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Phenopedia


Depressive Disorder, Major

557 genes has been reported with Depressive Disorder, Major
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Associated Gene
Total Publication
Meta-analysis Publication
    SLC6A4 Genopedia 208 6
    BDNF Genopedia 103 6
    COMT Genopedia 59 3
    HTR2A Genopedia 57 8
    HTR1A Genopedia 48 3
    TPH1 Genopedia 33 6
    TPH2 Genopedia 31 2
    SLC6A2 Genopedia 29 3
    MAOA Genopedia 28 3
    CYP2D6 Genopedia 23 0
    ABCB1 Genopedia 22 2
    FKBP5 Genopedia 21 2
    NR3C1 Genopedia 21 0
    APOE Genopedia 21 1
    GNB3 Genopedia 18 3
    CRHR1 Genopedia 18 1
    MTHFR Genopedia 16 1
    CREB1 Genopedia 16 0
    DRD2 Genopedia 14 0
    CACNA1C Genopedia 14 4
    ACE Genopedia 14 1
    GSK3B Genopedia 13 0
    CYP2C19 Genopedia 13 0
    SLC6A3 Genopedia 12 1
    PCLO Genopedia 11 1
    CLOCK Genopedia 9 1
    DRD4 Genopedia 9 0
    DRD3 Genopedia 9 1
    MDD1 Genopedia 9 0
    HTR1B Genopedia 9 0
    TNF Genopedia 8 0
    IL1B Genopedia 8 1
    NTRK2 Genopedia 8 0
    GRM7 Genopedia 7 2
    DISC1 Genopedia 7 0
    NRG1 Genopedia 7 1
    HTR6 Genopedia 6 2
    AGTR1 Genopedia 6 0
    CYP2C9 Genopedia 6 0
    DTNBP1 Genopedia 6 0
    P2RX7 Genopedia 6 0
    FTO Genopedia 5 2
    VEGFA Genopedia 5 0
    ANK3 Genopedia 5 2
    IL10 Genopedia 5 0
    GRIK4 Genopedia 5 0
    CRY2 Genopedia 5 0
    ADRA2A Genopedia 5 0
    CYP1A2 Genopedia 5 0
    HTR2C Genopedia 5 0
    IL6 Genopedia 5 0
    CNR1 Genopedia 5 0
    DAOA Genopedia 5 0
    HTT Genopedia 5 0
    DBH Genopedia 4 0
    SLC6A15 Genopedia 4 1
    BICC1 Genopedia 4 1
    OPRM1 Genopedia 4 0
    DRD1 Genopedia 4 0
    HTR3A Genopedia 4 1
    AVPR1B Genopedia 4 0
    GRIA4 Genopedia 4 0
    IFNG Genopedia 4 0
    NGFR Genopedia 4 0
    ESR1 Genopedia 4 0
    CRHR2 Genopedia 4 0
    CRH Genopedia 3 0
    IL11 Genopedia 3 0
    LSAMP Genopedia 3 0
    POMC Genopedia 3 0
    GAL Genopedia 3 1
    CACNB2 Genopedia 3 1
    GABRA6 Genopedia 3 0
    PER3 Genopedia 3 0
    PER2 Genopedia 3 0
    TSNAX Genopedia 3 0
    CRY1 Genopedia 3 0
    EGF Genopedia 3 0
    AR Genopedia 3 0
    OXTR Genopedia 3 0
    ESR2 Genopedia 3 0
    GPR50 Genopedia 3 0
    PTPRR Genopedia 3 0
    CCL2 Genopedia 3 0
    ZNF804A Genopedia 3 1
    HTR3B Genopedia 3 1
    NCAM1 Genopedia 3 0
    CRHBP Genopedia 3 0
    EHD3 Genopedia 3 0
    IL2 Genopedia 3 0
    ADSL Genopedia 3 1
    GRN Genopedia 3 1
    S100B Genopedia 2 0
    KCNK2 Genopedia 2 0
    ARNTL Genopedia 2 0
    MAPT Genopedia 2 1
    ADM Genopedia 2 0
    CHRM2 Genopedia 2 0
    DIO2 Genopedia 2 0
    NLGN1 Genopedia 2 1
    MAPK1 Genopedia 2 0
    MAP2K1 Genopedia 2 0
    ANPEP Genopedia 2 0
    IKBKE Genopedia 2 0
    IDO2 Genopedia 2 0
    IL19 Genopedia 2 0
    GNAS Genopedia 2 0
    GABRA3 Genopedia 2 0
    C5orf20 Genopedia 2 1
    PPARGC1A Genopedia 2 0
    UCN3 Genopedia 2 0
    ELK3 Genopedia 2 1
    BCL2 Genopedia 2 0
    SP4 Genopedia 2 0
    TH Genopedia 2 0
    LHPP Genopedia 2 0
    BCR Genopedia 2 0
    NOS3 Genopedia 2 0
    NOVA2 Genopedia 2 0
    FGFR2 Genopedia 2 0
    ADCYAP1 Genopedia 2 0
    GRIK3 Genopedia 2 1
    ITIH3 Genopedia 2 1
    ITIH4 Genopedia 2 0
    FGF2 Genopedia 2 0
    NOS1 Genopedia 2 0
    PER1 Genopedia 2 0
    CRP Genopedia 2 0
    DIO1 Genopedia 2 0
    NCAN Genopedia 2 0
    ZEB2 Genopedia 2 0
    HSPA1A Genopedia 2 0
    SAT1 Genopedia 2 0
    YWHAE Genopedia 2 0
    CTLA4 Genopedia 2 0
    ADRA2C Genopedia 2 0
    AGT Genopedia 2 0
    CNR2 Genopedia 2 0
    SLC18A1 Genopedia 2 0
    GAD1 Genopedia 2 0
    TP53 Genopedia 2 0
    NPY Genopedia 2 0
    PSMD9 Genopedia 2 0
    PDE11A Genopedia 2 0
    HTR5A Genopedia 2 0
    CCKAR Genopedia 2 0
    NR1D1 Genopedia 2 0
    PGP Genopedia 2 1
    GRIA1 Genopedia 2 0
    GRIA2 Genopedia 2 0
    GRIA3 Genopedia 2 0
    ADCY3 Genopedia 2 1
    ADCY9 Genopedia 2 0
    FAAH Genopedia 2 0
    C7orf49 Genopedia 2 0
    TERT Genopedia 2 0
    PPP1R1B Genopedia 2 0
    CSMD1 Genopedia 2 1
    SNAP25 Genopedia 2 0
    CTNNA3 Genopedia 2 1
    NR3C2 Genopedia 2 0
    PDE9A Genopedia 2 0
    HSPA1L Genopedia 2 0
    NPAS2 Genopedia 2 0
    PRKCG Genopedia 2 0
    AVP Genopedia 2 0
    AKT1 Genopedia 2 0
    SYNE1 Genopedia 2 2
    GABRG2 Genopedia 2 0
    TGFB1 Genopedia 2 0
    RORA Genopedia 2 0
    TNFRSF1A Genopedia 1 0
    VCP Genopedia 1 0
    VIP Genopedia 1 0
    VIPR2 Genopedia 1 0
    BRP44 Genopedia 1 1
    GCH1 Genopedia 1 0
    GRIP1 Genopedia 1 0
    GABRE Genopedia 1 0
    FGF14 Genopedia 1 0
    CLASP2 Genopedia 1 0
    ITGA9 Genopedia 1 0
    C15orf53 Genopedia 1 1
    HTR1D Genopedia 1 0
    SKA2 Genopedia 1 0
    GRM4 Genopedia 1 0
    NXPH1 Genopedia 1 0
    CFH Genopedia 1 1
    MACROD2 Genopedia 1 0
    ADRB1 Genopedia 1 0
    ADRB2 Genopedia 1 0
    SLC35G1 Genopedia 1 1
    DGKH Genopedia 1 0
    DPP4 Genopedia 1 0
    DPYD Genopedia 1 0
    AGTR2 Genopedia 1 0
    CDH9 Genopedia 1 0
    ADCY2 Genopedia 1 0
    CPLX1 Genopedia 1 0
    CHRNA7 Genopedia 1 0
    ACSM1 Genopedia 1 0
    CNP Genopedia 1 0
    CPM Genopedia 1 0
    CREBBP Genopedia 1 0
    FANCI Genopedia 1 0
    STK32B Genopedia 1 0
    RGS18 Genopedia 1 0
    NUCKS1 Genopedia 1 0
    DLK2 Genopedia 1 0
    SOD2 Genopedia 1 0
    STAR Genopedia 1 0
    STAT3 Genopedia 1 0
    Crh Genopedia 1 0
    KMO Genopedia 1 0
    CHRFAM7A Genopedia 1 0
    CD3E Genopedia 1 0
    DLGAP1 Genopedia 1 0
    NDST3 Genopedia 1 0
    NRXN1 Genopedia 1 0
    MAGI2 Genopedia 1 0
    SV2B Genopedia 1 0
    PRODH Genopedia 1 0
    KIAA1244 Genopedia 1 0
    PTPRD Genopedia 1 0
    RIT2 Genopedia 1 0
    GNB1L Genopedia 1 0
    MTNR1B Genopedia 1 0
    NOS2 Genopedia 1 0
    IL20 Genopedia 1 0
    PAM Genopedia 1 0
    ACP1 Genopedia 1 0
    ATP6V0A1 Genopedia 1 1
    SNTG2 Genopedia 1 0
    PLA2G4A Genopedia 1 0
    SLC29A3 Genopedia 1 0
    MCTP2 Genopedia 1 0
    GABRQ Genopedia 1 0
    MLL5 Genopedia 1 0
    CELF4 Genopedia 1 1
    AKTIP Genopedia 1 0
    ABCC1 Genopedia 1 0
    NPY2R Genopedia 1 0
    ORM1 Genopedia 1 0
    Htt Genopedia 1 0
    SPR Genopedia 1 1
    USP46 Genopedia 1 0
    GMIP Genopedia 1 0
    PDE1A Genopedia 1 0
    IL4 Genopedia 1 0
    TOX2 Genopedia 1 0
    UCN Genopedia 1 0
    FXR1 Genopedia 1 0
    SACM1L Genopedia 1 0
    SIRT1 Genopedia 1 0
    TMEM132D Genopedia 1 0
    DDC Genopedia 1 1
    ADCY4 Genopedia 1 0
    EMP1 Genopedia 1 0
    EMX2 Genopedia 1 0
    DEGS2 Genopedia 1 0
    ADORA1 Genopedia 1 0
    AFAP1L1 Genopedia 1 0
    AANAT Genopedia 1 0
    TMEM161B Genopedia 1 0
    ADA Genopedia 1 0
    TSNAX-DISC1 Genopedia 1 0
    ST3GAL6 Genopedia 1 0
    PDE10A Genopedia 1 0
    CNTNAP2 Genopedia 1 0
    GFRA1 Genopedia 1 0
    ITGB3 Genopedia 1 0
    L1CAM Genopedia 1 0
    LEP Genopedia 1 0
    FADS1 Genopedia 1 0
    OR7E26P Genopedia 1 1
    LTA Genopedia 1 0
    ACCN2 Genopedia 1 0
    MEF2C Genopedia 1 0
    ABCG1 Genopedia 1 0
    NLRP12 Genopedia 1 0
    MAGI1 Genopedia 1 0
    PCDH9 Genopedia 1 0
    LEF1 Genopedia 1 0
    PDE4B Genopedia 1 0
    ABCB4 Genopedia 1 0
    IGF1 Genopedia 1 0
    MTNR1A Genopedia 1 0
    SLC4A10 Genopedia 1 0
    NRAS Genopedia 1 0
    NRGN Genopedia 1 1
    SAGE1 Genopedia 1 0
    ATF7IP Genopedia 1 0
    PSMA7 Genopedia 1 0
    PSMB4 Genopedia 1 0
    CD38 Genopedia 1 0
    DMTF1 Genopedia 1 1
    BHLHE40 Genopedia 1 0
    PDE5A Genopedia 1 0
    NRP1 Genopedia 1 0
    ND6 Genopedia 1 0
    STK3 Genopedia 1 0
    TAP2 Genopedia 1 0
    TCF4 Genopedia 1 0
    TEF Genopedia 1 0
    APOO Genopedia 1 0
    NR4A3 Genopedia 1 0
    TNKS2 Genopedia 1 0
    AXIN2 Genopedia 1 0
    PABPC4L Genopedia 1 0
    SGCZ Genopedia 1 0
    GRIK2 Genopedia 1 0
    CMYA5 Genopedia 1 0
    PTK2B Genopedia 1 0
    EFEMP1 Genopedia 1 0
    TBC1D1 Genopedia 1 0
    GABRP Genopedia 1 0
    TBX21 Genopedia 1 0
    GZMK Genopedia 1 0
    HTR2B Genopedia 1 0
    ITGB1 Genopedia 1 0
    JARID2 Genopedia 1 0
    MC2R Genopedia 1 0
    CUX1 Genopedia 1 0
    CYP27A1 Genopedia 1 0
    IL28RA Genopedia 1 0
    DIO3 Genopedia 1 0
    MIR1202 Genopedia 1 0
    TOMM40 Genopedia 1 0
    NRG3 Genopedia 1 0
    CHL1 Genopedia 1 0
    IL24 Genopedia 1 0
    ADCY5 Genopedia 1 0
    ADCY6 Genopedia 1 0
    ADCYAP1R1 Genopedia 1 0
    CACNA1A Genopedia 1 1
    KCNIP4 Genopedia 1 0
    TRPA1 Genopedia 1 0
    UCN2 Genopedia 1 0
    PPIG Genopedia 1 0
    SRR Genopedia 1 0
    SLIT3 Genopedia 1 0
    TNFRSF1B Genopedia 1 0
    TSC2 Genopedia 1 0
    WFS1 Genopedia 1 1
    UST Genopedia 1 0
    CDH17 Genopedia 1 0
    PDLIM5 Genopedia 1 0
    CPLX2 Genopedia 1 0
    OR4B1 Genopedia 1 0
    ADORA2A Genopedia 1 0
    NQO1 Genopedia 1 0
    EGFR Genopedia 1 0
    ELAVL1 Genopedia 1 0
    PARP14 Genopedia 1 0
    PSEN1 Genopedia 1 0
    PSMD13 Genopedia 1 0
    BCL9 Genopedia 1 0
    NTSR1 Genopedia 1 0
    TMEM66 Genopedia 1 0
    IGFBP3 Genopedia 1 0
    GAD2 Genopedia 1 0
    GRIK1 Genopedia 1 0
    APC Genopedia 1 0
    HP Genopedia 1 0
    MIR19A Genopedia 1 0
    ATXN3 Genopedia 1 0
    NDUFV2 Genopedia 1 0
    NFATC2 Genopedia 1 0
    GRIN2A Genopedia 1 0
    MTRR Genopedia 1 0
    ELAVL4 Genopedia 1 0
    SLC29A1 Genopedia 1 0
    LGSN Genopedia 1 0
    PGC Genopedia 1 0
    AVPR1A Genopedia 1 0
    PRKCH Genopedia 1 0
    PRNP Genopedia 1 1
    PSME2 Genopedia 1 0
    PTGS2 Genopedia 1 0
    DPP10 Genopedia 1 0
    SLCO6A1 Genopedia 1 0
    CREM Genopedia 1 0
    CSF2RB Genopedia 1 0
    CYP2B6 Genopedia 1 0
    ADAR Genopedia 1 0
    ADCY1 Genopedia 1 0
    FOXN3 Genopedia 1 0
    PRKCDBP Genopedia 1 0
    ADCY7 Genopedia 1 0
    ADCY8 Genopedia 1 0
    SMCHD1 Genopedia 1 0
    CRTC1 Genopedia 1 0
    GABRA2 Genopedia 1 0
    TIPRL Genopedia 1 1
    DAOA-AS1 Genopedia 1 0
    NKPD1 Genopedia 1 1
    GPX1 Genopedia 1 0
    NT5E Genopedia 1 0
    RP1 Genopedia 1 0
    S100A10 Genopedia 1 0
    BHLHE41 Genopedia 1 0
    ACSS3 Genopedia 1 0
    ZNF385D Genopedia 1 0
    PAPLN Genopedia 1 0
    SLC28A1 Genopedia 1 0
    SLC7A4 Genopedia 1 0
    SLC16A2 Genopedia 1 0
    VAMP2 Genopedia 1 0
    TARBP2 Genopedia 1 0
    TGFBR2 Genopedia 1 0
    ZNF80 Genopedia 1 0
    FOXP2 Genopedia 1 0
    HOMER1 Genopedia 1 0
    TTR Genopedia 1 0
    CACNA1D Genopedia 1 0
    REEP5 Genopedia 1 0
    C7orf23 Genopedia 1 1
    FAT4 Genopedia 1 1
    FZD3 Genopedia 1 0
    OR2G2 Genopedia 1 1
    CADPS Genopedia 1 0
    TIMELESS Genopedia 1 0
    SLC28A2 Genopedia 1 0
    NT5C1B Genopedia 1 0
    STAC Genopedia 1 0
    STIM1 Genopedia 1 0
    SULT2A1 Genopedia 1 0
    TERC Genopedia 1 0
    SLC5A4 Genopedia 1 0
    BMP5 Genopedia 1 0
    BMP7 Genopedia 1 0
    PCNT Genopedia 1 0
    PDE2A Genopedia 1 0
    PLXNA2 Genopedia 1 0
    SLC2A9 Genopedia 1 0
    RGMA Genopedia 1 0
    DTWD1 Genopedia 1 0
    HTR3D Genopedia 1 0
    ENPEP Genopedia 1 0
    ERBB4 Genopedia 1 0
    SLC29A4 Genopedia 1 0
    DBP Genopedia 1 0
    PRICKLE2 Genopedia 1 0
    CYP3A4 Genopedia 1 0
    CDH10 Genopedia 1 0
    CDH13 Genopedia 1 0
    ADRA1A Genopedia 1 0
    ADRB3 Genopedia 1 0
    VPS33B Genopedia 1 0
    GDNF Genopedia 1 0
    ZBTB32 Genopedia 1 0
    HTR3E Genopedia 1 0
    GRM8 Genopedia 1 1
    ANKK1 Genopedia 1 0
    FASLG Genopedia 1 0
    IDO1 Genopedia 1 0
    ITIH1 Genopedia 1 0
    ARRB1 Genopedia 1 0
    ARRB2 Genopedia 1 0
    MAP2K7 Genopedia 1 0
    SLC17A7 Genopedia 1 0
    AS3MT Genopedia 1 0
    RNR1 Genopedia 1 0
    ROBO2 Genopedia 1 0
    RPS6KA2 Genopedia 1 0
    PRDM1 Genopedia 1 0
    SLC6A1 Genopedia 1 0
    SORL1 Genopedia 1 1
    CYTB Genopedia 1 0
    ND4L Genopedia 1 0
    ND2 Genopedia 1 0
    SYN2 Genopedia 1 0
    TLR4 Genopedia 1 0
    WNT7A Genopedia 1 0
    SDPR Genopedia 1 0
    EIF2B2 Genopedia 1 0
    LGI1 Genopedia 1 0
    NRXN3 Genopedia 1 0
    GAP43 Genopedia 1 0
    MDGA1 Genopedia 1 0
    AHCY Genopedia 1 0
    FGF9 Genopedia 1 0
    C10orf32 Genopedia 1 0
    ADK Genopedia 1 0
    ABCB6 Genopedia 1 0
    CDH12 Genopedia 1 0
    SEC23IP Genopedia 1 0
    PXDNL Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    CTNND2 Genopedia 1 0
    ABCA13 Genopedia 1 0
    DCC Genopedia 1 0
    FREM3 Genopedia 1 0
    HTR3C Genopedia 1 0
    ADAMTS16 Genopedia 1 0
    MMP8 Genopedia 1 0
    NTRK3 Genopedia 1 0
    PAWR Genopedia 1 0
    PGF Genopedia 1 0
    PON1 Genopedia 1 0
    ELP3 Genopedia 1 0
    CSGALNACT1 Genopedia 1 0
    VSTM5 Genopedia 1 1
    GSTK1 Genopedia 1 0
    SLC29A2 Genopedia 1 0
    HSPA1B Genopedia 1 0
    PCDH17 Genopedia 1 0
    IGLV2-8 Genopedia 1 0
    TCF7L2 Genopedia 1 0
    TCTA Genopedia 1 0
    TFCP2 Genopedia 1 0
    TSPO Genopedia 1 0
    XBP1 Genopedia 1 0
    PKP4 Genopedia 1 0
    DLK1 Genopedia 1 0
    KALRN Genopedia 1 0
    SLC6A5 Genopedia 1 0
    DDX21 Genopedia 1 0
    FADS2 Genopedia 1 0
    UBE3C Genopedia 1 0
    GPRIN2 Genopedia 1 0
    CDC25B Genopedia 1 0
    GRIN2B Genopedia 1 0
    APAF1 Genopedia 1 0
    TAAR6 Genopedia 1 0
    MIR182 Genopedia 1 0
    MIR30E Genopedia 1 0
    M6PR Genopedia 1 0
    MAOB Genopedia 1 0
    OR1D2 Genopedia 1 1
    SERPINE1 Genopedia 1 0
    RHCG Genopedia 1 0
    PDE6C Genopedia 1 0
    FIGN Genopedia 1 0
    CCBL2 Genopedia 1 0
    ARNTL2 Genopedia 1 0
    TBX20 Genopedia 1 0
    WDFY4 Genopedia 1 0
    RGS4 Genopedia 1 0
    RPS6KA1 Genopedia 1 0
    MDGA2 Genopedia 1 0
    CNTF Genopedia 1 0
    CSNK1E Genopedia 1 0
    HPRTP4 Genopedia 1 1
    CDH7 Genopedia 1 1
    TSPAN5 Genopedia 1 1
    SIGMAR1 Genopedia 1 0
    ADARB1 Genopedia 1 0
    KLHL2 Genopedia 1 1
    DVL2 Genopedia 1 0
    EPHB1 Genopedia 1 0
    FABP2 Genopedia 1 0
    ACSL4 Genopedia 1 0
    MYT1L Genopedia 1 0
    Slc6a4 Genopedia 1 0
    PRPF31 Genopedia 1 1
    ZBTB20 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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