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HuGE Navigator|Phenopedia|PHGKB

Phenopedia


Genomic Instability

572 genes has been reported with Genomic Instability
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Associated Gene
Total Publication
Meta-analysis Publication
    BRAF Genopedia 171 4
    KRAS Genopedia 148 3
    TP53 Genopedia 90 1
    MLH1 Genopedia 66 4
    PIK3CA Genopedia 51 1
    MSH2 Genopedia 45 2
    MSH6 Genopedia 35 0
    NRAS Genopedia 23 0
    APC Genopedia 22 0
    PMS2 Genopedia 21 0
    PTEN Genopedia 20 1
    MTHFR Genopedia 20 0
    XRCC1 Genopedia 18 0
    BRCA1 Genopedia 17 0
    BRCA2 Genopedia 15 0
    CTNNB1 Genopedia 15 0
    EGFR Genopedia 14 1
    RBBP4 Genopedia 14 0
    ERBB2 Genopedia 13 0
    ERCC2 Genopedia 11 1
    GSTM1 Genopedia 11 0
    XRCC6 Genopedia 10 0
    MTR Genopedia 10 0
    MUTYH Genopedia 10 0
    TERT Genopedia 10 1
    ARID1A Genopedia 9 0
    NBN Genopedia 9 0
    SMAD4 Genopedia 9 0
    CDKN2A Genopedia 9 0
    GSTT1 Genopedia 8 0
    GSTP1 Genopedia 7 0
    COX8A Genopedia 7 1
    AKT1 Genopedia 7 0
    MTRR Genopedia 6 0
    OGG1 Genopedia 6 0
    TYMS Genopedia 6 0
    SHMT1 Genopedia 6 0
    RB1 Genopedia 6 0
    RAD51 Genopedia 5 1
    XRCC3 Genopedia 5 1
    ATM Genopedia 5 0
    CD274 Genopedia 5 0
    ERCC1 Genopedia 5 1
    NAT2 Genopedia 5 0
    ESR1 Genopedia 4 0
    FMR1 Genopedia 4 0
    JAK2 Genopedia 4 0
    IDH1 Genopedia 4 0
    APEX1 Genopedia 4 0
    LIG4 Genopedia 4 0
    XRCC5 Genopedia 4 0
    BRIP1 Genopedia 4 0
    CCND1 Genopedia 4 0
    SOD2 Genopedia 4 0
    TGFBR2 Genopedia 4 0
    VDR Genopedia 3 0
    TERF2 Genopedia 3 0
    AURKA Genopedia 3 0
    STK11 Genopedia 3 0
    TERC Genopedia 3 0
    SOD1 Genopedia 3 0
    RFC1 Genopedia 3 0
    RET Genopedia 3 0
    BAX Genopedia 3 0
    MAP2K1 Genopedia 3 0
    POLD1 Genopedia 3 0
    IMPACT Genopedia 3 0
    XRCC4 Genopedia 3 0
    PTTG1 Genopedia 3 0
    CD8A Genopedia 3 0
    CDH1 Genopedia 3 0
    MRE11A Genopedia 3 0
    MDM2 Genopedia 3 0
    MGMT Genopedia 3 0
    NF1 Genopedia 3 0
    PDCD1 Genopedia 3 0
    RTEL1 Genopedia 3 0
    HRAS Genopedia 3 0
    APOE Genopedia 3 0
    FLT3 Genopedia 3 0
    GNAS Genopedia 3 0
    POT1 Genopedia 3 0
    ALDH2 Genopedia 3 0
    FGFR2 Genopedia 3 0
    ERCC5 Genopedia 3 1
    CYP1A1 Genopedia 3 0
    EPHX1 Genopedia 3 0
    C9orf72 Genopedia 2 1
    EP300 Genopedia 2 0
    ERCC6 Genopedia 2 0
    AKT2 Genopedia 2 0
    CDKN1A Genopedia 2 0
    DHFR Genopedia 2 0
    CYP1B1 Genopedia 2 0
    AGT Genopedia 2 0
    FEN1 Genopedia 2 1
    FGA Genopedia 2 0
    FANCC Genopedia 2 0
    FAT1 Genopedia 2 0
    ZHX2 Genopedia 2 0
    LOC100508689 Genopedia 2 0
    RAD50 Genopedia 2 0
    ODZ1 Genopedia 2 0
    CDX2 Genopedia 2 0
    CDKN2B Genopedia 2 0
    CHEK1 Genopedia 2 0
    CHEK2 Genopedia 2 0
    Braf Genopedia 2 0
    COMT Genopedia 2 0
    CYP2E1 Genopedia 2 0
    DAPK1 Genopedia 2 0
    GPX1 Genopedia 2 0
    HTT Genopedia 2 0
    IL6 Genopedia 2 0
    JAK1 Genopedia 2 0
    IL1RN Genopedia 2 0
    AR Genopedia 2 0
    HIF1A Genopedia 2 0
    PDGFRB Genopedia 2 0
    PARK2 Genopedia 2 0
    FOXP3 Genopedia 2 0
    NF2 Genopedia 2 0
    NOTCH1 Genopedia 2 0
    MYC Genopedia 2 0
    ATXN3 Genopedia 2 0
    MET Genopedia 2 0
    MTHFD1 Genopedia 2 0
    LOC390714 Genopedia 2 0
    SMAD7 Genopedia 2 0
    MIR21 Genopedia 2 0
    KIT Genopedia 2 0
    MAD2L1 Genopedia 2 0
    XPC Genopedia 2 1
    CAT Genopedia 2 0
    TET1 Genopedia 2 0
    TNKS2 Genopedia 2 0
    CBS Genopedia 2 0
    ABCG2 Genopedia 2 0
    PIK3R1 Genopedia 2 0
    PPP2R1A Genopedia 2 0
    ATR Genopedia 2 0
    BAK1 Genopedia 2 0
    RAD51C Genopedia 2 0
    PRKDC Genopedia 2 0
    B2M Genopedia 2 0
    BLM Genopedia 2 0
    RPA3 Genopedia 2 0
    SIL1 Genopedia 2 0
    FBXW7 Genopedia 2 0
    CSMD1 Genopedia 2 0
    TERF1 Genopedia 2 0
    BUB1 Genopedia 2 0
    BUB1B Genopedia 2 0
    TEP1 Genopedia 2 0
    TBP Genopedia 2 0
    SYK Genopedia 2 0
    TAF1 Genopedia 2 0
    TGFBR1 Genopedia 2 0
    WRN Genopedia 2 0
    TNF Genopedia 2 0
    TNFRSF1B Genopedia 1 0
    U2AF1 Genopedia 1 0
    UNG Genopedia 1 0
    WT1 Genopedia 1 0
    XPA Genopedia 1 0
    VEGFB Genopedia 1 0
    TGFB1 Genopedia 1 0
    TP53BP1 Genopedia 1 0
    TTK Genopedia 1 0
    TTR Genopedia 1 0
    TAP1 Genopedia 1 0
    TBCE Genopedia 1 0
    STAT3 Genopedia 1 0
    ND5 Genopedia 1 0
    ND1 Genopedia 1 0
    TCF7L2 Genopedia 1 0
    ZEB1 Genopedia 1 0
    TCN2 Genopedia 1 0
    BTK Genopedia 1 0
    TRBV20OR9-2 Genopedia 1 0
    CDH24 Genopedia 1 0
    SOD3 Genopedia 1 0
    SOX9 Genopedia 1 0
    BMP1 Genopedia 1 0
    CENPH Genopedia 1 0
    SLC5A3 Genopedia 1 0
    BMPR1A Genopedia 1 0
    SLC19A1 Genopedia 1 0
    BMPR2 Genopedia 1 0
    SMARCA4 Genopedia 1 0
    SNCA Genopedia 1 0
    RPL22 Genopedia 1 0
    RXRA Genopedia 1 0
    SALL1 Genopedia 1 0
    ATXN1 Genopedia 1 0
    ATXN2 Genopedia 1 0
    ATXN7 Genopedia 1 0
    ATXN8OS Genopedia 1 0
    SERPINB3 Genopedia 1 0
    BHMT Genopedia 1 0
    CHTF18 Genopedia 1 0
    TSPYL2 Genopedia 1 0
    SFRP2 Genopedia 1 0
    REV3L Genopedia 1 0
    TTTY2 Genopedia 1 0
    BCL9 Genopedia 1 0
    ROBO1 Genopedia 1 0
    ROBO2 Genopedia 1 0
    RPA1 Genopedia 1 0
    BRUNOL4 Genopedia 1 0
    C11orf30 Genopedia 1 0
    PSMB8 Genopedia 1 0
    PRDM9 Genopedia 1 0
    PDXP Genopedia 1 0
    TWSG1 Genopedia 1 0
    PTCH1 Genopedia 1 0
    MAPK1 Genopedia 1 0
    PIK3CD Genopedia 1 0
    AICDA Genopedia 1 0
    PTGS2 Genopedia 1 0
    ARID1B Genopedia 1 0
    SHROOM3 Genopedia 1 0
    ZBTB2 Genopedia 1 0
    CHD8 Genopedia 1 0
    RAD51B Genopedia 1 0
    RAD52 Genopedia 1 0
    RANBP2 Genopedia 1 0
    BARD1 Genopedia 1 0
    PTPRS Genopedia 1 0
    MAP2K2 Genopedia 1 0
    RAD23B Genopedia 1 0
    ARID4A Genopedia 1 0
    BCL2 Genopedia 1 0
    RECQL Genopedia 1 0
    ZNF350 Genopedia 1 0
    UGT1A6 Genopedia 1 0
    ATRX Genopedia 1 0
    PPARG Genopedia 1 0
    RBFOX1 Genopedia 1 0
    DCHS2 Genopedia 1 0
    VPS13C Genopedia 1 0
    RNF43 Genopedia 1 0
    ZWILCH Genopedia 1 0
    ATG2B Genopedia 1 0
    POLE Genopedia 1 0
    POLG Genopedia 1 0
    WNT4 Genopedia 1 0
    POMC Genopedia 1 0
    GAR1 Genopedia 1 0
    SSH1 Genopedia 1 0
    RIF1 Genopedia 1 0
    PBRM1 Genopedia 1 0
    PPP2R2B Genopedia 1 0
    TMLHE Genopedia 1 0
    PPP2R5C Genopedia 1 0
    PLCG1 Genopedia 1 0
    PLXNA1 Genopedia 1 0
    PMS1 Genopedia 1 0
    NOP10 Genopedia 1 0
    CHD7 Genopedia 1 0
    NHP2 Genopedia 1 0
    VPS35 Genopedia 1 0
    CHFR Genopedia 1 0
    PRKCI Genopedia 1 0
    ASH1L Genopedia 1 0
    PRKCQ Genopedia 1 0
    MYNN Genopedia 1 0
    CMAS Genopedia 1 1
    GSTO1 Genopedia 1 0
    ATG5 Genopedia 1 0
    VPS4B Genopedia 1 0
    BCAR1 Genopedia 1 0
    CD44 Genopedia 1 0
    SNCAIP Genopedia 1 0
    CEP135 Genopedia 1 0
    GREB1 Genopedia 1 0
    ESPL1 Genopedia 1 0
    DOCK4 Genopedia 1 0
    KNTC1 Genopedia 1 0
    HDAC4 Genopedia 1 0
    RAPGEF5 Genopedia 1 0
    CDK1 Genopedia 1 0
    CDC25A Genopedia 1 0
    CDC27 Genopedia 1 0
    MED12 Genopedia 1 0
    MED13 Genopedia 1 0
    BANF1 Genopedia 1 0
    KAT2B Genopedia 1 0
    MTMR3 Genopedia 1 0
    MBD4 Genopedia 1 0
    CCNE1 Genopedia 1 0
    NAT1 Genopedia 1 0
    DUOXA1 Genopedia 1 0
    STARD13 Genopedia 1 0
    USP8 Genopedia 1 0
    ATG12 Genopedia 1 0
    EXO1 Genopedia 1 0
    BUB3 Genopedia 1 0
    ACVR2A Genopedia 1 0
    CD4 Genopedia 1 0
    AURKB Genopedia 1 0
    PDCD1LG2 Genopedia 1 0
    FOSL1 Genopedia 1 0
    USP9X Genopedia 1 0
    XRCC2 Genopedia 1 0
    CACNA1A Genopedia 1 0
    ZNF217 Genopedia 1 0
    PRDM2 Genopedia 1 0
    TTPAL Genopedia 1 0
    BIRC7 Genopedia 1 0
    MCPH1 Genopedia 1 0
    VPS37B Genopedia 1 0
    PALB2 Genopedia 1 0
    EHMT1 Genopedia 1 0
    WLS Genopedia 1 0
    OBFC1 Genopedia 1 0
    CUBN Genopedia 1 0
    SPOP Genopedia 1 0
    CASP8 Genopedia 1 0
    FAM175A Genopedia 1 0
    ANTXR1 Genopedia 1 0
    CUL2 Genopedia 1 0
    CASR Genopedia 1 0
    TUBB6 Genopedia 1 0
    TEAD2 Genopedia 1 0
    MCEE Genopedia 1 0
    TRRAP Genopedia 1 0
    AXIN1 Genopedia 1 0
    AXIN2 Genopedia 1 0
    BAP1 Genopedia 1 0
    FZD6 Genopedia 1 0
    Cdkn1b Genopedia 1 0
    RPS6KL1 Genopedia 1 0
    MAD1L1 Genopedia 1 0
    SETDB2 Genopedia 1 0
    PSRC1 Genopedia 1 0
    PTPN5 Genopedia 1 0
    RHPN2 Genopedia 1 0
    SSH2 Genopedia 1 0
    CDC14A Genopedia 1 0
    RUNX3 Genopedia 1 0
    SOCS1 Genopedia 1 0
    TNKS Genopedia 1 0
    IRS2 Genopedia 1 0
    MBTPS1 Genopedia 1 0
    COX5A Genopedia 1 0
    RECQL5 Genopedia 1 0
    MIR31 Genopedia 1 0
    EPCAM Genopedia 1 0
    MAP1B Genopedia 1 0
    MAT2A Genopedia 1 0
    MBP Genopedia 1 0
    MC4R Genopedia 1 0
    LAMA5 Genopedia 1 0
    LEP Genopedia 1 0
    LEPR Genopedia 1 0
    LIG1 Genopedia 1 0
    MIRLET7B Genopedia 1 0
    KRT7 Genopedia 1 0
    KRT82 Genopedia 1 0
    MTM1 Genopedia 1 0
    UQCRHL Genopedia 1 0
    MSMB Genopedia 1 0
    MEN1 Genopedia 1 0
    MAP3K11 Genopedia 1 0
    MPZ Genopedia 1 0
    MRC1 Genopedia 1 0
    MYCN Genopedia 1 0
    NEK2 Genopedia 1 0
    MUC4 Genopedia 1 0
    MUC7 Genopedia 1 0
    NPM1 Genopedia 1 0
    DDR2 Genopedia 1 0
    NFATC1 Genopedia 1 0
    NFE2L2 Genopedia 1 0
    LAP3 Genopedia 1 0
    APIP Genopedia 1 0
    HSPA14 Genopedia 1 0
    WBP5 Genopedia 1 0
    Brca1 Genopedia 1 0
    RRM2B Genopedia 1 0
    SYCP3 Genopedia 1 0
    SERPINE1 Genopedia 1 0
    PAK1 Genopedia 1 0
    GALNT9 Genopedia 1 0
    PDHB Genopedia 1 0
    GHRL Genopedia 1 0
    VPS54 Genopedia 1 0
    PDGFRA Genopedia 1 0
    PGR Genopedia 1 0
    ABCB1 Genopedia 1 0
    PIK3C2A Genopedia 1 0
    HLA-G Genopedia 1 0
    HMOX1 Genopedia 1 0
    FOXA1 Genopedia 1 0
    APBA1 Genopedia 1 0
    APBA2 Genopedia 1 0
    IFNG Genopedia 1 0
    IGF1 Genopedia 1 0
    HES1 Genopedia 1 0
    HSPA4 Genopedia 1 0
    BIRC5 Genopedia 1 0
    HTR2B Genopedia 1 0
    HUS1 Genopedia 1 0
    ICAM1 Genopedia 1 0
    DCAF12L2 Genopedia 1 0
    ITGA7 Genopedia 1 0
    IL4 Genopedia 1 0
    MALAT1 Genopedia 1 0
    IL8 Genopedia 1 0
    IL10 Genopedia 1 0
    IRS1 Genopedia 1 0
    IGF1R Genopedia 1 0
    IGFBP3 Genopedia 1 0
    IGHV@ Genopedia 1 0
    IL1B Genopedia 1 0
    HIC1 Genopedia 1 0
    GSTT2 Genopedia 1 0
    GTF2H3 Genopedia 1 0
    HIST1H1E Genopedia 1 0
    HARS Genopedia 1 0
    BCL9L Genopedia 1 0
    ATG9B Genopedia 1 0
    VPS13A Genopedia 1 0
    SLC9A8 Genopedia 1 0
    GSTA2 Genopedia 1 0
    GSTA4 Genopedia 1 0
    GSTM3 Genopedia 1 0
    GPX3 Genopedia 1 0
    GPX4 Genopedia 1 0
    IGKV3-20 Genopedia 1 0
    IGKV2-29 Genopedia 1 0
    IGKV2-23 Genopedia 1 0
    IGKV2-19 Genopedia 1 0
    IGKV2-18 Genopedia 1 0
    IGKV1-22 Genopedia 1 0
    SETD2 Genopedia 1 0
    COPD Genopedia 1 0
    AMD1 Genopedia 1 0
    GATA6 Genopedia 1 0
    GCDH Genopedia 1 0
    GIF Genopedia 1 0
    VPS41 Genopedia 1 0
    GLDC Genopedia 1 0
    GLI1 Genopedia 1 0
    GLO1 Genopedia 1 0
    DAXX Genopedia 1 0
    C16orf82 Genopedia 1 0
    ACE Genopedia 1 0
    GADD45A Genopedia 1 0
    DDX5 Genopedia 1 0
    DDX11 Genopedia 1 0
    Kras Genopedia 1 0
    VPS13B Genopedia 1 0
    CYP11A1 Genopedia 1 0
    CYP11B2 Genopedia 1 0
    FAAH2 Genopedia 1 0
    CYP17A1 Genopedia 1 0
    TCEAL6 Genopedia 1 0
    CD55 Genopedia 1 0
    AASDH Genopedia 1 0
    TOPBP1 Genopedia 1 0
    PTPN21 Genopedia 1 0
    CTSB Genopedia 1 0
    SGOL1 Genopedia 1 0
    ADRA2C Genopedia 1 0
    CUX1 Genopedia 1 0
    Ebp Genopedia 1 0
    TAF1L Genopedia 1 0
    CRKL Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    CRYBB1 Genopedia 1 0
    PARP1 Genopedia 1 0
    MUC15 Genopedia 1 0
    CSF3R Genopedia 1 0
    GLT1D1 Genopedia 1 0
    WDR16 Genopedia 1 0
    EME1 Genopedia 1 0
    DACT3 Genopedia 1 0
    GLIS1 Genopedia 1 0
    CTNNA1 Genopedia 1 0
    TREX1 Genopedia 1 0
    Chek2 Genopedia 1 0
    NLRP3 Genopedia 1 0
    ESCO1 Genopedia 1 0
    ERCC8 Genopedia 1 0
    MRGPRX4 Genopedia 1 0
    GSTO2 Genopedia 1 0
    C11orf93 Genopedia 1 0
    FRMD6 Genopedia 1 0
    ADH1B Genopedia 1 0
    ADH1C Genopedia 1 0
    COL11A1 Genopedia 1 0
    COL11A2 Genopedia 1 0
    FAF1 Genopedia 1 0
    ZWINT Genopedia 1 0
    RASSF1 Genopedia 1 0
    CDKN2C Genopedia 1 0
    NDC80 Genopedia 1 0
    ADAR Genopedia 1 0
    CEACAM5 Genopedia 1 0
    Scrib Genopedia 1 0
    SMC2 Genopedia 1 0
    CENPF Genopedia 1 0
    YME1L1 Genopedia 1 0
    STAG2 Genopedia 1 0
    HSPH1 Genopedia 1 0
    CEACAM3 Genopedia 1 0
    WDR3 Genopedia 1 0
    EHMT2 Genopedia 1 0
    CDK7 Genopedia 1 0
    ABCC4 Genopedia 1 0
    DEL13Q14 Genopedia 1 0
    CDH10 Genopedia 1 0
    ADA Genopedia 1 0
    MMRN1 Genopedia 1 0
    ZNF292 Genopedia 1 0
    PDXDC1 Genopedia 1 0
    PDS5B Genopedia 1 0
    SETD1B Genopedia 1 0
    FOXO1 Genopedia 1 0
    ZC3H13 Genopedia 1 0
    AKR1B1 Genopedia 1 0
    CRTC1 Genopedia 1 0
    ADNP Genopedia 1 0
    SIRT1 Genopedia 1 0
    TARDBP Genopedia 1 0
    SMUG1 Genopedia 1 0
    FRA6E Genopedia 1 0
    Egfr Genopedia 1 0
    Kras Genopedia 1 0
    MTOR Genopedia 1 0
    Tp53 Genopedia 1 0
    ABL1 Genopedia 1 0
    Cdkn2a Genopedia 1 0
    FUS Genopedia 1 0
    NEIL2 Genopedia 1 0
    tor Genopedia 1 0
    OR9Q2 Genopedia 1 0
    ALKBH3 Genopedia 1 0
    ESR2 Genopedia 1 0
    MECOM Genopedia 1 0
    ALCAM Genopedia 1 0
    FGFR1 Genopedia 1 0
    FGFR3 Genopedia 1 0
    MORC2 Genopedia 1 0
    FANCA Genopedia 1 0
    AGTR1 Genopedia 1 0
    DUT Genopedia 1 0
    Pik3ca Genopedia 1 0
    AGXT Genopedia 1 0
    AHCY Genopedia 1 0
    EEF1A1 Genopedia 1 0
    CYP2A6 Genopedia 1 0
    VPS37D Genopedia 1 0
    CYP2C19 Genopedia 1 0
    CYP2C9 Genopedia 1 0
    CYP2C18 Genopedia 1 0
    NQO1 Genopedia 1 0
    DKC1 Genopedia 1 0
    DMPK Genopedia 1 0
    DMRT1 Genopedia 1 0
    DNMT1 Genopedia 1 0
    DNMT3A Genopedia 1 0
    DNMT3B Genopedia 1 0
    ATN1 Genopedia 1 0
    ERBB3 Genopedia 1 0
    ERCC4 Genopedia 1 0
    EPHB2 Genopedia 1 0
    SLC36A1 Genopedia 1 0
    CYP1A2 Genopedia 1 0
    ARID2 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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