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Phenopedia


Depressive Disorder, Major
576 genes has been reported with Depressive Disorder, Major
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Associated Gene
Total Publication
Meta-analysis Publication
    SLC6A4 Genopedia 216 6
    BDNF Genopedia 111 6
    COMT Genopedia 61 3
    HTR2A Genopedia 59 8
    HTR1A Genopedia 49 3
    TPH2 Genopedia 34 2
    TPH1 Genopedia 34 6
    SLC6A2 Genopedia 33 4
    MAOA Genopedia 28 3
    CYP2D6 Genopedia 25 0
    NR3C1 Genopedia 23 0
    FKBP5 Genopedia 23 2
    ABCB1 Genopedia 22 2
    APOE Genopedia 21 1
    GNB3 Genopedia 19 3
    CRHR1 Genopedia 19 1
    CREB1 Genopedia 17 1
    MTHFR Genopedia 16 1
    CACNA1C Genopedia 15 4
    DRD2 Genopedia 14 0
    GSK3B Genopedia 14 0
    ACE Genopedia 14 1
    CYP2C19 Genopedia 13 0
    SLC6A3 Genopedia 13 1
    PCLO Genopedia 11 1
    CLOCK Genopedia 10 1
    HTR1B Genopedia 10 0
    MDD1 Genopedia 9 0
    DRD3 Genopedia 9 1
    NTRK2 Genopedia 9 0
    DRD4 Genopedia 9 0
    TNF Genopedia 8 0
    GRM7 Genopedia 8 2
    IL1B Genopedia 8 1
    DISC1 Genopedia 7 0
    VEGFA Genopedia 7 0
    NRG1 Genopedia 7 1
    HTR6 Genopedia 6 2
    IL6 Genopedia 6 0
    CYP2C9 Genopedia 6 0
    P2RX7 Genopedia 6 0
    AGTR1 Genopedia 6 0
    DTNBP1 Genopedia 6 0
    CYP1A2 Genopedia 6 0
    HTR2C Genopedia 6 0
    CRY2 Genopedia 5 0
    FTO Genopedia 5 2
    HTT Genopedia 5 0
    DAOA Genopedia 5 0
    ANK3 Genopedia 5 2
    ADRA2A Genopedia 5 0
    GRIK4 Genopedia 5 0
    CNR1 Genopedia 5 0
    IL10 Genopedia 5 0
    GRIA4 Genopedia 4 0
    CRHR2 Genopedia 4 0
    ESR1 Genopedia 4 0
    HTR3A Genopedia 4 1
    DBH Genopedia 4 0
    DRD1 Genopedia 4 0
    SLC6A15 Genopedia 4 1
    OPRM1 Genopedia 4 0
    BICC1 Genopedia 4 1
    OXTR Genopedia 4 0
    AVPR1B Genopedia 4 0
    NGFR Genopedia 4 0
    IFNG Genopedia 4 0
    GABRA6 Genopedia 3 0
    GAL Genopedia 3 1
    LSAMP Genopedia 3 0
    GRN Genopedia 3 1
    CRH Genopedia 3 0
    CRY1 Genopedia 3 0
    EGF Genopedia 3 0
    CRP Genopedia 3 1
    GPR50 Genopedia 3 0
    ESR2 Genopedia 3 0
    AR Genopedia 3 0
    EHD3 Genopedia 3 0
    HTR3B Genopedia 3 1
    CACNB2 Genopedia 3 1
    IL11 Genopedia 3 0
    RORA Genopedia 3 0
    NCAM1 Genopedia 3 0
    CRHBP Genopedia 3 0
    ZNF804A Genopedia 3 1
    PER2 Genopedia 3 0
    CCL2 Genopedia 3 0
    PTPRR Genopedia 3 0
    TSNAX Genopedia 3 0
    ADSL Genopedia 3 1
    POMC Genopedia 3 0
    IL2 Genopedia 3 0
    NR3C2 Genopedia 3 0
    PER3 Genopedia 3 0
    PPP1R1B Genopedia 2 0
    CCKAR Genopedia 2 0
    TERT Genopedia 2 0
    CSMD1 Genopedia 2 1
    NR1D1 Genopedia 2 0
    GRIA2 Genopedia 2 0
    CTNNA3 Genopedia 2 1
    LEP Genopedia 2 0
    MAPT Genopedia 2 1
    FAAH Genopedia 2 0
    CHRM2 Genopedia 2 0
    ADCY9 Genopedia 2 0
    AKT1 Genopedia 2 0
    S100B Genopedia 2 0
    GABRG2 Genopedia 2 0
    NPAS2 Genopedia 2 0
    AVP Genopedia 2 0
    TP53 Genopedia 2 0
    HOMER1 Genopedia 2 0
    NOS3 Genopedia 2 0
    NPY Genopedia 2 0
    NOVA2 Genopedia 2 0
    CTLA4 Genopedia 2 0
    CNR2 Genopedia 2 0
    AGT Genopedia 2 0
    BCL2 Genopedia 2 0
    NCAN Genopedia 2 0
    PPARGC1A Genopedia 2 0
    UCN3 Genopedia 2 0
    FGF2 Genopedia 2 0
    GABRA3 Genopedia 2 0
    PER1 Genopedia 2 0
    SAT1 Genopedia 2 0
    ITIH3 Genopedia 2 1
    HSPA1A Genopedia 2 0
    PRKCG Genopedia 2 0
    SYNE1 Genopedia 2 2
    LOC100506013 Genopedia 2 0
    TGFB1 Genopedia 2 0
    SNAP25 Genopedia 2 0
    ARNTL Genopedia 2 0
    PGP Genopedia 2 1
    GRIA1 Genopedia 2 0
    GRIA3 Genopedia 2 0
    FADS1 Genopedia 2 0
    PDE9A Genopedia 2 0
    DIO2 Genopedia 2 0
    NLGN1 Genopedia 2 1
    YWHAE Genopedia 2 0
    GNAS Genopedia 2 0
    IDO2 Genopedia 2 0
    IL19 Genopedia 2 0
    ITIH4 Genopedia 2 0
    FGFR2 Genopedia 2 0
    ADCYAP1 Genopedia 2 0
    LHPP Genopedia 2 0
    PDE11A Genopedia 2 0
    DIO1 Genopedia 2 0
    ELK3 Genopedia 2 1
    C5orf20 Genopedia 2 1
    SP4 Genopedia 2 0
    NOS1 Genopedia 2 0
    PPIG Genopedia 2 0
    ZEB2 Genopedia 2 0
    TH Genopedia 2 0
    ADRA2C Genopedia 2 0
    CHL1 Genopedia 2 0
    GAD1 Genopedia 2 0
    PSMD9 Genopedia 2 0
    GRIK3 Genopedia 2 1
    BCR Genopedia 2 0
    SLC18A1 Genopedia 2 0
    ADRB1 Genopedia 2 0
    HSPA1L Genopedia 2 0
    MAPK1 Genopedia 2 0
    MAP2K1 Genopedia 2 0
    HTR5A Genopedia 2 0
    ANPEP Genopedia 2 0
    ADCY3 Genopedia 2 1
    ADM Genopedia 2 0
    KCNK2 Genopedia 2 0
    C7orf49 Genopedia 2 0
    IKBKE Genopedia 2 0
    SDPR Genopedia 1 0
    TOX2 Genopedia 1 0
    EIF2B2 Genopedia 1 0
    MAGI1 Genopedia 1 0
    NRXN3 Genopedia 1 0
    ABCG1 Genopedia 1 0
    OR7E26P Genopedia 1 1
    ACCN2 Genopedia 1 0
    MMP8 Genopedia 1 0
    ADORA1 Genopedia 1 0
    TMEM161B Genopedia 1 0
    ABCA13 Genopedia 1 0
    C10orf32 Genopedia 1 0
    ADK Genopedia 1 0
    TSNAX-DISC1 Genopedia 1 0
    ABCB6 Genopedia 1 0
    ST3GAL6 Genopedia 1 0
    SLC29A2 Genopedia 1 0
    GAP43 Genopedia 1 0
    GFRA1 Genopedia 1 0
    PCDH17 Genopedia 1 0
    CELF4 Genopedia 1 1
    RNR1 Genopedia 1 0
    RPS6KA2 Genopedia 1 0
    PRDM1 Genopedia 1 0
    USP46 Genopedia 1 0
    SORL1 Genopedia 1 1
    CYTB Genopedia 1 0
    UCN Genopedia 1 0
    WNT7A Genopedia 1 0
    GMIP Genopedia 1 0
    PDE1A Genopedia 1 0
    PGF Genopedia 1 0
    PLA2G4A Genopedia 1 0
    PON1 Genopedia 1 0
    ELP3 Genopedia 1 0
    MCTP2 Genopedia 1 0
    SKA2 Genopedia 1 0
    C15orf53 Genopedia 1 1
    NXPH1 Genopedia 1 0
    TSPAN5 Genopedia 1 1
    SIGMAR1 Genopedia 1 0
    ADCY2 Genopedia 1 0
    CPM Genopedia 1 0
    DGKH Genopedia 1 0
    MDGA2 Genopedia 1 0
    DPYD Genopedia 1 0
    FABP2 Genopedia 1 0
    GABRE Genopedia 1 0
    ZBTB20 Genopedia 1 0
    MIR182 Genopedia 1 0
    IL20 Genopedia 1 0
    SNTG2 Genopedia 1 0
    ARNTL2 Genopedia 1 0
    TBX20 Genopedia 1 0
    KIAA1244 Genopedia 1 0
    DLK2 Genopedia 1 0
    TCF7L2 Genopedia 1 0
    TCTA Genopedia 1 0
    CHRFAM7A Genopedia 1 0
    KALRN Genopedia 1 0
    MAGI2 Genopedia 1 0
    ND6 Genopedia 1 0
    TARBP2 Genopedia 1 0
    TGFBR2 Genopedia 1 0
    ZNF80 Genopedia 1 0
    ZNF385D Genopedia 1 0
    TNKS2 Genopedia 1 0
    AXIN2 Genopedia 1 0
    MAD1L1 Genopedia 1 0
    BHLHE40 Genopedia 1 0
    PDE5A Genopedia 1 0
    NTN1 Genopedia 1 0
    CD38 Genopedia 1 0
    DMTF1 Genopedia 1 1
    TOMM40 Genopedia 1 0
    NKPD1 Genopedia 1 1
    GZMK Genopedia 1 0
    ITGB1 Genopedia 1 0
    NRAS Genopedia 1 0
    NRGN Genopedia 1 1
    PSME2 Genopedia 1 0
    RP1 Genopedia 1 0
    AVPR1A Genopedia 1 0
    SLC16A2 Genopedia 1 0
    TIPRL Genopedia 1 1
    IL28RA Genopedia 1 0
    DVL3 Genopedia 1 0
    SLC29A1 Genopedia 1 0
    EFEMP1 Genopedia 1 0
    SMCHD1 Genopedia 1 0
    CRTC1 Genopedia 1 0
    ADCY5 Genopedia 1 0
    FOXN3 Genopedia 1 0
    ADCY8 Genopedia 1 0
    CYP2B6 Genopedia 1 0
    TSC2 Genopedia 1 0
    CACNA1A Genopedia 1 1
    CACNA1D Genopedia 1 0
    FAT4 Genopedia 1 1
    FZD3 Genopedia 1 0
    KCNIP4 Genopedia 1 0
    OR2G2 Genopedia 1 1
    TRPA1 Genopedia 1 0
    UCN2 Genopedia 1 0
    EGFR Genopedia 1 0
    PCNT Genopedia 1 0
    PDE2A Genopedia 1 0
    PLXNA2 Genopedia 1 0
    PARP14 Genopedia 1 0
    DTWD1 Genopedia 1 0
    RBM4 Genopedia 1 0
    SLC5A4 Genopedia 1 0
    BMP7 Genopedia 1 0
    SLIT3 Genopedia 1 0
    STAC Genopedia 1 0
    SULT2A1 Genopedia 1 0
    TERC Genopedia 1 0
    IGFBP3 Genopedia 1 0
    ARRB1 Genopedia 1 0
    NDUFV2 Genopedia 1 0
    CYP3A4 Genopedia 1 0
    ADORA2A Genopedia 1 0
    UST Genopedia 1 0
    CDH13 Genopedia 1 0
    HTR3D Genopedia 1 0
    ENPEP Genopedia 1 0
    GAD2 Genopedia 1 0
    GDNF Genopedia 1 0
    ZBTB32 Genopedia 1 0
    ZNF366 Genopedia 1 0
    NQO1 Genopedia 1 0
    PCDH9 Genopedia 1 1
    LEF1 Genopedia 1 0
    PDE4B Genopedia 1 0
    LGSN Genopedia 1 0
    ABCB4 Genopedia 1 0
    PRKCH Genopedia 1 0
    PRNP Genopedia 1 1
    PSMA7 Genopedia 1 0
    PSMB4 Genopedia 1 0
    SLC4A10 Genopedia 1 0
    PTGS2 Genopedia 1 0
    DPP10 Genopedia 1 0
    SLC7A4 Genopedia 1 0
    STK3 Genopedia 1 0
    NRP1 Genopedia 1 0
    PAPLN Genopedia 1 0
    SLC28A1 Genopedia 1 0
    CMYA5 Genopedia 1 0
    PABPC4L Genopedia 1 0
    CREM Genopedia 1 0
    CUX1 Genopedia 1 0
    DIO3 Genopedia 1 0
    ADCY1 Genopedia 1 0
    NRG3 Genopedia 1 0
    IL24 Genopedia 1 0
    ADCY7 Genopedia 1 0
    GABRA2 Genopedia 1 0
    GABRP Genopedia 1 0
    C11orf41 Genopedia 1 0
    TBX21 Genopedia 1 0
    IGF1 Genopedia 1 0
    MTRR Genopedia 1 0
    NDUFB2 Genopedia 1 0
    NT5E Genopedia 1 0
    MIR19A Genopedia 1 0
    ATXN3 Genopedia 1 0
    NFATC2 Genopedia 1 0
    NTSR1 Genopedia 1 0
    TMEM66 Genopedia 1 0
    ERBB4 Genopedia 1 0
    VPS33B Genopedia 1 0
    CDH17 Genopedia 1 0
    PDLIM5 Genopedia 1 0
    CPLX2 Genopedia 1 0
    VCAN Genopedia 1 0
    ADRA1A Genopedia 1 0
    DBP Genopedia 1 0
    PRICKLE2 Genopedia 1 0
    GRIK1 Genopedia 1 0
    PSEN1 Genopedia 1 0
    PSMD13 Genopedia 1 0
    SRR Genopedia 1 0
    BMP5 Genopedia 1 0
    STIM1 Genopedia 1 0
    SLC28A2 Genopedia 1 0
    HP Genopedia 1 0
    WFS1 Genopedia 1 1
    CNTNAP2 Genopedia 1 0
    ADA Genopedia 1 0
    CDH12 Genopedia 1 0
    PDE10A Genopedia 1 0
    AHCY Genopedia 1 0
    ADCY4 Genopedia 1 0
    EMX2 Genopedia 1 0
    FGF9 Genopedia 1 0
    DCC Genopedia 1 0
    FREM3 Genopedia 1 0
    ADAMTS16 Genopedia 1 0
    AFAP1L1 Genopedia 1 0
    PXDNL Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    AANAT Genopedia 1 0
    CSGALNACT1 Genopedia 1 0
    GABRQ Genopedia 1 0
    MLL5 Genopedia 1 0
    SLC17A7 Genopedia 1 0
    AKTIP Genopedia 1 0
    SLC6A1 Genopedia 1 0
    LTA Genopedia 1 0
    IGLV2-8 Genopedia 1 0
    IL4 Genopedia 1 0
    VSTM5 Genopedia 1 1
    L1CAM Genopedia 1 0
    NPY2R Genopedia 1 0
    ORM1 Genopedia 1 0
    SPR Genopedia 1 1
    ND4L Genopedia 1 0
    SYN2 Genopedia 1 0
    TLR4 Genopedia 1 0
    FXR1 Genopedia 1 0
    NLRP12 Genopedia 1 0
    TSPO Genopedia 1 0
    ST8SIA2 Genopedia 1 0
    PKP4 Genopedia 1 0
    SLC6A5 Genopedia 1 0
    CD3E Genopedia 1 0
    DLGAP1 Genopedia 1 0
    SV2B Genopedia 1 0
    TNFRSF1A Genopedia 1 0
    VIPR2 Genopedia 1 0
    XBP1 Genopedia 1 0
    TFCP2 Genopedia 1 0
    NUCKS1 Genopedia 1 0
    ADARB1 Genopedia 1 0
    CPLX1 Genopedia 1 0
    CHRNA7 Genopedia 1 0
    CNP Genopedia 1 0
    MACROD2 Genopedia 1 0
    CSNK1E Genopedia 1 0
    SLC35G1 Genopedia 1 1
    GRIP1 Genopedia 1 0
    GRIN2B Genopedia 1 0
    CFH Genopedia 1 1
    TAAR6 Genopedia 1 0
    DVL2 Genopedia 1 0
    AGTR2 Genopedia 1 0
    MYT1L Genopedia 1 0
    WDFY4 Genopedia 1 0
    PTPRD Genopedia 1 0
    RGS4 Genopedia 1 0
    RIT2 Genopedia 1 0
    RPS6KA1 Genopedia 1 0
    M6PR Genopedia 1 0
    MTNR1B Genopedia 1 0
    SERPINE1 Genopedia 1 0
    RHCG Genopedia 1 0
    ATP6V0A1 Genopedia 1 1
    IL6R Genopedia 1 0
    HPRTP4 Genopedia 1 1
    CDH7 Genopedia 1 1
    FASLG Genopedia 1 0
    ANKK1 Genopedia 1 0
    ARRB2 Genopedia 1 0
    IDO1 Genopedia 1 0
    ITIH1 Genopedia 1 0
    TNFRSF1B Genopedia 1 0
    TTR Genopedia 1 0
    REEP5 Genopedia 1 0
    C7orf23 Genopedia 1 1
    CADPS Genopedia 1 0
    TIMELESS Genopedia 1 0
    SLC2A9 Genopedia 1 0
    RGMA Genopedia 1 0
    HTR3E Genopedia 1 0
    GRM8 Genopedia 1 1
    APC Genopedia 1 0
    CDH10 Genopedia 1 0
    ADRB3 Genopedia 1 0
    OR4B1 Genopedia 1 0
    ELAVL1 Genopedia 1 0
    SLC29A4 Genopedia 1 0
    BCL9 Genopedia 1 0
    NT5C1B Genopedia 1 0
    ELAVL4 Genopedia 1 0
    PTK2B Genopedia 1 0
    TBC1D1 Genopedia 1 0
    LAT Genopedia 1 1
    DAOA-AS1 Genopedia 1 0
    GPX1 Genopedia 1 0
    GRIK2 Genopedia 1 0
    SLCO6A1 Genopedia 1 0
    SGCZ Genopedia 1 0
    CSF2RB Genopedia 1 0
    MIR1202 Genopedia 1 0
    ADAR Genopedia 1 0
    ADCY6 Genopedia 1 0
    PRKCDBP Genopedia 1 0
    ADCYAP1R1 Genopedia 1 0
    CYP27A1 Genopedia 1 0
    GRIN2A Genopedia 1 0
    HTR2B Genopedia 1 0
    INS Genopedia 1 0
    JARID2 Genopedia 1 0
    MC2R Genopedia 1 0
    PGC Genopedia 1 1
    SAGE1 Genopedia 1 0
    ATF7IP Genopedia 1 0
    MTNR1A Genopedia 1 0
    FOXP2 Genopedia 1 0
    APOO Genopedia 1 0
    BHLHE41 Genopedia 1 0
    ACSS3 Genopedia 1 0
    NR4A3 Genopedia 1 0
    S100A10 Genopedia 1 0
    VAMP2 Genopedia 1 0
    TAP2 Genopedia 1 0
    TCF4 Genopedia 1 0
    TEF Genopedia 1 0
    FIGN Genopedia 1 0
    FANCI Genopedia 1 0
    STK32B Genopedia 1 0
    PRODH Genopedia 1 0
    CCBL2 Genopedia 1 0
    OR1D2 Genopedia 1 1
    PAM Genopedia 1 0
    PDE6C Genopedia 1 0
    ACP1 Genopedia 1 0
    ITGA9 Genopedia 1 0
    MIR30E Genopedia 1 0
    MIR34B Genopedia 1 0
    MAOB Genopedia 1 0
    NOS2 Genopedia 1 0
    APAF1 Genopedia 1 0
    HTR1D Genopedia 1 0
    BRP44 Genopedia 1 1
    PRPF31 Genopedia 1 1
    GCH1 Genopedia 1 0
    GRM4 Genopedia 1 0
    ACSL4 Genopedia 1 0
    FGF14 Genopedia 1 0
    CLASP2 Genopedia 1 0
    Slc6a4 Genopedia 1 0
    DPP4 Genopedia 1 0
    EPHB1 Genopedia 1 0
    ADRB2 Genopedia 1 0
    CNTF Genopedia 1 0
    CREBBP Genopedia 1 0
    CDH9 Genopedia 1 0
    KLHL2 Genopedia 1 1
    ACSM1 Genopedia 1 0
    RGS18 Genopedia 1 0
    SOD2 Genopedia 1 0
    STAR Genopedia 1 0
    STAT3 Genopedia 1 0
    VCP Genopedia 1 0
    VIP Genopedia 1 0
    Crh Genopedia 1 0
    KMO Genopedia 1 0
    DLK1 Genopedia 1 0
    DDX21 Genopedia 1 0
    NDST3 Genopedia 1 0
    NRXN1 Genopedia 1 0
    FADS2 Genopedia 1 0
    UBE3C Genopedia 1 0
    GPRIN2 Genopedia 1 0
    CDC25B Genopedia 1 0
    GNB1L Genopedia 1 0
    TMEM132D Genopedia 1 0
    DEGS2 Genopedia 1 0
    CTNND2 Genopedia 1 0
    DDC Genopedia 1 1
    HTR3C Genopedia 1 0
    EMP1 Genopedia 1 0
    SACM1L Genopedia 1 0
    SIRT1 Genopedia 1 0
    MDGA1 Genopedia 1 0
    GRID2 Genopedia 1 0
    GPHN Genopedia 1 0
    SEC23IP Genopedia 1 0
    MEF2C Genopedia 1 0
    ITGB3 Genopedia 1 0
    GSTK1 Genopedia 1 0
    Htt Genopedia 1 0
    HSPA1B Genopedia 1 0
    ABCC1 Genopedia 1 0
    NTRK3 Genopedia 1 0
    PAWR Genopedia 1 0
    SLC29A3 Genopedia 1 0
    MAP2K7 Genopedia 1 0
    AS3MT Genopedia 1 0
    KIAA1549 Genopedia 1 0
    RFX3 Genopedia 1 1
    ROBO2 Genopedia 1 0
    OR10R1P Genopedia 1 0
    ND2 Genopedia 1 0
    LGI1 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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