Records 1-12 (of 12 Records) |
Query Trace: Ighv1-9[original query] |
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Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Pushparaj Pradeepa, et al. Immunity 2022 0 0. |
Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants. Yan Qihong, et al. Emerging microbes & infections 2022 0 0. 1-41 |
Identification of Novel Therapeutic Candidates Against SARS-CoV-2 Infections: An Application of RNA Sequencing Toward mRNA Based Nanotherapeutics. Khalid Zunera, et al. Frontiers in microbiology 2022 0 0. 901848 |
A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge. Zhou Biao, et al. Nature communications 2022 0 0. (1) 3589 |
Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees. Andreano Emanuele, et al. Nature communications 2022 0 0. (1) 3375 |
Anti-SARS-CoV-2 Omicron Antibodies Isolated from a SARS-CoV-2 Delta Semi-Immune Phage Display Library. Mendoza-Salazar Ivette, et al. Antibodies (Basel, Switzerland) 2022 0 0. (1) |
Ultrapotent SARS-CoV-2 neutralizing antibodies effectively block new-emerging mutational variants Jin, Aishun et al. Research Square February 12 2021 |
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants Li, Tingting et al. bioRxiv April 20 2021 |
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Yuan Meng et al. Science (New York, N.Y.) 2021 5
Neutralizing antibodies (nAbs) elicited against the receptor-binding site (RBS) of the spike protein of wild-type SARS-CoV-2 are generally less effective against recent variants of concern. RBS residues E484, K417 and N501 are mutated in variants first described in South Africa (B.1.351) and Brazil (P.1). We analyzed their effects on ACE2 binding and K417N and E484K mutations on nAbs isolated from COVID-19 patients. Binding and neutralization of the two most frequently elicited antibody families (IGHV3-53/3-66 and IGHV1-2), which can both bind the RBS in alternate binding modes, are abrogated by K417N, E484K, or both.
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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Yuan Meng, et al. bioRxiv : the preprint server for biology 2021 2 0. |
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma. Voss William N, et al. bioRxiv : the preprint server for biology 2020 12 0. |
Computational methods to develop potential neutralizing antibody Fab region against SARS-CoV-2 as therapeutic and diagnostic tool Manikyam, Hemanth K et al. bioRxiv May 04 2020 |
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