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Phenopedia


Neoplasms, Second Primary
280 genes has been reported with Neoplasms, Second Primary
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Associated Gene
Total Publication
Meta-analysis Publication
    BRCA2 Genopedia 22 1
    BRCA1 Genopedia 21 1
    TP53 Genopedia 13 0
    KRAS Genopedia 8 0
    MLH1 Genopedia 7 0
    MSH6 Genopedia 6 0
    MSH2 Genopedia 6 0
    GSTP1 Genopedia 5 0
    CDKN2A Genopedia 5 0
    XRCC1 Genopedia 5 0
    XRCC3 Genopedia 5 0
    GSTT1 Genopedia 5 0
    NQO1 Genopedia 5 0
    FLT3 Genopedia 5 0
    GSTM1 Genopedia 5 0
    CHEK2 Genopedia 4 1
    VDR Genopedia 4 0
    NPM1 Genopedia 4 0
    NRAS Genopedia 4 0
    ATM Genopedia 4 0
    PMS2 Genopedia 3 0
    CYP3A4 Genopedia 3 0
    EGFR Genopedia 3 0
    TP73 Genopedia 3 0
    IDH1 Genopedia 3 0
    ERCC2 Genopedia 3 0
    ALDH2 Genopedia 3 0
    TNF Genopedia 3 0
    IDH2 Genopedia 3 0
    FAS Genopedia 3 0
    VEGFA Genopedia 3 0
    COX8A Genopedia 3 0
    MTHFR Genopedia 3 0
    GC Genopedia 2 0
    CDKN1A Genopedia 2 0
    DNMT3B Genopedia 2 0
    GHRHR Genopedia 2 0
    RAD51 Genopedia 2 0
    FASLG Genopedia 2 0
    RB1 Genopedia 2 0
    BRAF Genopedia 2 0
    TPMT Genopedia 2 0
    PIK3CA Genopedia 2 0
    MDM2 Genopedia 2 0
    SMO Genopedia 2 0
    NBN Genopedia 2 0
    CYP2D6 Genopedia 2 0
    RXRA Genopedia 2 0
    SUFU Genopedia 2 0
    MDM4 Genopedia 2 0
    IGF1R Genopedia 2 0
    GSTM3 Genopedia 2 0
    KIT Genopedia 2 0
    JAK2 Genopedia 2 0
    ADH1B Genopedia 2 0
    BAP1 Genopedia 2 0
    CDK4 Genopedia 2 0
    CDKN2C Genopedia 1 0
    PGRMC2 Genopedia 1 0
    E2F2 Genopedia 1 0
    EZH2 Genopedia 1 0
    NEIL2 Genopedia 1 0
    TXN2 Genopedia 1 0
    EIF2C1 Genopedia 1 0
    FLJ35220 Genopedia 1 0
    NFKBIB Genopedia 1 0
    NODAL Genopedia 1 0
    DGCR8 Genopedia 1 0
    PVT1 Genopedia 1 0
    RGS1 Genopedia 1 0
    RGS7 Genopedia 1 0
    RRM1 Genopedia 1 0
    TLR2 Genopedia 1 0
    WNT11 Genopedia 1 0
    CAT Genopedia 1 0
    RGS20 Genopedia 1 0
    RGS9 Genopedia 1 0
    OGG1 Genopedia 1 0
    ANGPT4 Genopedia 1 0
    PON1 Genopedia 1 0
    RING1 Genopedia 1 0
    DDX20 Genopedia 1 0
    CYP2R1 Genopedia 1 0
    FGF5 Genopedia 1 0
    IGF2 Genopedia 1 0
    IGFBP5 Genopedia 1 0
    MEN1 Genopedia 1 0
    SSTR1 Genopedia 1 0
    RUNX1 Genopedia 1 0
    PROM1 Genopedia 1 0
    CD4 Genopedia 1 0
    DKC1 Genopedia 1 0
    SULT4A1 Genopedia 1 0
    TNFRSF21 Genopedia 1 0
    GPER Genopedia 1 0
    UGT3A2 Genopedia 1 0
    RGS14 Genopedia 1 0
    ADH6 Genopedia 1 0
    BIRC6 Genopedia 1 0
    XPO5 Genopedia 1 0
    ALDH18A1 Genopedia 1 0
    SULT1C2 Genopedia 1 0
    FZD3 Genopedia 1 0
    BIRC5 Genopedia 1 0
    IGFBP3 Genopedia 1 0
    IKBKB Genopedia 1 0
    INSR Genopedia 1 0
    MGMT Genopedia 1 0
    NDUFA6 Genopedia 1 0
    PMS2L3 Genopedia 1 0
    PROX1 Genopedia 1 0
    PSMD9 Genopedia 1 0
    PTEN Genopedia 1 0
    RAD51L3 Genopedia 1 0
    RGS2 Genopedia 1 0
    RGS13 Genopedia 1 0
    RPS6KA3 Genopedia 1 0
    CA9 Genopedia 1 0
    AXIN2 Genopedia 1 0
    CASP7 Genopedia 1 0
    PTCH2 Genopedia 1 0
    BAG5 Genopedia 1 0
    SETD1A Genopedia 1 0
    CYP1A1 Genopedia 1 0
    CYP3A5 Genopedia 1 0
    GLI2 Genopedia 1 0
    GPX7 Genopedia 1 0
    IDE Genopedia 1 0
    IGFBP1 Genopedia 1 0
    SMAD3 Genopedia 1 0
    MNAT1 Genopedia 1 0
    ERN1 Genopedia 1 0
    FOXO1 Genopedia 1 0
    DICER1 Genopedia 1 0
    GLI1 Genopedia 1 0
    HLX Genopedia 1 0
    ICAM1 Genopedia 1 0
    IL1R1 Genopedia 1 0
    RRM2B Genopedia 1 0
    PDGFB Genopedia 1 0
    PDGFC Genopedia 1 0
    RGS16 Genopedia 1 0
    RNF2 Genopedia 1 0
    SP1 Genopedia 1 0
    SSTR2 Genopedia 1 0
    MKI67 Genopedia 1 0
    ATG4A Genopedia 1 0
    WNT2B Genopedia 1 0
    XRCC5 Genopedia 1 0
    MRC2 Genopedia 1 0
    ATP6V1C1 Genopedia 1 0
    TET2 Genopedia 1 0
    RGS10 Genopedia 1 0
    RGS12 Genopedia 1 0
    RPS6KB1 Genopedia 1 0
    RPS6KB2 Genopedia 1 0
    SERPINB3 Genopedia 1 0
    SHH Genopedia 1 0
    SNAI1 Genopedia 1 0
    SOS1 Genopedia 1 0
    AURKA Genopedia 1 0
    COL18A1 Genopedia 1 0
    CDC7 Genopedia 1 0
    RGS8 Genopedia 1 0
    CAV1 Genopedia 1 0
    CBL Genopedia 1 0
    CD34 Genopedia 1 0
    IGF1 Genopedia 1 0
    IHH Genopedia 1 0
    CDKN1B Genopedia 1 0
    COX4NB Genopedia 1 0
    CFTR Genopedia 1 0
    E2F7 Genopedia 1 0
    CYP2E1 Genopedia 1 0
    ERCC5 Genopedia 1 0
    FGFR3 Genopedia 1 0
    RGS22 Genopedia 1 0
    SMC1B Genopedia 1 0
    NDUFS7 Genopedia 1 0
    CDK6 Genopedia 1 0
    CYP27B1 Genopedia 1 0
    HSPB8 Genopedia 1 0
    RPS6KC1 Genopedia 1 0
    RGS4 Genopedia 1 0
    U2AF1 Genopedia 1 0
    IRS2 Genopedia 1 0
    ADH5 Genopedia 1 0
    SST Genopedia 1 0
    TLR4 Genopedia 1 0
    ARNTL Genopedia 1 0
    NFKB1 Genopedia 1 0
    CHFR Genopedia 1 0
    PTPN11 Genopedia 1 0
    BCL2L2 Genopedia 1 0
    DDB2 Genopedia 1 0
    AHR Genopedia 1 0
    EPHX2 Genopedia 1 0
    FGF9 Genopedia 1 0
    GSTA1 Genopedia 1 0
    HLA-B Genopedia 1 0
    ATG9A Genopedia 1 0
    FZD4 Genopedia 1 0
    BAG3 Genopedia 1 0
    BAX Genopedia 1 0
    RET Genopedia 1 0
    RPA1 Genopedia 1 0
    RGS18 Genopedia 1 0
    BNIP3L Genopedia 1 0
    TSC1 Genopedia 1 0
    CASP2 Genopedia 1 0
    CASP8 Genopedia 1 0
    CAV2 Genopedia 1 0
    TNFRSF10D Genopedia 1 0
    NAT1 Genopedia 1 0
    CD44 Genopedia 1 0
    CDC25C Genopedia 1 0
    IGF2BP1 Genopedia 1 0
    DNMT3A Genopedia 1 0
    ZHX2 Genopedia 1 0
    GHITM Genopedia 1 0
    IGHVIII-38-1 Genopedia 1 0
    GSTM4 Genopedia 1 0
    IFN1@ Genopedia 1 0
    IGFBP2 Genopedia 1 0
    MTR Genopedia 1 0
    MLL Genopedia 1 0
    NOTCH1 Genopedia 1 0
    PIK3R1 Genopedia 1 0
    POLH Genopedia 1 0
    SPP1 Genopedia 1 0
    UGT2A3 Genopedia 1 0
    NHEJ1 Genopedia 1 0
    RGS11 Genopedia 1 0
    TNFRSF10B Genopedia 1 0
    NR1I2 Genopedia 1 0
    FEN1 Genopedia 1 0
    RICTOR Genopedia 1 0
    GHR Genopedia 1 0
    IL28B Genopedia 1 0
    GSTM5 Genopedia 1 0
    SMAD1 Genopedia 1 0
    MC1R Genopedia 1 0
    BMF Genopedia 1 0
    IRS1 Genopedia 1 0
    MBD1 Genopedia 1 0
    ATP5A1 Genopedia 1 0
    PLK1 Genopedia 1 0
    RAN Genopedia 1 0
    HLA-A Genopedia 1 0
    APC Genopedia 1 0
    COX18 Genopedia 1 0
    RNASEN Genopedia 1 0
    SIRT3 Genopedia 1 0
    GH1 Genopedia 1 0
    CTNNB1 Genopedia 1 0
    CYP24A1 Genopedia 1 0
    FANCD2 Genopedia 1 0
    FGF2 Genopedia 1 0
    EZH1 Genopedia 1 0
    BCL2L10 Genopedia 1 0
    BCL2L11 Genopedia 1 0
    ATP5L Genopedia 1 0
    CYP27A1 Genopedia 1 0
    ASXL1 Genopedia 1 0
    GPX1 Genopedia 1 0
    XIAP Genopedia 1 0
    INS Genopedia 1 0
    SMAD7 Genopedia 1 0
    GEMIN4 Genopedia 1 0
    IGF2AS Genopedia 1 0
    PDGFRA Genopedia 1 0
    BAG1 Genopedia 1 0
    RGS3 Genopedia 1 0
    TAGLN Genopedia 1 0
    WT1 Genopedia 1 0
    CASR Genopedia 1 0
    RGS5 Genopedia 1 0
    TNFSF10 Genopedia 1 0
    ANGPTL1 Genopedia 1 0
    ACVR1B Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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