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COVID-19 GPH|Home|PHGKB Last data update: Dec 02, 2022 . (Total: 41679 Documents since 2020)

Last Posted: Dec-02-2022 11:58:37
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The Detection of COVID-19 in Chest X-Rays Using Ensemble CNN Techniques
D Kuzinkovas et al, MEDRXIV, December 2, 2022

We present a model trained on the COVID-QU-Ex dataset, overall containing 33,920 chest x-ray images, with an equal share of COVID-19, Non-COVID pneumonia, and Normal images. The model itself is an ensemble of pre-trained CNNs (ResNet50, VGG19, VGG16) and GLCM textural features. It achieved a 98.34% binary classification accuracy (COVID-19/no COVID-19) on a balanced test dataset of 6581 chest x-rays, and 94.68% for distinguishing between COVID-19, Non-COVID pneumonia and normal chest x-rays.

Six-Month Follow-up after a Fourth BNT162b2 Vaccine Dose.
Canetti Michal et al. The New England journal of medicine 2022 11 (22) 2092-2094

In this prospective cohort study, a third dose of the BNT162b2 vaccine led to an improved and sustained immunologic response as compared with two doses, but the additional immunologic advantage of the fourth dose was much smaller and had waned completely by 13 weeks after vaccination. This finding correlated with waning vaccine effectiveness among recipients of a fourth dose, which culminated in no substantial additional effectiveness over a third dose at 15 to 26 weeks after vaccination.

A systematic review and meta-analysis comparing the diagnostic accuracy tests of COVID-19
JJV Alosilla et al, MEDRXIV, November 29, 2022

Molecular tests [Reverse transcription polymerase chain reaction (RT-PCR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and clustered regularly interspaced short palindromic repeats (CRISPR)] showed better performance in terms of sensitivity and specificity when compared to serological tests.

Wastewater genomic surveillance captures early detection of Omicron in Utah
P Gupta et al, MEDRXIV, November 29, 2022

Here, we investigated the spread of SARS-CoV-2 infections across Utah by characterizing lineages and mutations detected in wastewater samples. We sequenced over 1,200 samples from 32 sewersheds collected between November 2021 and March 2022. Wastewater sequencing confirmed the presence of Omicron (B.1.1.529) in Utah in samples collected on November 19, 2021, up to seven days before its corresponding detection via clinical sequencing.

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SARS-CoV-2 Variants in COVID-19 Disease: A Focus on Disease Severity and Vaccine Immunity in Patients Admitted to the Emergency Department
M Fogoloari et al, J Per Med, December 2, 2022

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Supervised Machine Learning Approach to COVID-19 Detection Based on Clinical Data.
Yazdani Azita, et al. Medical journal of the Islamic Republic of Iran 2022 0 0. 110

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Identifying Profiles and Symptoms of Patients With Long COVID in France: Data Mining Infodemiology Study Based on Social Media.
Déguilhem Amélia, et al. JMIR infodemiology 2022 0 0. (2) e39849

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COVID-19 detection on chest X-ray images using Homomorphic Transformation and VGG inspired deep convolutional neural network.
Shibu George Gerosh, et al. Biocybernetics and biomedical engineering 2022 0 0.

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Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning.
Duong Linh T, et al. Applied soft computing 2022 0 0. 109851

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Application of deep learning-based diagnostic systems in screening asymptomatic COVID-19 patients among oversea returnees.
Dong Dawei, et al. Journal of infection in developing countries 2022 0 0. (11) 1706-1714

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Highly Adsorptive Au-TiO Nanocomposites for the SERS Face Mask Allow the Machine-Learning-Based Quantitative Assay of SARS-CoV-2 in Artificial Breath Aerosols.
Hwang Charles S H, et al. ACS applied materials & interfaces 2022 0 0.

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3D CT-Inclusive Deep-Learning Model to Predict Mortality, ICU Admittance, and Intubation in COVID-19 Patients.
Di Napoli Alberto, et al. Journal of digital imaging 2022 0 0.

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Clinical characteristics and short-term mortality of 102 hospitalized hemodialysis patients infected with SARS-CoV-2 omicron BA.2.2.1 variant in Shanghai, China.
Bao Wen Jing, et al. New microbes and new infections 2022 0 0. 101058

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The immunodominance of RBD antigen of delta variant as vaccine candidate against SARS-CoV-2 infection.
Luo Deyan, et al. Journal of medical virology 2022 0 0.

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About COVID-19 GPH

COVID-19 GPH is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other materials that capture emerging discoveries and applications of genomics, molecular and other precision medicine and precision public health tools in the investigation and control of COVID-19. Contents include PubMed records via an automated pubmed search algorithm, preprint records from NIH iCite, the relevant information from many media sources picked by experts, and linkages to contents from our curated PHGKB databases.

Site Citation:
Wei Yu, et al. COVID-19 GPH: tracking the contribution of genomics and precision health to the COVID-19 pandemic response. BMC Infectious Diseases (2022) 22:402.

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All Records41679
Genomics Precision Health30348
Non-Genomics Precision Health11331

Publication Categories Brand

Variants 11711
Vaccines 10123
Mechanism 9323
Treatment 9286
Diagnosis 6788
Prevention 5005
Surveillance 3661
Forecasting 3264
Transmission 1999
Health Equity 1070

Publication Types

PubMed Records31456
Online News/Reports/Publications431

Genomics Precision Health (GPH): The use of pathogen and human genomics and advanced molecular detection methods in discovery, clinical and public health investigations and response to COVID-19.
Non Genomics Precision Health (non-GPH): The use of big data, data science, digital health, machine learning and predictive analytic methods (not involving genomics) in discovery, clinical and public health investigations and response to COVID-19

Following categories are annotated by LitCovid from NCBI NIH.
MechanismUnderlying cause(s) of covid-19 infections and transmission & possible drug mechanism of action
Transmission Characteristics and modes of covid-19 transmissions, such as human-to-human
DiagnosisDisease assessment through symptoms, test results, and radiological features
PreventionPrevention, control, response and management strategies
Case ReportDescriptions of specific patient cases
ForecastingModelling and estimating the trend of covid-19 spread

Following categories are annotated by the text mining tool from CDC PHGKB
Health EquityRelevant to health equity. Search terms are derived from a list provided by the Association for Territorial Health Officials which include terms such as diversity, health disparities, and others.
VaccineRelevant to vaccine development, evaluation, implementation and impact. For additional information on vaccines and COVID-19. Check out general CDC Information pages
VariantRelevant to SARS-CoV-2 variants and their impact on public health. For additional information on variants COVID-19. Check out CDC New Variants of the Virus that Causes COVID-19 page
SurveillanceRelevant to SARS-CoV-2 public health surveillance and tracking. For additional information on COVID-19 surveillance, check out CDC COVID-19 Data Tracker

Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Office of Genomics and Precision Public Health to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.