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HuGE Navigator|Phenopedia|PHGKB

Phenopedia


Genomic Instability

516 genes has been reported with Genomic Instability
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Associated Gene
Total Publication
Meta-analysis Publication
    BRAF Genopedia 160 4
    KRAS Genopedia 135 3
    TP53 Genopedia 75 1
    MLH1 Genopedia 62 4
    PIK3CA Genopedia 45 1
    MSH2 Genopedia 44 2
    MSH6 Genopedia 33 0
    NRAS Genopedia 21 0
    MTHFR Genopedia 20 0
    APC Genopedia 19 0
    PMS2 Genopedia 19 0
    PTEN Genopedia 18 1
    XRCC1 Genopedia 16 0
    BRCA1 Genopedia 16 0
    BRCA2 Genopedia 12 0
    CTNNB1 Genopedia 12 0
    EGFR Genopedia 12 1
    GSTM1 Genopedia 11 0
    XRCC6 Genopedia 10 0
    MTR Genopedia 10 0
    ERCC2 Genopedia 10 1
    TERT Genopedia 10 1
    MUTYH Genopedia 9 0
    CDKN2A Genopedia 9 0
    RBBP4 Genopedia 9 0
    SMAD4 Genopedia 8 0
    NBN Genopedia 8 0
    GSTT1 Genopedia 8 0
    ERBB2 Genopedia 8 0
    COX8A Genopedia 7 1
    ARID1A Genopedia 7 0
    GSTP1 Genopedia 6 0
    AKT1 Genopedia 6 0
    SHMT1 Genopedia 6 0
    TYMS Genopedia 6 0
    MTRR Genopedia 6 0
    RB1 Genopedia 5 0
    ERCC1 Genopedia 5 1
    OGG1 Genopedia 5 0
    NAT2 Genopedia 5 0
    ESR1 Genopedia 4 0
    FMR1 Genopedia 4 0
    LIG4 Genopedia 4 0
    XRCC5 Genopedia 4 0
    CCND1 Genopedia 4 0
    XRCC3 Genopedia 4 1
    JAK2 Genopedia 4 0
    RAD51 Genopedia 4 1
    APEX1 Genopedia 4 0
    TGFBR2 Genopedia 4 0
    CDH1 Genopedia 3 0
    CYP1A1 Genopedia 3 0
    FGFR2 Genopedia 3 0
    HRAS Genopedia 3 0
    IDH1 Genopedia 3 0
    TERC Genopedia 3 0
    TERF2 Genopedia 3 0
    IMPACT Genopedia 3 0
    ATM Genopedia 3 0
    MAP2K1 Genopedia 3 0
    CD274 Genopedia 3 0
    CD8A Genopedia 3 0
    MGMT Genopedia 3 0
    EPHX1 Genopedia 3 0
    XRCC4 Genopedia 3 0
    AURKA Genopedia 3 0
    STK11 Genopedia 3 0
    APOE Genopedia 3 0
    ERCC5 Genopedia 3 1
    MDM2 Genopedia 3 0
    VDR Genopedia 3 0
    RFC1 Genopedia 3 0
    BRIP1 Genopedia 3 0
    ALDH2 Genopedia 3 0
    MRE11A Genopedia 3 0
    BAX Genopedia 3 0
    RET Genopedia 3 0
    SOD2 Genopedia 3 0
    PTTG1 Genopedia 3 0
    BUB1 Genopedia 2 0
    SYK Genopedia 2 0
    BAK1 Genopedia 2 0
    SOD1 Genopedia 2 0
    C9orf72 Genopedia 2 1
    EP300 Genopedia 2 0
    CSMD1 Genopedia 2 0
    TBP Genopedia 2 0
    DHFR Genopedia 2 0
    FBXW7 Genopedia 2 0
    NOTCH1 Genopedia 2 0
    PARK2 Genopedia 2 0
    IL1RN Genopedia 2 0
    LOC390714 Genopedia 2 0
    AKT2 Genopedia 2 0
    CYP1B1 Genopedia 2 0
    SMAD7 Genopedia 2 0
    TNKS2 Genopedia 2 0
    ABCG2 Genopedia 2 0
    ERCC6 Genopedia 2 0
    FLT3 Genopedia 2 0
    Braf Genopedia 2 0
    CHEK1 Genopedia 2 0
    ATXN3 Genopedia 2 0
    AR Genopedia 2 0
    PDCD1 Genopedia 2 0
    ATR Genopedia 2 0
    HTT Genopedia 2 0
    MAD2L1 Genopedia 2 0
    MTHFD1 Genopedia 2 0
    CDKN2B Genopedia 2 0
    DAPK1 Genopedia 2 0
    FEN1 Genopedia 2 1
    FGA Genopedia 2 0
    TGFBR1 Genopedia 2 0
    WRN Genopedia 2 0
    CBS Genopedia 2 0
    RTEL1 Genopedia 2 0
    TNF Genopedia 2 0
    MET Genopedia 2 0
    TEP1 Genopedia 2 0
    ZHX2 Genopedia 2 0
    ODZ1 Genopedia 2 0
    NF1 Genopedia 2 0
    SIL1 Genopedia 2 0
    RPA3 Genopedia 2 0
    IL6 Genopedia 2 0
    POLD1 Genopedia 2 0
    COMT Genopedia 2 0
    JAK1 Genopedia 2 0
    KIT Genopedia 2 0
    MIR21 Genopedia 2 0
    POT1 Genopedia 2 0
    CDKN1A Genopedia 2 0
    CYP2E1 Genopedia 2 0
    HIF1A Genopedia 2 0
    TERF1 Genopedia 2 0
    XPC Genopedia 2 1
    BIRC7 Genopedia 1 0
    VPS37B Genopedia 1 0
    OBFC1 Genopedia 1 0
    FZD6 Genopedia 1 0
    MAD1L1 Genopedia 1 0
    CASR Genopedia 1 0
    DUOXA1 Genopedia 1 0
    EXO1 Genopedia 1 0
    SNCAIP Genopedia 1 0
    GREB1 Genopedia 1 0
    WT1 Genopedia 1 0
    NFATC1 Genopedia 1 0
    HSPA14 Genopedia 1 0
    PDGFRA Genopedia 1 0
    PIK3C2A Genopedia 1 0
    WNT4 Genopedia 1 0
    UGT1A6 Genopedia 1 0
    PBRM1 Genopedia 1 0
    PPP2R2B Genopedia 1 0
    PRKCI Genopedia 1 0
    PRKDC Genopedia 1 0
    PRDM9 Genopedia 1 0
    PTGS2 Genopedia 1 0
    RAD23B Genopedia 1 0
    ATXN7 Genopedia 1 0
    SERPINB3 Genopedia 1 0
    SLC5A3 Genopedia 1 0
    SMARCA4 Genopedia 1 0
    ND1 Genopedia 1 0
    TBCE Genopedia 1 0
    CYP17A1 Genopedia 1 0
    GADD45A Genopedia 1 0
    DDX5 Genopedia 1 0
    ARID2 Genopedia 1 0
    ESR2 Genopedia 1 0
    ALKBH3 Genopedia 1 0
    FGFR3 Genopedia 1 0
    ADAR Genopedia 1 0
    CENPF Genopedia 1 0
    EHMT2 Genopedia 1 0
    TOPBP1 Genopedia 1 0
    CYP2C19 Genopedia 1 0
    LOC100508689 Genopedia 1 0
    ABCC4 Genopedia 1 0
    AMD1 Genopedia 1 0
    GPX1 Genopedia 1 0
    SETD2 Genopedia 1 0
    GSTA2 Genopedia 1 0
    GSTM3 Genopedia 1 0
    SLC9A8 Genopedia 1 0
    CRTC1 Genopedia 1 0
    Egfr Genopedia 1 0
    Kras Genopedia 1 0
    MPZ Genopedia 1 0
    LEPR Genopedia 1 0
    IGHV@ Genopedia 1 0
    HUS1 Genopedia 1 0
    AASDH Genopedia 1 0
    MUC15 Genopedia 1 0
    CTNNA1 Genopedia 1 0
    CDH10 Genopedia 1 0
    NDC80 Genopedia 1 0
    SMC2 Genopedia 1 0
    CHEK2 Genopedia 1 0
    TREX1 Genopedia 1 0
    NLRP3 Genopedia 1 0
    ADH1B Genopedia 1 0
    CYP2C9 Genopedia 1 0
    DDX11 Genopedia 1 0
    DKC1 Genopedia 1 0
    SLC36A1 Genopedia 1 0
    MMRN1 Genopedia 1 0
    FOXO1 Genopedia 1 0
    SMUG1 Genopedia 1 0
    VPS41 Genopedia 1 0
    GNAS Genopedia 1 0
    IGKV2-29 Genopedia 1 0
    HMOX1 Genopedia 1 0
    POLG Genopedia 1 0
    DCHS2 Genopedia 1 0
    ATG2B Genopedia 1 0
    RIF1 Genopedia 1 0
    NHP2 Genopedia 1 0
    PTCH1 Genopedia 1 0
    ARID1B Genopedia 1 0
    PTPRS Genopedia 1 0
    IRS1 Genopedia 1 0
    ICAM1 Genopedia 1 0
    DCAF12L2 Genopedia 1 0
    MRC1 Genopedia 1 0
    MSMB Genopedia 1 0
    MTM1 Genopedia 1 0
    ATXN1 Genopedia 1 0
    ATXN8OS Genopedia 1 0
    SFRP2 Genopedia 1 0
    SOD3 Genopedia 1 0
    ARID4A Genopedia 1 0
    Brca1 Genopedia 1 0
    PDGFRB Genopedia 1 0
    ABCB1 Genopedia 1 0
    RAD52 Genopedia 1 0
    KRT82 Genopedia 1 0
    TTR Genopedia 1 0
    MCPH1 Genopedia 1 0
    EHMT1 Genopedia 1 0
    USP9X Genopedia 1 0
    AURKB Genopedia 1 0
    COX5A Genopedia 1 0
    RECQL5 Genopedia 1 0
    DOCK4 Genopedia 1 0
    CDC25A Genopedia 1 0
    WDR3 Genopedia 1 0
    ERCC8 Genopedia 1 0
    COL11A1 Genopedia 1 0
    Ebp Genopedia 1 0
    VPS13B Genopedia 1 0
    CYP11A1 Genopedia 1 0
    AGTR1 Genopedia 1 0
    MORC2 Genopedia 1 0
    PDS5B Genopedia 1 0
    TARDBP Genopedia 1 0
    IGKV2-23 Genopedia 1 0
    IGF1R Genopedia 1 0
    ITGA7 Genopedia 1 0
    MBP Genopedia 1 0
    DDR2 Genopedia 1 0
    SYCP3 Genopedia 1 0
    SERPINE1 Genopedia 1 0
    VPS54 Genopedia 1 0
    VPS13C Genopedia 1 0
    TMLHE Genopedia 1 0
    TP53BP1 Genopedia 1 0
    TTK Genopedia 1 0
    NOP10 Genopedia 1 0
    ZBTB2 Genopedia 1 0
    REV3L Genopedia 1 0
    CHTF18 Genopedia 1 0
    CENPH Genopedia 1 0
    SLC19A1 Genopedia 1 0
    BMPR2 Genopedia 1 0
    TCF7L2 Genopedia 1 0
    CAT Genopedia 1 0
    SSH2 Genopedia 1 0
    TNKS Genopedia 1 0
    MBTPS1 Genopedia 1 0
    MTMR3 Genopedia 1 0
    CD44 Genopedia 1 0
    STARD13 Genopedia 1 0
    CEP135 Genopedia 1 0
    MED13 Genopedia 1 0
    FOSL1 Genopedia 1 0
    TRRAP Genopedia 1 0
    CUL2 Genopedia 1 0
    PTPN5 Genopedia 1 0
    VEGFB Genopedia 1 0
    BUB1B Genopedia 1 0
    RECQL Genopedia 1 0
    TTTY2 Genopedia 1 0
    ROBO2 Genopedia 1 0
    RPL22 Genopedia 1 0
    BHMT Genopedia 1 0
    B2M Genopedia 1 0
    C11orf30 Genopedia 1 0
    PSMB8 Genopedia 1 0
    RAD51B Genopedia 1 0
    CDK7 Genopedia 1 0
    ATRX Genopedia 1 0
    CHFR Genopedia 1 0
    ATG9B Genopedia 1 0
    IGKV3-20 Genopedia 1 0
    IGKV2-19 Genopedia 1 0
    IGKV2-18 Genopedia 1 0
    IGKV1-22 Genopedia 1 0
    DAXX Genopedia 1 0
    Kras Genopedia 1 0
    DUT Genopedia 1 0
    AHCY Genopedia 1 0
    EPHB2 Genopedia 1 0
    FAF1 Genopedia 1 0
    MRGPRX4 Genopedia 1 0
    TAF1L Genopedia 1 0
    CRKL Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    CSF3R Genopedia 1 0
    CYP2A6 Genopedia 1 0
    FAAH2 Genopedia 1 0
    MUC7 Genopedia 1 0
    MAT2A Genopedia 1 0
    PAK1 Genopedia 1 0
    FOXP3 Genopedia 1 0
    PDHB Genopedia 1 0
    FOXA1 Genopedia 1 0
    HSPA4 Genopedia 1 0
    IL1B Genopedia 1 0
    MIR31 Genopedia 1 0
    GSTT2 Genopedia 1 0
    HARS Genopedia 1 0
    FANCC Genopedia 1 0
    tor Genopedia 1 0
    MYNN Genopedia 1 0
    CMAS Genopedia 1 1
    BCL9 Genopedia 1 0
    ROBO1 Genopedia 1 0
    BLM Genopedia 1 0
    CDH24 Genopedia 1 0
    GAR1 Genopedia 1 0
    TNFRSF1B Genopedia 1 0
    CACNA1A Genopedia 1 0
    TTPAL Genopedia 1 0
    CUBN Genopedia 1 0
    PDCD1LG2 Genopedia 1 0
    SPOP Genopedia 1 0
    ANTXR1 Genopedia 1 0
    ACVR2A Genopedia 1 0
    ATG5 Genopedia 1 0
    KNTC1 Genopedia 1 0
    HDAC4 Genopedia 1 0
    CDK1 Genopedia 1 0
    EPCAM Genopedia 1 0
    MUC4 Genopedia 1 0
    NF2 Genopedia 1 0
    NPM1 Genopedia 1 0
    RRM2B Genopedia 1 0
    GALNT9 Genopedia 1 0
    HIST1H1E Genopedia 1 0
    HIC1 Genopedia 1 0
    BIRC5 Genopedia 1 0
    IGFBP3 Genopedia 1 0
    IL8 Genopedia 1 0
    Chek2 Genopedia 1 0
    GLT1D1 Genopedia 1 0
    WDR16 Genopedia 1 0
    EME1 Genopedia 1 0
    CYP1A2 Genopedia 1 0
    TCEAL6 Genopedia 1 0
    ACE Genopedia 1 0
    NQO1 Genopedia 1 0
    DNMT1 Genopedia 1 0
    Tp53 Genopedia 1 0
    FUS Genopedia 1 0
    GLI1 Genopedia 1 0
    ZNF292 Genopedia 1 0
    SETD1B Genopedia 1 0
    AKR1B1 Genopedia 1 0
    PRDM2 Genopedia 1 0
    AXIN1 Genopedia 1 0
    AXIN2 Genopedia 1 0
    MCEE Genopedia 1 0
    BANF1 Genopedia 1 0
    ATG12 Genopedia 1 0
    BUB3 Genopedia 1 0
    XRCC2 Genopedia 1 0
    CHD8 Genopedia 1 0
    RANBP2 Genopedia 1 0
    NEK2 Genopedia 1 0
    NFE2L2 Genopedia 1 0
    MC4R Genopedia 1 0
    MALAT1 Genopedia 1 0
    GIF Genopedia 1 0
    APBA2 Genopedia 1 0
    IGF1 Genopedia 1 0
    APIP Genopedia 1 0
    WBP5 Genopedia 1 0
    GHRL Genopedia 1 0
    PPARG Genopedia 1 0
    CHD7 Genopedia 1 0
    ASH1L Genopedia 1 0
    BRUNOL4 Genopedia 1 0
    C16orf82 Genopedia 1 0
    DNMT3B Genopedia 1 0
    ATN1 Genopedia 1 0
    AGT Genopedia 1 0
    Pik3ca Genopedia 1 0
    OR9Q2 Genopedia 1 0
    ZC3H13 Genopedia 1 0
    RAD50 Genopedia 1 0
    Scrib Genopedia 1 0
    PTPN21 Genopedia 1 0
    ZWINT Genopedia 1 0
    RASSF1 Genopedia 1 0
    ADH1C Genopedia 1 0
    ADRA2C Genopedia 1 0
    CUX1 Genopedia 1 0
    LEP Genopedia 1 0
    LIG1 Genopedia 1 0
    MIRLET7B Genopedia 1 0
    MAP1B Genopedia 1 0
    IL4 Genopedia 1 0
    IL10 Genopedia 1 0
    APBA1 Genopedia 1 0
    IFNG Genopedia 1 0
    LAP3 Genopedia 1 0
    PMS1 Genopedia 1 0
    SSH1 Genopedia 1 0
    RBFOX1 Genopedia 1 0
    MEN1 Genopedia 1 0
    SIRT1 Genopedia 1 0
    FRA6E Genopedia 1 0
    COPD Genopedia 1 0
    ALCAM Genopedia 1 0
    FGFR1 Genopedia 1 0
    VPS13A Genopedia 1 0
    CTSB Genopedia 1 0
    SGOL1 Genopedia 1 0
    CYP2C18 Genopedia 1 0
    CYP11B2 Genopedia 1 0
    ADA Genopedia 1 0
    CEACAM5 Genopedia 1 0
    YME1L1 Genopedia 1 0
    HSPH1 Genopedia 1 0
    COL11A2 Genopedia 1 0
    BTK Genopedia 1 0
    XPA Genopedia 1 0
    RPS6KL1 Genopedia 1 0
    SETDB2 Genopedia 1 0
    BMP1 Genopedia 1 0
    BMPR1A Genopedia 1 0
    ND5 Genopedia 1 0
    RXRA Genopedia 1 0
    SALL1 Genopedia 1 0
    ATXN2 Genopedia 1 0
    TUBB6 Genopedia 1 0
    TEAD2 Genopedia 1 0
    PSRC1 Genopedia 1 0
    RHPN2 Genopedia 1 0
    VPS4B Genopedia 1 0
    ESPL1 Genopedia 1 0
    RAPGEF5 Genopedia 1 0
    MED12 Genopedia 1 0
    UQCRHL Genopedia 1 0
    GTF2H3 Genopedia 1 0
    HES1 Genopedia 1 0
    LAMA5 Genopedia 1 0
    MAP3K11 Genopedia 1 0
    PLXNA1 Genopedia 1 0
    POLE Genopedia 1 0
    POMC Genopedia 1 0
    RNF43 Genopedia 1 0
    ZWILCH Genopedia 1 0
    PPP2R1A Genopedia 1 0
    PPP2R5C Genopedia 1 0
    VPS35 Genopedia 1 0
    MAP2K2 Genopedia 1 0
    PDXDC1 Genopedia 1 0
    ADNP Genopedia 1 0
    ABL1 Genopedia 1 0
    Cdkn2a Genopedia 1 0
    NEIL2 Genopedia 1 0
    GCDH Genopedia 1 0
    GLDC Genopedia 1 0
    GSTA4 Genopedia 1 0
    DEL13Q14 Genopedia 1 0
    CDKN2C Genopedia 1 0
    CEACAM3 Genopedia 1 0
    ESCO1 Genopedia 1 0
    C11orf93 Genopedia 1 0
    CRYBB1 Genopedia 1 0
    DACT3 Genopedia 1 0
    VPS37D Genopedia 1 0
    CD55 Genopedia 1 0
    DMPK Genopedia 1 0
    DMRT1 Genopedia 1 0
    AGXT Genopedia 1 0
    SNCA Genopedia 1 0
    RPA1 Genopedia 1 0
    ZNF350 Genopedia 1 0
    TAF1 Genopedia 1 0
    TAP1 Genopedia 1 0
    TCN2 Genopedia 1 0
    U2AF1 Genopedia 1 0
    UNG Genopedia 1 0
    STAT3 Genopedia 1 0
    BCAR1 Genopedia 1 0
    Cdkn1b Genopedia 1 0
    CDC14A Genopedia 1 0
    IRS2 Genopedia 1 0
    KAT2B Genopedia 1 0
    MBD4 Genopedia 1 0
    NAT1 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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