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HuGE Navigator|Phenopedia|PHGKB

Phenopedia


Drug Toxicity

288 genes has been reported with Drug Toxicity
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Associated Gene
Total Publication
Meta-analysis Publication
    HLA-B Genopedia 56 6
    HLA-A Genopedia 27 1
    MTHFR Genopedia 13 0
    HLA-C Genopedia 12 0
    CYP2C19 Genopedia 12 0
    CYP2C9 Genopedia 12 0
    TPMT Genopedia 12 1
    TNF Genopedia 11 0
    HLA-DRB1 Genopedia 10 0
    DPYD Genopedia 9 0
    CYP3A5 Genopedia 8 0
    EGFR Genopedia 8 0
    GSTM1 Genopedia 8 0
    TYMS Genopedia 8 0
    ABCB1 Genopedia 8 0
    CYP3A4 Genopedia 7 0
    UGT1A1 Genopedia 7 0
    CYP2B6 Genopedia 6 0
    GSTT1 Genopedia 6 0
    CDA Genopedia 5 0
    NAT2 Genopedia 5 0
    CYP2D6 Genopedia 5 0
    KRAS Genopedia 4 0
    VDR Genopedia 4 0
    ITPA Genopedia 4 0
    CTLA4 Genopedia 4 0
    DCK Genopedia 4 0
    ABCC2 Genopedia 4 0
    TLR3 Genopedia 3 0
    IL13 Genopedia 3 0
    SLC29A1 Genopedia 3 0
    HLA-DQB1 Genopedia 3 0
    DCTD Genopedia 3 0
    CYP1A2 Genopedia 3 0
    ERCC2 Genopedia 3 0
    IL4R Genopedia 3 0
    ADRB2 Genopedia 3 0
    GSTP1 Genopedia 3 0
    UGT1A7 Genopedia 3 0
    XRCC1 Genopedia 2 0
    KDR Genopedia 2 1
    RRM1 Genopedia 2 0
    AKT1 Genopedia 2 0
    VEGFA Genopedia 2 1
    LTA Genopedia 2 0
    SLC22A1 Genopedia 2 0
    ABCC1 Genopedia 2 0
    UGT1A9 Genopedia 2 0
    DPYS Genopedia 2 0
    GSTA1 Genopedia 2 0
    CCR2 Genopedia 2 0
    ACE Genopedia 2 0
    HLA-DQA1 Genopedia 2 0
    APOE Genopedia 2 0
    SLCO1B1 Genopedia 2 0
    NOD2 Genopedia 2 0
    ABCC4 Genopedia 2 0
    ABCA1 Genopedia 2 1
    SLC28A1 Genopedia 2 0
    SLC6A4 Genopedia 2 0
    INS Genopedia 2 0
    CCR5 Genopedia 2 0
    SELE Genopedia 2 0
    SLC28A3 Genopedia 2 0
    PNPLA3 Genopedia 1 0
    SLC12A8 Genopedia 1 0
    CCKBR Genopedia 1 0
    CD14 Genopedia 1 0
    CD28 Genopedia 1 0
    SCARB2 Genopedia 1 0
    CXCL5 Genopedia 1 0
    PRDM1 Genopedia 1 0
    APOA4 Genopedia 1 0
    IL1B Genopedia 1 0
    MDH1 Genopedia 1 0
    ATM Genopedia 1 1
    PIK3CA Genopedia 1 0
    PKLR Genopedia 1 0
    PON1 Genopedia 1 0
    HCP5 Genopedia 1 0
    PACSIN2 Genopedia 1 0
    CYP2A6 Genopedia 1 0
    ERCC1 Genopedia 1 0
    F5 Genopedia 1 0
    FABP4 Genopedia 1 0
    FGF1 Genopedia 1 1
    TBL2 Genopedia 1 0
    HINT1 Genopedia 1 0
    HLA-DPB1 Genopedia 1 0
    HRH3 Genopedia 1 0
    C3 Genopedia 1 0
    XRCC3 Genopedia 1 0
    APOBEC3B Genopedia 1 0
    ADORA2B Genopedia 1 0
    FGF4 Genopedia 1 1
    ABO Genopedia 1 0
    IL1A Genopedia 1 0
    IMPDH2 Genopedia 1 0
    MAOA Genopedia 1 0
    MMP2 Genopedia 1 0
    TM6SF2 Genopedia 1 0
    PRKAG3 Genopedia 1 0
    CCHCR1 Genopedia 1 0
    FBXL19 Genopedia 1 0
    PPARA Genopedia 1 0
    PRKAB2 Genopedia 1 0
    PTGER4 Genopedia 1 0
    WDFY4 Genopedia 1 0
    CARD15 Genopedia 1 0
    SLC19A1 Genopedia 1 0
    ABCC8 Genopedia 1 0
    TEK Genopedia 1 0
    TLR2 Genopedia 1 0
    COMT Genopedia 1 0
    CPT2 Genopedia 1 0
    ADRA1A Genopedia 1 0
    IL23R Genopedia 1 0
    ADRA2B Genopedia 1 0
    ADRB3 Genopedia 1 0
    INSR Genopedia 1 0
    IRS1 Genopedia 1 0
    LPL Genopedia 1 0
    MBL2 Genopedia 1 0
    PCK1 Genopedia 1 0
    ADIPOR1 Genopedia 1 0
    PSORS1C1 Genopedia 1 0
    ALDH1A1 Genopedia 1 0
    GYS1 Genopedia 1 0
    APEX1 Genopedia 1 0
    ICAM1 Genopedia 1 0
    FASLG Genopedia 1 0
    IL6 Genopedia 1 0
    PIK3CD Genopedia 1 0
    PRKAA1 Genopedia 1 0
    DTWD1 Genopedia 1 0
    AVEN Genopedia 1 0
    RARG Genopedia 1 0
    NFKBIZ Genopedia 1 0
    SREBF1 Genopedia 1 0
    ADIPOR2 Genopedia 1 0
    SLC28A2 Genopedia 1 0
    LIPG Genopedia 1 0
    CD40 Genopedia 1 0
    SOCS5 Genopedia 1 0
    USP15 Genopedia 1 0
    LEPR Genopedia 1 0
    CYP4F3 Genopedia 1 0
    MC3R Genopedia 1 0
    MMP12 Genopedia 1 0
    NOS3 Genopedia 1 0
    OLR1 Genopedia 1 0
    PFKM Genopedia 1 0
    PIK3C2B Genopedia 1 0
    UGT1A6 Genopedia 1 0
    SLC6A20 Genopedia 1 0
    RETN Genopedia 1 0
    RARB Genopedia 1 0
    CCL2 Genopedia 1 0
    CCL5 Genopedia 1 0
    AGXT2 Genopedia 1 0
    TSHR Genopedia 1 0
    UCP2 Genopedia 1 0
    PPP1R3B Genopedia 1 0
    CCK Genopedia 1 0
    TRAF3IP2 Genopedia 1 0
    SLC7A9 Genopedia 1 0
    CYP2E1 Genopedia 1 0
    DRD3 Genopedia 1 0
    HIF1A Genopedia 1 0
    ACACB Genopedia 1 0
    APOC3 Genopedia 1 0
    IL18 Genopedia 1 0
    TIMP3 Genopedia 1 0
    VKORC1 Genopedia 1 0
    COL18A1 Genopedia 1 1
    NRP1 Genopedia 1 1
    ABCG2 Genopedia 1 0
    NPY Genopedia 1 0
    PRKAG2 Genopedia 1 0
    GHRL Genopedia 1 0
    PFKFB1 Genopedia 1 0
    PFKL Genopedia 1 0
    PIK3C3 Genopedia 1 0
    PIK3CG Genopedia 1 0
    PPARG Genopedia 1 0
    PRKAB1 Genopedia 1 0
    BCHE Genopedia 1 0
    CHL1 Genopedia 1 0
    CPT1B Genopedia 1 0
    CRHR1 Genopedia 1 0
    CSF2 Genopedia 1 0
    CYP7A1 Genopedia 1 0
    AKT2 Genopedia 1 0
    F7 Genopedia 1 0
    GCG Genopedia 1 0
    ANGPT2 Genopedia 1 0
    CXCR1 Genopedia 1 0
    ACAT1 Genopedia 1 0
    LCAT Genopedia 1 0
    MC4R Genopedia 1 0
    IGF1 Genopedia 1 0
    TXNRD2 Genopedia 1 0
    HSPA1A Genopedia 1 0
    APOH Genopedia 1 0
    LIPA Genopedia 1 0
    LIPE Genopedia 1 0
    PIK3C2G Genopedia 1 0
    CMAS Genopedia 1 0
    PYGL Genopedia 1 0
    TGFA Genopedia 1 0
    UCP3 Genopedia 1 0
    VCAM1 Genopedia 1 0
    SLC22A16 Genopedia 1 0
    CD86 Genopedia 1 0
    CD40LG Genopedia 1 0
    NQO1 Genopedia 1 0
    GYS2 Genopedia 1 0
    EPHX1 Genopedia 1 0
    F2 Genopedia 1 0
    FGF2 Genopedia 1 1
    ADH6 Genopedia 1 0
    ADORA2A Genopedia 1 0
    CPT1A Genopedia 1 0
    NCAN Genopedia 1 0
    ADRA2A Genopedia 1 0
    CYP2C8 Genopedia 1 0
    CYP4B1 Genopedia 1 0
    CETP Genopedia 1 0
    CHKB Genopedia 1 0
    ERBB2 Genopedia 1 0
    ALDH3A1 Genopedia 1 0
    SACM1L Genopedia 1 0
    IL28B Genopedia 1 0
    NR3C1 Genopedia 1 0
    GSK3B Genopedia 1 0
    ACAT2 Genopedia 1 0
    COL12A1 Genopedia 1 0
    ADORA1 Genopedia 1 0
    IFNG Genopedia 1 0
    IL4 Genopedia 1 0
    IL10 Genopedia 1 0
    ITGB3 Genopedia 1 0
    PRKAA2 Genopedia 1 0
    PRKAG1 Genopedia 1 0
    PRKY Genopedia 1 0
    RARA Genopedia 1 0
    RFC1 Genopedia 1 0
    MYH7 Genopedia 1 0
    PFKP Genopedia 1 0
    PIK3CB Genopedia 1 0
    PIK3R1 Genopedia 1 0
    PKM2 Genopedia 1 0
    TLR9 Genopedia 1 0
    SCGB1A1 Genopedia 1 0
    MIF Genopedia 1 0
    MMP9 Genopedia 1 0
    DDX39B Genopedia 1 0
    CCKAR Genopedia 1 0
    GABRG2 Genopedia 1 0
    GHRH Genopedia 1 0
    ANGPT1 Genopedia 1 0
    CHRM3 Genopedia 1 0
    CRH Genopedia 1 0
    CRHR2 Genopedia 1 0
    ADORA3 Genopedia 1 0
    ADRB1 Genopedia 1 0
    CYBA Genopedia 1 0
    HBB Genopedia 1 0
    ACACA Genopedia 1 0
    CYP27B1 Genopedia 1 0
    ITGAL Genopedia 1 0
    HMGCR Genopedia 1 0
    HSPA1L Genopedia 1 0
    ABCG5 Genopedia 1 0
    SOD2 Genopedia 1 0
    TAP1 Genopedia 1 0
    TGFB1 Genopedia 1 0
    TIMP2 Genopedia 1 0
    C5 Genopedia 1 0
    LIPC Genopedia 1 0
    MTTP Genopedia 1 0
    NOS2 Genopedia 1 0
    CD207 Genopedia 1 0
    POMC Genopedia 1 0
    LIPF Genopedia 1 0
    CHST1 Genopedia 1 0
    MAGI2 Genopedia 1 0
    UGT1A3 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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