 1 0
    NEIL2 Genopedia 1 0
    ANKRD26 Genopedia 1 0
    ZHX2 Genopedia 1 0
    FAN1 Genopedia 1 1
    MMRN1 Genopedia 1 0
    NINL Genopedia 1 0
    FOXO3 Genopedia 1 0
    ARC Genopedia 1 0
    ASPM Genopedia 1 0
    TAS2R39 Genopedia 1 0
    C10orf137 Genopedia 1 0
    GATA2 Genopedia 1 0
    GBP3 Genopedia 1 0
    KAT2A Genopedia 1 0
    GREM1 Genopedia 1 0
    AMPD1 Genopedia 1 0
    MLH3 Genopedia 1 0
    CNTN6 Genopedia 1 1
    LAMA1 Genopedia 1 0
    FAM19A3 Genopedia 1 0
    PNPLA1 Genopedia 1 0
    IGKV3-20 Genopedia 1 0
    IGKV2-29 Genopedia 1 0
    IGKV2-23 Genopedia 1 0
    IGKV2-19 Genopedia 1 0
    IGKV2-18 Genopedia 1 0
    IGKV1-22 Genopedia 1 0
    SETD2 Genopedia 1 0
    ARHGAP35 Genopedia 1 0
    DROSHA Genopedia 1 1
    CD274 Genopedia 1 0
    GEN1 Genopedia 1 0
    IL1B Genopedia 1 0
    IL1RN Genopedia 1 0
    IL4 Genopedia 1 0
    IL6 Genopedia 1 0
    IL10 Genopedia 1 0
    INPP5D Genopedia 1 0
    EIF6 Genopedia 1 0
    ITK Genopedia 1 0
    ITPR1 Genopedia 1 0
    JAK2 Genopedia 1 0
    GSTK1 Genopedia 1 0
    NDUFS7 Genopedia 1 0
    MIA3 Genopedia 1 0
    KDR Genopedia 1 0
    KIT Genopedia 1 0
    Crtc1 Genopedia 1 0
    APEX1 Genopedia 1 0
    HSPA1L Genopedia 1 0
    BIRC5 Genopedia 1 0
    C2orf53 Genopedia 1 0
    IDH1 Genopedia 1 0
    IFNG Genopedia 1 0
    KIF24 Genopedia 1 0
    LIN28B Genopedia 1 0
    LCT Genopedia 1 0
    LIG4 Genopedia 1 0
    SPRED3 Genopedia 1 0
    GUCY1A2 Genopedia 1 0
    GUCY1A3 Genopedia 1 0
    HABP2 Genopedia 1 0
    HFE Genopedia 1 0
    BUB3 Genopedia 1 1
    CD8A Genopedia 1 0
    SLIT2 Genopedia 1 0
    ARHGAP18 Genopedia 1 0
    GPRC5A Genopedia 1 0
    CEP57 Genopedia 1 0
    RAPGEF5 Genopedia 1 0
    PIEZO1 Genopedia 1 0
    KIAA0415 Genopedia 1 0
    RABGAP1L Genopedia 1 0
    CDC27 Genopedia 1 0
    FGFBP1 Genopedia 1 0
    PTCH2 Genopedia 1 0
    EED Genopedia 1 0
    NAV3 Genopedia 1 0
    UGT2B4 Genopedia 1 0
    UGT2B7 Genopedia 1 0
    UGT2B15 Genopedia 1 0
    VEGFA Genopedia 1 0
    ZFHX4 Genopedia 1 0
    TAS1R1 Genopedia 1 0
    MLL2 Genopedia 1 0
    CLPTM1L Genopedia 1 0
    SPRY4 Genopedia 1 0
    AXIN2 Genopedia 1 0
    BAP1 Genopedia 1 0
    BRIP1 Genopedia 1 0
    CCDC98 Genopedia 1 0
    RNF135 Genopedia 1 0
    RASAL1 Genopedia 1 0
    KDM2B Genopedia 1 0
    PPM1D Genopedia 1 0
    RHPN2 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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