|
Depressive Disorder, Major
|
|
|
|
595 genes has been reported with Depressive Disorder, Major
|
[Click  to re-sort the table]
|
|
|
|
Meta-analysis Publication
|
SLC6A4
|
222
|
6
|
| BDNF
|
111
|
6
|
| COMT
|
62
|
3
|
| HTR2A
|
59
|
8
|
| HTR1A
|
50
|
3
|
| TPH2
|
34
|
2
|
| TPH1
|
34
|
6
|
| SLC6A2
|
33
|
4
|
| MAOA
|
28
|
3
|
| CYP2D6
|
25
|
0
|
| FKBP5
|
25
|
2
|
| NR3C1
|
23
|
0
|
| ABCB1
|
22
|
2
|
| APOE
|
21
|
1
|
| GNB3
|
19
|
3
|
| CRHR1
|
19
|
1
|
| CREB1
|
17
|
1
|
| MTHFR
|
16
|
1
|
| CACNA1C
|
16
|
4
|
| DRD2
|
14
|
0
|
| GSK3B
|
14
|
0
|
| ACE
|
14
|
1
|
| CYP2C19
|
13
|
0
|
| SLC6A3
|
13
|
1
|
| PCLO
|
11
|
1
|
| HTR1B
|
11
|
0
|
| CLOCK
|
10
|
1
|
| GRM7
|
10
|
2
|
| NTRK2
|
9
|
0
|
| DRD3
|
9
|
1
|
| TNF
|
9
|
0
|
| DRD4
|
9
|
0
|
| MDD1
|
9
|
0
|
| P2RX7
|
8
|
0
|
| IL1B
|
8
|
1
|
| DISC1
|
7
|
0
|
| VEGFA
|
7
|
0
|
| NRG1
|
7
|
1
|
| HTR6
|
6
|
2
|
| IL6
|
6
|
0
|
| CYP2C9
|
6
|
0
|
| HTT
|
6
|
0
|
| ANK3
|
6
|
2
|
| AGTR1
|
6
|
0
|
| DTNBP1
|
6
|
0
|
| CYP1A2
|
6
|
0
|
| HTR2C
|
6
|
0
|
| CRY2
|
5
|
0
|
| FTO
|
5
|
2
|
| DAOA
|
5
|
0
|
| ADRA2A
|
5
|
0
|
| GRIK4
|
5
|
0
|
| CNR1
|
5
|
0
|
| IL10
|
5
|
0
|
| GRIA4
|
4
|
0
|
| CRHR2
|
4
|
0
|
| ESR1
|
4
|
0
|
| POMC
|
4
|
0
|
| HTR3A
|
4
|
1
|
| DBH
|
4
|
0
|
| DRD1
|
4
|
0
|
| SLC6A15
|
4
|
1
|
| CACNB2
|
4
|
1
|
| OPRM1
|
4
|
0
|
| CRP
|
4
|
1
|
| BICC1
|
4
|
1
|
| OXTR
|
4
|
0
|
| AVPR1B
|
4
|
0
|
| NGFR
|
4
|
0
|
| IFNG
|
4
|
0
|
| GABRA6
|
3
|
0
|
| GAL
|
3
|
1
|
| LSAMP
|
3
|
0
|
| GRN
|
3
|
1
|
| CRH
|
3
|
0
|
| ADRB1
|
3
|
0
|
| CRY1
|
3
|
0
|
| SP4
|
3
|
1
|
| EGF
|
3
|
0
|
| GPR50
|
3
|
0
|
| ESR2
|
3
|
0
|
| AR
|
3
|
0
|
| EHD3
|
3
|
0
|
| HTR3B
|
3
|
1
|
| SYNE1
|
3
|
2
|
| IL11
|
3
|
0
|
| RORA
|
3
|
0
|
| NCAM1
|
3
|
0
|
| ITIH3
|
3
|
1
|
| CRHBP
|
3
|
0
|
| ZNF804A
|
3
|
1
|
| PER2
|
3
|
0
|
| PTPRR
|
3
|
0
|
| CCL2
|
3
|
0
|
| TSNAX
|
3
|
0
|
| ADSL
|
3
|
1
|
| LEP
|
3
|
0
|
| IL2
|
3
|
0
|
| NR3C2
|
3
|
0
|
| PER3
|
3
|
0
|
| NR1D1
|
2
|
0
|
| GRIA2
|
2
|
0
|
| CSMD1
|
2
|
1
|
| TERT
|
2
|
0
|
| PPP1R1B
|
2
|
0
|
| CCKAR
|
2
|
0
|
| CTNNA3
|
2
|
1
|
| MAPT
|
2
|
1
|
| FAAH
|
2
|
0
|
| CHRM2
|
2
|
0
|
| ADCY9
|
2
|
0
|
| GABRG2
|
2
|
0
|
| NPAS2
|
2
|
0
|
| AVP
|
2
|
0
|
| AKT1
|
2
|
0
|
| S100B
|
2
|
0
|
| TP53
|
2
|
0
|
| TCF4
|
2
|
0
|
| HOMER1
|
2
|
0
|
| NOS3
|
2
|
0
|
| NPY
|
2
|
0
|
| NOVA2
|
2
|
0
|
| CTLA4
|
2
|
0
|
| INS
|
2
|
0
|
| CNR2
|
2
|
0
|
| AGT
|
2
|
0
|
| BCL2
|
2
|
0
|
| SLTM
|
2
|
0
|
| NCAN
|
2
|
0
|
| PPARGC1A
|
2
|
0
|
| UCN3
|
2
|
0
|
| FGF2
|
2
|
0
|
| GABRA3
|
2
|
0
|
| HSPA1A
|
2
|
0
|
| PER1
|
2
|
0
|
| SAT1
|
2
|
0
|
| PRKCG
|
2
|
0
|
| LOC100506013
|
2
|
0
|
| TGFB1
|
2
|
0
|
| ARNTL
|
2
|
0
|
| GRIA1
|
2
|
0
|
| GRIA3
|
2
|
0
|
| FADS1
|
2
|
0
|
| SNAP25
|
2
|
0
|
| PGP
|
2
|
1
|
| PDE9A
|
2
|
0
|
| DIO2
|
2
|
0
|
| NLGN1
|
2
|
1
|
| YWHAE
|
2
|
0
|
| GNAS
|
2
|
0
|
| IDO2
|
2
|
0
|
| IL19
|
2
|
0
|
| ITIH4
|
2
|
0
|
| FGFR2
|
2
|
0
|
| ADCYAP1
|
2
|
0
|
| LHPP
|
2
|
0
|
| PDE11A
|
2
|
0
|
| DIO1
|
2
|
0
|
| C5orf20
|
2
|
1
|
| ELK3
|
2
|
1
|
| NOS1
|
2
|
0
|
| TH
|
2
|
0
|
| PPIG
|
2
|
0
|
| ZEB2
|
2
|
0
|
| GSK3A
|
2
|
0
|
| ADRA2C
|
2
|
0
|
| CHL1
|
2
|
0
|
| GAD1
|
2
|
0
|
| PSMD9
|
2
|
0
|
| GRIK3
|
2
|
1
|
| BCR
|
2
|
0
|
| SLC18A1
|
2
|
0
|
| HSPA1L
|
2
|
0
|
| MAPK1
|
2
|
0
|
| MAP2K1
|
2
|
0
|
| HTR5A
|
2
|
0
|
| ANPEP
|
2
|
0
|
| ADCY3
|
2
|
1
|
| ADM
|
2
|
0
|
| KCNK2
|
2
|
0
|
| C7orf49
|
2
|
0
|
| IKBKE
|
2
|
0
|
| SDPR
|
1
|
0
|
| TOX2
|
1
|
0
|
| EIF2B2
|
1
|
0
|
| MAGI1
|
1
|
0
|
| NRXN3
|
1
|
0
|
| ABCG1
|
1
|
0
|
| OR7E26P
|
1
|
1
|
| ACCN2
|
1
|
0
|
| MMP8
|
1
|
0
|
| OXT
|
1
|
0
|
| ADORA1
|
1
|
0
|
| TMEM161B
|
1
|
0
|
| ABCA13
|
1
|
0
|
| C10orf32
|
1
|
0
|
| ADK
|
1
|
0
|
| TSNAX-DISC1
|
1
|
0
|
| ABCB6
|
1
|
0
|
| ST3GAL6
|
1
|
0
|
| SLC29A2
|
1
|
0
|
| GAP43
|
1
|
0
|
| GFRA1
|
1
|
0
|
| PCDH17
|
1
|
0
|
| CELF4
|
1
|
1
|
| RNR1
|
1
|
0
|
| RPS6KA2
|
1
|
0
|
| PRDM1
|
1
|
0
|
| USP46
|
1
|
0
|
| SORL1
|
1
|
1
|
| CYTB
|
1
|
0
|
| UCN
|
1
|
0
|
| WNT7A
|
1
|
0
|
| GMIP
|
1
|
0
|
| PDE1A
|
1
|
0
|
| PGF
|
1
|
0
|
| PLA2G4A
|
1
|
0
|
| PON1
|
1
|
0
|
| ELP3
|
1
|
0
|
| MCTP2
|
1
|
0
|
| SKA2
|
1
|
0
|
| C15orf53
|
1
|
1
|
| NXPH1
|
1
|
0
|
| TSPAN5
|
1
|
1
|
| SIGMAR1
|
1
|
0
|
| ADCY2
|
1
|
0
|
| CHRNA4
|
1
|
0
|
| CPM
|
1
|
0
|
| DGKH
|
1
|
0
|
| MDGA2
|
1
|
0
|
| DPYD
|
1
|
0
|
| FABP2
|
1
|
0
|
| GABRE
|
1
|
0
|
| ZBTB20
|
1
|
0
|
| MIR182
|
1
|
0
|
| IL20
|
1
|
0
|
| SNTG2
|
1
|
0
|
| ARNTL2
|
1
|
0
|
| TBX20
|
1
|
0
|
| KIAA1244
|
1
|
0
|
| DLK2
|
1
|
0
|
| TCF7L2
|
1
|
0
|
| TCTA
|
1
|
0
|
| CHRFAM7A
|
1
|
0
|
| KALRN
|
1
|
0
|
| MAGI2
|
1
|
0
|
| ND6
|
1
|
0
|
| TARBP2
|
1
|
0
|
| TGFBR2
|
1
|
0
|
| ANKDD1B
|
1
|
0
|
| ZNF80
|
1
|
0
|
| ZNF385D
|
1
|
0
|
| TNKS2
|
1
|
0
|
| AXIN2
|
1
|
0
|
| MAD1L1
|
1
|
0
|
| BHLHE40
|
1
|
0
|
| PDE5A
|
1
|
0
|
| NTN1
|
1
|
0
|
| CD38
|
1
|
0
|
| DMTF1
|
1
|
1
|
| TOMM40
|
1
|
0
|
| NKPD1
|
1
|
1
|
| GZMK
|
1
|
0
|
| IL5
|
1
|
0
|
| ITGB1
|
1
|
0
|
| NRAS
|
1
|
0
|
| NRGN
|
1
|
1
|
| PSME2
|
1
|
0
|
| BCL2A1
|
1
|
0
|
| RP1
|
1
|
0
|
| AVPR1A
|
1
|
0
|
| SLC16A2
|
1
|
0
|
| TIPRL
|
1
|
1
|
| IL28RA
|
1
|
0
|
| DVL3
|
1
|
0
|
| SLC29A1
|
1
|
0
|
| EFEMP1
|
1
|
0
|
| SMCHD1
|
1
|
0
|
| CRTC1
|
1
|
0
|
| ADCY5
|
1
|
0
|
| FOXN3
|
1
|
0
|
| ADCY8
|
1
|
0
|
| CYP2B6
|
1
|
0
|
| KCNIP4
|
1
|
0
|
| OR2G2
|
1
|
1
|
| TRPA1
|
1
|
0
|
| UCN2
|
1
|
0
|
| TSC2
|
1
|
0
|
| CACNA1A
|
1
|
1
|
| CACNA1D
|
1
|
0
|
| FAT4
|
1
|
1
|
| FZD3
|
1
|
0
|
| STAC
|
1
|
0
|
| SULT2A1
|
1
|
0
|
| TERC
|
1
|
0
|
| PCNT
|
1
|
0
|
| PDE2A
|
1
|
0
|
| PLXNA2
|
1
|
0
|
| PARP14
|
1
|
0
|
| DTWD1
|
1
|
0
|
| RBM4
|
1
|
0
|
| SLC5A4
|
1
|
0
|
| BMP7
|
1
|
0
|
| SLIT3
|
1
|
0
|
| HTR3D
|
1
|
0
|
| ENPEP
|
1
|
0
|
| GAD2
|
1
|
0
|
| GDNF
|
1
|
0
|
| ZBTB32
|
1
|
0
|
| IGFBP3
|
1
|
0
|
| ARRB1
|
1
|
0
|
| NDUFV2
|
1
|
0
|
| CYP3A4
|
1
|
0
|
| ADORA2A
|
1
|
0
|
| UST
|
1
|
0
|
| CDH13
|
1
|
0
|
| EGFR
|
1
|
0
|
| ZNF366
|
1
|
0
|
| GPHA2
|
1
|
0
|
| NQO1
|
1
|
0
|
| PCDH9
|
1
|
1
|
| LEF1
|
1
|
0
|
| PDE4B
|
1
|
0
|
| LGSN
|
1
|
0
|
| ABCB4
|
1
|
0
|
| PRKCH
|
1
|
0
|
| PRNP
|
1
|
1
|
| PSMA7
|
1
|
0
|
| PSMB4
|
1
|
0
|
| SLC4A10
|
1
|
0
|
| PTGS2
|
1
|
0
|
| DPP10
|
1
|
0
|
| SLC7A4
|
1
|
0
|
| STK3
|
1
|
0
|
| NRP1
|
1
|
0
|
| PAPLN
|
1
|
0
|
| SLC28A1
|
1
|
0
|
| CMYA5
|
1
|
0
|
| PABPC4L
|
1
|
0
|
| CREM
|
1
|
0
|
| CUX1
|
1
|
0
|
| DIO3
|
1
|
0
|
| ADCY1
|
1
|
0
|
| NRG3
|
1
|
0
|
| IL24
|
1
|
0
|
| ADCY7
|
1
|
0
|
| GABRA2
|
1
|
0
|
| GABRP
|
1
|
0
|
| C11orf41
|
1
|
0
|
| TBX21
|
1
|
0
|
| IGF1
|
1
|
0
|
| MTRR
|
1
|
0
|
| NDUFB2
|
1
|
0
|
| NT5E
|
1
|
0
|
| MIR19A
|
1
|
0
|
| ATXN3
|
1
|
0
|
| NFATC2
|
1
|
0
|
| NTSR1
|
1
|
0
|
| TMEM66
|
1
|
0
|
| ERBB4
|
1
|
0
|
| VPS33B
|
1
|
0
|
| CDH17
|
1
|
0
|
| PDLIM5
|
1
|
0
|
| CPLX2
|
1
|
0
|
| VCAN
|
1
|
0
|
| ADRA1A
|
1
|
0
|
| DBP
|
1
|
0
|
| PRICKLE2
|
1
|
0
|
| GRIK1
|
1
|
0
|
| PSEN1
|
1
|
0
|
| PSMD13
|
1
|
0
|
| SRR
|
1
|
0
|
| BMP5
|
1
|
0
|
| STIM1
|
1
|
0
|
| KCNK5
|
1
|
0
|
| SLC28A2
|
1
|
0
|
| KIAA0020
|
1
|
0
|
| HP
|
1
|
0
|
| WFS1
|
1
|
1
|
| CNTNAP2
|
1
|
0
|
| ADA
|
1
|
0
|
| CDH12
|
1
|
0
|
| PDE10A
|
1
|
0
|
| AHCY
|
1
|
0
|
| ADCY4
|
1
|
0
|
| EMX2
|
1
|
0
|
| FGF9
|
1
|
0
|
| DCC
|
1
|
0
|
| FREM3
|
1
|
0
|
| ADAMTS16
|
1
|
0
|
| AFAP1L1
|
1
|
0
|
| PXDNL
|
1
|
0
|
| ADAMTS14
|
1
|
0
|
| AANAT
|
1
|
0
|
| ATP6V1B2
|
1
|
1
|
| CSGALNACT1
|
1
|
0
|
| GABRQ
|
1
|
0
|
| MLL5
|
1
|
0
|
| SLC17A7
|
1
|
0
|
| PTPN11
|
1
|
0
|
| AKTIP
|
1
|
0
|
| SLC6A1
|
1
|
0
|
| IGLV2-8
|
1
|
0
|
| IL4
|
1
|
0
|
| VSTM5
|
1
|
1
|
| L1CAM
|
1
|
0
|
| SPR
|
1
|
1
|
| ND4L
|
1
|
0
|
| SYN2
|
1
|
0
|
| TLR4
|
1
|
0
|
| LTA
|
1
|
0
|
| NPY2R
|
1
|
0
|
| ORM1
|
1
|
0
|
| FXR1
|
1
|
0
|
| NLRP12
|
1
|
0
|
| TSPO
|
1
|
0
|
| ST8SIA2
|
1
|
0
|
| PKP4
|
1
|
0
|
| SLC6A5
|
1
|
0
|
| CD3E
|
1
|
0
|
| DLGAP1
|
1
|
0
|
| SV2B
|
1
|
0
|
| TNFRSF1A
|
1
|
0
|
| VIPR2
|
1
|
0
|
| XBP1
|
1
|
0
|
| TFCP2
|
1
|
0
|
| NUCKS1
|
1
|
0
|
| ADARB1
|
1
|
0
|
| CPLX1
|
1
|
0
|
| CHRNA7
|
1
|
0
|
| CNP
|
1
|
0
|
| MACROD2
|
1
|
0
|
| CSNK1E
|
1
|
0
|
| SLC35G1
|
1
|
1
|
| GRIP1
|
1
|
0
|
| GRIN2B
|
1
|
0
|
| CFH
|
1
|
1
|
| TAAR6
|
1
|
0
|
| DVL2
|
1
|
0
|
| AGTR2
|
1
|
0
|
| ALDH2
|
1
|
0
|
| MYT1L
|
1
|
0
|
| WDFY4
|
1
|
0
|
| PTPRD
|
1
|
0
|
| RGS4
|
1
|
0
|
| RIT2
|
1
|
0
|
| RPS6KA1
|
1
|
0
|
| M6PR
|
1
|
0
|
| MTNR1B
|
1
|
0
|
| SERPINE1
|
1
|
0
|
| RHCG
|
1
|
0
|
| ATP6V0A1
|
1
|
1
|
| IL1A
|
1
|
0
|
| IL6R
|
1
|
0
|
| HPRTP4
|
1
|
1
|
| CDH7
|
1
|
1
|
| TNFRSF1B
|
1
|
0
|
| TTR
|
1
|
0
|
| REEP5
|
1
|
0
|
| C7orf23
|
1
|
1
|
| SLC2A9
|
1
|
0
|
| RGMA
|
1
|
0
|
| FASLG
|
1
|
0
|
| ATP6V0A2
|
1
|
0
|
| ANKK1
|
1
|
0
|
| ARRB2
|
1
|
0
|
| IDO1
|
1
|
0
|
| ITIH1
|
1
|
0
|
| HTR3E
|
1
|
0
|
| GRM8
|
1
|
1
|
| APC
|
1
|
0
|
| CDH10
|
1
|
0
|
| ADRB3
|
1
|
0
|
| OR4B1
|
1
|
0
|
| ELAVL1
|
1
|
0
|
| SLC29A4
|
1
|
0
|
| CADPS
|
1
|
0
|
| TIMELESS
|
1
|
0
|
| BCL9
|
1
|
0
|
| NT5C1B
|
1
|
0
|
| ELAVL4
|
1
|
0
|
| PTK2B
|
1
|
0
|
| TBC1D1
|
1
|
0
|
| LAT
|
1
|
1
|
| DAOA-AS1
|
1
|
0
|
| GPX1
|
1
|
0
|
| GRIK2
|
1
|
0
|
| SLCO6A1
|
1
|
0
|
| SGCZ
|
1
|
0
|
| CSF2
|
1
|
0
|
| CSF2RB
|
1
|
0
|
| MIR1202
|
1
|
0
|
| ADAR
|
1
|
0
|
| ADCY6
|
1
|
0
|
| PRKCDBP
|
1
|
0
|
| ADCYAP1R1
|
1
|
0
|
| JARID2
|
1
|
0
|
| MC2R
|
1
|
0
|
| CYP27A1
|
1
|
0
|
| GRIN2A
|
1
|
0
|
| HTR2B
|
1
|
0
|
| PGC
|
1
|
1
|
| SAGE1
|
1
|
0
|
| ATF7IP
|
1
|
0
|
| MTNR1A
|
1
|
0
|
| FOXP2
|
1
|
0
|
| APOO
|
1
|
0
|
| BHLHE41
|
1
|
0
|
| ACSS3
|
1
|
0
|
| NR4A3
|
1
|
0
|
| TEF
|
1
|
0
|
| VAMP2
|
1
|
0
|
| TAP2
|
1
|
0
|
| S100A10
|
1
|
0
|
| RGS18
|
1
|
0
|
| SOD2
|
1
|
0
|
| STAR
|
1
|
0
|
| STAT3
|
1
|
0
|
| VCP
|
1
|
0
|
| VIP
|
1
|
0
|
| Crh
|
1
|
0
|
| KMO
|
1
|
0
|
| DLK1
|
1
|
0
|
| DDX21
|
1
|
0
|
| NDST3
|
1
|
0
|
| NRXN1
|
1
|
0
|
| FADS2
|
1
|
0
|
| UBE3C
|
1
|
0
|
| GPRIN2
|
1
|
0
|
| CDC25B
|
1
|
0
|
| GNB1L
|
1
|
0
|
| FIGN
|
1
|
0
|
| FANCI
|
1
|
0
|
| STK32B
|
1
|
0
|
| PRL
|
1
|
0
|
| PRODH
|
1
|
0
|
| CCBL2
|
1
|
0
|
| NTF3
|
1
|
0
|
| OR1D2
|
1
|
1
|
| PAM
|
1
|
0
|
| PDE6C
|
1
|
0
|
| ACP1
|
1
|
0
|
| ITGA9
|
1
|
0
|
| MIR30E
|
1
|
0
|
| MIR34B
|
1
|
0
|
| MAOB
|
1
|
0
|
| NOS2
|
1
|
0
|
| APAF1
|
1
|
0
|
| HTR1D
|
1
|
0
|
| BRP44
|
1
|
1
|
| PRPF31
|
1
|
1
|
| GCH1
|
1
|
0
|
| GRM4
|
1
|
0
|
| ACSL4
|
1
|
0
|
| FGF14
|
1
|
0
|
| CLASP2
|
1
|
0
|
| Slc6a4
|
1
|
0
|
| DPP4
|
1
|
0
|
| EPHB1
|
1
|
0
|
| ADRB2
|
1
|
0
|
| CNTF
|
1
|
0
|
| CREBBP
|
1
|
0
|
| CDH9
|
1
|
0
|
| KLHL2
|
1
|
1
|
| ACSM1
|
1
|
0
|
| TMEM132D
|
1
|
0
|
| DEGS2
|
1
|
0
|
| CTNND2
|
1
|
0
|
| DDC
|
1
|
1
|
| HTR3C
|
1
|
0
|
| EMP1
|
1
|
0
|
| SACM1L
|
1
|
0
|
| SIRT1
|
1
|
0
|
| MDGA1
|
1
|
0
|
| GRID2
|
1
|
0
|
| GPHN
|
1
|
0
|
| SEC23IP
|
1
|
0
|
| MEF2C
|
1
|
0
|
| ITGB3
|
1
|
0
|
| GSTK1
|
1
|
0
|
| Htt
|
1
|
0
|
| HSPA1B
|
1
|
0
|
| IL3
|
1
|
0
|
| ABCC1
|
1
|
0
|
| NTRK3
|
1
|
0
|
| PAWR
|
1
|
0
|
| SLC29A3
|
1
|
0
|
| MAP2K7
|
1
|
0
|
| AS3MT
|
1
|
0
|
| KIAA1549
|
1
|
0
|
| RFX3
|
1
|
1
|
| ROBO2
|
1
|
0
|
| OR10R1P
|
1
|
0
|
| ND2
|
1
|
0
|
| LGI1
|
1
|
0
|
|
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number
in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder
reflects all text searches of the disease term including the indexed term.
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