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Neoplasms, Second Primary
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284 genes has been reported with Neoplasms, Second Primary
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[Click  to re-sort the table]
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Meta-analysis Publication
|
BRCA2
|
22
|
1
|
| BRCA1
|
21
|
1
|
| TP53
|
14
|
0
|
| KRAS
|
10
|
0
|
| MLH1
|
7
|
0
|
| MSH2
|
6
|
0
|
| MSH6
|
6
|
0
|
| CDKN2A
|
6
|
0
|
| NQO1
|
5
|
0
|
| FLT3
|
5
|
0
|
| GSTM1
|
5
|
0
|
| GSTP1
|
5
|
0
|
| GSTT1
|
5
|
0
|
| NPM1
|
5
|
0
|
| XRCC1
|
5
|
0
|
| XRCC3
|
5
|
0
|
| VDR
|
4
|
0
|
| ATM
|
4
|
0
|
| NRAS
|
4
|
0
|
| EGFR
|
4
|
0
|
| CHEK2
|
4
|
1
|
| COX8A
|
3
|
0
|
| CYP3A4
|
3
|
0
|
| ALDH2
|
3
|
0
|
| ERCC2
|
3
|
0
|
| MTHFR
|
3
|
0
|
| FAS
|
3
|
0
|
| IDH1
|
3
|
0
|
| IDH2
|
3
|
0
|
| PMS2
|
3
|
0
|
| VEGFA
|
3
|
0
|
| TP73
|
3
|
0
|
| TNF
|
3
|
0
|
| KIT
|
2
|
0
|
| TPMT
|
2
|
0
|
| BAP1
|
2
|
0
|
| RB1
|
2
|
0
|
| NBN
|
2
|
0
|
| SUFU
|
2
|
0
|
| PIK3CA
|
2
|
0
|
| RXRA
|
2
|
0
|
| BRAF
|
2
|
0
|
| RAD51
|
2
|
0
|
| SMO
|
2
|
0
|
| GSTM3
|
2
|
0
|
| IGF1R
|
2
|
0
|
| GHRHR
|
2
|
0
|
| JAK2
|
2
|
0
|
| MLL
|
2
|
0
|
| FASLG
|
2
|
0
|
| MDM2
|
2
|
0
|
| MDM4
|
2
|
0
|
| GC
|
2
|
0
|
| DNMT3A
|
2
|
0
|
| DNMT3B
|
2
|
0
|
| CYP2D6
|
2
|
0
|
| CDKN1A
|
2
|
0
|
| ADH1B
|
2
|
0
|
| CDK4
|
2
|
0
|
| CDK6
|
1
|
0
|
| FCGR1C
|
1
|
0
|
| BCL2L10
|
1
|
0
|
| BCL2L11
|
1
|
0
|
| DDX20
|
1
|
0
|
| ATG4A
|
1
|
0
|
| CYP2R1
|
1
|
0
|
| CDKN2C
|
1
|
0
|
| COX4NB
|
1
|
0
|
| PGRMC2
|
1
|
0
|
| CEBPA
|
1
|
0
|
| ATP5L
|
1
|
0
|
| RGS14
|
1
|
0
|
| IGF2BP1
|
1
|
0
|
| CFTR
|
1
|
0
|
| ADH5
|
1
|
0
|
| ADH6
|
1
|
0
|
| CDKN1B
|
1
|
0
|
| E2F7
|
1
|
0
|
| CTNNB1
|
1
|
0
|
| CYP1A1
|
1
|
0
|
| CYP3A5
|
1
|
0
|
| CYP24A1
|
1
|
0
|
| CYP27A1
|
1
|
0
|
| CYP27B1
|
1
|
0
|
| DDB2
|
1
|
0
|
| UGT3A2
|
1
|
0
|
| ASXL1
|
1
|
0
|
| CYP2E1
|
1
|
0
|
| DKC1
|
1
|
0
|
| E2F2
|
1
|
0
|
| AHR
|
1
|
0
|
| EPHX2
|
1
|
0
|
| FANCD2
|
1
|
0
|
| FEN1
|
1
|
0
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| FGF2
|
1
|
0
|
| FGF5
|
1
|
0
|
| FGF9
|
1
|
0
|
| FGFR3
|
1
|
0
|
| ZHX2
|
1
|
0
|
| FOXO1
|
1
|
0
|
| EIF2C1
|
1
|
0
|
| RPS6KC1
|
1
|
0
|
| GH1
|
1
|
0
|
| GHR
|
1
|
0
|
| ERCC5
|
1
|
0
|
| ERN1
|
1
|
0
|
| EZH1
|
1
|
0
|
| EZH2
|
1
|
0
|
| DICER1
|
1
|
0
|
| SIRT3
|
1
|
0
|
| NEIL2
|
1
|
0
|
| RICTOR
|
1
|
0
|
| TXN2
|
1
|
0
|
| SULT4A1
|
1
|
0
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| RGS22
|
1
|
0
|
| HSPB8
|
1
|
0
|
| MEN1
|
1
|
0
|
| MGMT
|
1
|
0
|
| MKI67
|
1
|
0
|
| INS
|
1
|
0
|
| INSR
|
1
|
0
|
| IRS1
|
1
|
0
|
| ARNTL
|
1
|
0
|
| SMAD1
|
1
|
0
|
| SMAD3
|
1
|
0
|
| SMAD4
|
1
|
0
|
| SMAD7
|
1
|
0
|
| MBD1
|
1
|
0
|
| MC1R
|
1
|
0
|
| MLLT3
|
1
|
0
|
| MNAT1
|
1
|
0
|
| NDUFS7
|
1
|
0
|
| MTR
|
1
|
0
|
| OGG1
|
1
|
0
|
| ATP5A1
|
1
|
0
|
| RRM2B
|
1
|
0
|
| GEMIN4
|
1
|
0
|
| IGF2AS
|
1
|
0
|
| ANGPT4
|
1
|
0
|
| PDGFB
|
1
|
0
|
| PDGFRA
|
1
|
0
|
| GHITM
|
1
|
0
|
| SMC1B
|
1
|
0
|
| TNFRSF21
|
1
|
0
|
| GLI1
|
1
|
0
|
| GLI2
|
1
|
0
|
| IL28B
|
1
|
0
|
| IGHVIII-38-1
|
1
|
0
|
| FLJ35220
|
1
|
0
|
| GPER
|
1
|
0
|
| COX18
|
1
|
0
|
| GPX1
|
1
|
0
|
| GPX7
|
1
|
0
|
| RNASEN
|
1
|
0
|
| GSTA1
|
1
|
0
|
| HLA-A
|
1
|
0
|
| HLA-B
|
1
|
0
|
| HLX
|
1
|
0
|
| APC
|
1
|
0
|
| XIAP
|
1
|
0
|
| BIRC5
|
1
|
0
|
| ICAM1
|
1
|
0
|
| IDE
|
1
|
0
|
| IGF2
|
1
|
0
|
| IGFBP1
|
1
|
0
|
| IGFBP2
|
1
|
0
|
| IGFBP3
|
1
|
0
|
| IGFBP5
|
1
|
0
|
| IHH
|
1
|
0
|
| IKBKB
|
1
|
0
|
| IL1R1
|
1
|
0
|
| GSTM4
|
1
|
0
|
| GSTM5
|
1
|
0
|
| IFN1@
|
1
|
0
|
| IGF1
|
1
|
0
|
| SNAI1
|
1
|
0
|
| BNIP3L
|
1
|
0
|
| SOS1
|
1
|
0
|
| SP1
|
1
|
0
|
| SPP1
|
1
|
0
|
| RAD51L3
|
1
|
0
|
| RAN
|
1
|
0
|
| SST
|
1
|
0
|
| SSTR1
|
1
|
0
|
| SSTR2
|
1
|
0
|
| AURKA
|
1
|
0
|
| SULT1C2
|
1
|
0
|
| TAGLN
|
1
|
0
|
| TLR2
|
1
|
0
|
| TLR4
|
1
|
0
|
| SERPINB3
|
1
|
0
|
| RGS18
|
1
|
0
|
| SHH
|
1
|
0
|
| PIK3R1
|
1
|
0
|
| PLK1
|
1
|
0
|
| PMS2L3
|
1
|
0
|
| ATP6V1C1
|
1
|
0
|
| NDUFA6
|
1
|
0
|
| NFKB1
|
1
|
0
|
| NFKBIB
|
1
|
0
|
| NODAL
|
1
|
0
|
| NOTCH1
|
1
|
0
|
| RET
|
1
|
0
|
| BCL2L2
|
1
|
0
|
| RGS1
|
1
|
0
|
| RGS2
|
1
|
0
|
| RGS3
|
1
|
0
|
| RGS4
|
1
|
0
|
| RGS7
|
1
|
0
|
| RGS10
|
1
|
0
|
| RGS12
|
1
|
0
|
| RGS13
|
1
|
0
|
| RGS16
|
1
|
0
|
| RING1
|
1
|
0
|
| RNF2
|
1
|
0
|
| RPA1
|
1
|
0
|
| RPS6KA3
|
1
|
0
|
| RPS6KB1
|
1
|
0
|
| RPS6KB2
|
1
|
0
|
| RRM1
|
1
|
0
|
| POLH
|
1
|
0
|
| PON1
|
1
|
0
|
| DGCR8
|
1
|
0
|
| TET2
|
1
|
0
|
| CHFR
|
1
|
0
|
| PDGFC
|
1
|
0
|
| PROX1
|
1
|
0
|
| PSMD9
|
1
|
0
|
| PTEN
|
1
|
0
|
| BAG1
|
1
|
0
|
| BIRC6
|
1
|
0
|
| XPO5
|
1
|
0
|
| PTPN11
|
1
|
0
|
| BAX
|
1
|
0
|
| PVT1
|
1
|
0
|
| ALDH18A1
|
1
|
0
|
| CDC7
|
1
|
0
|
| FZD4
|
1
|
0
|
| CASP2
|
1
|
0
|
| CASP7
|
1
|
0
|
| CASP8
|
1
|
0
|
| CASR
|
1
|
0
|
| CAT
|
1
|
0
|
| RGS5
|
1
|
0
|
| RGS8
|
1
|
0
|
| CAV1
|
1
|
0
|
| CAV2
|
1
|
0
|
| RGS20
|
1
|
0
|
| RUNX1
|
1
|
0
|
| PTCH2
|
1
|
0
|
| IRS2
|
1
|
0
|
| CBL
|
1
|
0
|
| TNFSF10
|
1
|
0
|
| RGS11
|
1
|
0
|
| RGS9
|
1
|
0
|
| TNFRSF10D
|
1
|
0
|
| TNFRSF10B
|
1
|
0
|
| PROM1
|
1
|
0
|
| NR1I2
|
1
|
0
|
| NAT1
|
1
|
0
|
| BMF
|
1
|
0
|
| ANGPTL1
|
1
|
0
|
| ACVR1B
|
1
|
0
|
| CD4
|
1
|
0
|
| CD34
|
1
|
0
|
| BAG5
|
1
|
0
|
| BAG3
|
1
|
0
|
| CD44
|
1
|
0
|
| SETD1A
|
1
|
0
|
| MRC2
|
1
|
0
|
| CDC25C
|
1
|
0
|
| TSC1
|
1
|
0
|
| U2AF1
|
1
|
0
|
| WNT11
|
1
|
0
|
| WNT2B
|
1
|
0
|
| WT1
|
1
|
0
|
| XRCC5
|
1
|
0
|
| CA9
|
1
|
0
|
| ATG9A
|
1
|
0
|
| FZD3
|
1
|
0
|
| UGT2A3
|
1
|
0
|
| NHEJ1
|
1
|
0
|
| COL18A1
|
1
|
0
|
| AXIN2
|
1
|
0
|
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Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number
in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder
reflects all text searches of the disease term including the indexed term.
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