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Phenopedia


Depressive Disorder, Major

510 genes has been reported with Depressive Disorder, Major
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Associated Gene
Total Publication
Meta-analysis Publication
    SLC6A4 Genopedia 202 5
    BDNF Genopedia 95 6
    COMT Genopedia 58 3
    HTR2A Genopedia 55 8
    HTR1A Genopedia 43 3
    TPH1 Genopedia 32 6
    SLC6A2 Genopedia 29 3
    MAOA Genopedia 27 3
    TPH2 Genopedia 27 2
    CYP2D6 Genopedia 21 0
    ABCB1 Genopedia 21 2
    FKBP5 Genopedia 20 2
    NR3C1 Genopedia 20 0
    APOE Genopedia 20 1
    CRHR1 Genopedia 18 1
    GNB3 Genopedia 17 3
    MTHFR Genopedia 15 1
    CREB1 Genopedia 15 0
    DRD2 Genopedia 14 0
    CACNA1C Genopedia 14 4
    ACE Genopedia 14 1
    CYP2C19 Genopedia 12 0
    PCLO Genopedia 11 1
    SLC6A3 Genopedia 11 1
    GSK3B Genopedia 10 0
    CLOCK Genopedia 9 1
    DRD4 Genopedia 9 0
    DRD3 Genopedia 9 1
    MDD1 Genopedia 9 0
    NTRK2 Genopedia 7 0
    DISC1 Genopedia 7 0
    NRG1 Genopedia 6 1
    HTR1B Genopedia 6 0
    HTR6 Genopedia 6 2
    AGTR1 Genopedia 6 0
    IL1B Genopedia 6 1
    CYP2C9 Genopedia 6 0
    DTNBP1 Genopedia 6 0
    P2RX7 Genopedia 6 0
    ANK3 Genopedia 5 2
    HTR2C Genopedia 5 0
    CYP1A2 Genopedia 5 0
    GRM7 Genopedia 5 2
    DAOA Genopedia 5 0
    HTT Genopedia 5 0
    CNR1 Genopedia 5 0
    TNF Genopedia 5 0
    OPRM1 Genopedia 4 0
    DBH Genopedia 4 0
    BICC1 Genopedia 4 1
    ADRA2A Genopedia 4 0
    CRY2 Genopedia 4 0
    DRD1 Genopedia 4 0
    AVPR1B Genopedia 4 0
    HTR3A Genopedia 4 1
    IL10 Genopedia 4 0
    VEGFA Genopedia 4 0
    CRHR2 Genopedia 4 0
    ESR1 Genopedia 4 0
    NGFR Genopedia 4 0
    FTO Genopedia 4 2
    CRH Genopedia 3 0
    PER3 Genopedia 3 0
    IFNG Genopedia 3 0
    GAL Genopedia 3 1
    GABRA6 Genopedia 3 0
    GRIA4 Genopedia 3 0
    GRIK4 Genopedia 3 0
    CRY1 Genopedia 3 0
    TSNAX Genopedia 3 0
    PER2 Genopedia 3 0
    AR Genopedia 3 0
    HTR3B Genopedia 3 1
    CRHBP Genopedia 3 0
    EHD3 Genopedia 3 0
    IL6 Genopedia 3 0
    SLC6A15 Genopedia 3 1
    OXTR Genopedia 3 0
    ESR2 Genopedia 3 0
    CCL2 Genopedia 3 0
    GPR50 Genopedia 3 0
    NOS3 Genopedia 2 0
    NOVA2 Genopedia 2 0
    PTPRR Genopedia 2 0
    BCR Genopedia 2 0
    FGFR2 Genopedia 2 0
    ADCYAP1 Genopedia 2 0
    GRIK3 Genopedia 2 1
    GABRA3 Genopedia 2 0
    C5orf20 Genopedia 2 1
    PPARGC1A Genopedia 2 0
    UCN3 Genopedia 2 0
    ELK3 Genopedia 2 1
    IL19 Genopedia 2 0
    ZNF804A Genopedia 2 1
    TH Genopedia 2 0
    SP4 Genopedia 2 0
    BCL2 Genopedia 2 0
    S100B Genopedia 2 0
    ADSL Genopedia 2 1
    GRN Genopedia 2 1
    CHRM2 Genopedia 2 0
    ADM Genopedia 2 0
    ARNTL Genopedia 2 0
    MAPT Genopedia 2 1
    IL2 Genopedia 2 0
    KCNK2 Genopedia 2 0
    ANPEP Genopedia 2 0
    IKBKE Genopedia 2 0
    ITIH3 Genopedia 2 1
    PER1 Genopedia 2 0
    NOS1 Genopedia 2 0
    SAT1 Genopedia 2 0
    EGF Genopedia 2 0
    FGF2 Genopedia 2 0
    ZEB2 Genopedia 2 0
    HSPA1A Genopedia 2 0
    TP53 Genopedia 2 0
    PSMD9 Genopedia 2 0
    CTLA4 Genopedia 2 0
    ADRA2C Genopedia 2 0
    AGT Genopedia 2 0
    CNR2 Genopedia 2 0
    GAD1 Genopedia 2 0
    NPY Genopedia 2 0
    PDE11A Genopedia 2 0
    PGP Genopedia 2 1
    GRIA2 Genopedia 2 0
    GRIA3 Genopedia 2 0
    ADCY3 Genopedia 2 1
    ADCY9 Genopedia 2 0
    FAAH Genopedia 2 0
    HTR5A Genopedia 2 0
    PDE9A Genopedia 2 0
    CTNNA3 Genopedia 2 1
    NR3C2 Genopedia 2 0
    CSMD1 Genopedia 2 1
    NR1D1 Genopedia 2 0
    CCKAR Genopedia 2 0
    CACNB2 Genopedia 2 1
    C7orf49 Genopedia 2 0
    SNAP25 Genopedia 2 0
    AKT1 Genopedia 2 0
    IL11 Genopedia 2 0
    HSPA1L Genopedia 2 0
    LSAMP Genopedia 2 0
    SYNE1 Genopedia 2 2
    GABRG2 Genopedia 2 0
    TGFB1 Genopedia 2 0
    POMC Genopedia 2 0
    PRKCG Genopedia 2 0
    AVP Genopedia 2 0
    NPAS2 Genopedia 2 0
    RORA Genopedia 2 0
    FANCI Genopedia 1 0
    STK32B Genopedia 1 0
    DLK2 Genopedia 1 0
    SOD2 Genopedia 1 0
    STAT3 Genopedia 1 0
    PRODH Genopedia 1 0
    KIAA1244 Genopedia 1 0
    RIT2 Genopedia 1 0
    GNB1L Genopedia 1 0
    NOS2 Genopedia 1 0
    VCP Genopedia 1 0
    VIP Genopedia 1 0
    VIPR2 Genopedia 1 0
    RGS18 Genopedia 1 0
    NUCKS1 Genopedia 1 0
    Crh Genopedia 1 0
    KMO Genopedia 1 0
    CHRFAM7A Genopedia 1 0
    CD3E Genopedia 1 0
    DLGAP1 Genopedia 1 0
    NDST3 Genopedia 1 0
    NRXN1 Genopedia 1 0
    MAGI2 Genopedia 1 0
    SV2B Genopedia 1 0
    BRP44 Genopedia 1 1
    GCH1 Genopedia 1 0
    GRIP1 Genopedia 1 0
    GABRE Genopedia 1 0
    NXPH1 Genopedia 1 0
    CFH Genopedia 1 1
    HTR1D Genopedia 1 0
    SKA2 Genopedia 1 0
    C15orf53 Genopedia 1 1
    IL20 Genopedia 1 0
    PAM Genopedia 1 0
    ACP1 Genopedia 1 0
    ATP6V0A1 Genopedia 1 1
    SNTG2 Genopedia 1 0
    FGF14 Genopedia 1 0
    CLASP2 Genopedia 1 0
    MACROD2 Genopedia 1 0
    ADRB2 Genopedia 1 0
    SLC35G1 Genopedia 1 1
    DGKH Genopedia 1 0
    DPP4 Genopedia 1 0
    AGTR2 Genopedia 1 0
    CDH9 Genopedia 1 0
    ADCY2 Genopedia 1 0
    CPLX1 Genopedia 1 0
    CHRNA7 Genopedia 1 0
    ACSM1 Genopedia 1 0
    CNP Genopedia 1 0
    CPM Genopedia 1 0
    CREBBP Genopedia 1 0
    SPR Genopedia 1 1
    TERT Genopedia 1 0
    UCN Genopedia 1 0
    PPP1R1B Genopedia 1 0
    ABCG1 Genopedia 1 0
    USP46 Genopedia 1 0
    MAGI1 Genopedia 1 0
    ABCC1 Genopedia 1 0
    NPY2R Genopedia 1 0
    ORM1 Genopedia 1 0
    Htt Genopedia 1 0
    PLA2G4A Genopedia 1 0
    SLC29A3 Genopedia 1 0
    MCTP2 Genopedia 1 0
    GABRQ Genopedia 1 0
    CELF4 Genopedia 1 1
    AKTIP Genopedia 1 0
    GMIP Genopedia 1 0
    PDE1A Genopedia 1 0
    SACM1L Genopedia 1 0
    SIRT1 Genopedia 1 0
    TMEM132D Genopedia 1 0
    DDC Genopedia 1 1
    ADCY4 Genopedia 1 0
    EMP1 Genopedia 1 0
    EMX2 Genopedia 1 0
    DEGS2 Genopedia 1 0
    ADORA1 Genopedia 1 0
    AFAP1L1 Genopedia 1 0
    AANAT Genopedia 1 0
    TMEM161B Genopedia 1 0
    ADA Genopedia 1 0
    TSNAX-DISC1 Genopedia 1 0
    ST3GAL6 Genopedia 1 0
    PDE10A Genopedia 1 0
    CNTNAP2 Genopedia 1 0
    GFRA1 Genopedia 1 0
    GRIA1 Genopedia 1 0
    ITGB3 Genopedia 1 0
    L1CAM Genopedia 1 0
    FADS1 Genopedia 1 0
    OR7E26P Genopedia 1 1
    LTA Genopedia 1 0
    ACCN2 Genopedia 1 0
    MEF2C Genopedia 1 0
    LEF1 Genopedia 1 0
    PDE4B Genopedia 1 0
    ABCB4 Genopedia 1 0
    NRAS Genopedia 1 0
    NRGN Genopedia 1 1
    ITGB1 Genopedia 1 0
    MC2R Genopedia 1 0
    TBX21 Genopedia 1 0
    GZMK Genopedia 1 0
    HTR2B Genopedia 1 0
    PABPC4L Genopedia 1 0
    SGCZ Genopedia 1 0
    GRIK2 Genopedia 1 0
    CMYA5 Genopedia 1 0
    PTK2B Genopedia 1 0
    EFEMP1 Genopedia 1 0
    TBC1D1 Genopedia 1 0
    GABRP Genopedia 1 0
    CUX1 Genopedia 1 0
    IL28RA Genopedia 1 0
    TOMM40 Genopedia 1 0
    NRG3 Genopedia 1 0
    CHL1 Genopedia 1 0
    IL24 Genopedia 1 0
    ADCY5 Genopedia 1 0
    ADCY6 Genopedia 1 0
    ADCYAP1R1 Genopedia 1 0
    SLC4A10 Genopedia 1 0
    ND6 Genopedia 1 0
    STK3 Genopedia 1 0
    TAP2 Genopedia 1 0
    TCF4 Genopedia 1 0
    TEF Genopedia 1 0
    SAGE1 Genopedia 1 0
    ATF7IP Genopedia 1 0
    PSMA7 Genopedia 1 0
    PSMB4 Genopedia 1 0
    APOO Genopedia 1 0
    NR4A3 Genopedia 1 0
    AXIN2 Genopedia 1 0
    BHLHE40 Genopedia 1 0
    PDE5A Genopedia 1 0
    NRP1 Genopedia 1 0
    CD38 Genopedia 1 0
    DMTF1 Genopedia 1 1
    TSC2 Genopedia 1 0
    WFS1 Genopedia 1 1
    YWHAE Genopedia 1 0
    CACNA1A Genopedia 1 1
    KCNIP4 Genopedia 1 0
    TRPA1 Genopedia 1 0
    UCN2 Genopedia 1 0
    PPIG Genopedia 1 0
    GAD2 Genopedia 1 0
    GRIK1 Genopedia 1 0
    APC Genopedia 1 0
    HP Genopedia 1 0
    EGFR Genopedia 1 0
    ELAVL1 Genopedia 1 0
    NCAN Genopedia 1 0
    UST Genopedia 1 0
    CDH17 Genopedia 1 0
    PDLIM5 Genopedia 1 0
    CPLX2 Genopedia 1 0
    OR4B1 Genopedia 1 0
    ADORA2A Genopedia 1 0
    CRP Genopedia 1 0
    SRR Genopedia 1 0
    SLIT3 Genopedia 1 0
    NTSR1 Genopedia 1 0
    TMEM66 Genopedia 1 0
    PARP14 Genopedia 1 0
    PSEN1 Genopedia 1 0
    PSMD13 Genopedia 1 0
    BCL9 Genopedia 1 0
    ITIH4 Genopedia 1 0
    MIR19A Genopedia 1 0
    ATXN3 Genopedia 1 0
    NDUFV2 Genopedia 1 0
    NFATC2 Genopedia 1 0
    IGFBP3 Genopedia 1 0
    NQO1 Genopedia 1 0
    DIO1 Genopedia 1 0
    VSTM5 Genopedia 1 1
    GSTK1 Genopedia 1 0
    SORL1 Genopedia 1 1
    CYTB Genopedia 1 0
    ND4L Genopedia 1 0
    ND2 Genopedia 1 0
    SYN2 Genopedia 1 0
    WNT7A Genopedia 1 0
    SDPR Genopedia 1 0
    LGI1 Genopedia 1 0
    MMP8 Genopedia 1 0
    NTRK3 Genopedia 1 0
    PAWR Genopedia 1 0
    PON1 Genopedia 1 0
    ELP3 Genopedia 1 0
    CSGALNACT1 Genopedia 1 0
    MAPK1 Genopedia 1 0
    MAP2K1 Genopedia 1 0
    SLC17A7 Genopedia 1 0
    AS3MT Genopedia 1 0
    RNR1 Genopedia 1 0
    RPS6KA2 Genopedia 1 0
    PRDM1 Genopedia 1 0
    SLC6A1 Genopedia 1 0
    PXDNL Genopedia 1 0
    ADAMTS14 Genopedia 1 0
    CTNND2 Genopedia 1 0
    ABCA13 Genopedia 1 0
    FREM3 Genopedia 1 0
    HTR3C Genopedia 1 0
    ADAMTS16 Genopedia 1 0
    DIO2 Genopedia 1 0
    AHCY Genopedia 1 0
    NLGN1 Genopedia 1 1
    GAP43 Genopedia 1 0
    MDGA1 Genopedia 1 0
    C10orf32 Genopedia 1 0
    ADK Genopedia 1 0
    ABCB6 Genopedia 1 0
    CDH12 Genopedia 1 0
    SLC29A2 Genopedia 1 0
    HSPA1B Genopedia 1 0
    IGLV2-8 Genopedia 1 0
    GRIN2B Genopedia 1 0
    APAF1 Genopedia 1 0
    TAAR6 Genopedia 1 0
    MIR182 Genopedia 1 0
    MIR30E Genopedia 1 0
    M6PR Genopedia 1 0
    MAOB Genopedia 1 0
    OR1D2 Genopedia 1 1
    SERPINE1 Genopedia 1 0
    RHCG Genopedia 1 0
    PDE6C Genopedia 1 0
    FIGN Genopedia 1 0
    CCBL2 Genopedia 1 0
    ARNTL2 Genopedia 1 0
    TBX20 Genopedia 1 0
    WDFY4 Genopedia 1 0
    RGS4 Genopedia 1 0
    RPS6KA1 Genopedia 1 0
    MDGA2 Genopedia 1 0
    CNTF Genopedia 1 0
    CSNK1E Genopedia 1 0
    HPRTP4 Genopedia 1 1
    CDH7 Genopedia 1 1
    TSPAN5 Genopedia 1 1
    SIGMAR1 Genopedia 1 0
    ADARB1 Genopedia 1 0
    KLHL2 Genopedia 1 1
    DVL2 Genopedia 1 0
    EPHB1 Genopedia 1 0
    FABP2 Genopedia 1 0
    ACSL4 Genopedia 1 0
    MYT1L Genopedia 1 0
    Slc6a4 Genopedia 1 0
    PRPF31 Genopedia 1 1
    ZBTB20 Genopedia 1 0
    TCTA Genopedia 1 0
    TFCP2 Genopedia 1 0
    TSPO Genopedia 1 0
    XBP1 Genopedia 1 0
    DLK1 Genopedia 1 0
    SLC6A5 Genopedia 1 0
    DDX21 Genopedia 1 0
    FADS2 Genopedia 1 0
    UBE3C Genopedia 1 0
    GPRIN2 Genopedia 1 0
    CDC25B Genopedia 1 0
    SLC5A4 Genopedia 1 0
    BMP5 Genopedia 1 0
    BMP7 Genopedia 1 0
    STIM1 Genopedia 1 0
    SULT2A1 Genopedia 1 0
    PLXNA2 Genopedia 1 0
    TTR Genopedia 1 0
    REEP5 Genopedia 1 0
    C7orf23 Genopedia 1 1
    FAT4 Genopedia 1 1
    FZD3 Genopedia 1 0
    OR2G2 Genopedia 1 1
    TIMELESS Genopedia 1 0
    SLC28A2 Genopedia 1 0
    NT5C1B Genopedia 1 0
    HTR3D Genopedia 1 0
    ENPEP Genopedia 1 0
    ERBB4 Genopedia 1 0
    SLC29A4 Genopedia 1 0
    DBP Genopedia 1 0
    IDO2 Genopedia 1 0
    CYP3A4 Genopedia 1 0
    CDH10 Genopedia 1 0
    CDH13 Genopedia 1 0
    ADRA1A Genopedia 1 0
    ADRB3 Genopedia 1 0
    VPS33B Genopedia 1 0
    GDNF Genopedia 1 0
    ZBTB32 Genopedia 1 0
    GNAS Genopedia 1 0
    HTR3E Genopedia 1 0
    GRM8 Genopedia 1 1
    FASLG Genopedia 1 0
    ANKK1 Genopedia 1 0
    SLC2A9 Genopedia 1 0
    RGMA Genopedia 1 0
    DTWD1 Genopedia 1 0
    IDO1 Genopedia 1 0
    ITIH1 Genopedia 1 0
    ARRB1 Genopedia 1 0
    NCAM1 Genopedia 1 0
    PCNT Genopedia 1 0
    PDE2A Genopedia 1 0
    GRIN2A Genopedia 1 0
    MTRR Genopedia 1 0
    ELAVL4 Genopedia 1 0
    SLC29A1 Genopedia 1 0
    LGSN Genopedia 1 0
    AVPR1A Genopedia 1 0
    PRKCH Genopedia 1 0
    PRNP Genopedia 1 1
    PSME2 Genopedia 1 0
    PTGS2 Genopedia 1 0
    DPP10 Genopedia 1 0
    SLCO6A1 Genopedia 1 0
    CREM Genopedia 1 0
    CSF2RB Genopedia 1 0
    ADAR Genopedia 1 0
    ADCY1 Genopedia 1 0
    FOXN3 Genopedia 1 0
    PRKCDBP Genopedia 1 0
    ADCY7 Genopedia 1 0
    ADCY8 Genopedia 1 0
    SMCHD1 Genopedia 1 0
    CRTC1 Genopedia 1 0
    GABRA2 Genopedia 1 0
    TIPRL Genopedia 1 1
    DAOA-AS1 Genopedia 1 0
    NKPD1 Genopedia 1 1
    GPX1 Genopedia 1 0
    S100A10 Genopedia 1 0
    NT5E Genopedia 1 0
    SLC7A4 Genopedia 1 0
    SLC16A2 Genopedia 1 0
    VAMP2 Genopedia 1 0
    TARBP2 Genopedia 1 0
    TGFBR2 Genopedia 1 0
    ZNF80 Genopedia 1 0
    FOXP2 Genopedia 1 0
    HOMER1 Genopedia 1 0
    LHPP Genopedia 1 0
    BHLHE41 Genopedia 1 0
    ACSS3 Genopedia 1 0
    PAPLN Genopedia 1 0
    SLC28A1 Genopedia 1 0
Note: The number of publications displayed in this table will differ from the number displayed in the HuGE Literature Finder as the number in Phenopedia reflects only the indexed disease term, but the number in the HuGE Literature Finder reflects all text searches of the disease term including the indexed term.
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