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HuGE Navigator|Phenopedia|PHGKB

Phenopedia


Drug Toxicity

294 genes has been reported with Drug Toxicity
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Associated Gene
Total Publication
Meta-analysis Publication
    HLA-B Genopedia 57 6
    HLA-A Genopedia 28 1
    MTHFR Genopedia 14 0
    TPMT Genopedia 12 1
    HLA-C Genopedia 12 0
    CYP2C19 Genopedia 12 0
    CYP2C9 Genopedia 12 0
    TNF Genopedia 11 0
    HLA-DRB1 Genopedia 10 0
    DPYD Genopedia 10 0
    ABCB1 Genopedia 9 0
    UGT1A1 Genopedia 8 0
    TYMS Genopedia 8 0
    EGFR Genopedia 8 0
    GSTM1 Genopedia 8 0
    CYP3A5 Genopedia 8 0
    CYP3A4 Genopedia 7 0
    CYP2B6 Genopedia 6 0
    GSTT1 Genopedia 6 0
    GSTP1 Genopedia 5 0
    CYP2D6 Genopedia 5 0
    ABCC2 Genopedia 5 0
    NAT2 Genopedia 5 0
    CDA Genopedia 5 0
    VDR Genopedia 4 0
    ITPA Genopedia 4 0
    CTLA4 Genopedia 4 0
    DCK Genopedia 4 0
    KRAS Genopedia 4 0
    IL4R Genopedia 3 0
    HLA-DQB1 Genopedia 3 0
    IL13 Genopedia 3 0
    SLC29A1 Genopedia 3 0
    DCTD Genopedia 3 0
    ADRB2 Genopedia 3 0
    CYP1A2 Genopedia 3 0
    ERCC2 Genopedia 3 0
    UGT1A7 Genopedia 3 0
    VEGFA Genopedia 3 1
    XRCC1 Genopedia 3 0
    TLR3 Genopedia 3 0
    ABCC1 Genopedia 2 0
    SLC6A4 Genopedia 2 0
    SLC22A1 Genopedia 2 0
    SLC28A1 Genopedia 2 0
    KDR Genopedia 2 1
    RRM1 Genopedia 2 0
    UGT1A9 Genopedia 2 0
    SELE Genopedia 2 0
    SLC28A3 Genopedia 2 0
    NOD2 Genopedia 2 0
    AKT1 Genopedia 2 0
    ACE Genopedia 2 0
    ABCC4 Genopedia 2 0
    CCR2 Genopedia 2 0
    CCR5 Genopedia 2 0
    SLCO1B1 Genopedia 2 0
    DPYS Genopedia 2 0
    ABCA1 Genopedia 2 1
    GSTA1 Genopedia 2 0
    HLA-DQA1 Genopedia 2 0
    CFH Genopedia 2 0
    IL10 Genopedia 2 0
    INS Genopedia 2 0
    APOE Genopedia 2 0
    LTA Genopedia 2 0
    CYP4F3 Genopedia 1 0
    MAOA Genopedia 1 0
    MBL2 Genopedia 1 0
    MC3R Genopedia 1 0
    MC4R Genopedia 1 0
    MDH1 Genopedia 1 0
    MIF Genopedia 1 0
    MMP2 Genopedia 1 0
    MMP9 Genopedia 1 0
    MMP12 Genopedia 1 0
    ACAT2 Genopedia 1 0
    LCAT Genopedia 1 0
    LEPR Genopedia 1 0
    LIPA Genopedia 1 0
    LIPC Genopedia 1 0
    LIPE Genopedia 1 0
    LPL Genopedia 1 0
    APOH Genopedia 1 0
    IL1A Genopedia 1 0
    IL1B Genopedia 1 0
    IL2 Genopedia 1 0
    FASLG Genopedia 1 0
    IL4 Genopedia 1 0
    IL6 Genopedia 1 0
    IL8 Genopedia 1 0
    CXCR1 Genopedia 1 0
    INSR Genopedia 1 0
    IRS1 Genopedia 1 0
    ITGAL Genopedia 1 0
    ITGB3 Genopedia 1 0
    IL18 Genopedia 1 0
    IMPDH2 Genopedia 1 0
    HIF1A Genopedia 1 0
    HINT1 Genopedia 1 0
    ACACA Genopedia 1 0
    HLA-DPB1 Genopedia 1 0
    HMGCR Genopedia 1 0
    ACACB Genopedia 1 0
    APEX1 Genopedia 1 0
    HSPA1A Genopedia 1 0
    HSPA1L Genopedia 1 0
    APOA4 Genopedia 1 0
    ICAM1 Genopedia 1 0
    APOC3 Genopedia 1 0
    IFNG Genopedia 1 0
    IGF1 Genopedia 1 0
    GYS1 Genopedia 1 0
    GYS2 Genopedia 1 0
    HBB Genopedia 1 0
    DRD3 Genopedia 1 0
    EPHX1 Genopedia 1 0
    ERBB2 Genopedia 1 0
    ERCC1 Genopedia 1 0
    CETP Genopedia 1 0
    CHL1 Genopedia 1 0
    TRAF3IP2 Genopedia 1 0
    HCP5 Genopedia 1 0
    CFHR4 Genopedia 1 0
    SLC7A9 Genopedia 1 0
    CHKB Genopedia 1 0
    PACSIN2 Genopedia 1 0
    HRH3 Genopedia 1 0
    CHRM3 Genopedia 1 0
    TXNRD2 Genopedia 1 0
    ADRA2A Genopedia 1 0
    ADRA2B Genopedia 1 0
    ADRB1 Genopedia 1 0
    CYBA Genopedia 1 0
    ADH6 Genopedia 1 0
    COL12A1 Genopedia 1 0
    COMT Genopedia 1 0
    ADORA1 Genopedia 1 0
    ADORA2A Genopedia 1 0
    ADORA2B Genopedia 1 0
    CPT1A Genopedia 1 0
    CPT1B Genopedia 1 0
    CPT2 Genopedia 1 0
    CRH Genopedia 1 0
    CRHR1 Genopedia 1 0
    CRHR2 Genopedia 1 0
    ADORA3 Genopedia 1 0
    CSF2 Genopedia 1 0
    NCAN Genopedia 1 0
    ADRA1A Genopedia 1 0
    IL23R Genopedia 1 0
    PSORS1C1 Genopedia 1 0
    NQO1 Genopedia 1 0
    CYP4B1 Genopedia 1 0
    CYP7A1 Genopedia 1 0
    CYP27B1 Genopedia 1 0
    CYP2A6 Genopedia 1 0
    ADRB3 Genopedia 1 0
    CYP1A1 Genopedia 1 0
    CYP2E1 Genopedia 1 0
    CYP2C8 Genopedia 1 0
    AKT2 Genopedia 1 0
    F2 Genopedia 1 0
    F5 Genopedia 1 0
    F7 Genopedia 1 0
    ALDH1A1 Genopedia 1 0
    FABP4 Genopedia 1 0
    ALDH3A1 Genopedia 1 0
    FGF1 Genopedia 1 1
    FGF2 Genopedia 1 1
    FGF4 Genopedia 1 1
    SACM1L Genopedia 1 0
    GABRG2 Genopedia 1 0
    GCG Genopedia 1 0
    TBL2 Genopedia 1 0
    GHRH Genopedia 1 0
    ABO Genopedia 1 0
    IL28B Genopedia 1 0
    ANGPT1 Genopedia 1 0
    ANGPT2 Genopedia 1 0
    NR3C1 Genopedia 1 0
    GSK3B Genopedia 1 0
    ABCG5 Genopedia 1 0
    NFKBIZ Genopedia 1 0
    AGXT2 Genopedia 1 0
    CARD15 Genopedia 1 0
    FBXL19 Genopedia 1 0
    PPARA Genopedia 1 0
    CCL2 Genopedia 1 0
    CCL5 Genopedia 1 0
    CXCL5 Genopedia 1 0
    PRDM1 Genopedia 1 0
    ACAT1 Genopedia 1 0
    UGT1A6 Genopedia 1 0
    UGT1A3 Genopedia 1 0
    PPARG Genopedia 1 0
    SLC6A20 Genopedia 1 0
    PRKAA1 Genopedia 1 0
    PRKAA2 Genopedia 1 0
    PRKAB1 Genopedia 1 0
    PRKAB2 Genopedia 1 0
    PRKAG1 Genopedia 1 0
    CEP72 Genopedia 1 0
    CMAS Genopedia 1 0
    PRKY Genopedia 1 0
    RETN Genopedia 1 0
    DTWD1 Genopedia 1 0
    AVEN Genopedia 1 0
    PTGER4 Genopedia 1 0
    WDFY4 Genopedia 1 0
    PYGL Genopedia 1 0
    BCHE Genopedia 1 0
    RARA Genopedia 1 0
    RARB Genopedia 1 0
    RARG Genopedia 1 0
    RFC1 Genopedia 1 0
    PIK3C2B Genopedia 1 0
    PIK3C2G Genopedia 1 0
    PIK3C3 Genopedia 1 0
    PIK3CA Genopedia 1 0
    PIK3CB Genopedia 1 0
    PIK3CD Genopedia 1 0
    PIK3CG Genopedia 1 0
    PIK3R1 Genopedia 1 0
    PKLR Genopedia 1 0
    PKM2 Genopedia 1 0
    TM6SF2 Genopedia 1 0
    PRKAG3 Genopedia 1 0
    TLR9 Genopedia 1 0
    POMC Genopedia 1 0
    PON1 Genopedia 1 0
    CCHCR1 Genopedia 1 0
    MTTP Genopedia 1 0
    MYH7 Genopedia 1 0
    ATM Genopedia 1 1
    NOS2 Genopedia 1 0
    NOS3 Genopedia 1 0
    NPY Genopedia 1 0
    OLR1 Genopedia 1 0
    CD207 Genopedia 1 0
    PCK1 Genopedia 1 0
    ADIPOR1 Genopedia 1 0
    PRKAG2 Genopedia 1 0
    GHRL Genopedia 1 0
    PFKFB1 Genopedia 1 0
    PFKL Genopedia 1 0
    PFKM Genopedia 1 0
    PFKP Genopedia 1 0
    CD14 Genopedia 1 0
    LIPG Genopedia 1 0
    CD28 Genopedia 1 0
    CD86 Genopedia 1 0
    ABCG2 Genopedia 1 0
    SCARB2 Genopedia 1 0
    CD40 Genopedia 1 0
    APOBEC3B Genopedia 1 0
    CD40LG Genopedia 1 0
    SOCS5 Genopedia 1 0
    MAGI2 Genopedia 1 0
    USP15 Genopedia 1 0
    UCP2 Genopedia 1 0
    UCP3 Genopedia 1 0
    SCGB1A1 Genopedia 1 0
    VCAM1 Genopedia 1 0
    SOD2 Genopedia 1 0
    SREBF1 Genopedia 1 0
    ABCC8 Genopedia 1 0
    TAP1 Genopedia 1 0
    TEK Genopedia 1 0
    TGFA Genopedia 1 0
    TGFB1 Genopedia 1 0
    TIMP2 Genopedia 1 0
    TIMP3 Genopedia 1 0
    TLR2 Genopedia 1 0
    SLC19A1 Genopedia 1 0
    C3 Genopedia 1 0
    TSHR Genopedia 1 0
    C5 Genopedia 1 0
    XRCC3 Genopedia 1 0
    VKORC1 Genopedia 1 0
    DDX39B Genopedia 1 0
    ADIPOR2 Genopedia 1 0
    PPP1R3B Genopedia 1 0
    PNPLA3 Genopedia 1 0
    COL18A1 Genopedia 1 1
    SLC12A8 Genopedia 1 0
    LIPF Genopedia 1 0
    CHST1 Genopedia 1 0
    SLC22A16 Genopedia 1 0
    NRP1 Genopedia 1 1
    CCK Genopedia 1 0
    CCKAR Genopedia 1 0
    CCKBR Genopedia 1 0
    SLC28A2 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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