|
Neoplastic Syndromes, Hereditary
|
|
|
|
383 genes has been reported with Neoplastic Syndromes, Hereditary
|
[Click  to re-sort the table]
|
|
|
|
Meta-analysis Publication
|
MLH1
|
157
|
1
|
| MSH2
|
146
|
1
|
| MSH6
|
97
|
1
|
| APC
|
69
|
2
|
| MUTYH
|
62
|
2
|
| TP53
|
59
|
2
|
| RET
|
50
|
2
|
| PMS2
|
41
|
0
|
| BRAF
|
40
|
0
|
| NF1
|
34
|
2
|
| BRCA2
|
26
|
1
|
| BRCA1
|
26
|
1
|
| MEN1
|
23
|
0
|
| PTEN
|
22
|
1
|
| KRAS
|
20
|
1
|
| STK11
|
15
|
1
|
| CTNNB1
|
14
|
2
|
| WT1
|
13
|
1
|
| CDKN2A
|
11
|
1
|
| SMAD4
|
10
|
0
|
| CDKN1B
|
10
|
0
|
| EXT1
|
10
|
0
|
| POLD1
|
10
|
0
|
| CHEK2
|
10
|
0
|
| MDM2
|
10
|
0
|
| PIK3CA
|
9
|
0
|
| NF2
|
9
|
0
|
| EXT2
|
9
|
0
|
| MYH1
|
9
|
1
|
| BMPR1A
|
8
|
0
|
| EPCAM
|
8
|
0
|
| PALB2
|
7
|
0
|
| OGG1
|
6
|
0
|
| MTHFR
|
6
|
0
|
| GSTM1
|
5
|
0
|
| SDHB
|
5
|
0
|
| PTCH1
|
5
|
0
|
| GSTT1
|
5
|
0
|
| VHL
|
5
|
0
|
| AIP
|
5
|
0
|
| NTHL1
|
5
|
1
|
| FAM123B
|
5
|
1
|
| UNC5C
|
4
|
0
|
| NUDT1
|
4
|
0
|
| PTPN11
|
4
|
0
|
| SDHD
|
4
|
0
|
| CDH1
|
4
|
0
|
| NRAS
|
4
|
1
|
| ATM
|
4
|
0
|
| TERT
|
4
|
0
|
| CCND1
|
4
|
1
|
| FBXW7
|
3
|
0
|
| COX8A
|
3
|
1
|
| AKT1
|
3
|
0
|
| POLE
|
3
|
0
|
| MLL3
|
3
|
0
|
| SPRED1
|
3
|
0
|
| SMAD7
|
3
|
0
|
| NAT2
|
3
|
0
|
| CYP1A1
|
3
|
0
|
| TGFBR2
|
3
|
0
|
| LZTR1
|
3
|
0
|
| CDKN2B
|
3
|
0
|
| FAP
|
3
|
0
|
| SMARCB1
|
3
|
0
|
| GSTP1
|
3
|
0
|
| AURKA
|
3
|
0
|
| PTGS2
|
3
|
0
|
| HRAS
|
3
|
1
|
| IGF1
|
3
|
0
|
| MRC1
|
2
|
0
|
| CD8A
|
2
|
0
|
| GSTA1
|
2
|
0
|
| GALNT12
|
2
|
0
|
| RINT1
|
2
|
0
|
| FLCN
|
2
|
0
|
| KLLN
|
2
|
1
|
| KIAA1797
|
2
|
1
|
| EGFR
|
2
|
0
|
| MGMT
|
2
|
0
|
| MYCN
|
2
|
1
|
| SDHC
|
2
|
0
|
| TSC2
|
2
|
0
|
| BAP1
|
2
|
0
|
| CDKN2C
|
2
|
0
|
| C11orf93
|
2
|
0
|
| FH
|
2
|
0
|
| MITF
|
2
|
0
|
| MSH3
|
2
|
0
|
| RNF213
|
2
|
0
|
| TCF7L2
|
2
|
0
|
| XRCC1
|
2
|
1
|
| PPM1D
|
2
|
0
|
| BARD1
|
2
|
0
|
| C11orf92
|
2
|
0
|
| RUNX1
|
2
|
0
|
| MCM9
|
2
|
0
|
| IGF2
|
2
|
0
|
| SUZ12
|
2
|
0
|
| ERBB2
|
2
|
0
|
| EXO1
|
2
|
0
|
| RNASE1
|
2
|
0
|
| CDKN1A
|
2
|
0
|
| AFAP1
|
2
|
0
|
| SLTM
|
2
|
0
|
| EPHX1
|
2
|
0
|
| NBN
|
2
|
0
|
| MAX
|
2
|
0
|
| RNF43
|
2
|
0
|
| FMO3
|
2
|
0
|
| NAT1
|
2
|
1
|
| RECQL4
|
2
|
0
|
| CDKN1C
|
2
|
0
|
| UIMC1
|
2
|
0
|
| MC1R
|
2
|
0
|
| RPS20
|
1
|
1
|
| CSMD1
|
1
|
0
|
| MAP2K7
|
1
|
0
|
| PIK3R1
|
1
|
0
|
| UGT1A1
|
1
|
0
|
| UGT2B7
|
1
|
0
|
| CALCA
|
1
|
0
|
| CLPTM1L
|
1
|
0
|
| RHPN2
|
1
|
0
|
| RAPGEF5
|
1
|
0
|
| RTEL1
|
1
|
0
|
| CTCF
|
1
|
0
|
| ABCC1
|
1
|
0
|
| TRNS1
|
1
|
0
|
| PCTK2
|
1
|
1
|
| EPHB2
|
1
|
0
|
| ETV4
|
1
|
0
|
| FANCB
|
1
|
0
|
| FEN1
|
1
|
0
|
| ANKRD26
|
1
|
0
|
| KAT2A
|
1
|
0
|
| IGKV2-18
|
1
|
0
|
| CD274
|
1
|
0
|
| GUCY1A3
|
1
|
0
|
| IL1RN
|
1
|
0
|
| IL10
|
1
|
0
|
| GSTK1
|
1
|
0
|
| MIA3
|
1
|
0
|
| SLC19A1
|
1
|
0
|
| SMO
|
1
|
0
|
| TERF2
|
1
|
0
|
| TSC1
|
1
|
0
|
| GBP3
|
1
|
0
|
| C2orf53
|
1
|
0
|
| SEMA3C
|
1
|
0
|
| HPSE
|
1
|
0
|
| ESR1
|
1
|
0
|
| ZHX2
|
1
|
0
|
| KDM4C
|
1
|
0
|
| SDHAF2
|
1
|
0
|
| FANCI
|
1
|
0
|
| TMEM127
|
1
|
0
|
| COX3
|
1
|
0
|
| FANCD2
|
1
|
0
|
| ARHGAP35
|
1
|
0
|
| CD24
|
1
|
0
|
| POLQ
|
1
|
0
|
| DLG2
|
1
|
0
|
| DYNC1I2
|
1
|
0
|
| EPHB6
|
1
|
0
|
| PTPN12
|
1
|
1
|
| RB1
|
1
|
0
|
| RBBP4
|
1
|
0
|
| APEX1
|
1
|
0
|
| IL6
|
1
|
0
|
| INPP5D
|
1
|
0
|
| EIF6
|
1
|
0
|
| MLL2
|
1
|
0
|
| SPRY4
|
1
|
0
|
| RASAL1
|
1
|
0
|
| ARHGAP18
|
1
|
0
|
| CEP57
|
1
|
0
|
| CDC27
|
1
|
0
|
| REEP5
|
1
|
0
|
| WDHD1
|
1
|
0
|
| CHCHD4
|
1
|
0
|
| A2ML1
|
1
|
0
|
| ODC1
|
1
|
0
|
| PIWIL2
|
1
|
0
|
| PRKG1
|
1
|
0
|
| GPR126
|
1
|
0
|
| RBM46
|
1
|
0
|
| DNMT3B
|
1
|
0
|
| EPHA3
|
1
|
0
|
| ASPM
|
1
|
0
|
| TAS2R39
|
1
|
0
|
| C10orf137
|
1
|
0
|
| CNTN6
|
1
|
1
|
| SETD2
|
1
|
0
|
| ITK
|
1
|
0
|
| LCT
|
1
|
0
|
| XCL1
|
1
|
0
|
| BMPR1B
|
1
|
0
|
| SMARCA4
|
1
|
0
|
| USP7
|
1
|
0
|
| TAS1R1
|
1
|
0
|
| TXNRD1
|
1
|
0
|
| BUB3
|
1
|
1
|
| KIAA0430
|
1
|
0
|
| EWSR1
|
1
|
0
|
| ALK
|
1
|
0
|
| SPRY1
|
1
|
0
|
| CEBPA
|
1
|
0
|
| KCNQ1OT1
|
1
|
0
|
| RPUSD1
|
1
|
0
|
| DHFR
|
1
|
0
|
| EIF4G1
|
1
|
0
|
| IL1B
|
1
|
0
|
| GREM1
|
1
|
0
|
| IFNG
|
1
|
0
|
| FOXP3
|
1
|
0
|
| PLA2G4A
|
1
|
0
|
| PON1
|
1
|
0
|
| ARL15
|
1
|
0
|
| B2M
|
1
|
0
|
| HACE1
|
1
|
0
|
| UGT2B15
|
1
|
0
|
| BRIP1
|
1
|
0
|
| RFC1
|
1
|
0
|
| NAV3
|
1
|
0
|
| GPRC5A
|
1
|
0
|
| XRCC3
|
1
|
0
|
| NEIL1
|
1
|
0
|
| BUB1
|
1
|
1
|
| TJP1
|
1
|
0
|
| RENBP
|
1
|
0
|
| DGCR8
|
1
|
1
|
| WIT1
|
1
|
0
|
| DDX41
|
1
|
0
|
| FOXO3
|
1
|
0
|
| NEIL2
|
1
|
0
|
| GATA2
|
1
|
0
|
| HSPA1L
|
1
|
0
|
| SPRED3
|
1
|
0
|
| CMM
|
1
|
0
|
| OR51E1
|
1
|
0
|
| DDX1
|
1
|
0
|
| E2F2
|
1
|
0
|
| SPRED2
|
1
|
0
|
| MRVI1
|
1
|
0
|
| KRT71
|
1
|
0
|
| CDK4
|
1
|
0
|
| CD4
|
1
|
0
|
| FGFBP1
|
1
|
0
|
| ZFHX4
|
1
|
0
|
| SMAD2
|
1
|
0
|
| RAF1
|
1
|
0
|
| UGGT2
|
1
|
0
|
| PTCH
|
1
|
0
|
| MLH3
|
1
|
0
|
| LAMA1
|
1
|
0
|
| DROSHA
|
1
|
1
|
| HFE
|
1
|
0
|
| BIRC5
|
1
|
0
|
| KIF24
|
1
|
0
|
| LIG4
|
1
|
0
|
| UST
|
1
|
0
|
| CDKN2D
|
1
|
0
|
| SEPT9
|
1
|
0
|
| Braf
|
1
|
0
|
| CSMD3
|
1
|
0
|
| COMT
|
1
|
0
|
| COX15
|
1
|
0
|
| WDR16
|
1
|
0
|
| CYLD
|
1
|
0
|
| NKAIN2
|
1
|
0
|
| PRKAR1A
|
1
|
0
|
| FANCM
|
1
|
1
|
| SPRY3
|
1
|
0
|
| Scrib
|
1
|
0
|
| PCNA
|
1
|
0
|
| UGT1A6
|
1
|
0
|
| ETV6
|
1
|
0
|
| FAM19A3
|
1
|
0
|
| HABP2
|
1
|
0
|
| ATP6
|
1
|
0
|
| MUT
|
1
|
0
|
| CYP1B1
|
1
|
0
|
| CYP17A1
|
1
|
0
|
| C10orf128
|
1
|
0
|
| SLC6A4
|
1
|
0
|
| SLC10A2
|
1
|
0
|
| UGT2B4
|
1
|
0
|
| AXIN2
|
1
|
0
|
| RNF135
|
1
|
0
|
| PTCH2
|
1
|
0
|
| KIAA0415
|
1
|
0
|
| KDM2B
|
1
|
0
|
| EED
|
1
|
0
|
| RABGAP1L
|
1
|
0
|
| TGFBR1
|
1
|
0
|
| VEGFA
|
1
|
0
|
| RHBDF1
|
1
|
0
|
| IL4
|
1
|
0
|
| ZSWIM7
|
1
|
0
|
| DPH2
|
1
|
1
|
| ENG
|
1
|
0
|
| AMPD1
|
1
|
0
|
| IGKV3-20
|
1
|
0
|
| IGKV2-19
|
1
|
0
|
| IGKV1-22
|
1
|
0
|
| NTRK1
|
1
|
0
|
| PMS1
|
1
|
0
|
| KIF26B
|
1
|
1
|
| AICDA
|
1
|
0
|
| MIRLET7B
|
1
|
0
|
| MTAP
|
1
|
0
|
| MYC
|
1
|
0
|
| GEN1
|
1
|
0
|
| NDUFS7
|
1
|
0
|
| KDR
|
1
|
0
|
| MCM4
|
1
|
0
|
| MDM4
|
1
|
0
|
| CDK6
|
1
|
1
|
| SPRY2
|
1
|
0
|
| RPP30
|
1
|
1
|
| GALNT6
|
1
|
0
|
| ODF1
|
1
|
0
|
| SERPINE1
|
1
|
0
|
| SUFU
|
1
|
0
|
| ATP6V0B
|
1
|
1
|
| UGT1A10
|
1
|
0
|
| UGT1A3
|
1
|
0
|
| NDE1
|
1
|
0
|
| RPL21
|
1
|
0
|
| BDNF
|
1
|
0
|
| BMPR2
|
1
|
0
|
| TGFB1
|
1
|
0
|
| TNF
|
1
|
0
|
| CDC73
|
1
|
0
|
| NINL
|
1
|
0
|
| IGKV2-23
|
1
|
0
|
| COX1
|
1
|
0
|
| TRND
|
1
|
0
|
| CCDC98
|
1
|
0
|
| SLIT2
|
1
|
0
|
| ULK2
|
1
|
0
|
| PIEZO1
|
1
|
0
|
| MEFV
|
1
|
0
|
| OMG
|
1
|
0
|
| NEIL3
|
1
|
0
|
| PRKCA
|
1
|
0
|
| ADAMTSL3
|
1
|
0
|
| NFKBIZ
|
1
|
0
|
| TP73
|
1
|
0
|
| CHEK1
|
1
|
0
|
| EREG
|
1
|
0
|
| Trp53
|
1
|
0
|
| MMRN1
|
1
|
0
|
| ARC
|
1
|
0
|
| IGKV2-29
|
1
|
0
|
| GUCY1A2
|
1
|
0
|
| JAK2
|
1
|
0
|
| Crtc1
|
1
|
0
|
| LIN28B
|
1
|
0
|
| LRP6
|
1
|
1
|
| ITPR1
|
1
|
0
|
| KIT
|
1
|
0
|
| COX2
|
1
|
0
|
| MYH11
|
1
|
0
|
| UGT1A4
|
1
|
0
|
| PRKDC
|
1
|
0
|
| IDH1
|
1
|
0
|
| DSC2
|
1
|
0
|
| ESR2
|
1
|
0
|
| FAN1
|
1
|
1
|
| MTOR
|
1
|
0
|
| PNPLA1
|
1
|
0
|
| ADCY1
|
1
|
0
|
| CDKN2B-AS1
|
1
|
0
|
| LOC100499467
|
1
|
0
|
| RAD51C
|
1
|
0
|
| RIT1
|
1
|
0
|
| GALNT11
|
1
|
0
|
| TNN
|
1
|
0
|
| SHH
|
1
|
0
|
| XRCC2
|
1
|
0
|
| XRCC4
|
1
|
0
|
|
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number
in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder
reflects all text searches of the disease term including the indexed term.
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