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Phenopedia


Depressive Disorder, Major

573 genes has been reported with Depressive Disorder, Major
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Associated Gene
Total Publication
Meta-analysis Publication
    SLC6A4 Genopedia 216 6
    BDNF Genopedia 109 6
    COMT Genopedia 60 3
    HTR2A Genopedia 58 8
    HTR1A Genopedia 49 3
    TPH1 Genopedia 34 6
    TPH2 Genopedia 33 2
    SLC6A2 Genopedia 32 4
    MAOA Genopedia 28 3
    CYP2D6 Genopedia 25 0
    NR3C1 Genopedia 23 0
    FKBP5 Genopedia 22 2
    ABCB1 Genopedia 22 2
    APOE Genopedia 21 1
    GNB3 Genopedia 19 3
    CRHR1 Genopedia 19 1
    CREB1 Genopedia 17 1
    MTHFR Genopedia 16 1
    CACNA1C Genopedia 15 4
    ACE Genopedia 14 1
    DRD2 Genopedia 14 0
    CYP2C19 Genopedia 13 0
    GSK3B Genopedia 13 0
    SLC6A3 Genopedia 12 1
    PCLO Genopedia 11 1
    HTR1B Genopedia 10 0
    CLOCK Genopedia 10 1
    NTRK2 Genopedia 9 0
    MDD1 Genopedia 9 0
    DRD3 Genopedia 9 1
    DRD4 Genopedia 9 0
    IL1B Genopedia 8 1
    GRM7 Genopedia 8 2
    TNF Genopedia 8 0
    DISC1 Genopedia 7 0
    NRG1 Genopedia 7 1
    HTR2C Genopedia 6 0
    HTR6 Genopedia 6 2
    IL6 Genopedia 6 0
    AGTR1 Genopedia 6 0
    CYP2C9 Genopedia 6 0
    CYP1A2 Genopedia 6 0
    VEGFA Genopedia 6 0
    DTNBP1 Genopedia 6 0
    P2RX7 Genopedia 6 0
    FTO Genopedia 5 2
    ADRA2A Genopedia 5 0
    CRY2 Genopedia 5 0
    CNR1 Genopedia 5 0
    IL10 Genopedia 5 0
    HTT Genopedia 5 0
    ANK3 Genopedia 5 2
    GRIK4 Genopedia 5 0
    DAOA Genopedia 5 0
    GRIA4 Genopedia 4 0
    HTR3A Genopedia 4 1
    IFNG Genopedia 4 0
    CRHR2 Genopedia 4 0
    DBH Genopedia 4 0
    DRD1 Genopedia 4 0
    ESR1 Genopedia 4 0
    BICC1 Genopedia 4 1
    OPRM1 Genopedia 4 0
    NGFR Genopedia 4 0
    SLC6A15 Genopedia 4 1
    AVPR1B Genopedia 4 0
    OXTR Genopedia 4 0
    PTPRR Genopedia 3 0
    CCL2 Genopedia 3 0
    NCAM1 Genopedia 3 0
    GAL Genopedia 3 1
    POMC Genopedia 3 0
    CACNB2 Genopedia 3 1
    PER3 Genopedia 3 0
    PER2 Genopedia 3 0
    TSNAX Genopedia 3 0
    GPR50 Genopedia 3 0
    ZNF804A Genopedia 3 1
    HTR3B Genopedia 3 1
    ESR2 Genopedia 3 0
    EGF Genopedia 3 0
    ADSL Genopedia 3 1
    CRP Genopedia 3 1
    CRY1 Genopedia 3 0
    CRH Genopedia 3 0
    CRHBP Genopedia 3 0
    IL2 Genopedia 3 0
    IL11 Genopedia 3 0
    AR Genopedia 3 0
    EHD3 Genopedia 3 0
    NR3C2 Genopedia 3 0
    LSAMP Genopedia 3 0
    GRN Genopedia 3 1
    GABRA6 Genopedia 3 0
    GABRG2 Genopedia 2 0
    GAD1 Genopedia 2 0
    FGF2 Genopedia 2 0
    FGFR2 Genopedia 2 0
    NLGN1 Genopedia 2 1
    SYNE1 Genopedia 2 2
    GRIK3 Genopedia 2 1
    ANPEP Genopedia 2 0
    CTNNA3 Genopedia 2 1
    IL19 Genopedia 2 0
    GRIA1 Genopedia 2 0
    GRIA2 Genopedia 2 0
    GRIA3 Genopedia 2 0
    GNAS Genopedia 2 0
    PGP Genopedia 2 1
    LEP Genopedia 2 0
    FADS1 Genopedia 2 0
    MAPT Genopedia 2 1
    KCNK2 Genopedia 2 0
    ITIH3 Genopedia 2 1
    ITIH4 Genopedia 2 0
    ARNTL Genopedia 2 0
    HSPA1A Genopedia 2 0
    HTR5A Genopedia 2 0
    GABRA3 Genopedia 2 0
    HSPA1L Genopedia 2 0
    NCAN Genopedia 2 0
    C5orf20 Genopedia 2 1
    CNR2 Genopedia 2 0
    CHRM2 Genopedia 2 0
    ADM Genopedia 2 0
    PPARGC1A Genopedia 2 0
    ADCY3 Genopedia 2 1
    UCN3 Genopedia 2 0
    ADCY9 Genopedia 2 0
    ADCYAP1 Genopedia 2 0
    IDO2 Genopedia 2 0
    DIO1 Genopedia 2 0
    DIO2 Genopedia 2 0
    CTLA4 Genopedia 2 0
    ADRA2C Genopedia 2 0
    ADRB1 Genopedia 2 0
    AKT1 Genopedia 2 0
    FAAH Genopedia 2 0
    AGT Genopedia 2 0
    ELK3 Genopedia 2 1
    PPIG Genopedia 2 0
    ZEB2 Genopedia 2 0
    IKBKE Genopedia 2 0
    NR1D1 Genopedia 2 0
    TGFB1 Genopedia 2 0
    TH Genopedia 2 0
    SLC18A1 Genopedia 2 0
    SNAP25 Genopedia 2 0
    TERT Genopedia 2 0
    C7orf49 Genopedia 2 0
    TP53 Genopedia 2 0
    CCKAR Genopedia 2 0
    YWHAE Genopedia 2 0
    PPP1R1B Genopedia 2 0
    PDE11A Genopedia 2 0
    PDE9A Genopedia 2 0
    PER1 Genopedia 2 0
    MAPK1 Genopedia 2 0
    MAP2K1 Genopedia 2 0
    NOS1 Genopedia 2 0
    NOS3 Genopedia 2 0
    NPY Genopedia 2 0
    NOVA2 Genopedia 2 0
    NPAS2 Genopedia 2 0
    LHPP Genopedia 2 0
    S100B Genopedia 2 0
    SAT1 Genopedia 2 0
    CSMD1 Genopedia 2 1
    SP4 Genopedia 2 0
    AVP Genopedia 2 0
    PRKCG Genopedia 2 0
    BCL2 Genopedia 2 0
    RORA Genopedia 2 0
    BCR Genopedia 2 0
    PSMD9 Genopedia 2 0
    PSMD13 Genopedia 1 0
    PSME2 Genopedia 1 0
    KIAA1244 Genopedia 1 0
    SLC4A10 Genopedia 1 0
    AS3MT Genopedia 1 0
    PTGS2 Genopedia 1 0
    DPP10 Genopedia 1 0
    KIAA1549 Genopedia 1 0
    WDFY4 Genopedia 1 0
    PTPRD Genopedia 1 0
    SLC29A3 Genopedia 1 0
    STK32B Genopedia 1 0
    SAGE1 Genopedia 1 0
    ATF7IP Genopedia 1 0
    MCTP2 Genopedia 1 0
    CSGALNACT1 Genopedia 1 0
    FIGN Genopedia 1 0
    ELP3 Genopedia 1 0
    AVPR1A Genopedia 1 0
    FANCI Genopedia 1 0
    RPS6KA1 Genopedia 1 0
    RPS6KA2 Genopedia 1 0
    RP1 Genopedia 1 0
    RFX3 Genopedia 1 1
    RGS4 Genopedia 1 0
    RIT2 Genopedia 1 0
    RNR1 Genopedia 1 0
    BCL9 Genopedia 1 0
    ROBO2 Genopedia 1 0
    PRKCH Genopedia 1 0
    GABRQ Genopedia 1 0
    MLL5 Genopedia 1 0
    RBM4 Genopedia 1 0
    SPR Genopedia 1 1
    STAC Genopedia 1 0
    STAR Genopedia 1 0
    STAT3 Genopedia 1 0
    ND6 Genopedia 1 0
    CYTB Genopedia 1 0
    ND4L Genopedia 1 0
    ND2 Genopedia 1 0
    STIM1 Genopedia 1 0
    STK3 Genopedia 1 0
    SULT2A1 Genopedia 1 0
    VAMP2 Genopedia 1 0
    SYN2 Genopedia 1 0
    TAP2 Genopedia 1 0
    TARBP2 Genopedia 1 0
    TCF4 Genopedia 1 0
    TCF7L2 Genopedia 1 0
    TCTA Genopedia 1 0
    TEF Genopedia 1 0
    TERC Genopedia 1 0
    NUCKS1 Genopedia 1 0
    USP46 Genopedia 1 0
    SLC5A4 Genopedia 1 0
    SLC6A1 Genopedia 1 0
    BMP5 Genopedia 1 0
    SLC7A4 Genopedia 1 0
    BMP7 Genopedia 1 0
    SLC16A2 Genopedia 1 0
    S100A10 Genopedia 1 0
    AKTIP Genopedia 1 0
    RGS18 Genopedia 1 0
    SRR Genopedia 1 0
    PRDM1 Genopedia 1 0
    NPY2R Genopedia 1 0
    NRAS Genopedia 1 0
    NRGN Genopedia 1 1
    NT5E Genopedia 1 0
    NOS2 Genopedia 1 0
    NDUFV2 Genopedia 1 0
    NFATC2 Genopedia 1 0
    MTNR1A Genopedia 1 0
    MTNR1B Genopedia 1 0
    MTRR Genopedia 1 0
    PCNT Genopedia 1 0
    LEF1 Genopedia 1 0
    GMIP Genopedia 1 0
    PDE1A Genopedia 1 0
    PDE2A Genopedia 1 0
    PDE4B Genopedia 1 0
    RHCG Genopedia 1 0
    PDE6C Genopedia 1 0
    OR1D2 Genopedia 1 1
    ORM1 Genopedia 1 0
    NTRK3 Genopedia 1 0
    NTSR1 Genopedia 1 0
    SERPINE1 Genopedia 1 0
    IL20 Genopedia 1 0
    PAM Genopedia 1 0
    PAWR Genopedia 1 0
    MAP2K7 Genopedia 1 0
    PRNP Genopedia 1 1
    PRODH Genopedia 1 0
    CCBL2 Genopedia 1 0
    SLC2A9 Genopedia 1 0
    PSEN1 Genopedia 1 0
    CELF4 Genopedia 1 1
    PSMA7 Genopedia 1 0
    PSMB4 Genopedia 1 0
    ARNTL2 Genopedia 1 0
    RGMA Genopedia 1 0
    DTWD1 Genopedia 1 0
    SLC17A7 Genopedia 1 0
    TBX20 Genopedia 1 0
    ACP1 Genopedia 1 0
    PGC Genopedia 1 1
    PGF Genopedia 1 0
    LGSN Genopedia 1 0
    TMEM66 Genopedia 1 0
    PCDH9 Genopedia 1 1
    PON1 Genopedia 1 0
    GNB1L Genopedia 1 0
    PARP14 Genopedia 1 0
    ABCB4 Genopedia 1 0
    PLA2G4A Genopedia 1 0
    ATP6V0A1 Genopedia 1 1
    PLXNA2 Genopedia 1 0
    SNTG2 Genopedia 1 0
    SDPR Genopedia 1 0
    TOX2 Genopedia 1 0
    PKP4 Genopedia 1 0
    BHLHE40 Genopedia 1 0
    KMO Genopedia 1 0
    CADPS Genopedia 1 0
    PDE5A Genopedia 1 0
    DLK1 Genopedia 1 0
    NRP1 Genopedia 1 0
    NR4A3 Genopedia 1 0
    KCNIP4 Genopedia 1 0
    TNKS2 Genopedia 1 0
    FXR1 Genopedia 1 0
    OR2G2 Genopedia 1 1
    Crh Genopedia 1 0
    AXIN2 Genopedia 1 0
    MAD1L1 Genopedia 1 0
    ZNF80 Genopedia 1 0
    CACNA1A Genopedia 1 1
    CACNA1D Genopedia 1 0
    REEP5 Genopedia 1 0
    EIF2B2 Genopedia 1 0
    TIMELESS Genopedia 1 0
    CHRFAM7A Genopedia 1 0
    TRPA1 Genopedia 1 0
    PAPLN Genopedia 1 0
    KALRN Genopedia 1 0
    UCN2 Genopedia 1 0
    SLC6A5 Genopedia 1 0
    SLC28A2 Genopedia 1 0
    SLC28A1 Genopedia 1 0
    CD3E Genopedia 1 0
    NLRP12 Genopedia 1 0
    TFCP2 Genopedia 1 0
    SOD2 Genopedia 1 0
    SORL1 Genopedia 1 1
    SLIT3 Genopedia 1 0
    DLK2 Genopedia 1 0
    TSPO Genopedia 1 0
    TLR4 Genopedia 1 0
    TGFBR2 Genopedia 1 0
    TNFRSF1A Genopedia 1 0
    TNFRSF1B Genopedia 1 0
    TSC2 Genopedia 1 0
    TTR Genopedia 1 0
    UCN Genopedia 1 0
    VCP Genopedia 1 0
    VIP Genopedia 1 0
    VIPR2 Genopedia 1 0
    WFS1 Genopedia 1 1
    WNT7A Genopedia 1 0
    XBP1 Genopedia 1 0
    APOO Genopedia 1 0
    C7orf23 Genopedia 1 1
    BHLHE41 Genopedia 1 0
    OR10R1P Genopedia 1 0
    ACSS3 Genopedia 1 0
    FAT4 Genopedia 1 1
    ZNF385D Genopedia 1 0
    FZD3 Genopedia 1 0
    UBE3C Genopedia 1 0
    GPRIN2 Genopedia 1 0
    MAGI2 Genopedia 1 0
    SV2B Genopedia 1 0
    CDC25B Genopedia 1 0
    DMTF1 Genopedia 1 1
    NRXN3 Genopedia 1 0
    NRXN1 Genopedia 1 0
    FOXP2 Genopedia 1 0
    FADS2 Genopedia 1 0
    NTN1 Genopedia 1 0
    HOMER1 Genopedia 1 0
    CD38 Genopedia 1 0
    DDX21 Genopedia 1 0
    LGI1 Genopedia 1 0
    MAGI1 Genopedia 1 0
    DLGAP1 Genopedia 1 0
    NT5C1B Genopedia 1 0
    NDST3 Genopedia 1 0
    ABCG1 Genopedia 1 0
    HTR3D Genopedia 1 0
    EMP1 Genopedia 1 0
    EMX2 Genopedia 1 0
    CMYA5 Genopedia 1 0
    ENPEP Genopedia 1 0
    SLC29A1 Genopedia 1 0
    EPHB1 Genopedia 1 0
    ERBB4 Genopedia 1 0
    DVL2 Genopedia 1 0
    AGTR2 Genopedia 1 0
    AHCY Genopedia 1 0
    FABP2 Genopedia 1 0
    ACSL4 Genopedia 1 0
    PTK2B Genopedia 1 0
    EFEMP1 Genopedia 1 0
    SLC29A4 Genopedia 1 0
    DBP Genopedia 1 0
    DCC Genopedia 1 0
    EGFR Genopedia 1 0
    ADCY4 Genopedia 1 0
    ELAVL1 Genopedia 1 0
    ELAVL4 Genopedia 1 0
    TMEM161B Genopedia 1 0
    ADRB2 Genopedia 1 0
    CUX1 Genopedia 1 0
    AANAT Genopedia 1 0
    CTNND2 Genopedia 1 0
    ABCA13 Genopedia 1 0
    ADRB3 Genopedia 1 0
    CYP2B6 Genopedia 1 0
    CYP3A4 Genopedia 1 0
    DIO3 Genopedia 1 0
    DPP4 Genopedia 1 0
    DPYD Genopedia 1 0
    HTR3C Genopedia 1 0
    ADAMTS16 Genopedia 1 0
    NQO1 Genopedia 1 0
    CYP27A1 Genopedia 1 0
    SLC35G1 Genopedia 1 1
    DGKH Genopedia 1 0
    MDGA2 Genopedia 1 0
    IL28RA Genopedia 1 0
    DDC Genopedia 1 1
    PRICKLE2 Genopedia 1 0
    FREM3 Genopedia 1 0
    ZNF366 Genopedia 1 0
    ACSM1 Genopedia 1 0
    ADCYAP1R1 Genopedia 1 0
    C10orf32 Genopedia 1 0
    OR4B1 Genopedia 1 0
    TMEM132D Genopedia 1 0
    IL24 Genopedia 1 0
    ADCY5 Genopedia 1 0
    FOXN3 Genopedia 1 0
    SEC23IP Genopedia 1 0
    ADCY6 Genopedia 1 0
    PRKCDBP Genopedia 1 0
    KLHL2 Genopedia 1 1
    ADA Genopedia 1 0
    HPRTP4 Genopedia 1 1
    MIR1202 Genopedia 1 0
    TSNAX-DISC1 Genopedia 1 0
    CDH7 Genopedia 1 1
    LOC100506013 Genopedia 1 0
    ABCB6 Genopedia 1 0
    CDH9 Genopedia 1 0
    CDH10 Genopedia 1 0
    UST Genopedia 1 0
    TSPAN5 Genopedia 1 1
    CDH12 Genopedia 1 0
    CDH13 Genopedia 1 0
    CDH17 Genopedia 1 0
    GPHN Genopedia 1 0
    SIGMAR1 Genopedia 1 0
    ADAR Genopedia 1 0
    ADARB1 Genopedia 1 0
    ST3GAL6 Genopedia 1 0
    TOMM40 Genopedia 1 0
    PDLIM5 Genopedia 1 0
    ADCY1 Genopedia 1 0
    NRG3 Genopedia 1 0
    CHL1 Genopedia 1 0
    ADCY2 Genopedia 1 0
    CPLX2 Genopedia 1 0
    CPLX1 Genopedia 1 0
    PDE10A Genopedia 1 0
    SLCO6A1 Genopedia 1 0
    ADORA1 Genopedia 1 0
    AFAP1L1 Genopedia 1 0
    ADORA2A Genopedia 1 0
    CPM Genopedia 1 0
    SGCZ Genopedia 1 0
    PXDNL Genopedia 1 0
    ADCY7 Genopedia 1 0
    CHRNA7 Genopedia 1 0
    ADCY8 Genopedia 1 0
    CNTF Genopedia 1 0
    DEGS2 Genopedia 1 0
    CNP Genopedia 1 0
    CSF2RB Genopedia 1 0
    CSNK1E Genopedia 1 0
    VCAN Genopedia 1 0
    ADRA1A Genopedia 1 0
    MACROD2 Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    CREBBP Genopedia 1 0
    CREM Genopedia 1 0
    ADK Genopedia 1 0
    PABPC4L Genopedia 1 0
    HTR1D Genopedia 1 0
    HTR2B Genopedia 1 0
    HSPA1B Genopedia 1 0
    CFH Genopedia 1 1
    APAF1 Genopedia 1 0
    SLC29A2 Genopedia 1 0
    TAAR6 Genopedia 1 0
    APC Genopedia 1 0
    HP Genopedia 1 0
    ITGA9 Genopedia 1 0
    ITGB1 Genopedia 1 0
    ITGB3 Genopedia 1 0
    ITIH1 Genopedia 1 0
    IDO1 Genopedia 1 0
    INS Genopedia 1 0
    FASLG Genopedia 1 0
    IL4 Genopedia 1 0
    IGF1 Genopedia 1 0
    SKA2 Genopedia 1 0
    IGFBP3 Genopedia 1 0
    MIR182 Genopedia 1 0
    MIR19A Genopedia 1 0
    MIR30E Genopedia 1 0
    MIR34B Genopedia 1 0
    M6PR Genopedia 1 0
    ARRB1 Genopedia 1 0
    ARRB2 Genopedia 1 0
    ACCN2 Genopedia 1 0
    JARID2 Genopedia 1 0
    GSTK1 Genopedia 1 0
    VSTM5 Genopedia 1 1
    L1CAM Genopedia 1 0
    IL6R Genopedia 1 0
    MC2R Genopedia 1 0
    MEF2C Genopedia 1 0
    ATXN3 Genopedia 1 0
    MMP8 Genopedia 1 0
    ABCC1 Genopedia 1 0
    C15orf53 Genopedia 1 1
    OR7E26P Genopedia 1 1
    LTA Genopedia 1 0
    MAOB Genopedia 1 0
    NKPD1 Genopedia 1 1
    HTR3E Genopedia 1 0
    GPX1 Genopedia 1 0
    PCDH17 Genopedia 1 0
    GRID2 Genopedia 1 0
    IGLV2-8 Genopedia 1 0
    DAOA-AS1 Genopedia 1 0
    TBX21 Genopedia 1 0
    NXPH1 Genopedia 1 0
    GZMK Genopedia 1 0
    GRM8 Genopedia 1 1
    Htt Genopedia 1 0
    GRM4 Genopedia 1 0
    GRIN2A Genopedia 1 0
    GRIN2B Genopedia 1 0
    GRIK1 Genopedia 1 0
    GRIK2 Genopedia 1 0
    SMCHD1 Genopedia 1 0
    CRTC1 Genopedia 1 0
    SIRT1 Genopedia 1 0
    GRIP1 Genopedia 1 0
    ANKK1 Genopedia 1 0
    GABRA2 Genopedia 1 0
    Slc6a4 Genopedia 1 0
    FGF9 Genopedia 1 0
    FGF14 Genopedia 1 0
    SACM1L Genopedia 1 0
    MYT1L Genopedia 1 0
    CLASP2 Genopedia 1 0
    TBC1D1 Genopedia 1 0
    GAD2 Genopedia 1 0
    C11orf41 Genopedia 1 0
    BRP44 Genopedia 1 1
    GAP43 Genopedia 1 0
    CNTNAP2 Genopedia 1 0
    PRPF31 Genopedia 1 1
    ZBTB20 Genopedia 1 0
    TIPRL Genopedia 1 1
    VPS33B Genopedia 1 0
    GCH1 Genopedia 1 0
    MDGA1 Genopedia 1 0
    GDNF Genopedia 1 0
    GABRP Genopedia 1 0
    GABRE Genopedia 1 0
    GFRA1 Genopedia 1 0
    ZBTB32 Genopedia 1 0
    LAT Genopedia 1 1
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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